biobanking in the philippines

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    BIOBANKINGTECHNOLOGY:

    Pros and Consof its use inDevelopingCountries likethe

    Philippines

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    ABSTRACTThe introduction of Biobanking Technology in

    Developing Countries in Southeast Asia like the Philippinesproved to be a success. To be eact ! the advent of its "irstCancer Research Center in St. #ukes $edical Center%S#$C& set up in '()* is at its early stages ho+ever! it isby no ,eans free fro, facing adversities and challenges.

    The "unding for the pro-ect +ould a,ass a fortune if not

    for the pre,ier health care provider like S#$C. nvestorsalike +ould be bene/cial to the continued lifespan of the

    In Partial Fulfllment o the Reuirement! inTe"hnolo#$ an% the La&

    Arellano 'ni(er!it$ )"hool o La&

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    )u0mitte% to: Att$1 Romulo L1 2e Grano 3r1

    )u0mitte% 0$: Lei%i A0e#ail C1 Ba$u%an

    *+,4.+-4+

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    Biobanking ndustry.

    #$TAT01SThe scope of this paper +ould be contained in the /rst

    type of Biobanking2 Biobanks for organs and tissues for

    therapy and transplantation. And that the Philippines is its

    ,ain focus.

    D3"1T01 0" T3R$S

    ,1 Bio0an5

    4 a place for biological sa,ples like hu,an tissue!

    blood! or D1A that ,ay be used especially for future

    ,edical research.

    *1 Biomar5er!

    4 al,ost any interaction re5ecting an interaction

    bet+een a biological syste, and a potential ha6ard!

    +hich ,ay be che,ical! physical! or biological. The

    ,easured response ,ay be functional and

    physiological! bioche,ical at the cellular level and

    ,olecular interaction

    41 2e(elo6e%

    4 a country having a standard of living or level of

    industrial production +ell belo+ that possible +ith

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    /nancial or technical aid7 a country that is not yet

    highly industriali6ed.

    8. 2e(elo6in#

    4 a nonindustriali6ed poor country that is seeking to

    develop its resources by industriali6ation

    BAC9:R0;1D

    What is a Biobank?4 n his Article published in the Philippine Star

    Dr. ,asa) de/ned it as a long term storage

    and conservation facility for biological

    speci,ens. t is created pri,arily to help

    researchers develop personali6ed ,edicine!

    innovative drugs and other therapies. t consists

    of the follo+ing2

    a. Biological ,aterials that are collected!

    1 Biobanking Toward Cancer (Imasa, 2015)

    www.pressreader.com

    http://www.pressreader.com/http://www.pressreader.com/
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    processed and dated for each collected sa,ple

    b. Database that contains the infor,ation and

    date of each collected sa,ple.

    4 0ver ti,e as ,ore speci,ens are collected

    and archived. Researchers analy6e and co,pare

    the actual ,olecular characteristics! and identity

    +hat +ent +rong +ith those cellsand tissues such

    that they beca,e diseased. 0nce they discover

    this! they can no+ for,ulate +ays of detecting

    the disease using that are kno+n as Bio,arkers.'

    Types of Biobanks

    There are ' broad categories in relation to type of

    sa,ples stored2

    ). Biobanks for organs and tissues for therapy and

    transplantation

    '. Biobanks for :enetics

    The "irst group has the collection and storage of

    organs! tissues! cells and products %D1A! proteins! etc.& for

    +hich therapy! diagnosis and research! is not a ne+

    practice since it has been carried out for ,any years in

    laboratories and hospitals. As a ,atter of fact a signi/cant

    a,ount of useful biological sa,ples of hu,an beings

    ca,e fro, ordinary health assistance acts and its stored

    in biobanks of organs and tissues for therapy and

    transplantation. n the Philippines this strated over a year

    2 www.ncbi.nlm.ni.go!

    http://www.ncbi.nlm.nih.gov/http://www.ncbi.nlm.nih.gov/http://www.ncbi.nlm.nih.gov/
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    ago at St. #ukes $edical Center.

    The second group! is the speci/c type of >? 1ational

    nstitutes of

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    the abnor,al cell! ,olecular of the deceased cell.

    Outcome5

    4 The end result is a treat,ent that is

    personali6ed! targeted innovative hopefully has

    fe+er side eects.

    1TR0D;CT01

    eveloped v! eveloping "ountry

    - n the for,er! biobanks have been

    established contributing to the current large 5u

    of cutting edge researches that have leapfrogged

    ne+ and diagnostic approaches and therapeutic

    5 Biobanking Toward Cancer (Imasa, 2015)

    www.pressreader.com

    http://www.pressreader.com/http://www.pressreader.com/
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    intervention. The treat,ent is ,ade ,ore

    personali6ed and in ad-unct +ith the needs of the

    patient. The latter ho+ever! its concept is a fairly

    ne+ /eld. t proved to be understandable due to

    the stringent /nancial and technical reuire,ents

    that cost a lot of ,oney and resources.E

    Biobanking in #outh $ast %sia

    China 9adoorie Biobank or C9B

    4 it +as set up to investigate the ,ain genetic and

    environ,ental causes of co,,on chronic diseases in

    the Chinese population

    & www.ncbi.nlm.ni.go!

    http://www.ncbi.nlm.nih.gov/http://www.ncbi.nlm.nih.gov/http://www.ncbi.nlm.nih.gov/
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    9orea Biobank Pro-ect %9BP&

    4 launched in '((? it is a net+ork bet+een the 1ational

    Biobank of 9orea and biobanks run by university aFliated

    general hospitals.

    Biobank apan Pro-ect

    4 it started in '((= and ended in '()'.

    4 it ai,s to investigate the relationship bet+een

    approi,ately =((!((( people as +ell as the eFcacy and

    side eects of the drugs used.

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    Biobanking in the &hilippines

    - The /rst hu,an cancer biobank in the

    country +as established on $ay '?! '()* at St.

    #ukes $edical Center %S#$C&. ts President! Dr.

    3dgardo Corte6 said that the idea for the pro-ect

    started in '()8. The ,ain thrust of setting up of a

    biobank is for patients to have a custo,i6ed

    treat,ent since analy6ing their sa,ples +ould

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    result to a ,ore personal approach to the

    ,edications to be used.

    The "irst

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    The vials are labeled +ith the patients na,e and are

    provided +ith a barcode

    A surgeon is seen getting the vials of the cancer patients

    for research.

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    Dr. 3dgardo Corte6 being intervie+ed about the

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    '

    'yth about the #('" Biobank

    4 At /rst even felt unease +ith the idea of a

    biobank since it is a fairly ne+ concept ,y

    preconception +as that having ,y sa,ples

    free6ed +ould entail loads of ,oney.

    ' www.cnnpilippines.comlies#*le20150&01+ig#ing#eBigCTeirs#$mancancerbiobankin-.#ml

    http://www.cnnphilippines.com/lifestyle/2015/06/01/Fighting-the-Big-C-The-first-human-cancer-biobank-in-PH.htmlhttp://www.cnnphilippines.com/lifestyle/2015/06/01/Fighting-the-Big-C-The-first-human-cancer-biobank-in-PH.html
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    The biobank in S#$C if free of charge it is still

    in its early stages. The fee for ,aintaining and

    constant funding of the fresh sa,ples is +hat

    see, a challenge to the biobank.

    PR0S and C01S

    PR0 C01can help cure cancer constant need of fundingpersonali6ed approach to

    evidenced4 based ,edicine

    traet,ent. Tailor /t to the

    patients needs.

    ,aintenance cost of the

    facility

    free of charge ,ulti4,illion dollar venture

    early stages of the research

    ne+ concept not kno+n to,any

    Storing ones tissue speci,en in a Biobank is the "utureof Cancer care. n their +ebiste St. #ukes $edical Centeras the pioneer of the countrys /rst Biobank on

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    C01C#;S01I R3C0$$31DAT01S

    The launching of Biobanks in the Philippines is still on

    its infancy stage and the constraints of the its +idespread

    infor,ation is not +ell4taken into concept by the "ilipinos.

    The reality is that in a Developing Country like the

    Philippines! the eposure of the general public and their

    a+areness to the idea of +hat a Biobank is taking a stall

    on their health. Technology like any other ,ust be utili6edin order to ,ai,i6e the potential of the society and not

    stunt its gro+th. f everybody has a facebook account +ith

    a readily available internet connection. The health sector

    should bo,bard the public of the ne+ and breakthrough

    develop,ents in the health industry. 1ot -ust the

    increassing nu,ber of health care BP0s providing -obs for

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    the +orking class but the need to raise a+areness. That in

    the country! +e have a biobank that could help cancer

    patients in their battle against the grueling disease. @hat

    is ,ore surprising is that it is free to store the speci,ens

    of the patients. @ith the future at bay! the scope of

    biobanking should be broadened to include the sper,

    banks in the country. Bearing the fact that +e do not have

    at present a Sper, Bank in the country! the closest +e

    can get is the n itro "ertili6ation! $aturation! ntrauterine

    nse,ination still at St. #ukes. The nearest neighboring

    sper, bank facility being in Singapore. $oreover!

    establishing such facility ai,s to provide single ,others

    +ho opt to conceive the chance of beco,ing a parent a

    choice and decision carefully planned to e,po+er +o,en

    in general.