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    Bacterial skin Infection

    University of Hargeisa Medical Faculty(UoH-MF)

    Dermatology Department

    Dr. Ismail Adam Abdilahi

    2008

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    Predisposing factors

    Trauma or abrasion of the skin

    Viral disease .

    Primary dermatoses e.g. Eczema .

    Poor hygiene and overcrowding

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    Staph. infectionsImpetigo contagiosum .

    Boils .

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    Impetigo contagiosumDefinition :Acute contagious superficial

    pyogenic infection of the skin.Types :

    Non-bullousbullous

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    Non-bullous impetigo

    Caused by staph. inassociation with strep.or by strep alone.

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    Clinical features:

    Age : mainly preschoolSites : face,limbs andscalp are common.

    Palms and soles are notaffected.

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    There is thin-walled vesicleson erythematous base that

    soon rupture yellowishbrown crusts that dry and

    separate erythema whichfades without scarring.

    Complication : post-strep.acute glomerulonephritis .

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    Bullous impetigoCaused by staph throughstaph toxin (exfoliatin)

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    Clinical features:

    Age : all agesSite : face is oftenaffected but mayoccur any whereincluding palms and

    soles

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    The bullae are less rapidlyruptured( persistent for 2-3days) and become much

    larger. When rupture thinbrownish crust.

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    Treatment of impetigoUse antiseptic e.g. potassiumpermanganates.

    Topical antibiotic .Systemic antibiotics .

    Treatment of predisposingfactors: e.g. Scabies.

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    BoilsPainful erythematous tenderpapular lesions which are

    related to infection of hairfollicles .

    Sites: neck, axillae, buttocks,and thighs.

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    If infection spreads to

    involve several folliclescarbuncle.

    Screen for diabetesmellitus in case of

    recurrent boils.

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    Treatment of boils:

    Is similar to that ofimpetigo but systemic

    antibiotics are oftennecessary.

    Surgical incision may beneeded.

    t t

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    treptococca

    infections

    Erysipelas.

    Ecthyma.

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    ErysipelasWidespread erythema andcellulitis due to infection of thedermis and upper cutaneoustissue by group A strep reaching

    the dermis through a wound or asmall abrasion red, swollen andtender skin

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    Lymphangitis andlymphadenitis are frequent.

    Common sites are legs andface.

    Complications:lymphedema, subcutaneous

    abscess, septicemia, nephritisand meningitis.

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    Treatment :Penicillin 1 g/day orErythromycin .

    Treatment of anyunderlying skin disease e.g.chronic fissuring.

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    EcthymaChronic ulceration due to

    infection of the dermis by staph

    and strep.Often prolonged so needs

    intensive local antiseptic

    treatment combined withsystemic antibiotics.

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    infections

    -Cutaneous tuberculosis.

    -Leprosy .

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    tuberculosis

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    Lupus vulgarisMost common form ofskin tuberculosis.

    I f i

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    Infection throughhematogenous spread orprimary inoculation of the skinwith mycobacterium

    tuberculosis.Histopathology : granulomas

    with central caseation and theorganism can bedemonstrated.

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    Clinical features:Erythema, scaling andscarring plaques.

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    T t t

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    Treatment :multi-drugtherapy for 6-9 months :

    Rifampicin 600mg daily (450mgfor body wt less than 55kg)

    INH 300mg dailyBoth half an hour before breakfastfor 6 month

    Pyrazinamide 1.5-2gm daily for 2months only

    TREATMENT OF

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    TREATMENT OF

    LEPROSY

    PAUCIBACILLARY : for6 month .

    Rifampicin 600 mg monthlyDapsone 100 mg daily .

    MULTIBACILLARY

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    MULTIBACILLARY :

    for 2 years .Rifampicin 600 mg +

    clofazimin 300 mgmonthly .

    Dapsone 100 mg +clofazimin 50 mg daily .

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