ch. 11.6 notes mutations
DESCRIPTION
Ch. 11.6 Notes Mutations. Page 242. deciding what you will look like. It would change the cell’s function and could change what you look like. (for example: you might get a new freckle.). Mutations!. any change in the nucleotide (base-pair) order in DNA. AGTAT. Protein Synthesis. - PowerPoint PPT PresentationTRANSCRIPT
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Ch. 11.6 NotesCh. 11.6 NotesMutations Mutations Page
242
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The Big Picture
Proteins control the cell’s function by __________________________________________.What would happen if there was a sudden change in the type of protein made?
How could this happen?
deciding what you will look like.
It would change the cell’s function and could change what you look like.
(for example: you might get a new freckle.) Mutatio
ns!
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Mutation
Example:Normal:Mutated:
What is it?
Mutations can be caused by what 3 processes that involve DNA? (we’ve already learned them)
1. 3.2.If you have a mutation, what does that mean?
Some examples:
any change in the nucleotide (base-pair) order in DNA
Protein SynthesisCell Division
DNA Replication
It will change what you look like
cancer, birth mark or mole, hair loss, freckles, grey hair, two different colored eyes
AGTAT
AGTTT
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Mutations affect what you Mutations affect what you look like…look like…
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Hollywood’s mutations…Hollywood’s mutations…
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Gene What is a gene?
Where are genes found?
Categories of Mutations
There are two main types of mutations:
1.
2.
Information about a trait you have (like hair color, eye color, etc.)
on DNA
Chromosomal – A change in the whole chromosome/DNA (it affects many genes)
Gene– A change in a very small piece of a chromosome/DNA (it affects only one gene)
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Deletion (on page 252)
Mutation category:Definition:
*ExampleDNA: AAG TCC TGA CTAProtein: THE DOG HATES CATS
Mutated DNA: AAG TCC CTAProtein: THE DOG CATS
ChromosomalA piece of the DNA is
broken off and lost
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Duplication Mutation category:Definition:
*ExampleDNA: AAG TCC TGA CTAProtein: THE DOG HATES CATS
Mutated DNA: AAG TCC TGA TGA CTA
Protein: THE DOG HATES HATES CATS
ChromosomalA piece of DNA is
copied and repeated
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Translocation
Mutation category:Definition:
*ExampleDNA #1: AAG TCC TGA CTAProtein #1: THE DOG HATES CATS
DNA #2 : TAG GGG CCC AATProtein #2: HORSES LIKE TO RUN
Mutated DNA #1: AAG TCC CCC AATMutated Protein #1: THE DOG TO RUN
Mutated DNA #2 : TAG GGG TGA CTAMutated Protein #2: HORSES LIKE HATES CATS
ChromosomalInvolves two chromosomes
– one piece breaks off & switches chromosomes
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Inversion Mutation category:Definition:
*ExampleDNA: AAG TCC TGA CTAProtein: THE DOG HATES CATS
Mutated DNA: AAG TCC ATC AGTMutated Protein: THE DOG SNAKE EAT
ChromosomalA piece of a chromosome
breaks off and reverses order
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Point Mutation
Mutation category:Definition:
*ExampleDNA: AAG TTC T GA CTAProtein: THE DOG HATES CATS
Mutated DNA: AAG TTC CGA CTAMutated Protein: THE DOG LOVES CATS
Gene
One nucleotide (base) is substituted for another
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Frameshift Mutation
Mutation category:Definition:
*ExampleDNA: AAG TCC TGA CTAProtein: THE DOG HATES CATS
Deleted Base G: AAT TCC GAC TAMutated Protein: YOU BIRD RAT ----Added Base C: AAG CTC CTG ACT AMutated Protein: THE ROOSTER EATS STAR ---
ChromosomalAn addition or deletion
of one base that causes the rest to shift over
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Frameshift MutationFrameshift Mutation