Canadian Life Sciences Trend Analysis 2014

About Us

The following statistical information has been obtained from Biotechgate. Biotechgate is a global, comprehensive, Life Sciences database encompassing the Biotechnology, Pharmaceutical and Medical Device industries. www.biotechgate.com

The Canadian Life Sciences Database is a part of the global Biotechgate and is brought to you in partnership with BIOTECanada, HTX and Life Sciences Ontario. www.canadianlifesciences.com

Biotechgate is owned and operated by Venture Valuation AG, a Zurich based company specializing in independent assessment and valuation of technology-driven companies in high growth industries, such as the Life Sciences (Biotech, Pharma, Medtech), ICT, high-tech, Nanotech, Cleantech and Renewable energy. www.venturevaluation.com

Overview of the Canadian Life-science industry

2014 Statistics

Biotech - Therapeutics 145

Biotech - Other 228

R&D Services 200

Medtech companies 374

Supplier & Engineering Companies 931

Other Life Sciences Companies 1296

Percentage of Publicly Owned Companies 11%

Venture Capital Raised (2013) USD 165.3m

Venture Capital Raised (2012) USD 81.9m

Number of Technologies 180

Licensing Opportunities 146

Number of Employees

Company Ownership

Company Foundation Timeline – MedTech and Supplier / Engineering Sectors

Key Activities of Medical Technology Companies

Key Activities of Supplier / Engineering Companies

Overview of the Canadian Biotech Industry

2014 Statistics

Total Biotech Companies 573

Biotech - Therapeutics 145

R&D Services 200

Biotech - Other 228

Number of Initial Public offerings (2013) 1

Percentage of Publicly Owned Companies 11%

Venture Capital Raised (2013) USD 139m

Venture Capital Raised (2012) USD 72m

Licensing Opportunities (Biotech – Therapeutics) 123

Company Foundation Timeline – Biotech Sector

Key Activities of Biotechnology Companies

Key Activities of Bio (R&D) Companies

The Canadian Pipeline –Breakdown by Stage of Development

Biotech Products by Indication

Venture Biotech Financing in Canada - Half-yearly Data

Major Financing Rounds (H2 2013 – H1 2014)

Company Sector USD M

Boreal Genomics R&D Services 18

enGene Inc. Therapeutics & Diagnostics 13.3

Zymeworks Inc. Therapeutics & Diagnostics 12

Highland Therapeutics

Therapeutics & Diagnostics 6.7

Calevia Inc. Therapeutics & Diagnostics 4

About Biotechgate

Biotechgate contains over 30’000 high quality company profiles which include company descriptions, contact information, product pipeline information, financing rounds and management details. Profiles are regularly updated by the companies themselves, as well as by an experienced database team, to ensure the accuracy and relevance of the data.

To register for free or learn more about the different subscription options, please visit www.biotechgate.com.

Terms of Use

The “Canadian Life Sciences Trend Analysis” is based on data entered in the Biotechgate Database available at www.biotechgate.com. The statistics and graphs in this presentation are based on figures and information entered in this database and we do not guarantee any accuracy hereof.

The use of the figures and graphs provided in this report is free of charge for any presentations as long as www.biotechgate.com is clearly cited as the source. For all other uses please contact us for terms and conditions.

Biotechgatec/o Venture Valuation VV AGKasernenstrasse 11 +41 (43) 321 86 608004 Zurich info@venturevaluation.comSwitzerland www.venturevaluation.com