bcm-95 curcumin - luckyvitamin · 2014-07-01 · ind j pharm sci. 2008:445-449. ... published human...

*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THESE PRODUCTS ARE NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

BCM-95® Curcumin The Safest, Most Successful Method to Enhance Curcumin Absorption• Enhanced Absorption and Retention• Up to 10 Times Greater Absorption Than Standard Curcumin• Results Verified in Published Human Clinical Studies

† Relief of occasional muscle pain associated with exercise or overuse

Published Human Crossover Study to Evaluate Absorption of BCM-95®1

The BCM-95® curcumin in Terry Naturally® products

is up to 10 times more absorbable than standard

95% curcumin.

Bioavailable BCM-95®

CurcuminStandard Curcumin

Absorption Comparison of Different Formulations of Curcumin

Time (hours)

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1. Antony B, Merina B, Iyer VS, Judy N, Lennertz K, Joyal S. A pilot cross-over study to evaluate human oral bioavailability of BCM-95®, a novel bioenhanced preparation of curcumin. Ind J Pharm Sci. 2008:445-449.


When Pain is the Problem, Curamin® is Your Answer*†

BCM-95® and BosPure® are registered trademarks of Dolcas-Biotech.

Curamin® Effective, Clinically Tested Ingredients!

BCM-95® Bioavailable Curcumin—Amazing Absorption

Curcumin modulates multiple inflammation pathways in the body. It is also a potent antioxidant. Curcumin is associated with immune system support, protection from oxidative stress, and most importantly for this formula, relief of pain due to exercise or overuse.* Curamin® features clinically-tested BCM-95®, which has up to 10 times the absorption and greater blood retention time at meaningful levels compared to standard curcumin extracts, so it can provide maximum benefits.

BosPure® Boswellia Extract—A Better Form of Boswellia

The clinically-tested BosPure® standardized boswellia (Boswellia serrata) extract in Curamin® helps modulate the activity of 5-LOX (lipoxygenase).* BosPure® is filtered to reduce β-boswellic acid, which can potentially promote, rather than balance, inflammation—to just 5% or less, compared to up to 20% in plain boswellia. Plus, it provides more than 10% acetyl-11-keto-β-boswellic acid—known as AKBA—which is considered one of boswellia’s most beneficial compounds, boosting the benefits of the extract even further. This is up to ten times more than plain boswellia!*

DLPA—Supporting The Brain’s Response to Pain*The amino acid DLPA (DL-phenylalanine) contains two forms, the “D” and the “L”. The “D” form inhibits the breakdown of compounds called enkephalins. Enkephalins are in the same family as endorphins, and are associated with positive mood. They have also been shown to relieve occasional muscle pain due to exercise or overuse.* The “L” form improves mood-elevating chemicals in the brain, such as dopamine, epinephrine, and norepinephrine—an important and often overlooked factor when dealing with pain.*†

Nattokinase—Support for healthy circulation*Nattokinase is an enzyme extract of the fermented food, natto. This enzyme helps promote blood flow, aiding the other ingredients in the formula to reach all areas of the body.* It also helps support balanced fibrinogen levels in the body.* This is one of the crucial factors in dealing with pain due to exercise or overuse: excess fibrinogen levels are common in post-exercise muscle pain and occasional muscle strain, and may contribute to muscle stiffness.*

Got Pain?*† Get Curamin® !Curamin® is the complete formula for dealing with pain naturally.*† It can make a life-changing difference.

Also, look for:

Curamin® Extra-Strength Stronger, Safe & Effective Pain Relief!*†

Curamin® Extra-Strength provides the same strong ingredients found in Curamin, including the amazing curcumin extract BCM-95®, but in a tablet that provides even higher levels of key ingredients for pain relief in each dose.*†


How Do You Feel?

While 4 out of 10 people experience occasional pain, 60% of those surveyed thought it was “just something you have to live with.” In fact, 28% of respondents to this same survey believe there is no solution for their personal pain concerns. But is this really true? Add to these findings the fact that some athletes consider severe muscle pain a necessary part of physical fitness, and you might wonder if our perceptions of pain are correct or even really healthy after all. Fortunately, there are natural ingredients, including BCM-95® curcumin that can make a big difference.

“Pain in America.” Gallup survey, April 6, 2000. PR Newswire Association, LLC. Available at: http://www.thefreelibrary.com/_/print/PrintArticle.aspx?id=61798446. Accessed: December 16, 2011.

Pain Relief *†


BCM-95® is a registered trademark of Dolcas-Biotech.

Published Human Crossover Study to Evaluate Absorption of BCM-95®1

The BCM-95® curcumin in Terry Naturally® products

is up to 10 times more absorbable than standard

95% curcumin.

The BCM-95® Difference: Curcumin Made Effective, Safe, and Absorbable

Standard curcumin is poorly absorbed. Therefore, clinical trials have used increasingly larger dosages (up to 10-12 grams daily) in order to get even a small amount into the bloodstream. While no toxicity is associated with curcumin, even at these very high dosage levels, cost, comfort and compliance can be a tough issue to resolve for many people. Research has also focused on how to improve the absorption of curcumin by adding lecithin or more problematically, piperine, which can interact negatively with many prescription medications.

BCM-95® is different. It has been the most successful by micronizing curcumin and adding turmeric essential oils to enhance absorption naturally. In fact, comparison testing shows that this formula has up to 10 times better absorption and greater blood retention time at more significant levels than standard curcumin extracts!1

The Terry Naturally® suite of products from EuroPharma®, built around BCM-95®, address a variety of health concerns. This is great news for anyone interested in supporting their health with a strong, proven botanical ingredient.

Proven Absorption

• Ethically Harvested: The turmeric root used to create BCM-95® is grown in North East India, in the state of Assam, where optimal growing conditions are found. It is grown without the use of pesticides or chemicals.

Only natural fertilizers are applied. After harvesting the turmeric, the leaves are burned and tilled back into the soil. This is time-consuming work—done almost entirely by hand, and the crops are carefully—and sustainably—tended.

• Vigorously Tested: Incoming raw material is regularly analyzed for contaminants (including heavy metals and solvents), in addition to standardization parameters including curcumin content, moisture, and other factors. After extraction, micronization, and blending with turmeric essential oils, the potency of the curcumin is again verified.

• Committed to Good Works: EuroPharma® is in the business of improving lives, and that includes the people who plant, tend, and harvest the turmeric crop for BCM-95®. They are independent local farmers, who sell their crops through a cooperative society that ensures they are paid reasonable and competitive prices.

Turmeric

Common Problems with Standard Turmeric/Curcumin—Resolved with BCM-95® ! Standard turmeric/curcumin extracts in the past have promised much, but tended to deliver little. There are a few reasons for this: • Only about 2-5% of the spice turmeric is actually curcumin • Curcumin extracts are very poorly absorbed • Retention time at meaningful levels in the blood is short, which limits its ability to have sustained impact • Combining with black pepper to increase absorption significantly increases the risk of adverse interactions with commonly prescribed medications

But BCM-95® changes this—it provides a truly safe and effective option for those who want to experience the time-tested benefits of curcumin from turmeric.


Bioavailable BCM-95®

CurcuminStandard Curcumin

Absorption Comparison of Different Formulations of Curcumin

Time (hours)

0 1 2 3 4 5 6 7 8 9

350

300

250

200

150

100

50

0

1. Antony B, Merina B, Iyer VS, Judy N, Lennertz K, Joyal S. A pilot cross-over study to evaluate human oral bioavailability of BCM-95®, a novel bioenhanced preparation of curcumin. Ind J Pharm Sci. 2008:445-449.

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CuraMed® A Healthy Inflammation Response*

The premise behind CuraMed® is simple: it delivers a better form of curcumin—high absorption BCM-95® —at levels that make a difference. CuraMed truly delivers, without the risks of piperine or dubious promise of a synthetic form of a single curcuminoid. That translates to superior natural support for a healthy inflammation response, better resistance to free radicals, and a healthy immune and cardiovascular system.*

Bos-Cur™ provides the clinically proven power of BosPure® boswellia and BCM-95® curcumin to modulate the 5-LOX enzyme (5-lipoxygenase) and support a healthy inflammation response.

That means strong support for: • Healthy digestion and bowel function* • Respiratory health and inflammation response*

Two Amazing Ingredients—One Powerhouse Supplement! Boswellia provides excellent natural support for a healthy inflammation response. Additionally, patented

Bos-Cur™ Supports a Healthy Inflammation Response with Boswellia and Curcumin*

** Based on independent lab analysis per 100 grams BCM-95®

Provides clinically studied BCM-95® for superior absorption & retention: • Protects from oxidative stress • Has an amazing antioxidant ORAC value: >1,000,000** • Supports cellular health and immune system modulation* • Available in 375 mg or 750 mg softgels

BosPure® boswellia reduces those compounds in boswellia that can interfere with beneficial activity, such as β-boswellic acid, to 5% or less, and provides standardized levels of more than 10% acetyl-11-keto-β-boswellic acid (AKBA) which greatly increases the effectiveness of the extract. Because boswellia can help modulate the activity of 5-LOX (lipoxygenase), clinically tested BosPure® is a must in any natural approach to balancing the body’s inflammation response.*

Bos-Cur™ also features BCM-95® curcumin, a perfect partner ingredient to BosPure® boswellia, to help support a healthy inflammation response throughout the body.*

The World’s Best Curcumin!

Lung & Intestinal Health*



Curamin® PM Sleep Your Pain Away*†

Many people don’t get the sleep they need, and many times, occasional pain is the reason.*† When nighttime pain is the problem, Curamin® PM is the answer.*† Get a good night’s sleep with powerful, effective and clinically proven ingredients.

Curamin® PM combines the BCM-95® curcumin, BosPure® boswellia, and DLPA (DL-phenylalanine) found in our original award-winning Curamin® with melatonin and bioavailable vitamin B6 (P-5-P) to help relieve pain and support healthy sleep.*†

Melatonin is known for supporting healthy sleep by helping “set” the circadian rhythms—the natural timekeeping and sleep cycle—and is especially important for travelers, shift workers, or anyone with occasional sleeplessness.*

Vitamin B6 as Pyridoxal-5-Phosphate (P-5-P) is important for mental well-being. Low levels of vitamin B6 may be a factor in serotonin production and other reactions in the body that determine mood and nervous system function. Randomized, double-blind, placebo controlled clinical studies have also shown that vitamin B6 can help relieve stress associated with premenstrual syndrome. By supplementing with the pyridoxal-5-phosphate (P-5-P) bioactive form, the body doesn’t need to convert the vitamin B6, so it works for every body.

Nighttime relief naturally:†

• No morning drowsiness • Can use each night, or just when needed

Nighttime Pain Relief *†

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Arthocin® is a proprietary formula that promotes joint and cartilage health by safely balancing COX-2 and 5-LOX enzymes and major signaling and biological pathways.*

Arthocin combines high-absorption BCM-95® curcumin and clinically-tested BosPure® boswellia extract with two amazing botanicals: Devil’s Claw and Indian Gooseberry—that help modulate the activity of COX-2—and more!* In fact, these ingredients work together to: • Support healthy cartilage structure • Modulate formation of leukotrienes • Improve joint comfort and mobility in joints and back • Devil’s claw is shown to increase hyaluronic acid synthesis in chondrocytes by up to 41%, which can support healthy joint lubrication*

Combine Arthocin® and Curamin® for more significant support.

Arthocin®

Joint and Back Health, Flexibility and Comfort*

Devil’s Claw (Harpagophytum procumbens) is a low-growing perennial found only in southern Africa. The extract used in Arthocin is standardized at 20% harpagosides—a key component for the best benefits—where most other products are either unstandardized or only standardized for 2% of harpagosides. It has been found to modulate expression of COX-2 by up to 31% and increase hyaluronic acid synthesis in chondrocytes, which can support healthy joint lubrication, by up to 41%.*

Indian gooseberry (Emblica officinalis) is also known as Amla, and has a long history of use in Ayurvedic medicine. It is a potent antioxidant and has been shown to support healthy collagen and cartilage formation.*

These ingredients work together to support healthy cartilage structure, and improve comfort and flexibility, with no stomach irritation.*

Healthy Knees & Joints™ provides the clinically- proven combination of BCM-95® curcumin and BosPure® boswellia that delivers comfort to the joints—especially the knees—by supporting healthy joint structure and function, including the cushioning cartilage between the joints.*

In a clinical study, this same BCM-95® and BosPure® combination supported healthy knee structure and mobility when compared to a conventional approach. In fact, it outperformed it! At the end of the study, 93% of the individuals in the BCM-95/BosPure group could walk more than 1000 meters vs. 86% of the conventional group. And, 93% of the herbal group reported improvement in comfort vs. 79% of the comparison group.

Healthy Knees & Joints™ combines these ingredients with vitamin D3 and fructoborate for enhanced support of the bone structure around the knees and

Healthy Knees & Joints™ Supports Knee & Joint Flexibility, and Mobility*

joints. These are important additions, because most people don’t get the vitamin D they need through diet or exposure to sunlight. This valuable nutrient helps support many functions in the body, including bone, joint, and cartilage structure.*

Fructoborate is a unique form of borate found naturally in fruits and vegetables that provides targeted support to joint structure. It has been clinically shown to boost the serum level of vitamin D3.*

Healthy Knees & Joints™ is the right choice for an active life, and can be combined with Curamin® for even stronger benefits!

Joint & Back Support*

Knee & Joint Strength*

©2012_08_C114

Back




Antony B, Merina B, Iyer VS, Judy N, Lennertz K, Joyal S. A pilot cross-over study to evaluate human oral bioavailability of BCM-95®, a novel bioenhanced preparation of curcumin. Ind J Pharm Sci. 2008:445-449.

Benny B, Antony B. Bioavailability of Biocurcumax (BCM-95). Spice India. September, 2006:11-15.

B. Antony, R. Kizhakkedath, M. Benny, B. Kuruvilla. Clinical Evaluation of an Herbal Formulation in the Management of Knee Osteoarthritis. Poster presentation. Presented at the Osteoarthritis Research Symposium Internationale (OARSI) Annual World Congress on Osteoarthritis, September 15-18, 2011.San Diego, CA.

Baum L, Lam CW, et al. Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease. J Clin Psychopharmacol. 2008 Feb;28(1):110-3.

More studies available upon request.

EuroPharma, Inc. | 955 Challenger Drive | Green Bay, WI 54311 | 877-807-2731

BCM-95® Curcumin: Safe, Proven, Effective:

BCM-95® curcumin, green tea extract, and resveratrol are powerful defenders against free-radical damage and support the body’s healthy inflammation response. Combined, they provide a strong cellular defense, protecting against oxidative damage and accelerated aging and preserving healthy DNA.*

• Highly absorbable, clinically-studied BCM-95® curcumin for maximum absorption and retention. • Caffeine free Green tea extract standardized for the very compounds that provide multiple health benefits.* • Resveratrol to support healthy cell growth, healthy cholesterol levels already within normal limits, cardiovascular function, and healthy aging.*

Curacel™ Sustains Healthy Cell Growth, Especially in Breast and Prostate Tissue*

Super Antioxidant/Healthy Aging Support*

Dyflaminol™ Healthy Inflammation Response*

Dyflaminol™ harnesses the natural power of BCM-95® curcumin, BosPure® boswellia, and combines it with ginger, which is known for its ability to support a healthy inflammation response of both the 5-LOX (lipoxygenase) and the COX-2 (cyclooxygenase) pathways, and DLPA, an amino acid which acts in a unique way to promote pain relief.*†

• Three powerful botanical ingredients, plus DLPA for mood support • Clinically-studied BCM-95® and BosPure® • Traditionally-used ginger for a healthy inflammation response of both the 5-LOX and the COX-2 pathways.*

Focused Inflammation Balance*

Mental Advantage™ combines two plant oils— rosemary and sage—with BCM-95® curcumin and Vitamin D. Together, these ingredients have protective antioxidant effects for brain cells, as well as supporting memory and mental function.*

• Includes powerful BCM-95® curcumin • Shields the brain from free radical damage • Provides the antioxidant power of rosemary, the “herb of remembrance,” and sage oil • Vitamin D to enhance brain effectiveness*

Powerful Brain Support* Mental Advantage™ Supports Short-Term Memory, Concentration and Cognitive Function*

bcm-95 curcumin - luckyvitamin · 2014-07-01 · ind j pharm sci. 2008:445-449. ... published human...

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