biomeditech over 250 scientists in world-class basic and translational research tissue engineering...
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BioMediTechA Source for
High Quality Research and Innovations
BioMediTech
Over 250 scientists in world-class basic and translational research• Tissue engineering and stem cell technology
• Biomaterials
• Sensor and actuator technologies
• Measurement and imaging technologies
• Biotechnology
• Immunology
• Cancer and mitochondrial research
• Systems biology
• Bioinformatics
• Computational methods in biomedicine
Joint institute of University of Tampere & Tampere University of Technology
Kauppi University Campus
Orig. http://www.pshp.fi/
BioMediTech• aims for excellence in
- education- basic research - translational research
• houses state-of-the-art laboratories and 200m2 GMP-level clean rooms
• EMEA approved GMP stem cell production unit
Aiming for Excellence
Example of Research Excellence
BioMediTech: world leader in stem cell based reconstructions of cranial bones
• 22 cases operated
• combination of biomaterials and stem cells differentiated from subcutaneous fat
2 months post op 28 months post op
• Nearly 20 M€ project funding for Human Spare parts program (2011-2015)• Development of tissue engineering products and supporting technologies • Tekes, Academy of Finland, Council of Tampere Region, EU
Tissue engineering at Regea
• Adult stem cells• Embryonic stem cells• iPSCs• Production in GMP and own
xenofree media
Cardiac, neural, opthalmological, soft and hard tissue applications
Adipose stem cells
Stem cells can be isolated from the patient’s own adipose tissue, differentiated in vitro and transplanted back into the host tissue rejections are avoided
S.Miettinen
Adipose stem cellsDifferentiate to....• Adipocytes• Osteocytes• Chondrocytes• Tendocytes
and also to• Neural cells?• (Cardio)myocytes?• Hepatocytes?• Epi/Endothelial cells?
Adapted from www.nationalacademies.org/stemcells, Wellen and Hotamisligil 2003, Hotamisligil 2006 by Bettina Lindroos
Adipose stem cells
Neurosurgery
Tampere University Hospital: Prof. Juha Öhman
Adipose stem cells and biomaterial
hASC, β- TCP