brain neoplasm. benign –may have aggressive tendencies –may transition to more aggressive lesion...

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Brain Neoplasm

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Page 1: Brain Neoplasm. Benign –May have aggressive tendencies –May transition to more aggressive lesion –Tends to be slower growing Primary malignant –Age distribution

Brain Neoplasm

Page 2: Brain Neoplasm. Benign –May have aggressive tendencies –May transition to more aggressive lesion –Tends to be slower growing Primary malignant –Age distribution

Brain Neoplasm• Benign

– May have aggressive tendencies– May transition to more aggressive lesion– Tends to be slower growing

• Primary malignant– Age distribution for various tumors– Impact due to mass effect or invasion

• Metastatic – History of pre-existing neoplasm– May be primary presentation

• Brain MRI modality of choice

Page 3: Brain Neoplasm. Benign –May have aggressive tendencies –May transition to more aggressive lesion –Tends to be slower growing Primary malignant –Age distribution

Astrocytoma

• Irregular low attenuation lesion (CT)

• Isodense to gray matter central area

• Relatively ‘low grade’

• Surrounding edema (black)

Page 4: Brain Neoplasm. Benign –May have aggressive tendencies –May transition to more aggressive lesion –Tends to be slower growing Primary malignant –Age distribution

Astrocytoma• MRI• Parietal lesion• White

representing surrounding edema on T2 images

• Contrast enhancement on T1+C

T2 T2

T1 T1+C

Page 5: Brain Neoplasm. Benign –May have aggressive tendencies –May transition to more aggressive lesion –Tends to be slower growing Primary malignant –Age distribution

Meningioma• Medial posterior

mass adjacent to the meninges

• Slow growing• Minimal mass

effect• Intense

enhancement

T1+C T1+C

T1T2

Page 6: Brain Neoplasm. Benign –May have aggressive tendencies –May transition to more aggressive lesion –Tends to be slower growing Primary malignant –Age distribution

Meningioma• Extra-axial lesion• Impact based on mass effect• May be quite large without symptoms

Page 7: Brain Neoplasm. Benign –May have aggressive tendencies –May transition to more aggressive lesion –Tends to be slower growing Primary malignant –Age distribution

Cystic Astrocytoma

• Cystic mass in posterior fossa• Rim and mural nodule enhancement on

contrast – far right image at arrows

Page 8: Brain Neoplasm. Benign –May have aggressive tendencies –May transition to more aggressive lesion –Tends to be slower growing Primary malignant –Age distribution

Metastatic Brain Tumor

• Multiple ring enhancing lesions

• Brain edema (white rim T2)

• Known lung cancer

T2

PD

T1

T1+C

Page 9: Brain Neoplasm. Benign –May have aggressive tendencies –May transition to more aggressive lesion –Tends to be slower growing Primary malignant –Age distribution

Lung Neoplasm

• Nodule upper right lung field

• Patient with brain metastases