CURRICULUMVITAEHSUEH-CHIACHANGGroup Website: www.nd.edu/~changlab Education B.S. CaliforniaInstituteofTechnology June1976 Ph.D. Princeton University June 1980

Professional Experience

2013-PresentFellow,NotreDameInstituteforAsiaandAsianStudies2011DistinguishedVisitingFellow,UKRoyalSocietyofEngineering,ImperialCollege.2010-2014 AdjunctProfessor,NationalTsingHuaUniversity2010-2014ChiefScientificAdvisor,FCubed,LLC2006-2018 FoundingandChiefEditor,Biomicrofluidics,AmericanInstituteofPhysics2005-2006 AdjunctProfessor,NationalChengKungUniversity2003-PresentDirector,CenterforMicrofluidicsandMedicalDiagnostics,UniversityofNotreDame1998-Present BayerProfessorofChemicalEngineering,NotreDame1993 SeniorVisitor,DepartmentofAppliedMathematicsandTheoreticalPhysics,UniversityofCambridge1989-1995 Chairman,Dept.ofChemicalEngineering,NotreDame1987-1998 Professor,UniversityofNotreDame1984-1987 AssociateProfessor,UniversityofHouston1983-1984 AssociateProfessor,UniversityofCalifornia,SantaBarbara1980-1983 AssistantProfessor,UniversityofCalifornia,SantaBarbara

Awards and Honors WallaceMemorialHonorAward,PrincetonUniversity,1978 Regent'sJuniorFacultyAward,UniversityofCalifornia,SantaBarbara,1980 PresidentialYoungInvestigatorAward,NationalScienceFoundation,1985 ColburnLecture,UniversityofDelaware,1988 SigmaXiOutstandingResearchAward,UniversityofNotreDame,1990 FrancoisN.FrenkielAward,FluidDynamicsDivisionofAmericanPhysicalSociety,1991 FellowoftheAmericanPhysicalSociety,elected1997 StanleyCorrsinHydrodynamicsLecture,JohnsHopkins2002

Founding and Chief Editor, Biomicrofluidics, American Institute of Physics, Appointed2006.

DistinguishedVisitingFellowAward,RoyalSocietyofEngineering,UK,2011. 1stSourceCommercializationAward,NotreDame,2013. DistinguishedLecture,MechanicalEngineering,BostonUniversity,2018.

Overview

ResearchAchievementsinChronologicalOrder:

1. 1977-89 Advanced understanding of ignition, oscillation and chaotic behavior inreactors.

2. 1987-90 Explained the effect of surfactants on bubble transport inmicrochannelsand analyzeddroplet transport/breakup innon-circular channels in anticipationofdropletmicrofluidics.

3. 1989-08 Developed a theory for wetting dynamics far from equilibrium andexplainedstick-slip ring-formationdynamicsduringdropevaporationandchemicalpatterning.

4. 1994-99Developedatheoryforrapidignitionofautomobilecatalyticconverters.5. 1994-04Delineatedwaveevolutiononafallingfilmandotherinterfacialpatternsby

developingaspectraltheoryforsolitarywaveinteraction.6. 2004-11 Invented several DC electro-osmotic pumps andAC dielectrophoretic cell

sortingandcharacterizationtechnologiesbasedonelectrokinetics.7. 2005-Present Discovered AC Nanocone, AC Electrospraying and Surface Acoustic

WaveNanodropGenerationandappliedtomassspectrometry,nanofiberspinning,exosomelysinganddropletdigitalPCR.

8. 2008-Present Verified themechanism for over-limiting ion current in ion-selectivemembranes and applied it to nucleic acid sensing in a biochip. Developed severalmolecular concentration/fractionation and pH generation on-chip membranetechnologies.

9. 2009-Present Invented a Carbon Nanotube dielectrophoretic assembly andalignmenttechnologyforbiosensingandFETcircuits.

10. 2015-PresentInventedasurface-modifiedsolid-statenanoporetechnologythatcandistinguish short ssDNA and dsDNA (or miRNA and their duplex) by theirtranslocationtimesthusavoidingPCRandligationbiasesduringquantification.

11. 2004-Present 28 IP disclosures represent highest in Notre Dame history. 10 havebeen patentedwith 5more pending. 3 have been licensed by startups,mid-sizecompaniesandconglomeratesforcommercialization.

AdministrativeExperienceDepartmentChairofChemicalandBiomolecularEngineering(1989-1995)HiredfivefacultymembersasChemicalEngineeringdepartmentChair(1989-95),includingthefirstwomantotheEngineeringCollege(Brennecke,memberofNAE).Mentoredfivejuniorfaculty:EdMaginn,ElaineZhu,DavidGo,ArezooArdekani,JeremyZartmanatNotreDame.FourwonNSFCareerAwardsandtwoarewomen.Researchexpendituredoubledduringchairmanship.

Founding Director of Center forMicrofluidics andMedical Diagnostics (CMMD, 2003-present).TheCenterinitiatedTechTransferatNotreDame.10issuedpatentsand5pending.Founding executive committee of the Notre Dame Advanced Diagnostics and TherapeuticsInitiative.Founding Editor of Biomicrofluidics, AIP’s first biological journal, and founded the AdvancedMicrofluidicsandNanofluidicsinternationalconferenceseries.AdvisoryCommitteetoVPofResearchNotreDame2016-18.TechTransferExperienceServedastheChiefScientificAdvisorofCubedLaboratorieshttp://cubedlabs.com/.Itwillbecomepublicin2018.TwomoretechnologieswerelicensedbyAgenDxin2014,astartupattheNotreDameInnovationPark.PreliminarylicensingagreementwithDolomite,amajormicrofluidiccompany.DevelopingaGMOfoodscreeningplatformwiththeFarEasternGroup.WontheNotreDame1stSourceCommercializationAward<http://www.insideindianabusiness.com/newsitem.asp?ID=59027>.EditorialExperienceFoundingandChiefEditorofBiomicrofluidicsoftheAmericanInstituteofPhysics(2006-2018).FirstAIPjournalinmedical/biologicalfields,firsttobeelectroniconlyandfirsttobeopen-access.FoundedanaffiliatedconferenceAdvancesinMicrofluidicsandNanofluidicsthathasbeenheldatHongKong,Singapore,Dalian,NotreDame,Taipei,Beijing,SingaporeandHobart.ItwillbereplacedbyanannualAIPHorizonsconferenceatNotreDame.PersonalStatementonRecentResearch/ProfessionalActivity(2004-2015)andVisionH-CChangisaleaderinelectrokinetics,animportantmicro/nanofluidictechnologyforbiochipplatforms in futurediseasediagnosticproducts. Hisapproachcombines insightful theoreticalanalysiswithsimplebutcreativeexperimentstouncovernewelectrokineticphenomenaortoverify speculated ones, among themAC cone spray/electrospinning, electrokineticmolecular

assay, nanocolloid dielectrophoresis, monolayer enabled field dissociation of water, field-inducedmicrovorticesnearion-selectivemedia,tipplasmonicsetc.Heisalsoabletoapplyandintegrate these new phenomena into several new microfluidic technologies for biosensing,massspectrometryandbioseparation.ChiaisthecoauthorofaseminalbookonElectrokineticsandheisthefoundingeditorofBiomicrofluidics,thefirstAmericanInstituteofPhysicsjournalinbiologyand the first tobeopen-access. In four years,hehas led the journal toan impactfactorof3.896in2010,whichranksitthetoporiginalresearchjournalinthefluidandplasmaphysics category. He is on the organization committee of several international microfluidicconferences, including AdvancedMicrofluidics and Nanofluidics, an annual Asian conferencethathefounded.ChiaistheDirectoroftheCenterforMicrofluidicsandMedicalDiagnosticsattheUniversityofNotreDame,wherehehas initiatedthefirst technologytransferefforts.HeandhisPhDandpostdocstudentsare inventorsof10NotreDamepatentsand5provisionalpatents,thelargestIPoutputfromanylabatNotreDame.Fivetechnologieshavebeenlicensedbystartups. OnestartupFCubedLLCis locatedatNotreDameandhasastaffof17.AnotherstartupAgenDxhas just licensedanotherofhistechnologies.Chiahasalsoworkedwith largecompanies like IBMand theFarEasternGroupon thenew technologies. Since2000,18PhDandpost-docstudentsoftheChanglaboratoryhaveembarkedonacademiccareersastenure-trackprofessorsatChemicalEngineering,MechanicalEngineering,ElectricalEngineering,FoodScience,Chemistrydepartmentsin5continents.Twoofthem(JasonKeithandZilinChen)nowholdendowedchairsandfiveofthem(JayneWu,DmitryKopelevich,AdrienneMinerick,ZachGagnonandSagnikBasuray)wereawardedtheNSFCareerAwardandthreearewomen.(Chia’sfirstPhDstudentin1984,M.Aluko,isanAfricanAmericanandisnowthePresidentofFederalUniversity,Nigeria.)Severalundergraduatestudentswhoworkedinhislab.arecurrentlyattopgraduate programs. His lab has regular visitors from foreign (National Chong Cheng, PekingUniv, Monterrey Tech, Imperial College, Swinburn, Moscow State in 2014) and US (Purdue,Naval Med Lab, Boston Univ in 2014) institutions. The expertise of these collaborators inMedicine, Physics, Mathematics, Chemistry and Engineering, is synthesized into innovativediagnosticdevicesatChia’slab.Chia believes that Precision and Personalized Diagnostics/Therapy cannot rely on just staticgenomic information but must rather depend on new home-use biotechnologies that canregularlymonitoranentirelibraryofbiomarkersanddiseasedcellsforspecificindividuals.Theproductsofthisnewsectormustbedesigned inaplatformformattoalloweasytailoringfordifferentindividualsandbiomarkers.Theplatformshouldleadtoaturn-keydevicethatcanbeused by an average consumer. Such a platform requires low-cost andmulti-plexmolecularmanipulation, detection and quantification technologies with unprecedented sensitivity andaccuracy.His lab is striving to realizemanyof these technologieswithnewmicro/nanofluidicphenomena and designs. Individual components of the platform are being developed bystartupsandamulti-nationalforeasy-entrymarketsinfoodsafety,contagiousdiseasecontrolandenvironmentalmonitoring.Theultimateaimis,however,tocatalyzeanewbiotechnologysector.

Lectureships ColburnLectureship,UniversityofDelaware,1988

JamesandCatherinePatternLectureship,UniversityofColorado,Boulder,1992.InvitedGeneralLectureatInternationalUnionofTheoreticalandAppliedMechanicsSymposiumonNonlinearInstabilityofNonparallelFlows,Potsdam,1993InvitedGeneralLectureatInternationalUnionofTheoreticalandAppliedMechanicsSymposiumonStructureandDynamicsofNonlinearWavesinLiquids,Hannover,Germany,1994.InvitedGeneralLectureatInternationalUnionofTheoreticalandAppliedMechanics.NonlinearSingularitiesinDeformationandFlow(Haifa,1997). KeynoteLecture,SecondJointUS/ChinaChemicalEngineeringConference,Beijing,May1997. Keynote Lecture, 13th International Congress of Chemical and Process Engineering

CHISA'98,Prague,August1998.StanleyCorrsinHydrodynamicsLecture,JohnsHopkins,March2002. KeynoteSpeaker,ASMEInternationalConferenceonMicro-channelsandMini-channels,

Rochester,June2004;Pohang,June2009. Keynote Speaker, Biomedical Engineering Society 2004 Annual Symposium, Tainan,

Taiwan,December,2004. KeynoteSpeaker,IndianaBiosensorSymposium,Indianapolis,April,2005. KeynoteLecturer,TheBianchiSessiononThinFilmsofSoftMatter,InternationalCenter

forMechanicalSciences,Udine,Italy,July2005. Keynote Lecturer, Annual Conference of the Society of the Korean Analytical Science

andTechnology,Mokpo,Korea,May,2006. Keynote Lecture, Advances in Microfluidics and Nanofluidics, Hong Kong, 2009;

Singapore,2011;Dalian,2012;NotreDame,2013;Taipei,2014;Beijing,2015. KeynoteLecturer,ACSColloidandInterfacialScienceSymposium,ColumbiaUniversity,

June2009. Keynote Lecture, ASME Mini/Micro/NanoChannels Conference, Pohang, Korea, June

2009. KeynoteLecture,Asian-PacificLabChipConference,Shanghai,October2009. InvitedSpeaker,WorkshoponElectrokinetics,IMA,UniversityofMinnesota,Dec2009.Keynote Lecturer, Second ASME Micro/Nanoscale Heat/Mass Transfer International

Conference,JiaotungUniversity,Shanghai,December2009. PlenaryLecture,WavePhenomenaIV,Edmonton,Canada,June2010. InvitedLecture,PhoresisWorkshop,Pohang,Korea,September2010. PlenarySpeaker,China-Japan-KoreaSymposiumonAnalyticalChemistry,Wuhan,2010. PlenarySpeaker,ElectrokineticsWorkshop,Haifa,Israel,December2010. KeynoteSpeaker,AMN-APLOC,Singapore,January,2011. PlenarySpeaker,ElectrokineticsWorkshop,ImperialCollege,London,2011.

Invited Speaker, Electrokinetics Symposium, APS-DFD Annual Meeting, Baltimore,November2011.

Keynote Speaker, International Conference of Applied Science, Opening of AppliedScienceDivisionBuilding,AcademiaSinica,Taiwan,October,2013.

KeynoteSpeaker,FoundationsofNanoScience,Snowbird,Utah,April,2014. InvitedLecturer,Dielectrophoresis2014,London,July2014. KeynoteSpeaker,China-GermanOpticalMedicalDevicesConference,Suzhou,Sept18-19,2014.

KeynoteSpeaker,TaiwanInstituteofChemicalEngineersAnnualMeeting,Taoyuan, Taiwan,Dec13,2014.

PlenarySpeaker,7thWACBEWorldCongressonBioengineering,Singapore,July6,2015. KeynoteandPlenaryLectures:SelectBioscience,MicrofluidicsCongressSanDiego,September2015,2016and2017;March,Boston,2017 KeynoteLecture,BionicsCenterPhDCongress,Budapest,Hungary,November2016. PlenaryLecture,AdvancesinPharmaceuticalAdvances,Wuhan,November2017..

Professional Activities OrganizedtheInternationalUnionofTheoreticalandAppliedMechaicsforSymposium

onNonlinearWaveBehaviorinMulti-PhaseFlow,July1999,NotreDame.AIChEChairofArea10d(AppliedMathematics)1994-1996. Panelist,NSF/EPAPartnershipforEnvironmentalResearch,1995;NSF(CTS)2001;2005. AdvisoryCouncil,ChemicalEngineeringDepartment,PrincetonUniversity,1996–2000. ScientificCommittee for InternationalUnionofTheoreticalandAppliedMechanics for

SymposiumonNonlinearSingularitiesinDeformationandFlow,March,1997atHaifa,Israel.

Scientific Advisory Committee of CHISA Congress on Nonlinear Dynamics in ChemicalandBioengineeringProcesses,Prague,August1998.

TechnicaladvisortotheMathematicsDepartment,InstituteofTechnologyatBundung,Indonesia,1997-98.

Organizing Committee, AnnualMeeting of American Physical Society-Division of FluidDynamics,NewOrleans,1999.

Established the Center forMicrofluidics andMedical Diagnostics at Notre Dame andfoundedstart-upMicrofluidicsApplicationsInc.,2003.

SteeringCommittee,IndianaBiosensorSymposium,2005. Steering Committee (founding member): Center for Advanced Diagnostics and

Therapeutics,UniversityofNotreDame.FoundedMFA,LLC(2004). AppointedScientificAdvisorofFCubed,LLC(2008).

Organizedandraisedfunds(US$60K)AdvancesinMicrofluidicsandNanofluidics,HongKong,January2009.

Raisedfunds(US$40K)andorganizedAdvancesinMicrofluidicsandNanofluidics2013,NotreDame.

AdvisoryCommittee,SecondASMEMicro/NanoscaleHeat/MassTransfer InternationalConference,JiaotungUniversity,Shanghai,December2009

FoundedtheAIPBiosciencesHorizonslectureseriesatNotreDame2018-?. Expertwitness:Irell-ManelaBioRadvs10xGenomics,2017-2018. Reviewer,OkinawaInstituteofScienceandTechnology,July2018.

Editorial Boards Chief and Founding Editor: Biomicrofluidics, AIP, 2006-present. (2015 Impact Factor:

3.56) Editorialboard:Membrane,2011-PresentAssociateEditor:SIAMJournalofAppliedMath,2000–2009AdvisoryBoardofActaMechanica,2003-2005International Journal of Bifurcation and Chaos in Applied Sciences and Engineering,

1990-1995

Patents

1.ProcessandApparatusforEnhancingIn-TubeHeatTransferbyChaoticMixing(withMihirSen),USPatent5,311,932(1994).Sequentialtwistingofaheatingcoilintwodifferentplanesenhancesheattransferbychaoticmixingactionof inertialDeanvortices.

2. Fast-igniting Catalytic Converters with Bypass (with David Leighton), United States

LettersPatent6,428,754 (2002).Aby-passdesign reduces theheat load intoacatalyticconvertersuchthatignitionoccursattheleadingedgeoftheconverterandtheheatofreactioncanbeprofitablyusedtolightofftheentireconverter.With the bypass, the converter lights off in less than a minute compared tothe10minutelight-offwithoutthebypass.

3. Method and Apparatus for Rapid Particle Manipulation and Characterization(with

ZacharyGagnon)USPatent7,744,738. (2010).A serpentinewiredesignallowshigh-field dielectrophoretic trapping and manipulation of cells, molecules andotherbioparticles.Thefieldissignificantlyhigherthanthatpossiblefordisjointelectrodepairstoachievemuchhighercaptureefficiency.

4.MethodsandApparatustoCaptureandReleaseMicrobeParticlesUsingAmino-

functionalizedSilica(withZilinChen,beingdevelopedbySMILLC,www.scientificmethods.com)USPatent7,960,180(2011).Silicabeadswithdifferentfunctionalizedsurfacegroupscantrapandreleasevirusindifferentbuffersduetopropertuningofdouble-layereffects.Thetechnologycanbeusedtocleanwaterorconcentratepathogensfordetection. 5.ACElectrospray,IonizationandElectrospinning(withLeslieYeo,Shau-ChunWang,ZachGagnonandDmitryLastochkin,preliminarylicensingagreementwithDolomite)USPatent8,267,914(2012).Anewhigh-frequencyACElectrospraying,dropletgenerationandelectrospinningtechnology.TheACconeExihibitsan11degreeangledifferentfromthe49degreesDCTaylorconeandproducessmallelectro-neutraldrops.ACfrequencyminimizesfieldandcurrentpenetrationandhenceenhancesmolecularandcellviability.ACelectrospinningprovidesmechanicallystrongmulti-fiberthreadsathighthroughputwithoutthewhippinginstabilityofDCelectrospinning,thusallowinghigh-throughputproduction.DigitalPCRandsingle-cellassaycanbedonewithdropletsgeneratedbyACsprayinoil.Thisnewdropletmicrofluidictechnologyismucheasiertotunethantheflow-focusingdropletgenerationtechnology.

6.RapidDetectionofViableBacteriaSystemandMethod(withShramikSenguptaandSachideviPuttaswamy.LicensedtoImpeDx,http://www.impedx.com/)USPatent8635028(2011).Arapiddielectrophoresisandimpedancemethodfordetectingbacteriaviabilitybyconcentratingandsensingbubblesgeneratedbytheantibioticallyscreenedbacteria.

7.MicrofluidicPlatformsforMulti-TargetDetecton(withJasonGordon,S.Senapati,ZachGagnonandSagnikBasuray.licensedtoFCubed,LLC,www.fcubed.bizcurrentlywith15employees).USPatent8771938(2014).Molecularhybridizationontoprobe-functionalizednanostructuressensitivelyaffectstheirpolarizabilityanddielectrophoreticmobility,allowingrapiddetectionofhybridizationeventsandmulti-plexdiagnosticsonbiochips.Thelargepolarizabilityandinducedfieldofcarbonnanotubesisusedtoassemblethemacrosselectrodesandtorapidlytrapanalytemoleculesfromaflowingsolution.

8. High-Frequency Alternating Current Electrospray Ion Source for Mass Spectrometry

(with David Go, Nishant Chetwani, Catherine Cassou) US Patent 8,716, 675(2014).ACelectrosprayisusedformassspectrometryapplications.ThemicrojetfromACspray,unlikeDCspary,doesnotdevelopaplumethatlosesmuchoftheanalyte. Hence, AC spray can be used without a sheath flow. AC sprayeddropletsareweaklychargedandhencecanachievesoftionization.ACspraycanalsopreferentiallyentrain low-mobilityanionsandofferameansofcontrollingthepHinthespraybytuningthefrequency.SincethechargestateofproteinsisafunctionofpH,thisoffersameansofproducinglargeanddistinctcharge/masssignals.

9. Microchamber Electrochemical Cell having a Nanoslot (with G. Yossifon, S. Basuray.

LicensedtoAgenDx,www.agendxbio.com,andtheFarEasternGroup)USPatent8,969,007 (2010).Weuseananoslot to achieveon-chip ionic strengthandpHcontrol and to concentrate nanoparticles or macromolecules for sensingapplications.Thenanoparticlescanbefunctionalizedwithprobessuchthattheirdielectrophoretic mobility change upon functionalization, thus achievingpreferentialtrappingandquantificationofhybridizednanoparticles.

10. MethodandApparatus forananopipetteBiosensor (withShoupengLiu,SSenapati,

YunshanWangandYuYan)USpatent9856518 (2014).Dancon, ananopipettebiosensorcapableofdetectingasmallconcentrationoftargetmoleculeswithina sample solution using optical detection methods. The biosensor includes ananopipette that connects a nanocolloid reservoir containing a nanocolloidsolution and a sample reservoir containing a sample solution, where thenanopipette is tapered at the end connected to the sample reservoir. ThenanocolloidsolutionincludesnanoparticlesfunctionalizedwithprobesspecifictomiRNAofthetargetmoleculesandreporters.Duringthedetectionprocess,thenanocolloidsnanoparticlesaggregatesuchthatplasmonichotspotsareformed.These hotspots magnify the reporter signals produced when the probeshybridizewithtargetmolecules.

Pendingpatents:

1. NanoporousMembraneBiosensor(withZdenekSlouka,S.SenapatiandL-JCheng,

licensedtoAgenDxLLCwww.agendxbio.com)Chargedmoleculesandionscanbeconcentrateda-millionfoldforeasierdetectionbyexploitinginternalandexternalconcentrationpolarizationofnanoporousgranule/membrane/nanoslottoelectrophoreticallyand

dielectrophoreticallyaccumulatetheanalyte.Chargeinversionuponhybridization is used to produce PN type surface junctions and amplify ion

currentsignalsformoleculardetection.

2. ChipScalepHActuationUsingabipolarnanoporousmembrane,weareabletoproduceaveryhigh fieldatthePNjunctiontobreakwaterdirectlywithaDCfield.Bycombiningtheprotonsandhydroxyleionsfromdifferentbipolarmembranes,wecanchangepHrapidlyandpreciselywithalargedynamicrangeof2to10.AlinearpHgradientcanalsobesustainedonachiptoallowhigh-throughputcontinuousisoelectricfocusing.PrecisepHactuationallowsustoregenerated biosensorsandtoenhanceselectivity.

3. Silicon-BasedNanofluidicIonCurrentMemristor.ASi-Silicatransitionallowsus

tobuildamemristorthatoperatesdynamicallywithaperiodicinput.Importantly,thememristorcanoperateinliquid,thusallowingthesynthesisofanioniccircuitthatcouldbeusedforbiosensingandforcommunicatingwithcellcommunitiesandneuronnetworks.

4. ACElectrosprayedDropletsforDigital/EmulsionPCR.Wespraywatersolutionsinoilatarateofonebilliontoonetrilliondropletsperhourandwithamonodisperseddropletsizethatcanbetunedbetweensubmicronto50microns.Themicroemulsionisbestusedfordigital/emulsionPCRandcanoutperformthecurrentflow-focusingdropletgenerationmethodbyordersofmagnitudeinthroughputwithcomparablesizecontrol.High-throughputnanoemulsionisalsousefulfordrugencapsulationanddelivery.(PreliminarylicensingagreementwithDolomite.)

5. AShear-EnhancedCNTNanoassemblyNanosensorPlatform.WeassemblesingleCNTsacrossparallelelectrodesandestimatethenumberofCNTsfromconductancemeasurementswithsingleCNTresolution.AsandwichELISAschemeforproteinbiomarkers,withantibodiesonboththeCNTandelectrodes,thenachievessensitivitydownto100copiesofprotein,roughlythenumberfromasingletumorcell.WethenusehydrodynamicshearandthelargeStokesdragofthehighaspectratiooftheCNTtoachieveselectivitysothatHer2,ERandPRproteins,breastcancerbiomarker,canbedifferentiatedfromitsisoformswithsimilardissociationconstants.

Press Highlights

.PhysicsNewsin1992,“ChaoticMixinginFluidFlows”,pg50,1992..TheEconomists,“ScienceandTechnology-BalancingBroomsticks”,pg.95,June25th,1994..AmericanPhysicalSocietyNews,“PatternsonFallingFilms”,pg.S14,April1995..ChemicalEngineeringProgress,“CatalyticConverterFeaturesQuickLightoff”,pg15,May2001..IndianaBusinessMagazine,“BiosensorTechnologyinIndiana”,March,2005..BioscienceTechnology,“MicrofluidicAnalyzers:Slow,SteadyProgress”,October,2005..“Einstein’sTeaLeaves”onformerpost-docLeslieYeo’sworkatNotreDameDiscoveryChannel(Jan19,2007),TheEconomists(Jan20,2007).“ChannelingMicrofluidicDevicesintoPoint-of-CareDiagnostics”,MedicalProductManufacturingNews,June2010..“FightingforInnovativeHealthCare”,NBC-NotreDame,nationalTV,2010.https://www.nd.edu/fighting-for/2010/fighting-for-innovative-healthcare/.ChicagoSunTimesNov16,2012“EnteringNewWaterwithTinyChips”onstartupFCubed

http://www.fcubed.biz/Entering-new-waters-via-tiny-chip.InsideIndianaBusinessAug28,2012“ResearchersCreatingTestsforSaferMilk”http://www.insideindianabusiness.com/incubate-indiana.asp?ID=1984&Detail=True.RuralTVJuly31,2012“MilkTest”onGroup’sBrucelladetectiontechnology.NanDiowins$150,000CardinalChallengeforanOralCancerDiagnosticDevicehttp://news.nd.edu/news/46393-notre-dame-team-wins-top-honors-in-20 cardinal-challenge/.SouthBendTribunearticleaboutjobmarketsatSouthBendandtheadditionaljobsFCubedbroughttoSouthBend: http://www.southbendtribune.com/app/economy/.NationalScienceFoundationDiscoveryWebsiteaboutGroup’seffortsontechtransfer:http://www.nsf.gov/discoveries/disc_summ.jsp?cntn_id=133201&org=NSF

Publications

Books “IUTAMSymposiumonNonlinearWavesinMulti-PhaseFlow”,KluwerAcademicPress,

2000.“ComplexWaveDynamicsonThinFilms”(withEvgenyA.Demekhin),ElsevierScientific

Press,2002.(465citations)“Electrokinetically DrivenMicrofluidics and Nanofluidics” (with Leslie Yeo), Cambridge

UnivPress(2009).(198citations)JournalPublicationsandBookChapters

(Hfactor:64,~13,000totalcitations,~800citations/year;GoogleScholar)FluidMechanics:PhysFluid(18papers),JFM(12),PRL(12),PRE(12),JCIS(6)SIAMJAppMath(3),PhilTransRoyalSoc(2),AnnualReviewofFluidMech(2)Micro-Nanofluidics:Biomicrofluidics(18),Electrophoresis(10).LabChip(7),JCP(10),JPC(3)AdvMaterials(2),ACSNano(2),Biosensors&Bioelectronics(4),Small(2),Annual

ReviewofAnalyticalChem(1),AnalyticalChemistry(2)ReactionEngineering/Control:ChemEngSci(25),AIChEJ(10)1. Oka, M., Chang, H.-C. and Gavalas, G. R., "Computer-Assisted Molecular Structure

ConstructionforCoal-DerivedCompounds,"Fuel,561(1977).(35citations)2. Chang,H.-C.andWeinberg,W.H.,"ModulatedMolecularBeamMassSpectrometry:A

GeneralizedExpressionforthe 'ReactionProductVector' forLinearSystems,"J.Chem.Phys.,66,No.9,4176(1977).

3. Chang, H.-C. andWeinberg,W. H., "An Analysis ofModulatedMolecular BeamMass

SpectrometryAppliedtoCoupledDiffusionandChemicalReaction,"SurfaceScience,65,153(1977).

4. Chang, H.-C. and Weinberg, W. H., "An Analysis of Modulated Molecular Beam Mass

SpectrometryAppliedtoNonlinearSystem,"SurfaceScience,72,617(1978).5. Chang,H.-C. andWeinberg,W.H., "ModulatedMolecularBeamScattering fromSolid

Surfaces:thePulseTestingMethodofAnalysis,"ApplicationofSurfaceScience,3,168(1979).

6. Chang, H.-C. and Calo, J. M., "Exact Criteria for Uniqueness and Multiplicity via a

CatastropheTheoryApproach,"Chem.Eng.Sci.,34,285(1979).(54citations)

7. Chang,H.-C.andCalo,J.M.,"APrioriEstimationofChemicalRelaxationOscillationsViaaSingularPerturbationTechnique,"Chem.Eng.Commun.,3,431(1979).

8. Chang, H.-C. and Calo, J.M., "Regions ofMultiplicity for VariousModels of Chemical

Reactors,"Chem.Eng.Sci.,35,264(1980).9. Chang,H.-C.andCalo,J.M.,"ExactUniversalCriteriafortheAdiabaticTubularPacked

BedReactor,"Chem.Eng.Sci.,35,1611(1980).10. Chang, H.-C. and Aluko,M., "A Quasi-Steady State Analysis of the Dynamics of Two-

SpeciesHeterogeneousCatalyticReactions,"Chem.Eng.Sci.,36,1611(1981).11. Chang, H.-C. and Calo, J.M., "Analysis of Radial Flow Packed Bed Reactors--How Are

TheyDifferent?" in"ChemicalReactors", H.S.Fogler,ed.,ACSSymposiumSeries,168(1981).

12. Chang,H.-C."ANon-FickianModelofPackedBedReactors,"AIChEJ.,28,208(1982).13. Aluko,M., andChang,H.-C., "Multiplicity,Uniqueness and Stability for an Exothermic

Reaction in a Non-Adiabatic Bubble Column Reactor," Chem. Eng. J., 24, No. 2, 151(1982).

14. Chang, H.-C., and Aluko, M., "Comment on the Model for Isothermal Oscillations of

EthyleneOxidationonPlatinum,"J.ofCatal.,73,198(1982).15. Chang, H.-C., "Multi-Scale Analysis of Effective Transport in Periodic Heterogeneous

Media,"Chem.Eng.Commun.,15,83(1983).16. Chang,H.-C.,Saucier,M.andCalo,J.M.,"ADesignCriterionforRadialFlowFixedBed

Reactors,"AIChEJ.,29,1039(1983).17. Chang,H.-C.,"TheDomainModelforHeterogeneousCatalysis,"Chem.Eng.Sci.,38,535

(1983).18. Chang, H.-C., "Effective Diffusion and Conduction in Two-Phase Media - A Unified

Approach,"AIChEJ.,29,846(1983).19. Benzoni,J., and Chang, H.-C., "Effective Diffusion in Bidisperse Media - An Effective

MediumApproach,"Chem.Eng.Sci.,39,161(1984).20. Chang, H.-C., and Aluko, M., "Multi-Scale Analysis of Exotic Dynamics in Surface

CatalyzedReactions-I.JustificationandPreliminaryModelDiscrimination,"Chem.Eng.Sci.,39,37(1984).

21. Aluko, M., and Chang, H.-C., "Multi-Scale Analysis of Exotic Dynamics in SurfaceCatalyzed Reactions - II. Quantitative Parameter Space Analysis of an ExtendedLangmuir-HinshelwoodReactionScheme,"Chem.Eng.Sci.,39,51(1984).

22. Chen, L.-H., and Chang, H.-C., "Global Stabilization of a Biological Reactor by Linear

FeedbackControl,"Chem.Eng.Comm.,27,231(1984).23. Chang, H.-C. and Chen, L.-H., "Bifurcation Characteristics of Nonlinear SystemsUnder

ConventionalPIDControl,"Chem.Eng.Sci.,39,1127(1984).24. Aluko,M., and Chang,H.-C., "PEFLOQ: AnAlgorithm for the Bifurcational Analysis of

PeriodicSolutionsofAutonomousSystems,"Comp.andChem.Eng.,8,355(1984).25. Chang, H.-C., "Several paths to Chaos in a Stiff COOxidation System" in "Frontiers in

Chemical Reaction Engineering", L. K. Doraiswamy and R. A. Mashelkar, eds., WileyEasternLtd.(1984).

26. McDermott, P., Bonvin, D.,Mellichamp,D. and Chang,H.-C., "Eigenvalue Spectra and

Modal Contributions for Counterflow Reactor Models," Chem. Eng. Comm., 31, 263(1984).

27. McDermott,P.,andChang,H.-C.,"OntheGlobalBehaviorofanAuto-ThermalReactor

StabilizedbyLinearFeedbackControl,"Chem.Eng.Sci.,39,1347(1984).28. Lahbabi, M. and Chang, H.-C., "High Reynolds Number flow Through Cubic Arrays of

Spheres--Steady-State Solution andTransition to Turbulence, "Chem.Eng. Sci., 40, 435(1985).

29. McDermott, P. E., Chang, H.-C. and Rinker, R. G., "Experimental Investigation of

Controller-InducedBifurcationsinaTubularReactor,"Chem.Eng.Sci.,40,1355(1985).30. Chen,L.-H.andChang,H.-C.,"NonlinearStabilityofaBubbleColumnReactor,"Chem.

Eng.J.,3D(2),103(1985).31. Chen, L.-H. and Chang, H.-C., "Global Effects of Controller Saturation on Closed-Loop

Dynamics,"Chem.Eng.Sci.,40,2191(1985).32. Aluko, M. and Chang, H.-C., "The Stability and Oscillations of Carbon Monoxide

OxidationoverPlatinumSupportedCatalyst:EffectofButene,"Chem.Eng.Sci.,40,2389(1985).

33. Aluko, M., and Chang, H.-C., "Dynamic Modelling of a Heterogeneously - Catalyzed

systemwithStiffHopfBifurcation,"Chem.Eng.Sci.,41,317(1986).

34. Chang, H.-C., "Recent Developments in the Dynamics of Heterogeneous CatalyticReactions,"chapterin"DynamicsofNonlinearSystems,"EditorV.Hlavacek,GordonandBreachConceptsinChemicalEngineeringSeries,(invitedreview)Chap.3,85(1986).

35. Hwang,S.-H.andChang,H.-C., "ProcessDynamicModels forHeterogeneousChemical

Reactors - An Application of Dynamic Singularity Theory," Chem. Eng. Sci., 41, 953(1986).

36. Chang,H.-C., "NonlinearWaveson Liquid FilmSurfaces, I. Flooding in vertical Tubes,"

Chem.Eng.Sci.,41,2463(1986).37. Chen, L.-H.andChang,H.-C., "NonlinearWavesonLiquidFilmSurfaces, II.Bifurcation

AnalysesoftheLong-WaveEquations,"Chem.Eng.Sci.,41,2477(1986).38. Lahbabi, M. and Chang, H.-C., "Flow in Periodically Constricted Tubes: Transition to

InertialandNonsteadyFlows,"Chem.Eng.Sci.,41,2487(1986).39. Chang, H.-C., "Traveling Waves on Fluid Interfaces - Normal Form Analysis of the

Kuramoto-SivashinskyEquation,"ThePhysicsofFluids,29,3142(1986).40. Chang,H.-C.andChen,L.-H.,“GrowthofaGasBubbleinaViscousFluid,”ThePhysicsof

Fluids,29,3530(1986).41. Chang,H.-C.,“EvolutionofNonlinearWavesonVerticallyFallingFilms–ANormalForm

Analysis,”Chem.Eng.Sci.,42,515(1987).42. Hwang,S.-H.andChang,H.-C.,“TurbulentandInertialRollWavesinInclinedFilmFlow”,

ThePhysicsofFluids,30,1259(1987).43. Hwang,S.-H.andChang,H.-C.,“ATheoreticalExaminationofTuningMethodsforSimple

Regulators,”Chem.Eng.Sci.,42,2395(1987).44. Chen, L.-H. and Chang, H.-C., “Equilibrium Shapes of Liquid Bridges Under Gravity-

Symmetry Breaking and Imperfect Bifurcations of Two-Dimensional Bridges,” J. ofColloil.AndInterfaceSci.,120377(1987).

45. Saucier, M. F., Chang, H.-C. and Seborg, D. E., “Bifurcation Analysis of Multivariable

FeedbackControlSystem”,Chem.Eng.Comm.,57,215(1987).46. Ho,K.L.andChang,H.-C.,“OnNonlinearDoublyDiffusiveMarangoniInstability”,AIChE

J.,34,705(1988).47. Ratulowski, J. and Chang, H.-C., “SnapOff at Strong Constrictions: The Effect of Pore

Geometry and Surfactant Concentration”, Chap. 14 in “Surfactant-Based Mobility

Control: Progress inMiscible-Flood EnhancedOil Recovery”, pg 282,D.H. Smith ed.,AmericanChemicalSociety,DC(1988).

48.Lu,W.Q.andChang,H.-C.,“ABoundaryIntegralStudyofBubbleFormationandTransport

inChannelsFilledwithViscousFluid”,J.Comp.Physics,77,340(1988).49. Boe, E., Hwang, S.-H. and Chang, H.-C., “Controller Tuning Based on Cross Over

Information”,JCIChE,19,359(1988).50. Boe, E. and Chang, H.-C., “Dynamics of Delayed Systems Under Feedback Control”,

Chem.Eng.Sci.,44,1281(1989).51. Hwang, S.-H. and Chang, H.-C. “Non-Boussinesq Effects on Transitions in Hele-Shaw

Convection”,ThePhysicsofFluids,1,924(1989).52. Chang,H.-C.,“OnsetofNonlinearWavesonFallingFilms”,ThePhysicsofFluids,1,1314

(1989).(73citations)53. Ratulowski,J.andChang,H.-C.,“TransportofGasBubblesinCapillaries”,ThePhysicsof

Fluids,1,1642(1989).(192Citations)54. Ratulowski,J.andChang,H.-C.,“TheEffectofSurfactantTransportontheMotionofGas

BubblesinCapillaries”,JournalofFluidMech.,210,303(1990).(196Citations)55. Chang,H.-C., “FundamentalProcessControlbyD.M.PrettandC.E.Garcia”– Invited

Review,AmericanScientist,78,74(1990).56. Cheng, M. and Chang, H. – C., “A Generalized Sideband Stability Theory via Center

ManifoldProjection”,ThePhysicsofFluids,2,1364(1990).57. Chiao,S.-M.andChang,H.-C.,“InstabilityofaCEFFluidinaDisc-and-CylinderSystem”,

JournalofNon-NewtonianFluidMech.,36,361(1990).58. Prokopiou, T., ChengM. and Chang, H.-C.,”Integral Boundary Layer Theory of Finite-

Amplitude Waves on Inclined Films”, Journal of Fluid Mech., 222, 665 (1991). (115citations)

59. Boe,E.andChang,H.-C.,“TransitiontoChaosfromaTwo-TorusinaDelayedFeedback

System”,Int.J.ofBifurcationandChaos,1,67(1991),(InauguralIssue).60. Chen, C. C., Lahbabi, A., Chang, H.-C. and Kelly, R. E., “Spanwise Pairing of Finite-

Amplitude Longitudinal Vortex Rolls in Inclined Free Convection Boundary Layers”,JournalofFluidMech.,231,73(1991).

61. Cheng,M.andChang,H.-C.,“LongWavesonInclinedFilmsatHighReynoldsNumbers”,JofFluidMechanics,222,665-691(1991).

62. Cheng, M. and Chang, H.-C., “Subharmonic Instability of Finite-Amplitude

MonochromaticWaves”,ThePhysicsofFluids,4,505(1992).63. Ghosh, S., Chang, H.-C and Sen, M., “Heat Transfer Enhancement due to Slender

Recirculation and Chaotic Transport Between Counter – Rotating Eccentric Cylinder”,JournalofFluidMech.,238,119(1992).

64. Chang,H.-C.andSen,M.,“ChaoticMixingforHeat-TransferEnhancement”,pg175-188

in“AppliedChaos”,EditorsJ.H.KimandJ.Stringer,JohnWiley(1992).65. Cheng,M.andChang,H.-C., “StabilityofAxisymmetricWavesonLiquidFilmsFlowing

DownaVerticalColumntoAzimuthalandStreamwiseDisturbance”,Chem.Eng.Comm.,118,327(1992)(SpecialIssueinhonorofS.G.Bankoff.)

66. Sangalli,M.,Prokopiou,T.,McCready,M.J.andChang,H.-C.,“ObservedTransitions in

Two-PhaseStratifiedGas-LiquidFlow”,Chem.Eng.Sci.,47,3289(1992).67. Chen, C.-C. and Chang, H.-C., “Accelerated Disturbance Damping of an Unknown

DistributedSystembyNonlinearDominant-ModeFeedback”,AIChEJ.38,1461(1992).68. Chen,C.C.,Lahbabi,A.,Chang,H.-C.andKelly,R.E.,“OntheSubharmonicInstabilityof

Finite-Amplitude Longitudinal Vortex Rolls in Inclined Free Convection BoundaryLayers”,pg289-296in“OrderedandTurbulentPatternsinTaylor-CouetteFlow”,EditorsC.D.AndereckandF.Hayot,NATOASISeriesB:Phys.297(1992).

69. Chang, H.-C., “Flow of Gas Slugs Under Microgravity Conditions”, pg 261 in

“Hydromechanics and Heat/Mass Transfer in Microgravity”, Gordon and Breach (1992). 70. Acharya,N.,Sen,M.andChang,H.-C.,“HeatTransferEnhancementinCoiledTubesby

ChaoticMixing”,InternationalJ.ofHeatandMassTransf.,35,2475-2489(1992).(103citations)

71. Chang,H.-C.,Demekhin,E.A.andKopelevich,D.I.,“NonlinearEvolutionofWavesona

FallingFilm”,J.FluidMech.,250,433-480(1993).(190citations)72. Chang,H.-C.,Demekhin,E.A.andKopelevich,D.I.,“LaminarizingEffectsofDispersionin

anActive-DissipativeNonlinearMedium’,PhysicaD.,63,299-320(1993).73. Chen,C.-C.,Wolf,E.E.andChang,H.-C.,“Low-DimensionalSpatio-TemporalDynamics

onNon-UniformCatalyticSurfaces”,J.Phy.Chem.,97,1055(1993).

74. Chang,H.–C.,Demekhin,E.A.andKopelevich,D.I.,“ConstructionofStationaryWavesonaFallingFilm”,ComputationalMech.,11,313-322(1993).

75. Indeikina,A.andChang,H.-C.,“EffectiveDiffusioninTime-PeriodicLinearPlanarFlow”,

ThePhysicsofFluids,A5,2563-2566(1993).76. Chang,H.-C.,“WaveEvolutiononaFallingFilm”,AnnualReviewofFluidMechanics,26,

103-136(1994).(465citations)77. Kalliadasis, S. and Chang, H.-C., “Drop Formation during Coating of Vertical Fibers”,

JournalofFluidMechanics,261,135-168(1994).78. Acharya,N.,Sen,M.andChang,H.-C.,“ThermalEntranceLengthandNusseltNumbers

inCoiledTubes”,InternationalJ.ofHeatandMassTransf.,37,336-340(1994).79. Kalliadasis,S.andChang,H.-C.,“ApparentDynamicContactAngleofanAdvancingGas-

LiquidMeniscus”,ThePhysicsofFluids,6,(1),12-23,(1994).80. Qin,F.,Wolf,E.E.andChang,H.-C.,“ControllingSpatio-TemporalPatternsonaCatalytic

Wafer”,Phys.Rev.Lett.,72,1459-1462(1994).81. Chang, H.-C., Cheng,M., Demekhin, E. and Kopelevich, D. I., “Secondary and Tertiary

ExcitationofThree-DimensionalPatternsonaFallingFilm”,J.FluidMech.,270,251-275(1994).

82. Sangalli, M. and Chang, H.-C., “Complex Spatiotemporal Patterns in an Open-Flow

Reactor”,Phys.Rev.E.,49,5207-5217(1994).83. Chang, H.-C., Review of “Chaotic and Fractal Dynamics: An Introduction for Applied

ScientistsandEngineers”,byFrancisC.Moon,AIChEJ,40,1924-1925(1994).84. Chang,H.-C.andSen,M., “ApplicationofChaoticAdvection toHeatTransfer”,Chaos,

SolitonsandFractals,4,955-975(1994).85 Chiao,S.-M.andChang,H.-C., “PerforationandPerforatorAnalysis–AnApplicationof

FiltrationTheory,”J.ChineseInst.Chem.Eng.,25,279-305(1994).86. Chang, H.-C., M. Cheng, E. Demekhin and E. N. Kalaidin, “Quasi-Stationary Wave

EvolutiononaFallingFilm”,pg407-424in“NonlinearInstabilityofNonparallelFlows”,S.P.Lin,W.R.C.PhillipsandD.T.Valentine(Eds.),Springer-Verlag,1994.

87. M. Sen and Chang, H.-C., “Chaotic Particle Paths and Heat Transfer Enhancement in

InternalFlows,”pg397-400,in“TowardstheHarnessingofChaos,”M.Yamaguti(Eds.)Elsevir,1994.

88. Leighton,D.T.andChang,H.-C.,“ATheoryforFast-IgnitingCatalyticConverters”,AIChE

J,41,1898-1915(1995).89. Cheng, M. and Chang, H.-C., “Competition between Subharmonic and Sideband

SecondaryInstabilitiesonFallingFilm”,Phys.Fluid,7,34-54(1995).90. Balakotaiah, V. and Chang, H.-C., “Dispersion of Chemical Solutes in Chromatographs

andReactors”,Phil.TransoftheRoyalSocietyofLondon,A351,39-75(1995).91. Chang,H.-C.,Demekhin,E.A.andKalaidin,E.N.,”InteractionDynamicsofSolitaryWaves

onaFallingFlim”,J.FluidMech.,294,123-154(1995).92. Sangalli,M.,Gallagher,C.T.,Leighton,D.T.,Chang,H.-C.andMcCready,M.J.,“Finite-

AmplitudeWavesat the InterfacebetweenFluidswithDifferentViscosity”,Phys.Rev.Lett.,75,77-80(1995).

93. Chang,H.-C.,Demekhin,E.A.andKopelevich,D.I.,“StabilityofaSolitaryPulseAgainst

WavePacketDisturbancesinanActiveMedium,”Phy.Rev.Lett.,75,1747-1751(1995).94. Chang,H.-C. andDemekhin, E.A., “RepulsiveDynamicsof SolitaryPulses,pg24-41 in

“Structure and Dynamics of Nonlinear Waves in Fluids”, Adv. Series in NonlinearDynamics,Vol.7,A.MielkeandK.Kirchgässner(Eds.),WorldScientific(1995).

95. Chang,H.-C. andDemekhin, E. A., “SolitaryWave Formation andDynamics on Falling

Films”,Adv.InAppliedMech.,32,1-58(1995).96. McCready,M. J. and Chang, H.-C., “Formation of Large Disturbances on Sheared and

FallingLiquidFilms”,Chem.Eng.Comm.,141,347(1996). (SpecialIssueinMemoryofA.E.Dukler).97. Chang,H.-C.,Demekhin,E.A.andKalaidin,E.,“SimulationofNoise-DrivenDynamicson

aFallingFilm”,AIChEJ.,42,1553-1568(1996).98. Chang,H.-C.,Demekhin,E.A.andKalaidin,E.,“Scalings,Self-SimilarityandStatisticsof

InterfacialTurbulenceonaFallingFilm”pg86-111 in“Advances inMulti-PhaseFlow”,Editors,Y.Y.Renardy,A.V.Coward,D.T.PapageorgiouandS.M.Sun,SIAM(1996).

99. Chang,H.-C.,Demekhin,E.A.,Kalaidin,E.andYe,Y.,“CoarseningDynamicsofFalling-

FilmSolitaryWaves”,Phys.Rev.E,54,1467-1478(1996).100. Chang, H-C., Demekhin, E. A. and Kopelevich, D. I. “Local Stability Theory of Solitary

PulsesinanActiveMedium”,PhysicaD.,97,353-375(1996).

101. Kalliadasis,S.andChang,H.-C.,“EffectsofWettabilityonSpreadingDynamics”,IECRes,

SpecialIssueinHonorofE.Ruckenstein,35,2860(1996).102. Chang, H.-C., Demekhin, E.A, Kalaidin, E. and Y. Ye, “Scalings of Spatio-Temporal

DynamicsonaFallingFilm”,PhysicaScripta,67,67-72(1996).103. Bandyopadhyay, S., Miller, A. E., Chang, H.-C., Banerjee, G., Yuzhakov, V., Yue, D.-F.,

Ricker, R. E., Jones, J., Eastman, J. A., Baugher, E. and Chandrasekhav, M.,“ElectrochemicallyAssembledQuasi-PeriodicQuantumDotArrays”,Nanotechnology,7,360-372(1996).(192citations)

104. Sawyer,D.R.,Sen,M.andChang,H.-C.,“EffectofInterfacialStretchingonBimolecular

ChemicalReactioninHelical-CoilReactors”,Chem.Eng.J.64,129-142(1996).105. Indeikina,A.,Veretennikov,I.andChang,H.-C.,“DropFallofffromPendentRivulets”,J.

FluidMech.,338,173-201(1997).106. Sangalli,M.,McCready,M.J.andChang,H.-C.,“StabilizationMechanismofShortWaves

inStratifiedGas-LiquidFlow”,Phys.Fluids,9,919(1997).107. Chang, H.-C., Demekhin, E. A., Kopelevich, D. I. and Ye, Yi “Nonlinear Wavenumber

SelectioninGradient-FlowSystems”,Phys.Rev.E.,55,2818(1997).108. Yuzhakov, V. V., Chang, H.-C. and Miller, A. E., “Pattern Formation during

Electropolishing”,Phys.RevB,56,12608(1997).(127citations)109. Chang,H.-C.,Demekhin,E.A.andKalaidin,E.,“GenerationandSuppressionofRadiation

by Solitary Pulses” Pgs 17-51 in “Differential Equations –– Theory, Numerics andApplications”,EditorsE.vanGroessenandE.Soewono,Kluwer(1997).

110. Orlychenko,O.,Ye,Y.andChang,H.-C., “Front InteractiononaRingElectrode”,Phys.

Rev.E.,57,5196(1998).111. Chang,H.-C.,Demekhin,E.A.andKalaidin,E.,“GenerationandSuppressionofRadiation

bySolitaryPulses”,SIAMJ.onAppliedMath.,58,1246(1998).112. Veretennikov, I., Indeikina, A. and Chang, H.-C., “Front Dynamics and Fingering of a

DrivenContactLine”,J.FluidMech.,373,81(1998).113. Sawyers, D. R. , Sen, M. and Chang, H.-C., “Heat Transfer Enhancement in Three-

DimensionalCorrugatedChannelFlow”,Int.J.ofHeatandMassTransf,41,3559(1998).

114. Indeikina,A.andChang,H.-C.,“AMolecularTheoryforDynamicContactAngles”,pg34-338in“NonlinearSingularitiesinDeformationandFlow”,Editors:D.DurbinandJ.R.A.Pearson,Kluwer(1999).

115. Chang,H.-C. andDemekhin, E. A., “CoalescenceCascade towardsDrop Formation”, J.

FluidMech.,380,233(1999).116. Keith, J.M. Leighton,D.T.andChang,H.-C., “aNewDesignofReverse-FlowReactors

WithEnhancedThermalDispersion”,Industrial&Eng.Chem.Res.,38,667(1999).117. Yuzhakov,V.V.,Takhistov,P.V.,Miller,A.E.andChang,H.-C.,“PatternSelectionDuring

ElectropolishingduetoDouble-LayerEffects”,Chaos,9,62(1999).118. Chang,H.-C.,Demekhin,E.A.andKalaidin,E.,“IteratedStretchingofViscoelasticJets”,

Phys.Fluids,11,1717(1999).119. Veretennikov, I., Agarwal, A., Indeikina, A. and Chang, H-.C., “Unusual Contact-line

DynamicsofThickFilmsandDrops”,J.ofColloidandInterfaceScience,215,425(1999).120. Kopelevich, D. I. and Chang, H.-C., “Nonequilibrium Diffusion in Zeolites due to

DeterministicHamiltonianChaos”,PhysRev.Lett.,83,1590(1999).121. YeY.andChang,H.-C.,“ASpectralTheoryforFingeringonaPrewettedPlane”,Physics

ofFluids,11,2494(1999).122. Chang,H.-C.,Demekhin,E.A.,Roberts,R.M.andYe,Y.“ModulationWaveDynamicsof

Kinematic InterfacialWaves”,pgs99-112 in“FluidDynamicsat Interfaces”,Editors:WShyyandR.Narayanan,Cambridge(1999).

123. Robert,R.M.,Ye,Y.,Demekhin,E.AandChang,H.-C., “WaveDynamics inTwo-Layer

CouetteFlow”,ChemicalEngineeringScience,55,345(2000).124. Roberts, R. M. and Chang, H.-C., “Wave Enhanced Interfacial Transfer”, Chemical

EngineeringScience,55,1127,(2000).125. Arya,G.,Maginn,E. J.andChang,H.-C.,“EfficientViscosityEstimationfromMolecular

DynamicsSimulationviaMomentumImpulseRelaxation”,J.ofChem.Phys.,113,2079,(2000).

126. Chang,H.-C.,Demekhin,E.A.andKalaidin,E.,“CoherentStructures,Self-Similarity,and

UniversalRollWaveCoarseningDynamics”,Phys.OfFluids,12,2268(2000).127, Chang, H.-C., Demekhin, E. A. and Takhistov, P. V., “Circular Hydraulic Jumps

TriggeredbyBoundaryLayerSeparation”,JournalofColloidandInterfaceScience,233,329(2001).128. Kopelevich,D.I.AndChang,H.-C.,“Doeslatticevibrationdrivediffusioninzeolite?”,

JournalofChemicalPhysics,114,3776(2001).129 Keith,J.M.,Chang,H.-C.andLeighton,D.T.,“DesigningaFast-IginitingCatalyticConverterSystem”,AIChEJ,47,650(2001).130 Arya,G.,Maginn,E.J.andChang,H.-C.,“EffectoftheSurfaceEnergyBarrieronSorbateDiffusioninAlPO4-5”,J.Phys.Chem.,105,2725(2001).131 Acharya,N.,Sen,M.andChang.H.-C.,“Analysisofheattransferenhancementincoiled-

tubeheatexchangers”,InternationalJ.ofHeatandMassTransfer,44,3189-3199(2001)132 Chang,H.-C.,“Bubble/DropTransportinMicrochannels”,pg11-15,“TheMEMSHandbook”Editor;M.Gadelhak,CRCPress(2001).(951citations)133 Arya,G.,Chang,H.-C.andMaginn,E.J.,“Acriticalcomponentofequilibrium,non-equilibriumandboundary-drivenmoleculardynamicstechniquesforstudyingtransportinmicroporousmaterial”,J.ofChemPhys,115,8112(2001)(149citations)134 Kopelevich,D.I.andChang,H.-C.,“Diffusionofinertgasesinsilicasodalite:importanceoflatticeflexibility”,J.ofChemPhys.,115,9519(2001)135. Thamida,S.K.,Takhistov,P.V.andChang,H.-C.,“Fractaldewettingofaviscous

FilmBetweenSeparatingParallelPlates”,PhysofFluids,13,2190(2001).136 Takhistov,P.,IndeikinaA.andChang,H.-C.,“ElectrokineticdisplacementofairbubblesInmicrochannels”,PhysofFluids,14,1(2002).137 Ben,Y.andChang,H.-C.,“ASpectralTheoryforMiscibleFingering”,PhysofFluids,14,999(2002).138 Thamida,S.andChang,H.C.,“MechanismofNanoporousPatterningDuringAnodization”,Chaos,12,240(2002).(109citations)139 Pacheco-Vega, A., Franco, W. , Chang, H.-C. and Sen, M. “Nonlinear Analysis of Tilted ToroidalThermosyphonModels”,InternationalJournalofHeatandMassTransfer,45,No.7,1379-1391(2002).140 Minerick,A.,Ostafin,A.andChang,H.-C.,“ElectrokineticTransportofRedBloodCellsInMicrocapillaries”,J.ofElectrophoresis,23,2165(2002).

141 Indeikina,A.andChang,H.-C.,“EstimateofTurbulentEddyDiffusivitybyExactRenormalization”,SIAMJAppMath,63,1(2002).142 Ben,Y.andChang,H.-C.,“NonlinearSmoluchowskiSlipVelocityandVortexGeneration”,J.FluidMech.,461,229-238(2002).(133citations)143 Ben,Y.,Takhistov,P.,Demekhin,E.A.andChang,H.-C.,“MiscibleFingeringinElectrokineticFlow”,J.oftheChineseInstituteofChemicalEngineers,FestschriftissueinhonorofDr.NormanLi,33,No.1,15(2002).144 Chang,H.-C.,Demekhin,E.A.andSaprikin,S.S.,“Noise-drivenwavetransitionsona

Verticallyfallingfilm”,J.FluidMech.,462,255-284(2002).145 Takhistov, P. and Chang, H.-C., “Complex Stain Morphology”, IEC Res, Special Issue in

HonorofW.R.Scholwalter,41,6256-6269(2002).146 Veretennikov, I., Indeikina, A., Chang, H.-C., Marquez, M., Suib, S. L. and Giraldo, O., “MechanismforHelicalGelFormationfromEvaporationofColloidalSolutions”,Langmuir,18,8792-8798(2002).147 Thamida,S.andChang,H.-C.,“NonlinearElectrokineticEjectionandEntrainmentdueto

Polarization at Nearly Insulated Wedges”, Phys Fluids, 14, 4315-4328(2002). (121citations)

148.Takhistov,P.,Duginova,K.andChang,H.-C.,“ElectrokineticMixingVorticesdueto

Electrolyte Depletion atMicrochannel Junctions”, J. of Colloid and Interfacial Science,263,133-143(2003).

149.Arya,G.,Chang,H.-C.andMaginn,M.J.,“KnudsenDiffusivityofaHardSphereinaRoughSlitPore”,Phys.Rev.Lett,91,026102-1(2003).150. BalakotaiahV.andChang,H.-C.,“Hyperbolichomogenizedmodelsforthermalandsolutal

dispersion”,SIAMJ.AppliedMath.,63(4),1231-1258(2003).151. Arya,G., Chang,H.-C. andMaginn, E. J., “Molecular Simulationsof KnudsenWall Slips---

EffectofWallMorphology”,MolecularSimulation,29,697-709(2003).152. Kopelevich,D.I.andChang,H.-C.“Nonthermaltransportofsmallsorbatesinzeolites:Chaoticdynamicsandlongjumps”,J.Chem.Phys.,119,4573(2003).153. Minerick,A.,Chang,H.-C.,Hoagland,T.M.andOlsen,C.R. “DynamicSynchronizationof

VenousPressure-DrivenCardiacOutputinRainbowTrouts”,Am.JPhysiol.Regul,Integr.AndComp.Physiology,285,889-896(2003)

154. Minerick,A.,Takhistov,P.,Zhou,R.andChang,H.-C.,“Manipulationand

CharacterizationofRedBloodCellswithACFieldsinMicro-Devices”,Electrophoresis,24,3703–3717(2003).(129citations)

155. Kopelevich, D. I. and Chang, H.-C. “Nonequilibrium Transport in and on Condensed

Matters:EffectsofLatticeVibrationandDeterministicChaos”,MolecularSimulation,30, 159-166(2004).156. Yeo,L.,Lastochkin,D.,Wang,S.-C.andChang,H.-C.,“ANewacElectrospray

MechanismbyMaxwell-WagnerPolarizationandCapillaryResonance”,PhysRevLett,92,133902-133904(2004).

157. WangS.C.,Lai,Y.W.,Ben,Y.andChang,H.-C.,“MicrofluidicMixingbydcandacNonlinearElectrokineticVortices”,Ind.AndEng.FundRes.,43,2902-2911(2004).

158. Ben, Y., Demekhin, E. A. and Chang, H.-C., “Superfast Nonlinear Electrokinetics and

Electrophoresis”,JocCollidandInterfaceSci.,276,483-497(2004).159. Lastochkin,D.,Zhou,R.,Wang,P.,Ben,Y.andChang,H.-C.,“ElectrokineticMicropumpand

Micromixer Design Based on AC Faradaic Polarization”, J. of Applied Physics, 96, 1730(2004).(154citations)

160. Wu, J., Ben, Y., Battigelli, D. and Chang, H.-C., “Long-Range AC Electroosmotic Trapping

andDetectionofBioparticles”,Ind.Eng.Chem.Res.,44,2815(2005).(158citations)161. Chen,Z.,Wang,P.andChang,H.-C.,“Anelectro-osmoticmicropumpbasedonmonolithic

silicaformicro-flowanalysesandelectro-sprays”,Anal.BioanalChem,382,817(2005).(64citations)

162. Yeo, L. Y., Gagnon, Z and Chang, H.-C., “AC Electrospray Biomaterials Synthesis”,

Biomaterials,26,6122-6128(2005).(126citations)163.Zhou,R.andChang,H.-C.,“CapillaryPenetrationFailureofBloodSuspensions”,JofColloidandInterfaceScience,287,647-656(2005).164.Chen,Z.,Chang,H.-C.andHobo,T.,“ApplicationofMonolithicSilicaforMicrofluidicAnalysis”,BunsekiKagaku(JapaneseAnal.Chem.),54(7),583-592(2005).165.Yeo,L.andChang,H.-C.,“StaticandSpontaneousElectrowetting”,ModernPhysLett.B,19,549-569(2005).(48citations)166.Lastochkin,D.andChang,H.-C.,“AHigh-FrequencyElectrospraybyGasVolume

Charge”,J.AppliedPhys.,97,123309(2005).167.Gagnon,Z.andChang,H.-C.,“Aligningfastalternatingcurrentelectroosmoticflowfieldsandcharacteristicfrequencieswithdielectrophoretictrapstoachieverapidbacteriadetection”,Electrophoresis,26,3725-3737(2005).168.Wu,J.,Ben,Y.andChang,H.-C.,“Particledetectionbyelectricalimpedancespectroscopywithasymmetric-polarizationacelectroosmotictrapping”,Microlfuid.AndNanofluid.,1,161-167(2005).(124citations)169.Wang,P.,Chen,Z.andChang,H.-C.,“ANewElectro-osmoticPumpHousedinSilicaMonoliths”,SensorsandActuators,113,500(2006).(162citations)170.Yeo,L.andChang,H.-C.,“ElectrowettingFilmsonParallelLineElectrodes”,Phys.RevE,73,011605-1,011605-16(2006).(51citations)171.Zhou,R.,Gordon,J.,Palmer,A.F.andChang,H.-C.,“RoleofEryrhrocyteDeformabilityduringCapillaryWetting”,Biotech.andBioengineering,93,201(2006).172.Zhou,R.,Wang,P.andChang,H.-C.,“Bacteriacapture,concentrationanddetectionbyalternatingcurrentdielectrophoresisandself-assemblyofdispersedsingle-wallcarbonnanotubes”,Electrophoresis,27,1376-1385(2006).(92citations)173,Chang,H.-C.,“Electrokinetics:AViableMicrofluidicPlatformforMiniatureDiagnosticKits”,InvitedReview,CanadianJofChemicalEngineering,84,146(2006)174.Chen,Z.,Hsu,F-C.,Battigelli,D.andChang,H.-C.,“Captureandreleaseofvirusesusingamino-fucntionalizedsilicaparticles”,Anal.Chim.Acta,569,76-82(2006).175.Sengupta,S.,Battigelli,D.andChang,H.-C.,“Amicro-scalemulti-frequencyreactancemeasurementtechniquetodetectbacterialgrowthatlowbio-particleconcentrations”,Lab-on-a-Chip,6,682-692(2006).176.Yeo,L.Y.,Hou,D.,Maheshwari,S.andChang,H.-C.,“Electrohydrodynamicsurfacemicro-vorticesformixingandparticletrapping”,Appl.Phys.Lett.,88,233512(2006).177.Wang,P.,Maheshwari,S.andChang,H-C,“Polyhedraformationandtransientconeejectionofaresonantmicrodropforcedbyanacelectricfield”,PhysRevLett,96,254502(2006).178.Hou,D.andChang,H.-C.,“Electrokineticparticleaggregationpatternsinmicrovorticesduetoparticle-fieldinteraction”,Phys.ofFluids,18,071702(2006).

179.Yeo,L.Y.,Hou,D.,Maheshwari,S.andChang,H.-C.,“Electrohydrodynamicsurfacemicrovorticesformixingandparticletrapping”,AppPhysLett,88,233512(2006).180.Wang,P.,Chen,Z.andChang,H.-C.,“Anintegratedmicropumpandelectrosprayemittersystembasedonporoussilicamonoliths”,Electrophoresis,27,3964(2006).181.Wang,S.-C.,Chen,H.-P.,Lee,C.-Y.,Yu,C.-C.andChang,H.-C.,“ACElectro-osmoticMixingInducedbyNon-ContactExternalElectrodes”,BiosensorsandBioelectronics,22,563(2006).182.Maheshwari,S.andChang,H.-C.,“Anomalousconicalmenisciunderanacfield-departurefromthedcTaylorcone”,App.PhysLett.,89,234103(2006).183.Chen,Z.,Bogess,B.andChang,H.-C.,“Open-tubularCapillaryElectrochromatography-MassSpectrometrywithSheathlessNanoflowElectrosprayIonizationfortheAnalysisofAminoAcidsandPeptides”,JofMassSpectrometry,42,244-253(2007).184.Hou,D.,Maheshwari,D.andChang,H.-C.,“RapidBioparticleConcentrationandDetectionbyCombiningaDischargeDrivenVortexwithSurfaceEnhancedRamanScattering”,Biomicrofluidics,1,014106(2007).185.Zhou,R.,Chang,H.-C.,Ptotempko,V.,Kuno,K.,Singh,P.,Jena,D.andH.Xing,“CdSeNanaowireswithIlluminationEnhancedConductivity:InducedDipoles,DielectrophoreticAssemblyandField-SensitiveAssembly”,JAppPhys,101,073704(2007).(75citations)186.Cheng,I-F.,Chang,H.-C.,Hou,D.andChang,H.-C.,"AnIntegratedDielectrophoreticChipforContinuousBioparticleFiltering,Focusing,TrappingandDetecting",Biomicrofluidics,1,021503(2007).(244citations)187.Basuray,S.andChang,H.-C.,“InducedDipolesandDielectrophoresisofNano-ColloidsinElectrolytes”,PhysRevE.,75,060501-060504(2007).188.Maheshwari,S.andChang,H.-C.,“EffectofBulkChargeandMomentumRelaxationTimeScalesonElectrospraying”,J.App.Phys.,102,034902(2007).189.Wang,S.-C.,Chen,H.-P.andChang,H.-C.,“ACElectro-osmoticPumpingInducedbyNon-ContactExternalElectrodeds”,Biomicrofluidics,1,034106(2007).190.Chang,H.-C.,“NanobeadElectrokinetics:TheEnablingMicrofluidicPlatformforMulti-TargetPathogenDetection”,AIChEJ.,53,2486(2007).191.Gordon,J.E.,Gagnon,Z.andChang,H.-C.,“DielectrophoreticDiscriminationof

BovineRedBloodCellStarvationAgebyBufferSelectionandMembraneCross-linking”,Biomicrofluidics,1,044102(2007).192.Maheshwari,S.,Zhang,L.,Y.ZhuandChang,H.-C.,“Couplingbetween

PrecipitationandContact-lineDynamics:Multi-ringStainsandStick-SlipMotion”,PhysRevLett,100,044503(2008).(101citations)

193. Maheshwari,S.andChang,H.-C.,"Assemblyofmulti-strandednanofiberthreadsthrough

ACelectrospinning",AdvancedMaterials,21,349(2009).194. Gagnon,Z.,Gordon,J.,Sengupta,S.andChang,H.-C.,“BovineRedBloodCellStarvation

Age Discriminatin through a Glutaraldehyde Amplified Dielectrophoretic ApproachwithBufferSelectionandMembraneCross-Linking”,Electrophoresis,29,2272(2008).

195. Zhang,L.;Maheshwari,S.;Chang,H.-C.;Zhu,Y.,"EvaporativeSelf-assemblyfromComplexDNA-ColloidSuspensions",Langmuir,24,3911(2008).196. Wang, S.-C., Wei, H.-H., Chen, H.-P., Tsai, M.-H., Yu, C.-C, and Chang, H.-C., “Dynamic

Superconcentration at Critical Point Double-layer Gates of Conducting NanoporousGranulesduetoAsymmetricTangentialFluxes”Biomicrofluidics,2,014012(2008).

197. Kreft,J.,Chen,Y.-L.andChang,H.-C.,“ConformationandTrappingRateofDNAata ConvergentStagnantFlow”,PhysRevE.,77,030801(R)(2008).198. Hou,D.andChang,H.-C.,"ACField-EnhancedProteinCrystallization",AppliedPhysLett,92,223902(2008)199. Sengupta,S.,Gordon,J.E.andChang,H.-C.,"MicrofluidicDiagnosticSystemsfortheRapidDetectionandQuantificationofPathogens",Chap9of"MicrofluidicsforBiologicalApplications",Editors:W-CTienandE.Finehout,Springer(2008).200. Chang,H.-C.,"RapidandPortableGeneticIdentificationKitsforWorldHealthCareApplications",FeatureArticle,ChineseAmericanChemicalSocietyCommunications,SummerIssue(2008).201. Gagnon, Z. and Chang, H.-C., “Dielectrophoresis of Ionized GasMicro-Bubbles: Double

DipoleReversalduetoDoubleLayerPolarization”,AppPhysLett.,93,224101(2008).202. Gagnon,Z.,Senapati,S.andChang,H.-C.,“DielectrophoreticDetectionandQuantificationofHybridizedDNAMoleculesonNano-GeneticBeads”,Electrophoresis,29,4808(2008).(Fasttrackandcoverfeature).203.Chetwani,N.,Maheshwari,S.andChang,H.-C.,“UniversalConeAngleofacElectrospraysduetonetchargeentrainment”,PhysRevLett.,101,204501(2008).

204.Yossifon,G.andChang,H.-C.,“SelectionofNonequilibriumOverlimitingCurrents:UniversalDepletionLayerFormationDynamicsandVortexInstability”,PhysRevLett.,101,254501(2008).(156citations)205.Gagnon,Z.andChang,H.-C.,“Electrothermalacelectro-osmosis”,AppPhysLett,94,024101(2009).206.Plouraboue,F.andChang,H.-C.,”SymmetryBreakingandElectrostaticAttractionBetweenTwoIdenticalSurfaces”,PhysRevE.,79,041404(2009).207.Chang,H.-C.andYossifon,G.,"UnderstandingElectrokineitcsattheNanoscale--aPerspective",Biomicrofluidics,3,012001(2009).208.Yossifon,G.,Mushenheim,P.,Chang,Y-C.andChang,H.-C.,"NonlinearCurrent-

VoltageCharacteristicsofNanochannels",PhysRevE,79,046305(2009).209.S.Senapati,A.R.Mahon,J.Gordon,C.Nowak,S.Sengupta,T.H.W.Powell,J.Feder,D.M.LodgeandChang,H.-C.,"Rapidon-chipGeneticDetectionMicrofluidicPlatformforRealWorldApplications",Biomicrofluidics,3,022407(2009)210.Basuray,S.,Senapati,S.,Ajian,A.,Mahon,A.R.andChang,H.-C.,“ShearandACFieldEnhancedCarbonNanotubeImpedanceAssayforRapid,SensitiveandMismatch-DiscriminatingDNAHybridization”,ACSNano,3,1823(2009).211.Cheng,X.andChang,H.-C.,“UniversalNanocolloidDepositionPatterns:CanyouseetheharmonicsofaTaylorcone?”,NewJofPhysics,11,075023(2009).212.Yossifon,G.,Chang,Y.-C.andChang,H.-C.,“Rectification,GatingVoltageandInterchannelCommunicationofNanoslotArraysduetoAsymmetricEntranceSpaceChargePolarization”,PhysRevLett,103,154502(2009).213.Cheng,X.,Basuray,S.,Senapati,S.andChang,H.-C.,“IdentificationandSeparationof

DNA-hybridized nanocolloids by Taylor cone harmonics”, Electrophoresis, 30, 3236(2009).

214.Berrouche,Y.,Avenas,Y.,Schaeffer,C.,Chang,H.-C.andWang,P.,“DesignofaPorous ElectroosmoticPumpinPowerElectronicCooling”,IEEETransonIndustry

Applications,45,2073(2009).215.Gagnon,Z.,Mazur,J.andChang,H.-C.,“GlutaraldehydeEnhancedDielectrophoreticYeastCellSeparation”,Biomicrofluidics,3,044108(2009).216.Maheshwari,S.andChang,H.-C."Assemblyofmulti-strandednanofiberthreadsthroughacelectrospinning",AdvMater.,21,349354(2009).

217.Cheng,I-F.,Froude,V.E.,Zhu,Y.,Chang,H.-C.andChang,H.-C.,"AContinuous

High-ThroughputBioparticleSorterBasedon3DTraveling-WaveDielectrophoresis",Lab-on-a-Chip,9,3193(2009).

218.Gagnon,Z.,Mazur,J.andChang,H.-C.,“IntegratedACElectrokineticCellSeparationinaClosed-LoopDevice”,Lab-on-a-Chip,10,718-726(2010).219.Cheng,I.-F.,S.Senapati,X.Cheng,S.Basuray,H-CChangandH.-C.Chang,“ARapidField-UseAssayforMismatchNumberandLocationofHybridizedDNAs”,Lab-on-a-Chip,10,828-831(2010).220.Gagnon,Z.,Senapati,S.,Chang,H-C.,“OptimizedDNAHybridizationDetectiononNanocolloidalParticles”,Electrophoresis,31,666-671(2010).221.Basuray,S.andChang,H.-C.,"DesigningaSensitiveandQuantifiableNanocolloidAssaywithDielectrophoreticCross-OverFrequency",Biomicrofluidics,4,013205(2010).222.Liu,S.-J.,Wei,H.-H.,Hwang,S.-H.andChang,H.-C.,“DynamicParticleTrapping,ReleaseandSortingbyMicrovorticesonaSubstrate”,PhysRevE,82,026308(2010).223.Yossifon,G.,Mushenheim,P.,Chang,Y.-C.andChang,H.-C.,“EliminatingtheLimitingCurrentPhenomenonbyGeometricFieldFocusingintoNanoporesandNanoslots”,PhysRevE,81,046301(2010).224.Yossifon,G.andChang,H.-C.,“ChangingNanoslotIonFluxwithaDynamic

Nanocolloid Ion-selective filter: Secondary Overlimiting Currents due to Nanocolloid-NanoslotInteraction”,PhysRevE,81,066317(2010).

225. Yossifon, G., Mushenheim, P., Chang, Y.-C. and Chang, H.-C., “Controlling NanoslotOverlimiting Current with the Depth of a ConnectingMicrochamber”, EurophysLett, 90,64004(2010).

226.Chetwani,N.,Cassou,C.A.,Go,D.B.andChang,H.-C.,"High-FrequencyACElectrosprayIonizationforMassSpectrometryofBiomolecules",JAmSocMassSpect,21,1852(2010).227.Wang,S.C,Chang,H.-C.andZhu,Y.,“HystereticConformationTransitionofaSingleFlexiblePolyelectrolyteunderResonantacElectricPolarization”,Macromolecules,43,7402(2010).228.Hsiao,P.-Y.,Wei,Y.-F.andChang,H.-C.,"UnfoldingCollapsedPolyelectrolytesin

Alternating-CurrentElectricFields",SoftMatter,7,1207(2011).229.Yeo,L.Y.,Chang,H.-C.,Chan,P.P.Y.andFriend,J.R.,"MicrofluidicDevicesforBioapplications",Small,7,12(2011).(297citations)230.Mahon,A.R.,Barnes,M.A.,Senapati,S.,Feder,J.,Chang,H.-C.andLodge,D.M.,

“MolecularDetectionofInvasiveSpeciesinHeterogeneousMixturesusingaCarbonNanotubePlatform”,PLOSOne,6,17280(2011).

231.Chetwani,N.,Cassou,C.A.,Go,D.B.andChang,H.-C.,“FrequencyDependenceofAlternatingCurrentElectrosprayIonizationMassSpectrometry”,Anal.Chem.,83,3017-3023(2011).232.Ho,J.,Tan,M.K.,Go,D.B.,Friend,J.R.andChang,H.-C.,"APaper-BasedMicrofluidicSurfaeAcousticWaveSampleDeliveryandIonizationSourceforRapidandSensitiveAmbientMassSpectrometry",Anal.Chem.,83,3260-3266(2011)(acceleratedarticle).233.Senapati,S.,Basuray,S.,Slouka,Z.,Cheng,L.-J.andChang,H.-C.,"A Nanomembrane- Based Nucleic Acid Sensing Platform for Portable Diagnostics" , Topics in Current Chemistry, 304, , 153-169(2011). 234. Kuczenski, R. S., Chang, H.-C. and Revzin, A., “Dielectrophorestic Device for Continuous Sorting of Escherichia coli from blood cells”, Biomicrofluidics, 5, 032005 (2011). 235. Cheng, L.-J. and Chang, H.-C., “Microscale pH Actuation by Splitting Water”, Biomicrofluidics, 5, 046502 (2011). 236. Chang, H.-C., Yossifon, G. and Demekhin, E. A. , “Nanoscale Electrokinetics and

Microvortices: How Microhydrodynamics Affects Nanofluidic Ion Flux”, Annual Rev of Fluid Mech, 44, 401-426 (2012).

237. Revzin, A., Maverakis, E. and Chang, H.-C., “Biosensors for Immune Cell Analysis—A Perspective”, Biomicrofluidics, 6, 021301 (2012). 238. Wang, Y., Tan, M. K., Go, D. and Chang, H.-C., “Electrospray Cone-Jet Breakup and Droplet Production for Electrolyte Solutions”, Europhys Lett, 99, 64003 (2012). 239. Taller, D., Go, D. B. and Chang, H.-C., “Self-Similar Micron-size and Nanosize Drops of Liquid Generated by Surface Acoustic Waves”, Phys Rev Lett, 109, 224301 (2012). 240. Chang, H.-C., Demekhin, E. A. and Shelistov, V. S., "Competition Between Dukhin's and Rubinstein's Electrokinetic Modes", Phys Rev E, 86, 046319(2012). 241. Conroy, D. T., Craster, R. V., Matar, O. K., Cheng, L.-J. and Chang, H.-C., “Non- Equilibrium Hysteresis and Wien Effect Water Dissociation at a Bipolar Membrane”, Phys

Rev E, 86, 056104 (2012). 242. Yan, Y., Wang, L., Xue, J., and Chang, H.-C., “Ion Current Rectification in Conic Nanopores: Nonequilibrium Ion Transport Biased by Ion Selectivity and Spatial Asymmetry”, J Chem. Phys., 138, 044706 (2013). 243. Yan, Y., Qian, S., Wang, C., Xue, J. and Chang, H.-C., “Energy Conversion Efficiency of

Nanofluidic Batteries : Hydrodynamic Slip and Access Resistance”, J Phy Chem C, 117, 8050 (2013).

244. Wang, Y., Cheng, X. and Chang, H.-C., “Celebrating Singularities: Mathematics and Chemical Engineering”, AIChE J, 59, 1830 (2013). 245. Wang, Y. , Plouraboue, F. and Chang, H.-C., "Broadband Converging Plasmon Resonance at a Conic Nanotip", Optics Express, 21, 6609(2013). 246. Taller,D.,Go,D.N.andChang,H.-C.,"ModulatedExponentialFilmsGeneratedbySurfaceAcousticWavesandTheirRoleinLiquidWickingandAerosolizationataPinnedDrop",PhysicalRevE,87,053004-6(2013).247.Slouka,Z.,Senapati,S.,Yan,Y.andChang,H.-C.,“ChargeInversion,WaterSplitting,andVortexSuppressionDuetoDNASorptiononIon-SelectiveMembranesandTheirIon-CurrentSignatures”,Langmuir,29,8275-83(2013).248.Liu,S.,Yan,Y.,Wang,Y.,Senapati,S.andChang,H.-C.,“PlasmonicHotspotsofDynamicallyAssembledNanoparticlesinNanocapillaries:TowardsamiRNAProfilingPlatform”,Biomicrofluidics,7,061102(2013).249.Hsiao-PingChen,Chia-ChunTsai,Hung-MengLee,Shau-ChunWangandHsueh-ChiaChang,“SelectiveDynamicConcentrationofPeptidesatPolesofCation-SelectiveNanoporousGranules”,Biomicrofluidics,7,044110(2013).

250.Cheng,L.-J.andChang,H.-C.,“SwitchablepHActuatorsand3DIntegratedSaltBridgesasNew Strategies for Reconfigurable Microfluidic Free-Flow Electrophoretic Separation”,LabChip,14,979(2014).

251.Wang,Y.,T.-C.Chang,Stoddart,P.R.andChang,H.-C.,"Diffraction-LimitedUltrasensitiveMolecularNano-ArrayswithSingularNanoconeScattering",Biomicrofluidics,8,021101(2014)252.Senapati,S.,Slouka,S.,Shah,S.S.,Behura,S.K.,Shi,Z.,Stack,S.,Severson,D.W.andChang,H.-C.,“AnIon-ExchangeNanomembraneSensorforDetectionofNucleicAcidsUsingaSurfaceChargeInversionPhenomenon”,BiosensorsandBioelectronics,60,92-

100(2014).253.Slouka,Z.,Senapati,S.andChang,H.-C.,“MicrofluidicSystemswithIon-SelectiveMembranes”,AnnualReviewofAnalyticalChemistry,7,317-335(2014).

254. O’Neil, P. F., Ben Azouz, A., Vazquez, M., Liu, J., Marczak, S., Slouka, Z., Chang, H.-C., Diamond, D. and Brabazon, D. “Advances in Three-Dimensional Rapid Prototyping of Microfluidic Devices for Biological Applications”, Biomicrofluidics , 8, 052112 (2014).

255.Rajesh,S.,Yan,Y.,Chang,H.-C.,Gao,H.andPhillip,W.A.,“MixedMosaicMembranesPreparedbyLayer-by-LayerAssembly”,ACSNano,8(12),12338-12445(2014).256.Taller,D.,RichardsK.,Slouka,S.,Senapati,S.,Hill,R.,Go,D.B.andChang,H.-C.,”On-ChipSurfaceAcousticWaveLysisandion-exchangemembranedetectionofexosomalRNAforpancreaticcancerstudyanddiagnosis”,LabChip,15,1656-1666(2015)(CoverArticle)257.Sun,G.,Slouka,Z.andChang,H.-C.,“FluidicBasedIonMemristorsandIonLatches”,Small,11,5206-5213(2015).258.Slouka,Z.,Senapati,S.,Shah,S.,Lawler,R.,Shi,Z.,Stack,S.andChang,H.-C.,“Integrated,DCVoltage-DrivenNucleicAcidDiagnosticPlatformforRealSampleAnalysis:DetectionofOralCancer”,Talanta,145,35-42(2015).259. Yan, Y., Schiffbauer, J. , Yossifon, G. and Chang, H.-C., “Universal Low-Frequency

AsymptotesofDynamicNanoporeRectification:An IonicNanofluidic Inductor”, J.ChemPhys,143,224705(2015).

260. Rosentsvit, L., Wang, W., Schiffbauer, J., Chang, H.-C. and Yossifon, G., “Ion Current

Rectification inFunnel-ShapedNanoChannels:Hysteresisand InversionEffects”, J.Chem.Phys,143,224706(2015).

261.Sun,G.,Senapati,S.andChang,H.-C.,“High-fluxionicdiodes,ionictransistorsandionicamplifiersbasedonexternalionconcentrationpolarizationbyanionexchangemembrane:anewscalableioniccircuitplatform”,LabChip,16,1171–1177(2016).(CoverArticle).262.Egatz-Gomez,A.,Wang,C.,Klacsmann,F.,Pan,Z.,Marczak,S.,Wang,Y.,Sun,G.,Senapati,S.andChang,H.-C.,“FutureMicrofluidicandNanofluidicPlatformsforNucleicAcidBiopsy

inPrecisionMedicine”,Biomicrofluidics,10,032902(2016).263.Marczak,S.,Senapati,S.,Slouka,Z.andChang,H.-C.,“InducedNanoparticleAggregationforShortNucleicAcidQuantificationbyDepletionIsotachophoresis”,BiosensorsandBioelectronics,86,840-848(2016).

264.Pan,Z.,Wang,C.,Li,M.andChang,H.-C.,“UniversalScalingofRobustThermalHotspotandIonicCurrentEnhancementbyFocusedOhmicHeatinginaConicNanopore,PhysicalReviewLetters,117,134301(2016).265.Shah,S.S.,Senapati,S.,Klacsmann,F.,Miller,D.L.,Johnson,J.J.,Chang,H.-C.,Stack,M.S.,“CurrentTechnologiesandRecentDevelopmentinScreeingofHPV-AssociatedCervicalandOropharyngealCancers”,Cancers,8,85(2016)266.Li,D.,Wang,C.,Sun,G.,Senapati,S.andChang,H.-C.,“AShear-EnhancedCNT-AssemblyNanosensorPlatformforUltra-SensitiveandSelectiveProteinSensing”,BiosensorsandBioelectronics,97,143(2017).267.Sun,G.,Pan,Z.,Senapati,S.andChang,H.-C.,“Concentration-GradientStabilizationwithSegregatedCounter-IonandCo-IonPaths:AQuasi-StationaryDepletionFrontforRobustMolecularIsolationorConcentration”,PhysicalRevApp,7,064024(2017).268.Go,D.,Atashbar,M.Z.,Ramshani,Z.andChang,H.-C.,“SurfaceAcousticWaveDevicesforChemicalSensingandMicrofluidics:aReviewandPerspective”,AnalyticalMethods,9,412(2017).269.Marczak,S.,Smith,E.,Senapati,S.andChang,H.-C.“Selectivityenhancementsingel-basedDNA-nanoparticleassaysbymembrane-inducedisotachophoresis:thermodynamicsversuskinetics”.Electrophoresis,38:2592(2017).270.Sensales,S.,Peng,Z.andChang,H.-C.,“KinetictheoryforDNAmeltingwithvibrationentropy”,JChemPhys,147,135101(2017).271.Marczak,S.,Richards,K.,Ramshani,Z.,Smith,E.,Senapati,S.,Go,D.B.andChang,H.-C.,“Simulateneousisolationandpreconcentrationofexosomesbyionconcentrationpolarization”,Electrophoresis,39,2029(2018).272.Pan,Z.,Men,Y.,Senapati,S.andChang,H.-C.,“ImmersedACElectrospray(iACE)formonodispersedaqueousdropletgeneration”,Biomicrofluidics,12,044113(2018)(Editor’sPick).273.Sensale,S.,Peng,Z.andChang,H.-C.,“AccelerationofDNAmeltingkineticsusingalternatingelectricfields”,JofChemPhys,149,085102(2018).

Invited Seminars (Over 150)

"A Singular Perturbation Analysis of the Dynamics of Two-Species HeterogeneousCatalyticReactions,"UniversityofCaliforniaatDavis,1980."Quasi-Steady-State Analysis of Heterogeneous Catalytic Systems," University ofHouston,1980."Multi-Scale Analysis of Global Dynamics in Heterogeneous Catalytic Systems,"UniversityofSouthernCalifornia,1982."TheNonlinearEffectsofStabilizinganUnstableReactorbyLinearFeedbackControl,"NotreDame,1983."NonlinearDynamicBehaviorinChemicalSystems,"TexasA&M,1983."HighReynoldsNumberFlowThroughCubicArraysofSpheres,"UniversityofCalifornia,SanDiego,1983."TransportinperiodicArraysofSpheresandCylinders,"UniversityofHouston,1984. "BifurcationsofaFallingLiquidFilm,"UniversityofWisconsin,1984,"Evolution on Nonlinear Waves on Falling Films - A Normal Analysis," University ofMassachusetts,1985."EffectiveConductivityandDiffusivityinTwo-PhaseMedia,"MichiganStateUniversity,1985."NonlinearInterfacialInstability,"Schlumberger-Doll,Ridgefield,Connecticut,1985."Modelling of Flow in Permeable Media," Gordon Research Conference, NewHampshire,1986. "AGalerkin/Spectral Analysis of FlowTransition in SeveralModel Systems," PrincetonUniversity,1986."NonlinearDynamicsofSystemsUnderPIDControl,"UniversityofTexas,Austin,1986."DesignofPIDControllers forNonlinearSystems-AModel IndependentMethodBasedonBifurcationTheory,"Caltech,1986.

"FlowTransitioninPorousMedia,"UniversityofNotreDame,1987."PIDControlofNonlinearSystems,"UniversityofPennsylvania,1987."Tuning of PI Controllers for Unknown Systems," East China Institute of ChemicalTechnology,1987."NonlinearWavesonFallingFilms,"EastChinaInstituteofChemicalTechnology,1987."FlowTransitioninPorousMedia,"AcademiaSinica,1988."BubbleTransportinCapillaries",ColburnLectureship,UniversityofDelaware,1988.

"GeneralDynamicPropertiesofNonlinearSystemsunderPIControl",NationalTaiwanUniversity,1988.

"BubbleTransportinCapillaries",NationalTaiwanUniversity,1988. "Nonlinear Dynamics of Systems Under Feedback Control", Illinois Institute ofTechnology,1989."TheMarangoniEffectontheTransportofBubbles inCapillaries",EngineeringScienceandAppliedMathDept.,NorthwesternUniversity,1990. "Apparent Viscosity of Bubble Trains in Capillaries", Rheology Seminar, University ofWisconsin,1990."AGeneralizedSidebandStabilityTheory",AerospaceEngineeringandMechanicsDept.,UniversityofMinnesota,1990."Selection of Periodic Patterns in Unbounded Domains", Institute of TheoreticalChemistry,UniversityofTubingen,Germany,1990."SelectionofPeriodicPatternsinUnboundedDomains",InstituteofPaperScienceandTechnology,GeorgiaInstituteofTechnology,1990."DisplacementofLiquidbyAirBubbles inCapillaries - theMarangoniEffect",ClarksonUniversity,1990."Displacement of Liquids by Air Bubbles in Capillaries - the Marangoni Effect", MIT,1991."Bifurcation of a Torus in a Delayed Feedback System", Institute of Control Science,USSRAcademyofScience,Moscow,1991.

"HeatTransferEnhancementbyChaoticMixing",ArgonneNationalLaboratory,1991."TransitionandPatternFormationinMulti-PhaseChannelFlow,"ChemicalEngineeringDept.,CornellUniversity,1991."InterfacialPatternsandInvariantManifolds",AppliedMath.Group,CornellUniversity,1991."SpatialPatterns inTwo-PhaseFlow",ChemicalEngineeringDepartment,UniversityofIowa,1992."PatternFormationinMulti-PhaseFlow",MathematicsDepartment,VirginiaTech,1992."InterfacialWaveDynamicsonThinFilms",JamesandCatherinePatternSeminar,UniversityofColorado,Boulder,1992."InterfacialWaveDynamics",WestVirginiaUniversity,1992."Surface-TensionDrivenFlow",WestVirginiaUniversity,1992.

"Spatio-TemporalChaosandControlonaCatalyticWafer",NationalTaiwanInstituteofTechnology,Taipei,December22,1992.

"HeatTransferEnhancementbyChaoticMixing",NationalTaiwanUniversity,Taipei,December22,1992."Heat Transfer Enhancement by Chaotic Mixing", National Tsing Hua University, Hsinchu,December23,1992."InterfacialChaos",TunghaiUniversity,Taichung,December23,1992."Instabilities in Free Convection Near a Heated Plane", Chemical Engineering Department,NationalChengKungUniversity,Tainan,December26,1992."Displacement of Liquid by Air Bubbles in Capillaries", Chemical Engineering Department,NationalChengKungUniversity,Tainan,December28,1992."Heat-Transfer Enhancement by Chaotic Mixing", Aeronautical Department, National ChengKungUniversity,Tainan,December29,1992."Spatio-TemporalChaosandControlonaCatalyticWafer",ChemicalEngineeringDepartment,NationalChengKungUniversity,Tainan,December30,1992.

"Interfacial Chaos", Mechanical Engineering Department, National Cheng Kung University,Tainan,December31,1992."WaveEvolutiononaFallingFilm,"DepartmentofAppliedMathematicsandTheoreticalPhysics,CambridgeUniversity,October22,1993."WaveEvolutionon a Falling Film," Prague Instituteof Chemical Technology,October26,1993."Wave Evolution on a Falling Film", Department of Mathematics, University ofBirmingham,November19,1993."Self-similar Solutions in Interfacial Dynamics", Chemical Engineering Department,Carnegie-Mellon,January25,1994."Interaction Dynamics of Solitary Waves on a Falling Film", Complex Fluid SeminarSeries,PrincetonUniversity,Sept.26,1994."WavesonaFallingFilm",LevichInstituteofHydrodynamics,CityCollegeofNewYork,Sept.27,1994."WaveDynamicsonaFallingFilm",UniversityofMissouri-Rolla,March29,1995."Wave Evolution on a Falling Film", Spatially Extended Conference on ComplexDynamicsinSpatiallyExtendedSystems,NielsBohrInstitute,Denmark,Sept.26,1995."WaveDynamicsonaFallingFilm",UniversityofWisconsin,January24,1996

"Self-SimilarityinInterfacialDynamics",PhysicsDepartment,UniversityofChicago,April15,1996."FallingFilmDynamics,",MathematicsDepartment,UniversityofAlabama,May1,1996."A Description of Film Wave Dynamics by Coherent Structure Theory", AppliedMathematicsDepartment,NorthwesternUniversity,May12,1997."Pattern Formation During Electropolishing", Fritz-Haber-Institut der Marx-Planck-Gesellscaft,Berlin,July21,1997."Drop Formation in Viscoelastic Jets", Department of Mathematical Sciences,Indiana/PurdueUniversity,Indianapolis,October15,1997."Drop Formation and Pinchoff in Viscoelastic Jets", Mech. Eng. Dept., Arizona StateUniversity,November21,1997.

"WaveDynamicsonThinFilms","PatternFormationinCorrosionandElectropolishing"and"BreakupofViscoelasticJets",MathematicsandEngineeringDepartments,InstituteofTechnologyatBundung,Indonesia,January7-9,1998."WaveDynamicsonaFallingFilm",Mech.Eng.Dept.,MIT,February27,1998."Modulation Instability of Kinematic InterfacialWaves",Mech. Eng.Dept.,UCLA,May14,1998."WaveDynamicsonaFalling,Film",Chem.Eng.Dept.,UCLA,May15,1998."HomogenizationandScalingTheoriesforMolecularTransportinZeolites",Chem.Eng.Dept.,UniversityofNaples,June16,1998."Arnold Diffusion in Zeolite Crystals", Aerospace and Mechanical Engineering Dept.,UniversityofNotreDame,Aug.31,1999."Nanoscale Pattern Formation During Electrode Dissolution", Chemical EngineeringDept.,UniversityofFlorida,Oct.18,1999."Nanoscale Pattern Formation During Electrode Dissolution", Chemical EngineeringDept.,UniversityofHouston,November19,1999."Fast-Igniting Catalytic Converters", Chemical EngineeringDept., Iowa State,March 2,2000."NanoscalePatternFormation",Fritz-Haber-InstitutderMarx-Planck-Gesellscaft,Berlin,June16,2000."Fast-Igniting Catalytic Converters", Department of Mathematics, University ofMinnesota, Minneapolis, September 7, 2000; Nonlinear Dynamics Seminar Series,AppliedMathProgram,PrincetonUniversity,October23,2000."Fast-IgnitingCatalyticConverters",DepartmentofMathematics,NewJerseyInstituteofTechnology,Newark,November3,2000.“Fast-Igniting Catalytic Converters”, Mathematics Department,Chinese NormalUniversity,Taipei,Taiwan,December27,2000.“MicrodevicesandNanoporousMaterials”,CollegeofEngineering,YuanZeUniversity,Taiwan,December28,2000.

“Microfluidics”,ChemicalEngineering,NationalTaiwanUniversity,Dec18,ChungChengUniversity,Dec20,ChengKungUniversity,Dec22,ChanganHospitalandUniversity,Dec24,Taiwan,2001.“Microfluidics”, Chemical Engineering, Natioal Seoul University, January 8, KAIST,January10,KIST,January11,Korea,2002.“WaveDynamics on Thin Films”, Department ofMathematics, Penn State, February,2002.“Electrokinetic Microfluidics”, Stanley Corrsin Hydrodynamics Lecture, Johns HopkinsUniversity,March7,2002.“ElectrokineticMicrofluidics”,UniversityofWisconsin,April9,2002.“Nonlinear Electrokinetic Phenomena and theirMicrofluidicApplications”,MechanicalEngineeringDept,LouisianaStateUniversity,September18,2002.“Bioparticle Separation and Detection with Micro-Devices”, Academia Sinica, Taipei,Taiwan,December26,2002.“Miniature Medical Diagnostic Kits”, National Nano-Device Laboratory, Hsin-Chu,Taiwan,December27,2002.“ApplicationofElectrokineticstoMicro-FluidicDevices”,Carnegie-Mellon,Feb18,2003.“EngineeringDoubleLayerstoControlElectro-DissolutionProcesses”,AshlandResearchLaboratory,Columbus,Ohio,April16,2003.“Nano-scale Dissolution Patterns During Electropolishing and Anodization”, ArgonneNationalLaboratory,MaterialScienceDivision,May1,2003.“Nonlinear Electrokinetics and Microfluidic Devices”, Workshop on Complex Fluids,ArgonneNationalLaboratory,July28to31,2003.

“ApplicationofElectrokineticsinMicro-fluidicDevices”,UniversityofMinnesota,Oct7,2003.

“ApplicationofElectrokineticsinMicro-fluidicDevices”,MichiganTech,Oct23,2003.“Application of Electrokinetics in Micro-fluidic Devices”, Tsinghua University, Dec 18,2003.

“ApplicationofElectrokineticsinMicro-fluidicDevices”,NationalTaiwanUniversity,Dec24,2003.“Application of Electrokinetics in Micro-fluidic Devices”, Center of Bioengineering and Mechanical Engineering Department, University of Missouri, April 6, 2004.

“Non-equilibriumElectrokinetics”,DepartmentofAerospaceandMechanicalEngineering,UniversityofNotreDame,Sept28,2004.

“ACElectrokineticDevices”,DepartmentofBioengineering,RiceUniversity, December11,2004.

“MicrofludicDesigns forMiniatureMedicalDiagnosticKits’,KeynoteLecture, (Taiwan)BiomedicalEngineeringSocietyAnnualSymposium,Tainan,Taiwan,December18,2004.

“ElectrorkineticMicrodevices”,DepartmentofChemicalEngineering,Cheng-Kung

University,Tainan,Taiwan,Dec20,2004. “MiniatureBloodDiagnosticKits”,DepartmentofBiomedicalEngineering,Cheng-Kung University,Tainan,Taiwan,Dec21,2004.

“Microfludic Designs for Miniature Medical Diagnostic Kits’, College of EngineeringHonorLecture,Chong-ChengUniversity,Chia-Yi,Taiwan,Dec24,2004.“Microfluidic Technology fro Rapid Diagnostic Kits”, Bioengineering Department, RiceUniversity,January31,2005.“RapidDiagnosticKitsforCancerDetection”,Han-MoKooMemorialSeminar,VanAndelResearchIntitute,GrandRapids,Feb9,2005.“MicrofluidicTechnologyfroRapidDiagnosticKits”.ChemicalEngineeringDepartment,UniversityofAlberta,March17,2005.“Microfluidic Technology for Rapid Diagnostic Kits”, Invited Speakers, BiosensorSymposium,Indianapolis,April6,2005.“MicrofluidicTechnologyforRapidDiagnosticKits”,ChemicalEngineeringDepart,ment,UniversityofHouston,April15,2005.“Microfluidic Technology for Rapid Diagnostic Kits”, Chemical Engineering Depart,ment, Tsinghua University, Beijing, May 12, 2005.

“Thin Films of SoftMatter”, The Bianchi Session, International Center forMechanicalSciences,Udine,Italy,July18to22,2005.“Designing DC and AC Electrokineitc Devices forMiniature Diagnostic Kits”, ChemicalEngineering,Univ.ofMass,Amherst,Oct6,2005.“ManipulatingNanobeadsandNanorodswithMicro-ElectrodestoCapture,DetectandIdentify Virus/Bacteria”, International Symposium on Nano Bioengineering, Chung-Li.Taiwan,Dec15-16,2005.“AC Electrokinetics due to Double Layer Charging”, Exxon-Mobil and Levich Institute,October23and24,2006.“DirectedAssemblyofColloidsbyACElectrokinetics”,NSF-NSCUS/TaiwanWorkshoponSoftMaterials,Taipei,Jan4-6,2007.“Dielectrophoresis: Double-Layer Effects”, Invited Speaker,Material Research Society,SanFrancisco,April13,2007.“Dielectrophoresis of Nano-Colloids---a New Microfluidic Platform for BiomedicalDiagnostic Kits”, Monash University, University of Queensalnd and MelbourneUniversity,Australia,May21-29,2007.“Dielectrophoresis of Nano-Colloids”, Sandia National Lab., September 24;BioengineeringDepartment,UCDavis,September25,2007.“DielectrophoresisofNano-Colloids”,ChemicalEngineering,Caltech,Oct,18,2007.“Dielectrophoresis of Nano-Colloids”, HKUST, Hong Kong, January, 2008; AcademiaSinica,National TaiwanUniversity, Cheng KungUniversity, Central University, Taiwan,March,2009.“DielectrophoresisofNano-Colloids”,ChemicalEngineering,Princeton,April23,2008.“ACElectrospray”,KavliInstituteofPhysics,Beijing,June,2008.“UnderstandingEletrokineticsattheNanoscale”,MechanicalEngineeringdepartment,UniversityofHouston,February2009.“UnderstandingElectrokineticsattheNanoscale”,SEAS,UniversityofPennsylvania,April,2009.“UnderstandingElectrokineticsattheNanoscale”,ChineseAcademyofScience,AppliedScienceInsitute,Shanghai,July2009.

KeynoteLecturer,ACSColloidandInterfacialScienceSymposium,ColumbiaUniversity,

June2009. Keynote Lecture, ASME Mini/Micro/NanoChannels Conference, Pohang, Korea, June

2009. KeynoteLecture,Asian-PacificLabChipConference,Shanghai,October2009. InvitedSpeaker,WorkshoponElectrokinetics,IMA,UniversityofMinnesota,Dec2009.Keynote Lecturer, Second ASME Micro/Nanoscale Heat/Mass Transfer International

Conference,JiaotungUniversity,Shanghai,December2009. InvitedSpeaker,ElectrokineticsConference,Banff,February2010. “RapidLabel-FreeMolecularDetectionbyElectrokinetics”,EPA,Cincinnati,April2010. “Nanofluidics”, Academia Sinica, Taiwan, June, 2010; National Tsing-Hua University,

June,2010.NationalChengKungUniversity,June,2010. “VorticesandInstabilitiesattheMicro/Nanoscale”,PlenaryLecture,WavePhenomena

IV,Banff,Canada,June2010. “Polaritons at Geometric Singularities”, Invited Speaker, Phoresis Workshop, Pohang,

Korea,August2010. “NanoporousMembraneSensorsforPortableNucleicAcidDetection”,PlenarySpeaker,

Chinese-Japan-KoreaAnalyticalChemistryConference,Wuhan,October2010. “Polaritons at Geometric Singularities”, Plenary Speaker, Electrokinetics Workshop,

Haifa,Israel,December2010. “A new Nucleic Acid Detection Platform based on NanoporousMembranes”, Plenary

Speaker,AMN-APLOC,Singapore,January,2011. “A Nanofluidic Platform for Cancer Biomarker Detection”, Nano-Air ForceWorkshop,

Seattle,March,2011. “Micro and Nanofluidics for Mass Spectrometry and Biosensing”, Mechanical

EngineeringDepartment,UniversityofLouisville,March,2011. “PolaritonsandGeometricSingularities”,NanofluidicsColloquim,Physicsdepartment, UniversitaitTwente,June2011.

“ElectrokineticBiochips”,ChemicalEngineering,ImperialCollege,June2011. “Electrokinetic Biosensors”,Mechanical Engineering, University College, London, June

2011. “Non-Equilibrium Nanofluidics: Rectification, Overlimiting Current and MicroVortex

Instability”,Engineering,BrownUniversity,September2011. “Rectification, Hysteresis and Oscillations in Nanofluidics”, Invited Speaker,

Electrokinetics Symposium, APS-DFD Annual Meeting, Baltimore, November2011.

“Microvortex Turbulence Driven by Non-Equilibrium Ion Flux through Ion-Selective

Media”,FluidSeminar,StanfordUniversity,January,2012. “Nanoporous Membrane Sensor”, Plenary Lecture, Advances in Microfluidics and

Nanofluidics,Dalian,China,May,2012. “Low-CostMembraneSensorsforPortableDiagnostics”,MarineEnvironmentalSensing

Center,DublinCityUniversity,Aug30,2012. “AnomalousPhenomenaatGeometricSingularities”,PhysicsDepartment,Universityof

Missouri,September17,2012 “Ion Rectifiers, Capacitors and Inductors”, Mechanical Science and Engineering,

UniversityofIllinois,Urbana,September18,2012. “ElectrokineticTechnologiesforPortableDiagnosticDevices”,ChemicalEngineering. OhioStateUniversity,November15,2012. “Next-Generation Molecular Diagnostics”, Bionics Innovation Center, Pazmany P.

CatholicUniversity,Budapest,September17,2013. “Field-UseNucleicAcidSensors”,Bioengineering,UniversityofTexas,ElPaso,October

11,2013. “Next-GenerationofDiagnosticDevices”,BionicsCenter,Budapest,Hungary,Sept17,2013. “NextGenerationMolecularDiagnostics”, Suzhou InstituteofBiomedicalEngingeering

andTechnology,Oct23,2013.

“Next Generation Molecular Diagnostics”, Plenary Talk, International Conference ofAppliedScience,AcademiaSinica,Taiwan,Oct25,2013.

“Nanoporous Membrane Biosensor”, Mechanical Engineering Department, Clemson

University,Nov21,2013. “Nanoparticle Assembly for Plasmonic Biosensing”, Foundations of Nano Science,

Snowbird,Utah. “MembraneMicrofluidics”,AdvancesinMicrofluidicsandNanofluidics,AcademiaSinica,

Taipei,May24-26,2014. “MembraneMicrofluidics”,Dielectrophoresis2014,InstituteofPhysics,London,July14-

16,2014. “Ultra-SensitiveBiosensingwithNanoporeIon-CurrentsandNanoparticlePlasmonics”KeynoteSpeaker,China-GermanOpticalMedicalDevicesConference,Suzhou,Sept18-19,2014. “Next-Generation Point-of-Care Diagnostics”, Workshop on Bionics, Bionics Center,

PazamanyPeterCatholicUniversityBudapest,Oct21-23,2014. “Next-Generation Point-of-Care Diagnostics”, Keynote Lecture, Taiwan Institute of

ChemicalEngineersMeeting,Taoyuan,Taiwan,Dec13,2014. “Next-Generation Point-of-Care Diagnostics”, Applied Sciences Division, Academia

Sinica,Taiwan,Feb6,2015. “Next-GenerationPoint-of-CareDiagnostics”,UniversityofChile,Santiago,Chile,March

9,2015.CatholicUniversity,Santiago,Chile,March11,2015. “Next-GenerationPoint-of-CareDiagnostics”,PlenarySpeaker,7thWACBEWorldCongressonBioengineering,Singapore,July6,2015. “PortableNucleicAcidSensors”,BioselectMicrofluidicCongress,SanDiego,Sept2015. “NucleicAcidAssay:HowtobeatThermodynamicEquilibrium”,BioengineeringDepartment,UniversityofCalifornia,SanDiego,September30,2015. “IntegratedMembraneSensor”,PlenarySpeaker,AnnualMeetingofAmericanElectrophoresisSociety,SaltLakeCity,November2015. “Ionic Circuits”, Electrical Engineering Department, University of Utah, November 5,

2015.

“Next-GenerationPoint-of-CareDiagnostics”,ChemicalEngineeringDepartment,NationalUniversityofSingapore,January2016;IMRE,ASTAR,Singapore,January2016. “MembraneMicrofluidicsformiRNAProfiling”,MechanicalEngineering,UniversityofPittsburg,March2016. “ABillion-DropletDigitalPCRPlatform”,Keynotelecture,MicrofluidicsCongress,SanDiego,September2016. “IonicCircuitsforMolecularAnalysis”,Keynotelecture,BionicsCenterPhDCongress,Budapest,Hungary,November2016. “IonicCircuitsforMolecularDiagnostics”,PhysicsofMicrofluidics,Israel,January2017. "NanotechnologyforExosomeandmiRNAIsolation/Quantification,"NotreDameHarperCancerInstitute-USCNorrisCancerCenterretreat,UniversityofSouthernCalifornia,February9,2017. “BiochipsforShortNucleicAcidQuantificationBasedonNonlinearIonicCircuitrieswithPerm-SelectiveMembranes”,MechanicalEngineering,UniversityofAlberta,April2017. "BiochipsforShortNucleicAcidQuantificationBasedonIon-SelectiveNanoporousMembranesandNanopores,"MaterialsWeek,OhioStateUniversity,May,2017.

"NanoporeTranslocationandUnbiasedmiRNAProfiling,"PlenaryTalk,AMN-ISMN-APCBM-ANZNMFconference,Tasmania,AustraliaJune29,2017“NanoporeQuantificationofmiRNA”,PlenaryTalk,MicrofluidicsCongress,SanDiego,October2,2017.

“Towardsquantificationoflarge-librarybiomarkersforpersonalizedmedicine”,PlenaryTalk,AdvancesinPharmaceuticalAnalysis,Wuhan,November18,2017.“NanoporemiRNAprofilingTechnology”,PlenaryTalk,MicrofluidicsWorkshop,ChineseAcademyofScience,InstituteofModernPhysics,Lanzhou,June13,2018.“Biosensorsbasedonnonlinearioniccircuits,Distinguishedlecture,DepartmentofMechanicalEngineering,BostonUniversity,September14,2018.

Funded Research (Over $25 Million) NSF,DOE,DOD,NASA,NIH,USDA,IBM,ExxonMobil,FarEastern,Schlumberger,NavalMedicalLab,AirForceOfficeofResearch,ArmyCorpofEngineering,DTRA,ACS-PRF,GreatLakesConservationAgency,WelchFoundation,WalterCancerFoundation,GasResearchInstitute,TAPPI,BayerDiagnostics,US-IsraelBSF."PerturbationAnalysisofHeterogeneousCatalyticDynamics,"NSF,1981-1984,$50,000. "AnalysisofTransientBehaviorinChemicalEngineering,"ACS-PRF,1981-1983,$10,000. "Transport inPorousMedia - SteadyandDynamicBehaviors in Inertial andTurbulent

Regions,"ACS-PRF,1984-1986,$33,000. "WashingandPluggingMechanisminFormationDamage,"SchlumbergerWell Service,1985-1986,$20,000. "ApplicationofNonlinearTechniquestoControlandFluidDynamics-PYIAward,"NSF,

1985-1990,$500,000.(REUSupplement:$15,000) "EnhancedOilRecoveryConsortium,"1985-1987,$95,000/yearfromindustrialsponsors,

$50,000/yearfromstatefunds.PI:H.Deans(WithE.Claridge). "DynamicModelingofCOOxidationonPlatinum,"TheRobertA.Welch Foundation,1986-1987,$60,000. "HighReynoldsNumberFlowinPorousMedia,"ACS-PRF,1986-1988,$35,000. "Dielectric Breakdown Due to Electrothermal Instability," Jesse M. Jones Faculty

ResearchFund,1988-1989,$10,000. "Stability of Core-Annular Flow in Lubricated Transport of Oil", ACS-PRF, 1988-1990,

$40,000.(WithM.J.McCready.) "EnhancementofHeatTransferbyChaoticMixing",GasResearchInstitute,1990-1993,

$300,000(WithM.Sen). "NonlinearDynamicsandControlofComplexPatterns",NSF,1991-1994,$200,000. "HydrodynamicInstabilityofForming",TAPPI,1992,$40,000.

"WaveDynamics on Falling Films and Its Effects onHeat/Mass Transfer", DOE, 1992-1995,$185,000.

"Thermal Front Propagation of Fast Igniting Catalytic Converters", 1992-1995, NSF,

$250,000(WithE.E.Wolf).(REUSupplement:$15,000) "Study of disturbances in fluid-fluid flows in open and closed systems", NASA, 1992-

1995,$300,000(withM.J.McCreadyandD.T.Leighton). "Fundamental Processes of Atomization in Fluid-Fluid Flows", NASA, 1996-2000,

$520,000,(withM.J.McCreadyandD.T.Leighton). "NonlinearDynamicsandControl,"NSF,1996-1999,$170,000.(REUSupplement:$20,000) "WhenareHexagonsPreferred,"FacultyResearchProgram,1997,$7,500. "ElectrochemicalSelf-Organization,"NSF,1997-2000,$220,000,(withA.E.Miller). "Molecular Design of Lubricants", Mobil Foundation, 1998-2000, $30,000 (with E. J.

Maginn). "Wave-Enhanced Heat and Mass Transfer", NSF, 1998-2000, $160,000 (with M. J.

McCreadyandK.T.Yang).(REUSupplement:$5,000) "Electrokinetic Flow Design for Micro-Laboratories on a Chip", NSF, 1999-2002,

$400,000(withD.T.Leighton). "Self-Assembly During Evaporation of Colloidal Solutions", Kraft Food, 1999-2002,

$65,000.“EffectsofLocal InterfacialandFlowDynamicsonFoamDryingandCoarsening”, NSF,

2001-2003,$488,000(withJ.Glazier).“ColloidalMicrofluidicsforDiagnosticKits”,BayerDiagnostics,2001,$5,000.“MicrocirculationAnomaliesinMicrogravityBloodFlow”,NASA,2001-2005,$400,000(withA.Ostafin).“Fuel Cell Research”, Army, 2003-2006, $1,600,000 (PI: P. J. McGinn), 10 PI’s with

$290,000towardsmicrofluidicsresearch(withD.T.LeightonandM.J.McCready). “Micro-FuelCells”,21stCenturyFund,StateofIndiana,2004-2006,$1,000,000(PI:P.J.

McGinn).Microfluidicsshare(withD.T.LeightonandM.J.McCready):$300,000.

“Center forMicrofluidics andMedical Diagnostics”, University of Notre Dame, 2003-2007.$400,000.

“ElectromagneticallyControlledSelf-AssemblyofNanoandMicroCollloidsforMiniature

MedicalDiagnoticKits”,NotreDame-ArgonneFrontiersinMaterialScienceGrant,2003-2005,$200,000(withI.Aronson).

“FaradaicMicro-fluidicDevicesforComplexFluids”,NSF,2005-2007,$100,000. “ProteinMicropump”,SHOTInc.,2005-2007,$48,000. “SilicaBeadsforRapidandReversibleVirusandBacteriaTrapping”,ScientiflcMethods

Inc.,2005,$20,000.(EPA-SBIRPhaseI). “RiskassessmentandmanagementoftheGreatLakesspecies”,GreatLakesProtection

Fund,2006-2009,$1,090,000,PI:D.Lodge(withJ.Feder). “Developing and Applying a Portable Real-Time Genetic Probe for Detecting Aquatic

InvasiveSpeciesinShip’sBallast,GreatLakeProtectionFund,2007-2010,$805,000,PI:D.Lodge(withJ.Feder).

“MicrofiltersforNano-AerosolFiltration”,DefenseThreatReductionAgency,2008- 2011,$652,217(withY.Zhu).

“Collaborative Research: Development of a Biofluid Transport, Separation andMolecular Analysis System using Microfluidics and a Miniature MassSpectrometer”,National Science Foundation, 2009-2011, $1,500,000, PI: P. W Bohn(withG.CookeandZ.Ou-yang)jointPurdue-NDproject.“Novelmalaria vaccine targets linked to nutrient and lipid import”.Gates FoundationPhase1,2009-2010,$100,000PI:K.Haldar(withC.McDowell).

“Novel Microsystems for Manipulation and Analysis of Immune Cells," National Science Foundation, 2009-2013, $2,000,000, PI: A. Revzin (with J. Van der Water and T. Pan). “Dielectrophoresis of Nanocolloids: A New Technique for Capturing Biomolecules and Biomarkers”, United States-Israel Binational Science Foundation, 2010-2014, $156,975 (with G. Yossifon and M. Touvia). “A Nanomembrane-Based Nucleic Acid Sensing Platform”, National Science Foundation, 2011-2014, $325,000 (with L.-J. Cheng) “Nanofluidic Pre-concentration Devices for Enhancing the Detection Sensitivity and Selectivity of Biomarkers for Human Performance Monitoring”, Air Force Office of

Scientific Research, 2011-2014, $200,000, PI:N. Swami. “A Rapid and High-Throughput Pathogen RNA Detection System for Dairy Products”, US Department of Agriculture, 2012-2016, $500,000 (with A. Ramachandran, R. Vanapalli, L-J Cheng and S. Senapati.) “Miniature Biosensor Unit for RNA detection of E coli”, US Army Corp of Engineers, 2012-2013, $110,000 (with S. Senapati and S. Shah). “Nanomembrane-Based Nucleic Acid Sensing for Simultaneous Papillomavirus (HPV)

HPV-induced microRNAs in Oropharygeal Cancers”, Walther Cancer Institute, 2012- 2014, $200,000 (with S. Stack) “Develop a Multi-target Sensor to Detect Dengue Serotypes from Infected Mosquitoes”, National Institute of Health, 2014-2017, $418,000 (PI: S. Senapati) “Next-Generation Medical Diagnostic Devices: Phase 1”, Far Eastern, 2015-2016, $200,000. “Dielectrophoretic Assembly of Carbon Nanotubes for Next Generation FET Chips”, IBM, 2015-1016, $150,000 (+$67,000 ND Matching). “Development of a non-PCR RNA-Based Integrated Biosensing Platform for Detection of all four Dengue Virus Serotypes”, Naval Medical Research Center, 2016, $66,000. “A Solid State Nanopore miRNA Quantification Technology”, National Institute of Health, 2016-2019, $600,000. “An Integrated Microfluidics Platform for Rapid and Sensitive Exosome RNA Detection” , National Institute of Health, 2016-2019, $425,000. “Next-Generation Medical Diagnostic Devices: Phase 2”, Far Eastern, 2016-2018, $600,000. “Thermal Evaporation around Optically Excited Functionalized Nanoparticles”, National Science Foundation, 2017-2020, $350,000 (PI: Tengfei Luo). “TheimpactofNanostructureGeometryonPhoto-ThermalEvaporationProcesses”,CASIS(CenterfortheAdvancementofScienceinSpace),2017-2021,$420,000(PI:TengfeiLuo).“SemiSynBio:CardiacMuscle-Cell-BasedCoupleOscillatorNetwork”,2018-2020,$1,125,000NSFand$375,000SRC(PI:PZorlutuna)

Graduate Students Supervised (35 total, 16 Academics in Bold) I.) UniversityofCalifornia,SantaBarbara M. Aluko, Ph.D., 1983, "Multiple-Time-Scale Analysis of Heterogeneous Catalytic

Reaction Systems". Current position:Vice-Chancellor (President), FederalUniversity,Otuoke,BayelsaState,Nigeria.

V. Ravindran, M. S., 1984, "Mathematical Modelling of a Cycling Zone Extraction

Process". A.Lahbabi,Ph.D.,1985,"SolutionofNavier-StokesEquationinPeriodicMedia".Current

position:ProfessoratEcoleNationaledeL'Industrie,Morocco.II.) UniversityofHouston R. Srinivasan, M. S., 1986, "Application of Spectral Methods to Asymmetric BifurcationofFlowFieldsinSymmetricClosedDomains". S.-S.Ni,M.S.,1986,"BubbleFlowinCapillaryTubes". S.-H. Hwang, Ph.D., 1987, "Control ofNonlinear Systems - An Application of Dynamic

Singularity Theory". Current position: Professor at National Cheng Kung University,Taiwan.

E.Boe,Ph.D.,1988,"TheDynamicsandControlofNonlinearSystemsPossessingaLarge

TimeDelay".Currentposition:Vice-PresidentofResearchatPavilion. J. Ratulowski, Ph.D., 1988, "Mathematical Modeling of the Mechanisms of Bubble

Transport in Single Capillaries". Current position: Director of Flow Characterization,SchlumbergerWellService.

S.-M. F. Chiao, Ph.D., 1988, "Viscoelastic Flow in a Cylinder with a Rotating Lid - A

Galerkin/Spectral Formulation". Current position: Professor at Tung Hai University,Taiwan.

III.) UniversityofNotreDame A.K.Singh,M.S.,1990,"TheStabilityofRimmingFlows". S.Ghosh,M.S.,1991,"ChaoticEnhancementofHeatTransfer",Currentposition:Group

leaderoffuelcellprogramatUnitedTechnologies.

T. Prokopiou, Ph.D., 1992, "Nonlinear Waves on Liquid Interfaces". [Joint with M. J.

McCready].Currentposition:OwnerofGnomonconsultingfirm.. C.C.Chen,Ph.D.,1992,"PatternFormationandControl". Currentposition:Professor

andChairofChemicalEngineeringatChong-ChengUniversity,Taiwan. M. Cheng, Ph.D., 1994, "Sideband and Subharmonic Instabilities of Finite-Amplitude

MonochromaticWaves".Currentposition:ResearcheratChevronResearch. C. K. Cheng, M.S., 1994, "Study of Wave Evolution in Gas-Sheared Films and Falling

LiquidFilmsUsingOpticalImaging". S. Kalliadasis Ph.D., 1994, "Self-Similar Interfacial and Wetting Dynamics". Current

position: Professor of Fluid Mechanics, Chemical Engineering Department, ImperialCollege,England.

M. Sangalli, Ph.D., 1995, [Joint with M. J. McCready],"A Study of Weakly Nonlinear

WavesinStratifiedFluid-FluidFlowsandDistributedReactors".Currentposition:SeniorResearchEngineeratUOP.

I.Veretennikov,Ph.D.,1997, "ExperimentalStudyofContact-LineDynamics". Current

position:ResearchEngineer,BrukerUSA. A.Indeikina,Ph.D.,1998,"AveragingoverMultipleandContinuousScales". CurentPosition:Motherandhousewife. R. Roberts, Ph.D., 1998, [Joint withM. J. McCready], "InterfacialWave Behavior and

MassTransferofMulti-FluidFlows".Currentposition:ResearcheratChevron. Y. Ye, Ph.D., 1998, "Instabilities of Thin-Film Waves and Fronts". Current position:

ResearchEngineeratDuPont. V.V.Yuzhakov,Ph.D.,1999,[JointwithA.E.Miller],"ElectrochemicalSelf-Organizaiton

ofOrderedNanoscaleStructures".Currentposition:Manager,BayerDiagnostics. P. Takhistov, M.S., 1999, "Experimental Study of Electro-Hydrodynamic Phenomena".

Currentposition:AssociateProfessoratFoodScienceDept,RutgersUniversity. J. Keith, Ph.D., 2000 [Joint with D. T. Leighton], "Novel Reactor Design for Pollution

Reduction". Shaheen Awardee for best Notre Dame PhD. Notre Dame Saheen BestEngineering PhD Awardee. Current position: Deavenport Professor and Dean ofEngineering,MississippiState.

K.Duginova,M.S.,2002,“SuspensionsinMicro-Channels”.D. Kopelevich Ph.D. 2002, “Transport in Nano-materials due to Thermal Noise and

DeterministicDynamics”.Currentposition:AssociateProfessor,ChemicalEngineering,UniversityofFlorida(2007NSFCareerAwardee).

S.Thamida,Ph.D.2002,“InstabilityMechanismsinMicro-FluidicsandNano-Materials”.

Current position: Assistant Professor, Chemical Engineering, National Institute ofTechnology,Warangal,India.

G. Arya, Ph. D. 2003 (joint with E. J. Maginn), “Molecular Simulation of Transport in

NanoporousMaterial”,Currentposition:AssociateProfessor,MechanicalEngineering,DukeUniversity.

A. Minerick,Ph.D.2003,“MedicalDiagnosticMicrofluidicsandPhysiologicalBloodFlow Dynamics”, Current position: Professor and Associate Dean, ChemicalEngineering, Michigan Tech (2007 NSF Career Awardee), member of NationalAcademyfortheAdvancementofScience.Y. Ben, PhD. 2004, “Nonlinear Electrokinetic Phenomena in MicroDevices”, Currentposition:AssistantProfessor,ChineseAcademyofScience,Beijing.R. Zhou, Ph. D. 2006, “Microfluidics of Micro- and Nano-Colloidal Suspensions:Designing FutureMiniatureDiagnosticDevices”. Current position: Research Engineer,RohmandHaas.P. Wang, Ph. D. 2007, “Electrokinetic Pumping and Spraying at Micro- and Nano-Scales”.Currentposition:ResearchEngineer,Chevron.D.S.Hou,Ph.D.,2008,“DesigningMicrofluidicComponentsforAnalyteConcentratoinand Identification Using AC Electrokinetics”. Current position: Research Engineer,Merck.S. Maheshwari, Ph. D., 2008, “Anomalous Microfluidic Behavior Near SingularInterfaces”.CurrentPosition:ResearchEngineer,SilverbrookResearch,Sydney.ZacharyGagnon,Ph.D.,2009,“IntegratedACElectrokinetics:FundamentalDesignandAnalysis for Portable Cellular andMolecular Diagnostics”. Shaheen Awardee for bestNotreDamePhD.NotreDameSaheenBestEngineeringPhDAwardee.CurrentPosition:AssociateProfessor,ChemicalEngineering,TexasA&M,2014NSFCareerAwardee.Sagnik Basuray, Ph.D. 2011, “Dielectrophoresis and Its Application to BiomedicalDiagnostic Platforms”. Notre Dame Saheen Best Engineering PhD Awardee. Current

position: Assistant Professor, Chemical Engineering, New Jersey Institute ofTechnology.XinguangCheng,Ph.D.2011,“SingularHarmonicsnearaTaylorcone”.Currentposition:Analyst,KemperCorp.Nishant Chetwani, Ph. D. 2011, “AC Electrospray at Interfacial Singularities”. Currentposition:ResearchEngineer,Intel.YunshanWang,Ph.D.2014,“NovelOpticalBiosensors:SingularIntensityAmplificationand Molecular Trapping Enhancement at Nanoscales”. Current position: AssistantProfessor,ChemicalEngineering,UniversityofUtah.

Daniel Taller, Ph.D. 2015 [joint with David Go], “Surface AcousticWaveMicrofluidics:Droplets, Pinned Liquid Films and Biodetection”. Current position: LivermoreNationalLab.

Yu Yan, PhD. 2015. “Non-Equilibrium Ion Transport in Nanofluidic Devices”. Current

position:ResearchEngineer,Google. Gongchen Sun. 2017. “Nonlinear Ionic Circuits and Ionic Memristors for Integrated

LiquidBiopsyChips”,Currentposition:postdoc,GeorgiaTech. StevenMarczak, 2017. “Beyond Equilibrium: Using Ion Concentration Polarization to

EnhancetheDetectionandSelectivityofNucleicAcidsandtheIsolationofExosomes”,Currentposition:Researcher,DefenseIntelligenceAgency.

CurrentPhDStudentsandExpectedGraduationDatesZehaoPan(2019)(BS:MechanicalEngineering,Tsinghua)DiyaLi(2019)(BS:ChemicalEngineering,UPenn)KarlaGonzalez(2019)[jointwithAlanSeabaugh](BS:EE,MonterreyTech)SebastianSensale(2020)[jointwithZhangliPang](BS:Math,Uruguay)ChenguangZhang(2021)(BS:MicroElectronics,PekingUniversity)Vivek(2022)(BS:ChemicalEngineering,IIT)StuartRyanBlood(2023)[jointwithPinarZorlutuna](BSChemicalEngineering,Kentucky)

Post-Docs and Research Professors Supervised (18 total, 15 academics in bold) W.Q.Lu,1984-1986,Currentposition:ResearchFellow,InstituteofMechanics,ChineseAcademyofScience,Beijing.(Retired).L.-H.Chen,1984-1990,Currentposition:Professor,EastChinaUniversityofChemicalTechnology,China.(Retired)EugeneKalaidin,1996-1999,Currentposition:ProfessorandChair,DepartmentofAppliedMathematics,KubanStateUniversity,Russia.P.Takhisotv,2000-2002,Currentposition:AssociateProfessor,FoodScienceDept,RutgersUniversity.J.Wu,2003-2004:Currentposition:AssociateProfessor,ElectricalEngineering,UniversityofTennessee.(2005NSFCareerAwardee.)E.A.Demekhin,1994-2004.Currentposition:Professor,KrasnodarUniversity,Russia.D.Lastochkin,2003-2005.Currentposition:Post-docatUniversityofNotreDame.L.Yeo,2003-2005:Currentposition:Professor,MechanicalEngineering,RoyalMelbourneInstituteofTechnology,Australia(2007YoungTallPoppyAwardforTopYoungAustralianAcademic).Z.Chen,2004-2007.Currentposition:LuojiaChairProfessor,AssociateDean, PharmaceuticalCollege,WuhanUniversity,China.S.Sengupta,2005-2007Currentposition:AssociateProfessor,BioengineeringDepartment,

UniversityofMissouri,Columbia.G.Yossifon,2007-2009.Currentposition:AssociateProfessor,MechanicalEngineeringDepartment,TechnionUniversity,Israel.R.Kuczinski,2009-2010.Currentposition:ResearchEngineer,GenentechMing Kwan Tan, 2010-2011. Current position: Assistant Professor, Mechanical Engineering,

SwinburneUniversity,Sarawak,Malaysia.JennyHo,2010.Currentposition:Start-up,Singapore.

Z.Slouka,2009-2011,2012-2014.Currentposition:AssociateProfessor,ChemicalEngineering,PragueInstituteofTechnology,CzechRepublic.

LarryLi-JingCheng,2010-2013(ResearchProfessor)Currentposition:AssistantProfessor,ElectricalEngineering,OregonState.ShoupengLiu,2013-2014(Postdoc)Currentposition:AssociateFellow,SouzhouInstituteofBiomedicalEngineeringandTechnology,ChineseAcademyofScience.YongfanMen,2014-16(Postdoc)Currentposition:AssistantProfessor,ShenzhenInstituteofAdvancedTechnology,ChineseAcademyofScience,Shenzhen,China.JarrodSchiffbauer,2016-17(Postdoc)Currentposition:Instructor,ColoradoMesaSunnyShah,2010-2017(Postdoc,ResearchScientist)Currentposition:CurrentPostdocs,SeniorScientistsandResearchProfessorsS.Senapati,2007-Present(ResearchProfessor)CemingWang,2015-Present(PostDoc)ZeinabRamshani,2016-Present(Postdoc)ZeYin,2017-Present(Postdoc)Undergraduate Researchers and Visiting Students Undergrad. GraduateName Year University Subject SchoolTantoHartono 1988-89 NotreDame ChaoticDynamicsofaSurgeTank CaltechGraceSu 1991-92 Michigan FallingFilmWaveDynamics UCLASee-EngPham 1993-95 Cornell ColloidalRheology PrincetonAbhishekAgarwal 1995-97 Purdue RivuletDynamics Wisconsin(EE) CarolinaWu 1997-99 NotreDame FractalDewetting CornellKathyWu 1997-98 Stanford CorrosionDynamics IndustryEricSherer 1997-00 Caltech CrystallizationPatterns, Purdue CorrosionDynamicsandFast IgnitingCatalyticConvertersAlisonWeltner 1999-01 NotreDame PhysiodogicalDynamicsofaFish, Industry DNASequencingwithWaveletsJustinBurt2001-02NotreDameMicrofluidicsforDiagnosticKits TexasKimHatley 2004-05NotreDameBiotissueforDrugEncapsulation IndustryAndyDownard2004-05NotreDameMicrofluidicsandTechTransfer CaltechMikeCoogan2005-06NotreDameBacteriaDetection Industry

WenTaoLuo2005-06NotreDameMicrofluidics IndustryKoreyChu2005-08NotreDameMicrofluidics IndustryDonnyPutra2006-07NotreDameCNTSensors HopkinsAndyAijia 2007-08NotreDameCNTImpedance UCLAPatrickKuscik2008-09NotreDameGeneticDiagnostics MedSchoolPeterMusheheimer2008-10NotreDameNanoslotElectrokinetics WisconsinBryanCaufield2008-09NotreDameGeneticDiagnostics IndustryLaurenFloccare2008-09NotreDameNanocolloidDEP IndustryYunshanWang2008PekingUnivNanofabricationNotreDameThomasHagan2009-10NotreDameNanocolloidImpedanceUCSanDiegoAndrewLoza2009-10NotreDameRNASensingWashingtonU.MedSchoolAndrewChapouros2009-11NotreDameDNASensing IndustryDavidRiehm 2009-11NotreDameSolarCellsMinnesotaPaulScheel 2010-11NotreDameProteinSensingNorthwesternMedicalSch.TruongPham2011-12NotreDamePhotoconductiveSensingMinnesotaChristineRusting2011-12NotreDameNanoporousMembraneSensorIndustryAndrewAyoob2011-12NotreDameProteomicMassSpectrometryHarvardNickRodriguez2011-12NotreDameMembraneSensorNorthwesternDarioMazza2012ImperialPhotoconductiveSensing ImperialMarkSonderman2012NotreDameMembraneSensor IndustryNicholasSchmeidler2012NotreDameMembraneSensor IndustrySaraDale2012NotreDameSurfaceAcousticWaveMassSpect IndustryNicoleMcMillan2012NotreDameMembraneSensor IndustryAnnieShepherd2013NotreDameMembraneSensor IndustryRobinLawler2013NotreDameMembraneSensorGeorgiaTechChrisWalker2013NotreDameMembraneSensorNorthCarolinaStateHongtanDu2013PekingUniv.NanofunnelAgglutinationPekingUnivDidiShe2013PekingUniv.SiConePlasmonicsUnivofPennBihanZhu2013NotreDameNanoconeArrayCornellKarlaGonzalez2013MontereyTec.ACElectrospinningNotreDameAndrewChang2013ChungChengIntegratedChipPostDocKatelinHansen2014NotreDameMembraneSensorIndustryDavidSchipper2014NotreDameRT-PCRwithConductanceSensorsIndustryYuruiQu2014ZhejiangUnivPositiveGainNanoparticlesZhejiangJiaChloeGao2014FudanMembraneSensorsUCBerkeleyFranklinMejia2014MonterreyTechUpconversionNanoparticlesNotreDameRoseDorfler2014-16NotreDameEndotoxinDetectionFulbright Carnegie-MellonPaulO’Neil2015DublinCityU3DChipFabricationDCUFloraKleicmann2015-16Eotvos,HungarymiRNASeparationPazmonyCatholicElaineSmith2016-17NotreDamedepletionnanoparticleassayIndustryOliviaFrasher2017-NotreDamemembranesensorEllenCathill 2017UCDublintransdermalmicroneedlearrayUCDublin

High-SchoolInternsNameYearHighSchoolSubjectCollege/GraduateSchoolAshokAgarwal1998-99ElkhartWettingPurdue(BS)Wisconsin(PhD)AlexCao2012-2013PennPCRChipNotreDame(BS)RaymondHan2012AdamsFuelCellsUniversityofChicago