botany lecture 1 [compatibility mode]
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Department of PharmacognosyDepartment of PharmacognosyProf . Dr. Nahla Ayou b Prof . Dr. Nahla Ayou b
Lecture ( Lectu re (1 1) )
Semester TwoSemester Two 20142014
BotanyBotanyand Medicinal Plantsand Medicinal Plants
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Objectives of the course Objectives of the course
To enable the student to:
Acquire knowledge about the modern concept andscope of medicinal plants.
Identify various types of plant cells and cell contents.
Have general information on cultivation, collectionand processing of medicinal plants
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Describe the morphology and anatomy of different plant organs (leaves, barks & flowers), &Identify the drugs both in entire or powderedforms .
now t e active constituents o me icina p antsand identify the major groups by chemical test.
Know the biological effects of the activeconstituents.
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Trease& Evans' Pharmacognosy by William Charles
Botany :An introduction to Plant Biology, Thirdedition by James D. Mauseth, 2008.
Evans, 2002.
Fundamentals of Pharmacognosy and Phytotherapy
by Michael Heinrich, Joanne Barnes, Simon Gibbons,and Elizabeth M.Williamson, 2004.
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http://www.hort.purdue.edu/newcrop/med aro/default.html
http://www.herbmed.org/
http://www.danish schnapps recipes.com/plants.html
http://www.botanical.com/
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Pharmakon Drug
What is meant by Pharmacognosy?
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Gnosis to acquire knowledge
(( The entire knowledge of drugs) )
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PharmacognosyPharmacognosy
-Pharmacognosy is one of the important branches of pharmacy.-It deals with the study of structural, physical,chemical and sensory characters of crude drugs of plant, animal,marine or mineral origin and includestheir history, cultivation, collection, storage and use.- Aims for the search of new drugs from naturalsources.
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1- Identificationof the source of
drug.
2- Determination of the morphological
characters
Scope of Scope of
3- knowledge aboutcultivation, collectionand preparation.
4- Testing theactive
constituents5-Investigation of
its potency andpurity
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A flowering plant
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Crude Drug: Natural product:
A medicinally useful
drug of plant or animal
origin in its raw or
A natural product is a
chemical compound or
substance produced by a
natural form without
any further processing
or modification.
living organism , found in
nature and usually has a
pharmacological activit for
use in pharmaceutical drug
discovery and drug design.11
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Examples of Crude DrugsExamples of Crude Drugs
Entire plants or animals :
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CochinealCrimson colored dye
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Examples of Crude Drugs (cont.)Examples of Crude Drugs (cont.)
Entire organs of plants or animals:
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SennaClove
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Examples of Crude Drugs (cont.)Examples of Crude Drugs (cont.)
Minerals: chalk, kaolin, talc.
Substances derived from plants beeswax,
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Official & Unofficial Drugs:
Official Drug :
A drug listed and described in the book by
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government as the legal authority for standards
Pharmacop ia.
Others > Unofficial
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The history of pharmacy was for centuries identical with the historyof Pharmacognosy.
minerals, animals and fungi.
Medicinal uses.
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EgyptiansEgyptians ((EbersEbers papyruspapyrus,, 15501550 BC)BC)
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DioscoridesDioscorides ((4040--8080 AD)AD) was a Greek was a Greek physician, pharmacologist and botanist.physician, pharmacologist and botanist.((encyclopedia about herbal medicineencyclopedia about herbal medicine that was widelythat was widelyread for more thanread for more than 11,,500500 years.years. ))DeDe MateriaMateria MedicaMedica ((600600 medicinal plants)medicinal plants)
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The Islamic eraThe Islamic eraIbnIbn AlAl--TabariTabari ((850850 AD)AD)
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Ibn SIbn S nn ((980980 10371037 ))Canon of MedicineCanon of Medicine
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IbnIbn AlbitarAlbitar ((11481148--11971197))
Jame Jame--alal--MuffradatMuffradat
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Modern AgeModern Age The main shift in herbal medicine came,The main shift in herbal medicine came,
when it became clear in the earlywhen it became clear in the early 19 19 thth
century that pharmaceutical properties of century that pharmaceutical properties of plants are due to specific moleculesplants are due to specific moleculescompoun s t at can e so ate ancompoun s t at can e so ate an
characterized.characterized. This led to the development of a field of This led to the development of a field of research now called natural productresearch now called natural productchemistrychemistry i.ei.e .. Phytochemistry andPhytochemistry andPhytotherapyPhytotherapy
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Origin of the Crude Drug
I- Biological III- Commercial
Botanical zoological
II-Geographical
It includes the scientific name of the plant producing theIt includes the scientific name of the plant producing thedrug and it is very important to avoid any variation of thedrug and it is very important to avoid any variation of thedrudru 27
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II-- Biological OriginBiological OriginBinomial systemBinomial system
-- It is the nomenclature of the drugs, developedIt is the nomenclature of the drugs, developed
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by by LinnausLinnaus (Swedish scientist).(Swedish scientist).
--Deals withDeals with twotwo successive namessuccessive names((GenusGenus andand speciesspecies ).).
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Each plant is termed by two words or partsEach plant is termed by two words or parts
enus or generic nameenus or generic nameGG pecies or specific namepecies or specific namess
It begins always withIt begins always with
with awith arCapital letteCapital lette
followed byfollowed bysmall lettersmall letterthe name of the authorthe name of the authoror the botanist whoor the botanist who
identified the plantidentified the plantThe binomial name of many plant can neverThe binomial name of many plant can never
be used to another plantbe used to another plant. .29
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II-- Biological Origin ( cont.)Biological Origin ( cont.)
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Atropa belladonna L. Atropa acuminata
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Genus
name
Starts with capital letter
Species Starts with small letter
Genusspecies
or Genus species (Underlined or written initalic).
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Atropa belladonna or Atropa belladonnanot
atropa Belladonna &
Atropa Belladonna
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The species sometimes spelt with Capital letter
the personWhere the species is named after
who discovered the plant or bring its seed
e.g.
CinchonaCinchona LedgerianaLedgeriana .
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The botanical name of the drug is followed by
the name of the author who first described
the species or varieties.
e.g. Atropa belladonna L.L. or
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Atropa belladonna L.L.
(beautiful lady)
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e.g. Atropa , from atropos meaning the
name of the Greek fate that cuts the
thread of life, indicating the poisonous
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.
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IIII--Geographical OriginGeographical OriginHabitat of the drugHabitat of the drug
Is the region in which the plant or animalIs the region in which the plant or animal
yielding the drug grows or lives.yielding the drug grows or lives.
Indigenous plantsIndigenous plants Naturalized plantsNaturalized plants
CannabisCannabis indicaindica
-- Cotton is indigenous to America, naturalized in EgyptCotton is indigenous to America, naturalized in Egypt39
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IIIIII--Commercial OriginCommercial Origin
--Production& channels of tradeProduction& channels of trade
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1-Cultivation 2- Collection
3-Preparationof drug beforedrying
Preparation of CrudeDrugs
5- Packing
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4- Drying
6-Storage