block day- 3/7/12 homework: -design your own protein pathway project- due friday -protein...
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Block Day- 3/7/12
Homework:-Design your own protein pathway Project- due Friday-Protein Pathways/Protein Structure QUIZ- FRI- DID YOU MISS MONDAY’S CHECKUP?-
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Serotonin Pathway
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Homework CheckCircle your answer:• How does a MAO inhibitor treat depression?It decreases or increases the amount of serotonin.
Circle your answer:• If the AAAD enzyme doesn’t work, will there be higher or lower amounts of serotonin?
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Serotonin Pathway
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Serotonin Homework Answers:1. Less serotonin2. Higher serotonin3. Lower serotonin4. Blocks the enzyme MAO from working which
keeps serotonin available and decreases depression.
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Make an entry:
Entry 19: Fruit Fly Eye Color- 3/7/12Tape in picture and take notes
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2-amino-4-hydroxypterdine
(BLUE)
tetrahydroiopterin
biopterin(BLUE)
drosopterin(ORANGE)
sepiapterin(YELLOW)
isosepiapterin(YELLOW)
xanthopterin(GREEN-BLUE)
isoxanthopterin(VIOLET-BLUE)
Molecule A(colorless)
PTERIDINE PIGMENTS OMMOCHROMEPIGMENTS
Molecule B(colorless)
ommochrome pigment(BROWN)
31
5
4
6
2 9
7
8 10
In order to see pigments, they must be transported into specific areas of the eye cells. All the ommochrome and pteridine pigments use the same transport proteins (labeled as protein #10 on the network)
Color of fly is result of mixture of all pigments in network
Drosophila Eye Color Pigment Network
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Wild Type Brown
Scarlet White
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2-amino-4-hydroxypterdine
(BLUE)
tetrahydroiopterin
biopterin(BLUE)
drosopterin(ORANGE)
sepiapterin(YELLOW)
isosepiapterin(YELLOW)
xanthopterin(GREEN-BLUE)
isoxanthopterin(VIOLET-BLUE)
Molecule A(colorless)
PTERIDINE PIGMENTS OMMOCHROMEPIGMENTS
Molecule B(colorless)
ommochrome pigment(BROWN)
31
5
4
6
2 9
7
8 10
In order to see pigments, they must be transported into specific areas of the eye cells. All the ommochrome and pteridine pigments use the same transport proteins (labeled as protein #10 on the network)
Color of fly is result of mixture of all pigments in network
Wild Type (red-brown)= need all 10Brown= 9, 10 needed, must be missing #1
Red= need 1-8, 10- missing #9White= missing #10- no way color transported
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Metabolic Network ProjectCheck
box Requirement Score
Name of organism _____/1 Starting protein _____/1 3 proteins that determine trait, with
names _____/3 3 enzymes, with names _____/3
Drawing of organism with each trait_____/3
Explanation of what enzymes are needed for each trait _____/6
Creativity,clarity,neatness _____/3TOTAL _____/20
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Make an entry-Entry 20: Protein Quiz Review- 3/7/12
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Lactose
Glucose
Lactase
Galactose
Key:
Metabolites
Enzyme reactions
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Labrador (dog) pigmentation
Tyrosine Dopaquinone
Brown pigment
Black pigment
Yellow pigmenttyrosinase
TRP-2
TRP-1Boxes = metabolitesArrows = enzymes that change the metabolites
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Phenylalanine
Homogentisicacid
Tyrosine
Tyramine
Thyroxine
Hydroxy-phenylpyruvate
Dopa
Dopamine
NoradrenalineAdrenaline
Dopaquinone Melanin
Phenylpyruvate
Maleyl-acetoacetate
Prephenate
1
2 4
35
6