Mistaken IdentityMany have mistakenly brought their loved ones to get exorcised believing that the sudden erratic and sometimes violent behavior was due to demonic possession

Autoimmune Encephalitis

A Disease of Madness

History Behind the DiseaseAutoimmune encephalitis hasn’t always been recognized for what it is, but now it’s becoming better

understood as a cause of cognitive degeneration and psychological disarray. Half the cases have gone undetected, even though it is well understood as a distinct entity.

This is because detection of the disease can be through symptoms that are related to many, much more prevalent illnesses. Though treatment can be effective, it is a ticking time bomb for

treatment of the wrong diagnosis, potentially triggering escalation of symptoms.

Symptoms and DiagnosisDetection of antibodies in deep grey matter neurons such as the N-methyl-D-asparate (NMDA) receptors or

voltage-gated potassium channels (VGKC) has been observed.

These auto-antibodies (NMDA,VGKC) can be found through serum lab tests, and magnetic resonance imaging can show inflammation, and spinal tap can reveal auto-antibodies and other biomarkers in the cerebrospinal fluid that point to autoimmune encephalitis.

The Terror-toma “Teratoma”

An undeveloped Oocyte that grows out of stem cells

and hormones

Afflicts 50% of Women with NMDA-type encephalitis

Treatment and PrognosesImmunomodulating therapies like intravenous

immunoglobulin (IVIG), glucocorticosteroids, plasma exchange and drugs like cyclophosphamide, rituximab, mycophenolate mofetil, azathioprine, in combination or individually, have all produced good results and are readily available.

Current research in Anti-NMDA encephalitis reveals that 25% of patients suffer from severe deficits or death.

There is a 12% relapse risk in 2 years. Early treatment is one of the most important predictors of a good outcome.

Resources and SupportAutoimmune Encephalitis Alliance- www.aealliance.orgAE Clinicians Network: http://wp.me/p41oPS-luThe Encephalitis Society- www.encephalitis.infoBooks: Brain on Fire: My Month of Madness Susannah Cahalanhttp://www.ctvnews.ca/parents-warn-of-mystery-illness-misdiagnosed-in-kids-1.701777