Ch18 Pattern Formation – Regeneration

Types of Regeneration:

1. Stem Cells (undifferentiated)

2. Morphallaxis

3. Epimorphosis

4. Compensatory Regeneration (differentiated)

Pattern FormationRegeneration

Epimorphosis

RegenerationEpimorphosis

Limb regeneration - Blastema

What is necessary for limb regeneration?Denerve then amputated ?

Amputation add NGF ?

Nerve transplants in animals which normally lack regeneration:

Newborn Opposum1. Hindlimb Amputation ?2. Supplemental nerve tissue ?

Epimorphosis

Hydra freshwater cnidarian Morphallaxis

Hydra – regeneration gradientsHead Activator vs. Head Inhibitor both from Hypostome

Budding - level of HA at gastric bud

Role of nerves

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head gastric gastric foot

HAHI

Compensatory Regeneration