Personal Information

Name

Adress

Telefon

E-Mail

Date of Birth /Place

Work permit

Education

OCT 2012-APR 2015

Academic Projects

Master Thesis

OCT 2014-APR 2015

Projects

JUN 2014-SEP 2014

SEP 2013-MAY 2014

MAY 2013-SEP 2013

Master of Science, International Graduate Studies (IGS) in Chemistry.

University of Siegen, Germany, GPA – 2,0

Scholarship -3,600euros“Deutschland stipendium, Studienforderfonds Siegen e.V”

University of Siegen, Germany.

“Investigation and synthesis of metal mediated coupling reactions of cationic hetarenes - Benzo [b]

quinolizinium derivatives”.

Developed new synthetic strategy for the targeted product and established retrosynthetic

analysis schemes.

Extensive literature research using SciFinder, e Molecules and portrayed schemes in

ChemBioDraw, ISIS, ChemDoodle.

Investigated on Pd-mediated cross-coupling reactions in C-H, C-X (Br, I, OTs, Tf) and C-B

activation.

Practiced TLC, column chromatography (Flash, IEX, and SEC), HPLC, and GC-MS

principles for purification process.

Isolated new innovative unknown coupling derivatives in moderate to good yields with

high purity.

Characterized the unknown organic compounds with advanced spectroscopy (UV-Vis, IR,

1D and 2D NMR, ESI-MS).

Reported the obtained results and writing manuscript discussions for research publications.

1. “Synthesis of the macro molecular C-C coupled organic compounds by Sonogashira

coupling- Metal phenanthroline complex Nano switches”-University of Siegen. Investigated on Heteroleptic and Homoleptic self-molecular assemblies and molecular

Nano switches.

Performed Multi-Step complex organic reactions and isolated the desired products in good

yields.

Synthesized Cu and Zn ligated molecular Nano switch as a catalytic ON/OFF station.

2. “Synthesis of [2, 2, 2] heptamethine bridged cyanine dyes-A selective

G-Quadruplex DNA stabilizing ligand Probes”-University of Siegen.

Synthesized and isolated new unknown 2 biologically active cyanine class of dyes, through

multi-step organic synthesis.

Characterized the isolated compounds by COSY, HSQC, HMBC, NOESY and ESI-MS.

Investigated on binding interactions of cyanine dyes with duplex Calf Thymus DNA (Ct

DNA) and telomere sequence (G-Quadruplex) DNA.

Applied bio-analytical methods; such as CD, LD, Fluorimetry, photometry, FRET thermal

stability analysis, NMR, dialysis, Iso-thermal calorimeter for binding studies.

Developed new G-quadruplex stabilizing Intercalators.

3. “Quantitative determination of diclofenac concentrations in environmental water samples

and obtaining LOD and LOQ limits-Liquid chromatography-Electrospray Ionization-

Triple quadruple mass spectroscopy in SIM mode (LC-ESI-QQQ/MS”- University of

Siegen.

Environmental samples concentrated through “Solid extraction” principle and analytical

samples of desired concentrations were developed through serial dilutions.

Developed method of analysis for the hybrid analytical system HPLC-ESI-QQQ/MS in

selective ion mode.

Bandaru Siva Sankar Murthy

Siegener Str.24, 57223, Kreuztal, Deutschland

+49 17641776947

ashshiva.s@gmail.com,venkata.bandaru@student.uni-siegen.de

05.08.1985 / Bihar, Indien

Europe

Curriculum Vitae

JAN 2009- JAN 2010

APR 2005-AUG 2007

Master Thesis

FEB 2007-AUG 2007

MAR 2002-APR 2005

Professional Experience

JAN 2015-Present

JAN 2011- SEP 2012

FEB 2010-DEC 2010

PG Diploma In Clinical Research

Institute of Clinical Research India, Hyderabad.

Sponsored by Abbott India Ltd.

Professionally trained in

Basics of Clinical research, ethical principles of biomedical research involving human

subjects (CIOM guidelines).

ICH-GCP E6 Guidelines, Ethics in Clinical research, Regulations (Schedule Y, New Drug

Applications) and quality and SAE (Serious Adverse Event Reporting) in clinical research.

Prepared CRF (Case Record Forms), IC (Informed Consent forms), PI (Patient Information

sheets), Protocol designing.

Conducted PMS (Post Marketing Surveillance Studies)

Clinical data management, Trail management, drug safety and pharmacovigilance.

Master of Science, Specialization Organic Chemistry.

Andhra University, India, GPA- 1,7

“Synthesis novel 4-substituted arylidene-2-[5-(2, 6-dichloropheny) -3-methyl-1, 2-oxazol-4-yl] -1, 3-

oxazol-5-ones”.

Synthesized biologically active dye complex through multi-step organic synthesis and

isolated the pure compound through flash column, size exclusion, ion-exchange

chromatography methods and identified through advanced spectroscopy principles Bachelors Of Science, (Mathematics, Physics and Chemistry).

Andhra University, India. GPA- 1.5

University of Siegen, Germany

Scientific Research associate

Designing new fused heterocyclic DNA binding (intercalating or Groove binding) organic

compounds.

Retrosynthesis, planning organic reaction schemes and researching through scientific

literature using SciFinder, ChemSpider, REAXYS.

Performing Multi-step organic synthesis, isolating, purifying through chromatography or

recrystallization and characterizing the unknown derivatives through advanced

spectroscopic methods (UV-Vis, IR, NMR and ESI-MS).

Reporting results on regular basis in monthly team meets through Power point

presentations.

Generating manuscripts for new results and preparing the descriptions for the scientific

publications.

Merck Sharp & Dhome Pharmaceuticals India Ltd.

Designation: Business Manager (Endocrinology)

Scientific support to the marketing team and organizing training sessions for a group of 5

people on pharmacology and chemistry of DPP-4 inhibitor (Sitagliptin) and GLP-1

receptor agonists.

Conducted Continuous medical education sessions for the medical fraternity.

Prepared quarterly budget plan for the scientific marketing activities. Improved sales of JANUVIA

TM with 100% target achievements.

AstraZeneca pharmaceuticals India.

Designation: Scientific Officer (Endocrinology)

Organized scientific pharmacology studies (PMS) data of Saxagliptin- ONGLYZATM

(DPP-4 inhibitor) for the launch in to the Indian pharmaceutical market.

Intensive clinical data management for safety reports.

Regular contacts with clinical research coordinators and documenting the PI data, SAE

information.

Professionally trained in “Novel approach in Diabetes management-DPP-4 inhibitors

and incretin- based therapies”

JAN 2008- JAN 2010

Competitive skills

Languages

Hobbies

References

Abbott India Ltd.

Designation: QC & QA executive for 1 year and promoted to Hyderabad regional office as business

training executive.

Performed IPQC, Finished product HPLC, GC, and dissolution analysis and developed

Certification of Analysis (COA), maintained Method of Analysis (MOA) records.

Controlling the BMR records and other qualitative analysis reports for Audits.

Professionally trained in Pharmacology, Anatomy & Physiology and Marketing

communication soft skills. Monitoring product sales and managing stakeholders for product market availability.

English (Fluent)/ Deutsch (Good)/ Hindi (Fluent)/ Telugu (Native Speaker)

State level professional cricket player.

Playing Indian flute (Bansuri) classical.

Prof. Dr. H.K. Ihmels, University of Siegen – Organic chemistry professor and Supervisor. Dr. Yerramsetty Nanaji, University of Siegen- Lab supervisor. Prof. Dr. Engelhard, University of Siegen- Analytical chemistry professor.

Contact details of the referees can be provided upon request.

I hereby confirm the information provided by me is true to the best of my knowledge

Bandaru Siva Sankar Murthy