barium product portfolio update - rsna 2013rsna2013.rsna.org/files/639/barium product portfolio...

Interventional Diagnostic Radiology

CT Suite

Barium Product Portfolio Update

Committed to Science, Committed to You.™

Bracco has made a long-term commitment to your imaging needs. As part of that, we have

streamlined our Bracco/E-Z-EM portfolio of barium products, discontinuing some of our

existing barium products or some of the barium product presentations. The streamlining of

our product offerings is the result of a very careful process, during which we have analyzed

potential redundancies and have ensured that specific barium products will continue to be

available for the different gastrointestinal segments and imaging modalities using barium.

In optimizing our barium portfolio, we are working with the FDA and with experts in the

field of abdominal radiology to ensure that we continue to meet the needs of the radiology

community and continuity of patient care.

We have ensured that products recommended as a substitute for those being discontinued

provide comparable or superior results, often at the same price or lower. Our sales

representatives have gone through training on the changes and can help find a substitute

for the barium products you and your customers have relied on. A complete list of

discontinued products is itemized on the next page. We have also included a new

complete Bracco Barium Product SKU list enclosed in the pocket of this brochure.

We’ve Streamlined Our Barium Products in Order to Serve You Better

Fluoroscopy Products

Double Contrast Upper GI E-Z-HD™ 12 oz, 25 lb. Pail Maxibar™ 120 mL Digibar™ 232 gSingle Contrast Upper GI/Small Bowel E-Z-Paque® 6.2 oz, 1200 g, 10 kg Pail Liquid E-Z-Paque® 12 oz, 1900 mL Ultra-R® 6 oz Sensatrast™ 4.2 ozSmall Bowel Entero Vu™ (13% w/v After Reconstitution), 100 g Packets Liquid Entero Vu™ (13% w/v, 12% w/w), 600 mL Entero Vu™ (24% w/v, 20% w/w), 600 mL Entero-H® 1900 mLSingle Contrast Barium Enema Polibar® ACB 14 oz, 16 ozDouble Contrast Barium Enema Liquid Polibar® 1900 mL Liquid Polibar Plus® 1900 mL E-Z-Dose™ with Liquid Polibar Plus® 650 mLEsophageal E-Z-Paste®

E-Z-Disk™

Modified Barium Swallow Studies Varibar® Thin Liquid Varibar® Nectar Varibar® Thin Honey Varibar® Honey Varibar® Pudding

CT Products

Smoothie READI-CAT® 2 Apple 450 mL Banana 250 mL, 450 mL Berry 450 mL Creamy Vanilla 250 mL, 450 mL Mochaccino 450 mLREADI-CAT® 2 READI-CAT® 2 450 mL, 900 mL, 1900 mLREADI-CAT® READI-CAT® 450 mL, 900 mL, 1900 mLE-Z-Cat® Dry E-Z-Cat® ConcentrateEsopho-Cat®

VoLumen® (Neutral Contrast)Tagitol™ V (CTC)

Only the products indicated in red below are being discontinued. See the charts inside for appropriate substitution product ordering information.

®/™ indicates trademark of E-Z-EM, Inc. or E-Z-EM Company, Inc.

Fluoroscopy: Discontinued Product Bracco #

E-Z-EM # Unit Substitution Product Bracco

#E-Z-EM # Unit Comments

Double Contrast Upper GI

E-Z-HD™ Barium Sulfate for Suspension(98% w/w), 25 lb. Pail

901801 765 1 � E-Z-HD™ Barium Sulfate for Suspension (98% w/w), 340 g (12 oz)

901702 764 24

The discontinuation process is limited to the 25 lb. pail presentation. The 340 g (12 oz) bottle will continue to be available on the market.

Maxibar™ Barium Sulfate Suspension (210% w/v, 80% w/w), 120 mL

902701 L150 24 � E-Z-HD™ Barium Sulfate for Suspension (98% w/w), 340 g (12 oz)

901702 764 24E-Z-HD™ is a high density, low viscosity, barium sulfate powder for oral administration. It is supplied in 340 g bottles and yields 135 mL of 250% w/v suspension, after reconstitution as directed with 65 mL of water. Typical adult dose is 65-135 mL of suspension.

Digibar™ 190 Barium Sulfate for Suspension (190% w/v When Constituted), 232 g


901702 764 24

Single Contrast Upper GI/Small Bowel

E-Z-Paque® Barium Sulfate for Suspension (96% w/w), 10 kg Pail

903001 747 1 � Any E-Z-Paque® Product, Powder or Liquid See Product List Enclosed

The discontinuation process is limited to the 10 kg pail presentation. The 6.2 oz bottle and the 1200 g jug will continue to be available on the market.

Ultra-R® Barium Sulfate for Suspension (95% w/w), 6 oz (170 g)


E-Z-Paque® (96% w/w) offers flexible dosing from 54%–114% w/v (38%-60% w/w).

Liquid E-Z-Paque® is a ready-to-use suspension of 60% w/v.

Sensatrast™ Barium Sulfate USP, Ph. Eur 100%, 4.2 oz (120 g)

903002 788 24 �There is almost no clinical use reported for Sensatrast™. Alternative diagnostic non-barium-based procedures, including endoscopy, CT and MRI, could be taken into consideration for patients with a history of severe allergic reactions in whom the administration of barium product is not recommended.

Small Bowel

Entero Vu™ Barium Sulfate for Suspension (13% w/v After Reconstitution), 100 g Pouches

901401 754 12 � Entero Vu™ Barium Sulfate Suspension (24% w/v, 20% w/w), 600 mL

901407 L145 12Entero Vu™ (24% w/v, 20% w/w) is a ready-to-use suspension which, similarly to Entero Vu™ and Liquid Entero Vu™, contains barium suspended in methylcellulose for small bowel examinations but at a higher barium sulfate concentration.

Liquid Entero Vu™ Barium Sulfate Suspension (13% w/v, 12% w/w), 600 mL

901406 L140 12 � Entero Vu ™ Barium Sulfate Suspension (24% w/v, 20% w/w), 600 mL

901407 L145 12

Single Contrast Barium Enema

Polibar® ACB Barium Sulfate (96% w/w), Prefilled Disposable Barium Enema Kit, 16 oz (454 g)

900506 AP16 24 �Polibar® ACB Barium Sulfate (96% w/w), Prefilled Disposable Barium Enema Kit, 14 oz (397 g)

900504 AP14 24

The discontinuation process is limited to the 16 oz Polibar® ACB in Snap-Cap Enema Bag. The 14 oz presentation will continue to be available on the market.

Fluoroscopy: Discontinued Product Bracco #



Double Contrast Upper GI

E-Z-HD™ Barium Sulfate for Suspension(98% w/w), 25 lb. Pail


901702 764 24

The discontinuation process is limited to the 25 lb. pail presentation. The 340 g (12 oz) bottle will continue to be available on the market.

Maxibar™ Barium Sulfate Suspension (210% w/v, 80% w/w), 120 mL

902701 L150 24 � E-Z-HD™ Barium Sulfate for Suspension (98% w/w), 340 g (12 oz)

901702 764 24E-Z-HD™ is a high density, low viscosity, barium sulfate powder for oral administration. It is supplied in 340 g bottles and yields 135 mL of 250% w/v suspension, after reconstitution as directed with 65 mL of water. Typical adult dose is 65-135 mL of suspension.

Digibar™ 190 Barium Sulfate for Suspension (190% w/v When Constituted), 232 g


901702 764 24

Single Contrast Upper GI/Small Bowel

E-Z-Paque® Barium Sulfate for Suspension (96% w/w), 10 kg Pail


The discontinuation process is limited to the 10 kg pail presentation. The 6.2 oz bottle and the 1200 g jug will continue to be available on the market.

Ultra-R® Barium Sulfate for Suspension (95% w/w), 6 oz (170 g)


E-Z-Paque® (96% w/w) offers flexible dosing from 54%–114% w/v (38%-60% w/w).

Liquid E-Z-Paque® is a ready-to-use suspension of 60% w/v.

Sensatrast™ Barium Sulfate USP, Ph. Eur 100%, 4.2 oz (120 g)

903002 788 24 �There is almost no clinical use reported for Sensatrast™. Alternative diagnostic non-barium-based procedures, including endoscopy, CT and MRI, could be taken into consideration for patients with a history of severe allergic reactions in whom the administration of barium product is not recommended.

Small Bowel

Entero Vu™ Barium Sulfate for Suspension (13% w/v After Reconstitution), 100 g Pouches

901401 754 12 � Entero Vu™ Barium Sulfate Suspension (24% w/v, 20% w/w), 600 mL

901407 L145 12Entero Vu™ (24% w/v, 20% w/w) is a ready-to-use suspension which, similarly to Entero Vu™ and Liquid Entero Vu™, contains barium suspended in methylcellulose for small bowel examinations but at a higher barium sulfate concentration.

Liquid Entero Vu™ Barium Sulfate Suspension (13% w/v, 12% w/w), 600 mL

901406 L140 12 � Entero Vu ™ Barium Sulfate Suspension (24% w/v, 20% w/w), 600 mL

901407 L145 12

Single Contrast Barium Enema

Polibar® ACB Barium Sulfate (96% w/w), Prefilled Disposable Barium Enema Kit, 16 oz (454 g)

900506 AP16 24 �Polibar® ACB Barium Sulfate (96% w/w), Prefilled Disposable Barium Enema Kit, 14 oz (397 g)

900504 AP14 24

The discontinuation process is limited to the 16 oz Polibar® ACB in Snap-Cap Enema Bag. The 14 oz presentation will continue to be available on the market.

CT: Discontinued Product Bracco #



Apple Smoothie READI-CAT® 2 Barium Sulfate Suspension (2.1% w/v, 2.0% w/w), 450 mL

450303 7350 24 �Any other Smoothie READI-CAT® 2 product in the 450 mL presentation

See Product List Enclosed

The discontinuation process is limited to the Apple Smoothie presentation. The other Smoothie READI-CAT® 2 presentations in the 450 mL bottle will continue to be available on the market.

Banana Smoothie READI-CAT® 2 Barium Sulfate Suspension (2.1% w/v, 2.0% w/w), 250 mL

450302 7250 24 �Banana Smoothie READI-CAT® 2 Barium Sulfate Suspension (2.1% w/v, 2.0% w/w), 450 mL

450304 7450 24The discontinuation process is limited to the 250 mL presentation. Banana Smoothie READI-CAT® 2 and Creamy Vanilla Smoothie READI-CAT® 2 in the 450 mL bottle will continue to be available on the market.

Creamy Vanilla Smoothie READI-CAT® 2 Barium Sulfate Suspension (2.1% w/v, 2.0% w/w), 250 mL

450306 7650 24 �Creamy Vanilla Smoothie READI-CAT® 2 Barium Sulfate Suspension (2.1% w/v, 2.0% w/w), 450 mL

450305 7550 24

READI-CAT® 2 Barium Sulfate Suspension (2.1% w/v, 2.0% w/w), 900 mL Bottles

450110 729 12 �READI-CAT® 2 Barium Sulfate Suspension (2.1% w/v, 2.0% w/w), 450 mL

See Product List Enclosed The discontinuation process is limited to the 900 mL bottle and the 1900 mL jug presentations. The 450 mL bottle presentation will continue to be available on the market.

READI-CAT® 2 Barium Sulfate Suspension (2.1% w/v, 2.0% w/w), 1900 mL Jugs

450106 726 4 �READI-CAT® 2 Barium Sulfate Suspension (2.1% w/v, 2.0% w/w), 450 mL


READI-CAT® Barium Sulfate Suspension (1.3% w/v, 1.2% w/w), 450 mL

450109 728 24 �READI-CAT® 2 Barium Sulfate Suspension (2.1% w/v, 2.0% w/w) 450 mL or any Smoothie READI-CAT® 2 product

See Product List Enclosed READI-CAT® 2 and READI-CAT® 2 Smoothies are ready-to-use suspensions with a 2% w/v concentration, specifically designed for enhancement of the GI tract during CT imaging. Doses and modalities of use are not different from READI-CAT® and E-Z Cat®. They are supplied in individual 450 mL doses which are very convenient for the patient to consume.

READI-CAT® Barium Sulfate Suspension (1.3% w/v, 1.2% w/w), 900 mL Bottles



READI-CAT® Barium Sulfate Suspension (1.3% w/v, 1.2% w/w), 1900 mL Jugs



E-Z-Cat® Barium Sulfate Suspension (4.9% w/v, 4.6% w/w), 225 mL



Esopho-Cat® Barium Sulfate Esophageal Cream (3.0% w/w), 30 g

450111 738 24 �With the current CT technology, the clinical need for such a contrast agent in CT is almost non-existent. A neutral contrast agent (like VoLumen®) can be used as an alternative to Esopho-Cat® in those few patients who would benefit from distension of the esophageal lumen at CT.

IMPORTANT SAFETY INFORMATION:Contraindications: These products should not be used in patients with known gastric or intestinal perforation or hypersensitivity to barium sulfate products.Warnings: Rarely, severe allergic reactions of anaphylactoid nature, have been reported following administration of barium sulfate contrast agents.

Bracco Diagnostics Inc.259 Prospect Plains Road, Building HMonroe Township, NJ 08831 USAPhone: 609-514-2200Toll Free: 1-877-272-2269 (U.S. only)Fax: 609-514-2446

©2013 Bracco Diagnostics Inc. All Rights Reserved.13-071813

Please contact your local sales representative to discuss any questions you have about Bracco Diagnostics Inc. barium products, protocols or ordering information.

For prescribing information, call Bracco Professional Services at 1-800-257-5181, Option 2

For more information about Bracco Products, visit http://imaging.bracco.com/us-en or call Bracco Customer Service at 1-877-272-2269, Option 2

®/™ indicates trademark of E-Z-EM, Inc. or E-Z-EM Company, Inc.

barium product portfolio update - rsna 2013rsna2013.rsna.org/files/639/barium product portfolio...

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