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Graduate course in Carbohydrate Chemistry Carbohydrates – Biological relevance

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Page 1: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Carbohydrates –Biological relevance

Page 2: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Page 3: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Blood group antigens (ABH)

Page 4: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Carbohydrate antigens

Page 5: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Receptors for bacteria and toxins

Page 6: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Cell wall of Gram-negative bacterium

Page 7: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

LPS,O-antigen

Page 8: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Lipid A

Lipid A

Page 9: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Peptidoglucan

O

OO

OH

OHNHAc

O

NHAc

HO

O

HNPeptide

H

Page 10: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Cellulose - plants

O

OO

OH

OHOH

HO

OH

HO

COOH

HO

H3CO

Ferulic acid – cross linking

Page 11: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Chitin

O

OO

OH

OHNHAc

HO

NHAc

HO

Page 12: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Antibiotics

Page 13: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Glycoproteins

Page 14: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Protein folding and sorting

Page 15: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Heparin

Page 16: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Proteoglycan

Page 17: Carbohydrates – Biological relevance · Carbohydrate Chemistry Cellulose - plants O O O OH OH OH HO OH HO COOH HO H3CO ... disaccharides provides the H type I and H type 2 Irisaecharides

Graduate course inCarbohydrate Chemistry

Saponin