boletín nanomedicina abril 2011

NanomedicinaBoletín

generado por VIGIALE, IALE Tecnología.

Abril 2011

INDICE

NOTICIAS

HIDDEN TEXT TO MARK THE BEGINNING OF THE TABLE OF CONTENTS

1. NANO-systems to accelerate recovery after surgery without side effects 2

2. Nanotechnology for the treatment of coronary in stent restenosis: A clinical perspective 2

3. Sandia and UNM lead effort to destroy cancers 2

4. Nanoscience may hold key to surgical recovery 2

5. Scientists engineer nanoscale vaults to encapsulate 'nanodisks' for drug delivery 3

6. Promising data demonstrating the anti-tumor activity of a novel cancer target 3

7. Stanford research moves nanomedicine one step closer to reality 3

8. Pediatric Center Focuses on Nano-Medicine for Pediatric Care 3

9. IBM nanomedicine breakthrough to aid antibiotics 4

10. Nanofiber spheres show promise for knee cartilage repair 4

11. Nanotech device identifies cancer and HIV 4

12. Nanotechnology vehicle speeds numbing of topical lidocaine 4

13. Injectable gel could spell relief for arthritis sufferers 4

14. DNA stretching: new technique to detect illnesses 5

15. Pre-clinical results for oral delivery of the anti-cancer drug 5

16. New DNA nanoforms take shape 5

17. NCKU and NRC made innovative cancer diagnostic and treatment discoveries 5

18. Nanofiber spheres carrying cells injected into wounds to grow tissue 6

19. First look at the mechanics of membrane proteins 6

20. Nanoscience used to identify cancer drug effectiveness 6

21. The world's smallest wedding rings 6

22. Hand-held NMR instrument yields rapid analysis of human tumors 7

23. Nanoparticles enhance detection of circulating tumor cells 7

24. 'Good cholesterol' nanoparticles seek and destroy cancer cells 7

25. Study develops new approaches for sorting out complexities of cancer cells 7

26. Chemical engineers at UCSB design molecular probe to study disease 8

27. Personalized therapies for inflammation 8

28. Study ways to improve treatment of inflammatory bowel disease 8

29. La batalla entre microRNAs y oncogenes 8

PATENTES 30. Patentes publicadas este mes 9

31. Origen de los principales actores del mes 9

32. Principales temas tratados en las patentes del mes 10

33. Principales titulares de las patentes del mes 10

34. Principales inventores que patentaron este mes 11

INDICE 35. US20110097401A1: Methods for treating gastrointestinal disorders 11

36. US20110091560A1: Compositions of nanoparticles and methods of making the same 11

37. US20110091373A1: PAA nanoparticles for enhancement of tumor imaging 12

38. US20110097277A1: Particles coated with zwitterionic polymers 12

39. US20110093020A1: Poly-porous hollow screw for target delivery of growth factors... 12

40. WO2011050357A2: Protein arginine deiminase inhibitors for rheumatoid arthritis and cancer 12

41. US20110097377A1: Methods and devices for correcting spinal deformity... 13

42. US20110093089A1: Electronically controlled prosthetic system 13

43. US20110097420A1: Cement products and methods of making and using the same 13

44. US20110091353A1: Methods for sterilizing tissue 13

45. US20110098558A1: System and method for use of nanoparticles imaging and diagnosis 14

46. WO2011048493A1: Coated capsules and tablets of fatty acid oil mixture 14

EVENTOS, CURSOS YSEMINARIOS 47. Smart Polymer Systems 2011 14

48. EuroNanoForum 2011 14

49. European Perspectives in Personalised Medicine 15

50. 6th Intl Congress of Nano Bio Clean Tech 15

51. 4th European-Conference for Clinical Nanomedicine 15

52. Nanotech Conference and Expo 2011 15

53. Nanomedicine 2011 - 3rd ESF Summer School 16

54. Greener Nano 2011 16

55. EuroNanoForum 2011 16

56. European Perspectives in Personalised Medicine 16

57. Safety issues of Nanomaterials along their life cycle Symposium 16

58. 7th International Dendrimer Symposium 17

59. Biomedical Nanotechnology 17

60. Nanomaterials 2011 17

61. EUPOC 2011, Biobased Polymers and Related Biomaterials 17

62. Biomedical Applications in Nanotechnology 18

63. NanoBio-Europe 2011 18

64. III Simposio sobre Nanotecnologías CINVESTAV/Sigma Aldrich 18

65. Conferencia Internacional IMMUNONET: Las Nuevas Tendencias en Inmunoterapia 18

66. Nanotech China 19

ARTÍCULOS-CIENTÍFICOS

INDICE 67. Artículos científicos publicados este mes 19

68. Principales temas tratados en los artículos científicos del mes 20

69. Principales entidades con publicaciones este mes 20

70. Principales investigadores que publicaron este mes 21

71. Balancing forces: architectural control of mechanotransduction 21

72. Supramolecular self-assembly of biopolymers with carbon nanotubes for biomimetic... 21

73. Dual temperature/pH-sensitive drug delivery of poly... nanogels 22

74. Positive potential operation of a cathodic... immunosensor for cancer biomarker detection 22

75. Intracellular pH sensing using p-aminothiophenol functionalized gold nanorods... 22

76. Quantum dot-aptamer nanoprobes for recognizing and labeling influenza A virus particles 22

77. Lithography-based nanoelectrochemistry 23

78. Transport of single cells using an actin bundlemyosin bionanomotor transport system 23

79. DNA origami with complex curvatures in three-dimensional space 23

80. Biostability of y-Fe2O3 nano particles ..cytotoxicity assays on various tumor cell lines 23

81. Activation of neural and pluripotent stem cell signatures... 24

82. Controlled growth and differentiation of MSCs on grooved films assembled ... 24

83. Validation of the calibrated thrombin generation test (cTGT)... 24

84. Drug delivery: One nanoparticle, one kill 24

85. Specific penetration and accumulation of a homing peptide within atherosclerotic plaques 24

86. Application of fiber optic ATR-FTIR methods.. for therapeutic delivery systems 25

87. Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer 25

88. SiRNA delivery with exosome nanoparticles 25

89. Reactions inside nanoscale protein cages 25

NORMATIVAS 90. CEN ISO/TS 13830:2011 26

91. Nanoscale carbon toxicity testing proposal submitted to EPA 26

92. ASTM WK32796 - New Test Method 26

INFORMES Y OTRASPUBLICACIONES 93. Molecular Diagnostics in Cancer Testing 27

94. Market Analyst Dissects Global Nano-medicine Market 27

95. Ethical and Societal Aspects of Nanotechnology Enabled ICT and Security Technologies 27

96. Nanotechnology Research Directions for Societal Needs in 2020 Retrospective and Outlook 27

97. Double-walled carbon nanotubes for medical imaging by MRI and other biomedical applications 28

98. Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future ... 28

NanomedicinaNOTICIAS

NANO-systems to accelerate recovery after surgery without sideeffectsPublicada en Azonano - Noticias sobre Nanomedicina, 04/29/2011.

By Cameron ChaiThe University of York research team at the Department of Chemistry has created artificialmolecules that can attach the chemical drug heparin that could replace protamine.

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Nanotechnology for the treatment of coronary in stent restenosis: Aclinical perspectivePublicada en Nanotechnology Now, 04/28/2011.

Coronary in stent restenosis remains a significant limitation to the long term efficacy of coronary artery stentplacement. In this review the authors review the pathophysiology of coronary instent restenosis, together with anoverview of the current treatment modalities.

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Sandia and UNM lead effort to destroy cancersPublicada en Nanotechwire.com - Bio/Medicine, 04/28/2011.

Melding nanotechnology and medical research, Sandia National Laboratories, the University of New Mexico, and theUNM Cancer Research and Treatment Center have produced an effective strategy that uses nanoparticles to blastcancerous cells with a mélange of killer drugs.

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Nanoscience may hold key to surgical recoveryPublicada en Science Daily - Nanomedicina, 04/28/2011.

Researchers from the University of York's Department of Chemistry have developed synthetic molecules capable ofbinding the chemical drug heparin, which they believe may provide an alternative to protamine.

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Abril 2011 Página 2

NanomedicinaScientists engineer nanoscale vaults to encapsulate 'nanodisks' fordrug deliveryPublicada en Nanotechwire.com - Drug Delivery, 04/28/2011.

In recent years, researchers have grappled with the challenge of administering therapeutics in a way that boosts theireffectiveness by targeting specific cells in the body while minimizing their potential damage to healthy tissue.

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Promising data demonstrating the anti-tumor activity of a novelcancer targetPublicada el 04/22/2011.

Tekmira Pharmaceuticals Corporation, a leading developer of RNA interference (RNAi) therapeutics, announcedtoday that promising preclinical data from its collaboration with the National Cancer Institute (NCI) has beenpublished in Oncogene, one of the world's leading cancer journals.

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Stanford research moves nanomedicine one step closer to realityPublicada el 04/20/2011.

A class of engineered nanoparticles gold-centered spheres smaller than viruses has been shown safe whenadministered by two alternative routes in a mouse study led by investigators at the Stanford University School ofMedicine. This marks the first step up the ladder of toxicology studies that, within a year and a half, could yield tohuman trials of the tiny agents for detection of colorectal and possibly other cancers.

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Pediatric Center Focuses on Nano-Medicine for Pediatric CarePublicada el 04/18/2011.

Researchers at the Center for Pediatric Nanomedicine (CPN) will design specific, nanoparticles in an endeavor totreat pediatric illnesses. Focus will be on pediatric heart disease and thrombosis, infectious diseases, cancer, sicklecell disease and cystic fibrosis.

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NanomedicinaIBM nanomedicine breakthrough to aid antibioticsPublicada el 04/18/2011.

IBM researchers and scientists from the Institute of Bioengineering and Nanotechnology on Sunday unveiled ananomedicine breakthrough biodegradable nanoparticles that make antibiotics physically attracted to infected cells.

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Nanofiber spheres show promise for knee cartilage repairPublicada en Nanomedicine Research - News, 04/18/2011.

Using injectable hollow, biodegradable nanofiber spheres as cell carriers is likely to repair knee cartilage moreeffectively than current methods, said US researchers in a paper published online in Nature Materials this week.

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Nanotech device identifies cancer and HIVPublicada en BSI -Nanotechnology news, 04/18/2011.

A new device has been created by scientists from Harvard University and the Massachusetts Institute of Technology(MIT) that is capable of detecting cancer cells and indicators of HIV in blood. Using carbon nanotubes to create postsmeasuring 30 microns in diameter, the team has developed technology that is capable of catching tiny objects flowingthrough a microfluidic system.

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Nanotechnology vehicle speeds numbing of topical lidocainePublicada en Nanotechnology Now, 04/18/2011.

A 4% topical lidocaine cream with a nanotechnology-based vehicle in development provided superior pain reliefbefore facial filler injections, compared with the most commonly-used topical anesthetic cream, according to patientand physician ratings in two split-face studies.

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Injectable gel could spell relief for arthritis sufferers


NanomedicinaPublicada en Nanotechwire.com - Bio/Medicine, 04/18/2011.

Researchers from Brigham and Womens Hospital have developed a potentially new way to treat arthritis. Here theirnew gel (red, with yellow rectangles representing encapsulated medicine) is injected into an arthritic joint. Thereenzymes (black image) associated with arthritis break down the biodegradable gel, releasing the medicine.

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DNA stretching: new technique to detect illnessesPublicada en Science Daily - Nanomedicina, 04/18/2011.

Scientists are making DNA sequences being passed through nanochannels a thousand times thinner than a humanhair to the point that they take on the form of diminutive spaghetti. This is an innovative technique, known as DNAstretching, and is one of the lines of research in which CIC microGUNE is working, and about which they havealready published two scientific articles and are shortly to apply for a patent.

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Pre-clinical results for oral delivery of the anti-cancer drugPublicada en Nanotechwire.com - Drug Delivery, 04/18/2011.

Yissum Research Development Company Ltd., the technology transfer company of the Hebrew University ofJerusalem, announced today successful pre-clinical data of oral delivery of Docetaxel, an anti-cancer drug, utilizing anovel nanotechnology platform.

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New DNA nanoforms take shapePublicada el 04/18/2011.

Miniature architectural forms have been constructed through a revolutionary technique known as DNA origami. Now,Hao Yan, Yan Liu and their colleagues at Arizona State University's Biodesign Institute have expanded the capabilityof this method to construct arbitrary, two and three-dimensional shapes, mimicking those commonly found in nature.

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NCKU and NRC made innovative cancer diagnostic and treatmentdiscoveries


NanomedicinaPublicada el 04/18/2011.

A Taiwanese research team led by Prof. Dar-Bin Shieh of Institute of Oral Medicine in Medical College at NationalCheng Kung University (NCKU) has partnered with a research group led by Dr. Dennis Whitefield from NationalResearch Council (NRC) of Canada to develop innovative cancer diagnostic and treatment technologies.

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Nanofiber spheres carrying cells injected into wounds to growtissuePublicada el 04/18/2011.

For the first time, scientists have made star-shaped, biodegradable polymers that can self-assemble into hollow,nanofiber spheres, and when the spheres are injected with cells into wounds, these spheres biodegrade, but the cellslive on to form new tissue.

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First look at the mechanics of membrane proteinsPublicada el 04/18/2011.

In two new studies, researchers provide the first detailed view of the elaborate chemical and mechanical interactionsthat allow the ribosome - the cell's protein-building machinery - to insert a growing protein into the cellular membrane.

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Nanoscience used to identify cancer drug effectivenessPublicada el 04/18/2011.

The effectiveness of treatments for cancer could be better assessed using nanotechnology, it has been claimed. Ascientist in Indiana in the US has been experimenting with nanopolymers and has discovered they could help todetermine whether or not drugs are reaching the intended site.

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The world's smallest wedding ringsPublicada el 04/18/2011.

Prof Alexander Heckel and his doctoral student Thorsten Schmidt from the "Cluster of Excellence for MacromolecularComplexes" at Goethe University were able to create two rings of DNA only 18 nanometers in size, and to interlockthem like two links in a chain. Such a structure is called catenan, a term derived from the Latin word catena (chain).


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Hand-held NMR instrument yields rapid analysis of human tumorsPublicada el 04/18/2011.

Using a handheld molecular imaging device in combination with magnetic nanoparticles and a smartphone, a team ofinvestigators from the Massachusetts General Hospital and Harvard Medical School has developed a fast, portableand potentially inexpensive method of detecting cancer from human biopsy samples.

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Nanoparticles enhance detection of circulating tumor cellsPublicada el 04/18/2011.

Circulating tumor cells (CTCs), shed into the blood stream by tumors, are thought to provide a means of detectingcancer early, conducting a preliminary assessment of which anticancer agents might prove most effective at treatinga given patient, and assessing whether a chosen therapy is working.

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'Good cholesterol' nanoparticles seek and destroy cancer cellsPublicada el 04/18/2011.

High-density lipoprotein's hauls excess cholesterol to the liver for disposal, but new research suggests "goodcholesterol" can also act as a special delivery vehicle of destruction for cancer.

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Study develops new approaches for sorting out complexities ofcancer cellsPublicada el 04/18/2011.

New drugs that specifically target the mutated genes responsible for cancer growth have shown great success inextending the lives of patients, with far fewer side effects than conventional anti-cancer therapies. Unfortunately,many patients become resistant to these drugs due to secondary mutations.

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NanomedicinaChemical engineers at UCSB design molecular probe to studydiseasePublicada el 04/18/2011.

Chemical engineers at UC Santa Barbara expect that their new process to create molecular probes may eventuallyresult in the development of new drugs to treat cancer and other illnesses.

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Personalized therapies for inflammationPublicada el 04/18/2011.

Scientists at Barts and The London School of Medicine and Dentistry and Harvard Medical School, Boston havefound a way of mimicking the body's natural mechanism of fighting inflammation. During inflammation cells releasevery small particles termed 'microparticles' that retain features of their parent cell.

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Study ways to improve treatment of inflammatory bowel diseasePublicada el 04/18/2011.

CEA-Leti today announced a new project designed to develop a novel nanocarrier-based approach to improve thetreatment of inflammatory bowel disease, and increasingly common condition in Europe.

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La batalla entre microRNAs y oncogenesPublicada el 04/18/2011.

La prestigiosa revista Blood publica en su último numero un artículo del Grupo de División Celular y Cáncer delCNIO, que dirige Marcos Malumbres, en el que se da cuenta de la batalla que libran los microRNAs -pequeñosfragmentos de RNA- por modular y controlar la actividad de determinados oncogenes y evitar así que las células seconviertan en cancerosas.

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NanomedicinaPATENTES

Patentes publicadas este mesPublicada el 04/30/2011.

Fuente: Espacenet, USPTO

Origen de los principales actores del mesPublicada el 04/30/2011.

Fuente: Espacenet, USPTO


NanomedicinaPrincipales temas tratados en las patentes del mesPublicada el 04/30/2011.

Fuente: Espacenet, UPSTO

Principales titulares de las patentes del mesPublicada el 04/30/2011.

Fuente: Espacenet, UPSTO


NanomedicinaPrincipales inventores que patentaron este mesPublicada el 04/30/2011.

Fuente: Especenet, USPTO

US20110097401A1: Methods for treating gastrointestinal disorders

Publicada el 04/29/2011.

Inventor: Phillips Elaine. Titular: Meritage Pharma Inc (US). Resumen: Provided herein are compositions andformulations suitable for the treatment of gastrointestinal disorders. Also provided are methods for treating,preventing, or alleviating disorders of the gastrointestinal tract, for example, those involving the esophagus.

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US20110091560A1: Compositions of nanoparticles and methods ofmaking the samePublicada el 04/29/2011.

Inventor: Smith Jeff (US). Titular: Burhnam Inst Medical Research (US). Resumen: Disclosed herein arecompositions of nanoparticles. In some embodiments, the nanoparticles are Janus particles, where each particleincludes a first component and second component that are exposed to the surface of the particle.

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NanomedicinaUS20110091373A1: PAA nanoparticles for enhancement of tumorimagingPublicada el 04/29/2011.

Inventor: Pandey Ravindra K. Titulares: Health Research Inc (US), Unic New York State Res Found (US); UnivMichigan (US). Resumen: A composition comprising PAA nanoparticles containing a post loaded tetrapyrollicphotosensitizer and an imaging agent and methods for making and using same.

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US20110097277A1: Particles coated with zwitterionic polymersPublicada el 04/29/2011.

Inventor: Jiang Shaoyi. Titular: Univ Washington (US). Resumen: Nanoparticles zwitterionic polymers grafted theretoor grafted therefrom, and methods for making and using the nanoparticles. Zwitterionic nanogels, and methods formaking and using the nanogels.

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US20110093020A1: Poly-porous hollow screw for target delivery ofgrowth factors...Publicada el 04/29/2011.

Inventor y Titular: Wu Yangguan (US). Resumen: Present invention depicts a poly-porous (micropore) hollow screwsas diffusion chamber filled with core matrix for targeted delivery of growth factors and bone marrow stem cells. Thescrews comprise at least two parts: the distal part of the screw consists of the tip of the screw made of poly porousmaterial and hollow inside proximally.

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WO2011050357A2: Protein arginine deiminase inhibitors forrheumatoid arthritis and cancerPublicada el 04/29/2011.

Inventor: Thompson Paul R. Titular: Univ South Carolina (US). Resumen: In accordance with certain embodiments ofthe present disclosure, a self-assembling biodegradable nanoparticle is provided. The nanoparticle includes Cys-Val-Val-Val-Val-Val-Val-Lys-Lys conjugated with a synthetic polymer and has a diameter of from about 50 nm to about150 nm.

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NanomedicinaUS20110097377A1: Methods and devices for correcting spinaldeformity...Publicada el 04/29/2011.

Inventor y Titular: Serhan Hassan (US). Resumen: A method of correcting spinal deformity, which includes locatingpharmaceutical-loaded implants adjacent to targeted spinal growth plates, and then eluting the pharmaceutical ontothe growth plates. Preferably, the method involves correcting spinal deformity by simply inserting a pharmaceutical-eluting pedicle screw onto the concave side of a scoliotic curve.

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US20110093089A1: Electronically controlled prosthetic systemPublicada el 04/29/2011.

Inventor y Titular: Martin James J (US). Resumen: A prosthetic joint system for users comprising a housing having aninterior cavity, a center axis in said interior cavity, and an attachment means for fixedly connecting said housing tosaid user...

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US20110097420A1: Cement products and methods of making andusing the samePublicada el 04/29/2011.

Inventor: Lin Juchui Ray. Titular: Angstrom Medica (US). Resumen: Disclosed are cement products, methods offorming cement using the cement product, and methods of using the cement product in orthopedic and dentalapplications.... cement product includes a first component comprising a polymerizable resin .....optionally, the cementproduct includes a bioactive component to promote bone formation.

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US20110091353A1: Methods for sterilizing tissuePublicada el 04/29/2011.

Inventor y Titular: Burgess Wilson (US). Resumen: Methods are disclosed for sterilizing tissue to reduce the level ofone or more active biological contaminants or pathogens therein, such as viruses, bacteria, yeasts, molds, fungi,prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. Themethods involve sterilizing one or more tissues with irradiation.

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NanomedicinaUS20110098558A1: System and method for use of nanoparticlesimaging and diagnosisPublicada el 04/29/2011.

Inventor: Weaver John B. Titular: Dartmouth College The Trustees (US). Resumen: A method for diagnosing certaintypes of cancers provides a nanoparticle agent to be uptaken by cancer cells for diagnosis and treatment of certaincancers. A compound containing nanoparticles is directed toward a tumor site, and then a predetermined time periodpasses to allow the nanoparticles to be uptaken by the cancer cells.

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WO2011048493A1: Coated capsules and tablets of fatty acid oilmixturePublicada el 04/29/2011.

Inventor: Klaveness JO Erik Johnsrud (NO). Titular: Pronova Biopharma Norge AS (NO). Resumen: Compositionscomprising a fatty acid oil mixture and at least one free fatty acid in a coated capsule or a coated tablet form suitablefor oral administration, and methods of use thereof, are disclosed.

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EVENTOS, CURSOS Y SEMINARIOS

Smart Polymer Systems 2011Publicada en AzoNanotechnology-Eventos, 04/28/2011.

The conference aims to provide a comprehensive overview of the current state-of-the-art in the field anddemonstrate, via a range of case studies and contributions from leading researchers, how companies might capitaliseon this emerging technology.Fecha: May 25 - 26, 2011. Lugar: Mainz, Germany.

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EuroNanoForum 2011Publicada el 04/18/2011.

EuroNanoForum is a biannual event supported by the European Commission and organised within the framework ofthe Presidency of the European Union.Fecha: 30 May -1 June 2011. Lugar: Budapest, Hungary.

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NanomedicinaEuropean Perspectives in Personalised MedicinePublicada el 04/18/2011.

This conference will bring together key stakeholders of the research community and the healthcare sector to identifythe developments needed in order to contribute to the research for Personalised Medicine at European and nationallevel, in the frame of the Innovation Union and beyond.Fecha: 12 - 13 May 2011. Lugar: Brussels, Belgium.

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6th Intl Congress of Nano Bio Clean TechPublicada el 04/18/2011.

The conference will gather world class researchers, business executives and engineers from over 30 countries andcover the following topics: Nanomaterials, Nanobiotechnology, Molecular Engineering, Heath Safety Implications,Intellectual Property, Commercialization, Venture capital investment and other related topics.Fecha: June 20, 2011. Lugar: San Francisco, CA, USA.

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4th European-Conference for Clinical NanomedicinePublicada el 04/18/2011.

The conference focuses on clinical application of novel developments innanoscience but also includes industrialtopics, the expertise formregulatory authorities and discussion on ethical questions and widerimplications.Fecha: 23 May, 2011. Lugar: Basel, Switzerland.

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Nanotech Conference and Expo 2011Publicada el 04/18/2011.

Uniting innovators to bring nanotechnology from laboratory to marketplace. Nanotech 2011 brings together over5,000 technology and business leaders and experts from academia, government, startups and Fortune 1,000companies.Fecha: June 13, 2011. Lugar: Boston, MA, USA.

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NanomedicinaNanomedicine 2011 - 3rd ESF Summer SchoolPublicada el 04/18/2011.

The ESF Summer School Nanomedicine 2011, has been designed to provide an intensive state-of the- art trainingacross all of the sub-disciplines of Nanomedicine, and to foster discussion and exchange of ideas in a relaxedatmosphere.Fecha: June 19-24, 2011. Lugar: Wittenberg, Germany.

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Greener Nano 2011Publicada el 04/18/2011.

We will focus on two key research areas: highlight state-of-the-art in materials synthesis and characterizationchallenges, and discuss biological impacts of nanotechnology.Fecha: May 01 - 03, 2011. Lugar: Cupertino California, USA

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EuroNanoForum 2011Publicada el 04/18/2011.

EuroNanoForum is a biannual event supported by the European Commission and organised within the framework ofthe Presidency of the European Union.Fecha: May 30 - June 01, 2011. Lugar: Budapest, Hungary.

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European Perspectives in Personalised MedicinePublicada el 04/18/2011.

This conference will bring together key stakeholders of the research community and the healthcare sector to identifythe developments needed in order to contribute to the research for Personalised Medicine.Fecha: 12-13 May 2011. Lugar: Square-Brussels Meeting Centre, Brussels

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Safety issues of Nanomaterials along their life cycle Symposium



The aim of the Symposium is to discuss about the human and environmental impacts of nanomaterials along their lifecycle from their production through their processing, use, and end of life (recycling and/or disposal). Fecha: 4-5 May,2011. Lugar: Terrassa, Barcelona, Spain.

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7th International Dendrimer SymposiumPublicada el 04/18/2011.

An average of 300-400 participants attended these symposium from over 30 countries every two years.Thesymposium focuses on the scientific research, latest developments in technology, synthesis, characterizationandapplications.Fecha: June 26 - July 1, 2011. Lugar: Gaithersburg, Maryland, USA.

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Biomedical NanotechnologyPublicada en AzoNano-Nanomaterial Courses, 04/18/2011.

Biomedical Nanotechnology is a course that investigates key areas in which nanotechnology can benefit biomedicalapplications, understanding of nanomaterials for various biomedical applications, wet and dry nanotechnology, andbasics of nanofabrication. This course also introduces applications such as drug delivery, imaging and diagnostics,and tissue regeneration and engineering.Fecha: Continual. Lugar: online.

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Nanomaterials 2011Publicada en NanoConferences.com, 04/18/2011.

NanoMaterials 2011 will feature 2 plenary sessions and 3 parallel sessions with a change in focus from the previouseditions. These 3 programme tracks will focus on: Policy, Business & Finance; and Synthesis and production...Fecha: June 07 - 09, 2011. Lugar: London, UK.

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EUPOC 2011, Biobased Polymers and Related Biomaterials


NanomedicinaPublicada en NanoForum.org-Events, 04/18/2011.

The aims of this Conference are to review the present state of research in the area of biobased/biorelated polymers,and to provide a forum for discussion of future progress and prospect. Chemistry, physics and application ofbiobased/biorelated polymers and polymeric biomaterials will be covered.Fecha: 29 May 2011 - 03 June 2011. Lugar: Gargnano, Italy.

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Biomedical Applications in NanotechnologyPublicada en NanoMicroClub - Events, 04/18/2011.

This workshop will provide an overview of some of the latest developments in applying nanotechnology to a range ofimportant medical and lifescience applications including biosensing, clinical diagnostics, medical imaging,regenerative medicine and drug delivery.Fecha: 26 May 2011. Lugar: Glasgow, UK

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NanoBio-Europe 2011Publicada el 04/18/2011.

The 7th NanoBio-Europe conference will be hosted in Cork (Ireland), showcasing the latest internationaldevelopments in nanobiotechnology, and providing a platform to facilitate interdisciplinary communications, newcollaborations for delegates from academic, industrial and clinical backgrounds.Fecha: 21 - 23 June 2011. Lugar: Cork, Ireland.

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III Simposio sobre Nanotecnologías CINVESTAV/Sigma AldrichPublicada el 04/18/2011.

Nanotecnologías en Biología, Química yCiencias de Materiales.Fecha: 11 y 12, mayo 2011. Lugar: México DF, México.

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Conferencia Internacional IMMUNONET: Las Nuevas Tendencias enInmunoterapia



Coincidiendo con su 5ª reunión, la red de Inmunoterapia IMMUNONET ha organizado un taller sobre las nuevastendencias en Inmunoterapia.Fecha: 20 May 2011. Lugar: Majadahonda, Madrid, Spain.

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Nanotech ChinaPublicada el 04/18/2011.

Prestigious professors and scholars from Chinese National Nano Center and Chinese Society of MicronanoTechnology, Many world-known companies will discuss and address on the most recent research results onmicronano technology, and dissertations on the most advanced studying equipment will also be given by world-famous equipment suppliers.Fecha: 07 - 09 June 2011. Lugar: Shanghai, China.

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ARTÍCULOS-CIENTÍFICOS

Artículos científicos publicados este mesPublicada el 04/30/2011.

Fuente: Scopus


NanomedicinaPrincipales temas tratados en los artículos científicos del mesPublicada el 04/30/2011.

Fuente: Scopus

Principales entidades con publicaciones este mesPublicada el 04/30/2011.

Fuente: Scopus


NanomedicinaPrincipales investigadores que publicaron este mesPublicada el 04/30/2011.

Fuente: Scopus

Balancing forces: architectural control of mechanotransductionPublicada en Nanomedicine Research Publicaciones, 04/28/2011.

Autor: Dufort CC. Resumen: All cells exist within the context of a three-dimensional microenvironment in which theyare exposed to mechanical and physical cues. These cues can be disrupted through perturbations tomechanotransduction, from the nanoscale-level to the tissue-level, which compromises tensional homeostasis topromote pathologies such as cardiovascular disease and cancer.

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Supramolecular self-assembly of biopolymers with carbonnanotubes for biomimetic...Publicada en RSC - Nanoscale latest articles, 04/26/2011.

Autor: Luhua Lu. Resumen: Biopolymers are important natural multifunctional macromolecules for biomimetic andbio-inspired advanced functional material design. They are not only simple dispersants for carbon nanotubestabilization as they have been found to have specific interactions with carbon nanotubes.

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NanomedicinaDual temperature/pH-sensitive drug delivery of poly... nanogelsPublicada el 04/26/2011.

Autor: Xiong W. Resumen: In this paper, a dual temperature/pH-sensitive poly(N-isopropylacrylamide-co-acrylic acid)nanogel (PNA) was prepared and utilized as a drug carrier. The anti-cancer drug doxorubicin (DOX) was covalentbound to PNA via an acid-labile hydrazone linkage.

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Positive potential operation of a cathodic... immunosensor forcancer biomarker detectionPublicada el 04/22/2011.

Autor: Xu S. Resumen: In this work, we report a cathodic electrogenerated chemiluminescence (ECL) of luminol at apositive potential (ca. 0.05 V vs Ag/AgCl) with a strong light emission on the graphene-modified glass carbonelectrode.

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Intracellular pH sensing using p-aminothiophenol functionalizedgold nanorods...Publicada el 04/22/2011.

Autor: Zong S. Resumen: We report an intracellular pH sensor based on surface enhanced Raman scattering (SERS)using the hydrochloric acid (HCl) treated gold nanorods (GNRs) as the SERS substrates and p-aminothiophenol(pATP) as the Raman reporter.

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Quantum dot-aptamer nanoprobes for recognizing and labelinginfluenza A virus particlesPublicada el 04/21/2011.

Autor: Cui ZQ. Resumen: The fluorescence labeling of viruses is a useful technology for virus detection and imaging.By combining the excellent fluorescence properties of quantum dots (QDs) with the high affinity and specificity ofaptamers, we constructed a QD-aptamer probe.

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NanomedicinaLithography-based nanoelectrochemistryPublicada el 04/21/2011.

Autor: Rassaei L. Resumen: Lithographically fabricated nanostructures appear in an increasingly wide range ofscientific fields, and electroanalytical chemistry is no exception. This article introduces lithography methods andprovides an overview of the new capabilities and electrochemical phenomena that can emerge in nanostructures.

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Transport of single cells using an actin bundlemyosinbionanomotor transport systemPublicada en IOPscience: latest papers, 04/19/2011.

Autor: Hideyo Takatsuki. Resumen: The potential of using actin bundles for the transport of liposomes and singlecells across myosin-coated surfaces is investigated. Compared to that observed with filamentous actin, the liposometransport using actin bundles was more linear in nature and able to occur over longer distances.

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DNA origami with complex curvatures in three-dimensional spacePublicada en Nanomedicine Research Publicaciones, 04/18/2011.

Autor: Han D. Resumen: We present a strategy to design and construct self-assembling DNA nanostructures thatdefine intricate curved surfaces in three-dimensional (3D) space using the DNA origami folding technique. Double-helical DNA is bent to follow the rounded contours of the target object, and potential strand crossovers aresubsequently identified.

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Biostability of y-Fe2O3 nano particles ..cytotoxicity assays onvarious tumor cell linesPublicada en Virtual Journal of Nanotechnology Environment, Health and Safety, 04/18/2011.

Autor: Lee KJ. Resumen: This study examined the cytotoxic effects of the y-Fe2O3 magnetic nanoparticles (GMNs)on a range of tumor cell lines.

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NanomedicinaActivation of neural and pluripotent stem cell signatures...Publicada el 04/18/2011.

Autor: J Holmberg. Resuemn: The presence of stem cell characteristics in glioma cells raises the possibility thatmechanisms promoting the maintenance and self-renewal of tissue specific stem cells have a similar function intumor cells.

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Controlled growth and differentiation of MSCs on grooved filmsassembled ...Publicada el 04/18/2011.

Autor: Zhu H. Resumen: The search for a cell-supporting scaffold with controlled topography and surface chemistry isa constant topic within tissue engineering. Here we have employed M13 phages, which are genetically modifiablebiological nanofibers non-toxic to human beings, to form films for supporting the growth of mesencymal stem cells(MSCs).

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Validation of the calibrated thrombin generation test (cTGT)...Publicada el 04/18/2011.

Autor: Laloy J. Resumen: In this study, a preclinical toxicological screening assay was validated and guidelines toevaluate the potential impact of nanoparticles (NPs) on blood coagulation are provided.

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Drug delivery: One nanoparticle, one killPublicada el 04/18/2011.

Autor: Darrell J. Resumen: By wrapping a ligand-functionalized lipid membrane around a silica core, nanoparticleswith a fluid surface are created. These combine unprecedented specificity in binding to cancer cells with thecombinatorial delivery of drug cocktails.

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Specific penetration and accumulation of a homing peptide withinatherosclerotic plaques



Autor: J Hamzah. Resumen: The ability to selectively deliver compounds into atherosclerotic plaques would greatlybenefit the detection and treatment of atherosclerotic disease. We describe such a delivery system based on a 9-amino acid cyclic peptide, LyP-1. LyP-1 was originally identified as a tumor-homing peptide...

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Application of fiber optic ATR-FTIR methods.. for therapeuticdelivery systemsPublicada el 04/18/2011.

Autor: CL McFearin. Resumen: A fiber optic coupled ATR-FTIR spectroscopy technique was applied to the study oftwo different therapeutic delivery systems, acid degradable hydrogels and nanoparticles. Real time exponentialrelease of a model protein, human serum albumin (HSA)...

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Preclinical screening of anti-HER2 nanobodies for molecularimaging of breast cancerPublicada el 04/18/2011.

Autor: I Vaneycken. Resumen: Accurate determination of tumor human epidermal growth factor receptor 2 (HER2)-status in breast cancer patients is possible via noninvasive imaging, provided adequate tracers are used. In thisstudy, we describe the generation of a panel of 38 nanobodies, small HER2-binding fragments that are derived fromheavy-chain-only antibodies raised in an immunized dromedary.

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SiRNA delivery with exosome nanoparticlesPublicada el 04/18/2011.

Autor: JG van den Boorn. Resumen: A natural system for ferrying RNA between cells is used to transport siRNA tothe mouse brain.

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Reactions inside nanoscale protein cages


NanomedicinaPublicada en RSC - Nanoscale latest articles, 04/03/2011.

Autor: Saskia A. Resumen: Chemical reactions are traditionally carried out in bulk solution, but in nature confinedspaces, like cell organelles, are used to obtain control in time and space of conversion. One way of studying thesereactions in confinement is the development and use of small reaction vessels dispersed in solution, such as vesiclesand micelles.

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NORMATIVAS

CEN ISO/TS 13830:2011Publicada en European Committee for Standardization (CEN) , 04/18/2011.

Guidance on the labelling of manufactured nano-objects and products containing manufactured nano-objects

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Nanoscale carbon toxicity testing proposal submitted to EPAPublicada en ANSI - Nanotechnology Law Report, 04/07/2011.

The NanoSafety Consortium for Carbon just submitted a proposed toxicity testing agreement to EPA under Section 4of the Toxic Substances Control Act covering a range of nanoscale materials including multi-walled carbonnanotubes, double-walled carbon nanotubes, single-walled carbon nanotubes, and graphene.

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ASTM WK32796 - New Test MethodPublicada en ASTM International's Committee E56 on Nanotechnology New Workitems, 04/07/2011.

New test method for measurement of airborne metal and metal oxide nanoparticle surface area in inhalationexposure chambers using gas adsorption.

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NanomedicinaINFORMES Y OTRAS

Molecular Diagnostics in Cancer TestingPublicada en Biotechnology Market Research Reports, 04/30/2011.

This TriMark Publications report describes the specific segment of the in vitro diagnostics (IVD) market known asmolecular diagnostics (MD), with a specialization in the MD tests for cancer. In the current medical diagnosticsmarket, molecular diagnostics for cancer testing offers one of the brightest areas for growth and innovation.

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Market Analyst Dissects Global Nano-medicine MarketPublicada en European Platform of Nanomedicine Presentaciones, 04/28/2011.

A recent RNCOS research report titled, Nanotechnology Market Forecast to 2013, states that the globalnanomedicine market is estimated to grow at a CAGR of 13% in 2009 through 2013.

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Ethical and Societal Aspects of Nanotechnology Enabled ICT andSecurity TechnologiesPublicada en Nanoforum.org - Reports, 04/28/2011.

In this report, public debates and literature on ethical and societal aspects of nanotechnology in ICT and security, andcivil-military dual use aspects of nanotechnology are discussed. The main aim is to identify new or persistent issuesin these debates that merit the attention of policy makers responsible for nanotechnology in Europe.

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Nanotechnology Research Directions for Societal Needs in 2020Retrospective and OutlookPublicada en Australian Research Council Nanotechnology Network (ARCNN) Publications, 04/18/2011.

The National Science Foundation(NSF) and the World Technology Evaluation Center(WTEC) have conducted astudy on Nanotechnology Research directions titled "Nanotechnology Research Directions for Societal Needs in 2020Retrospective and Outlook.

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NanomedicinaDouble-walled carbon nanotubes for medical imaging by MRI andother biomedical applicationsPublicada el 04/18/2011.

Tesis doctoral. Carbon nanotubes (CNT) represent a great hope for different biomedical applications (drug delivery,controlled release, vaccines, medical imaging). The potential toxicity of CNT should however not be ignored and theNanocomposites and Carbon Nanotubes (NCN) team at the CIRIMAT has participated as one of the leaders in thisfield (3 PhD students already, coordination of a national "ANR" programme, participation to the CARBIO Marie CurieRTN, etc.).

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Design of biocompatible dendrimers for cancer diagnosis andtherapy: current status and future perspectivesPublicada el 04/18/2011.

In the past decade, nanomedicine with its promise of improved therapy and diagnostics has revolutionizedconventional health care and medical technology. Dendrimers and dendrimer-based therapeutics are outstandingcandidates in this exciting field as more and more biological systems have benefited from these starburst molecules.

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boletín nanomedicina abril 2011

Technology

conferencia

framework

6th intl congress

fiber optic

biannual event

unm lead effort

intracellular

publicada