Baylor University Medical Center at Dallas is a major patient care, teaching and research center for the Southwest and one of the largest medical centers in the Dallas-Fort Worth area. Since 1983, Baylor Dallas has developed an outstanding reputation for patient care and clinical research in blood and marrow transplantation.

Blood and Marrow Transplant Physicians on the Medical Staff

3410 Worth St.Dallas, TX 75246214.820.3535 1.800.9BAYLOR BaylorHealth.com/DallasCancer

Edward D. Agura, MDMedical Director, Blood and Marrow Transplant ServicesDr. Agura is board certified in internal medicine, hematology and oncology with 25 years of experience. He graduated from New York University School of Medicine. His internship and residency in internal medicine were completed at Boston City Hospital. A fellowship in hematology at Boston University/Boston City Hospital was followed by a fellowship in oncology and hematology at the Fred Hutchinson Cancer Research Center in Seattle.

R. Brian Berryman, MDMedical Director, Blood and Marrow Transplant Outreach Program/Clinics Dr. Berryman is board certified in internal medicine and medical oncology, with more than 10 years of experience. He completed his medical school education, internship and residency at the University of Texas Southwestern Medical Center at Dallas. His fellowship in hematology and oncol-ogy was done at UT Southwestern and the Fred Hutchinson Cancer Research Center in Seattle.

Carolina Escobar, MDDr. Escobar is board certified in internal medicine, hematol-ogy and oncology. She received her medical education from the Universidad Pontificia Bolivariana and completed her internship and residency at Louisiana State University Health Science Center (LSUHSC). She also completed a fellowship in hematology and oncology at LSUHSC and a blood and marrow transplant fellowship at Baylor University Medical Center at Dallas.

Joseph W. Fay, MDDirector of Immunological Therapy for Cancer, Baylor Institute for Immunology Research; Hematopoietic Cell Transplantation and Therapeutics, Baylor Research InstituteDr. Fay received his MD from the Ohio State University Medical School. He did his post-MD training at Duke University Medical Center and the National Cancer Insti-tute. He is board certified in hematology and oncology. Before coming to Dallas, he was assistant professor of medicine at Duke University, where he started the blood and marrow transplant program in 1977.

Dr. Fay established the BMT program at Baylor University Medical Center in 1982 and played an important role in the establishment of the Foundation for the Accreditation of Hematopoietic Cell Therapy (FACT) in the United States.

Alan Miller, MD, PhDChief of Oncology for Baylor Health Care System and Medical Director of Baylor Charles A. Sammons Cancer Center at DallasDr. Miller received his PhD in physiology in the Roswell Park Division of the State University of New York at Buffalo and his MD at the University of Miami. He completed his internal medicine residency and fellowship in medical oncology at the University of Florida. He previously served as associate senior vice president for Health Sciences and interim senior vice president for Health Sciences at Tulane University.

Luis A. Piñeiro, MDMedical Director for Bone Marrow Processing Lab and Special Blood Services Lab; Associate Medical Director of Bone Marrow Transplant ProgramDr. Piñeiro is board certified in internal medicine and hematology, with more than 20 years of experience. He completed his medical education at the University of Puerto Rico School of Medicine. His internship and residency in internal medicine were completed at the Veterans Administration Medical Center in San Juan, Puerto Rico, and his fellowship in hematology and oncology was completed at the Washington University School of Medicine in St. Louis. He is interested in the treatment of hematologic malignancies and stem cell transplantation and is fluent in Spanish.

Estil A. Vance III, MDDr. Vance is board certified in internal medicine, medical oncology and infectious diseases. He completed his medical education, internship and residency at the Johns Hopkins University School of Medicine in Baltimore. He completed fellowships at Harvard Medical School, Dana-Farber Cancer Institute and Brigham and Women’s Hospital, while receiving a master of medical science degree from Harvard/Massachusetts Institute of Technology. Dr. Vance joined the medical staff of Baylor University Medical Center at Dallas in September 1998 from the Dana-Farber Cancer Institute in Boston. In addition to his interest and experience in blood and marrow transplantation, he is an expert in the field of oncology-related infections. He also co-directs a specialty clinic in skin lymphomas in conjunction with Dr. Jennifer Cather.

Program Highlights• The Blood and Marrow Transplant (BMT) program at Baylor

Charles A. Sammons Cancer Center at Dallas has performed more than 5,000 adult bone marrow and blood stem cell transplants in the past 30 years.

• BMT physicians on the medical staff at Baylor Dallas performed North Texas’ first bone marrow transplant in 1983 and Texas’ first matched unrelated donor transplant in 1988.

• Is one of the 20 highest volume BMT Centers in the United States based on the number of transplants performed.

• Participation in numerous national clinical trials, including those of the National Institutes of Health Clinical Trials Network and pivotal studies in new drug development.

• Among the first programs in the United States to receive accreditation by the Foundation for the Accreditation of Cellular Therapy (FACT).

• Is distinguished as a Center of Excellence by multiple insurance carriers.

For More Information• General information for donors: 214.820.8165

• General information for patients: 214.370.1500

• Blood and Marrow Transplant Outpatient Clinic: 214.370.1500

• Virginia R. Cvetko Patient Education and Support Center: 214.820.2608

• Patient Navigator: 214.820.3535

3410 Worth St., Suite 300Dallas, TX 75246214.370.15001.888.864.ICAN (4226) texasoncology.com

Physicians provide clinical services as members of the medical staff at one of Baylor Scott & White Health’s subsidiary, community or affiliated medical centers and do not provide clinical services as employees or agents of those medical centers, Baylor Health Care System, Scott & White Healthcare or Baylor Scott & White Health. ©2015 Baylor Scott & White Health. SAMMONS_471_2014 Blood & Marrow Transplant Brochure. MOD 14122. 4/15. 300

An Introduction for

Patients and Families

BLOOD AND MARROW TRANSPLANT SERVICES Baylor Charles A. Sammons Cancer Center at Dallas

At 21, Candice Stinnett was mother to a young son and had recently begun a job she loved as an emergency dispatcher. Her own health was not at the top of her priority list. So when she felt a lump on the side of her neck that didn’t hurt, but wouldn’t go away, she didn’t think much of it. When she did get it examined, her doctor initially thought it was an infected lymph node and gave her antibiotics. Months later, however, nothing had changed and a biopsy was ordered. The result: non-Hodgkin’s lymphoma.

Candice was immediately fitted for a port to deliver chemotherapy medications. She received six rounds of chemo treatments, one every three weeks. Six months later, scans revealed the cancer was gone.

But by January of the next year, it had returned. This time, doctors recommended a peripheral blood stem cell transplant (BMT) to hopefully eradicate the cancer cells in her system. Although Stinnett has three sisters, none of them was an appropriate match for the transplant. A possible donor was found through Be The Match® Registry, but the potential donor was only a 70 percent match and lived out of the country. So her next best option was an autologous transplant in which Stinnett’s own peripheral blood stem cells are collected, cleaned and then reintroduced into her system. After more chemotherapy to shrink existing cancer cells and medication to boost production of existing healthy cells, the transplant took place in June 2009.

But her journey was not over just yet. At her one-year check up, the non-Hodgkin’s lymphoma had reared its ugly head again. “I was devastated when I was told the cancer was back again,” she says. “A few weeks later, I learned a donor was found and matched me almost perfectly. I was finally able to smile again and my future wasn’t a blur anymore. Someone signed up to save my life!”

The procedure to test and prepare the donor took approximately six weeks. During that time, Stinnett was given medication and more chemotherapy to keep her disease as small as possible. On Oct. 7, 2010, she received her donor’s stem cells and was able to return home Oct. 23. This time, she says she started to feel better and stronger day after day.

“Thanks to this donor, I have a different outlook on life,” she says.“I don’t let little things bother me and we dance every single day. I want to experience life with windblown hair and a spring in my steps.”

Patient and Program Benefits

Candice Stinnett

Experience and Quality CountSince its beginning in 1983, the Blood and Marrow Transplant (BMT) program at Baylor Charles A. Sammons Cancer Center at Dallas has performed more than 5,000 transplantations, ranking it among the largest in the country. The program has vast expertise in autologous, allogenic-related and allogenic-unrelated donor transplantation. Treatment is available for acute and chronic leukemia, Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, myeloma and related diseases, as well as selected solid tumors.

In 1998, the BMT program at Baylor Sammons Cancer Center at Dallas became one of the first in the United States to receive initial accreditation by the Foundation for the Accreditation of Cellular Therapy (FACT). The program has continued to maintain its accreditation. This recognition placed Baylor Sammons Cancer Center at Dallas among an elite group of BMT centers nationwide.

At Baylor Sammons Cancer Center at Dallas, patients have access to a comprehensive continuum of BMT services, including pre-transplant evaluation and treatment, inpatient and outpatient care, long-term follow-up care, education, support, housing coordination and financial services.

Unrelated Donor TransplantsIn 1988, Baylor Sammons Cancer Center at Dallas was the first in Texas to use unrelated donor bone marrow for bone marrow transplantation. The program now regularly considers and employs unrelated donor transplant options in the treatment of various conditions.

Haplo-Identical Transplantation For those patients who need a transplant and do not have a matched donor, our team is now performing haplo-identical (half-match) transplants. With this approach, almost everyone can find an appropriate donor (usually a parent, child or sibling).

Clinical and Basic Science ResearchResearch at Baylor Sammons Cancer Center at Dallas’ BMT program focuses on the design and implementation of novel treatment applications, such as mini-transplantation, studies of graft-versus-host disease, induction of immune tolerance, studies of supportive care for transplant recipients and studies in the prevention and treatment of infectious diseases. With many active studies, the program has many options available for BMT patients. Investigators with the BMT program are involved in investigational new drug projects approved by the U.S. Food and Drug Administration. As a result of Baylor Sammons Cancer

Center at Dallas’ steadfast participation in numerous research studies, some patients are able to benefit from new medications and treatments three to five years before they become standard therapy.

Reduced Intensity Transplantation Research Baylor Sammons Cancer Center at Dallas has been collaborating with the Fred Hutchinson Cancer Research Center in Seattle and other institutions for more than eight years in the promising field of reduced intensity transplantation. As a result of this collaboration, this type of treatment has become a standard therapy. Patients who are treated with this approach receive one-fifth the usual doses of chemotherapy and radiotherapy, thereby minimizing typical side effects and hospitalization. As a result, in most cases the procedure is performed on an outpatient basis. Reduced intensity transplantation is easier on the body than conventional transplantation and may offer new hope to older patients and those with frail health who may not have had transplantation as an option before.

Patient SupportPatient Care AreasInpatient—The BMT inpatient unit at Baylor T. Boone Pickens Cancer Hospital includes a 24-bed induction unit on the 7th floor and an additional 24-bed nursing unit on the 6th floor. An apheresis center on the 1st floor has eight bays with beds and an additional 12 infusion chairs and four infusion beds in the infusion center. All of the rooms are high-efficiency particulate air (HEPA)- filtered to provide optimal isolation from infection. These rooms also are designed for more comfort for the patient and family with space and an adjoining area for family to relax or work. A separate area in the hospital is also dedicated to family members to shower and wash and dry clothes without having to leave the facility. In addition, a dedicated pharmacy and multidisciplinary staff offices are located adjacent to the transplant inpatient unit.

Outpatient—Because of major advances in drug therapies, treatment regimens and technology, some patients no longer have to be admitted to the hospital for treatment. For those who have this option, outpatient transplantation offers the convenience of not being in the hospital and the comfort of sleeping in their own bed. Outpatients receive all the services of an inpatient unit, such as transfusions, chemotherapy, antibiotics, physician consultation, nutritional and social services. The Blood and Marrow Transplant Outpatient Center is located on the 3rd floor

of Baylor Sammons Cancer Center at Dallas. It is open seven days a week, 365 days a year. The average experience of the outpatient transplant nursing team is 17 years. The unit has 18 examination rooms, 32 infusion chairs and 18 private infusion rooms. A full-service laboratory is on site, as well as an on-site retail pharmacy for patient convenience.

Housing and Support ServicesHousing—All patients who live outside a 50-mile radius will be evaluated for their needs and matched with suitable housing options. In addition to Baylor Plaza Hotel and Arkhouse, patients have access to other housing options. A site close to Baylor Sammons Cancer Center at Dallas has been chosen as a future location for an American Cancer Society Hope Lodge. Planning is in progress.

Twice Blessed House—Recognized for excellence by transplant clients in OptumHealth’s Client Choice Award program, Twice Blessed House offers:

• A community of 46 fully furnished apartments where pre- and post-transplantation patients are provided a warm family atmosphere and amenities for daily living.

• A convenient location a few blocks from Baylor Sammons Cancer Center at Dallas, one block away from a DART train stop and less than 30 minutes from both Dallas/Fort Worth International Airport and Dallas Love Field Airport. It is also just down the street from Baylor Institute for Rehabilitation, where some patients may receive post-transplantation rehabilitation therapy.

• The opportunity for patients and their caregivers to build relationships with other transplantation patients through community activities such as weekly dinners, arts and craft nights, game nights, movie nights and various outings.

Education—The patient and his or her family are considered the focus of care. Because a well-informed patient is better equipped to make decisions regarding treatment options, patients and family members begin an intensive education process upon referral. A variety of tools are used to educate patients and families, including a comprehensive patient guidebook, pre-transplantation orientation class and one-on-one instructional lessons.

Psychosocial Support—Psychological and social support can be critical to successful outcomes. A master’s-degreed social worker assesses the patient and family during the pre-transplantation evaluation. This comprehensive assessment enables the social worker to provide access to the appropriate resources and communicate special patient needs to the multidisciplinary team members in coordination with the patient and family.

Support Programs—Care for the patient includes care for his or her family. The Virginia R. Cvetko Patient Education and Support Center offers education and support for both. Patients and their families are invited to participate in educational and support programs at the center, located in Suite 200 of Baylor Sammons Cancer Center at Dallas. These programs are led by members of the health care team, including oncology nurses, social workers, chaplains, pharmacists, dietitians and physical and recreational therapists.

Through the Cvetko Center, volunteers who are past transplant recipients visit patients one-on-one to provide encouragement and emotional support. The Cvetko Center also provides a patient education library containing books, pamphlets and computers to research their disease along with a listing of reputable cancer-related websites for reference.

Healing Environment—The healing environment concept uses nature, music, humor, art and relaxation techniques to help people manage pain and other effects of illness and contribute to their overall healing process. Healing environment sponsors a Relaxation television channel, featuring 24-hour programming with calming music and beautiful nature photography. Aromatherapy helps relieve stress, anxiety, nausea and other treatment side effects patients may experience. A music practitioner is available to play therapeutic music at the patient’s bedside to assist with the healing process. Ask your nurse for a referral for this free service. We also offer relaxation and journaling classes on a regular basis.

A copy of the Cvetko Center’s monthly calendar of events is available in waiting areas throughout Baylor Sammons Cancer Center at Dallas, by calling 214.820.2608 or online at BaylorHealth.com/Cvetko.

Financial ServicesBaylor Dallas has an experienced financial services team to educate and assist transplantation patients with their financial needs and insurance coordination. Professionals will help patients by providing information about insurance benefits, Medicare, Medicaid and other funding options.

Baylor T. Boone Pickens Cancer Hospital Baylor T. Boone Pickens Cancer Hospital is the first dedicated cancer hospital in North Texas and only the second in the state. This 96-bed, 175,000-square-foot facility has been specially designed to provide a place of healing, calming and spirituality for everyone involved in the cancer journey, according to Alan M. Miller, MD, PhD, chief of oncology for Baylor Health Care System and medical director of Baylor Charles A. Sammons Cancer Center at Dallas. A skybridge connects the inpatient hospital to the many outpatient services of Baylor Charles A. Sammons Cancer Center at Dallas.

Designed with modern, inviting, hotel-like décor, the hospital features a large selection of art in clinical areas and patient rooms. Each patient’s communication board is also a piece of art and a decorative magnet board gives them a space to personalize with get-well cards and photos from home.

The Oncology Evaluation and Treatment Center (OETC), located on the first floor of Baylor T. Boone Pickens Cancer Hospital, provides scheduled, urgent, non-emergency medical care from 4 p.m. to 7 a.m. Monday through Thursday and from 4 p.m. Friday to 7 a.m. Monday. This center was created to reduce the waiting time to receive care and for cancer patients in need of urgent, but not emergency care, and to help reduce their exposure to contagious diseases from others. Staff members are trained and knowledgeable about the specific issues, symptoms and side effects related to cancer and its treatments. Patients are referred to care at the OETC by their oncologist.

Services available to patients, their families and caregivers, include:

• Access to clinical trials at the Innovative Clinical Trials Center

• For families and caregivers, coffee from a coffee bar and meals from two dining areas, one of which includes a deli, gourmet grill and stations serving salad, pizza and pasta

• Meditation room• Two healing gardens• Large chapel• Teaching kitchen• Specialty boutique offering items to minimize

the visible effects of cancer therapy