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  • BLOOD & BLOOD PRODUCT

    PROCEDURES

    MANUAL

    Northern Area Health Service

    &

    North West Area Health Service

    August 2011

  • Page - 2 - of 80

    CONTENTS

    GLOSSARY.......................................................................................................................................................................... - 4 -

    DECISION TO TRANSFUSE .................................................................................................................................................. - 5 -

    APPROPRIATENESS ................................................................................................................................................................ - 5 -

    MULTILINGUAL CONSUMER INFORMATION ...................................................................................................................................... - 6 -

    JEHOVAHS WITNESSES ................................................................................................................................................................ - 7 -

    CHILDREN & NEONATES ........................................................................................................................................................ - 9 -

    ADMINISTRATION.............................................................................................................................................................. - 9 -

    PRESCRIPTION OF BLOOD COMPONENTS AND BLOOD PRODUCTS .................................................................................. - 11 -

    ROUTINE / OUT HOURS BLOOD TRANSFUSION ............................................................................................................................... - 12 -

    AUTOLOGOUS BLOOD ............................................................................................................................................................... - 13 -

    AUTOLOGOUS BLOOD ............................................................................................................................................................... - 13 -

    SPECIALISED BLOOD PRODUCTS .......................................................................................................................................... - 13 -

    IRRADIATED PRODUCTS .................................................................................................................................................. - 13 -

    REQUESTS FOR BLOOD PRODUCTS & PRE-TRANSFUSION BLOOD SAMPLING .................................................................. - 15 -

    CROSS MATCHING & GROUP & HOLD .......................................................................................................................................... - 16 -

    STORAGE COLLECTION AND TRANSPORT OF BLOOD PRODUCTS ..................................................................................... - 17 -

    TRANSFER OF BLOOD PRODUCTS ACCOMPANYING PATIENTS TO ANOTHER HOSPITAL ..................................................... - 17 -

    ADMINISTRATION OF BLOOD PRODUCTS ........................................................................................................................ - 18 -

    NAHS & NWAHS-MASSIVE TRANSFUSION GUIDELINES (MTG) ...................................................................................................... - 18 -

    CONCURRENT FLUIDS AND MEDICATIONS .......................................................................................................................... - 19 -

    Compatible fluids ............................................................................................................................................................ - 19 -

    Incompatible fluids .......................................................................................................................................................... - 19 -

    Medications..................................................................................................................................................................... - 19 -

    EXCHANGE TRANSFUSION .......................................................................................................................................................... - 21 -

    EQUIPMENT ............................................................................................................................................................................ - 22 -

    Blood Component and Blood Product Administration Sets ............................................................................................. - 22 -

    Infusion Devices............................................................................................................................................................... - 24 -

    Blood Warmers ............................................................................................................................................................... - 25 -

    Rapid Infusion ................................................................................................................................................................. - 26 -

    MANAGEMENT AND REPORTING OF ADVERSE EVENTS ................................................................................................... - 27 -

    ADVERSE REACTIONS TO TRANSFUSION ........................................................................................................................................ - 27 -

    CLINICAL GOVERNANCE ................................................................................................................................................... - 29 -

    STAFF TRAINING REQUIREMENTS ................................................................................................................................................. - 29 -

    SPECIFIC RESPONSIBILITIES .................................................................................................................................................. - 30 -

    FRESH BLOOD COMPONENT ............................................................................................................................................ - 32 -

    RED CELLS FOR TRANSFUSION .................................................................................................................................................... - 32 -

    PLATELETS FOR TRANSFUSION ..................................................................................................................................................... - 35 -

  • Blood and Blood Products Transfusion Procedure Manual

    - 3 -

    FRESH FROZEN PLASMA (FFP) FOR TRANSFUSION .......................................................................................................................... - 39 -

    CRYOPRECIPITATE FOR TRANSFUSION ........................................................................................................................................... - 42 -

    PLASMA DERIVED FRACTIONATED PRODUCTS ................................................................................................................. - 45 -

    MIX2VIAL HOW TO USE: ......................................................................................................................................................... - 45 -

    BIOSTATE ................................................................................................................................................................................ - 47 -

    PROTHROMBINEX-VF ................................................................................................................................................................ - 48 -

    GUIDELINES FOR THE MANAGEMENT OF AN ELEVATED INR IN ADULTS ................................................................................................. - 49 -

    HUMAN RH (D) IMMUNOGLOBULIN (ANTI-D) ............................................................................................................................... - 52 -

    WINRHO SD ........................................................................................................................................................................... - 55 -

    HUMAN ALBUMIN 4% & 20% ................................................................................................................................................... - 58 -

    HUMAN INTRAVENOUS IMMUNOGLOBULIN INFUSIONS (IVIG) ........................................................................................................ - 61 -

    General IVIG Administration Recommendations ............................................................................................................ - 61 -

    Intragam P ...................................................................................................................................................................... - 63 -

    Flebogamma ................................................................................................................................................................... - 65 -

    Octagam ......................................................................................................................................................................... - 69 -

    ADDITIONAL RESOURCES/REFERENCES ........................................................................................................................... - 73 -

    APPENDIXES ....................................................................................