Pressure BioSciences, Inc.

State-of-the-Art High Pressure Generator

for Multiple Laboratory Applications

Discovery Starts with Sample PreparationTM

The Barocycler HUB440 is Capable of Creating and Controlling Hydrostatic Pressure from 35 Bar up to 4,000 Bar (~500 psi to ~58,000 psi)

The Barocycler HUB440 is the Hub that Powers Your Laboratory’s High Pressure Needs

Barocycler HUB440TM

Pressure Generator

Pressure is a primary thermodynamic parameter of central importance in molecular conformation, chemical equilibrium, reaction kinetics, and molecular interactions.

The Barocycler HUB440 is capable of creating and controlling hydrostatic pressure from 35 Bar (~500 psi) up to 4,000 Bar (~58,000 psi). The Barocycler HUB440 is the first portable, automated, bench-top, high pressure generator for the life sciences laboratory.

Barocycler HUB440

High Pressure Generator

State-of-the-Art High Pressure Equipment for a Wide Variety of Laboratory Applications

• EPR/NMR spectroscopy • Deep sea biology • Thermodynamic experiments • Material Science • High pressure freezing • Solvent extraction • Chemical reaction kinetics • Pathogen inactivation • Control of enzymatic activity

• UPLC • Chemical synthesis • Protein aggregation • Vaccine development • Protein conformation studies • Compressibility measurements • High pressure food science • Spore germination studies • Cell lysis

• Maximum Operating Pressure 4,000 Bar (~58,000 psi)

• Minimum Operating Pressure 35 Bar (~ 500 psi)

• Intensifier Displacement : 0.22 in³ (3.6 mL)

• Compact and Portable (17” X 12” X 9”, 55 lbs)

• Built for Expansion

• Manual or Analog Signal External Control

• Optional Data Acquisition and Control System with PBI software

• Rapid Pressure Change (full pressure in less than 2 seconds)

• Air Pressure and 24VDC power source required (suitable for mobile field use).

AC adapter is supplied.

Features

Barocycler HUB440

High Pressure Generator

1. Open frame design for easy reconfiguration 2. Repositionable carry handles 3. Luer-Lock syringe injection port for system fluid 4. Rear connector for external control 5. Mating connector cable provided 6. 9/16”-18 standard ¼” tubing high pressure port 7. Intensifier air pressure gauge 8. System error indicator light 9. Control pressure LED display 10. Inlet pressure gauge 11. Valve position indicator 12. Input power indicator light 13. Recessed manual control panel

Barocycler HUB440

High Pressure Generator

The HUB440 is the first automated, bench-top, high pressure generator for the life sciences laboratory. The HUB440 has an optional USB-powered computer interface* capable of complex data acquisition and control. A user can easily develop custom LabVIEW™ programs to interface with spectroscopy, HPLC, and other analytical instrumentation.

A broad selection of custom options is available from Pressure BioSciences, your trusted partner in high pressure bioscience.

*Note: Computer Not Supplied

Optional HUB Controls Software Specifications

HUB Controls v.1.01 User Interface:

Developed using National Instruments LabView Modes of operation:

• Barocycler Emulator

• Barostat: Pressure hold with transducer feedback

• Wave Generator: Sine, Triangular, Square Wave, Saw Tooth,

• Arbitrary table lookup

• Manual control mode Data capture from up to 2 pressure transducers Temperature logging – up to 2 channels, thermocouples Type K, T, S Data acquisition – up to 12 customizable channels available Data Logging capability Data import /export – interface with Microsoft Excel® file I/O Unlimited potential for instrument control and data acquisition

Also included are Sine Wave, Square Wave, Triangular Wave, Saw Tooth profiles, manual control options, analog and digital external triggering, and watchdog timer. Custom integration services are available upon request.

Custom Arbitrary Time Table

PCT Emulator

For additional information, please contact: info@pressurebiosciences.com

14 Norfolk Avenue South Easton, MA 02375 508-230-1828 (T) 508-230-1829 (F) www.pressurebiosciences.com

V1.081611