Chapter 5Chapter 5 NeoplasiaNeoplasia

Su Min (Su Min (苏敏）苏敏）

CPC-CASE ： (N0A6-1) A 37 year old man found a dark brown

lesion on the skin of his face, just in front of the ear. He ignored the lesion, even though it became larger and started to bleed. Then he began to develop many more spots on his face and neck. At this point, he went to the doctor who did a biopsy and gave him some treatment. However, he died 8 months later.

(Offered by Prof.Orr)

(Left) The early skin lesion. (Center) The appearance of the many lesions on his face and neck. (Right) The cut surface of his liver at autopsy.

(Left) A cross section of a rib at autopsy. (right) His heart at autopsy.

( Offered by Prof.Orr)

(Left) Histologic section of normal skin. (Right) Histologic section of a skin lesion.

(Offered by Prof.Orr)

What is your diagnosis?

What features of neoplastic disease are shown in these photographs?

Major Objectives:To master the concepts of:1. Atypia. 2. Tumor growth and spread, including dysplasia,

carcinoma in situ, invasion and metastasis.3. Differences between benign and malignant

tumors, carcinoma and sarcoma.4. Nomenclature and principles of classification.5. Pathological and clinical features of common

tumors.To understand the etiological factors and cellular

mechanisms involved in tumor development.

The Variety of Tumors on Appearance

右颈部囊状水瘤(Prof.Orr 提供 )

血管瘤(Prof.Orr 提供 )

(Prof.Orr 提供 )

引自 Cancers.net

引自 Cancers.net

引自 Cancers.net

引自 Cancers.net

引自 Cancers.net

引自 Cancers.net

引自 Cancers.net

引自 Cancers.net

Neoplasia is a common Neoplasia is a common disease, especially malignant disease, especially malignant tumors which damaged human tumors which damaged human health severelyhealth severely

The death of malignant tumors

About 7,000,000 in the would

About 1,000,000 in China

The death of cancer accounting for all deaths:

the first cause in Chinese city the second cause in Chinese

countryside

The ten commonest malignant tumors in Chinese: Respiratory tract:

lung cancer nasopharyngeal

carcinoma

The ten commonest malignant tumors in Chinese:

Gastrointestinal tract:

. esophageal cancer stomach cancer large intestine cancer liver

cancer,

The ten commonest malignant tumors in Chinese:

Female genital:

breast cancer ovary cancer

Offered by Prof.Song W.Wong

The ten commonest malignant tumors in Chinese:

lymphomas leukemia