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Central nervous system • CNS • Brain -divisions – Hypothalamus – Medulla oblongata – Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock of mammals

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Page 1: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Central nervous system

• CNS

• Brain -divisions– Hypothalamus– Medulla oblongata– Cerebellum

Suprachiasmatic nucleus in hypothalamus is major circadian clock of mammals

Page 2: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.4 Nervous systems of different phyla (Part 1)

Page 3: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.4 Nervous systems of different phyla (Part 2)

Page 4: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.6 The organization of a vertebrate central nervous system

Page 5: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

The central nervous system

• Begins as a hollow tuve

• Embryonic development- 5 regions• Telencephalon• Diencephalon• Mesencephalon• Metencephalon• myelencephalon

Page 6: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.8 A schematic of vertebrate brain structure

Page 7: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock
Page 8: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Evolution of the vertebrate brain

Page 9: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock
Page 10: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock
Page 11: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.9 Localization of function in the mammalian brain: old and current views (Part 1)

Page 12: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Cerebrum

• 2 hemispheres– Outer gray matter– Inner white matter

• Specialization of functions• Left hemisphere

– Dominant in language and analytical ability

• Right hemisphere– Pattern recognition,

• Communication between hemisphere– Corpus callosum

Page 13: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.9 Localization of function in the mammalian brain: old and current views (Part 2)

Page 14: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Cerebral Lateralization

• Cerebral dominance:– Specialization of one

hemisphere.

• Left hemisphere: – More adept in language

and analytical abilities.– Damage:

• Severe speech problems.

• Right hemisphere: – Most adept at visuospatial

tasks.– Damage:

• Difficulty finding way around house.

Page 15: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.10 Functional neuroimaging demonstrates localization of function in cerebral cortex

Page 16: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.11 Maps in the human brain (Part 1)

Page 17: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.11 Maps in the human brain (Part 2)

Page 18: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Homeostatic role of hypothalamus

• Autonomic control center• Center for emotional response and behavior• Body temperature regulation• Regulation of food intake- satiety and hunger

center• Regulation of water balance and thirst • Regulation of sleep-wake cycle• Control of endocrine systems

Page 19: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Pituitary Gland

• Posterior pituitary:– Stores and releases ADH (vasopressin) and

oxytocin.

• Hypothalamus produces releasing and inhibiting hormones that are transported to anterior pituitary.– Regulate secretions of anterior hormones.

• Anterior pituitary:– Regulates secretion of hormones of other endocrine

glands.

Page 20: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Role of medulla oblongata – maintain homeostasis

• Cardiac and vasomotor center– Adjust force and rate of heart contraction– Regulate blood pressure by acting on smooth

muscle of blood vessels

• Respiratory center– Control rate and depth of breathing

• Other regulatory activities– Vomiting, hiccupping, swallowing, coughing,

sneezing ….. etc

Page 21: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Role of cerebellum

• Process inputs received from the motor cortex, brain stem nuclei, and sensory receptors

• Provide precise timing and appropriate patterns of skeletal muscle contraction

• Needed for smooth coordinated movements

• Needed for equilibrium

Page 22: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.17 Suprachiasmatic nucleus in hypothalamus is major circadian clock of mammals (Part 1)

Page 23: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock
Page 24: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.14 Daily rhythm of several physiological functions in a human

Page 25: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.15 Circadian rhythm of metabolic rate and motor activity for a chaffinch (Part 1)

Page 26: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.15 Circadian rhythm of metabolic rate and motor activity for a chaffinch (Part 2)

Page 27: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.16 Activity rhythms of two nocturnal flying squirrels (Glaucomys volans)

Page 28: Central nervous system CNS Brain -divisions –Hypothalamus –Medulla oblongata –Cerebellum Suprachiasmatic nucleus in hypothalamus is major circadian clock

Figure 10.17 Suprachiasmatic nucleus in hypothalamus is major circadian clock of mammals (Part 2)