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Chapter 1515.5 Phospholipids

15.7. Cell Membranes

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What are

Phospholipids?1 x Glycerol (polar)

2 x atty !cid (non"polar)

1 x Phosphoric !cid# $%P&' and

amino alcohol (polar)

ormin a phosphodiester bond *ith lycerol andamino alcohol

Gl cero hos holi ids

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!mino !lcohols

+ ,hree aminoalcohols o-nd inlycerophospholipi

ds are#

choline   ethanolamine serine

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Characteristics oPhospholipids

• Phospholipids are aliphatic molec-les#polar and non"polar at the same time. Canact as..

1. /oaps2. 0m-lsiyers

%. arriers membranes

Polar non"polar

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ecithins3Cephalins are

phosholipids o-nd in•rain34ere tiss-e

• 0 yol6#

sed to em-lsiy the inredients

in do-h# at (non"polar) s-ar8mil68 *ater (polar)

0m-lsi9cation# blendin o ats*ith *ater to orm ahomoeneo-s mixt-re called anem-lsion

 ,ypical em-lsions# mil68 lotion8

do-h

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Cell Membranes

•Composed o a PhospholipidBilayer

• Polar head : nonpolar tailsro-p toether

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ipid ilayer

•;o-ble ro* arranemento phospholipids

•$ydrophilic polarheads ace the*ater phase

(blood3cytosol)•$ydrophobic

nonpolar tailsmoe to center

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l-id Mosaic Model ,heory oMembranes

+ Semipermeable# some s-bstancescan cross the membrane bys<-ee=in bet*een phospholipids or

-se channel molec-les+ Fluidity is essential and is re-lated

by ad>-stin sat-rated3-nsat-rated

! contents dependin to temprane. Cholesterol molec-les 6eepmembranes -id. ! solidi9edmembrane is @deadA

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• Mosaic: composed o phospholipids8proteins8 cholesterol

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ipitor mechanism

 

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