boletín nanomedicina febrero 2011

NanomedicinaBoletín

generado por VIGIALE, IALE Tecnología.

Febrero 2011

INDICE

NOTICIAS

HIDDEN TEXT TO MARK THE BEGINNING OF THE TABLE OF CONTENTS

1. Gene fuelled transporter causes breast cancer cells to self-destruct 2

2. Nanoparticles that mimic viruses can stimulate long lasting immunity 2

3. Fingerprints of a gold cluster revealed 2

4. Virus-Mimicking nanoparticles can stimulate long-lasting immunity 2

5. Clues to mystery of preterm delivery 3

6. Tuning the collective properties of artificial nanoparticle supercrystals 3

7. NanoBioConnect: A new tool to accelerate commercialization of nanobiotechnology 3

8. Prótesis articulares más seguras 3

9. Engineered cells could usher in programmable cell therapies 3

10. Modified RNA creates stable therapeutic nanoparticles 4

11. Enabling nanoparticles to penetrate deeply in tumors 4

12. MIT engineers design new nanoparticle that could lead to vaccines 4

13. Simpler way of making proteins could lead to new nanomedicine agents 4

14. New technology in human trials to spot cardiac disease 5

15. Desarrollan un sistema de transporte de fármacos antitumorales 5

16. Magnetic nanoparticles could track transplanted neural stem cells following spinal injury 5

17. Tiny 'microworms' could be implanted under the skin for continuous medical monitoring 5

18. Fresh technology for new cell creation 5

19. Unos nanotransportadores consiguen pasar 6

20. Next-Generation sensor technology to be developed by Optiqua-NTU Partnership 6

21. Tracking neural stem cells 6

22. Circulating tumor cell detection may be enhanced by nanoparticles 6

23. Drug encapsulation and gene therapies use new data obtained on liposomes 7

24. Precise new sensor employs hydrogels 7

PATENTES 25. Patentes publicadas este mes 7

26. Origen de los principales actores del mes 8

27. Principales titulares de las patentes del mes 8

28. Principales temas tratados en las patentes del mes 9

29. Principales inventores que patentaron este mes 9

30. US20110033522A1: Reagents for inducing an immune response 10

31. US20110038939A1: Therapeutic stable nanoparticles 10

32. US20110033550A1: Nanoparticle carriers for drug administration 10

33. US20110044893A1: Vascular targets for detecting, imaging and treating .. 10

34. US20110027174A1: Nanotubes for cancer therapy and diagnostics 10

INDICE 35. WO2011019211A2: Silk nanofiber nerve conduit and method for producing thereof 11

36. WO2011017456A2: Localized delivery of nanoparticles for therapeutic and diagnostic applications 11

37. US20110045031A1: Use of buckysome or carbon nanotube for drug delivery 11

38. US20110045055A1: Medical devices containing therapeutic agents 12

39. DK0912734T3: Chimeric heteromultimer adhesins 12

40. WO2011017313A1: Method of administering non-viral nucleic acid vectors to the eye 12

41. WO2011017442A2: Anti-RSV immunogens and methods of immunization 12

42. WO2011017690A2: Intracellular delivery of contrast agents with functionalized nanoparticles 13

43. US20110038905A1: Skin anti-aging agent for external use 13

44. US20110034916A1: Nanoparticle-mediated microwave treatment methods 13

45. WO2011012867A1: A delivery system comprising a silicon-containing material 13

46. US20110033419A1: Methods and compositions for treating cancer 14

47. WO2011012721A1: Carrier linked pramipexole prodrugs 14

48. WO2011014562A1: Methods and devices for targeted injection of microspheres 14

49. WO2011019954A2: Intracochlear drug delivery to the central nervous system 14

50. US20110038900A1: Nanoparticles for use in pharmaceutical compositions 15

EVENTOS, CURSOS YSEMINARIOS 51. Concertation des nanorevetements (stakeholder dialogue on nanocoatings) 15

52. INRS Occupational Health Research Conference 2011 15

53. IV Conferencia Anual de las Plataformas Tecnológicas de Investigación Biomédica 15

54. Nanotubes and Nanocomposites 2011 16

55. ImagineNano 16

56. COIN Hosts Nanomedicine Commercialization Workshop 16

57. NanoManufacturing Conference & Exhibits 16

58. 2nd NanoDiaRA Seminar 16

59. Conference Innovation in Healthcare: from Research to Market 17

60. 5th Concertation and Consultation Workshop on Micro-Nano-Bio convergence Systems 17

61. Latin American Biomedical Nanotechnology Showcase 17

62. Seminar on Micro- and Nanotechnology Based Tools for Early Detection of Diseases 17

63. MicroMaterials Nanomechanical Testing Technical Seminar 18

64. Nanotechnologies et risques: responsabilités et assurances? 18

ARTÍCULOS-CIENTÍFICOS 65. Principales investigadores que publicaron este mes 18

INDICE 66. Principales entidades con publicaciones este mes 19

67. Principales temas tratados en los artículos científicos del mes 19

68. "Off-On" Electrochemical Hairpin-DNA-Based Genosensor 20

69. Biostability of y-Fe2O3 nano particles 20

70. Size and surface charge of gold nanoparticles.. 20

71. Problems and challenges in the development and validation of human cell-based assays.. 20

72. Solid lipid nanoparticles reduce systemic toxicity of docetaxel 20

73. Cellular response of RAW 264.7 to spray-coated multi-walled carbon nanotube films 21

74. Analysis of Amyloid-b; Peptides in cerebrospinal fluid samples by capillary electrophoresis 21

75. Human skin penetration of gold nanoparticles through intact and damaged skin 21

76. Hazard identification of particulate matter on vasomotor dysfunction and atherosclerosis 21

77. Contribution of nano-copper particles to in vivo liver dysfunction and cellular damage 22

78. Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions 22

79. An effective strategy for the synthesis of biocompatible gold nanoparticles 22

80. Spherical bioactive glass particles and their interaction with human mesenchymal stem cells 22

81. Human skin penetration of gold nanoparticles through intact and damaged skin 23

REPORTES, LIBROS,OTRASPUBLICACIONES 82. Nanotoxicology: An Interdisciplinary Challenge 23

83. Nanotechnology in Medicine - Pharma-Reports 23

84. La nanotecnología española se coloca a la vanguardia internacional del sector 23

85. Drug Regulation in the Modern Era 24

86. Nanotechnology in Drug Delivery - Technological Improvements and Novel Approaches 24

87. Biochips - Products, Applications, Technologies and End-use Markets Growth Analysis 24

88. Nanomedicines in Argentina 2011 24

NanomedicinaNOTICIAS

Gene fuelled transporter causes breast cancer cells to self-destruct

Publicada en Nanomedicine Research - News, 02/28/2011.

Scientists at Queen's University Belfast have shown that they can deliver a gene directly into breast cancer cellscausing them to self-destruct, using an innovative, miniscule gene transport system, according to research publishedFebruary 28 in the International Journal of Pharmaceutics.

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Nanoparticles that mimic viruses can stimulate long lastingimmunityPublicada el 02/28/2011.

Vaccine scientists say their "Holy Grail" is to stimulate immunity that lasts for a lifetime. Live viral vaccines such asthe smallpox or yellow fever vaccines provide immune protection that lasts several decades, but despite theirsuccess, scientists have remained in the dark as to how they induce such long lasting immunity.

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Fingerprints of a gold cluster revealedPublicada el 02/25/2011.

Nanometre-scale gold particles are currently intensively investigated for possible applications in catalysis, sensing,photonics, biolabelling, drug carriers and molecular electronics. The particles are prepared in a solution from goldsalts and their reactive gold cores can be stabilised with various organic ligands.

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Virus-Mimicking nanoparticles can stimulate long-lasting immunity

Publicada en Nanomedicine Research - News, 02/24/2011.

Vaccine scientists say their "Holy Grail" is to stimulate immunity that lasts for a lifetime. Live viral vaccines such asthe smallpox or yellow fever vaccines provide immune protection that lasts several decades, but despite theirsuccess, scientists have remained in the dark as to how they induce such long lasting immunity.

ver más...

Febrero 2011 Página 2

NanomedicinaClues to mystery of preterm deliveryPublicada el 02/24/2011.

Scientists know that calcifying nanoparticles are involved in many degenerative conditions including arthritis andatherosclerosis.

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Tuning the collective properties of artificial nanoparticlesupercrystalsPublicada el 02/24/2011.

Due to precise positioning of the NCs within a 3-D superlattice, such systems are frequently referred to assupercrystals (SCs) in analogy to crystals built of atoms.

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NanoBioConnect: A new tool to accelerate commercialization ofnanobiotechnologyPublicada el 02/24/2011.

The Center of Innovation for Nanobiotechnology (COIN) today announced the launch of an information-rich,comprehensive nanobiotechnology information portal available to the public called NanoBioConnect.

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Prótesis articulares más segurasPublicada el 02/24/2011.

Un grupo de investigadores del MIT está desarrollando recubrimientos para implantes médicos capaces de sercargados con múltiples medicamentos, incluyendo antibióticos que se liberan a través del tiempo.

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Engineered cells could usher in programmable cell therapiesPublicada el 02/24/2011.

In work that could jumpstart the promising field of cell therapy, in which cells are transplanted into the body to treat avariety of diseases and tissue defects.

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NanomedicinaModified RNA creates stable therapeutic nanoparticlesPublicada el 02/24/2011.

But by replacing a chemical group in the macromolecule, Dr. Guo says he and fellow researchers have found a wayto bypass RNase and create stable three-dimensional configurations of RNA, greatly expanding the possibilities forRNA in nanotechnology.

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Enabling nanoparticles to penetrate deeply in tumorsPublicada el 02/24/2011.

Now, a large team of researchers from the Massachusetts Institute of Technology, have developed a solution to thisproblem: multilayered, or multistage, nanoparticles that partially dissolve once they accumulate around tumors,leaving behind a payload of nanoparticles a mere one-tenth the size of the original delivery vehicle.

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MIT engineers design new nanoparticle that could lead to vaccinesPublicada el 02/24/2011.

The new particles, consist of concentric fatty spheres that can carry synthetic versions of proteins normally producedby viruses. These synthetic particles elicit a strong immune response comparable to that produced by live virusvaccines but should be much safer.

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Simpler way of making proteins could lead to new nanomedicineagentsPublicada el 02/23/2011.

Researchers have developed a simple method of making short protein chains with spiral structures that can alsodissolve in water, two desirable traits not often found together. Such structures could have applications as buildingblocks for self-assembling nanostructures and as agents for drug and gene delivery.

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NanomedicinaNew technology in human trials to spot cardiac diseasePublicada el 02/23/2011.

Cardiac disease is the focus of one of six ongoing major clinical trials of Rice's programmable bio-nano-chips(PBNCs).

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Desarrollan un sistema de transporte de fármacos antitumoralesPublicada el 02/20/2011.

Científicos mexicanos trabajan en el desarrollo de un sistema de transporte de fármacos citotóxicos, que permitiráinyectar de manera simultánea agentes de quimio y radioterapia, dirigidos específicamente a tumores y célulascancerosas, con lo que se reducirán los efectos tóxicos secundarios en tejidos y órganos sanos.

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Magnetic nanoparticles could track transplanted neural stem cellsfollowing spinal injuryPublicada el 02/18/2011.

Tracking magnetic nanoparticles attached to stem cells transplanted into spinal cords to heal injuries could be aneffective way to monitor the healing process non-invasively say UK scientists.

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Tiny 'microworms' could be implanted under the skin forcontinuous medical monitoringPublicada el 02/17/2011.

Researchers at MIT and Northeastern have come up with a new system for monitoring biomedical indicators -- suchas levels of sodium or glucose in the blood -- that could someday lead to implantable devices that would allow, forexample, people with diabetes to check their blood sugar just by glancing at an area of skin.

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Fresh technology for new cell creation


NanomedicinaPublicada el 02/16/2011.

Enter the MODPLEUV project, which brought together Austrian, Czech and Polish researchers to successfullydevelop a novel yet easy way to create nano-structured materials that would facilitate human cell development.MODPLEUV is supported by EUREKA, the European platform for research and development (R&D).

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Unos nanotransportadores consiguen pasarPublicada en Technology Review, 02/16/2011.

Un nuevo sistema de nanotransporte es capaz de colar tratamientos contra el cáncer a través de las defensas de lascélulas tumorales resistentes a los fármacos, ofreciendo esperanza a muchos pacientes de cáncer que se beneficianpoco de los tratamientos farmacológicos existentes.

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Next-Generation sensor technology to be developed by Optiqua-NTU PartnershipPublicada el 02/16/2011.

To enhance its contaminant-detection capability, Optiqua Technologies Pte Ltd is collaborating with NanyangTechnological University (NTU) to tap on its expertise in biomolecular sciences and sensor technology.

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Tracking neural stem cellsPublicada el 02/14/2011.

Magnetic nanoparticles could be used to track neural stem cells after a transplant in order to monitor how the cellsheal spinal injuries, say UCL scientsts.

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Circulating tumor cell detection may be enhanced by nanoparticlesPublicada el 02/14/2011.

Tiny gold particles can help doctors detect tumor cells circulating in the blood of patients with head and neck cancer,researchers at Emory and Georgia Tech have found.

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NanomedicinaDrug encapsulation and gene therapies use new data obtained onliposomesPublicada el 02/09/2011.

University of Granada scientists and the Spanish Higher Institute for Scientific Research (CSIC) have madesignificant progress in understanding lipid membranes, which are extensively employed in the development ofcosmetic and drug products, and which have potential application in the field of nanotechnology.

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Precise new sensor employs hydrogelsPublicada el 02/09/2011.

Researchers are developing a new type of biological and chemical sensor that has few moving parts, is low-cost andyet highly sensitive, sturdy and long-lasting.

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PATENTES

Patentes publicadas este mesPublicada el 02/28/2011.

Fuente: Espacenet, USPTO


NanomedicinaOrigen de los principales actores del mesPublicada el 02/28/2011.

Fuente: Espacenet, USPTO

Principales titulares de las patentes del mesPublicada el 02/28/2011.

Fuente: Espacenet, UPSTO


NanomedicinaPrincipales temas tratados en las patentes del mesPublicada el 02/28/2011.

Fuente: Espacenet, UPSTO

Principales inventores que patentaron este mesPublicada el 02/28/2011.

Fuente: Especenet, USPTO


NanomedicinaUS20110033522A1: Reagents for inducing an immune responsePublicada el 02/24/2011.

Inventor: Reinherz Ellis L. Titular: Dana Farber Cancer Inst Inc (EE.UU.); Harvard College (EE.UU.); MassachusettsInst Technology (EE.UU.)Resumen: The present disclosure relates to reagents and kits that are useful in a variety methods for inducing animmune response.

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US20110038939A1: Therapeutic stable nanoparticlesPublicada el 02/24/2011.

Inventor: Lvov Yuri. Titulares: Univ Northeastern; Louisiana Tech University Res Foundation a Division of LouisianaTech University Foundation (EE.UU.)Resumen: Stable colloid nanoparticles comprising poorly soluble drugs are disclosed.

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US20110033550A1: Nanoparticle carriers for drug administrationPublicada el 02/24/2011.

Inventor: Kalombo Lonji. Titular: CSIR (Sudáfrica)Resumen: The invention provides a process for the production of nanoparticle carriers for drug delivery.

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US20110044893A1: Vascular targets for detecting, imaging andtreating ..Publicada el 02/24/2011.

Inventor y Titular: Schnitzer Jan E (EE.UU.)Resumen: Methods of delivering an agent in a tissue-specific manner, by targeting annexin A1, a derivative ofannexin A1, or a binding partner of annexin A1, are described.

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US20110027174A1: Nanotubes for cancer therapy and diagnostics



Inventor y Titular: Buzatu Dan A (EE.UU.).Resumen: The present invention provides a novel approach to cancer therapy and diagnostics that utilizes nanotubesand other similar nanostructures.

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WO2011019211A2: Silk nanofiber nerve conduit and method forproducing thereofPublicada el 02/24/2011.

Inventor: Park Young Hwan. Titular: Snu R&Db Foundation (Corea del Sur).Resumen: The present invention relates to a silk nanofiber nerve conduit characterized in that fibroin nanofibers, arestacked layer upon layer to form a porous conduit-shape; and a method for producing thereof.

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WO2011017456A2: Localized delivery of nanoparticles fortherapeutic and diagnostic applicationsPublicada el 02/24/2011.

Inventor: Mirkin Chad A. Titular: Univ Northwestern (EE.UU.)Resumen: The present invention is directed to compositions and methods of localized delivery of a functionalizednanoparticle.

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US20110045031A1: Use of buckysome or carbon nanotube for drugdeliveryPublicada el 02/24/2011.

Inventor: Hirsch Andreas. Titular: Ensysce Biosciences Inc (EE.UU.)Resumen: Compositions and methods for administering a therapeutic agent to a mammal are disclosed.

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NanomedicinaUS20110045055A1: Medical devices containing therapeutic agents

Publicada el 02/24/2011.

Inventor: Hingston John. Titular: Boston Scient Scimed Inc (EE.UU.)Resumen: According to one aspect of the invention, implantable or insertable medical devices are provided whichcan delay release of one or more therapeutic agents for a predetermined time after implantation in a subject.

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DK0912734T3: Chimeric heteromultimer adhesinsPublicada el 02/24/2011.

Inventor: Sliwkowski Mark. Titular: Genentech Inc (EE.UU.)Resumen: Chimeric heteromultimer adhesins that bind the ligand of natural heteromultimeric receptors and usestherefor are disclosed.

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WO2011017313A1: Method of administering non-viral nucleic acidvectors to the eyePublicada el 02/24/2011.

Inventor: Cooper Mark J. Titular: Copernicus Therapeutics Inc (EE.UU.)Resumen: Intravitreal administration of nucleic acid vectors leads to transfection and expression of the nucleic acidvectors in retinal pigment epithelium.

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WO2011017442A2: Anti-RSV immunogens and methods ofimmunizationPublicada el 02/24/2011.

Inventor: Anderson Larry J. Titular: US Government (EE.UU.)Resumen: Immunogenic polypeptides corresponding to one or more RSV G glycoproteins, or analogues thereof, areprovided as components of vaccines.

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NanomedicinaWO2011017690A2: Intracellular delivery of contrast agents withfunctionalized nanoparticlesPublicada el 02/24/2011.

Inventor: Mirkin Chad A. Titular: Univ Northwestern (EE.UU.)Resumen: The present invention is directed to compositions and methods for intracellular delivery of a contrast agentwith a functionalized nanoparticle.

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US20110038905A1: Skin anti-aging agent for external usePublicada el 02/24/2011.

Inventores: Aimi Makiko. Titular: Fujifilm Corp (Japón)Resumen: The present invention provides a skin anti-aging agent for external use, which comprises proteinnanoparticles containing an active ingredient.

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US20110034916A1: Nanoparticle-mediated microwave treatmentmethodsPublicada el 02/24/2011.

Inventor y Titular: Te Alexis. Titulares(EE.UU.)Resumen: A method is provided for using magnetic nanoparticles to enhance microwave therapies for treating cellsand tissues.

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WO2011012867A1: A delivery system comprising a silicon-containing materialPublicada el 02/24/2011.

Inventor: Saffie-Siebert Roghieh. Titular: Sisaf Ltd (Reino Unido)Resumen: A composition comprising nanoparticles of a hydrolysable silicon-contain material for use as a deliverysystem for a bioactive ingredient and a method of promoting the controlled release of orthosilicic acid.

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NanomedicinaUS20110033419A1: Methods and compositions for treating cancer

Publicada el 02/24/2011.

Inventor: Aurellan Laure. Titular: Univ Maryland (EE.UU.)Resumen: The invention further relates to pharmaceutical compositions comprising HSV-2 virus, wherein the viruslacks protein kinase activity of ICP10.

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WO2011012721A1: Carrier linked pramipexole prodrugsPublicada el 02/23/2011.

Inventor: Rau Harald. Titular: Ascendis Pharma AS (Dinamarca)Resumen: The present invention relates to a carrier linked pramipexole prodrug or a pharmaceutical acceptable saltthereof, wherein pramipexole is bound via a linker to a polymeric carrier.

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WO2011014562A1: Methods and devices for targeted injection ofmicrospheresPublicada el 02/23/2011.

Inventor: Kleinstreuer Clement. Titular: Univ North Carolina State (EE.UU.)Resumen: A "Smart Micro-catheter" (SMC) system comprising a device for controlled particle release and drugdelivery into a blood vessel, hepatic artery or any patho-physiological target is disclosed.

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WO2011019954A2: Intracochlear drug delivery to the centralnervous systemPublicada el 02/23/2011.

Inventor: Ivri Yehuda. Titular: Ivri Yehuda (EE.UU.)Resumen: The present invention is directed to method and system for delivery of brain-targeted drugs to thecerebrospinal fluid via the perilymphatic fluid of the inner ear.

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NanomedicinaUS20110038900A1: Nanoparticles for use in pharmaceuticalcompositionsPublicada el 02/22/2011.

Inventor: Chakrapani Aravind. Titular: Novartis AG (Suiza)Resumen: In various aspects of the present invention, nanoparticle compositions are provided which comprise (a)nanoparticles comprising at least one biodegradable polymer and (b) at least one pharmaceutical associated with thenanoparticles.

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EVENTOS, CURSOS Y SEMINARIOS

Concertation des nanorevetements (stakeholder dialogue onnanocoatings)Publicada en NanoForum.org-Events, 02/28/2011.

Pour enrichir lexpertise par la concertation, progresser dans lécoute et la compréhension des autres points de vues(parties apprenantes) et approfondir les controverses.Fecha: 15 March 2011 Lugar: Paris, France

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INRS Occupational Health Research Conference 2011Publicada el 02/23/2011.

Occupational Health Research Conference 2011: Risks associated to Nanoparticles and Nanomaterials.Fecha: 05 - 07 April 2011 Lugar: Nancy, France

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IV Conferencia Anual de las Plataformas Tecnológicas deInvestigación BiomédicaPublicada el 02/23/2011.

La cita anual de las tres Plataformas Tecnológicas de Investigación Biomédica bordará la cooperación farma-biotech,como una necesidad puesta de manifiesto en el modelo de investigación de nuevos medicamentos y tecnologíassanitarias.Fecha: 28 de febrero - 1 de marzo de 2011 Lugar: Palacio Municipal de Congresos de Madrid.

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NanomedicinaNanotubes and Nanocomposites 2011Publicada el 02/23/2011.

Will focus on research and development in all nano-particles, polymer processing and application, as well as marketdirection, growth and potential for commercialisation.Fecha: April 06 - 07, 2011 Lugar: Le Meridien Brussels, Brussels, Belgium

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ImagineNanoPublicada el 02/23/2011.

Extensive thematic conferences will be held in parallel and a huge industrial exhibition carried out with the latestnanotrends for the future. Fecha: Apr 11 - 14, 2011 Lugar: Bilbao, España

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COIN Hosts Nanomedicine Commercialization WorkshopPublicada el 02/23/2011.

The topic of the workshop will be Actionable Strategies for Company Building & Moving to Market.Fecha: Mar 29, 2011 Lugar: Charlotte North Carolina, EE.UU.

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NanoManufacturing Conference & ExhibitsPublicada el 02/23/2011.

This conference will highlight the current, near-term, and future applications of nanotechnology and how they aretransforming the way we manufacture products.Fecha: Apr 05 - 06, 2011 Lugar: Oakbrook Terrace (Chicago) IL, EE.UU.

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2nd NanoDiaRA SeminarPublicada el 02/23/2011.

NanoDiaRA, a consortium of 15 partners, is looking forward to welcoming interested people from research anddevelopment, industry and society and to show you new approaches of in-vitro and in-vivo technologies.Fecha: 18 March 2011 Lugar: Neuchâtel, Switzerland

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Nanomedicina

Conference Innovation in Healthcare: from Research to MarketPublicada el 02/23/2011.

The objective of the 2011 conference is to produce an analysis of the strengths, weaknesses, opportunities andthreats (SWOT) for innovation in healthcare and make specific recommendations that will be addressed to policy-makers and stakeholders.Fecha: 30-31 March 2011 Lugar: Brussels

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5th Concertation and Consultation Workshop on Micro-Nano-Bioconvergence SystemsPublicada el 02/23/2011.

Co-organized by the European Commission and IKERLAN-IK4 a private not-profit Technological Research Centre inthe north of Spain. Fecha: April 05 - 06, 2011 Lugar: Mondragón, Spain.

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Latin American Biomedical Nanotechnology ShowcasePublicada el 02/23/2011.

Workshop participants must be registered users of ICPC-Nanonet. Registration is free.Fecha: 23 March 2011Lugar: in internet, Great Britain

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Seminar on Micro- and Nanotechnology Based Tools for EarlyDetection of DiseasesPublicada en European Technology Platform of Nanomedicine - Events, 02/18/2011.

NanoDiaRA, a consortium of 15 partners, is looking forward to welcoming interested people from research anddevelopment, industry and society and to show you new approaches of in-vitro and in-vivo technologies.Fecha: 07 March 2011 Lugar: Neuchâtel, Switzerland

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NanomedicinaMicroMaterials Nanomechanical Testing Technical SeminarPublicada en AzoNanotechnology-Eventos, 02/18/2011.

Each Micro Materials Nanomechanical Testing Technical Seminar will provide an introduction to the theory, currentresearch and live demonstrations.Fecha: March 01, 2011 Lugar: Oxford University Begbroke Science Park, EE.UU.

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Nanotechnologies et risques: responsabilités et assurances?Publicada en NanoForum.org-Events, 02/18/2011.

Organized by: VivagoraFecha: 22 March 2011Lugar: Paris, France

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ARTÍCULOS-CIENTÍFICOS

Principales investigadores que publicaron este mesPublicada el 02/28/2011.

Fuente: Scopus


NanomedicinaPrincipales entidades con publicaciones este mesPublicada el 02/28/2011.

Fuente: Scopus

Principales temas tratados en los artículos científicos del mesPublicada el 02/28/2011.

Fuente: Scopus


Nanomedicina"Off-On" Electrochemical Hairpin-DNA-Based GenosensorPublicada el 02/23/2011.

Autor: Farjami E.Resumen: A simple and robust "off-on" signaling genosensor platform with improved selectivity for single-nucleotidepolymorphism (SNP) detection based on the electronic DNA hairpin molecular beacons has been developed.

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Biostability of y-Fe2O3 nano particlesPublicada el 02/23/2011.

Autor: Kwon-Jai Leea. Resumen: This study examined the cytotoxic effects of the y-Fe2O3 magnetic nanoparticles(GMNs) on a range of tumor cell lines.

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Size and surface charge of gold nanoparticles..Publicada el 02/23/2011.

Autor: Schleh C. Resumen: In this study, radiolabelled gold nanoparticles in different sizes (1.4200 nm) with negativesurface charge and 2.8 nm nanoparticles with opposite surface charges were administered by intra-oesophagealinstillation into healthy adult female rats.

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Problems and challenges in the development and validation ofhuman cell-based assays..Publicada el 02/23/2011.

Autor: Oostingh GJ. Resumen: In a collaborative work between European laboratories, existing immunological andtoxicological in vitro assays were tested and compared for their suitability to test effects of nanoparticles on immuneresponses.

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Solid lipid nanoparticles reduce systemic toxicity of docetaxel



Autor: Gao Y. Resumen: In this study, the new docetaxel-loaded solid lipid nanoparticles (DSNs) were prepared, andsystemic toxicity of DSNs in different animals was comprehensively investigated for allergenicity and vascularirritation in mice and beagle dogs.

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Cellular response of RAW 264.7 to spray-coated multi-walled carbonnanotube filmsPublicada el 02/23/2011.

Autor: Chen H. Resumen: In this paper, the authors studied the potential health effect of carbon nanotube (CNT) filmsfabricated with three commercial surfactants (sodium cholate, sodium dodecyl sulfate, and triton X-100).

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Analysis of Amyloid-b; Peptides in cerebrospinal fluid samples bycapillary electrophoresisPublicada el 02/23/2011.

Autor: Verpillot R. Resumen: We report a CE-LIF method for the separation and detection of five synthetic amyloid-beta; peptides corresponding to an important family of CSF-biomarkers in the context of Alzheimer disease (AD).

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Human skin penetration of gold nanoparticles through intact anddamaged skinPublicada el 02/23/2011.

Autor: Larese Filon F. Resumen: In this study, experiments were performed with gold nanoparticles (AuNPs) usingthe Franz diffusion cell method with intact and damaged human skin.

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Hazard identification of particulate matter on vasomotordysfunction and atherosclerosis



Autor: Pøller. Resumen: The development and use of nanoparticles have alerted toxicologists and regulators toissues of safety testing.

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Contribution of nano-copper particles to in vivo liver dysfunctionand cellular damagePublicada el 02/23/2011.

Autor: Manna P. Resumen: In this study, the oxidative stress responsive cell signaling in nano-copper-inducedhepatic dysfunction and cell death was investigated.

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Differential pro-inflammatory effects of metal oxide nanoparticlesand their soluble ionsPublicada el 02/23/2011.

Autor: Cho WS. Resumen: In this study, nickel, zinc, and copper oxide nanoparticles (NiONP, ZnONP, and CuONP)and their aqueous extracts (AEs) were applied to A549 lung epithelial cells to determine the cytotoxicity, IL-8production, and activation of transcription factors.

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An effective strategy for the synthesis of biocompatible goldnanoparticlesPublicada el 02/23/2011.

Autor: Chanda N. Resumen: In this study, cinnamon-coated gold nanoparticles (Cin-AuNPs) were synthesized by a"green" procedure, and the detailed characterization was performed by physico-chemical analysis.

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Spherical bioactive glass particles and their interaction with humanmesenchymal stem cellsPublicada el 02/23/2011.

Autor: Labbaf S. Resumen: In this study, sub-micron particles of bioactive glass (SMBGs) were synthesised andcharacterised and the effect of exposure of SMBGs to human mesenchymal stem cells (hMSCs) on cell viability,metabolic activity and proliferation were determined using the LIVE/DEAD, MTT, total DNA and LDH assays.


Nanomedicinaver más...

Human skin penetration of gold nanoparticles through intact anddamaged skinPublicada en Virtual Journal of Nanotechnology Environment, Health and Safety, 02/16/2011.

Autor: Larese Filon F. Resumen: In this study, experiments were performed with gold nanoparticles (AuNPs) usingthe Franz diffusion cell method with intact and damaged human skin.

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REPORTES, LIBROS, OTRAS

Nanotoxicology: An Interdisciplinary ChallengePublicada el 02/23/2011.

This Review seeks to cast light on the phenomena that may occur as nanoobjects interact with cells, tissues, andorganisms and points out the aspect of reliability of studies with specific examples from the literature including adiscussion of inadequate methods together with recommendations how to avoid this in the future.

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Nanotechnology in Medicine - Pharma-ReportsPublicada el 02/23/2011.

Nanotechnology is already being used in products in its passive form, such as cosmetics and sunscreens, and it isexpected that in the coming decades, new phases of products, such as better batteries and improved electronicsequipment, will be developed and have far©\reaching implications.

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La nanotecnología española se coloca a la vanguardia internacionaldel sectorPublicada el 02/23/2011.

El objetivo del Plan Nacional de I+D+i del Gobierno 2008-2011, es mejorar la competitividad de la industria españolamediante la generación de cambios sustanciales en un amplio rango de sectores a través de la implementación y eldesarrollo de nuevas aplicaciones y convergencias de diferentes tecnologías y disciplinas, entre las que destacan lananociencia y nanotecnología (N&N).


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Drug Regulation in the Modern EraPublicada el 02/23/2011.

Remarks of Margaret A. Hamburg, M.D. Commissioner of Food and Drugs

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Nanotechnology in Drug Delivery - Technological Improvementsand Novel ApproachesPublicada el 02/23/2011.

The report provides a comprehensive insight into the role of Nanotechnology in Drug Delivery. The report alsoprovides a detailed analysis of market characterization of nanotechnology in drug delivery market in terms of itsmarket size, segmentation by key geography types and the major market drivers and barriers.

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Biochips - Products, Applications, Technologies and End-useMarkets Growth AnalysisPublicada el 02/23/2011.

Global Market Watch: Global biochips market is forecasted to reach US$9.1 billion by 2015 with a CAGR of 20.9%during 2009-2015; the massive CAGR is primarily supported by Asia-Pacific followed by the European Union.

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Nanomedicines in Argentina 2011Publicada el 02/15/2011.

Alejandro Sosnik and Eder Romero present their personal view of the current Nanomedicine landscape in Argentina.

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boletín nanomedicina febrero 2011

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