charged aerosol detection bibliography
TRANSCRIPT
Charged Aerosol Detection BibliographyPharmaceutical Polymers/
Surfactants
both routine and complex analyses. This bibliography
is designed to readily show the analytical capabilities of
charged aerosol detection and highlights the breadth
and scope of the different analytical methods found
in the literature.
For ease of use, the document is divided into different
categories based on either the family of analytes being
measured (e.g., carbohydrates, lipids, surfactants)
or the relevant market place (e.g., Food/Nutrition,
Pharmaceutical) being served. Each publication is
hyperlinked so that you can obtain more information
about the article including analytes being measured and
sample matrices.
Pharmaceutical Polymers/ Surfactants
ideal results. Often, one analyte responds more strongly
than another, or may not respond at all. UV absorbance
detection requires that the molecule contain a chromo-
phore and Inter-analyte response can vary greatly
depending upon the nature of the chromophore present.
Refractive index detection cannot be used with gradient
elution and is temperature sensitive.
Mass spectrometry can only measure compounds that
will form gas-phase ions.
analyte response and complex, non-linear calibration
curves.
What is most desired in a universal detector is the
ability to accurately measure a wide range of analytes
with consistent response. Charged aerosol detection
can measure any non-volatile and most semi-volatile
analytes at sub-nanogram levels and does not require
a compound to contain a chromophore or be able
to ionize. Variance in inter-analyte relative response
is minimal whether analyzing small molecules or
proteins. The technique is fully compatible with gradient
chromatography.
Introduction
Introduction Antibiotics Carbohydrates Food/Nutrition General Lipids Miscellaneous Natural Products/ Supplements
Pharmaceutical Polymers/ Surfactants
the column. Large droplets exit the detector to waste.
Selected smaller droplets enter the evaporation tube and
form particles once the solvent is evaporated. Particles
then enter a reaction chamber where they collide with
ionized gas formed when nitrogen is passed over a corona
wire. Charge is transferred from the ionized gas to the
analyte particles. Once unreacted ionized gas is removed
by an ion trap, the charge on the particle is measured by
a sensitive electrometer. The response of the detector
is directly related to the mass of the analyte entering the
detector. An increase in the amount of an analyte eluting
from the column leads to an increase in the size of the
particles being formed. Larger particles can accommodate
more charge, resulting in a higher response from the
detector. As long as the analyte will form a particle it will be
measured by charged aerosol detection, independent of
its chemical structure.
without the need for complex detector optimization and
has the flexibility to measure a broad range of analytes in
many different matrices. The Thermo Scientific™ Dionex™
Corona™ Veo™ charged aerosol detector is HPLC/UHPLC
compatible and with its extended flow rate range, can
be used with capillary, microbore, and analytical-scale
columns. The detector improves on all the benefits of
charged aerosol detection in a design perfectly matched to
your laboratory’s needs.
How the Technology Works
Pharmaceutical Polymers/ Surfactants
Pharmaceutical Polymers/ Surfactants
Title Authors Publication Publication Date
Production of surfactin and iturin by Bacillus licheniformis N1 responsible for plant disease control activity.
Gi Kong, H.; Kim, J.; Choi, G.; Lee, K.; Kim, H.; Hwang, E.; Moon, B.; Lee, S.
Plant Pathol. J. (Seoul, Repub. Korea) 26 (2), 170–177.
2010 Mar 21
J. Pharm. Biomed. Anal. 56 (2), 271–279.
2011 Sep 10
The effect of composting on the degradation of a veterinary pharmaceutical.
Jayashree, R.; Prasher, S.; Patel, R.; Hussain, S.; Barrington, S.
Bioresour. Technol. 101 (7), 2294–2299.
2010 Apr
Effect of soil pH on sorption of salinomycin in clay and sandy soils.
Jayashree, R.; Prasher, S.; Rajvinder, K.; Patel, R.
Afr. J. Environ. Sci. Technol. 5 (9), 661–667.
2011 Sep
Combined application of dispersive liquid-liquid microextraction based on the solidification of floating organic droplets and charged aerosol detection for the simple and sensitive quantification of macrolide antibiotics in human urine.
Jia, S.; Li, J.; Park, S. R.; Ryu, Y.; Park, I. H.; Park, J. H.; Hong, S. S.; Kwon, S. W.; Lee, J.
J. Pharm. Biomed. Anal. 86C, 204–213.
2013 Dec
Development and validation of a RP-HPLC method for the estimation of netilmicin sulfate and its related substances using charged aerosol detection.
Joseph, A.; Patel, S.; Rustum, A. J. Chromatogr. Sci. 48 (7), 607–612.
2010 Aug
Development and validation of a RP-HPLC method for the determination of gentamicin sulfate and its related substances in a pharmaceutical cream using a short pentafluorophenyl column and a charged aerosol detector.
Joseph, A.; Rustum, A. J. Pharm. Biomed. Anal. 51 (3), 521–531.
2010 Feb 5
Polyketide analysis using mass spectrometry, evaporative light scattering, and charged aerosol detector systems.
Pistorino, M.; Pfeifer, B. A. Anal. Bioanal. Chem. 390 (4), 1189–1193.
2008 Feb
Stypulkowska, K.; Blazewicz, A.; Fijalek, Z.; Sarna, K.
Chromatographia 72 (11– 12), 1225–1229.
2010 Dec
J. Pharm. Biomed. Anal. 76, 207–214.
2013 Mar 25
Biosynthesis of fosfomycin, re-examination and re- confirmation of a unique Fe (II) and NAD (P) H-dependent epoxidation reaction.
Yan, F.; Munos, J.; Liu, P.; Liu, H. Biochemistry 45 (38), 11473–11481.
2006 Sep 26
Pharmaceutical Polymers/ Surfactants
Pharmaceutical Polymers/ Surfactants
Carbohydrate and oligosaccharide analysis with a universal HPLC detector.
Asa, D. American Laboratory 38, 16.
2006
Determination of levoglucosan in atmospheric aerosols using high performance liquid chromatography with aerosol charge detection.
Dixon, R. W.; Baltzell, G. J. Chromatogr., A. 1109 (2), 214–221.
2006 Mar 24
Composition of structural carbohydrates in biomass: Precision of a liquid chromatography method using a neutral detergent extraction and a charged aerosol detector.
Godin, B.; Agneessens, R.; Gerin, P. A.; Delcarte, J.
Talanta 85 (4), 2014–2026. 2011 Sep 30
Selectivity issues in targeted metabolomics: Separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography.
Hinterwirth, H.; Lämmerhofer, M.; Preinerstorfer, B.; Gargano, A.; Reischl, R.; Bicker, W.; Trapp, O.; Brecker, L.; Lindner, W.
J. Sep. Sci. 33 (21), 3273– 3282.
2010 Nov
Investigation of polar organic solvents compatible with Corona charged aerosol detection and their use for the determination of sugars by hydrophilic interaction liquid chromatography.
Hutchinson, J. P.; Remenyi, T.; Nesterenko, P.; Farrell, W.; Groeber, E.; Szucs, R.; Dicinoski, G.; Haddad, P. R.
Anal. Chim. Acta. 750, 199–206.
2012 Oct 31
Characterization of an endoglucanase belonging to a new subfamily of glycoside hydrolase family 45 of the basidiomycete Phanerochaete chrysosporium.
Igarashi, K.; Ishida, T.; Hori, C.; Samejima, M.
Appl. Environ. Microbiol. 74 (18), 5628–5634.
2008 Sep
Direct detection method of oligosaccharides by high- performance liquid chromatography with charged aerosol detection.
Inagaki, S.; Min, J. Z.; Toyo’oka, T. Biomed. Chromatogr. 21 (4), 338–342.
2007 Apr
Differential selectivity of the Escherichia coli cell membrane shifts the equilibrium for the enzyme-catalyzed isomerization of galactose to tagatose.
Kim, J. H.; Lim, B. C.; Yeom, S. J.; Kim, Y. S.; Kim, H. J.; Lee, J. K.; Lee, S. H.; Kim, S. W.; Oh, D. K.
Appl. Environ. Microbiol. 74 (8), 2307–2313.
2008 Apr
Elution strategies for reversed-phase high-performance liquid chromatography analysis of sucrose alkanoate regioisomers with charged aerosol detection.
Lie, A.; Pedersen, L. H. J. Chromatogr., A. 1311, 127–133.
2013 Oct 11
Pharmaceutical Polymers/ Surfactants
Design of experiments and multivariate analysis for evaluation of reversed-phase high-performance liquid chromatography with charged aerosol detection of sucrose caprate regioisomers.
Lie, A.; Wimmer, R.; Pedersen, L. H.
J. Chromatogr., A. 1281, 67–72.
2013 Mar 15
Solvent effects on the retention of oligosaccharides in porous graphitic carbon liquid chromatography.
Melmer, M.; Stangler, T.; Premstaller, A.; Lindner, W.
J. Chromatogr., A 1217 (39) 6092–6096.
2010 Sep 24
Practical preparation of lacto-N-biose I, a candidate for the bifidus factor in human milk.
Nishimoto, M.; Kitaoka, M. Biosci., Biotechnol., Biochem. 71 (8), 2101– 2104.
2007 Aug
Suzuki, H.; Igarashi, K.; Samejima, M.
Appl. Environ. Microbiol. 76 (18), 6164–6170.
2010 Sep
1,2-alpha-l-Fucosynthase: A glycosynthase derived from an inverting alpha-glycosidase with an unusual reaction mechanism.
Wada, J.; Honda, Y.; Nagae, M.; Kato, R.; Wakatsuki, S.; Katayama, T.; Taniguchi, H.; Kumagai, H.; Kitaoka, M.; Yamamoto, K.
FEBS Lett. 582 (27), 3739– 3743.
2008 Nov 12
Efficient separation of oxidized cello-oligosaccharides generated by cellulose degrading lytic polysaccharide monooxygenases.
Westereng, B.; Agger, J. W.; Horn, S. J.; Vaaje-Kolstad, G.; Aachmann, F. L.; Stenstrøm, Y. H.; Eijsink, V. G.
J. Chromatogr., A. 1271 (1), 144–152.
2013 Jan 4
Distribution of in vitro fermentation ability of lacto-N-Biose I, a major building block of human milk oligosaccharides, in bifidobacterial strains.
Xiao, J. Z.; Takahashi, S.; Nishimoto, M.; Odamaki, T.; Yaeshima, T.; Iwatsuki, K.; Kitaoka, M.
Appl. Environ. Microbiol. 76 (1), 54–59.
2010 Jan
Pharmaceutical Polymers/ Surfactants
“Dilute-and-shoot” triple parallel mass spectrometry method for analysis of vitamin D and triacylglycerols in dietary supplements.
Byrdwell, W. C. Anal. Bioanal. Chem. 401 (10), 3317–3334.
2011 Dec
Photostability of rebaudioside A and stevioside in beverages. Clos, J. F.; Dubois, G. E.; Prakash, I.
J. Agric. Food Chem. 56 (18), 8507–8513.
2008 Sep 24
Assessment of microcystin purity using charged aerosol detection.
Edwards, C.; Lawton, L. A. J. Chromatogr., A. 1217 (32), 5233–5238.
2010 Aug 6
Charged aerosol detection to characterize components of dispersed-phase formulations.
Fox, C. B.; Sivananthan, S. J.; Mikasa, T. J.; Lin, S.; Parker, S. C.
Adv. Colloid Interface Sci. 199–200, 59–65.
2013 Nov
Determination of water-soluble vitamins in infant milk and dietary supplement using a liquid chromatography on-line coupled to a corona-charged aerosol detector.
Márquez-Sillero, I.; Cárdenas, S.; Valcárcel, M.
J. Chromatogr., A. 1313C, 253–258.
2013 Oct 25
Practical preparation of lacto-N-biose I, a candidate for the bifidus factor in human milk.
Nishimoto, M.; Kitaoka, M. Biosci., Biotechnol., Biochem. 71 (8), 2101- 2104.
2007 Aug
Nováková, L.; Solichová, D.; Solich, P.
J. Chromatogr., A. 1216 (21), 4574–4581.
2009 May 22
Pharmaceutical Polymers/ Surfactants
Comprehensive impurity profiling of nutritional infusion solutions by multidimensional off-line reversed-phase liquid chromatography × hydrophilic interaction chromatography-ion trap mass-spectrometry and charged aerosol detection with universal calibration.
Schiesel, S.; Lämmerhofer, M.; Lindner, W.
J. Chromatogr., A. 1259, 100–10.
2012 Oct 12
Direct separation and detection of biogenic amines by ion- pair liquid chromatography with chemiluminescent nitrogen detector.
Sun, J.; Guo, H. X.; Semin, D.; Cheetham, J.
J. Chromatogr., A. 1218 (29), 4689–4697.
2011 Jul 22
Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry.
Zhu, L.; Hu, Z.; Gamez, G.; Law, W. S.; Chen, H.; Yang, S.; Chingin, K.; Balabin, R. M.; Wang, R.; Zhang, T.; Zenobi, R.
Anal. Bioanal. Chem. 398 (1), 405–413.
2010 Sep
Pharmaceutical Polymers/ Surfactants
Title Authors Publication Publication Date
From lipid analysis towards lipidomics, a new challenge for the analytical chemistry of the 21st century. Part I: Modern lipid analysis.
Carrasco-Pancorbo, A.; Navas- Iglesias, N.; Cuadros-Rodríguez, L.
TrAC, Trends Anal. Chem. 28 (3), 263–278.
2009 Mar
Improving the universal response of evaporative light scattering detection by mobile phase compensation.
de Villiers, A.; Górecki, T.; Lynen, F.; Szucs, R.; Sandra, P.
J. Chromatogr., A. 1161 (1–2), 183–191.
2007 Aug 17
Development and testing of a detection method for liquid chromatography based on aerosol charging.
Dixon, R. W.; Peterson, D. S. Anal. Chem. 74 (13), 2930– 2937.
2002 Jul 1
Charged aerosol detection to characterize components of dispersed-phase formulations.
Fox, C. B.; Sivananthan, S. J.; Mikasa, T. J.; Lin, S.; Parker, S. C.
Adv. Colloid Interface Sci. 199–200, 59–65.
2013 Nov
HPLC analysis of nonvolatile analytes using charged aerosol detection.
Gamache, P.; McCarthy, R.; Freeto, S. M.; Asa, D.; Woodcock, M.; Laws, K.; Cole, R.
LC-GC North America 23, 150–161.
2005 Feb 1
Górecki, T.; Lynen, F.; Szucs, R.; Sandra, P.
Anal. Chem. 78 (9), 3186– 3192.
2006 May 1
2007 Nov 2
Comparison of the response of four aerosol detectors used with ultra high pressure liquid chromatography.
Hutchinson, J. P.; Li, J.; Farrell, W.; Groeber, E.; Szucs, R.; Dicinoski, G.; Haddad, P. R.
J. Chromatogr., A. 1218 (12), 1646–1655.
2011 Mar 25
Universal response model for a corona charged aerosol detector.
Hutchinson, J. P.; Li, J.; Farrell, W.; Groeber, E.; Szucs, R.; Dicinoski, G.; Haddad, P. R.
J. Chromatogr., A. 1217 (47), 7418–7427.
2010 Nov 19
Pharmaceutical Polymers/ Surfactants
Title Authors Publication Publication Date
Effects of eluent temperature and elution bandwidth on detection response for aerosol-based detectors.
Khandagale, M. M.; Hutchinson, J. P.; Dicinoski, G. W.; Haddad, P. R.
J. Chromatogr., A. 1308, 96–103.
2013 Sep 20
Development and evaluation of Corona charged aerosol detection (CAD): A new universal detector for HPLC.
McCarthy, R.; Gamache, P.; Asa, D.
LabPlus international. 2005 Jun
Comparison of the sensitivity of evaporative universal detectors and LC/MS in the HILIC and the reversed-phase HPLC modes.
Mitchell, C. R.; Bao, Y.; Benz, N. J.; Zhang, S.
J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 877 (32), 4133–4139.
2009 Dec 15
The successful implementation of Corona CAD technology in HPLC laboratories across a wide range of industries.
Ramsey, N. Chromatography 27 (Suppl. 2), 77–78.
2006
A new universal detector, Corona charged aerosol detection. Senda, M.; Fukushima, K.; Hashiguchi, K.; Matsumoto, T.; Gamache, P.; Waraska, J.; Asa, D.
Chromatography 27 (3), 119–124.
2006
A new universal detector, Corona charged aerosol detector and its applications.
Senda, M.; Kanedai, Y.; Fukushima, K.; Hirose, K.; Hashiguchi, K.; Matsumoto, T.
Chromatography 27 (Suppl. 1), 39–42.
2006
Evaluation of column bleed by using an ultraviolet and a charged aerosol detector coupled to a high-temperature liquid chromatographic system.
Teutenberg, T.; Tuerk, J.; Holzhauser, M.; Kiffmeyer, T. K.
J. Chromatogr., A. 1119 (1–2), 197–201.
2006 Jun 30
Review of operating principle and applications of the charged aerosol detector.
Vehovec, T.; Obreza, A. J. Chromatogr., A. 1217 (10), 1549–1556.
2010 Mar 5
Vervoort, N.; Daemen, D.; Török, G.
J. Chromatogr., A. 1189 (1–2), 92–100.
2008 May 2
Determination of relative response factors for chromatographic investigations using NMR spectrometry.
Webster, G. K.; Marsden, I.; Pommerening, C. A.; Tyrakowski, C. M.; Tobias, B.
J. Pharm. Biomed. Anal. 49 (5), 1261–1265.
2009 Jul 12
Pharmaceutical Polymers/ Surfactants
Title Authors Publication Publication Date
Development of analytical procedures to study changes in the composition of meat phospholipids caused by induced oxidation.
Cascone, A.; Eerola, S.; Ritieni, A.; Rizzo, A.
J. Chromatogr., A 1120 (1–2), 211–220.
2006 Jul 7
Evaporative light scattering and charged aerosol detector. Chaminade, P. Chapter 5. In Hyphenated and Alternative Methods of Detection in Chromatography, Chromatographic Science Series; Shalliker, A., Ed.; Taylor & Francis Group, LLC: Boca Raton, FL.; 145–160.
2012
Simple and efficient profiling of phospholipids in phospholipase D-modified soy lecithin by HPLC with charged aerosol detection.
Damnjanovic, J.; Nakano, H.; Iwasaki, Y.
J. Am. Oil Chem. Soc. 90 (7), 951–957.
2013 Jul
Discriminating olive and non-olive oils using HPLC-CAD and chemometrics.
de la Mata-Espinosa, P.; Bosque- Sendra, J. M.; Bro, R.; Cuadros- Rodríguez, L.
Anal. Bioanal. Chem. 399 (6), 2083–2092.
2011 Feb
Olive oil quantification of edible vegetable oil blends using triacylglycerols chromatographic fingerprints and chemometric tools.
de la Mata-Espinosa, P.; Bosque- Sendra, J. M.; Bro, R.; Cuadros- Rodríguez, L.
Talanta 85 (1), 177–182. 2011 Jul 15
Quantification of triacylglycerols in olive oils using HPLC-CAD. de la Mata-Espinosa, P.; Bosque- Sendra, J.; Cuadros-Rodriguez, L.
Food Analytical Methods 4 (4), 574–581.
2011 Dec
Pharmaceutical Polymers/ Surfactants
Quantification of pegylated phospholipids decorating polymeric microcapsules of perfluorooctyl bromide by reverse phase HPLC with a charged aerosol detector.
Díaz-López, R.; Libong, D.; Tsapis, N.; Fattal, E.; Chaminade, P.
J. Pharm. Biomed. Anal. 48 (3), 702–707.
2008 Nov 4
Squalene emulsions for parenteral vaccine and drug delivery. Fox, C. B. Molecules 14 (9), 3286– 3312.
2009 Sep 1
Interactions between parenteral lipid emulsions and container surfaces.
Gonyon, T.; Tomaso, A.; Kotha, P.; Owen, H.; Patel, D.; Carter, P.; Cronin, J.; Green, J.
PDA J. Pharm. Sci. and Tech. 67 (3), 247–254.
2013 May–Jun
Iwasaki, Y.; Masayama, A.; Mori, A.; Ikeda, C.; Nakano, H.
J. Chromatogr., A 1216 (32), 6077–6080.
2009 Aug 7
Determination of phospholipid and its degradation products in liposomes for injection by HPLC-charged aerosol detection (CAD).
Jiang, Q.; Yang, R.; Mei, X. Chinese Pharmaceutical Journal (Zhongguo Yaoxue Zazhi, Beijing, China) 42 (23), 1794–1796.
2007
Rapid quantification of yeast lipid using microwave-assisted total lipid extraction and HPLC-CAD.
Khoomrung, S.; Chumnanpuen, P.; Jansa-Ard, S.; Ståhlman, M.; Nookaew, I.; Borén, J.; Nielsen, J.
Anal. Chem. 85 (10), 4912– 4919.
2013 May 21
A new liquid chromatography method with charge aerosol detector (CAD) for the determination of phospholipid classes. Application to milk phospholipids.
Kieibowicz, G.; Micek, P.; Wawrzenczyk, C.
Talanta 105, 28–33. 2013 Feb 15
Title Authors Publication Publication Date
An LC method for the analysis of phosphatidylcholine hydrolysis products and its application to the monitoring of the acyl migration process.
Kiebowicz, G.; Smuga, D.; Gadkowski, W.; Chojnacka, A.; Wawrzenczyk, C.
Talanta 94, 22–29. 2012 May 30
Separation of acylglycerols, FAME and FFA in biodiesel by size exclusion chromatography.
Kittirattanapiboon, K.; Krisnangkurá, K.
2008 Mar 17
Quantitation of triacylglycerols from plant oils using charged aerosol detection with gradient compensation.
Lísa, M.; Lynen, F.; Holcapek, M.; Sandra, P.
J. Chromatogr., A. 1176 (1–2), 135–142.
2007 Dec 28
Quantitative study of the stratum corneum lipid classes by normal phase liquid chromatography: comparison between two universal detectors.
Merle, C.; Laugel, C.; Chaminade, P.; Baillet-Guffroy, A.
J. Liq. Chromatogr. Relat. Technol. 33, 629–644.
2010 Mar
The analysis of lipids via HPLC with a charged aerosol detector.
Moreau, R. A. Lipids 41 (7), 727–34. 2006 Jul
Lipid analysis via HPLC with a charged aerosol detector. Moreau, R. A. Lipid Technol. 21 (8–9), 191–194.
2009 Oct 23
Extraction and analysis of food lipids. Moreau, R. A.; Winkler-Moser, J. K.
Chapter 6. In Methods of Analysis of Food Components and Additives, Second Edition; Ötles, S., Ed.; Taylor & Francis Group, LLC: Boca Raton, FL.; 115–134.
2011 Nov
Aerosol based detectors for the investigation of phospholipid hydrolysis in a pharmaceutical suspension formulation.
Nair, L.; Werling, J. J. Pharm. Biomed. Anal. 49 (1), 95–99.
2009 Jan 15
Pharmaceutical Polymers/ Surfactants
Structure/function relationships of adipose phospholipase A2 containing a cys-his-his catalytic triad.
Pang, X. Y.; Cao, J.; Addington, L.; Lovell, S.; Battaile, K. P.; Zhang, Rao, J. L.; Dennis, E. A.; Moise, A. R.
J. Biol. Chem. 287 (42), 35260–35274.
2012 Oct 12
Simultaneous assessment of lipid classes and bile acids in human intestinal fluid by solid-phase extraction and HPLC methods.
Persson, E.; Löfgren, L.; Hansson, G.; Abrahamsson, B.; Lennernäs, H.; Nilsson, R.
J. Lipid Res. 48 (1), 242– 251.
2007 Jan
The use of charged aerosol detection with HPLC for the measurement of lipids.
Plante, M.; Bailey, B.; Acworth, I. Methods Mol. Biol. (Totowa, NJ, U.S.) 579, 469–482.
2009
Comparison between charged aerosol detection and light scattering detection for the analysis of Leishmania membrane phospholipids.
Ramos, R. G.; Libong, D.; Rakotomanga, M.; Gaudin, K.; Loiseau, P. M.; Chaminade, P.
J. Chromatogr., A. 1209 (1–2), 88–94.
2008 Oct 31
Ruiz-Samblás, C.; Arrebola- Pascual, C.; Tres, A.; van Ruth, S.; Cuadros-Rodríguez, L.
Talanta. 116, 788–793. 2013 Nov 15
Simple and precise detection of lipid compounds present within liposomal formulations using a charged aerosol detector.
Schönherr, C.; Touchene, S.; Wilser, G.; Peschka-Süss, R.; Francese, G.
J. Chromatogr., A. 1216 (5), 781–786.
2009 Jan 30
Determination of intralumenal individual bile acids by HPLC with charged aerosol detection.
Vertzoni, M.; Archontaki, H.; Reppas, C.
J. Lipid Res. 49 (12), 2690–2695.
2008 Dec
Neurolipids and the use of a charged aerosol detector. Waraska, J.; Acworth, I. Am. Biotechnol. Lab. 26 (1), 12–13.
2008
Pharmaceutical Polymers/ Surfactants
Improving the universal response of evaporative light scattering detection by mobile phase compensation.
de Villiers, A.; Górecki, T.; Lynen, F.; Szucs, R.; Sandra, P.
J. Chromatogr., A 1161 (1–2), 183–191.
2007 Aug 17
Díaz-López, R.; Libong, D.; Tsapis, N.; Fattal, E.; Chaminade, P.
J. Pharm. Biomed. Anal. 48 (3), 702–707.
2008 Nov 4
Phospholipid decoration of microcapsules containing perfluorooctyl bromide used as ultrasound contrast agents.
Díaz-López, R.; Tsapis, N.; Libong, D.; Chaminade, P.; Connan, C.; Chehimi, M. M.; Berti, R.; Taulier, N.; Urbach, W.; Nicolas, V.; Fattal, E.
Biomaterials 30 (8), 1462– 1472.
2009 Mar
Aerosol-based detectors for liquid chromatography: Do they have a role in bioanalysis?
Dixon, R. W. Bioanalysis 1 (8), 1389– 1392.
2009 Nov
Górecki, T.; Lynen, F.; Szucs, R.; Sandra, P.
Anal. Chem. 78 (9), 3186– 3192.
2006 May 1
2007 Nov 2
Characterization of an endoglucanase belonging to a new subfamily of glycoside hydrolase family 45 of the basidiomycete Phanerochaete chrysosporium.
Igarashi, K.; Ishida, T.; Hori, C.; Samejima, M.
Appl. Environ. Microbiol. 74 (18), 5628–5634.
2008 Sep
Serial coupling of reversed-phase and hydrophilic interaction liquid chromatography to broaden the elution window for the analysis of pharmaceutical compounds.
Louw, S.; Pereira, A. S.; Lynen, F.; Hanna-Brown, M.; Sandra, P.
J. Chromatogr., A 1208 (1- 2), 90–94.
2008 Oct 24
Determination of parabens in cosmetic products using multi- walled carbon nanotubes as solid phase extraction sorbent and corona-charged aerosol detection system.
Márquez-Sillero, I.; Aguilera- Herrador, E.; Cárdenas, S.; Valcárcel, M.
J. Chromatogr., A. 1217 (1), 1–6.
2010 Jan 1
Pharmaceutical Polymers/ Surfactants
Bioactive contaminants leach from disposable laboratory plasticware.
McDonald, G. R.; Hudson, A. L.; Dunn, S. M. J.; You, H.; Baker, G. B.; Whittal, R. M.; Martin, J. W.; Jha, A.; Edmondson, D. E.; Holt, A.
Science 322 (5903), 917. 2008 Nov 7
Enzymatic reaction coupled with flow-injection analysis with charged aerosol, coulometric, or amperometric detection for estimation of contamination of the environment by pesticides.
Mikelova, R.; Prokop, Z.; Stejskal, K.; Adam, V.; Beklova, M.; Trnkova, L.; et al.
Chromatographia 67 (Suppl. 1), 47–53.
2008 May
Enzymatic reaction coupled with flow-injection analysis with charged aerosol, coulometric, or amperometric detection for estimation of contamination of the environment by pesticides.
Mikelova, R.; Prokop, Z.; Stejskal, K.; Adam, V.; Beklova, M.; Trnkova, L.; Kulichova, B.; Horna, A.; Chaloupkova, R.; Damborsky, J.; Kizek, R.
Chromatographia 67 (1), 47–53.
2008 May 1
Implementation of charged aerosol detection in routine reversed phase liquid chromatography methods.
Reilly, J.; Everatt, B.; Aldcroft, C. J. Liq. Chromatogr. Relat. Technol. 31, 3132–3142.
2008
The corona charged aerosol detector for liquid chromatography and high field asymmetric waveform ion mobility spectrometry combined with liquid chromatography/ mass spectrometry and gas chromatography.
Sherma, J.; Larkin, J. D.; Larkin, F. H.
J. AOAC Int. 89 (1), 15A–19A.
2006 Jan–Feb
Pharmaceutical Polymers/ Surfactants
Validated HPLC method for the quantitative analysis of a 4-methanesulfonyl-piperidine hydrochloride salt.
Soman, A.; Jerfy, M.; Swanek, F. J. Liq. Chromatogr. Relat. Technol. 32 (7), 1000– 1009.
2009 Mar 9
Stojanovic, A.; Lämmerhofer, M.; Kogelnig, D.; Schiesel, S.; Sturm, M.; Galanski, M.; Krachler, R.; Keppler, B. K.; Lindner, W.
J. Chromatogr., A. 1209 (1–2), 179–187.
2008 Oct 31
Determination of relative response factors of impurities in paclitaxel with high performance liquid chromatography equipped with ultraviolet and charged aerosol detectors.
Sun, P.; Wang, X.; Alquier, L.; Maryanoff, C. A.
J. Chromatogr., A 1177 (1), 87–91.
2008 Jan 4
Quantitative comparison of a corona-charged aerosol detector and an evaporative light-scattering detector for the analysis of a synthetic polymer by supercritical fluid chromatography.
Takahashi, K.; Kinugasa, S.; Senda, M.; Kimizuka, K.; Fukushima, K.; Matsumoto, T.; Shibata, Y.; Christensen, J.
J. Chromatogr., A 1193 (1–2), 151–155.
2008 Jun 6
Evaluation of column bleed by using an ultraviolet and a charged aerosol detector coupled to a high-temperature liquid chromatographic system.
Teutenberg, T.; Tuerk, J.; Holzhauser, M.; Kiffmeyer, T. K.
J. Chromatogr., A 1119 (1–2), 197–201.
2006 Jun 30
1,2-α-L-Fucosynthase: A glycosynthase derived from an inverting a-glycosidase with an unusual reaction mechanism.
Wada, J.; Honda, Y.; Nagae, M.; Kato, R.; Wakatsuki, S.; Katayama, T.; Taniguchi, H.; Kumagai, H.; Kitaoka, M.; Yamamoto, K.
FEBS Lett. 582 (27), 3739– 3743.
2008 Nov 12
HPLC determinations of enantiomeric ratios. Wipf, P.; Werner, S.; Twining, L. A.; Kendall, C.
Chirality 19 (1), 5–9. 2007 Jan
Introduction Antibiotics Carbohydrates Food/Nutrition General Lipids Miscellaneous Natural Products/ Supplements
Pharmaceutical Polymers/ Surfactants
Pharmaceutical Polymers/ Surfactants
Aqueous extract of Astragali Radix induces human natriuresis through enhancement of renal response to atrial natriuretic peptide.
Ai, P.; Yong, G.; Dingkun, G.; Qiuyu, Z.; Kaiyuan, Z.; Shanyan, L.
J. Ethnopharmacol. 116 (13), 413–421.
2008 Mar 28
Recent methodology in ginseng analysis. Baek, S.; Bae, O.; Park, J. J. Ginseng Res. 36 (2), 119–134.
2012 Apr
Sensitive determination of saponins in radix et rhizoma notoginseng by charged aerosol detector coupled with HPLC.
Bai, C.; Han, S.; Chai, X.; Jiang, Y.; Li, P.; Tu, P.
J. Liq. Chromatogr. Relat. Technol. 32 (2), 242–260.
2010 Aug 27
The real nature of the indole alkaloids in Cortinarius infractus: Evaluation of artifact formation through solvent extraction method development.
Brondz, I.; Ekeberg, D.; Høiland, K.; Bell, D.; Annino, A.
J. Chromatogr., A 1148 (1), 1–7.
2007 Apr 27
Brondz, I.; Høiland, K. Trends Chromatogr. 4, 79–87.
2008
Utilization of RP-HPLC fingerprinting analysis for the identification of diterpene glycosides from Stevia rebaudiana.
Chaturvedula, V.; Prakash, I. Int. J. Res. Phytochem. Pharmacol. 1 (2), 88–92.
2011 Jun 9
Acid and alkaline hydrolysis studies of stevioside and rebaudioside A.
Chaturvedula, V.; Prakash, I. J. Appl. Pharm. Sci. 1 (8), 104–108.
2011 Oct
Spectral analysis and chemical studies of the sweet constituent, rebaudioside A.
Chaturvedula, V.; Prakash, I. Eur. J. Med. Plants 2 (1), 57–65.
2012 Feb
Photostability of rebaudioside A and stevioside in beverages. Clos, J. F.; DuBois, G. E.; Prakash, I.
J. Agric. Food Chem. 56 (18), 8507–8513.
2008 Sep 24
Comparison between evaporative light scattering detection and charged aerosol detection for the analysis of saikosaponins.
Eom, H. Y.; Park, S. Y.; Kim, M. K.; Suh, J. H.; Yeom, H.; Min, J. W.; Kim, U.; Lee, J.; Youm, J. R.; Han, S. B.
J. Chromatogr., A. 1217 (26), 4347–4354.
2010 Jun 25
HPLC with charged aerosol detection for the measurement of natural products.
Fukushima, K.; Kanedai, Y.; Hirose, K.; Matsumoto, T.; Hashiguchi, K.; Senda, M.; et al.
Chromatography 27 (Suppl. 1), 83–86.
2006
Pharmaceutical Polymers/ Surfactants
Development and validation of HPLC-DAD-CAD-MS3 method for qualitative and quantitative standardization of polyphenols in Agrimoniae eupatoriae herba (Ph. Eur).
Granica, S.; Krupa, K.; Kebowska, A.; Kiss, A. K.
J. Pharm. Biomed. Anal. 86, 112–122.
2013 Dec
A new application of charged aerosol detection in liquid chromatography for the simultaneous determination of polar and less polar ginsenosides in ginseng products.
Jia, S.; Li, J.; Yunusova, N.; Park, J. H.; Kwon, S. W.; Lee, J.
Phytochem. Anal. 24 (4), 374–380.
2013 Jul–Aug
Analysis of terpene lactones in a Ginkgo leaf extract by high- performance liquid chromatography using charged aerosol detection.
Kakigi, Y.; Mochizuki, N.; Icho, T.; Hakamatsuka, T.; Goda, Y.
Biosci., Biotechnol., Biochem. 74 (3), 590–594.
2010
Linear aglycones are the substrates for glycosyltransferase DesVII in methymycin biosynthesis: analysis and implications.
Kao, C.; Borisova, S.; Kim, H.; Liu, H.
J. Am. Chem. Soc. 128 (17), 5606–5607.
2006 May 3
Certification of a pure reference material for the ginsenoside Rg1.
Kim, D.; Chang, J.; Sohn, H.; Cho, B.; Ko, S.; Nho, K.; Jang, D.; Lee, S.
Accredit. Qual. Assur. 15 (2), 81–87.
2009 Sep
Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla.
Kim, S. H.; Kim, H. K.; Yang, E. S.; Lee, K. Y.; Kim, S. D.; Kim, Y. C.; Sung, S. H.
Sep. Purif. Technol. 71 (2), 168–172.
2010
Production of surfactin and iturin by Bacillus licheniformis N1 responsible for plant disease control activity.
Kong, H. G.; Kim, J. C.; Choi, G. J.; Lee, K. Y.; Kim, H. J.; Hwang, E. C.; Moon, B. J.; Lee, S. W.
Plant Pathol. J. 26 (2), 170–177.
2010
Photodiode array (PDA) and other detection methods in HPLC of plant metabolites.
Markowski, W.; Waksmundzka- Hajnos, M.
Chapter 13. In High Performance Liquid Chromatography in Phytochemical Analysis, Chromatographic Science Series, Markowski, W., Sherma, J., Eds.; Taylor & Francis Group, LLC: Boca Raton, FL; 331–350.
2010 Nov
Natural Products/Supplements
High-performance liquid chromatography analysis of plant saponins: An update 2005-2010.
Negi, J. S.; Singh, P.; Pant, G. J.; Rawat, M. S.
Pharmacogn. Rev. 5 (10), 155–158.
2011 Jul
Poplawska, M.; Blazewicz, A.; Bukowinska, K.; Fijalek, Z.
J. Pharm. Biomed. Anal. 84, 232–243.
2013 Oct
Isolation and analysis of ginseng: advances and challenges. Qi, L.; Wang, C.; Yuan, C. Nat. Prod. Rep. 28 (3), 467–495.
2011 Mar
Sasaki, E.; Ogasawara, Y.; Liu, H. W.
J. Am. Chem. Soc. 132 (21), 7405–7417.
2010 Jun 2
Rapid purification method for fumonisin B1 using centrifugal partition chromatography.
Szekeres, A.; Lorántfy, L.; Bencsik, O.; Kecskeméti, A.; Szécsi, Á.; Mesterházy, Á.; Vágvölgyi, C.
Food Addit. Contam. 30 (1), 147–155.
2013
Performance evaluation of charged aerosol and evaporative light scattering detection for the determination of ginsenosides by LC.
Wang, L.; He, W. S.; Yan, H. X.; Jiang, Y.; Bi, K. S.; Tu, P. F.
Chromatographia 70 (3–4), 603–608.
2009 Aug
HPLC in natural product analysis: The detection issue. Wolfender, J. L. Planta Med. 75 (07), 719– 734.
2009 Jun
Simultaneous determination of triterpenoid saponins from pulsatilla koreana using high performance liquid chromatography coupled with a charged aerosol detector (HPLC-CAD).
Yeom, H.; Suh, J. H.; Youm, J. R.; Han, S. B.
Bull. Korean Chem. Soc. 31 (5), 1159–1164.
2010
Pharmaceutical Polymers/ Surfactants
Pharmaceutical Polymers/ Surfactants
Charged aerosol detection in pharmaceutical analysis. Almeling, S.; Ilko, D.; Holzgrabe, U.
J. Pharm. Biomed. Anal. 69, 50–63.
2012 Oct
Quantitation of acetol in common pharmaceutical excipients using LC–MS.
Beilin, E.; Baker, L. J.; Culbert, P.; Toltl, N. P.
J. Pharm. Biomed. Anal. 46 (2), 316–321.
2008 Jan 22
Determination of pancuronium and its impurities in pharmaceutical preparation by LC with charged aerosol detection.
Bazewicz, A.; Fijaek, Z.; Sarna, K.; Warowna-Grzeskiewicz, M.
Chromatographia 72 (1–2), 183–186.
2010 Jul
Bazewicz, A.; Fijaek, Z.; Warowna-Grzeskiewicz, M.; Jadach, M.
J. Chromatogr., A. 1217 (8), 1266–1272.
2010 Feb 19
Anal. Chem. 79 (6), 2472– 2482.
2007 Mar 15
Hydrophilic interaction chromatography with aerosol-based detectors (ELSD, CAD, NQAD) for polar compounds lacking a UV chromophore in an intravenous formulation.
Cintrón, J. M.; Risley, D. S. J. Pharm. Biomed. Anal. 78–79, 14–18.
2013 May 5
Crafts, C.; Bailey, B.; Gamache, P.; Liu, X.; Acworth, I.
Chapter 10. In Applications of Ion Chromatography in the Analysis of Pharmaceutical and Biological Products; Bhattacharyya, L., Rohrer, J. S., Eds.; Wiley: New Jersey, 221–236.
2012 Mar
Pharmaceutical Polymers/ Surfactants
Title Authors Publication Publication Date
Evaluation of methods for the simultaneous analysis of cations and anions using HPLC with charged aerosol detection and a zwitterionic stationary phase.
Crafts, C.; Bailey, B.; Plante, M.; Acworth, I.
J. Chromatogr. Sci. 47 (7), 534–539.
2009 Aug
HILIC methods in pharmaceutical analysis. Dejaegher, B.; Heyden, Y. J. Sep. Sci. 33 (6–7), 698– 715.
2010 Mar
Díaz-López, R.; Libong, D.; Tsapis, N.; Fattal, E.; Chaminade, P.
J. Pharm. Biomed. Anal. 48 (3), 702–707.
2008 Nov 4
Fireman, J.; Carter, D.; Wallace, M.
Am. Biotechnol. Lab. 25, 18.
2007
Forsatz, B.; Snow, N. LC-GC North America 25 (9), 960.
2007 Sep 1
Squalene emulsions for parenteral vaccine and drug delivery. Fox, C. B. Molecules 14 (9), 3286– 3312.
2009 Sep 1
Monitoring the effects of component structure and source on formulation stability and adjuvant activity of oil-in-water emulsions.
Fox, C. B.; Anderson, R. C.; Dutill, T. S.; Goto, Y.; Reed, S. G.; Vedvick, T. S.
Colloids Surf., B 65 (1), 98–105.
2008 Aug 1
Effects on immunogenicity by formulations of emulsion-based adjuvants for malaria vaccines.
Fox, C. B.; Baldwin, S. L.; Vedvick, T. S.; Angov, E.; Reed, S. G.
Clin. Vaccine Immunol. 19 (10), 1633–1640.
2012 Oct
Gaberc-Porekar, V.; Zore, I.; Podobnik, B.; Menart, V.
Curr. Opin. Drug Discovery Dev. 11 (2), 242–250.
2008 Mar
Gorecki, T.; Lynen, F.; Szucs, R.; Sandra, P.
Anal. Chem. 78 (9), 3186– 3192.
2006 May 1
Pharmaceutical Polymers/ Surfactants
Title Authors Publication Publication Date
Control of impurities in L-aspartic acid and L-alanine by high- performance liquid chromatography coupled with a corona charged aerosol detector.
Holzgrabe, U.; Nap, C. J.; Almeling, S.
J. Chromatogr., A. 1217 (3), 294–301.
2010 Jan 15
Alternatives to amino acid analysis for the purity control of pharmaceutical grade L-alanine.
Holzgrabe, U.; Nap, C. J.; Beyer, T.; Almeling, S.
J. Sep. Sci. 33 (16), 2402– 2410.
2010 Aug
Development of a reversed-phase HPLC impurity method for a UV variable isomeric mixture of a CRF drug substance intermediate with the assistance of Corona CAD.
Huang, Z.; Neverovitch, M.; Lozano, R.; Tattersall, P.; Ruan, J.
J. Pharm. Innov. 6 (2), 115–123.
2011 Jun
Determination of inorganic pharmaceutical counterions using hydrophilic interaction chromatography coupled with a Corona CAD detector.
Huang, Z.; Richards, M. A.; Zha, Y.; Francis, R.; Lozano, R.; Ruan, J.
J. Pharm. Biomed. Anal. 50 (5), 809–814.
2009 Dec 5
Forced degradation and impurity profiling: Recent trends in analytical perspectives.
Jain, D.; Basniwal, P. K. J. Pharm. Biomed. Anal. 86, 11–35.
2013 Jul 31
Non-derivatization method for the determination of gabapentin in pharmaceutical formulations, rat serum and rat urine using high performance liquid chromatography coupled with charged aerosol detection.
Jia, S.; Lee, H.S.; Choi, M.J.; Sung, S.H.; Han, S.B.; Park, J.H.; Hong, S.S.; Kwon, S.W.; Lee, J.
Curr. Anal. Chem. 8 (1), 159–167.
2012
Comparison of two aerosol-based detectors for the analysis of gabapentin in pharmaceutical formulations by hydrophilic interaction chromatography.
Jia, S.; Park, J. H.; Lee, J.; Kwon, S. W.
Talanta 85 (5), 2301–2306. 2011 Oct 15
Linear aglycones are the substrates for glycosyltransferase DesVII in methymycin biosynthesis: analysis and implications.
Kao, C. L.; Borisova, S. A.; Kim, H. J.; Liu, H. W.
J. Am. Chem. Soc. 128 (17), 5606–5607.
2006 May 3
Ion chromatography coupled to universal detectors for the analysis of pharmaceutically-related anions.
Karu, N.; Hutchinson, J. P.; Dicinoski, G. W.; Hanna-Brown, M.; Haddad, P. R.
Sep. Sci. 4 (14), 14–19. 2012
Pharmaceutical Polymers/ Surfactants
Determination of pharmaceutically related compounds by suppressed ion chromatography: IV. Interfacing ion chromatography with universal detectors.
Karu, N.; Hutchinson, J. P.; Dicinoski, G. W.; Hanna-Brown, M.; Srinivasan, K.; Pohl, C. A.; Haddad, P. R.
J. Chromatogr., A. 1253, 44–51.
2012 Aug 31
PEGylation of cholecystokinin prolongs its anorectic effect in rats.
León-Tamariz, F.; Verbaeys, I.; Van Boven, M.; De Cuyper, M.; Buyse, J.; Clynen, E.; Cokelaere, M.
Peptides 28 (5), 1003– 1011.
2007 May
Liu, X. K.; Fang, J. B.; Cauchon, N.; Zhou, P.
J. Pharm. Biomed. Anal. 46 (4), 639–644.
2008 Mar 13
Evaluation of charged aerosol detection (CAD) as a complementary technique for high-throughput LC-MS-UV- ELSD analysis of drug discovery screening libraries.
Loughlin, J.; Phan, H.; Wan, M.; Guo, S.; May, K.; Lin, B.
American Laboratory 39, 24.
Serial coupling of reversed-phase and hydrophilic interaction liquid chromatography to broaden the elution window for the analysis of pharmaceutical compounds.
Louw, S.; Pereira, A.; Lynen, F.; Hanna-Brown, M.; Sandra, P.
J. Chromatogr., A. 1208 (1–2), 90–94.
2008 Oct 24
McCarthy, R.; Gamache, P.; Asa, D.
G.I.T. Laboratory Journal Europe 9, (4), 26–27.
2005
Aerosol based detectors for the investigation of phospholipid hydrolysis in a pharmaceutical suspension formulation.
Nair, L. M.; Werling, J. O. J. Pharm. Biomed. Anal. 49 (1), 95–99.
2009 Jan 15
Comparison of UV and charged aerosol detection approach in pharmaceutical analysis of statins.
Nováková, L.; Lopéz, S. A.; Solichová, D.; Satínský, D.; Kulichová, B.; Horna, A.; Solich, P.
Talanta 78 (3), 834–839. 2009 May 15
Novel MS solutions inspired by MIST. Ramanathan, R.; Josephs, J. L.; Jemal, M.; Arnold, M.; Humphreys, W. G.
Bioanalysis 2 (7), 1291– 1313.
2010 Jul
Pharmaceutical Polymers/ Surfactants
Title Authors Publication Publication Date
The effect of composting on the degradation of a veterinary pharmaceutical.
Ramaswamy, J.; Prasher, S. O.; Patel, R. M.; Hussain, S. A.; Barrington, S. F.
Bioresour Technol. 101 (7), 2294–2299.
2010 Apr
Implementation of charged aerosol detection in routine reversed phase liquid chromatography methods.
Reilly, J.; Everatt, B.; Aldcroft, C. J. Liq. Chromatogr. Relat. Technol. 31 (20), 3132– 3142.
2008 Oct 22
Rystov, L.; Chadwick, R.; Krock, K.; Wang, T.
J. Pharm. Biomed. Anal. 56 (5), 887–894.
2011 Dec 15
Comparison of ultraviolet detection, evaporative light scattering detection and charged aerosol detection methods for liquid-chromatographic determination of anti-diabetic drugs.
Shaodong, J.; Lee, W. J.; Ee, J. W.; Park, J. H.; Kwon, S. W.; Lee, J.
J. Pharm. Biomed. Anal. 51 (4), 973–978.
2010 Mar 11
Applications of the charged aerosol detector in compound management.
Sinclair, I.; Charles, I. J. Biomol. Screening 14 (5), 531–537.
2009 Jun
Charged aerosol detection: Factors for consideration in its use as a generic quantitative detector.
Sinclair, I.; Gallagher, R. Chromatography Today 1 (3), 5–9.
2008 Jun
Determination of relative response factors of impurities in paclitaxel with high performance liquid chromatography equipped with ultraviolet and charged aerosol detectors.
Sun, P.; Wang, X.; Alquier, L.; Maryanoff, C.
J. Chromatogr., A. 1177 (1), 87–91.
2008 Jan 4
Vervoort, N.; Daemen, D.; Török, G.
J. Chromatogr., A 1189 (1–2), 92–100.
2008 May 2
Neurolipids and the use of a charged aerosol detector. Waraska, J.; Acworth, I. N. American Biotech. Lab. 26 (1), 12–13.
2008
HPLC determinations of enantiomeric ratios. Wipf, P.; Werner, S.; Twining, L. A.; Kendall, C.
Chirality 19 (1), 5–9. 2007 Jan
Biosynthesis of fosfomycin, re-examination and re- confirmation of a unique Fe(II)- and NAD(P)H-dependent epoxidation reaction.
Yan, F.; Munos, J. W.; Liu, P.; Liu, H. W.
Biochemistry 45 (38), 11473–11481.
2006 Sep 26
A new approach to threshold evaluation and quantitation of unknown extractables and leachables using HPLC/CAD
Yu, X., Zdravkovic, S., Wood, D.; Li, C., Cheng, Y.; Ding, X.
Drug Delivery Technol. 9 (3), 50–55.
2009
Genotoxic impurities: A quantitative approach. Yuabova, Z. Y.; Holschlag, D. R.; Rodriguez, S. A.; Qin, C.; Papov, V. V.; Qiu, F.; McCaffrey, J. F.; Norwood, D. L.
J. Liq. Chromatogr. Relat. Technol. 31, 2318–2330.
2008 Aug 7
Advances in HPLC detection—towards universal detection. Zhang, B.; Li, X.; Yan, B. Anal. Bioanal. Chem. 390 (1), 299–301.
2008 Jan
Analysis of pharmaceutical impurities using multi-heart cutting 2D LC coupled with UV-charged aerosol MS detection.
Zhang, K.; Li, Y.; Tsang, M.; Chetwyn, N. P.
J. Sep. Sci. 36 (18), 2986– 2992.
2013 Sep
Pharmaceutical Polymers/ Surfactants
Pharmaceutical Polymers/ Surfactants
Quantitation of acetol in common pharmaceutical excipients using LC–MS.
Beilin, E.; Baker, L. J.; Culbert, P.; Toltl, N. P.
J. Pharm. Biomed. Anal. 46 (2), 316–321.
2008 Jan 22
Christiansen, A.; Backensfeld, T.; Kühn, S.; Weitschies, W.
J. Pharm. Sci. 100 (5), 1773–1782.
2011 May
Stability of the non-ionic surfactant polysorbate 80 investigated by HPLC-MS and charged aerosol detector.
Christiansen, A.; Backensfeld, T.; Kühn, S.; Weitschies, W.
Pharmazie 66 (9), 666–671. 2011 Sep
Investigating the stability of the nonionic surfactants tocopheryl polyethylene glycol succinate and sucrose laurate by HPLC–MS, DAD, and CAD.
Christiansen, A.; Backensfeld, T.; Kühn, S.; Weitschies, W.
J. Pharm. Sci. 100 (5), 1773–1782.
2011 May
Fast and sensitive determination of Polysorbate 80 in solutions containing proteins.
Fekete, S.; Ganzler, K.; Fekete, J. J. Pharm. Biomed. Anal. 52 (5), 672–9.
2010 Sep 5
HPLC with charged aerosol detection for the measurement of different non-ionic surfactants.
Fukushima, K.; Matsumoto, T.; Hashiguchi, K.; Senda, M.; Carreiro, D.; Asa, D.; et al.
Chromatography 27 (Suppl. 2), 139–142.
2006
Greiderer, A.; Steeneken, L.; Aalbers, T.; Vivó-Truyols, G.; Schoenmakers, P.
J. Chromatogr., A. 1218 (34), 5787–5793.
2011 Aug 26
Size exclusion chromatography with Corona charged aerosol detector for the analysis of polyethylene glycol polymer.
Kou, D.; Manius, G.; Zhan, S.; Chokshi, H. P.
J. Chromatogr., A. 1216 (28), 5424–5428.
2009 Jul 10
Analysis of polysorbate 80 using fast HPLC and charged aerosol detection.
Lobback, C.; Backensfeild, T.; Funke, A.; Weltschies, W.
Pharm. Technol. 34 (5), 48. 2010 May
Quantitative determination of nonionic surfactants with CAD. Lobback, C.; Backensfeld, T.; Funke, A.; Weitschies, W.
Chromatography Techniques, 18.
Drug Discovery Dev. 10 (11, special section), 18.
2007 Nov
Analysis of quaternary ammonium and phosphonium ionic liquids by reversed-phase high performance liquid chromatography with charged aerosol detection and unified calibration.
Stojanovic, A.; Lämmerhofer, M.; Kogelnig, D.; Schiesel, S.; Sturm, M.; Galanski, M.; Krachler, R.; Keppler, B. K.; Lindner, W.
J. Chromatogr., A 1209 (1–2), 179–187.
2008 Oct 31
Quantitative comparison of a corona-charged aerosol detector and an evaporative light-scattering detector for the analysis of a synthetic polymer by supercritical fluid chromatography.
Takahashi, K.; Kinugasa, S.; Senda, M.; Kimizuka, K.; Fukushima, K.; Matsumoto, T.; Shibata, Y.; Christensen, J.
J. Chromatogr., A. 1193 (1–2), 151–155.
2008 Jun 6
SEC assay for polyvinylsulfonic impurities in 2-(N-morpholino) ethanesulfonic acid using a charged aerosol detector.
Zhang, T.; Hewitt, D.; Kao, Y. H. Chromatographia 72 (1–2), 145–149.
2010 Jul
Pharmaceutical Polymers/ Surfactants
Pharmaceutical Polymers/ Surfactants
Evaluation of charged aerosol detector for purity assessment of protein.
Wang, R.; Wang, X.; Paulino, J.; Alquier, L.
J. Chromatogr., A. 1283, 116–121.
2013 Mar 29
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both routine and complex analyses. This bibliography
is designed to readily show the analytical capabilities of
charged aerosol detection and highlights the breadth
and scope of the different analytical methods found
in the literature.
For ease of use, the document is divided into different
categories based on either the family of analytes being
measured (e.g., carbohydrates, lipids, surfactants)
or the relevant market place (e.g., Food/Nutrition,
Pharmaceutical) being served. Each publication is
hyperlinked so that you can obtain more information
about the article including analytes being measured and
sample matrices.
Pharmaceutical Polymers/ Surfactants
ideal results. Often, one analyte responds more strongly
than another, or may not respond at all. UV absorbance
detection requires that the molecule contain a chromo-
phore and Inter-analyte response can vary greatly
depending upon the nature of the chromophore present.
Refractive index detection cannot be used with gradient
elution and is temperature sensitive.
Mass spectrometry can only measure compounds that
will form gas-phase ions.
analyte response and complex, non-linear calibration
curves.
What is most desired in a universal detector is the
ability to accurately measure a wide range of analytes
with consistent response. Charged aerosol detection
can measure any non-volatile and most semi-volatile
analytes at sub-nanogram levels and does not require
a compound to contain a chromophore or be able
to ionize. Variance in inter-analyte relative response
is minimal whether analyzing small molecules or
proteins. The technique is fully compatible with gradient
chromatography.
Introduction
Introduction Antibiotics Carbohydrates Food/Nutrition General Lipids Miscellaneous Natural Products/ Supplements
Pharmaceutical Polymers/ Surfactants
the column. Large droplets exit the detector to waste.
Selected smaller droplets enter the evaporation tube and
form particles once the solvent is evaporated. Particles
then enter a reaction chamber where they collide with
ionized gas formed when nitrogen is passed over a corona
wire. Charge is transferred from the ionized gas to the
analyte particles. Once unreacted ionized gas is removed
by an ion trap, the charge on the particle is measured by
a sensitive electrometer. The response of the detector
is directly related to the mass of the analyte entering the
detector. An increase in the amount of an analyte eluting
from the column leads to an increase in the size of the
particles being formed. Larger particles can accommodate
more charge, resulting in a higher response from the
detector. As long as the analyte will form a particle it will be
measured by charged aerosol detection, independent of
its chemical structure.
without the need for complex detector optimization and
has the flexibility to measure a broad range of analytes in
many different matrices. The Thermo Scientific™ Dionex™
Corona™ Veo™ charged aerosol detector is HPLC/UHPLC
compatible and with its extended flow rate range, can
be used with capillary, microbore, and analytical-scale
columns. The detector improves on all the benefits of
charged aerosol detection in a design perfectly matched to
your laboratory’s needs.
How the Technology Works
Pharmaceutical Polymers/ Surfactants
Pharmaceutical Polymers/ Surfactants
Title Authors Publication Publication Date
Production of surfactin and iturin by Bacillus licheniformis N1 responsible for plant disease control activity.
Gi Kong, H.; Kim, J.; Choi, G.; Lee, K.; Kim, H.; Hwang, E.; Moon, B.; Lee, S.
Plant Pathol. J. (Seoul, Repub. Korea) 26 (2), 170–177.
2010 Mar 21
J. Pharm. Biomed. Anal. 56 (2), 271–279.
2011 Sep 10
The effect of composting on the degradation of a veterinary pharmaceutical.
Jayashree, R.; Prasher, S.; Patel, R.; Hussain, S.; Barrington, S.
Bioresour. Technol. 101 (7), 2294–2299.
2010 Apr
Effect of soil pH on sorption of salinomycin in clay and sandy soils.
Jayashree, R.; Prasher, S.; Rajvinder, K.; Patel, R.
Afr. J. Environ. Sci. Technol. 5 (9), 661–667.
2011 Sep
Combined application of dispersive liquid-liquid microextraction based on the solidification of floating organic droplets and charged aerosol detection for the simple and sensitive quantification of macrolide antibiotics in human urine.
Jia, S.; Li, J.; Park, S. R.; Ryu, Y.; Park, I. H.; Park, J. H.; Hong, S. S.; Kwon, S. W.; Lee, J.
J. Pharm. Biomed. Anal. 86C, 204–213.
2013 Dec
Development and validation of a RP-HPLC method for the estimation of netilmicin sulfate and its related substances using charged aerosol detection.
Joseph, A.; Patel, S.; Rustum, A. J. Chromatogr. Sci. 48 (7), 607–612.
2010 Aug
Development and validation of a RP-HPLC method for the determination of gentamicin sulfate and its related substances in a pharmaceutical cream using a short pentafluorophenyl column and a charged aerosol detector.
Joseph, A.; Rustum, A. J. Pharm. Biomed. Anal. 51 (3), 521–531.
2010 Feb 5
Polyketide analysis using mass spectrometry, evaporative light scattering, and charged aerosol detector systems.
Pistorino, M.; Pfeifer, B. A. Anal. Bioanal. Chem. 390 (4), 1189–1193.
2008 Feb
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2010 Dec
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2013 Mar 25
Biosynthesis of fosfomycin, re-examination and re- confirmation of a unique Fe (II) and NAD (P) H-dependent epoxidation reaction.
Yan, F.; Munos, J.; Liu, P.; Liu, H. Biochemistry 45 (38), 11473–11481.
2006 Sep 26
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Carbohydrate and oligosaccharide analysis with a universal HPLC detector.
Asa, D. American Laboratory 38, 16.
2006
Determination of levoglucosan in atmospheric aerosols using high performance liquid chromatography with aerosol charge detection.
Dixon, R. W.; Baltzell, G. J. Chromatogr., A. 1109 (2), 214–221.
2006 Mar 24
Composition of structural carbohydrates in biomass: Precision of a liquid chromatography method using a neutral detergent extraction and a charged aerosol detector.
Godin, B.; Agneessens, R.; Gerin, P. A.; Delcarte, J.
Talanta 85 (4), 2014–2026. 2011 Sep 30
Selectivity issues in targeted metabolomics: Separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography.
Hinterwirth, H.; Lämmerhofer, M.; Preinerstorfer, B.; Gargano, A.; Reischl, R.; Bicker, W.; Trapp, O.; Brecker, L.; Lindner, W.
J. Sep. Sci. 33 (21), 3273– 3282.
2010 Nov
Investigation of polar organic solvents compatible with Corona charged aerosol detection and their use for the determination of sugars by hydrophilic interaction liquid chromatography.
Hutchinson, J. P.; Remenyi, T.; Nesterenko, P.; Farrell, W.; Groeber, E.; Szucs, R.; Dicinoski, G.; Haddad, P. R.
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2012 Oct 31
Characterization of an endoglucanase belonging to a new subfamily of glycoside hydrolase family 45 of the basidiomycete Phanerochaete chrysosporium.
Igarashi, K.; Ishida, T.; Hori, C.; Samejima, M.
Appl. Environ. Microbiol. 74 (18), 5628–5634.
2008 Sep
Direct detection method of oligosaccharides by high- performance liquid chromatography with charged aerosol detection.
Inagaki, S.; Min, J. Z.; Toyo’oka, T. Biomed. Chromatogr. 21 (4), 338–342.
2007 Apr
Differential selectivity of the Escherichia coli cell membrane shifts the equilibrium for the enzyme-catalyzed isomerization of galactose to tagatose.
Kim, J. H.; Lim, B. C.; Yeom, S. J.; Kim, Y. S.; Kim, H. J.; Lee, J. K.; Lee, S. H.; Kim, S. W.; Oh, D. K.
Appl. Environ. Microbiol. 74 (8), 2307–2313.
2008 Apr
Elution strategies for reversed-phase high-performance liquid chromatography analysis of sucrose alkanoate regioisomers with charged aerosol detection.
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2013 Oct 11
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Design of experiments and multivariate analysis for evaluation of reversed-phase high-performance liquid chromatography with charged aerosol detection of sucrose caprate regioisomers.
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2013 Mar 15
Solvent effects on the retention of oligosaccharides in porous graphitic carbon liquid chromatography.
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2010 Sep 24
Practical preparation of lacto-N-biose I, a candidate for the bifidus factor in human milk.
Nishimoto, M.; Kitaoka, M. Biosci., Biotechnol., Biochem. 71 (8), 2101– 2104.
2007 Aug
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Appl. Environ. Microbiol. 76 (18), 6164–6170.
2010 Sep
1,2-alpha-l-Fucosynthase: A glycosynthase derived from an inverting alpha-glycosidase with an unusual reaction mechanism.
Wada, J.; Honda, Y.; Nagae, M.; Kato, R.; Wakatsuki, S.; Katayama, T.; Taniguchi, H.; Kumagai, H.; Kitaoka, M.; Yamamoto, K.
FEBS Lett. 582 (27), 3739– 3743.
2008 Nov 12
Efficient separation of oxidized cello-oligosaccharides generated by cellulose degrading lytic polysaccharide monooxygenases.
Westereng, B.; Agger, J. W.; Horn, S. J.; Vaaje-Kolstad, G.; Aachmann, F. L.; Stenstrøm, Y. H.; Eijsink, V. G.
J. Chromatogr., A. 1271 (1), 144–152.
2013 Jan 4
Distribution of in vitro fermentation ability of lacto-N-Biose I, a major building block of human milk oligosaccharides, in bifidobacterial strains.
Xiao, J. Z.; Takahashi, S.; Nishimoto, M.; Odamaki, T.; Yaeshima, T.; Iwatsuki, K.; Kitaoka, M.
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2010 Jan
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“Dilute-and-shoot” triple parallel mass spectrometry method for analysis of vitamin D and triacylglycerols in dietary supplements.
Byrdwell, W. C. Anal. Bioanal. Chem. 401 (10), 3317–3334.
2011 Dec
Photostability of rebaudioside A and stevioside in beverages. Clos, J. F.; Dubois, G. E.; Prakash, I.
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2008 Sep 24
Assessment of microcystin purity using charged aerosol detection.
Edwards, C.; Lawton, L. A. J. Chromatogr., A. 1217 (32), 5233–5238.
2010 Aug 6
Charged aerosol detection to characterize components of dispersed-phase formulations.
Fox, C. B.; Sivananthan, S. J.; Mikasa, T. J.; Lin, S.; Parker, S. C.
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2013 Nov
Determination of water-soluble vitamins in infant milk and dietary supplement using a liquid chromatography on-line coupled to a corona-charged aerosol detector.
Márquez-Sillero, I.; Cárdenas, S.; Valcárcel, M.
J. Chromatogr., A. 1313C, 253–258.
2013 Oct 25
Practical preparation of lacto-N-biose I, a candidate for the bifidus factor in human milk.
Nishimoto, M.; Kitaoka, M. Biosci., Biotechnol., Biochem. 71 (8), 2101- 2104.
2007 Aug
Nováková, L.; Solichová, D.; Solich, P.
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2009 May 22
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Comprehensive impurity profiling of nutritional infusion solutions by multidimensional off-line reversed-phase liquid chromatography × hydrophilic interaction chromatography-ion trap mass-spectrometry and charged aerosol detection with universal calibration.
Schiesel, S.; Lämmerhofer, M.; Lindner, W.
J. Chromatogr., A. 1259, 100–10.
2012 Oct 12
Direct separation and detection of biogenic amines by ion- pair liquid chromatography with chemiluminescent nitrogen detector.
Sun, J.; Guo, H. X.; Semin, D.; Cheetham, J.
J. Chromatogr., A. 1218 (29), 4689–4697.
2011 Jul 22
Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry.
Zhu, L.; Hu, Z.; Gamez, G.; Law, W. S.; Chen, H.; Yang, S.; Chingin, K.; Balabin, R. M.; Wang, R.; Zhang, T.; Zenobi, R.
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2010 Sep
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From lipid analysis towards lipidomics, a new challenge for the analytical chemistry of the 21st century. Part I: Modern lipid analysis.
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2009 Mar
Improving the universal response of evaporative light scattering detection by mobile phase compensation.
de Villiers, A.; Górecki, T.; Lynen, F.; Szucs, R.; Sandra, P.
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2007 Aug 17
Development and testing of a detection method for liquid chromatography based on aerosol charging.
Dixon, R. W.; Peterson, D. S. Anal. Chem. 74 (13), 2930– 2937.
2002 Jul 1
Charged aerosol detection to characterize components of dispersed-phase formulations.
Fox, C. B.; Sivananthan, S. J.; Mikasa, T. J.; Lin, S.; Parker, S. C.
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2013 Nov
HPLC analysis of nonvolatile analytes using charged aerosol detection.
Gamache, P.; McCarthy, R.; Freeto, S. M.; Asa, D.; Woodcock, M.; Laws, K.; Cole, R.
LC-GC North America 23, 150–161.
2005 Feb 1
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2006 May 1
2007 Nov 2
Comparison of the response of four aerosol detectors used with ultra high pressure liquid chromatography.
Hutchinson, J. P.; Li, J.; Farrell, W.; Groeber, E.; Szucs, R.; Dicinoski, G.; Haddad, P. R.
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2011 Mar 25
Universal response model for a corona charged aerosol detector.
Hutchinson, J. P.; Li, J.; Farrell, W.; Groeber, E.; Szucs, R.; Dicinoski, G.; Haddad, P. R.
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2010 Nov 19
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Effects of eluent temperature and elution bandwidth on detection response for aerosol-based detectors.
Khandagale, M. M.; Hutchinson, J. P.; Dicinoski, G. W.; Haddad, P. R.
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2013 Sep 20
Development and evaluation of Corona charged aerosol detection (CAD): A new universal detector for HPLC.
McCarthy, R.; Gamache, P.; Asa, D.
LabPlus international. 2005 Jun
Comparison of the sensitivity of evaporative universal detectors and LC/MS in the HILIC and the reversed-phase HPLC modes.
Mitchell, C. R.; Bao, Y.; Benz, N. J.; Zhang, S.
J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 877 (32), 4133–4139.
2009 Dec 15
The successful implementation of Corona CAD technology in HPLC laboratories across a wide range of industries.
Ramsey, N. Chromatography 27 (Suppl. 2), 77–78.
2006
A new universal detector, Corona charged aerosol detection. Senda, M.; Fukushima, K.; Hashiguchi, K.; Matsumoto, T.; Gamache, P.; Waraska, J.; Asa, D.
Chromatography 27 (3), 119–124.
2006
A new universal detector, Corona charged aerosol detector and its applications.
Senda, M.; Kanedai, Y.; Fukushima, K.; Hirose, K.; Hashiguchi, K.; Matsumoto, T.
Chromatography 27 (Suppl. 1), 39–42.
2006
Evaluation of column bleed by using an ultraviolet and a charged aerosol detector coupled to a high-temperature liquid chromatographic system.
Teutenberg, T.; Tuerk, J.; Holzhauser, M.; Kiffmeyer, T. K.
J. Chromatogr., A. 1119 (1–2), 197–201.
2006 Jun 30
Review of operating principle and applications of the charged aerosol detector.
Vehovec, T.; Obreza, A. J. Chromatogr., A. 1217 (10), 1549–1556.
2010 Mar 5
Vervoort, N.; Daemen, D.; Török, G.
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2008 May 2
Determination of relative response factors for chromatographic investigations using NMR spectrometry.
Webster, G. K.; Marsden, I.; Pommerening, C. A.; Tyrakowski, C. M.; Tobias, B.
J. Pharm. Biomed. Anal. 49 (5), 1261–1265.
2009 Jul 12
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Development of analytical procedures to study changes in the composition of meat phospholipids caused by induced oxidation.
Cascone, A.; Eerola, S.; Ritieni, A.; Rizzo, A.
J. Chromatogr., A 1120 (1–2), 211–220.
2006 Jul 7
Evaporative light scattering and charged aerosol detector. Chaminade, P. Chapter 5. In Hyphenated and Alternative Methods of Detection in Chromatography, Chromatographic Science Series; Shalliker, A., Ed.; Taylor & Francis Group, LLC: Boca Raton, FL.; 145–160.
2012
Simple and efficient profiling of phospholipids in phospholipase D-modified soy lecithin by HPLC with charged aerosol detection.
Damnjanovic, J.; Nakano, H.; Iwasaki, Y.
J. Am. Oil Chem. Soc. 90 (7), 951–957.
2013 Jul
Discriminating olive and non-olive oils using HPLC-CAD and chemometrics.
de la Mata-Espinosa, P.; Bosque- Sendra, J. M.; Bro, R.; Cuadros- Rodríguez, L.
Anal. Bioanal. Chem. 399 (6), 2083–2092.
2011 Feb
Olive oil quantification of edible vegetable oil blends using triacylglycerols chromatographic fingerprints and chemometric tools.
de la Mata-Espinosa, P.; Bosque- Sendra, J. M.; Bro, R.; Cuadros- Rodríguez, L.
Talanta 85 (1), 177–182. 2011 Jul 15
Quantification of triacylglycerols in olive oils using HPLC-CAD. de la Mata-Espinosa, P.; Bosque- Sendra, J.; Cuadros-Rodriguez, L.
Food Analytical Methods 4 (4), 574–581.
2011 Dec
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Quantification of pegylated phospholipids decorating polymeric microcapsules of perfluorooctyl bromide by reverse phase HPLC with a charged aerosol detector.
Díaz-López, R.; Libong, D.; Tsapis, N.; Fattal, E.; Chaminade, P.
J. Pharm. Biomed. Anal. 48 (3), 702–707.
2008 Nov 4
Squalene emulsions for parenteral vaccine and drug delivery. Fox, C. B. Molecules 14 (9), 3286– 3312.
2009 Sep 1
Interactions between parenteral lipid emulsions and container surfaces.
Gonyon, T.; Tomaso, A.; Kotha, P.; Owen, H.; Patel, D.; Carter, P.; Cronin, J.; Green, J.
PDA J. Pharm. Sci. and Tech. 67 (3), 247–254.
2013 May–Jun
Iwasaki, Y.; Masayama, A.; Mori, A.; Ikeda, C.; Nakano, H.
J. Chromatogr., A 1216 (32), 6077–6080.
2009 Aug 7
Determination of phospholipid and its degradation products in liposomes for injection by HPLC-charged aerosol detection (CAD).
Jiang, Q.; Yang, R.; Mei, X. Chinese Pharmaceutical Journal (Zhongguo Yaoxue Zazhi, Beijing, China) 42 (23), 1794–1796.
2007
Rapid quantification of yeast lipid using microwave-assisted total lipid extraction and HPLC-CAD.
Khoomrung, S.; Chumnanpuen, P.; Jansa-Ard, S.; Ståhlman, M.; Nookaew, I.; Borén, J.; Nielsen, J.
Anal. Chem. 85 (10), 4912– 4919.
2013 May 21
A new liquid chromatography method with charge aerosol detector (CAD) for the determination of phospholipid classes. Application to milk phospholipids.
Kieibowicz, G.; Micek, P.; Wawrzenczyk, C.
Talanta 105, 28–33. 2013 Feb 15
Title Authors Publication Publication Date
An LC method for the analysis of phosphatidylcholine hydrolysis products and its application to the monitoring of the acyl migration process.
Kiebowicz, G.; Smuga, D.; Gadkowski, W.; Chojnacka, A.; Wawrzenczyk, C.
Talanta 94, 22–29. 2012 May 30
Separation of acylglycerols, FAME and FFA in biodiesel by size exclusion chromatography.
Kittirattanapiboon, K.; Krisnangkurá, K.
2008 Mar 17
Quantitation of triacylglycerols from plant oils using charged aerosol detection with gradient compensation.
Lísa, M.; Lynen, F.; Holcapek, M.; Sandra, P.
J. Chromatogr., A. 1176 (1–2), 135–142.
2007 Dec 28
Quantitative study of the stratum corneum lipid classes by normal phase liquid chromatography: comparison between two universal detectors.
Merle, C.; Laugel, C.; Chaminade, P.; Baillet-Guffroy, A.
J. Liq. Chromatogr. Relat. Technol. 33, 629–644.
2010 Mar
The analysis of lipids via HPLC with a charged aerosol detector.
Moreau, R. A. Lipids 41 (7), 727–34. 2006 Jul
Lipid analysis via HPLC with a charged aerosol detector. Moreau, R. A. Lipid Technol. 21 (8–9), 191–194.
2009 Oct 23
Extraction and analysis of food lipids. Moreau, R. A.; Winkler-Moser, J. K.
Chapter 6. In Methods of Analysis of Food Components and Additives, Second Edition; Ötles, S., Ed.; Taylor & Francis Group, LLC: Boca Raton, FL.; 115–134.
2011 Nov
Aerosol based detectors for the investigation of phospholipid hydrolysis in a pharmaceutical suspension formulation.
Nair, L.; Werling, J. J. Pharm. Biomed. Anal. 49 (1), 95–99.
2009 Jan 15
Pharmaceutical Polymers/ Surfactants
Structure/function relationships of adipose phospholipase A2 containing a cys-his-his catalytic triad.
Pang, X. Y.; Cao, J.; Addington, L.; Lovell, S.; Battaile, K. P.; Zhang, Rao, J. L.; Dennis, E. A.; Moise, A. R.
J. Biol. Chem. 287 (42), 35260–35274.
2012 Oct 12
Simultaneous assessment of lipid classes and bile acids in human intestinal fluid by solid-phase extraction and HPLC methods.
Persson, E.; Löfgren, L.; Hansson, G.; Abrahamsson, B.; Lennernäs, H.; Nilsson, R.
J. Lipid Res. 48 (1), 242– 251.
2007 Jan
The use of charged aerosol detection with HPLC for the measurement of lipids.
Plante, M.; Bailey, B.; Acworth, I. Methods Mol. Biol. (Totowa, NJ, U.S.) 579, 469–482.
2009
Comparison between charged aerosol detection and light scattering detection for the analysis of Leishmania membrane phospholipids.
Ramos, R. G.; Libong, D.; Rakotomanga, M.; Gaudin, K.; Loiseau, P. M.; Chaminade, P.
J. Chromatogr., A. 1209 (1–2), 88–94.
2008 Oct 31
Ruiz-Samblás, C.; Arrebola- Pascual, C.; Tres, A.; van Ruth, S.; Cuadros-Rodríguez, L.
Talanta. 116, 788–793. 2013 Nov 15
Simple and precise detection of lipid compounds present within liposomal formulations using a charged aerosol detector.
Schönherr, C.; Touchene, S.; Wilser, G.; Peschka-Süss, R.; Francese, G.
J. Chromatogr., A. 1216 (5), 781–786.
2009 Jan 30
Determination of intralumenal individual bile acids by HPLC with charged aerosol detection.
Vertzoni, M.; Archontaki, H.; Reppas, C.
J. Lipid Res. 49 (12), 2690–2695.
2008 Dec
Neurolipids and the use of a charged aerosol detector. Waraska, J.; Acworth, I. Am. Biotechnol. Lab. 26 (1), 12–13.
2008
Pharmaceutical Polymers/ Surfactants
Improving the universal response of evaporative light scattering detection by mobile phase compensation.
de Villiers, A.; Górecki, T.; Lynen, F.; Szucs, R.; Sandra, P.
J. Chromatogr., A 1161 (1–2), 183–191.
2007 Aug 17
Díaz-López, R.; Libong, D.; Tsapis, N.; Fattal, E.; Chaminade, P.
J. Pharm. Biomed. Anal. 48 (3), 702–707.
2008 Nov 4
Phospholipid decoration of microcapsules containing perfluorooctyl bromide used as ultrasound contrast agents.
Díaz-López, R.; Tsapis, N.; Libong, D.; Chaminade, P.; Connan, C.; Chehimi, M. M.; Berti, R.; Taulier, N.; Urbach, W.; Nicolas, V.; Fattal, E.
Biomaterials 30 (8), 1462– 1472.
2009 Mar
Aerosol-based detectors for liquid chromatography: Do they have a role in bioanalysis?
Dixon, R. W. Bioanalysis 1 (8), 1389– 1392.
2009 Nov
Górecki, T.; Lynen, F.; Szucs, R.; Sandra, P.
Anal. Chem. 78 (9), 3186– 3192.
2006 May 1
2007 Nov 2
Characterization of an endoglucanase belonging to a new subfamily of glycoside hydrolase family 45 of the basidiomycete Phanerochaete chrysosporium.
Igarashi, K.; Ishida, T.; Hori, C.; Samejima, M.
Appl. Environ. Microbiol. 74 (18), 5628–5634.
2008 Sep
Serial coupling of reversed-phase and hydrophilic interaction liquid chromatography to broaden the elution window for the analysis of pharmaceutical compounds.
Louw, S.; Pereira, A. S.; Lynen, F.; Hanna-Brown, M.; Sandra, P.
J. Chromatogr., A 1208 (1- 2), 90–94.
2008 Oct 24
Determination of parabens in cosmetic products using multi- walled carbon nanotubes as solid phase extraction sorbent and corona-charged aerosol detection system.
Márquez-Sillero, I.; Aguilera- Herrador, E.; Cárdenas, S.; Valcárcel, M.
J. Chromatogr., A. 1217 (1), 1–6.
2010 Jan 1
Pharmaceutical Polymers/ Surfactants
Bioactive contaminants leach from disposable laboratory plasticware.
McDonald, G. R.; Hudson, A. L.; Dunn, S. M. J.; You, H.; Baker, G. B.; Whittal, R. M.; Martin, J. W.; Jha, A.; Edmondson, D. E.; Holt, A.
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Enzymatic reaction coupled with flow-injection analysis with charged aerosol, coulometric, or amperometric detection for estimation of contamination of the environment by pesticides.
Mikelova, R.; Prokop, Z.; Stejskal, K.; Adam, V.; Beklova, M.; Trnkova, L.; et al.
Chromatographia 67 (Suppl. 1), 47–53.
2008 May
Enzymatic reaction coupled with flow-injection analysis with charged aerosol, coulometric, or amperometric detection for estimation of contamination of the environment by pesticides.
Mikelova, R.; Prokop, Z.; Stejskal, K.; Adam, V.; Beklova, M.; Trnkova, L.; Kulichova, B.; Horna, A.; Chaloupkova, R.; Damborsky, J.; Kizek, R.
Chromatographia 67 (1), 47–53.
2008 May 1
Implementation of charged aerosol detection in routine reversed phase liquid chromatography methods.
Reilly, J.; Everatt, B.; Aldcroft, C. J. Liq. Chromatogr. Relat. Technol. 31, 3132–3142.
2008
The corona charged aerosol detector for liquid chromatography and high field asymmetric waveform ion mobility spectrometry combined with liquid chromatography/ mass spectrometry and gas chromatography.
Sherma, J.; Larkin, J. D.; Larkin, F. H.
J. AOAC Int. 89 (1), 15A–19A.
2006 Jan–Feb
Pharmaceutical Polymers/ Surfactants
Validated HPLC method for the quantitative analysis of a 4-methanesulfonyl-piperidine hydrochloride salt.
Soman, A.; Jerfy, M.; Swanek, F. J. Liq. Chromatogr. Relat. Technol. 32 (7), 1000– 1009.
2009 Mar 9
Stojanovic, A.; Lämmerhofer, M.; Kogelnig, D.; Schiesel, S.; Sturm, M.; Galanski, M.; Krachler, R.; Keppler, B. K.; Lindner, W.
J. Chromatogr., A. 1209 (1–2), 179–187.
2008 Oct 31
Determination of relative response factors of impurities in paclitaxel with high performance liquid chromatography equipped with ultraviolet and charged aerosol detectors.
Sun, P.; Wang, X.; Alquier, L.; Maryanoff, C. A.
J. Chromatogr., A 1177 (1), 87–91.
2008 Jan 4
Quantitative comparison of a corona-charged aerosol detector and an evaporative light-scattering detector for the analysis of a synthetic polymer by supercritical fluid chromatography.
Takahashi, K.; Kinugasa, S.; Senda, M.; Kimizuka, K.; Fukushima, K.; Matsumoto, T.; Shibata, Y.; Christensen, J.
J. Chromatogr., A 1193 (1–2), 151–155.
2008 Jun 6
Evaluation of column bleed by using an ultraviolet and a charged aerosol detector coupled to a high-temperature liquid chromatographic system.
Teutenberg, T.; Tuerk, J.; Holzhauser, M.; Kiffmeyer, T. K.
J. Chromatogr., A 1119 (1–2), 197–201.
2006 Jun 30
1,2-α-L-Fucosynthase: A glycosynthase derived from an inverting a-glycosidase with an unusual reaction mechanism.
Wada, J.; Honda, Y.; Nagae, M.; Kato, R.; Wakatsuki, S.; Katayama, T.; Taniguchi, H.; Kumagai, H.; Kitaoka, M.; Yamamoto, K.
FEBS Lett. 582 (27), 3739– 3743.
2008 Nov 12
HPLC determinations of enantiomeric ratios. Wipf, P.; Werner, S.; Twining, L. A.; Kendall, C.
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Pharmaceutical Polymers/ Surfactants
Pharmaceutical Polymers/ Surfactants
Aqueous extract of Astragali Radix induces human natriuresis through enhancement of renal response to atrial natriuretic peptide.
Ai, P.; Yong, G.; Dingkun, G.; Qiuyu, Z.; Kaiyuan, Z.; Shanyan, L.
J. Ethnopharmacol. 116 (13), 413–421.
2008 Mar 28
Recent methodology in ginseng analysis. Baek, S.; Bae, O.; Park, J. J. Ginseng Res. 36 (2), 119–134.
2012 Apr
Sensitive determination of saponins in radix et rhizoma notoginseng by charged aerosol detector coupled with HPLC.
Bai, C.; Han, S.; Chai, X.; Jiang, Y.; Li, P.; Tu, P.
J. Liq. Chromatogr. Relat. Technol. 32 (2), 242–260.
2010 Aug 27
The real nature of the indole alkaloids in Cortinarius infractus: Evaluation of artifact formation through solvent extraction method development.
Brondz, I.; Ekeberg, D.; Høiland, K.; Bell, D.; Annino, A.
J. Chromatogr., A 1148 (1), 1–7.
2007 Apr 27
Brondz, I.; Høiland, K. Trends Chromatogr. 4, 79–87.
2008
Utilization of RP-HPLC fingerprinting analysis for the identification of diterpene glycosides from Stevia rebaudiana.
Chaturvedula, V.; Prakash, I. Int. J. Res. Phytochem. Pharmacol. 1 (2), 88–92.
2011 Jun 9
Acid and alkaline hydrolysis studies of stevioside and rebaudioside A.
Chaturvedula, V.; Prakash, I. J. Appl. Pharm. Sci. 1 (8), 104–108.
2011 Oct
Spectral analysis and chemical studies of the sweet constituent, rebaudioside A.
Chaturvedula, V.; Prakash, I. Eur. J. Med. Plants 2 (1), 57–65.
2012 Feb
Photostability of rebaudioside A and stevioside in beverages. Clos, J. F.; DuBois, G. E.; Prakash, I.
J. Agric. Food Chem. 56 (18), 8507–8513.
2008 Sep 24
Comparison between evaporative light scattering detection and charged aerosol detection for the analysis of saikosaponins.
Eom, H. Y.; Park, S. Y.; Kim, M. K.; Suh, J. H.; Yeom, H.; Min, J. W.; Kim, U.; Lee, J.; Youm, J. R.; Han, S. B.
J. Chromatogr., A. 1217 (26), 4347–4354.
2010 Jun 25
HPLC with charged aerosol detection for the measurement of natural products.
Fukushima, K.; Kanedai, Y.; Hirose, K.; Matsumoto, T.; Hashiguchi, K.; Senda, M.; et al.
Chromatography 27 (Suppl. 1), 83–86.
2006
Pharmaceutical Polymers/ Surfactants
Development and validation of HPLC-DAD-CAD-MS3 method for qualitative and quantitative standardization of polyphenols in Agrimoniae eupatoriae herba (Ph. Eur).
Granica, S.; Krupa, K.; Kebowska, A.; Kiss, A. K.
J. Pharm. Biomed. Anal. 86, 112–122.
2013 Dec
A new application of charged aerosol detection in liquid chromatography for the simultaneous determination of polar and less polar ginsenosides in ginseng products.
Jia, S.; Li, J.; Yunusova, N.; Park, J. H.; Kwon, S. W.; Lee, J.
Phytochem. Anal. 24 (4), 374–380.
2013 Jul–Aug
Analysis of terpene lactones in a Ginkgo leaf extract by high- performance liquid chromatography using charged aerosol detection.
Kakigi, Y.; Mochizuki, N.; Icho, T.; Hakamatsuka, T.; Goda, Y.
Biosci., Biotechnol., Biochem. 74 (3), 590–594.
2010
Linear aglycones are the substrates for glycosyltransferase DesVII in methymycin biosynthesis: analysis and implications.
Kao, C.; Borisova, S.; Kim, H.; Liu, H.
J. Am. Chem. Soc. 128 (17), 5606–5607.
2006 May 3
Certification of a pure reference material for the ginsenoside Rg1.
Kim, D.; Chang, J.; Sohn, H.; Cho, B.; Ko, S.; Nho, K.; Jang, D.; Lee, S.
Accredit. Qual. Assur. 15 (2), 81–87.
2009 Sep
Optimization of pressurized liquid extraction for spicatoside A in Liriope platyphylla.
Kim, S. H.; Kim, H. K.; Yang, E. S.; Lee, K. Y.; Kim, S. D.; Kim, Y. C.; Sung, S. H.
Sep. Purif. Technol. 71 (2), 168–172.
2010
Production of surfactin and iturin by Bacillus licheniformis N1 responsible for plant disease control activity.
Kong, H. G.; Kim, J. C.; Choi, G. J.; Lee, K. Y.; Kim, H. J.; Hwang, E. C.; Moon, B. J.; Lee, S. W.
Plant Pathol. J. 26 (2), 170–177.
2010
Photodiode array (PDA) and other detection methods in HPLC of plant metabolites.
Markowski, W.; Waksmundzka- Hajnos, M.
Chapter 13. In High Performance Liquid Chromatography in Phytochemical Analysis, Chromatographic Science Series, Markowski, W., Sherma, J., Eds.; Taylor & Francis Group, LLC: Boca Raton, FL; 331–350.
2010 Nov
Natural Products/Supplements
High-performance liquid chromatography analysis of plant saponins: An update 2005-2010.
Negi, J. S.; Singh, P.; Pant, G. J.; Rawat, M. S.
Pharmacogn. Rev. 5 (10), 155–158.
2011 Jul
Poplawska, M.; Blazewicz, A.; Bukowinska, K.; Fijalek, Z.
J. Pharm. Biomed. Anal. 84, 232–243.
2013 Oct
Isolation and analysis of ginseng: advances and challenges. Qi, L.; Wang, C.; Yuan, C. Nat. Prod. Rep. 28 (3), 467–495.
2011 Mar
Sasaki, E.; Ogasawara, Y.; Liu, H. W.
J. Am. Chem. Soc. 132 (21), 7405–7417.
2010 Jun 2
Rapid purification method for fumonisin B1 using centrifugal partition chromatography.
Szekeres, A.; Lorántfy, L.; Bencsik, O.; Kecskeméti, A.; Szécsi, Á.; Mesterházy, Á.; Vágvölgyi, C.
Food Addit. Contam. 30 (1), 147–155.
2013
Performance evaluation of charged aerosol and evaporative light scattering detection for the determination of ginsenosides by LC.
Wang, L.; He, W. S.; Yan, H. X.; Jiang, Y.; Bi, K. S.; Tu, P. F.
Chromatographia 70 (3–4), 603–608.
2009 Aug
HPLC in natural product analysis: The detection issue. Wolfender, J. L. Planta Med. 75 (07), 719– 734.
2009 Jun
Simultaneous determination of triterpenoid saponins from pulsatilla koreana using high performance liquid chromatography coupled with a charged aerosol detector (HPLC-CAD).
Yeom, H.; Suh, J. H.; Youm, J. R.; Han, S. B.
Bull. Korean Chem. Soc. 31 (5), 1159–1164.
2010
Pharmaceutical Polymers/ Surfactants
Pharmaceutical Polymers/ Surfactants
Charged aerosol detection in pharmaceutical analysis. Almeling, S.; Ilko, D.; Holzgrabe, U.
J. Pharm. Biomed. Anal. 69, 50–63.
2012 Oct
Quantitation of acetol in common pharmaceutical excipients using LC–MS.
Beilin, E.; Baker, L. J.; Culbert, P.; Toltl, N. P.
J. Pharm. Biomed. Anal. 46 (2), 316–321.
2008 Jan 22
Determination of pancuronium and its impurities in pharmaceutical preparation by LC with charged aerosol detection.
Bazewicz, A.; Fijaek, Z.; Sarna, K.; Warowna-Grzeskiewicz, M.
Chromatographia 72 (1–2), 183–186.
2010 Jul
Bazewicz, A.; Fijaek, Z.; Warowna-Grzeskiewicz, M.; Jadach, M.
J. Chromatogr., A. 1217 (8), 1266–1272.
2010 Feb 19
Anal. Chem. 79 (6), 2472– 2482.
2007 Mar 15
Hydrophilic interaction chromatography with aerosol-based detectors (ELSD, CAD, NQAD) for polar compounds lacking a UV chromophore in an intravenous formulation.
Cintrón, J. M.; Risley, D. S. J. Pharm. Biomed. Anal. 78–79, 14–18.
2013 May 5
Crafts, C.; Bailey, B.; Gamache, P.; Liu, X.; Acworth, I.
Chapter 10. In Applications of Ion Chromatography in the Analysis of Pharmaceutical and Biological Products; Bhattacharyya, L., Rohrer, J. S., Eds.; Wiley: New Jersey, 221–236.
2012 Mar
Pharmaceutical Polymers/ Surfactants
Title Authors Publication Publication Date
Evaluation of methods for the simultaneous analysis of cations and anions using HPLC with charged aerosol detection and a zwitterionic stationary phase.
Crafts, C.; Bailey, B.; Plante, M.; Acworth, I.
J. Chromatogr. Sci. 47 (7), 534–539.
2009 Aug
HILIC methods in pharmaceutical analysis. Dejaegher, B.; Heyden, Y. J. Sep. Sci. 33 (6–7), 698– 715.
2010 Mar
Díaz-López, R.; Libong, D.; Tsapis, N.; Fattal, E.; Chaminade, P.
J. Pharm. Biomed. Anal. 48 (3), 702–707.
2008 Nov 4
Fireman, J.; Carter, D.; Wallace, M.
Am. Biotechnol. Lab. 25, 18.
2007
Forsatz, B.; Snow, N. LC-GC North America 25 (9), 960.
2007 Sep 1
Squalene emulsions for parenteral vaccine and drug delivery. Fox, C. B. Molecules 14 (9), 3286– 3312.
2009 Sep 1
Monitoring the effects of component structure and source on formulation stability and adjuvant activity of oil-in-water emulsions.
Fox, C. B.; Anderson, R. C.; Dutill, T. S.; Goto, Y.; Reed, S. G.; Vedvick, T. S.
Colloids Surf., B 65 (1), 98–105.
2008 Aug 1
Effects on immunogenicity by formulations of emulsion-based adjuvants for malaria vaccines.
Fox, C. B.; Baldwin, S. L.; Vedvick, T. S.; Angov, E.; Reed, S. G.
Clin. Vaccine Immunol. 19 (10), 1633–1640.
2012 Oct
Gaberc-Porekar, V.; Zore, I.; Podobnik, B.; Menart, V.
Curr. Opin. Drug Discovery Dev. 11 (2), 242–250.
2008 Mar
Gorecki, T.; Lynen, F.; Szucs, R.; Sandra, P.
Anal. Chem. 78 (9), 3186– 3192.
2006 May 1
Pharmaceutical Polymers/ Surfactants
Title Authors Publication Publication Date
Control of impurities in L-aspartic acid and L-alanine by high- performance liquid chromatography coupled with a corona charged aerosol detector.
Holzgrabe, U.; Nap, C. J.; Almeling, S.
J. Chromatogr., A. 1217 (3), 294–301.
2010 Jan 15
Alternatives to amino acid analysis for the purity control of pharmaceutical grade L-alanine.
Holzgrabe, U.; Nap, C. J.; Beyer, T.; Almeling, S.
J. Sep. Sci. 33 (16), 2402– 2410.
2010 Aug
Development of a reversed-phase HPLC impurity method for a UV variable isomeric mixture of a CRF drug substance intermediate with the assistance of Corona CAD.
Huang, Z.; Neverovitch, M.; Lozano, R.; Tattersall, P.; Ruan, J.
J. Pharm. Innov. 6 (2), 115–123.
2011 Jun
Determination of inorganic pharmaceutical counterions using hydrophilic interaction chromatography coupled with a Corona CAD detector.
Huang, Z.; Richards, M. A.; Zha, Y.; Francis, R.; Lozano, R.; Ruan, J.
J. Pharm. Biomed. Anal. 50 (5), 809–814.
2009 Dec 5
Forced degradation and impurity profiling: Recent trends in analytical perspectives.
Jain, D.; Basniwal, P. K. J. Pharm. Biomed. Anal. 86, 11–35.
2013 Jul 31
Non-derivatization method for the determination of gabapentin in pharmaceutical formulations, rat serum and rat urine using high performance liquid chromatography coupled with charged aerosol detection.
Jia, S.; Lee, H.S.; Choi, M.J.; Sung, S.H.; Han, S.B.; Park, J.H.; Hong, S.S.; Kwon, S.W.; Lee, J.
Curr. Anal. Chem. 8 (1), 159–167.
2012
Comparison of two aerosol-based detectors for the analysis of gabapentin in pharmaceutical formulations by hydrophilic interaction chromatography.
Jia, S.; Park, J. H.; Lee, J.; Kwon, S. W.
Talanta 85 (5), 2301–2306. 2011 Oct 15
Linear aglycones are the substrates for glycosyltransferase DesVII in methymycin biosynthesis: analysis and implications.
Kao, C. L.; Borisova, S. A.; Kim, H. J.; Liu, H. W.
J. Am. Chem. Soc. 128 (17), 5606–5607.
2006 May 3
Ion chromatography coupled to universal detectors for the analysis of pharmaceutically-related anions.
Karu, N.; Hutchinson, J. P.; Dicinoski, G. W.; Hanna-Brown, M.; Haddad, P. R.
Sep. Sci. 4 (14), 14–19. 2012
Pharmaceutical Polymers/ Surfactants
Determination of pharmaceutically related compounds by suppressed ion chromatography: IV. Interfacing ion chromatography with universal detectors.
Karu, N.; Hutchinson, J. P.; Dicinoski, G. W.; Hanna-Brown, M.; Srinivasan, K.; Pohl, C. A.; Haddad, P. R.
J. Chromatogr., A. 1253, 44–51.
2012 Aug 31
PEGylation of cholecystokinin prolongs its anorectic effect in rats.
León-Tamariz, F.; Verbaeys, I.; Van Boven, M.; De Cuyper, M.; Buyse, J.; Clynen, E.; Cokelaere, M.
Peptides 28 (5), 1003– 1011.
2007 May
Liu, X. K.; Fang, J. B.; Cauchon, N.; Zhou, P.
J. Pharm. Biomed. Anal. 46 (4), 639–644.
2008 Mar 13
Evaluation of charged aerosol detection (CAD) as a complementary technique for high-throughput LC-MS-UV- ELSD analysis of drug discovery screening libraries.
Loughlin, J.; Phan, H.; Wan, M.; Guo, S.; May, K.; Lin, B.
American Laboratory 39, 24.
Serial coupling of reversed-phase and hydrophilic interaction liquid chromatography to broaden the elution window for the analysis of pharmaceutical compounds.
Louw, S.; Pereira, A.; Lynen, F.; Hanna-Brown, M.; Sandra, P.
J. Chromatogr., A. 1208 (1–2), 90–94.
2008 Oct 24
McCarthy, R.; Gamache, P.; Asa, D.
G.I.T. Laboratory Journal Europe 9, (4), 26–27.
2005
Aerosol based detectors for the investigation of phospholipid hydrolysis in a pharmaceutical suspension formulation.
Nair, L. M.; Werling, J. O. J. Pharm. Biomed. Anal. 49 (1), 95–99.
2009 Jan 15
Comparison of UV and charged aerosol detection approach in pharmaceutical analysis of statins.
Nováková, L.; Lopéz, S. A.; Solichová, D.; Satínský, D.; Kulichová, B.; Horna, A.; Solich, P.
Talanta 78 (3), 834–839. 2009 May 15
Novel MS solutions inspired by MIST. Ramanathan, R.; Josephs, J. L.; Jemal, M.; Arnold, M.; Humphreys, W. G.
Bioanalysis 2 (7), 1291– 1313.
2010 Jul
Pharmaceutical Polymers/ Surfactants
Title Authors Publication Publication Date
The effect of composting on the degradation of a veterinary pharmaceutical.
Ramaswamy, J.; Prasher, S. O.; Patel, R. M.; Hussain, S. A.; Barrington, S. F.
Bioresour Technol. 101 (7), 2294–2299.
2010 Apr
Implementation of charged aerosol detection in routine reversed phase liquid chromatography methods.
Reilly, J.; Everatt, B.; Aldcroft, C. J. Liq. Chromatogr. Relat. Technol. 31 (20), 3132– 3142.
2008 Oct 22
Rystov, L.; Chadwick, R.; Krock, K.; Wang, T.
J. Pharm. Biomed. Anal. 56 (5), 887–894.
2011 Dec 15
Comparison of ultraviolet detection, evaporative light scattering detection and charged aerosol detection methods for liquid-chromatographic determination of anti-diabetic drugs.
Shaodong, J.; Lee, W. J.; Ee, J. W.; Park, J. H.; Kwon, S. W.; Lee, J.
J. Pharm. Biomed. Anal. 51 (4), 973–978.
2010 Mar 11
Applications of the charged aerosol detector in compound management.
Sinclair, I.; Charles, I. J. Biomol. Screening 14 (5), 531–537.
2009 Jun
Charged aerosol detection: Factors for consideration in its use as a generic quantitative detector.
Sinclair, I.; Gallagher, R. Chromatography Today 1 (3), 5–9.
2008 Jun
Determination of relative response factors of impurities in paclitaxel with high performance liquid chromatography equipped with ultraviolet and charged aerosol detectors.
Sun, P.; Wang, X.; Alquier, L.; Maryanoff, C.
J. Chromatogr., A. 1177 (1), 87–91.
2008 Jan 4
Vervoort, N.; Daemen, D.; Török, G.
J. Chromatogr., A 1189 (1–2), 92–100.
2008 May 2
Neurolipids and the use of a charged aerosol detector. Waraska, J.; Acworth, I. N. American Biotech. Lab. 26 (1), 12–13.
2008
HPLC determinations of enantiomeric ratios. Wipf, P.; Werner, S.; Twining, L. A.; Kendall, C.
Chirality 19 (1), 5–9. 2007 Jan
Biosynthesis of fosfomycin, re-examination and re- confirmation of a unique Fe(II)- and NAD(P)H-dependent epoxidation reaction.
Yan, F.; Munos, J. W.; Liu, P.; Liu, H. W.
Biochemistry 45 (38), 11473–11481.
2006 Sep 26
A new approach to threshold evaluation and quantitation of unknown extractables and leachables using HPLC/CAD
Yu, X., Zdravkovic, S., Wood, D.; Li, C., Cheng, Y.; Ding, X.
Drug Delivery Technol. 9 (3), 50–55.
2009
Genotoxic impurities: A quantitative approach. Yuabova, Z. Y.; Holschlag, D. R.; Rodriguez, S. A.; Qin, C.; Papov, V. V.; Qiu, F.; McCaffrey, J. F.; Norwood, D. L.
J. Liq. Chromatogr. Relat. Technol. 31, 2318–2330.
2008 Aug 7
Advances in HPLC detection—towards universal detection. Zhang, B.; Li, X.; Yan, B. Anal. Bioanal. Chem. 390 (1), 299–301.
2008 Jan
Analysis of pharmaceutical impurities using multi-heart cutting 2D LC coupled with UV-charged aerosol MS detection.
Zhang, K.; Li, Y.; Tsang, M.; Chetwyn, N. P.
J. Sep. Sci. 36 (18), 2986– 2992.
2013 Sep
Pharmaceutical Polymers/ Surfactants
Pharmaceutical Polymers/ Surfactants
Quantitation of acetol in common pharmaceutical excipients using LC–MS.
Beilin, E.; Baker, L. J.; Culbert, P.; Toltl, N. P.
J. Pharm. Biomed. Anal. 46 (2), 316–321.
2008 Jan 22
Christiansen, A.; Backensfeld, T.; Kühn, S.; Weitschies, W.
J. Pharm. Sci. 100 (5), 1773–1782.
2011 May
Stability of the non-ionic surfactant polysorbate 80 investigated by HPLC-MS and charged aerosol detector.
Christiansen, A.; Backensfeld, T.; Kühn, S.; Weitschies, W.
Pharmazie 66 (9), 666–671. 2011 Sep
Investigating the stability of the nonionic surfactants tocopheryl polyethylene glycol succinate and sucrose laurate by HPLC–MS, DAD, and CAD.
Christiansen, A.; Backensfeld, T.; Kühn, S.; Weitschies, W.
J. Pharm. Sci. 100 (5), 1773–1782.
2011 May
Fast and sensitive determination of Polysorbate 80 in solutions containing proteins.
Fekete, S.; Ganzler, K.; Fekete, J. J. Pharm. Biomed. Anal. 52 (5), 672–9.
2010 Sep 5
HPLC with charged aerosol detection for the measurement of different non-ionic surfactants.
Fukushima, K.; Matsumoto, T.; Hashiguchi, K.; Senda, M.; Carreiro, D.; Asa, D.; et al.
Chromatography 27 (Suppl. 2), 139–142.
2006
Greiderer, A.; Steeneken, L.; Aalbers, T.; Vivó-Truyols, G.; Schoenmakers, P.
J. Chromatogr., A. 1218 (34), 5787–5793.
2011 Aug 26
Size exclusion chromatography with Corona charged aerosol detector for the analysis of polyethylene glycol polymer.
Kou, D.; Manius, G.; Zhan, S.; Chokshi, H. P.
J. Chromatogr., A. 1216 (28), 5424–5428.
2009 Jul 10
Analysis of polysorbate 80 using fast HPLC and charged aerosol detection.
Lobback, C.; Backensfeild, T.; Funke, A.; Weltschies, W.
Pharm. Technol. 34 (5), 48. 2010 May
Quantitative determination of nonionic surfactants with CAD. Lobback, C.; Backensfeld, T.; Funke, A.; Weitschies, W.
Chromatography Techniques, 18.
Drug Discovery Dev. 10 (11, special section), 18.
2007 Nov
Analysis of quaternary ammonium and phosphonium ionic liquids by reversed-phase high performance liquid chromatography with charged aerosol detection and unified calibration.
Stojanovic, A.; Lämmerhofer, M.; Kogelnig, D.; Schiesel, S.; Sturm, M.; Galanski, M.; Krachler, R.; Keppler, B. K.; Lindner, W.
J. Chromatogr., A 1209 (1–2), 179–187.
2008 Oct 31
Quantitative comparison of a corona-charged aerosol detector and an evaporative light-scattering detector for the analysis of a synthetic polymer by supercritical fluid chromatography.
Takahashi, K.; Kinugasa, S.; Senda, M.; Kimizuka, K.; Fukushima, K.; Matsumoto, T.; Shibata, Y.; Christensen, J.
J. Chromatogr., A. 1193 (1–2), 151–155.
2008 Jun 6
SEC assay for polyvinylsulfonic impurities in 2-(N-morpholino) ethanesulfonic acid using a charged aerosol detector.
Zhang, T.; Hewitt, D.; Kao, Y. H. Chromatographia 72 (1–2), 145–149.
2010 Jul
Pharmaceutical Polymers/ Surfactants
Pharmaceutical Polymers/ Surfactants
Evaluation of charged aerosol detector for purity assessment of protein.
Wang, R.; Wang, X.; Paulino, J.; Alquier, L.
J. Chromatogr., A. 1283, 116–121.
2013 Mar 29
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