by taylor kudirka. calcitonin is a hormone known to participate in calcium and phosphorus...
TRANSCRIPT
![Page 1: By Taylor Kudirka. Calcitonin is a hormone known to participate in calcium and phosphorus metabolism. In mammals calcitonin is the C cells in the](https://reader036.vdocuments.mx/reader036/viewer/2022062422/56649f2c5503460f94c4717c/html5/thumbnails/1.jpg)
By Taylor Kudirka
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Calcitonin is a hormone known to participate in calcium and phosphorus metabolism.
In mammals calcitonin is the C cells in the thyroid gland.
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Calcitonin was first purified in 1962 by Chopp and Cheney.
At first they believed it was a secretion of the parathyroid glands and was later identified as the secretion of the C-cells of the thyroid gland.
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This hormone participates in calcium and phosphorous metabolism.
Calcitonin counteracts the parathyroid gland.
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1. Inhibits calcium absorption by the intestines.
2. Inhibits osteoclast activity in bones.
3. Inhibits renal tubular cell reabsorption of calcium allowing it to be secreted into the urine.
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Calcitonin is a polypeptide hormone of 32 amino acids.
It weights about 3454.93 daltons.
Its structure comprises a single alpha helix.
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Calcitonin can be used as a tumor maker for medullary thyroid cancer.
It can also be used on biopsy samples to establish whether they are metastasis of the original cancer.
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Calcitonin is secreted from the thyroid glands
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Calcitonin is very important for women because it helps protect against calcium loss during pregnancy and lactation.
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The End