The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 296162 (BIOPOOL) and POCTEFA-INTERREG IV : REDTRANSFRONTERIZA DE INVESTIGACIÓN BIOMÉDICA DE LOS PIRINEOS (REFBIO)

BIOPOOL PROJECT: A new tool to search tumor samples for

research across Europe

(1)Cruces Universitary Hospital, Barakaldo, Spain; (2)Basque Biobank for Research/BIOEF, Barakaldo, Spain; (3)Erasmus MC Tissue Bank, Rotterdam, The Netherlands; (4)Tecnalia, Zamudio, Spain; (5)Araba Universitary Hospital, Vitoria-Gasteiz, Spain ; (6)Onkologikoa, Donostia, Spain ; (7)Galdakao-Usansolo Hospital; (8)Basurto Universitary Hospital; (9)eMedica, Donostia, Spain; (10) Pertimm, Asnières-sur-Seine, France

Mónica Saiz(1), Oihana Belar (2), Bas de Jong (3), Marcel Kap (3), Arantza Bereciartua (4), Rebeca Ruiz (5), Maria Amparo Viguri (5), Ricardo Rezola (6), Eduardo De Miguel (7), Alberto Saiz (7), Sara Fernandez (8), Ayman Gaafar (1), Blanca Catón (5), Javier Aguirre (5), Michael Doukas (3), Elena Muñoz (9), Fabienne Gandon (10), Peter Riegman (3), Roberto Bilbao (2).

CONCLUSION: BIOPOOL network, as a new concept for sample search and request, is now open to biobanks and pathology departments to

bring together, in a European scale, a research infrastructure that could help significantly to conduct research through the synergy of medical knowledge and technology.

www.biopoolproject.eu

Biobank 3

Biobank 4

Biobank n

Biobank 1

Biobank 2

Tumor surgically removed

Lung tumor processed to histological slide

Lung with tumor

Digital scanning of histological sections

Central server of Biobanks

Histological images

Associated Clinical data

Text and image based search queries of samples

at biobank network

3 STEPS SOLUTION

1.- Get access to the platform

2.-Perform query base on text or image

3.- Select and request the sample

PROBLEM: Searching human samples across Biobanks is a hard task due to the geographically dispersed biobanks distribution the diagnosis heterogeneity, language diversity and the lack of online accessible robust samples catalogues.

SOLUTION: A new web-based approach to provide a virtual view across multiple sites is desirable. The BIOPOOL consortium (www.biopoolproject.eu; 7PM EC; (GA296162)) has developed an innovative web search to look for samples located at different biobanks.

METHODOLOGY:

•Digital images from colon, breast and lung cancer were processed.

•11 pathologists participate actively with IT developers

OBTAINED RESULTS: Relevant visual descriptors were identified, coded and extracted automatically from the images in order to be included in the searching tool and retrieved later in the case it matches the query.

FINAL RESULT: A first prototype based on histological image data and associated clinical data of colon, breast and lung cancer has been developed.

http://www.biopoolproject.eu/http://www.google.es/url?sa=i&source=images&cd=&docid=966VZmiMczl4fM&tbnid=CLnlWlN2RCP7tM:&ved=0CAgQjRwwAA&url=http://www.nextel.es/2008/09/01/osakidetza-implanta-una-herramienta-de-desarrollo-profesional-realizada-por-nextel-s-a/&ei=7YCLUaqhCYfW7Qahs4Eg&psig=AFQjCNFzJ45Tl7CL7Kt_dgdAJ5u9KbDohg&ust=1368183405220473http://www.google.es/url?sa=i&rct=j&q=&esrc=s&frm=1&source=images&cd=&cad=rja&docid=4DWLEBQPPTlDEM&tbnid=bI10D9B5IH_phM:&ved=0CAUQjRw&url=http://mpilarmarquez.wordpress.com/2011/04/02/seminario-desarrollo-tecnologico-de-la-red-web-1-02-0-y3-0/&ei=AKArUpfVB-yb0wXhq4CoBg&bvm=bv.51773540,d.d2k&psig=AFQjCNHE6TKeNdaZQYBokijnj3vw-qk7vA&ust=1378676992090961