Medihoney® Barrier Cream helps maintain the skin’s bar-rier properties and maintain skin moisture and pH.

• Suitableforwetareas*• HelpsmaintainpHoftheskin

• Contains30%Medihoney®AntibacterialHoney

*Medihoney® Barrier Cream can be applied to intact and at-riskskintoprovideprotectionfrombodyfluidsand moisture.Itcanbeappliedaroundwoundsandunderskinfolds,wounddressingsandincontinencepadswherea protectivebarrierwillhelppreventskinbreakdown.

INDICATIONS FOR USE• Protectsat-riskskinfrombreakdownassociatedwith incontinence and can be used under incontinence pads

• Canbeusedaroundwoundedgestoprotecttheskin fromirritationorbreakdowncausedbywoundexudate

• Helpsprotecttheskinfromdamagecausedby frictionorshear

• Helpspreventmaceration

• Helpspreventexcoriation

• HelpsmaintaintheskinpH

• Helpspreventdamagetoskincausedbyfrequent handwashing.

SPECIALLY FORMULATEDMedihoney®BarrierCreamisspeciallyformulatedwith arangeofnaturalingredientsand:

• NOAddedcolourorfragrance

• NOLanolin

• NOParabens

• NOSteroids

• NOMineralOils

DIRECTIONS FOR USEApplytoclean,dryskinthreetimesadayorasrequired.Reapplyafterbathingorateachdressingchange.Suitableforuseonchildren.

Barrier Cream

Derma Sciences Europe Ltd.Suite2 1A Park StreetMaidenhead SL6 1SL U.K.Tel: +44 (0) 1628 625 916 Fax: +44 (0) 1628 671 112

ITEM# PRODUCT NAME PIP CODE NHS CODE

582 Medihoney® 338-7644 ELY289 Barrier Cream 50g

800 Medihoney® 369-1276 ELY374 Barrier Cream Sachet 2g

Medihoney® is a trademark of Medihoney Pty Ltd. and licensed by Comvita New Zealand Ltd.

Derma Sciences Europe Ltd.Suite2 1A Park StreetMaidenhead SL6 1SL U.K.Tel: +44 (0) 1628 625 916 Fax: +44 (0) 1628 671 112

THE SKINNormalskinhasanaturallyacidicprotectivemantle.Theacidmantlehelpstohydratetheskinbyprotectingitfromdryingandfromharmfulbacteria2.Skinailmentssuchaseczema and dermatitis are linked to a disrupted acid mantlewithsubsequentcolonisationbybacteriasuchas.TheuseofMedihoney®BarrierCreamhelpsmaintaintheskin’s protective pH. In vitro studieshaveshowntobeoneofthemostsensitivebac-teriatoMedihoney®AntibacterialHoney™.Medihoney® BarrierCreamcontains30% Medihoney®AntibacterialHoney™whichisproventobeef-fectiveagainstarangeofmicroorganisms.

MEDIHONEY® ANTIBACTERIAL HONEYMedihoney®woundcareandskincareproductscontainmedicalgradeAntibacterialHoney.Advancedbiomedicalresearchhasidentifiedspecificplantsthatproducehoneywithexceptionalantibacterialactivity.Theantibacterialactivityofhoneydiffersaccordingtotheplantspeciesandmayvaryenormouslywithinanyonespecies.Medihoney® AntibacterialHoney™isastandardisedantibacterialhoney,predominantlysp.selectedforitsbroadrangeofantibac-terial actions.

In2007,thejournalWoundsfeaturedanarticlethatevaluated theinvitroactivityofMedihoney®AntibacterialHoney™ againstachallengesetof127clinicalisolateswithmultipleantibioticresistance.ThestudyshowedthattheMedihoney® AntibacterialHoney™waseffectiveatinhibitingthesebacteria irrespectiveoftheirlevelofantibioticresistance.

• Particularlyeffectiveagainstand MRSAdowntoa4%dilution1.

References:

1.GeorgeNM&CuttingKF2007.AntibacterialHoney(Medihoney®):in-vitroActivityAgainstClinicalIsolatesofMRSA,VRE,andOtherMultiresistantGram-negativeOrganismsIncluding Pseudomonas aeroginosa. J Wounds;19(9):231-236

2.TaskapanMO&KumarP2000.Roleofstaphylococcalsuperantigensinatopicdermatitis:fromcolonisationtoinflammation.Annals of Allergy, Asthma, & Immunology;84(1):3-10

NORMAL SKIN

Basal cells of stratum germinativum

Polyhedral cells of stratum spinosum

Acid mantle

Bacteria colonisation Desmosomes

- stratumgranulosum

Trans-epidermalwater loss

MIC OF 127 DRUG-RESISTANT CLINICAL ISOLATES (1990-2004)Narelle George, Qld Health Pathology and Scientifi c Services, Royal Brisbane HospitalBacteria Minimum Inhibitory Concentration (MIC).

Concentration of Medihoney® (%)Antibacterial Honey™

MRSA / nm* MRSA

ESBL

VRE

Acinetobacter

Pseudomonas aeruginosa

0% 2% 4% 6% 8% 10% 12% 14% 16%

Barrier Cream

Medihoney® is a trademark of Medihoney Pty Ltd. and licensed by Comvita New Zealand Ltd.