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CARDIOMETABOLIC DISEASES
A Predictive Metabolic Signature for the Transition from Gestational Diabetes to Type 2 Diabetes
Allalou et al., 2016
View abstract
A single night of sleep curtailment increases plasma acylcarnitines: novel insights in the relationship between
sleep and insulin resistance
Van den Berg et al., 2015
View abstract
Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota
Geurts et al., 2015
View abstract
Alterations in Human Liver Metabolome during Prolonged Cryostorage
Abuja et al., 2015
View abstract
Alterations of the Lipid Metabolome in Dairy Cows Experiencing Excessive Lipolysis Early Postpartum
Humer et al., 2016
View abstract
Amino acids, lipid metabolites, and ferritin as potential mediators linking red meat consumption to type 2
diabetes
Wittenbecher et al., 2015
View abstract
Antiandrogenic therapy with finasteride attenuates cardiac hypertrophy and left ventricular dysfunction
Zwadlo et al., 2015
View abstract
Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal
function in chronic kidney disease
Nkuipou-Kenfack et al., 2014
View abstract
Association between Metabolite Profiles, Metabolic Syndrome and Obesity Status.
Allam-Ndoul et al., 2016
View abstract
Association of Metabolites with Obesity and Type 2 Diabetes Based on FTO Genotype
Kim et al., 2016
View abstract
Associations among plasma metabolite levels and short-term exposure to PM2.5 and ozone in a cardiac
catheterization cohort
Breitner et al., 2016
View abstract
Associations between branched chain amino acid levels, obesity and cardiometabolic complications
Allam-Ndoul et al., 2015
View abstract
Attenuation of Postoperative Acute Liver Failure by Mesenchymal Stem Cell Treatment Due to Metabolic
Implications
Tautenhahn et al., 2015
View abstract
Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice
Franko et al., 2016
View abstract
Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease
Mouzaki et al., 2016
View abstract
BiomarCaRE: rationale and design of the European BiomarCaRE project including 300,000 participants from 13
European countries.
Zeller et al., 2014
View abstract
Blood, urine and faecal metabolite profiles in the study of adult renal disease
Barrios et al., 2015
View abstract
Cardiovascular Risk Factors Associated with Blood Metabolite Concentrations and Their Alterations over a 4-
Year Period in a Population-Based Cohort
Lacruz et al., 2016
Circulation: Cardiovascular Genetics
View abstract
Changes in metabolite profiles caused by genetically determined obesity in mice
Schäfer et al., 2014
View abstract
Changes in the serum metabolite profile in obese children with weight loss
Reinehr et al., 2014
View abstract
Circulating Lysophosphatidylcholines Are Markers of a Metabolically Benign Nonalcoholic Fatty Liver
Lehmann et al., 2013
Diabetes Care 2013, 36 (8), 2331–2338.
View abstract
Clinical and Metabolic Characterization of Lean Caucasian Subjects With Non-alcoholic Fatty Liver
Feldman et al., 2016
View abstract
Comparative Analysis and Modeling of the Severity of Steatohepatitis in DDC-Treated Mouse Strains
Pandey et al., 2014
View abstract
Deletion of mouse Alkbh7 leads to obesity
Solberg et al., 2013
J Mol Cell Biol 2013, 5 (3), 194–203.
View abstract
Detecting Renal Allograft Inflammation Using Quantitative Urine Metabolomics and CXCL10
Ho et al., 2016
View abstract
Di-(2-Ethylhexyl)-Phthalate (DEHP) Causes Impaired Adipocyte Function and Alters Serum Metabolites
Klöting et al., 2015
View abstract
Diagnosing Fatty Liver Disease: A Comparative Evaluation of Metabolic Markers, Phenotypes, Genotypes and
Established Biomarkers
Siegert et al., 2013
PLoS ONE 2013, 8 (10), e76813.
View abstract
Differences in metabolomic and transcriptomic profiles between responders and non-responders to an n-3
polyunsaturated fatty acids
Rudkowska et al., 2013
Genes Nutr 2013, 8 (4), 411–423.
View abstract
Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological
significance
Ferrannini et al., 2013
Diabetes 2013, 62 (5), 1730–1737.
View abstract
Early metabolomics changes in heart and plasma during chronic doxorubicin treatment in B6C3F1 mice.
Schnackenberg et al., 2016
View abstract
Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes
Xu et al., 2015
View abstract
Effects of multiple ascending doses of the glucagon receptor antagonist, PF-06291874, in patients with type 2
diabetes mellitus
Kazierad et al., 2016
View abstract
Endothelin-1 Overexpression Improves Renal Function in eNOS Knockout Mice
Tsuprykov et al., 2015
View abstract
Enzymatically Modified Starch Ameliorates Postprandial Serum Triglycerides and Lipid Metabolome in Growing
Pigs
Metzler-Zebeli et al., 2015
View abstract
Evaluation of various biomarkers as potential mediators of the association between coffee consumption and
incident type 2 diabetes in the EPIC-Potsdam Study.
Jacobs et al., 2014
View abstract
Experimental Glomerular Endothelial Injury In Vivo
Haddad et al., 2013
PLoS ONE 2013, 8 (10), e78244.
View abstract
Exploring the Links between Diet and Health in an Irish Cohort: A Lipidomic Approach
O'Gorman et al., 2017
Journal of Proteome Research
View abstract
Genetically engineered pig models for diabetes research
Wolf et al., 2014
View abstract
Heart-Specific Knockout of the Mitochondrial Thioredoxin Reductase (Txnrd2) Induces Metabolic and Contractile
Dysfunction in the Aging Myocardium
Kiermayer et al., 2015
View abstract
High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede
the development of hepatic insulin resistance in mice.
Kahle et al., 2015
View abstract
Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic
Approach
Floegel et al., 2013
Diabetes 2013, 62 (2), 639–648.
View abstract
Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner
syndrome protein helicase
Aumailley et al., 2015
View abstract
Impaired Bile Acid Homeostasis in Children with Severe Acute Malnutrition
Zhang et al., 2016
View abstract
Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers
Ward-Caviness et al., 2017
Heart
View abstract
Increased amino acids levels and the risk of developing of hypertriglyceridemia in a 7-year follow-up
Mook et al., 2014
View abstract
Increased urine acylcarnitines in diabetic ApoE-/- mice: Hydroxytetradecadienoylcarnitine (C14:2-OH) reflects
diabetic nephropathy in a context of hyperlipidemia
Mirzoyan et al., 2017
Biochemical and Biophysical Research Communications
View abstract
Incretin actions and consequences of incretin-based therapies: lessons from complementary animal models
Renner et al., 2015
View abstract
Integrative 1H-NMR-based Metabolomic Profiling to Identify Type-2 Diabetes Biomarkers: An Application to a
Population of Qatar
Shahzad & Ullah, 2015
View abstract
Lactation is associated with altered metabolomic signatures in women with gestational diabetes
Much et al., 2016
View abstract
Leptin, acylcarnitine metabolites and development of adiposity in the Rhea mother–child cohort in Crete, Greece
Perng et al., 2016
Obesity Science & Practice
View abstract
Leucine Supplementation Protects from Insulin Resistance by Regulating Adiposity Levels
Binder et al., 2013
PLoS ONE 2013, 8 (9), e74705.
View abstract
Linking diet, physical activity, cardiorespiratory fitness and obesity to serum metabolite networks: findings from a
population-based study
Floegel et al., 2014
View abstract
Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse
Vehmas et al., 2015
View abstract
Liver Metabolomics Reveals Increased Oxidative Stress and Fibrogenic Potential in Gfrp Transgenic Mice in
Response to Ionizing Radiation
Cheema et al., 2014
View abstract
Loss of the RNA polymerase III repressor MAF1 confers obesity resistance
Bonhoure et al., 2015
View abstract
Maternal cytokine status may prime the metabolic profile and increase risk for obesity in children
Englich et al., 2017
International Journal of Obesity
View abstract
Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein
and Wrn Null Mice
Aumailley et al., 2015
View abstract
Metabolic disturbances identified in plasma are associated with outcomes in patients with heart failure:
diagnostic and prognostic value of metabolomics
Cheng et al., 2015
View abstract
Metabolic profile provides prognostic value better than galectin-3 in patients with heart failure
Wang et al., 2017
Journal of Cardiology
View abstract
Metabolic Profiles during an Oral Glucose Tolerance Test in Pregnant Women with and without Gestational
Diabetes
Lehmann et al., 2015
View abstract
Metabolic Signature of Remote Ischemic Preconditioning Involving a Cocktail of Amino Acids and Biogenic
Amines
Chao de la Barca et al., 2016
View abstract
Metabolic signatures of cultured human adipocytes from metabolically healthy versus unhealthy obese
individuals
Böhm et al., 2014
View abstract
Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis
Halama et al., 2015
View abstract
Metabolite profiles in heart failure: looking for unique signatures in a heterogeneous syndrome.
Wang & Gupta, 2015
View abstract
Metabolites associate with kidney function decline and incident chronic kidney disease in the general population
Goek et al., 2013
Nephrol. Dial. Transplant. 2013, 28 (8), 2131–2138.
View abstract
Metabolomic biomarkers correlating with hepatic lipidosis in dairy cows
Imhasly et al., 2014
View abstract
Metabolomic Biomarkers for Obesity in Humans
Rauschert et al., 2014
View abstract
Metabolomic distinction of microvascular effects of lipoprotein apheresis e A pilot study
Reimann et al., 2013
Atheroscler Suppl 2013, 14 (1)
View abstract
Metabolomic fingerprint of heart failure with preserved ejection fraction
Zordoky et al., 2015
View abstract
Metabolomic prediction of fetal congenital heart defect in the first trimester
Bahado-Singh et al., 2014
View abstract
Metabolomic profiles of lipid metabolism, arterial stiffness and hemodynamics in male coronary artery disease
patients
Paapstel et al., 2016
View abstract
Metabolomic profiling identifies potential pathways involved in the interaction of iron homeostasis with glucose
metabolism
Stechemesser et al., 2016
Molecular Metabolism
View abstract
Metabolomic profiling in patients undergoing Off-Pump or On-Pump coronary artery bypass surgery
Kirov et al., 2017
BMC Cardiovascular Disorders
View abstract
Metabolomic profiling of ascending thoracic aortic aneurysms and dissections - Implications for pathophysiology
and biomarker discovery
Doppler et al., 2017
PLOS One
View abstract
Metabolomic signature of Coronary Artery Disease in Type 2 Diabetes Mellitus
Stratmann et al., 2016
View abstract
Metabolomics Reveals New Mechanisms for Pathogenesis in Barth Syndrome and Introduces Novel Roles for
Cardiolipin in Cellular Function
Sandlers et al., 2016
View abstract
Metabolomics reveals the sex-specific effects of the SORT1 low-density lipoprotein cholesterol locus in healthy
young adults
Klein et al., 2014
View abstract
Methyl-donor supplementation in obese mice prevents the progression of NAFLD, activates AMPK and
decreases acyl-carnitine levels
Dahlhoff et al., 2014
View abstract
Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E−/− mice
Ryan et al., 2017
Microbiome
View abstract
Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-
alcoholic steatohepatitis
Schröder et al., 2016
View abstract
Nephron-Specific Deletion of Circadian Clock Gene Bmal1 Alters the Plasma and Renal Metabolome and
Impairs Drug Disposition
Nikolaeva et al., 2016
View abstract
Oxidative stress in hypobaric hypoxia and influence on vessel-tone modifying mediators
Pichler et al., 2013
High Alt. Med. Biol. 2013, 14 (3), 273–279.
View abstract
Plasma and urinary amino acid metabolomic profiling in patients with different levels of kidney function
Duranton et al., 2014
View abstract
Plasma Metabolomics reveal Alterations of Sphingo- and Glycerophospholipid Levels in Non-Diabetic Carriers of
the Transcription Factor 7-Like 2 Polymorphism rs7903146
Then et al., 2013
PLoS ONE 2013, 8 (10), e78430.
View abstract
Postpartum outcomes in women with gestational diabetes and their offspring: POGO study design and first-year
results
Hummel et al., 2013
View abstract
Prognostic clinical and molecular biomarkers of renal disease in type 2 diabetes
Pena et al., 2015
View abstract
Rapid Growth and Childhood Obesity Are Strongly Associated with LysoPC(14
Rzehak et al., 2014
View abstract
Relationship between the lipidome, inflammatory markers and insulin resistance
Wallace et al., 2014
View abstract
Serum metabolic biomarkers distinguish metabolically healthy peripherally obese from unhealthy centrally obese
individuals
Gao et al., 2016
View abstract
Serum metabolites predict response to angiotensin II receptor blockers in patients with diabetes mellitus
Pena et al., 2016
View abstract
Serum metabolites related to cardiorespiratory fitness, physical activity energy expenditure, sedentary time and
vigorous activity
Wientzek et al., 2014
View abstract
Specific Metabolic Markers Are Associated with Future Waist-Gaining Phenotype in Women
Merz et al., 2016
View abstract
Specific metabolic profiles and their relationship to insulin resistance in recent-onset type-1 and type-2 diabetes
Knebel et al., 2016
View abstract
Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity
in children
Bhattacharyya et al., 2014
View abstract
The ACTN3 R577X Polymorphism Is Associated with Cardiometabolic Fitness in Healthy Young Adults
Deschamps et al., 2015
View abstract
The Hoorn Diabetes Care System (DCS) cohort. A prospective cohort of persons with type 2 diabetes treated in
primary care in the Netherlands
van der Hejden et al., 2017
BMJ Open
View abstract
Treatment with beta-blockers is associated with lower levels of Lp-PLA2 and suPAR in carotid plaques
Asciutto et al., 2013
Cardiovasc. Pathol. 2013, 22 (6), 438–443.
View abstract
Type 2 diabetes is associated with postprandial amino acid measures
Mook-Kanamori et al., 2015
View abstract
Tyrosine Is Associated with Insulin Resistance in Longitudinal Metabolomic Profiling of Obese Children
Hellmuth et al., 2015
View abstract
Uncovering Factors Related to Pancreatic Beta-Cell Function
Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study
Niewczas et al., 2014
View abstract
Urinary Metabolomics for Noninvasive Detection of Borderline and Acute T Cell-Mediated Rejection in Children
After Kidney Transplantation
Blydt-Hansen et al., 2014
View abstract
Urine and plasma metabolites predict the development of diabetic nephropathy in individuals with Type 2
diabetes mellitus
Pena et al., 2014
View abstract
Variation of serum metabolites related to habitual diet: a targeted metabolomic approach in EPIC-Potsdam
Floegel et al., 2013
Eur J Clin Nutr 2013, 67 (10), 1100–1108.
View abstract
NEUROLOGY
1H NMR derived metabolomic profile of neonatal asphyxia in umbilical cord serum: implications for hypoxic
ischemic encephalopathy
Reinke et al., 2013
J. Proteome Res. 2013, 12 (9), 4230–4239.
View abstract
Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy
Ruiz et al., 2015
View abstract
Alzheimer's disease (AD)-like pathology has discontinuous effects on the brain and blood metabolome
Pan, 2017
Alzheimer's disease-like pathology has transient effects on the brain and blood metabolome
Pan et al., 2015
View abstract
Blood metabolite markers of neocortical amyloid-β burden: discovery and enrichment using candidate proteins
Voyle et al., 2016
View abstract
Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older
individuals
Casanova et al., 2016
View abstract
Combined Metabolomics and Transcriptomics Approaches to Assess the IL-6 Blockade as a Therapeutic of
ALS: Deleterious Alteration of Lipid Metabolism
Patin et al., 2016
View abstract
Defects in fatty acid amide hydrolase 2 in a male with neurologic and psychiatric symptoms
Sirrs et al., 2015
View abstract
Discovery and Validation of Plasma Biomarkers for Major Depressive Disorder Classification Based on Liquid
Chromatography-Mass Spectrometry
Liu et al., 2015
View abstract
Effect of sleep deprivation on the human metabolome.
Davies et al., 2014
View abstract
Effects of Perfluorooctanoic Acid on Metabolic Profiles in Brain and Liver of Mouse Revealed by a High-
throughput Targeted Metabolomics Approach
Yu et al., 2016
View abstract
Inflammation in adult women with a history of child maltreatment: The involvement of mitochondrial alterations
and oxidative stress
Boeck et al., 2016
View abstract
Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine
metabolism in Huntington's disease peripheral blood samples
Mastrokolias et al., 2016
View abstract
Lack of Sterol Regulatory Element Binding Factor-1c Imposes Glial Fatty Acid Utilization Leading to Peripheral
Neuropathy
Cermenati et al., 2015
View abstract
Metabolic Disturbances in Plasma as Biomarkers for Huntington’s Disease
Cheng et al., 2016
View abstract
Metabolic Modifications in Human Biofluids Suggest the Involvement of Sphingolipid, Antioxidant, and Glutamate
Metabolism in Alzheimer's Disease Pathogenesis
Ellis et al., 2015
View abstract
Metabolic network failures in Alzheimer’s disease—A biochemical road map
Toledo et al., 2017
Alzheimer's & Dementia
View abstract
Metabolic profiling of presymptomatic Huntington’s disease sheep reveals novel biomarkers
Skene et al., 2017
Scientific Reports
View abstract
Metabolomic profiles in individuals with negative affectivity and social inhibition: A population-based study of
Type D personality. Psychoneuroendocrinology
Altmaier et al., 2013
Psychoneuroendocrinology 2013, 38 (8), 1299–1309.
View abstract
Persistently Altered Metabolic Phenotype following Perinatal Excitotoxic Brain Injury
Blaise et al., 2017
Developmental Neuroscience
View abstract
Plasma 24-metabolite Panel Predicts Preclinical Transition to Clinical Stages of Alzheimer's Disease
Fiandaca et al., 2015
View abstract
Plasma phospholipids and prevalence of mild cognitive impairment and/or dementia in the ARIC Neurocognitive
Study (ARIC-NCS)
Li et al., 2016
View abstract
Plasma phospholipids identify antecedent memory impairment in older adults
Mapstone et al., 2014
Nature Medicine
View abstract
Protection of Brain Injury by Amniotic Mesenchymal Stromal Cell-Secreted Metabolites
Pischiutta et al., 2016
View abstract
Serum metabolomic markers for traumatic brain injury: a mouse model.
Bahado-Singh et al., 2016
View abstract
Short-term cuprizone feeding induces selective amino acid deprivation with concomitant activation of an
integrated stress response in
Goldberg et al., 2013
Cell. Mol. Neurobiol. 2013, 33 (8), 1087–1098.
View abstract
Sphingomyelin SM(d18:1/18:0) is Significantly Enhanced in Cerebrospinal Fluid Samples Dichotomized by
Pathological Amyloid-β42, Tau, and Phospho-Tau-181 Levels
Koal et al., 2014
View abstract
Taurine and Epidermal Growth Factor Belong to the Signature of First-Episode Psychosis
Koido et al., 2016
View abstract
The Brain Metabolome of Male Rats across the Lifespan
Zheng et al., 2016
View abstract
The Brain Metabolome of Male Rats across the Lifespan
Zheng et al., 2016
Scientific Reports
View abstract
The metabolomic signature of Leber's hereditary optic neuropathy reveals endoplasmic reticulum stress
Chao de la Barca et al., 2016
View abstract
The ratio of phosphatidylcholines to lysophosphatidylcholines in plasma differentiates healthy controls from
patients with Alzheimer's disease and mild cognitive impairment
Klavins K., Koal T., Dallmann G. et al., 2015
View abstract
Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+)
Krug et al., 2014
View abstract
What success can teach us about failure: the plasma metabolome of older adults with superior memory and
lessons for Alzheimer's disease
Mapstone et al., 2016
Neurobiology of Aging
View abstract
NUTRITION & LIFESTYLE
12-months metabolic changes among gender dysphoric individuals under cross-sex hormone treatment: a
targeted metabolomics study
Auer et al., 2016
Scientific Reports
View abstract
A Postnatal Diet Containing Phospholipids, Processed to Yield Large, Phospholipid-Coated Lipid Droplets,
Affects Specific Cognitive Behaviors in Healthy Male Mice
Schipper et al., 2016
View abstract
A single night of sleep curtailment increases plasma acylcarnitines: novel insights in the relationship between
sleep and insulin resistance
Van den Berg et al., 2015
View abstract
Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota
Geurts et al., 2015
View abstract
Alcohol-induced metabolomic differences in humans
Jaremek et al., 2013
Transl Psychiatry 2013, 3, e276.
View abstract
Amino acids, lipid metabolites, and ferritin as potential mediators linking red meat consumption to type 2
diabetes
Wittenbecher et al., 2015
View abstract
Association of Metabolites with Obesity and Type 2 Diabetes Based on FTO Genotype
Kim et al., 2016
View abstract
Associations between branched chain amino acid levels, obesity and cardiometabolic complications
Allam-Ndoul et al., 2015
View abstract
Associations of anthropometric markers with serum metabolites using a targeted metabolomics approach:
results of the EPIC-potsdam study
Bachlechner et al., 2016
View abstract
Changes in the serum metabolite profile in obese children with weight loss
Reinehr et al., 2014
View abstract
Characterization of Selected Metabolic and Immunologic Markers Following Exclusive Enteral Nutrition of
Pediatric Crohn’s Disease Patients
Brahmbhatt et al., 2016
View abstract
Characterizing Blood Metabolomics Profiles Associated with Self-Reported Food Intakes in Female Twins
Pallister et al., 2016
View abstract
Combined untargeted and targeted metabolomic profiling reveals urinary biomarkers for discriminating obese
from normal-weight adolescents
Cho et al., 2016
View abstract
Constant-load exercise decreases the serum concentration of myeloperoxidase in healthy smokers and smokers
with COPD
Holz et al., 2015
View abstract
Dietary protein intake affects amino acid and acylcarnitine metabolism in infants aged 6 months
Kirchberg et al., 2014
View abstract
Differences in metabolomic and transcriptomic profiles between responders and non-responders to an n-3
polyunsaturated fatty acids
Rudkowska et al., 2013
Genes Nutr 2013, 8 (4), 411–423.
View abstract
Dynamically regulated miRNA-mRNA networks revealed by exercise
Tonevitsky et al., 2013
BMC Physiol. 2013, 13, 9.
View abstract
Effect of sleep deprivation on the human metabolome.
Davies et al., 2014
View abstract
Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort
study
Xu et al., 2013
BMC Med 2013, 11, 60.
View abstract
Effects of Surgical and Dietary Weight Loss Therapy for Obesity on Gut Microbiota Composition and Nutrient
Absorption
Antje, 2014
View abstract
Environmental Enteric Dysfunction is Associated with Carnitine Deficiency and Altered Fatty Acid Oxidation
Semba et al., 2017
EBiomedicine
View abstract
Enzymatically Modified Starch Ameliorates Postprandial Serum Triglycerides and Lipid Metabolome in Growing
Pigs
Metzler-Zebeli et al., 2015
View abstract
Evaluation of various biomarkers as potential mediators of the association between coffee consumption and
incident type 2 diabetes in the EPIC-Potsdam Study.
Jacobs et al., 2014
View abstract
Explorative study of metabolic adaptations to various dietary calcium intakes and cereal sources on serum
metabolome and hepatic gene expression in juvenile pigs
Metzler-Zebeli et al., 2015
View abstract
Exploring the Links between Diet and Health in an Irish Cohort: A Lipidomic Approach
O'Gorman et al., 2017
Journal of Proteome Research
View abstract
Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice
Reis et al., 2016
View abstract
Fecal metabolome of the Hadza hunter-gatherers: a host-microbiome integrative view
Turroni et al., 2016
View abstract
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial
McIntosh et al., 2016
View abstract
Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice.
Missios et al., 2014
View abstract
Habitual dietary intake impacts on the lipidomic profile
O'Gorman et al., 2014
View abstract
High Fat Diet Accelerates Pathogenesis of Murine Crohn’s Disease-Like Ileitis Independently of Obesity
Gruber et al., 2013
PLoS ONE 2013, 8 (8), e71661.
View abstract
High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede
the development of hepatic insulin resistance in mice.
Kahle et al., 2015
View abstract
Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy
Subjects: The Self-Directed Biological Transformation Initiative (SBTI)
Peterson et al., 2016
View abstract
Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic
Approach
Floegel et al., 2013
Diabetes 2013, 62 (2), 639–648.
View abstract
Impact of a western diet on the ovarian and serum metabolome
Dhungana et al., 2016
View abstract
Impaired Bile Acid Homeostasis in Children with Severe Acute Malnutrition
Zhang et al., 2016
View abstract
Intravenous Fish Oil and Pediatric Intestinal Failure–Associated Liver Disease: Changes in Plasma Phytosterols,
Cytokines, and Bile Acids and Erythrocyte Fatty Acids
Calkins et al., 2017
Journal of Enteral and Parenteral Nutrition
View abstract
Lactation is associated with altered metabolomic signatures in women with gestational diabetes
Much et al., 2016
View abstract
Leptin, acylcarnitine metabolites and development of adiposity in the Rhea mother–child cohort in Crete, Greece
Perng et al., 2016
Obesity Science & Practice
View abstract
Leucine Supplementation Protects from Insulin Resistance by Regulating Adiposity Levels
Binder et al., 2013
PLoS ONE 2013, 8 (9), e74705.
View abstract
Linking diet, physical activity, cardiorespiratory fitness and obesity to serum metabolite networks: findings from a
population-based study
Floegel et al., 2014
View abstract
Loss of the RNA polymerase III repressor MAF1 confers obesity resistance
Bonhoure et al., 2015
View abstract
Maternal cytokine status may prime the metabolic profile and increase risk for obesity in children
Englich et al., 2017
International Journal of Obesity
View abstract
Metabolic alterations in children with environmental enteric dysfunction
Semba et al., 2016
View abstract
Metabolic profiles of male meat eaters, fish eaters, vegetarians, and vegans from the EPIC-Oxford cohort
Schmidt et al., 2015
View abstract
Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis
Halama et al., 2015
View abstract
Metabolites of milk intake: a metabolomic approach in UK twins with findings replicated in two European cohorts
Pallister et al., 2016
View abstract
Metabolomic Biomarkers for Obesity in Humans
Rauschert et al., 2014
View abstract
Metabolomic changes in serum of children with different clinical diagnoses of malnutrition
di Giovanni et al., 2016
Journal of Nutrition
View abstract
Metabolomics evidences plasma and serum biomarkers differentiating two heavy pig breeds
Bovo et al., 2016
View abstract
Metabolomics of Ramadan fasting: an opportunity for the controlled study of physiological responses to food
intake
Mathew et al., 2014
View abstract
Metabolomics reveals determinants of weight loss during lifestyle intervention in obese children
Wahl et al., 2013
Metabolomics 2013, 9 (6), 1157–1167.
View abstract
Metabolomics reveals differences in postprandial responses to breads and fasting metabolic characteristics
associated with postprandial insulin demand in postmenopausal women
Moazzami et al., 2014
View abstract
Metabolomics reveals effects of maternal smoking on endogenous metabolites from lipid metabolism in cord
blood of newborns
Rolle-Kampczyk et al., 2016
View abstract
Metabolomics using GC-TOF-MS followed by subsequent GC-FID and HILIC-MS/MS analysis revealed
significantly altered fatty acid and phospholipid species profiles in plasma of smokers
Müller et al., 2014
View abstract
Metabotypes with properly functioning mitochondria and anti-inflammation predict extended productive life span
in dairy cows
Huber et al., 2016
View abstract
Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E−/− mice
Ryan et al., 2017
Microbiome
View abstract
Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-
alcoholic steatohepatitis
Schröder et al., 2016
View abstract
Modeling and Classification of Kinetic Patterns of Dynamic Metabolic Biomarkers in Physical Activity
Breit et al., 2015
View abstract
Modulation of the lipidomic profile due to a lipid challenge and fitness level: a postprandial study.
Morris et al., 2015
View abstract
Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action
Ost et al., 2015
View abstract
Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise
Mera et al., 2016
View abstract
Physical exercise induces specific adaptations resulting in reduced organ injury and mortality during severe
polymicrobial sepsis
Sossdorf et al., 2013
Crit. Care Med. 2013, 41 (10), e246-55.
View abstract
Physiological changes due to mild cooling in healthy lean males of white Caucasian and South Asian descent: a
metabolomics study
Nahon et al., 2015
View abstract
Plasma amino acids and metabolic profiling of dairy cows in response to a bolus duodenal infusion of leucine
Sadri et al., 2017
PLOS ONe
View abstract
Plasma concentrations and intakes of amino acids in male meat-eaters, fish-eaters, vegetarians and vegans: a
cross-sectional analysis in the EPIC-Oxford cohort
Schmidt et al., 2015
View abstract
Properties of myenteric neurones and mucosal functions in the distal colon of diet-induced obese mice
Reichardt et al., 2013
View abstract
Rapid Growth and Childhood Obesity Are Strongly Associated with LysoPC(14
Rzehak et al., 2014
View abstract
Serum metabolic biomarkers distinguish metabolically healthy peripherally obese from unhealthy centrally obese
individuals
Gao et al., 2016
View abstract
Serum metabolites related to cardiorespiratory fitness, physical activity energy expenditure, sedentary time and
vigorous activity
Wientzek et al., 2014
View abstract
Specific circulating phospholipids, acylcarnitines, amino acids and biogenic amines are aerobic exercies markers
Felder et al., 2017
Journal of Science and Medicine in Sport
View abstract
Specific Metabolic Markers Are Associated with Future Waist-Gaining Phenotype in Women
Merz et al., 2016
View abstract
Systems biology analysis merging phenotype, metabolomic and genomic data identifies Non-SMC Condensin I
Complex, Subunit G (NCAPG) and cellular maintenance processes as major contributors to genetic variability in
bovine feed efficiency
Widmann et al., 2015
View abstract
Targeted metabolomics profiles are strongly correlated with nutritional patterns in women
Menni et al., 2013
Metabolomics 2013, 9 (2), 506–514.
View abstract
The Application of Metabolomic Profiling to the Effects of Physical Activity
Daskalaki et al., 2015
View abstract
The COLON study: Colorectal cancer: Longitudinal, Observational study on Nutritional and lifestyle factors that
may influence colorectal tumour recurrence, survival and quality of life.
Winkels et al., 2014
View abstract
The effect of coffee intake on lysophosphatidylcholines: A targeted metabolomic approach
Miranda et al., 2016
Clinical Nutrition
View abstract
The Human Early-Life Exposome (HELIX): Project Rationale and Design
Vrijheid et al., 2014
View abstract
The influence of a chronic L-carnitine administration on the plasma metabolome of male Fischer 344 rats
Weinert et al., 2017
Molecular Nutrition
View abstract
The Karlsruhe Metabolomics and Nutrition (KarMeN) Study: Protocol and Methods of a Cross-Sectional Study to
Characterize the Metabolome of Healthy Men and Women
Bub et al., 2016
View abstract
The metabolic signature associated with the Western dietary pattern: a cross-sectional study
Bouchard-Mercier et al., 2013
Nutr J 2013, 12, 158.
View abstract
Transcriptomics and Metabonomics Identify Essential Metabolic Signatures in Calorie Restriction (CR)
Regulation across Multiple Mouse Strains
Collino et al., 2013
View abstract
Transglycosylated Starch Improves Insulin Response and Alters Lipid and Amino Acid Metabolome in a Growing
Pig Model
Newman et al., 2017
Nutrients
View abstract
Type 2 diabetes is associated with postprandial amino acid measures
Mook-Kanamori et al., 2015
View abstract
Tyrosine Is Associated with Insulin Resistance in Longitudinal Metabolomic Profiling of Obese Children
Hellmuth et al., 2015
View abstract
Variation of serum metabolites related to habitual diet: a targeted metabolomic approach in EPIC-Potsdam
Floegel et al., 2013
Eur J Clin Nutr 2013, 67 (10), 1100–1108.
View abstract
ONCOLOGY
Absence of PD-L1 on tumor cells is associated with reduced MHC I expression and PD-L1 expression increases
in recurrent serous ovarian cancer
Aust et al., 2017
Scientific Reports
View abstract
AKT1 and MYC induce distinctive metabolic fingerprints in human prostate cancer
Priolo et al., 2014
View abstract
Alteration of amino acid and biogenic amine metabolism in hepatobiliary cancers: Findings from a prospective
cohort study
Stepien et al., 2016
View abstract
Attenuation of Postoperative Acute Liver Failure by Mesenchymal Stem Cell Treatment Due to Metabolic
Implications
Tautenhahn et al., 2015
View abstract
BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease
metabolism
Wang et al., 2015
View abstract
Biomarker candidates for the detection of an infectious etiology of febrile neutropenia
Richter et al., 2015
View abstract
Combined Proteome and Eicosanoid Profiling Approach for Revealing Implications of Human Fibroblasts in
Chronic Inflammation
Tahir et al., 2017
View abstract
Comparative metabolomic analysis of HPAC cells following the acquisition of erlotinib resistance
Lee et al., 2017
Oncology Letters
View abstract
Comparative metabolomics profiling of isogenic KRAS wild type and mutant NSCLC cells in vitro and in vivo
Brunelli et al., 2016
View abstract
Development of a metabolites risk score for one-year mortality risk prediction in pancreatic adenocarcinoma
patients
Fontana et al., 2016
View abstract
Different metabolic responses to PI3K inhibition in NSCLC cells harboring wild-type and G12C mutant KRAS.
Caiola et al., 2016
View abstract
Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder
Piyarathna et al., 2017
European Urology Focus
View abstract
Distinct Metabolic Signature of Human Bladder Cancer Cells Carrying an Impaired Fanconi Anemia Tumor-
Suppressor Signaling Pathway
Panneerselvam et al., 2016
View abstract
Early metabolomics changes in heart and plasma during chronic doxorubicin treatment in B6C3F1 mice.
Schnackenberg et al., 2016
View abstract
Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested
casecontrol study
Fedirko et al., 2017
BMC Medicine
View abstract
From genotype to functional phenotype: unraveling the metabolomic features of colorectal cancer
Bathe et al., 2014
View abstract
Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells
Belcheva et al., 2014
View abstract
Higher plasma levels of lysophosphatidylcholine 18:0 are related to a lower risk of common cancers in a
prospective metabolomics study
Kühn et al., 2016
View abstract
Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation
Bakiri et al., 2017
Journal of Experimental Medicine
View abstract
Mass Spectrometry-Based Quantitative Metabolomics Revealed a Distinct Lipid Profile in Breast Cancer
Patients
Qiu et al., 2013
Int J Mol Sci 2013, 14 (4), 8047–8061.
View abstract
Metabolic markers in blood can separate prostate cancer from benign prostatic hyperplasia
Giskeødegård et al., 2015
View abstract
Metabolic pathways promoting cancer cell survival and growth
Boroughs et al., 2016
View abstract
Metabolic Phenotyping Reveals a Lipid Mediator Response to Ionizing Radiation
Laiakis et al., 2014
View abstract
Metabolic signature predicts progression and response after taxane-anthracycline neoadjuvant regimen
Dale et al., 2015
View abstract
Metabolomic profile in pancreatic cancer patients: a consensusbased approach to identify highly discriminating
metabolites
Di Gangi et al., 2015
View abstract
Metabolomics biomarkers of frailty in elderly breast cancer patients
Corona et al., 2014
View abstract
Metabolomics for Biomarker Discovery in Gastroenterological Cancer
Nishiumi et al., 2014
View abstract
Multi-omics analysis of serum samples demonstrates reprogramming of organ functions via systemic calcium
mobilization and platelet activation in metastatic melanoma
Muqaku et al., 2016
View abstract
New circulating lipid markers related to breast cancer
Dale et al., 2015
View abstract
Phamacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers
associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2
positive breast cancer
Miolo et al., 2016
View abstract
Plasma Metabolomic Changes following PI3K Inhibition as Pharmacodynamic Biomarkers: Preclinical Discovery
to Phase I Trial Evaluation.
Ang et al., 2016
View abstract
Pre-diagnostic circulating vitamin D levels and risk of hepatocellular carcinoma in European populations: A
nested case-control study
Fedirko et al., 2014
View abstract
Review of mass spectrometry-based metabolomics in cancer research
Liesenfeld et al., 2013
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
View abstract
Serum lipid alterations identified in chronic hepatitis B, hepatitis B virus-associated cirrhosis and carcinoma
patients
Wu et al., Scientific Reports 2017
Scientific Reports
View abstract
The COLON study: Colorectal cancer: Longitudinal, Observational study on Nutritional and lifestyle factors that
may influence colorectal tumour recurrence, survival and quality of life.
Winkels et al., 2014
View abstract
The Histone Demethylase KDM5 Activates Gene Expression by Recognizing Chromatin Context through Its
PHD Reader Motif
Liu and Secombe, 2015
View abstract
PHARMACEUTICAL RESEARCH
Antiandrogenic therapy with finasteride attenuates cardiac hypertrophy and left ventricular dysfunction
Zwadlo et al., 2015
View abstract
Assessment of serum biomarkers in rats after exposure to pesticides of different chemical classes
Moser et al., 2015
View abstract
Associations among plasma metabolite levels and short-term exposure to PM2.5 and ozone in a cardiac
catheterization cohort
Breitner et al., 2016
View abstract
Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice
Franko et al., 2016
View abstract
Chemical and technical challenges in the analysis of central carbonmetabolites by liquid-chromatography mass
spectrometry
Siegel et al., 2013
View abstract
Combined Metabolomics and Transcriptomics Approaches to Assess the IL-6 Blockade as a Therapeutic of
ALS: Deleterious Alteration of Lipid Metabolism
Patin et al., 2016
View abstract
Comparative Analysis and Modeling of the Severity of Steatohepatitis in DDC-Treated Mouse Strains
Pandey et al., 2014
View abstract
Comparative metabolomic analysis of HPAC cells following the acquisition of erlotinib resistance
Lee et al., 2017
Oncology Letters
View abstract
Comparative metabolomics profiling of isogenic KRAS wild type and mutant NSCLC cells in vitro and in vivo
Brunelli et al., 2016
View abstract
Di-(2-Ethylhexyl)-Phthalate (DEHP) Causes Impaired Adipocyte Function and Alters Serum Metabolites
Klöting et al., 2015
View abstract
Different metabolic responses to PI3K inhibition in NSCLC cells harboring wild-type and G12C mutant KRAS.
Caiola et al., 2016
View abstract
Differential cellular metabolite alterations in HaCaT cells caused by exposure to the aryl hydrocarbon receptor-
binding polycyclic aromatic hydrocarbons chrysene, benzo[a]pyrene and dibenzo[a,l]pyrene
Potratz et al., 2016
View abstract
Early metabolomics changes in heart and plasma during chronic doxorubicin treatment in B6C3F1 mice.
Schnackenberg et al., 2016
View abstract
Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes
Xu et al., 2015
View abstract
Effects of multiple ascending doses of the glucagon receptor antagonist, PF-06291874, in patients with type 2
diabetes mellitus
Kazierad et al., 2016
View abstract
Effects of Perfluorooctanoic Acid on Metabolic Profiles in Brain and Liver of Mouse Revealed by a
Highthroughput Targeted Metabolomics Approach
Yu et al., 2017
Scientific Reports
View abstract
Emerging applications of metabolomics in drug discovery and precision medicine
Wishart 2016
View abstract
Establishing the pathway and time resolved benzo[a]pyrene toxicity on Hepa1c1c7 cells at toxic and subtoxic
exposure
Kalkhof et al., 2014
View abstract
Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy
Subjects: The Self-Directed Biological Transformation Initiative (SBTI)
Peterson et al., 2016
View abstract
Identification of Lipidomic Biomarkers for Coexposure to Subtoxic Doses of Benzo[a]pyrene and Cadmium: The
Toxicological Cascade Biomarker Approach
Jungnickel et al., 2014
View abstract
Increased dosage of AOX1 promoter-regulated expression cassettes leads to transcription attenuation of the
methanol metabolism in Pichia pastoris
Cámara et al., 2017
Scientific Reports
View abstract
Increased efficacy of omalizumab in atopic dermatitis patients with wild-type filaggrin status and higher serum
levels of phosphatidylcholines
Hotze et al., 2014
View abstract
Liver Metabolomics Reveals Increased Oxidative Stress and Fibrogenic Potential in Gfrp Transgenic Mice in
Response to Ionizing Radiation
Cheema et al., 2014
View abstract
Metabolic Dysregulation after Neutron Exposures Expected from an Improvised Nuclear Device
Laiakis et al., 2017
Radiation Research
View abstract
Metabolic Phenotyping Reveals a Lipid Mediator Response to Ionizing Radiation
Laiakis et al., 2014
View abstract
Metabolic signature predicts progression and response after taxane-anthracycline neoadjuvant regimen
Dale et al., 2015
View abstract
Metabolomic-Based Strategies for Anti-Parasite Drug Discovery.
Vincent et al., 2014
View abstract
Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E−/− mice
Ryan et al., 2017
Microbiome
View abstract
Perinatal exposure to glyphosate-based herbicide alters the thyrotrophic axis and causes thyroid hormone
homeostasis imbalance in male rats
de Souza et al., 2017
Toxicology
View abstract
Phamacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers
associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2
positive breast cancer
Miolo et al., 2016
View abstract
Plasma Metabolomic Changes following PI3K Inhibition as Pharmacodynamic Biomarkers: Preclinical Discovery
to Phase I Trial Evaluation.
Ang et al., 2016
View abstract
Proteomic and Metabolomic Analyses Reveal Contrasting Anti-Inflammatory Effects of an Extract of Mucor
Racemosus Secondary Metabolites Compared to Dexamethasone
Meier et al., 2015
View abstract
Quantitative targeted bile acid profiling as new markers for DILI in a model of methapyrilene-induced liver injury
in rats
Slopianka et al., 2017
Toxicology
View abstract
Serum metabolites predict response to angiotensin II receptor blockers in patients with diabetes mellitus
Pena et al., 2016
View abstract
Short-term cuprizone feeding induces selective amino acid deprivation with concomitant activation of an
integrated stress response in
Goldberg et al., 2013
Cell. Mol. Neurobiol. 2013, 33 (8), 1087–1098.
View abstract
Sildenafil Therapy Normalizes the Aberrant Metabolomic Profile in the Comt(-/-) Mouse Model of
Preeclampsia/Fetal Growth Restriction
Stanley et al., 2015
View abstract
Subtoxic concentrations of benzo[a]pyrene induce metabolic changes and oxidative stress in non-activated and
affect the mTOR pathway in activated Jurkat T cells
Baumann et al., 2014
View abstract
Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity
in children
Bhattacharyya et al., 2014
View abstract
Targeted Metabolomic Profiling Indicates Structure-based Perturbations in Serum Phospholipids in Children with
Acetaminophen Overdose
Bhattacharyya et al., 2016
View abstract
Targeted metabolomics of nonhuman primate serum after exposure to ionizing radiation: potential tools for high-
throughput biodosimetry
Pannkuk et al., 2016
View abstract
Taurine and Epidermal Growth Factor Belong to the Signature of First-Episode Psychosis
Koido et al., 2016
View abstract
The effects of early postnatal exposure to a low dose of decabromodiphenyl ether (BDE-209) on serum
metabolites in male mice
Eguchi et al., 2016
View abstract
The influence of a chronic L-carnitine administration on the plasma metabolome of male Fischer 344 rats
Weinert et al., 2017
Molecular Nutrition
View abstract
Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+)
Krug et al., 2014
View abstract
Treatment with beta-blockers is associated with lower levels of Lp-PLA2 and suPAR in carotid plaques
Asciutto et al., 2013
Cardiovasc. Pathol. 2013, 22 (6), 438–443.
View abstract
AGING
Aging-related changes in mouse serum glycerophospholipid profiles
Kim et al., 2014
View abstract
Analytical tools to human assess aging
da Costa et al., 2015
View abstract
Cohort Profile: TwinsUK and healthy ageing twin study
Moayyeri et al., 2013
Int J Epidemiol 2013, 42 (1), 76–85.
View abstract
Effect of sleep deprivation on the human metabolome.
Davies et al., 2014
View abstract
Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice
Reis et al., 2016
View abstract
Heart-Specific Knockout of the Mitochondrial Thioredoxin Reductase (Txnrd2) Induces Metabolic and Contractile
Dysfunction in the Aging Myocardium
Kiermayer et al., 2015
View abstract
Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner
syndrome protein helicase
Aumailley et al., 2015
View abstract
Lysophosphatidylcholines to phosphatidylcholines ratio predicts advanced knee osteoarthritis
Zhang et al., 2016
View abstract
Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein
and Wrn Null Mice
Aumailley et al., 2015
View abstract
Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of
Lipids, Amino Acids, and Gut Microbiota Metabolism
Collino et al., 2013
PLoS ONE 2013, 8 (3), e56564.
View abstract
Metabolomic analysis of human plasma reveals that arginine is depleted in knee osteoarthritis patients
Zhang et al., 2015
View abstract
Metabolomics biomarkers of frailty in elderly breast cancer patients
Corona et al., 2014
View abstract
Plasma Biomarkers of Poor Muscle Quality in Older Men and Women from the Baltimore Longitudinal Study of
Aging
Moaddel et al., 2016
View abstract
Relationship Between Blood Plasma and Synovial Fluid Metabolite Concentrations in Patients with Osteoarthritis
Zhang et al., 2015
View abstract
What success can teach us about failure: the plasma metabolome of older adults with superior memory and
lessons for Alzheimer's disease
Mapstone et al., 2016
Neurobiology of Aging
View abstract
BIOPROCESSING
Disruption of genes involved in CORVET complex leads to enhanced secretion of heterologous
carboxylesterase only in protease deficient Pichia pastoris
Marsalek et al., 2017
Biotechnology Journal
View abstract
Increased dosage of AOX1 promoter-regulated expression cassettes leads to transcription attenuation of the
methanol metabolism in Pichia pastoris
Cámara et al., 2017
Scientific Reports
View abstract
Interlaboratory comparison for quantitative primary metabolite profiling in Pichia pastoris
Klavins et al., 2013
Anal Bioanal Chem 2013, 405 (15), 5159–5169.
View abstract
Investigating the Role of Sphingolipids in Innate Immunity
Koeberlin, 2015
PhD Thesis
Pichia pastoris Aft1 - a novel transcription factor, enhancing recombinant protein secretion.
Ruth et al., 2014
View abstract
Reduced quenching and extraction time for mammalian cells using filtration and syringe extraction
Hernández et al., 2014
View abstract
The Acclimation of Phaeodactylum tricornutum to Blue and Red Light Does Not Influence the Photosynthetic
Light Reaction but Strongly Disturbs the Carbon Allocation Pattern
Jungandreas et al., 2014
View abstract
The secretory pathway: exploring yeast diversity
Delic et al., 2013
FEMS Microbiol. Rev. 2013, 37 (6), 872–914.
View abstract
EPIDEMIOLOGY & GENETICS
Associations between thyroid hormones and serum metabolite profiles in an euthyroid population
Jourdan et al., 2014
View abstract
Cohort Profile: TwinsUK and healthy ageing twin study
Moayyeri et al., 2013
Int J Epidemiol 2013, 42 (1), 76–85.
View abstract
Design and Analysis of Metabolomics Studies in Epidemiologic Research: A Primer on -Omic Technologies.
Tzoulaki et al., 2014
View abstract
Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort
study
Xu et al., 2013
BMC Med 2013, 11, 60.
View abstract
Epigenetics meets metabolomics: An epigenome-wide association study with blood serum metabolic traits
Petersen et al., 2013
View abstract
Exploring the Links between Diet and Health in an Irish Cohort: A Lipidomic Approach
O'Gorman et al., 2017
Journal of Proteome Research
View abstract
Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested
casecontrol study
Fedirko et al., 2017
BMC Medicine
View abstract
Familial Resemblance for Serum Metabolite Concentrations
Draisma et al., 2013
Twin Res Hum Genet 2013, 16 (5), 948–961.
View abstract
Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms
Yet et al., 2016
View abstract
Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2
Diabetes: A Mendelian Randomisation Analysis
Lotta et al., 2016
PLOS Medicine
View abstract
Genetics of human metabolism: an update
Kastenmüller et al., 2015
View abstract
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite
levels
Draisma et al., 2015
View abstract
Identification of putative biomarkers for type 2 diabetes using metabolomics in the Korea Association REsource
(KARE) cohort
Lee et al., 2016
View abstract
Interrogating causal pathways linking genetic variants, small molecule metabolites and circulating lipids
Shin et al., 2014
View abstract
Metabolic profiles of male meat eaters, fish eaters, vegetarians, and vegans from the EPIC-Oxford cohort
Schmidt et al., 2015
View abstract
Metabolomics in epidemiology: sources of variability in metabolite measurements and implications
Sampson et al., 2013
View abstract
Metabolomics platforms for genome wide association studies—linking the genome to the metabolome
Adamski & Suhre, 2013
Curr. Opin. Biotechnol. 2013, 24 (1), 39–47.
View abstract
Network based conditional genome wide association analysis of human metabolomics
Tsepilov et al., 2016
bioRxiv
View abstract
Novel Genetic Associations with Serum Level Metabolites Identified by Phenotype Set Enrichment Analyses
Ried et al., 2014
View abstract
Plasma concentrations and intakes of amino acids in male meat-eaters, fish-eaters, vegetarians and vegans: a
cross-sectional analysis in the EPIC-Oxford cohort
Schmidt et al., 2015
View abstract
Profiles of amino acids and biogenic amines in the plasma ofCri-du-Chat patients
Furtado et al., 2017
Journal of PHarmaceutical and Biomedical Analysis
View abstract
Random Survival Forest in practice: a method for modelling complex metabolomics data in time to event
analysis
Dietrich et al., 2016
View abstract
Reliability of Serum Metabolites over a Two-Year Period: A Targeted Metabolomic Approach in Fasting and
Non-Fasting Samples from EPIC
Carayol et al., 2015
View abstract
Short-term NO 2 exposure is associated with long-chain fatty acids in prospective cohorts from Augsburg,
Germany: results from an analysis of 138 metabolites and three exposures
Ward-Caviness et al., 2016
View abstract
The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection
Willemsen et al., 2013
View abstract
The human plasma-metabolome: Reference values in 800 French healthy volunteers; impact of cholesterol,
gender and age
Trabado et al., 2017
PLOS One
View abstract
The UK Adult Twin Registry (TwinsUK Resource)
Moayyeri et al., 2013
View abstract
Topographical Body Fat Distribution Links to Amino Acid and Lipid Metabolism in Healthy Non-Obese Women
Martin et al., 2013
PLoS ONE 2013, 8 (9), e73445.
View abstract
GASTROENTEROLOGY
Characterization of Selected Metabolic and Immunologic Markers Following Exclusive Enteral Nutrition of
Pediatric Crohn’s Disease Patients
Brahmbhatt et al., 2016
View abstract
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial
McIntosh et al., 2016
View abstract
Fumonisins affect the intestinal microbial homeostasis in broiler chickens, predisposing to necrotic enteritis
Antonissen et al., 2015
Veterinary research 46
View abstract
High Fat Diet Accelerates Pathogenesis of Murine Crohn’s Disease-Like Ileitis Independently of Obesity
Gruber et al., 2013
PLoS ONE 2013, 8 (8), e71661.
View abstract
Metabolic alterations in children with environmental enteric dysfunction
Semba et al., 2016
View abstract
Metabolomics for Biomarker Discovery in Gastroenterological Cancer
Nishiumi et al., 2014
View abstract
Metabonomics Reveals Metabolite Changes in Biliary Atresia Infants.
Zhou et al., 2015
View abstract
GYNAECOLOGY & FERTILITY
A metabolomics approach to characterize phenotypes of metabolic transition from late pregnancy to early
lactation in dairy cows
Kenéz et al., 2016
View abstract
A Postnatal Diet Containing Phospholipids, Processed to Yield Large, Phospholipid-Coated Lipid Droplets,
Affects Specific Cognitive Behaviors in Healthy Male Mice
Schipper et al., 2016
View abstract
A Predictive Metabolic Signature for the Transition from Gestational Diabetes to Type 2 Diabetes
Allalou et al., 2016
View abstract
Alterations of the Lipid Metabolome in Dairy Cows Experiencing Excessive Lipolysis Early Postpartum
Humer et al., 2016
View abstract
Altered levels of acylcarnitines, phosphatidylcholines, and sphingomyelins in peritoneal fluid from ovarian
endometriosis patients
Vouk et al., 2016
View abstract
Altered Theca and Cumulus Oocyte Complex Gene Expression, Follicular Arrest and Reduced Fertility in Cows
with Dominant Follicle Follicular Fluid Androgen Excess
Summers et al., 2014
View abstract
Endometriosis is associated with aberrant metabolite profiles in plasma
Letsiou et al., 2017
Fertility and Sterility
View abstract
Hormone Modelling in Preterm Neonates: Establishment of Pituitary and Steroid Hormone Reference Intervals.
Greaves, R. F., et al., 2015
View abstract
Identification of predictive biomarkers of disease state in transition dairy cows
Hailemariam et al., 2014
View abstract
Imbalanced lipid homeostasis in the conditional Dicer1 knockout mouse epididymis causes instability of the
sperm membrane
Björkgren et al., 2014
View abstract
Impact of a western diet on the ovarian and serum metabolome
Dhungana et al., 2016
View abstract
Lactation is associated with altered metabolomic signatures in women with gestational diabetes
Much et al., 2016
View abstract
LC-MS/MS improves screening towards 21-hydroxylase deficiency.
Ambroziak, et al., 2014
View abstract
Maternal cytokine status may prime the metabolic profile and increase risk for obesity in children
Englich et al., 2017
International Journal of Obesity
View abstract
Maternal Early Pregnancy Serum Metabolomics Profile and Abnormal Vaginal Bleeding as Predictors of
Placental Abruption: A Prospective Study
Gelaye et al., 2016
View abstract
Maternal PCaaC38:6 is Associated With Preterm Birth - a Risk Factor for Early and Late Adverse Outcome of
the Offspring
Li et al., 2016
View abstract
Metabolic Profiles during an Oral Glucose Tolerance Test in Pregnant Women with and without Gestational
Diabetes
Lehmann et al., 2015
View abstract
Metabolomic prediction of fetal congenital heart defect in the first trimester
Bahado-Singh et al., 2014
View abstract
Metabolomics reveals differences in postprandial responses to breads and fasting metabolic characteristics
associated with postprandial insulin demand in postmenopausal women
Moazzami et al., 2014
View abstract
Metabolomics reveals effects of maternal smoking on endogenous metabolites from lipid metabolism in cord
blood of newborns
Rolle-Kampczyk et al., 2016
View abstract
Metabotypes with properly functioning mitochondria and anti-inflammation predict extended productive life span
in dairy cows
Huber et al., 2016
View abstract
Non-invasive prediction of embryo developmental potential by embryo culture medium quantitative secretomic
Camillo et al., 2015
View abstract
Perinatal Asphyxia: A Review from a Metabolomics Perspective
Fattuoni et al., 2015
View abstract
Persistently Altered Metabolic Phenotype following Perinatal Excitotoxic Brain Injury
Blaise et al., 2017
Developmental Neuroscience
View abstract
Postpartum outcomes in women with gestational diabetes and their offspring: POGO study design and first-year
results
Hummel et al., 2013
View abstract
Sildenafil Therapy Normalizes the Aberrant Metabolomic Profile in the Comt(-/-) Mouse Model of
Preeclampsia/Fetal Growth Restriction
Stanley et al., 2015
View abstract
Total testosterone to dihydrotestosterone ratio assessed by LC-MS/MS predicts a worse metabolic profile not
only in PCOS patients
Ambroziak et al., 2017
Ginekologika Polska
View abstract
INFLAMMATION & IMMUNOLOGY
A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses
Köberlin et al., 2015
View abstract
Absence of PD-L1 on tumor cells is associated with reduced MHC I expression and PD-L1 expression increases
in recurrent serous ovarian cancer
Aust et al., 2017
Scientific Reports
View abstract
Activation of the Serotonin Pathway is Associated with Poor Outcome in COPD Exacerbation: Results of a Long-
Term Cohort Study
Meier , 2017
Lung
View abstract
Activation of the tryptophan/serotonin pathway is associated with severity and predicts outcomes in pneumonia:
results of a long-term cohort study
Meier et al., 2017
Clinical Chemistry and Laboratory Medicine
View abstract
Activation of the tryptophan/serotonin pathway is associated with severity and predicts outcomes in pneumonia:
results of a long-term cohort study
Meier et al., 2016
Clin Chem Lab Med
View abstract
Admission levels of asymmetric and symmetric dimethylarginine predict longterm outcome in patients with
communityacquired pneumonia
Voegeli et al., 2017
View abstract
Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy
Ruiz et al., 2015
View abstract
Application of 'omics technologies to biomarker discovery in inflammatory lung diseases
Wheelock et al., 2013
View abstract
Biomarker candidates for the detection of an infectious etiology of febrile neutropenia
Richter et al., 2015
View abstract
Characterization of metabolomic signatures in septic shock patients: a data mining approach
Cambiaghi, 2017
PhD Thesis
View abstract
Classification of osteoarthritis phenotypes by metabolomics analysis
Zhang et al., 2014
View abstract
Combined Proteome and Eicosanoid Profiling Approach for Revealing Implications of Human Fibroblasts in
Chronic Inflammation
Tahir et al., 2017
View abstract
Comprehensive proteomic and metabolomic signatures of nontypeable Haemophilus influenzae-induced acute
otitis media reveal bacterial aerobic respiration in an immunosuppressed environment
Harrison et al., 2015
View abstract
Extensive alterations of blood metabolites in pediatric cerebral malaria
Gupta et al., 2017
PLOS One
View abstract
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial
McIntosh et al., 2016
View abstract
Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers
Ward-Caviness et al., 2017
Heart
View abstract
Increased efficacy of omalizumab in atopic dermatitis patients with wild-type filaggrin status and higher serum
levels of phosphatidylcholines
Hotze et al., 2014
View abstract
Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma
Ried JS. et al., 2013
Allergy 2013, 68 (5), 629–636.
View abstract
Intravenous Fish Oil and Pediatric Intestinal Failure–Associated Liver Disease: Changes in Plasma Phytosterols,
Cytokines, and Bile Acids and Erythrocyte Fatty Acids
Calkins et al., 2017
Journal of Enteral and Parenteral Nutrition
View abstract
Investigating the Role of Sphingolipids in Innate Immunity
Koeberlin, 2015
PhD Thesis
Metabolomic Profiling in Individuals with a Failing Kidney Allograft
Bassi et al., 2017
PLOS One
View abstract
Microdialysis Sampling from Wound Fluids Enables Quantitative Assessment of Cytokines, Proteins, and
Metabolites Reveals Bone Defect-Specific Molecular Profiles
Förster et al., 2016
View abstract
Mortality prediction in patients with severe septic shock: a pilot study using a target metabolomics approach
Ferrario et al., 2016
View abstract
Multi-omics analysis of serum samples demonstrates reprogramming of organ functions via systemic calcium
mobilization and platelet activation in metastatic melanoma
Muqaku et al., 2016
View abstract
Physical exercise induces specific adaptations resulting in reduced organ injury and mortality during severe
polymicrobial sepsis
Sossdorf et al., 2013
Crit. Care Med. 2013, 41 (10), e246-55.
View abstract
Plasma Metabolomics Biosignature According to HIV Stage of Infection, Pace of Disease Progression, Viremia
Level and Immunological Response to Treatment
Scarpelini et al., 2016
PLOS One
View abstract
Proteomics and Metabolomics for In Situ Monitoring of Wound Healing
Kalkhof et al., 2014
View abstract
Recovery of pan-genotypic and genotype-specific amino acid alterations in chronic hepatitis C after viral
clearance: transition at the crossroad of metabolism and immunity
Chang et al., 2017
Amino Acids
View abstract
Relationship between the lipidome, inflammatory markers and insulin resistance
Wallace et al., 2014
View abstract
Relationship between the quantity of oral Candida and immunological vigor
Hayashi et al., 2016
View abstract
Serum lipid alterations identified in chronic hepatitis B, hepatitis B virus-associated cirrhosis and carcinoma
patients
Wu et al., Scientific Reports 2017
Scientific Reports
View abstract
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
Markle et al., 2013
Science 2013, 339 (6123), 1084–1088.
View abstract
Steroid concentrations in atopic dermatitis patients: Reduced plasma DHEAS and increased cortisone levels.
Mihály et al., 2014
View abstract
Urinary Metabolomics for Noninvasive Detection of Borderline and Acute T Cell-Mediated Rejection in Children
After Kidney Transplantation
Blydt-Hansen et al., 2014
View abstract
MICROBIOME
Improved Glucose Homeostasis in Obese Mice Treated with Resveratrol is Associated with Alterations in the
Gut Microbiome
Sung et al., 2016
Diabetes
View abstract
Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota
Geurts et al., 2015
View abstract
Effects of Surgical and Dietary Weight Loss Therapy for Obesity on Gut Microbiota Composition and Nutrient
Absorption
Antje, 2014
View abstract
Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested
casecontrol study
Fedirko et al., 2017
BMC Medicine
View abstract
Fecal metabolome of the Hadza hunter-gatherers: a host-microbiome integrative view
Turroni et al., 2016
View abstract
Fumonisins affect the intestinal microbial homeostasis in broiler chickens, predisposing to necrotic enteritis
Antonissen et al., 2015
Veterinary research 46
View abstract
Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells
Belcheva et al., 2014
View abstract
Impaired Bile Acid Homeostasis in Children with Severe Acute Malnutrition
Zhang et al., 2016
View abstract
Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E−/− mice
Ryan et al., 2017
Microbiome
View abstract
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
Markle et al., 2013
Science 2013, 339 (6123), 1084–1088.
View abstract
PULMONOLOGY
Activation of the Serotonin Pathway is Associated with Poor Outcome in COPD Exacerbation: Results of a Long-
Term Cohort Study
Meier , 2017
Lung
View abstract
Activation of the tryptophan/serotonin pathway is associated with severity and predicts outcomes in pneumonia:
results of a long-term cohort study
Meier et al., 2017
Clinical Chemistry and Laboratory Medicine
View abstract
Activation of the tryptophan/serotonin pathway is associated with severity and predicts outcomes in pneumonia:
results of a long-term cohort study
Meier et al., 2016
Clin Chem Lab Med
View abstract
Admission levels of asymmetric and symmetric dimethylarginine predict longterm outcome in patients with
communityacquired pneumonia
Voegeli et al., 2017
View abstract
Constant-load exercise decreases the serum concentration of myeloperoxidase in healthy smokers and smokers
with COPD
Holz et al., 2015
View abstract
Endogenous metabolites and inflammasome activity in early childhood and links to respiratory diseases
Herberth et al., 2015
View abstract
Metabolomics screening identifies reduced L-carnitine to be associated with progressive emphysema
Conlon et al., 2015
View abstract
TECHNOLOGY
Alterations in Human Liver Metabolome during Prolonged Cryostorage
Abuja et al., 2015
View abstract
Assessing unintended effects of a mammary-specific transgene at the whole animal level in host and non-target
animals
Clark et al., 2014
View abstract
Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of
metabolite profiles
Dharuri et al., 2013
BMC Genomics 2013, 14, 865.
View abstract
Comparison of 7 Published LC-MS/MS Methods for the Simultaneous Measurement of Testosterone,
Androstenedione, and Dehydroepiandrosterone in Serum
Buttler et al., 2015
View abstract
Comprehensive Metabolomic and Lipidomic Profiling of Human Kidney Tissue: A Platform Comparison
Leuthold et al., 2017
Computational Tools for the Secondary Analysis of Metabolomics Experiments
Booth et al., 2013
Comput Struct Biotechnol J 2013, 4, e201301003.
View abstract
Data standards can boost metabolomics research, and if there is a will, there is a way
Rocca-Serra et al., 2016
View abstract
Differential cellular metabolite alterations in HaCaT cells caused by exposure to the aryl hydrocarbon receptor-
binding polycyclic aromatic hydrocarbons chrysene, benzo[a]pyrene and dibenzo[a,l]pyrene
Potratz et al., 2016
View abstract
Embedding metabolism into the omics landscape: Integrated analysis of metabolomics, transcriptomics and
proteomics data from cellular to organ level
Bartel, 2016
View abstract
Embedding standards in metabolomics: the Metabolomics Society data standards task group
Salek et al., 2015
View abstract
Epigenetics meets metabolomics: An epigenome-wide association study with blood serum metabolic traits
Petersen et al., 2013
View abstract
Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical
strategy for measuring human steroid perturbations
Jeanneret et al., 2015
View abstract
Hormone Modelling in Preterm Neonates: Establishment of Pituitary and Steroid Hormone Reference Intervals.
Greaves, R. F., et al., 2015
View abstract
Identification and MS-assisted interpretation of genetically influences NMR signals in human plasma
Raffler et al., 2013
Genome Med 2013, 5 (2), 13.
View abstract
Integrating metabolomics profiling measurements across multiple biobanks
Dane et al., 2014
View abstract
Interlaboratory Reproducibility of a Targeted Metabolomics Platform for Analysis of Human Serum and Plasma
Siskos et al., 2016
Analytical Chemistry
View abstract
Liquid chromatography-high resolution mass spectrometry-based cell metabolomics
Hounoum et al., 2015
View abstract
Metabolic signatures of esophageal cancer: NMR-based metabolomics and UHPLC-based focused
metabolomics of blood serum
Zhang et al., 2013
View abstract
Metabolome analyses in exposome studies: Profiling methods for a vast chemical space
Athersuch, 2016
View abstract
Metabolomics and the Diagnosis of Human Diseases - A guide to the markers and pathophysiological Pathways
Affected
Medina et al., 2014
View abstract
Metabolomics–Young Field, Bright Future
Dutton, 2013
View abstract
Mid- and long-term correlations of plasma metabolite concentrations measured by a targeted metabolomics
approach
Kühn et al., 2016
View abstract
Multiplexed steroid profiling of gluco- and mineralocorticoids pathways using a liquid chromatography tandem
mass spectrometry method
Travers et al., 2016
View abstract
Non-Additive Effects of Genes in Human Metabolomics
Tsepilov et al., 2015
View abstract
Optimizing Urine Processing Protocols for Protein and Metabolite Detection
Siddiqui et al., 2015
View abstract
Plasma and serum metabolite association networks: comparability within and between studies using NMR and
MS profiling
Suarez-Adam et al., 2017
Journal of Proteome Research
View abstract
Pre-analytical sample quality: metabolite ratios as an intrinsic marker for prolonged room temperature exposure
of serum samples
Anton et al., 2015
View abstract
Quo vadis? The challenges of recombinant protein folding and secretion in Pichia pastoris
Puxbaum et al., 2015
View abstract
Random Survival Forest in practice: a method for modelling complex metabolomics data in time to event
analysis
Dietrich et al., 2016
View abstract
Removing the bottlenecks of cell culture metabolomics: fast normalization procedure, correlation of metabolites
to cell number, and impact of the cell harvesting method
Muschet et al., 2016
View abstract
Simultaneous quantification of 17-hydroxyprogesterone, androstenedione, testosterone and cortisol in human
serum by LC-MS/MS using TurboFlow online sample extraction
Gervasoni et al., 2016
View abstract
Targeted metabolomics identifies reliable and stable metabolites in human serum and plasma samples
Breier et al., 2014
View abstract
The Bovine Ruminal Fluid Metabolome
Saleem et al., 2013
View abstract
The effect of haemolysis on the metabolomic profile of umbilical cord blood
Denihan et al., 2015
View abstract
The human plasma-metabolome: Reference values in 800 French healthy volunteers; impact of cholesterol,
gender and age
Trabado et al., 2017
PLOS One
View abstract
The human saliva metabolome
Dame et al., 2015
View abstract
The Human Urine Metabolome
Bouatra et al., 2013
View abstract
Towards merging untargeted and targeted methods in mass spectrometry-based metabolomics and lipidomics
Cajka and Fiehn 2015
View abstract