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    Program . ResearchEntrance Paper : Biological SciencesPaper Code : BC

    6

    INDIAN INSTITUTE OF SCIENCEBANGALORE - 560012

    f ime9.00A.M. TO 12.00 NOON

    \?. r/

    Day & DateSUNDAY, 25m APRIL 2010

    &&

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    GENERAL INSTRUCTIONS

    1. This question paper consists of 100 multiple choices questions and carriesa total of 100 marks, onemark for each question.

    2. Answers to all questions should be marked in the OMR sheet provided.3. For each question darken (fill) the appropriate bubble on theOMR sheet to

    indicate your answer.4. Use only HB pencils to darken the bubbleslanswers5. Darken only one bubble per question. If you mark more Ihan one bubble to

    answer a question, it will be evaluated as incorrect6 . If youwish to change your answer,please erase the existing markcompjetelybefore filling in the other bubble7. There is no negative marking for wrong answers.8. Candidates are required to f i l l in the required fields on the answers sheetattached.

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    18. I f the absolute temperaturedoubles, the velocityofmolecules in a gasincreasesby a faclorof

    19. Antigenic determinantsgenerated by the conformationofarnino acids presentin the variable regions ofirnmunoglobins are(A) allotypic(B) idiotypic(C) anli-idiotypic(D) heterovpic

    20. Chorionic gonadobopin hormone, synthesized in the placenta, plays animporiant role in the establishment and maintenanceofpregnancy in(A) cows

    (B) pigs(C) rodents(D) humans

    21. In the eye, which cells are responsible For visual detection in low lightconditions?

    (A) Rods

    (B) Cones

    (C) ON cells

    (D) Bipolar cells22. Whai is the sequence ofcell cycle progression in eukaryoiic cells?

    (A) G l toG2to S to M(B) Gl to M toG2 t o S(C) Gl toStoM toG2(D ) G1 toS toG2toM

    23. If all the 8 cysteine residues in a protein take part in making disulfide bonds,then the possible number of ways the four S-Sbonds can be forrned is(A) 8C2(B) 8P2

    (C) 7 x 5 ~ 3 ~ 1(0) ~ 3 x 2 ~ 1

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    29. Which one ofthe followinghas leasi solubi lity in water?(A) Lysozyme(B) CoHagenase(C) DNA polymerase(D) Rhodopsin

    30 . The structure equivalent to the frogs Spemann's organizcr in chicks is(A) Hensen's node(B) Notochord(C) Anterior visceral endodenn(D) Ventral mesoderm

    31. Which pair ofamino acids representsthc weakest interaction betweentheir side chains?(A) Ser ... Leu(B) Asn ... Thr(C) Tyr . . . Trp(D) Lys

    ...

    Phe

    32. A double reciprocal plot for an enzymatic reactionwiih a ping pong Bi Bimechanismlooks similar 10 the ploi obtained for(A) Competitive inhibition(B) Uncompetitive inhibition(C) Non competitive inhibition(D) Mixed non competitive inhibition

    33. Aspirin, used as a common analgesic, antipyretic and anti-inflammatoryagent,inhibits the synthesis ofwhich one ofthe following?(A) Arachidonic acid(B) Prostaglandins(C) Glucocorticoids(D) Histamine

    34.Which ofh e ollowing proteins are expressed on h e surface of help.erT cellsbut not on cytotoxicT ells?(A) CD2

    (B) CD3(C) CD4(D) CD8

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