b.pharmacy-2 scm.examinations (re.) endterm …..._ 1 rollno. b.pharmacy - 2nd semester...

21
B.Pharmacy-2nd Scm. Examinations (RE.) Pharmaceutical Management; 01260205 End Term Theory Examinations Time: 03:00hrs. Max. Marks: 75 Instructions: I. Writeyour Roll no.on the Questionpaper. . . . 2. Candidate should ensure that they have been provided with the correct question paper. Complaints In IllISregards, If any, should be made within 15minutesof the commencementof the exam.No eomplaint(s) will be entertained thereafter. 2:._Dra~~ Dia~~~mw~~reve.::.r_re_q._u_ir_ed_.~ __ -r-r--r-' _ PART-I Attempt All questions: 1) Cheque Is a type of Negotiable instruments (True / False) 2) Forecast and PlannIng Is the fundamental element of Management (True / False) 3) Expa'ndthe term CFA ~ : . (lx20=20) 4) ABC analysis is based on alphabetical arrangement in inventory control (True /False) 5) Define Delegation of Authority 6) Define Salesmanship 7} 'Define Sales promotion 8) Consumer buy products and customer use products ( True / False) 9) Selling emphasizes on the Product and Marketing emphasizes on customer need (True /False) 10) One is to one is a feature of indirect marketing (True / False) 11) Tele marking is a part of direct marketing (True / False) 12) Buy it Now is a type of personal selling (True /False) 13} Define Entrepreneur 14) Define Pharmacoeconomics 15) Trade of values between two parties isTransaction or Competition. (select one) 16) Selling of Medicines are a type of Direct Marketing (True /False) 17) 'Feature tells and benefits sells is a correct statement '(True /False) 18) FMCG stands for ~ : . 19) We need a drug license to sell Milk products and infant meal (true / False) 20) Generic medicines are those products whose patent has been expired ( True / False)

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Page 1: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

B.Pharmacy-2nd Scm. Examinations (RE.)Pharmaceutical Management; 01260205

End Term Theory ExaminationsTime: 03:00hrs. Max. Marks: 75Instructions:I. Write your Roll no. on the Question paper. . . .2. Candidate should ensure that they have been provided with the correct question paper. Complaints In IllISregards, If any,

should be made within 15minutesof the commencementof the exam.No eomplaint(s) will be entertained thereafter.2:._Dra~~ Dia~~~mw~~reve.::.r_re_q._u_ir_ed_.~__ -r-r--r-' _

PART-IAttempt All questions:

1) Cheque Is a type of Negotiable instruments (True / False)

2) Forecast and PlannIng Is the fundamental element of Management (True / False)

3) Expa'ndthe term CFA ~ : .

(lx20=20)

4) ABC analysis is based on alphabetical arrangement in inventory control (True /False)

5) Define Delegation of Authority

6) Define Salesmanship

7} 'Define Sales promotion

8) Consumer buy products and customer use products ( True / False)

9) Selling emphasizes on the Product and Marketing emphasizes on customer need (True

/False)

10) One is to one is a feature of indirect marketing (True / False)

11) Tele marking is a part of direct marketing (True / False)

12) Buy it Now is a type of personal selling (True /False)

13} Define Entrepreneur

14) Define Pharmacoeconomics

15) Trade of values between two parties is Transaction or Competition. (select one)

16) Selling of Medicines are a type of Direct Marketing (True /False)

17) 'Feature tells and benefits sells is a correct statement '(True /False)

18) FMCG stands for ~ : .

19) We need a drug license to sell Milk products and infant meal (true / False)

20) Generic medicines are those products whose patent has been expired ( True / False)

Page 2: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

-2-

PART-II •

Note: - Attempt any two questions. (10 X 2=20)

1. Write in detail about various Inventory control methods for Medicines. Explainvarious

functions of Material Management Department.

2. What do you understand by Motivation, explainits character istics?DiscussNonmonetary

Motivational theories.

3. Differentiate between Marketing and Selling.Explainvarious methods of Pharmaceutical

selling. Discussin detail about the functions of Medical Representative in Pharmaceutical

Selling.

4. What do you understand by Human ResourcePlanningand procedure of Recruitment and

training? Explainthe various characteristics of career planning after completing BPharmacy. \....

PART-III

Note: - Attempt any seven questions. (5 X 7=35)

1. ExplainPrinciplesof Communication and its importance

2. Write a short note on International Marketing.

3. Describe various Conceptsof Management

4. Write short note on Evaluation of material management systems

5. Write short note on Pharmaceutical Advertising.

6. Write brief note on Principles of Accountancy

7. Write short note on Market Researchand Market Share

8. Explainvarious channelsof Distribution of Pharmaceuticals

9. Write short note on Product mix and Product life cycle

10. Write about various prescribing habits of Physician

11. Define Cashbook, Promissory Note and trail balance

12. Discusslaws of demand and supply

Page 3: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

_ 1

Roll No.

B.PHARMACY - 2nd SEMESTERENVIRONMENTAL SCIENCE - 1260219END TERM THEORY EXAMINATION

Time: 3 Hrs Max. Marks: 50Instructions:I. Write Roll No. on the Question Paper.2. Candidate should ensure that they have been provided with correct question paper. Complaint(s) in this regard, if

any, should be made within 15 minutes of the commencement ofthe exam. No complaint ill this regard will beentertained thereafter.

3. Draw diagram wherever required.-------------------------------------------------

PART-I

Long Answer Type Questions (Attempt Any Two) (2xlO=20)

Q.1. What is Environment?Why there is need for publicAwareness and why it is a multidisciplinarysubject?

Q.2. Define pollution.Brieflydescribethe sources, effects and controllingtechniques of Air pollution?Q.3. What is Ecological Succession?Briefly explain the different stagesof the ecological succession process

with suitable example?

PART-IIShort Answer type questions (attempt any six) (6x5=30)

Q.4. What are ecological pyramids? Explain different types of ecological pyramids with diagram?Q.5. What is homeostasis? Explain feedback mechanisms with suitable example?Q.6. Explain the harmful effects of modern agriculture on environment?Q.7. What do you mean by (a) eutrophication (b) water logging (c) Reforestation?Q.8. How can you as an individual conserve different natural resources?Q.9. Differentiate between London smog and photochemical smog?Q.IO. What are the major sources of soil pollution? How docs soil pollution affects soil productivity?Q.l1. Write short notes on:

(a) Bio-magnification(b) Energy Flow models(c) Nitrogen Cycle

**************ETE MAY2018***************

Page 4: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

Roll No.

B. PHARMACY- 2NDSEMESTERCOMPUTER APPLICATIONS IN PHARMACY-01260214

END TERM THEORY EXAMINATION

Time: 03:00 Hrs Max. Marks: 50Instructions:1. Write Roll No. on the Question Paper.2. Candidate should ensure that they have been provided with correct question paper. Complaint(s) in this regard, if

any, should be made within 15 minutes of the commencement of the exam. No complaint in this regard will beentertai ned thereafter.

3. Each part is compulsory. Marks are indicated against each question.4. Draw diagram wherever required.

PART -I

Long Answer Type Questions (Answer ANY TWO of three) :- (2xlO=20)

Q.1. (a) Convert (89)10to binary number and (10 111)2 to decimal number.(b) What is web server? Explain its different types.

Q.2. Explain HPLC and GC with suitable diagrams.

Q.3. (a) What is Lab diagnostic system? Explain the role of computer In medical labtechnology.

(b) What is biological database? Explain its types.

PART-II

Short Answer Type Questions: (Answer ANY SIX of eight) :- (6x5=30)

Q.1. Explain various tools of information gathering.

Q.2. Explain process life cycle with suitable diagram.

Q.3. Define E-prescribing refills. Explain the technical components of E-prescription.

Q.4. What is LIMS? Write its functionalities.

Q.5. Solve following: (i) (lOll)r(lOlO)2 (ii) (0101)2-(1001)2, using 2's complement.

Q.6. What is the database in MS Access? Explain its types.

Q.7. Explain any three applications of computer in pharmacy.

Q.8. What are the different fields in which bio-informatics is being used? Explain the role of

internet in bio-informatics.

************ETE MAY-JUNE 2018*****************

Page 5: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

B.Pharmacy-2nd Sem. Examinations (RE.)Pharmaceutics-II (General Pharmacy); 01260201

End Term Theory ExaminationsMax. Marks: 75

-;:--~--;-;----------------------------------Instructions:1. Write your Roll no. on the Question paper.2. Candidate should ensure that they have been provided with the correct question paper. Complaints in this regards. If any.

should be made within IS minutes of the commencement of the exam. No complaint(s) will be entertained thereafter.3. Draw Diagram wherever required.

Time: 03:00hrs.

Part I Objective type questions: Total 20 Marks

Q.l Define the following terms (1 mark each)

)

i) Proof Spiritii) Cachetsiii) Snuffsiv) Tablet trichurates.v) Dusting powdervi) Write the name of suspending agentsvii) Deflocculated of suspensionsviii) Phase inversion of emulsionix) Surfactants with examples

Q.2 Single response Questionsi) Effervescent powder usually contains:

a) Sodium bicarbonateb) Citric Acid

(1 mark each)

c) Tartaric acidd) All of the above

ii) The rate of sedimentation of a flocculated suspension is:a) Low c) Highh) Controlled d}l Jnknown

iii) HLB relates toa) Hydrophobic Lipophillic balanceb) Hydrophillie Lipophobic balancec) Hydrophillic Lipophillic balanced) All of the Above

iv)Which of the following compounds is a natural emulsifying agent?a) Acaciab) Polysorbate 80

c) Lactosed) Sodium monopalmitate

v) Ointment can be prepared by:

a) Trituration method c) Fusion methodb) Chemical Reaction d) All of the above

Q.3 Fill in the blanks (1 mark each)i) Isotonic solution for eye is equivalent to % of sodium chlorideii) Melting range oftheobroma oil is ·.····························,

Page 6: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

iii) Pessaries are suppositories meant for administration into the ..iv) paper is best for protecting a divided hygroscopic powder.v) Lanolin is an example of ··· .vi) Macrogol ointment BP is an example of. , , , .

Part II: Long assay tYpe questions: (Answer any two of four)Marks: (2x10= 20)

Q.1 What are ointments? Classify different ointment bases used in the preparations of ointments.

Q.2 Define emulsions. Describe in detail about the types of emulsions, method of preparati on '-"

and pharmaceutical applications of emulsions.\

Q.3 Write in detail about the formulation aspects of Suppositories, its bases and applications of'

suppositories.QA Describe in detail about suspension, types of suspension, preparation methods and stability

of suspension.

Part III: Short answer type questions: (Answer any seven of ten)Marks: 7X5= 35

Q: 1Write a short note on insuffiations with examples.

Q: 2 Explain about the isotonic solutions.

Q: 3 Write a note on displacement value.Q: 4 Enumerate about the Effervescent powders with examples.

Q: 5 Write a note on identification tests of emulsions.

Q: 6 Discuss about the significance of infusion process.Q: 7 What are Emulsifying agents? Give the classification of emulsifying agents.

Q: 8 Write a brief note on percolation process with applications

Q: 9 Explain about dentifrices with examples.

Q: 10Write in detail about the applications of jellies.

Page 7: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

Roll No.

B.PHARMACY - 2NDSEMESTERHUMAN ANATOMY & PHYSIOLOGY-II, 01260210)

END TERM THEORY EXAMINATION

Time: 03:00 Hrs Max. Marks: 75Instructions:1. Write Roll No. on the Question Paper.2. Candidate should ensure that they have been provided with correct question paper. Complaint(s) in this regard, if any,

should be made within 15 minutes of the commencement of the exam. No complaint in this regard will be entertainedthereafter.

3. Marks are indicated against each question.4. Draw diagram wherever required.

PART-I

Q.1. MDLTIPLE CHOICE QUESTIONS:-a) Somatic nervous system is composed of

1. Motor neurons 2. Sensory neurons 3. Relay neuronsb) Which of the following cavities contain a component ofCNS?

1. Abdominal 2. Cranial 3. Thoracicc) Which of the following are structural features of trachea?

1. C-shaped cartilage 2. Smooth muscle fibres 3. ciliad) Which hormone exerts greatest influence on metabolism?

1. Thyroxine 2. Insulin 3. Cortisone

(lxS)

e) Basal metabolic rate ofa child is than an old person.1. Higher 2. Lower 3. Same

Q.2. Fill in the blanks :-a) The system enables movement, supports the body & protects internal

(lx5)

organs.b) Parietal cells secrete -----c) The amount of air that cannot be expelled is called _d) Sperms are activated & nourished through gland.e) Loss of appetite is called _

Q.3. State whether the given statement is True or False:- (lx5)a) The spinal cord is continuous with medulla oblongata of the brain.b) Villi are present in Pancreas.c) Basal Metabolic Rate (BMR) measures time elapse between eating & passing stool.d) Emphysema is characterized by destruction of walls of alveoli producing abnormally

large spaces.e) During the Secretary phase of Menstruation, the lining of uterus rebuilds.

Q.4. Match the following: (lxS)1. Cerebrum2. Lipase3. Alveoli4. Sperm5. Uracil

a. Fatsb. Gas Exchangec. Guanild. Parietal lobee. Sertoli cells

Page 8: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

PART- II

Long Answer type Questions (Attempt any two of the following): (2xlO=20)Q.1. Enlist the various organs of respiration. With the help of diagram discuss the mechanism of

respiration.Q.2. Explain in detail the mechanism of urine formation by kidneys.Q.3. Discuss in detail the structure & function of anterior pituitary.

PART- III

Short Answer type Questions (Attempt any seven of the following):Q.l. With the help of diagram discuss the structure of meninges of brain.Q.2. Discuss the structure & functions of Fore Brain.Q.3. Discuss the location, structure & physiology of liver.

\ Q.4. Discuss the various phases of gastric juice secretion.Q.S. Write short note on resustication methods.Q.6. Discuss the anatomy & physiology of kidney.Q.7. Explain the physiological regulation of electrolyte balance by RAAS.Q.8. Write short note on Spermatogenesis.Q.9. Enlist the various organs of Female Reproductive System & discuss Uterus in brief.Q.IO. Differentiate between Diabetes Mellitus & Diabetes Inspidus.

(7xS=3C

\.-/

"

Page 9: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

Roll No.

B.PHARMACY - 2NDSEMESTER (Re-appear)PHARMACEUTICAL CHEMISTRY-II (ORGANIC CHEMISTRY-I)

[SUBJECT CODE: 01260202]END TERM THEORY EXAMINATION

Time: 03:00 Hrs Max. Marks: 75Instructions:I. WriteRollNo. on the Question Paper.2. Candidateshould ensure that they have been providedwith correct question paper. Complaint(s) in this regard, if

any, should be made within 15minutes of the commencementof the exam.No complaint in this regard will beentertainedthereafter.

3. Marksare indicatedagainst each question.4. Drawdiagramwherever required.

PART-IOBJECTIVE TYPE QUESTIONS (ALL QUESTIONS COMPULSORY) (1X20=20)

(1*4=4).. Q.l. Define the following:­a) Hybridizationc) Diastereoisomers

Q.2. State True/ Falsea) Two carbons atoms joined by a double bond(C=C) can rotate freely.b) Chiral centre is an atom bonded to four different atoms or groups.c) Acetylene is the simplest alkyne.d) Acid chlorides are derivatives of carboxylic acids.

Q.3. Fill in the blanksa) Hybridization of C atom in alkane is .b) General formula for olefins is .

b) Chiralityd) Conformational isomers

(1*4=4)True/FalseTrue/FalseTrue/FalseTrue/False

(1*4=4)

c) Separation of a racemic mixture into its dextro and leavo components is termed as .d) Isomers in which the similar groups lie on the same side is called as isomers.

Q.4. Match the following:- (1*4=4)a) 2-aminoethanol i) CH3CH2CH=C(CH3)CH20Hb) 2-methyl-2-penten-l-ol ii) CH3CH(OH) CH2CH2COOHc) Ethyl methyl acetylene iii) H2NCH2CH20Hd) 4- hydroxy pentanoic acid iv) C2HsCCCH3

Q.5. Single response questionsa) In propyne there are :-I. 6 sigma bond & 2 pi bond3. 6 sigma bond & 1 pi bond

(1*4=4)

2. 7 sigma bond & 1 pi bond4. 8 sigma bond

b) 2-butanol is optically active because it contains :-I. Chiral carbon 2. Plane of symmetry3. Hydroxyl group 4. Center of symmetryc) Optical isomers that are not mirror images are calledI. Diastereomers3. Metamers

2. Enantiomers4. Meso compound

P.T.O.

Page 10: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

d) Keto-enol tautomerism is shown by1. Benzaldehyde3. Acetone

2. Benzophenone4. Acetic acid

PART-IISHORT ANSWER TYPE QUESTIONS (Answer any 7 out of 10) (7*5 =35)

Q.1. Explain Bayer strain theory.Q.2. Define and classify isomerism with examples.Q.3. Write a note on acid-base concepts.Q.4. Define and differentiate between atomic and molecular orbitals.Q.5. Why aldehydes are more reactive than ketones in nucleophilic addition reaction?Q.6. Write a note on free radical and diel's -alder reaction of dienes.Q.7. Explain specification of configuration.Q.8. Write a note on derivatives of carboxylic acidQ.9. Give the methods of preparation of alkyl halides.

\ Q.I0. Explain bonding and anti bonding orbitals by giving at least two examples.

PART -IIILONG ANSWER TYPE QUESTIONS (Answer any 2 out of 4) (2x10=20)

Q.1. Explain the chemical properties of alkyl halides with mechanism.Q.2. Write a note on (any four) :-

a. Carbocationb. Carbene

d. Carbanione. Nitrene

Q.3.Q.4.

c. Nitrenium ionExplain the chemical properties of aldehydes and ketones with mechanism.Give the methods of preparation of (any two):-a. A Ikanes c. Alkenesb. Alkynes d. Cycloalkanes

\.-/

Page 11: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

RoIINo.

B.PHARMACY - 2NO SEMESTER[SUBJECT NAME: -PHARMACEUTICAL ORGANIC CHEMISTRY-I]

[SUBJECT CODE: 01260211]END TERM THEORY EXAMINATION (MAY-JUNE 2018)

Time:03:00 Hrs Max. Marks:75

Instructions:I. Write Roll No. on the Question Paper.2. Candidate should ensure that they have been provided with correct question paper. Complaint(s) in this regard, if

any, should-be made within 15 minutes of the commencement of the exam. No complaint in this regard will be

entertained thereafter.3. Part -I is compulsory. Marks are indicated against each question.4. Draw diagram wherever required.

PART-lOBJECTIVE TYPE QUESTIONS ( ALL QUESTIONS COMPULSORY)

'" Q.1. Define the following:-

(1*20=20)(1 *4=4)

a) Inductive effectc) Electrophile

Q.2. State True/ Falsea) Hydrogen bond donor solvent is aprotic solvent.b) Removal of -H and -x from adjacent carbons is a ~-elimination.c) 9 sigma bonds are present in CH2=CH-CH=CH2d) Tollen's reagent with acetic acid produce silver mirror.

Q.3. Fill in the blanksa) Hybridization of C atom in ethene is .b) Carbylamines test is given by amine.c) Electron withdrawing substituents (CI, Br,CN) , the acidity.d) Correct name of 4,4,3-trimethyl-I-hexyne is ·.

Q.4. Match the following:-

b) Electromeric effectd) Nucleophile

(1 *4=4)True/FalseTrue/FalseTrue/FalseTrue/False

(1 *4=4)

(1 *4=4)

a) 2-aminoethanolb) 2-methyl-2-penten-I-olc) Ethyl methyl acetylened) 4- hydroxy pentanoic acid

i) CH3CH2CH=C(CH3)CH20Hii) CH}CH(OH) CH2CH2COOHiii) H2NCH2CHzOHiv) C2H5CCCH3

Q.5. Single response questionsa) Which of the following aldehyde used alone will undergo an aldol condensation'?I. Formaldehyde 2. Butanal3. Benzaldehyde 4. 2-propenalb) Which combination of chemicals is known as the" lucas reagent"?I. NaCI,HCI,CuCh 2. HCI,ZnCb

(1 *4=4)

3. HCI,SnCb 4. NaCI,SnCbc) Which nucleophile is required to convert 1- bromo butane to butyl methyl ether'?1. Ethoxide ion 2. Methoxide ion3. Butoxide ion 4. Hydroxide ion

P.T.O.

Page 12: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

d) What product results from the reaction of acetyl chloride and methylamine. followed byLiAIH4 and H20 ?

I. CH3CH2NHCH2CH3 2. (CH]CH2)N

PART-II

SHORT ANSWER TYPE QUESTIONS (Answer any 7 out of 10)

Q.l.Q.2.

Q.3.Q.4.Q.5.Q.6.

\ Q.7.Q.8.Q.9.Q.I0.

(7*5 =35)

Write a note on acidity of carboxylic acid and effect of substituent on it.Explain electrophilic addition and free radical addition reaction of conjugated dieneswith mechanism.Why are aldehydes more reactive than ketone in nucleophilic addition reaction?How will you distinguish among 1°,2° and 3° alcohols?Explain the hybridization of alkanes and alkenes by giving two examples of each.With example differentiate between satyzeff's rule, markownikoff's rule and anti­rnarkownikoff's rule.Explain EI and E2 reaction with mechanism and kinetics.Classify organic compounds with examples.Give the methods of preparation of amines.Explain the chemical properties of alkanes

PART -IllLONG ANSWER TYPE QUESTIONS (Answer any 2 out of 4) ( 2*10=20)

Q.1. Explain and differentiate between SN I and SN2. Write the factors affecting S", I and S,,2reaction along with examples.

Q.2. Write a note on (any four) :-

Q.3.Q.4.

a. Aldol condensationb. Cross aldol condensation

d. Crossed cannizaro reactione. Benzoin condensation

c. Cannizaro reactionWrite a note on chemical properties of alkyl halides along with reaction mechanism.Give the uses and structure of the following :-a. Vanillinb. Methyl salicylate

f. Benzaldehyde

c.d.e.

AmphetamineTetrach loroethylenePropylene glycol

g.h.

Benzyl benzoate

I.

Acetyl salicylic acidChloral hydrateSuccinic acidJ.

Page 13: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

Roll No.

B. PHARMACY i~DSEMESTERSUBJECT NAME & CODE: - BIOCHEMISTRY-1260212

END TERM THEORY EXAMINATION

Time: 3:00 Hrs Max. Marks: 75Instructions:I. Write Roll No. on the Question Paper.2. Candidate should ensure that they have been provided with correct question paper. Complaint(s) in this regard. if

any, should be made within 15 minutes of the commencement of the exam. No complaint in this regard will beentertained thereafter.

3. Parts of a question should be attempted in sequential order. Marks are indicated against each question.4. Draw diagram wherever required.

PART - A (OBJECTIVE TYPE QUESTIONS OMR SHEETS)

Q.1.\

Name The Outermost Boundary Of Cella) Plasma membrane b) cytoplasm

(1)c) nuclear membrane d) none of the above

Q.2. Name the process in which the passage of water goes from a region of higherconcentration to lower concentration through a semi permeable membrane (1)a) Osmosis b) Diffusion c) Both d) None of the above

Q.3. Which enzyme protect DNA from ageinga) DNA polymerase b) Topoisomerase

(1)c)Deoxyribonuclease d) Telomerase

Q.4. All are involved in synthesis of DNA except (1)a) DNA polymerase b) Topoisomeras c) Reverse transcriptase d) Deoxyribonuclease

Q.5. Which of the co-enzymes do not take part in citric acid cyclea) NAD b) PLP c) FAD

(1)d)TPP

Q.6. DNA replication Required all Except (1)a) Elongation factor b) Deoxynucleotide phosphate c) DNA polymerase d) RNA primer

Q.7. Succinyl co-enzyme is formed fromall the following except (1)a) Aspartic acid b) isoleucine c) valine d) odd chain fatty acid

Q.8. Co-enzyme area) Non protein molecule

c) Structural analog of enzyme

(1)b) colloidal protein molecule

d) Different form of same enzyme

Page 14: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

Q.9. A-I,4 linkage are hydrolyze bya) Lactose b) sucrose

(1)c) maltose d) isomerase

Q.I0. Which of the intermediates listed in a dicarboxylate hydroxyl acida) Succinate b) Fumarate c) malate d) oxaloacetate

(1)

Q.l1. Citric acid cycle is regulated by the availability ofa) ATP b) Glucose c) tatty acid d) Succinate dehydrogenase

(1)

Q.12. Which enzyme catalyses and irreversible reactiona) Transketolase b) Phosphofructokinase

(I)

c) Aldolase d) Glyceraldehyde 3- phosphate dehydrogenase

Q.13. Enzymes which are synthesized in active form called asa) Co-enzyme b) proenzyme c) holoenzyme

~

(I)d) lysoenzyrne

Q.14. Glycogen synthesis is activated bya) Insulin b) protein kinase c) adrenalin

(1)d) ATP

,Q.15. Name an organelle which serves as a primary packaging are for molecule that will bedistributed throughout the cell (I)a) Mitochondria b) plastids c) Golgi apparatus D) Ribosomes

Q.16. Which among the following sentence is not correct about the organelles (1)a) They are found in all eukaryotic cells b) They are found in multi cellular organismsc) They coordinate to produce the cell d) They are small sixed and mostly internal

Q.17. All the following test are positive for lactose excepta) Benedict b) Barfoed c) Molisch

~(1)

d) Osazone

Q.18. Glucose can have isomer due to presence of 4 asymmetric carbon atom.a) 18 b) 16 c) 20 d)24

(1)

Q.19. .. forms glucose is stored in plantsa) dextin b) fat c) starch

(I)d) Glycogen

Q.20. Non reducing disaccharide is ..a) Maltose . b) fructose c) starch (I)

d) Sucrose

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PART-B

Long assay type questions (Answer Any TWO) (2XIO=20)

Q1. What is glycolysis? With the aid ofa flow chart show the reactions ofthe glycolysis,

giving energetic under the aerobic and anaerobic conditions?

Q2. Give an account of f3- oxidation of palmitic acid and its energetics?

Q3. By means of a flow chart show the biosynthesis of purine nucleotides?

Q4. Discuss the steps of the kreb's cycle and its energetics?

PART-C

\ Short answer type questions (Answer any SEVEN) (7x5 =35)

Q1. Describe the mechanism of enzyme action and various factors affecting enzyme

activity?

Q2. Give the components of respiratory chain showing the sites of ATP formation

Q3. Write a short note on HMP Pathway with its importance?

Q4. What is biornolecules? Classify them with examples?

Q5. Write Short note on Glycogen storage diseases.

Q6. Explain the steps involved in RNA Synthesis.

Q7. Give an account of biosynthesis of cholesterol.

Q8. What are ketone bodies? How they are formed and utilized?

Q9. Explain in detail various applications of enzymes?

QI0. Give the biological significance of nucleic acids. Give the difference between RNA and

DNA.

Page 16: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

Roll No.

B. Pharmacy 2nd Semester (Reappear)PHARMACOLOGY-II (Human Anatomy & Physiology-II), 01260203

END TERM THEORY EXAMINATIONTime: 03:00 Hrs Max. Marks: 75Instructions:I. Write Roll No. on the Question Paper.2. Candidate should ensure that they have been provided with correct question paper. Complaint(s) in this regard, if

any, should be made within 15 minutes of the commencement of the exam. No complaint in this regard will beentertained thereafter.

3. Draw diagram wherever required.

PART-lI Multiple Choice Questions (lX5=5)

Q1. Which of the following is not the effector of ANS(a) Skeletal Muscle (b) Cardiac Muscle (c) Smooth Muscle

Q2. Enzyme formed in mouth is known as(a) Starch (b) Lipase (c) Amylase

Q3. Optic nerve is the functional part of(a) Nose (b) Eye (c) Ear

Q4. Which substance should not be expected in urine normally(a) Nitrogenous waste (b) Sodium (c) Protein

Q5. Which of the following Hormone pairs is not produced by same endocrine gland(a) FSH/LH (b) ACTH/ADH (c) Prolactin IGH

II Fill in the Blanks (lX5 = 5)

1. fluid acts as water cushion to support the brain &spinal cord2. The moist ball made up of chewed up food & saliva is called _3. bulb contains olfactory receptors for smell4. Urea is a waste product that results from the metabolism of _5. The (hormone) causes the breast to increase the synthesis of milk.

III State whether the given statement is either True or False1. The lO'" cranial nerve is also called the Vagus Nerve2. The most fat digesting enzymes are produced in small intestine3. Production of sweat by s~eat glands is voluntary in nature4. Renin release from Adrenal Cortex will cause DCT to reabsorb more Sodium ions5. ADH is inhibited by Alcohol

(lX 5 = 5)

Page 17: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

IV Match the followingI. Meninges2. Amylase3. Macula lutea4. Major Calyx5. Gastrin

(lX5 = 5),

a. Peptide Hormoneb. Nephronc. Eyed. Starche. Duramater

PART-2

Short Answer type questions (Attempt any SEVEN of the following) (7x5 = 35)

Q1. What are Cranial Nerves? Enlist its various names

Q2. Describe the structure & function of Brain Stem

Q3. Discuss the structure & function of Salivary Glands & add a note Saliva

Q4. Discuss the histology of Stomach with a neat labeled diagram

Q5. With the help of a well labeled diagram discuss the structure & function of Skin

Q6. Describe the three regions of Pharynx & their functions

Q7. Discuss the anatomy & physiology of Human Eye

Q8. Differentiate between Diabetes Mellitus & Diabetes lnspidus

Q9. Write a brief note of Menstrual Cycle

QIO. Write short note on Protein Synthesis

Ql1. Discuss the anatornyec physiology of Testis with neat labeled diagram

PART-3

Long Answer type questions (Attempt any TWO of the following) (lOX2=20)

Q1. What is a Neuron? Discuss its structure & function. Discuss in detail about the

neurohumoral transmission at neuronal synapse

Q2. Draw a well labeled diagram of nephron. Discuss the physiology of urine

formation in detail

Q3. With neat labeled diagram discuss the structure & function of small intestine

*************ETE MAY 2018****************

Page 18: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

Roll No.

B.PHARMACY 2NDSEMESTER (Reappear)(SUBJECT NAME & CODE:-PHARMACEUTICAL

MICROBIOLOGY - 01260204)END TERM THEORY EXMINATION

Time: 03:00 Hrs Max. Marks: 75Instructions:l. Write RollNo. on the Question Paper.2. Candidate should ensure that they have been providedwith correct question paper. Complaint(s) in this regard, if

any, should be made within 15minutes of the commencementof the exam.No complaint in this regardwill beentertained thereafter.

3. Parts of a question should be attempted in sequentialorder.Marks are indicated against each question.4. Draw diagramwherever required.

PART - A (OBJECTIVE TYPE QUESTIONS) (1X20=20)

Q.1. Bacteria having no flagella are unable toa) Move b) reproduce c) stick to tissue surface d) grow in nutrient agar

(1)

Q.2. Genetic system is located in the prokaryotes ina) Nucleoid b) chromatin c) nuclear material d) all of these

(1)

Q.3. Gram staining was introduced bya) Christian gram b) Alfred gram

(1)c) Robertcook d) Louis pasteur

Q.4. Mycoplasms , rickettsiae & chlamydiae area) Types offungi b) bacteria c) protozoa

(1)d) viruses

Q.5. Enzymes are:a)organic compounds b) inorganic compounds c) organic & inorganic both d) All

(1)

Q.6. For most bacteria the optimum pH for growth lies betweena) 6.5-7.5 b) 3.5-4.5 c) 4.5-5.5

(1)d) 5.5-6.5

Q.7. Identify the term that can describe a disinfectant that inhibits the growth of fungi (1)a)fungicidal b)fungisepsis c)fungistatic d)fungigenic

Q.8. The term that describes an environment completely free of microbes is (1)a) Antibiotic b) Aspectic c) Antisepsis d) Antigen

Q.9. Temperature used for hot air oven is (1)a) 100° for I hour b)1200for I hour c) 1600for lhour d)600for 1hour

Q.I0. To produce Penicillin, main fermentable source in culture is (1)a) Glucose b) Lactose c) sulphate d) minerals

Q.ll. Cobalt containing vitamin is (1)a) B12 b) B6 c) B2 d) Bi

Page 19: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

Q.12. A hypothesis becomes a 'theory' when it has been proven by an experiment. True/False (1)

Q.13. In his studies on fermentation, Louis Pasteur presented the first evidence that somemicroorganisms could grow an aerobically. True/ False (1)

Q.14. Incubation temperature range used for the growth of bacteria in a sterility test as per I.P is (1)a) 20-25°C b) 25-30°C c) 30-35° C d) 35-40°C

Q.15. Streptomycin antibiotic is produced by (1)

Q.16. Viruses are surrounded by a protective coat called (1)

Q.17. Match the following:-1. Dry heat sterilization2. Moist heat sterilization3. Gas sterilization4. Liquid sterilization

(4X1=4)i) Hydrogen peroxide sterilizerii) Formaldehyde sterilizeriii) Autoclaveiv) Hot air oven

PART - B (LONG ANSWERS)

Attempt any two questions of the following(10X2=20)

\ Q.1. Differentiate between the following :-(a) Prokaryotes & Eukaryotes(b) Gram positive & Gram negative bacteria

Q.2. Differentiate between the following :-(a) Viruses & bacteria(b) Spores & Capsules

Q.3. Explain in detail construction and working of laminar air flow.Q.4. Discuss the microbiological assay of vitamin B 12.

PART - C (SHORT ANSWERS)

Attempt any seven of the following:(7X5=35)

Q.1. Draw a well labeled diagram of bacterial cell. Explain flagella.

Q.2. Write a note on Electron microscope.

Q.3. Define the terms sterilization, disinfectant, antiseptics & sanitation.

Q.4. Explain the Pharmaceutical significance of fungi.

Q.5. Define staining. Explain gram staining technique.

Q.6. Explain LAL test.Q.7. Explain salient feature of enzyme immobilization

Q.8. Give salient features of a fermenter with a labeled diagram.

Q.9. Draw a layout of commercial production of Streptomycin.

Q.I0. Briefly outline the contribution of Louis Pasteur in the history of Microbiology.

*****ETE MAY 2018******

Page 20: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

Roll No.

B. PHARMACY _2nd SEMESTERPATHOPHYSIOLOGY - 1260213

END TERM THEORY EXAMINATION

Time: 03:00 Hrs Max. Marks: 75Instructions:I. Write Roll No. on the Question Paper.-, Candidate should ensure that they have been provided with correct question paper. Complaint(s) in this regard, if

any, should be made within 15 minutes of the commencement of the exam. No complaint in this regard will beentertai ned thereafter.

3. Each part is compulsory. Marks are indicated against each question.4. Draw diagram wherever required.

PART - IObjective Type Questions:Q.l. Define the following terms:­

a) Hyperplasia" b) Metaplasia

c) Dysplasiad) Homeostasisc) Hypertrophy

.Q.2. Single Response Questions:-a) Which of the following is not a cause of peptic ulcer

1) Helicobacter pylori2) Use of ACE inhibitors drugs3) Gastrin hormone4) Uses ofNSAID drugs

b) Which of the following disease is not Sexually Transmitted Disease1) Meningitis2) AIDS3) Syphilis4) Gonorrhea

c) Disease in which cholesterol and fatty material accumulate in wall of arteries1) Diabetes2) Tuberculosis3) Arteriosclerosis4) Atherosclerosis

d) Etiological factor for type 2 diabetes mellitus include1) Genetic2) Insulin resistance3) Being overweight and inactivity4) All of them

e) Iodine deficiency diet which cause a hyperplasia of thyroid gland1) Goiter2) Cretinism3) Tetany4) Addison disease

(lx20=20)(lx5=5)

(lx5=5)

Page 21: B.Pharmacy-2 Scm.Examinations (RE.) EndTerm …..._ 1 RollNo. B.PHARMACY - 2nd SEMESTER ENVIRONMENTAL SCIENCE -1260219 END TERM THEORY EXAMINATION Time: 3Hrs Max. Marks: 50 Instructions:

Q.3. State whether True/False:-a) Asthma is caused by alcoholb) z Excess salt can cause hypertensionsc) Alzheimer disease are associated with deficiency of dopamined) Life span of RBC is 120 dayse) Folic acid therapy can cause sickle cell anemia

Q.4. Match the followinga) TB Excess saltb) Peptic ulcer Uric acidc) Hepatitis Mycobacteriumd) Gout H.pylori

(h5V'5)

(lx5=5)

e) Hypertension Virus

PART-IILong Answer Type Questions (Answer any two of fuur):-Q.1. What is Diabetes "explain in detail about its pathophysiologyQ.2. Describes pathophysiology of ACLIteand Chronic renal failureQ.3. Write the pathophysiology and symptoms of AsthmaQ.4. Write only pathophysiology of following

ParkinsonAthersclerosis

(2XIO='__'

PART -IIIShort Answer Type Questions: (Answer any seven of ten):­Q.1. Write the etiopathogenesis of EpilepsyQ.2. Discuss the process of wound heal ingQ.3. Write a note on Peptic ulcerQ.4. Explain iron deficiency Anemia and Megaloblastic anemiaQ.5. Elaborate the Hypertension causes and symptomsQ.6. Descri be till' d isordcr of Thyroid glandQ.7. Discuss the pathology ofTubcrculusisQ.8. Write a note on Rheumatoid ArthrirtisQ.9. Discuss in brief about Cancer and its classificationQ.I0. Discuss the etiology and symptoms of Sexually Transmitted Disease

(7x5=35)

************ETE MAY 2018*****************