bruker news · bruker news innovation with integrity ... • cutting-edge innovations: ... • 2016...
TRANSCRIPT
![Page 1: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/1.jpg)
Bruker News
Innovation with Integrity
Eric Leonardis
Regional Sales Manager Western&Southern Europe
Bruker BioSpin, France
BeNeLux Users Meeting
Brussels, November 25th, 2016
![Page 2: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/2.jpg)
Magnetic Resonance
At the Heart of our Company
• Committed to serve the MR community
• Continue to invest heavily in innovation with ~10% annual R&D investment
• Provide scientists with
• Cutting-edge innovations: e.g. GHz NMR technology, DNP-NMR
• Highest performance NMR, EPR, DNP, preclinical MRI instruments
• Drug discovery & development p plus QC tools for Biopharma
• High-value analytical solutions for Applied, Industrial & Clinical Markets: e.g. NMR FoodScreener, Avance™ IVDr, Minispec TD-NMR
• First-class global support and service, & after-market services: LabScape™
Innovation with Integrity
![Page 3: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/3.jpg)
Bruker Announces René Lenggenhager as
BioSpin Group President
Innovation with Integrity
• Appointment of Dr. René Lenggenhager as President of the Bruker BioSpin Group, effective November 1st, 2015
• Since 2004, Dr. Lenggenhager has served as General Manager for Laboratory Weighing at METTLER TOLEDO (MTD).
• Very successful track record in sustainable, profitable growth with a focus on customers and innovation
Dr. René Lenggenhager combines academic and scientific qualification with international management skills.
![Page 4: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/4.jpg)
Innovation with Integrity
• Inauguration of a new Prize to be awarded in an annual fashion at the European Magnetic Resonance (EUROMAR) conference
• Awarded to recognize recent beneficial applications of Magnetic Resonance going beyond fundamental research
• 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio Frydman, Robert Griffin, Wiktor Kozminski, Vladimir Sklenar, and Thomas Vosegaard
The Richard R. Ernst Prize in Magnetic Resonance
![Page 5: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/5.jpg)
The Evolution of Magnetic Resonance
Productivity and Throughput
Bigger and Better New Applications
Innovation in
Magnetic
Resonance
Innovation with Integrity
![Page 6: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/6.jpg)
Innovation with Integrity
• Active shielding reduces space requirements by > one order of magnitude
• Aeon 1 GHz magnets leverage advanced BEST superconductors
• Active refrigeration eliminates LN2, reduces LHe boil-off essentially to zero
New GHz-class magnet, novel CryoProbes, 111 kHz MAS probes, and
new NMR methods expand frontiers in structural biology, membrane protein and intrinsically disordered protein (IDP) research
World's first shielded Aeon 1 GHz installed
Aeon 1 GHz at Research Center for Bio-Macromolecules at University of Bayreuth
![Page 7: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/7.jpg)
Solid-State DNP Spectrometer Gyrotron and Klystron Options
Work in Progress: 263 GHz Klystron
• Offer a lower-price more compact
microwave source at 263 GHz
• Design compatible with possible upgrade later to gyrotron for full power performance
• Power output ~ 5W
• Available 2017
DNP with Gyrotron
DNP with Klystron
(EIK)
![Page 8: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/8.jpg)
Triple-Resonance 111kHz MAS 1GHz Probe Fully protonated 15N,13C Proteorhodopsin
Innovation with Integrity
Courtesy: Guido Pintacuda,
Daniela Lalli, ENS Lyon
![Page 9: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/9.jpg)
Pharma: Shorter time-to-market
Drug Discovery
• New TS tools facilitate FBS data analysis
• Complete workflow: samplePro Tube, sampleJet, QCI/TCI, CMC_q & TS FBS tools!
Process Understanding and Optimisation
• Growing InsightMR family with InsightXpress & InsightEPR
• InsightXpress greatly streamlines Rxn optimisation, monitors decay t1/2=1s!
QC – Potency by qNMR
• One single experiment determines the amount of active ingredient in a drug
• Rapid, selective, reliable method that frees the expert from routine testing!
QC – Quantification of Components in Solid Mixtures
• Rapid, push-button, bench top: The minispect mq20 + Dynamics Center
• Quantifies components based on their t1 saturation recovery curve
![Page 10: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/10.jpg)
Researcher sees this:
High Field ‘Benchtop’ NMR: Lab2NMR
The details:
![Page 11: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/11.jpg)
Honey Profiling and updated Wine
Modules of the NMR FoodScreener™
• Authentication, fraud detection and labeling compliance enable brand protection, guarantee quality and protect investment and reputation of merchants
• Quickly gaining acceptance by global food analysis labs and honey-packers
• Stand-alone application modules further enhance ROI of our Food Screeners™
– Fam. Michaud Apiculteurs, MELI® first honey-packers to adopt novel NMR solution
– Wine module now includes extended coverage of regions in France, Italy and Spain
• Laboratory at Bruker for food authenticity and quality determination granted ISO/IEC 17025 accreditation
Innovation with Integrity
![Page 12: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/12.jpg)
Preclinical Imaging Innovations New 3T Preclinical MRI System with Superior Cryogen-free Magnet and PET/MRI Option
• Novel, superior liquid cryogen-
free 3 Tesla magnet
• No liquid Helium or Nitrogen
filling required
• Magnet stays at field up to
4 hours during power or cold
water failure
• Upgradable to PET/MRI
Innovation with Integrity
![Page 13: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/13.jpg)
LabScape™
Service and Life Cycle for Support Magnetic
Resonance & Preclinical Imaging
• New, flexible approach to life-cycle management, maintenance and service
• Maintenance, repair and upgrade agreements for NMR, EPR, MRI and other preclinical imaging product lines
• Reliable, optimal instrument performance
• Access to up-to-date expertise from trained engineers and applications scientists
More at bruker.com/LabScape
Innovation with Integrity
![Page 14: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/14.jpg)
AVANCE Console Generations & Support
• AVANCE D*X: end of production 2000
• AVANCE I: end of production 2004
• AVANCE II: end of production 2006
• AVANCE III: end of production 2012
• AVANCE III HD: in production (since 2012)
![Page 15: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/15.jpg)
AVANCE Console Generations & Support AVANCE II
• AVANCE II:
• 2016: 10 years end of production
• End of Service (EOS) January 2018, support on best effort at reasonable endeavour basis
![Page 16: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/16.jpg)
www.TheResonance.com: A new look to a very successful site!
www.TheResonance.com
Innovation with Integrity
![Page 17: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/17.jpg)
Announcement:
Free TopSpin™ Processing
www.bruker.com/FreeTopSpin
Innovation with Integrity
Download your free version today!
![Page 18: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/18.jpg)
Sales and Service organization in Benelux Bruker BioSpin
Leiderdorp
Brussels
Sales
• Sales Manager : Marc Penders
• Sales engineer : Chu Sun Wong
Application/Training
• Henny Janssen
Service
• Michel Gilles (BE)
• Adri Schipper (NL)
• Henri van Etten (NL)
• Bert Van Zijl (NL)
Back-office in Brussels and Leiderdorp
![Page 19: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/19.jpg)
Welcome to our Guest Speaker!
Innovation with Integrity
Dr. Alex De Groot
Janssen Pharmaceutica
Q2C-NMR: a new way of using NMR
![Page 20: Bruker News · Bruker News Innovation with Integrity ... • Cutting-edge innovations: ... • 2016 Ernst Prize committee: Profs. Lucia Banci (chair), Marina Bennati, Lucio](https://reader038.vdocuments.mx/reader038/viewer/2022103107/5ada53c97f8b9a86378d3a6d/html5/thumbnails/20.jpg)
© Copyright Bruker Corporation. All rights reserved.
Innovation with Integrity
Copyright © 2011 Bruker Corporation. All rights reserved. www.bruker.com Innovation with Integrity