australian and new zealand intensive care research centre ... · a/prof ian seppelt dr guillaume...

Australian and New ZealandIntensive Care Research CentreAnnua l Repor t 2019

32

Director 3

About the ANZIC-RC 4

Governance 5

Staff 6

Students 7

Adjuncts 8

Visitors 9

Affiliates 9

Senior Research Fellows 10

Research Grants Active 11

NHMRC Funding Graphs 14

Awards 15

Publications 16

Publications Graph 22

Presentations 23

Table of Contents Director

It is with great pleasure that I introduce the 2019 annual report of the ANZIC Research Centre.

In 2019, the Centre had 190 publications and major funding for exciting new collaborations. During this year, the Centre was leading ten NHMRC-funded randomised controlled trials in intensive care medicine.

Trial results for ICU-ROX (Conservative Oxygen Therapy during Mechanical Ventilation in the ICU, NEJM), PHARLAP (Maximal Recruitment Open Lung Ventilation in Acute Respiratory Distress Syndrome, Am J Resp Crit Care Med), and SPICE III (Early Sedation with Dexmedetomidine in Critically Ill Patients, NEJM) were presented and published.

New funding included $4.9 million from the NHMRC for a sedation study in older critically ill patients (Shehabi, Bellomo, Howe, Hodgson, Presneill, Bailey, Reade, Webb, Seppelt et al); and NHMRC Investigator Grants for Carol Hodgson (Early interventions to improve the quality of survival after critical illness) and Emma Ridley (Generation of high quality, clinically relevant knowledge to inform global nutrition practice during critical illness).

I would like to thank our whole team of wonderful staff, adjuncts, students, affiliates and visiting researchers for their dedication to our Centre and its incredibly prolific research projects and programs.

Professor D. Jamie Cooper AODirector ANZIC-RC

54

The Australian and New Zealand Intensive Care Research Centre (ANZIC-RC) is the bi-national centre for the development, coordination and execution of pivotal multicentre randomised controlled trials (RCTs) in critically ill patients. The outcomes of its research have changed medical care in Australia and internationally, improved patient outcomes and lowered health care costs. The parallel role of the ANZIC-RC is a national teaching centre for doctoral, postdoctoral and international clinician researchers in critical care medicine.

It was established in 2006, with funding from the National Health and Medical Research Council and Monash University. The ANZIC-RC is part of the University’s School of Public Health and Preventive Medicine. It is located within the Alfred Research Alliance, one of Australia’s largest and best supported applied research environments, in the precinct of one of Australia’s busiest hospitals, The Alfred, Melbourne.

The ANZIC-RC offers a range of services, from research advice to complete project management. Advice and assistance is available from experienced intensive care unit (ICU) researchers, data management/bio-statistical

consultants, project managers, epidemiologists and health economists. The Centre coordinates and conducts comprehensive research programs including observational studies; feasibility projects; and large multi-centred, interventional, randomised controlled trials. It has the ability to support small, medium and large clinical trials.

The principal aims of the ANZIC-RC are to:• Conduct high-impact, large-scale, investigator

-initiated clinical trials designed to determine best and most cost-effective practice in Intensive Care Medicine (ICM)

• Increase the quality of clinical trial design and biostatistical analysis in this field

• Be readily accessible to all Australian and New Zealand clinician-researchers in critical care

• Expand the national and international reach of large Australian and New Zealand led trials

• Introduce systems to integrate research results into clinical practice by promulgating research-based practice guidelines

• Develop integrated clinical research programs that provide the training ground for future clinical trialists in the field of ICM

• Encourage and support clinician researchers in research theory, study design, study conduct, data analysis and scientific writing.

About the ANZIC-RC ANZIC-RC Governance - Advisory Board

Prof Jamie Cooper Director

ANZIC-RC

Prof Rinaldo Bellomo

Co-DirectorANZIC-RC

Prof Sophia Zoungas

HeadSPHPM Monash

A/Prof Colin McArthur

Representative New Zealand

Prof Carol Hodgson

Co-Deputy Director

ANZIC-RC

Prof David Pilcher

Representative ANZICS-CORE

A/Prof CraigFrench

Immediate-Past Chair

ANZICS-CTG

Dr Shay McGuinness

Representative New Zealand

Prof AndrewUdy

Co-Deputy Director

ANZIC-RC

Prof Alistair Nichol

Co-Deputy Director

ANZIC-RC

Prof SandraPeakeChair

ANZICS-CTG

76

ANZIC-RC Staff

A/Prof ZoeMcQuilten

Haematologist

Ms Lisa Higgins

Research Fellow

Dr Emma Ridley

Senior Research Fellow

Dr TomokoFujii


Ms EmmaDonoghueResearch

Fellow

Ms Belinda Howe

Senior Project Manager CLIP

Ms MeredithYoung

Project ManagerPHARLAP

Mr Tony Trapani

Research Manager

Ms Victoria King

Project Manager Nutrition

Ms Amanda Martin

Administration Manager

Prof Alistair Nichol

Co-Deputy Director

Prof Michael Bailey

Statistician

Ms Lynne Murray

Business Manager

Prof JamieCooper Director

Prof Rinaldo Bellomo

Co-Director

Prof Carol Hodgson

Co-Deputy Director

Prof Steve Webb

Intensivist

A/Prof DarylJones

Intensivist

ANZIC-RC Students

Dr HelenAckland

PhD Conferred 2012

Dr AntoineSchneider

PhDConferred 2015

A/Prof Daryl JonesPhD

Conferred 2015

Dr Ralph Tramm

PhD Conferred 2016

Dr MattBrainPhD

Scholar

Dr DashiellGantner

PhD Scholar

Dr Neil Glassford

PhD Conferred 2017

Dr Elizabeth Moore

PhD Conferred 2014

Ms BiancaLevkovich

PhD Scholar

A/Prof NeilOrford

PhD Conferred 2018

Dr EmmaRidleyPhD

Conferred 2018

Ms GemmaPound

PhD Scholar

Dr Nor’azim Mohd Yunos

PhD Conferred 2017

Mr Simon Landes

BMedSc (Hons)Completed 2012

Mr EdwardQuine


Ms Lisa Higgins

PhD Scholar

Dr Eldho PaulPhD

Conferred 2018

Ms MadelineCenedese

BHlthSc (Hons)Completed 2015

Mr ZacharyO’Brien


Dr RafidahAtanPhD

Conferred 2018

Dr RaviTiruvoipati

PhD Conferred 2019

Dr AidanBurrell

PhD Conferred 2019

Dr Tim Coulson

PhD Conferred 2018

Ms MichellePatonPhD

Scholar

Ms NatalieLinke

Project ManagerEXCEL

Dr GlennEastwood


Prof Andrew Udy

Co-Deputy Director

Dr Joanne Brooker

Research Fellow

Dr FumitakaYanase

PhD Scholar

Mr Chun Sang Kwan

BBiomedSc(Hons)Completed 2016

Mr CameronGreen

Project ManagerREMAP-CAP Global

Ms Bridget Ady

Project Manager TAME

Ms JananiSivasuthan

Project ManagerTEAM

Ms Jane Parker

Project ManagerREMAP-CAP

Ms VanessaSingh

Project ManagerTAME

Dr HusnaBegum

Project ManagerSPRINT-SARI

Ms Kate Lambell

Research Fellow

Mr Michael Mackie Project Officer

Dr Eliza Miller

Project Manager INTENT

Dr Camila Battistuzzo

Project ManagerPATCH

Ms Kelly Ottosen

Project ManagerBLENDER

Dr Eldho Paul

Research Fellow

Dr Oana Tatucu

Research Fellow

Mr LonniGomes

Research and Admin Officer

Mr Daniel Engeler Project Officer

Dr AndrewFlintPhD

Scholar

Mr DanielEngeler


Ms ClaireTipping

PhD Scholar

Ms Jenna LangPhD

Scholar

Ms VickiPapanikolaou

Project ManagerEPO-TRAUMA

Ms TessaBroadley

Project Officer

Mr BentleyFulcher


Dr VinodhNanjayya

PhD Scholar

Ms Shirley Vallance

Project ManagerBONANZA

98

Dr Neil Glassford

Dr DashiellGantner

Prof JacquesDuranteau

A/Prof AnthonyDelaney

Dr AndrewFlint

A/Prof CraigFrench

Dr ArneDiehl

Dr Mark Finnis

ANZIC-RC Adjuncts

Prof CécileAubron

Prof TraceyBucknall

Prof GillesCapellier

Prof MarianneChapman

A/Prof AndrewDavies

Dr PeterKruger

A/Prof ColinMcArthur

Dr ShayMcGuinness

A/Prof Cristina Morganti-Kossmann

Prof JohnMyburgh

Ms LynetteNewby

A/Prof RachaelParke

Prof SandraPeake

Prof VillePettilä

Prof David Pilcher

A/Prof JeffreyPresneill

Prof YaseenArabi

Dr Samir Haddad

Ms SueHuckson

Prof OlivierHuet

Prof MichaelReade

A/Prof MatthieuSchmidt

A/Prof IanSeppelt

Dr Guillaume Carteaux(France)2010-1

Prof GillesCapellier(France)2011-2

A/Prof Matthieu Schmidt (France)2013-4

Dr AudeGarnero(France)2013-4

Prof KathyRowan

(UK)2013 and 2015

Prof Theodore (Jack) Iwashyna

(USA)2015

Prof Rob Sladen(USA)2017

ANZIC-RC Affiliates

Dr TàiPham

Prof KathyRowan

Mr Alex Poole

Dr RalphTramm

ANZIC-RC Visitors

A/Prof VincentPellegrino

Dr Luca Cioccari

Dr TomokoFujii

(Japan)2018

Dr Kapil DevSoni

Dr PaulSecombe

A/Prof NeilOrford

Dr AdamDeane

Dr NoraLuethi

Mr ZacharyO’Brien

Mr Mick Stephenson

A/Prof Ravi Tiruvoipati

Ms TriciaWilliams

Ms JudyWills

Prof MarkusSkrifvars

Prof Rob Sladen

Ms LorraineLittle

Dr AidanBurrell

Dr TimCoulson

Dr Shuji Okahara(Japan)

2019

Ms Eveline Wiegers

(Netherlands)2019

Dr KatsunoriMochizuki

(Japan)2019

Dr VirginiaNewcombe

Ms Lizzie Hudson

Ms Liadain Reid

Dr JoshIhle

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ANZIC-RC Senior Research Fellows

A/Prof DarylJones

(Australia)2006

Prof AlistairNichol

(Ireland)2007

Dr AndrewWestbrook

(Ireland)2008

Prof Cécile Aubron(France)

2010

Prof CarolHodgson

(Australia)2011

Prof VillePettilä

(Finland)2009

A/Prof Maija Kaukonen(Finland)2012-3

Dr DashiellGantner

(Australia)2012

A/Prof AndrewDavies

(Australia)2014-5

Research Grants ActiveTitle Agency /

Grant TypeChief Investigator/s Year/s of

FundingTotal

AmountAdministering Institution

Addressing Australia’s National Transfusion Research Priorities

NHMRC #1189490Synergy Grant

Wood E, McQuilten Z, Cameron P, Cooper DJ, Reade M, Higgins L, et al

2020-2024 $5,000,000 Monash

SPICE IV: Sedation Practice in Intensive Care Evaluation: Early Sedation with dexmedetomidine in Older Ventilated Critically Ill Patients RCT

NHMRC #1186863Project Grant

Shehabi Y, Bellomo R, Howe B, Hodgson C, Presneill J, Bailey M, Reade M, Webb S, Campbell L, Seppelt I

2020-2024 $4,995,197 Monash (ANZIC-RC)

The impact of sepsis in critically ill patients

NHMRC #1173079Investigator Grant

Myburgh J 2020-2024 $2,101,595 University of NSW

Early interventions to improve the quality of survival after critical illness


Hodgson C 2020-2024 $1,243,891 Monash (ANZIC-RC)

Generation of high quality, clinically relevant knowledge to inform global nutrition practice during critical illness


Ridley E 2020-2024 $561,800 Monash (ANZIC-RC)

COMPASS: Clinical Outcomes Measurement in Perioperative Medicine, Anaesthesia and Surgery

ANZCA 20/032Project Grant

Reilly J, Brown W, Gabbe B, Hodgson C, Paul E

2020-2021 $160,000 Monash

Length of storage of red blood cell units as a risk factor for hospital-acquired infections: IPDMA (CA$110,000)

CIHR #419298Project Grant

Fontanela PS, Fergusson D, Cooper D, ... McQuilten Z, et al

2020-2021 $120,789 McGill University,Canada

Improving the quality of survival for patients with acute life-threatening heart failure

NHFFellowship

Hodgson C 2020-2024 $200,000 Monash (ANZIC-RC)

Clinical Impact of Red Cell Storage Age: IPDMA of Four Recent Large Randomized Trials (US$133,418)

NIH #1R21HL145377-01Project Grant

Assmann SF, Steiner M, ... Cooper DJ, McQuilten Z, Nichol A, French C, et al

2020 $191,293 University of Minnesota, USA

Australian Partnership for Preparedness Research on Infectious disease Emergencies

APPRISETravel Grant

Begum H 2020 $3,000 Monash (ANZIC-RC)

National Heart Foundation Collaboration and Exchange Award

NHFTravel Award

Hodgson C 2020 $5,000 Monash (ANZIC-RC)

BONANZA: Brain Oxygen Neuromonitoring In Australia And New Zealand Assessment Trial

NHMRC/MRFF#1167706Project Grant

Udy A, Cooper DJ, Nichol A, Rosenfeld J, Menon D, Bailey M, Drummond K, Higgins A

2019-2023 $1,055,886 Monash (ANZIC-RC)

BONANZA: Brain Oxygen Neuromonitoring In Australia And New Zealand Assessment Trial


Udy A, Cooper DJ, Nichol A, Rosenfeld J, Menon D, Bailey M, Drummond K, Higgins A

2019-2023 $2,703,830 Monash (ANZIC-RC)

CLIP: Trial of cryopreserved platelets vs. conventional liquid-stored platelets for management of post-surgical bleeding

NHMRC #1156641 Project Grant

Reade M, Marks DC, French C, McQuilten Z, Weinberg L, Irving D, et al

2019-2022 $1,825,648 Monash (ANZIC-RC)

EPO-TRAUMA: Trial of Erythropoietin alfa vs. placebo in critically ill trauma patients

NHMRC/MRFF#1170001Project Grant

French C, Nichol A, Bellomo R, Cooper DJ, Bailey M, Higgins A, McArthur C, Hodgson C

2019-2023 $3,499,109 Monash (ANZIC-RC)

PATCH II: Pre-hospital anti-fibrinolytics for traumatic coagulopathy and haemorrhage


Bernard S, Mitra B, Gruen R, Gantner D, Reade M, Burns B, Balogh Z

2019-2021 $656,155 Monash (ANZIC-RC)

Alfred Physiotherapy Research Fellowship

Alfred HealthFellowship

Pound G 2019 $4,000 Alfred


ANZCA Project Grant


2019-2020 $10,000 Monash

ACE E-CPR: Actual Cost Estimation of Extracorporeal Cardio-Pulmonary Resuscitation study

ARCProject Grant

Nanjayya V 2019-2020 $10,000 Alfred


ASAProject Grant


2019-2020 $25,000 Monash

Prof MarkusSkrifvars(Finland)2016-7

Dr NoraLuethi

(Switzerland)2017-8

Dr Tomoko Fujii

(Japan)2018-9

1312

Research Grants Active (continued) Research Grants Active (continued)

Title Agency / Grant Type

Chief Investigator/s Year/s of Funding

Total Amount

Administering Institution

STARRT-AKI: STandard versus Accelerated initiation of Renal Replacement Therapy in AKI

Canadian Institutes of Health ResearchProject Grant

Bagshaw SM, Wald R, Adhikari N, Gallagher M, ... Bellomo R, Higgins A, Liu K, Nichol A, et al

2018-2021 $1,556,776 University of Alberta

Bridging Postdoctoral Fellowship Monash FMNHSFellowship

Ridley E 2018-2019 $30,000 Monash (ANZIC-RC)

Improving outcomes in patients with community-acquired severe sepsis: The role of pre-hospital antibiotics

NHMRC #1124532Fellowship

Udy A 2017-2020 $265,138 Monash (ANZIC-RC)

STARRT-AKI: STandard versus Accelerated initiation of Renal Replacement Therapy in AKI


Gallagher M, Bagshaw S, Endre Z, Gattas D, Udy A

2017-2021 $2,112,447 The George Institute

TAME: Targeted Therapeutic Mild Hypercapnia After Resuscitated Cardiac Arrest


Bernard S, Eastwood G, Bellomo R, Stub D, Archer J, Hodgson C

2017-2021 $2,069,878 Monash (ANZIC-RC)

TEAM: Treatment of invasively ventilated adults with Early Activity and Mobilisation Study


Hodgson C, Gabbe B, Webb S, Presneill J, Young P, Iwashyna T

2017-2021 $1,467,137 Monash (ANZIC-RC)

INTENT: Intensive nutrition in critically ill adults: A pilot randomised controlled study (US$1,852,684)

Baxter Healthcare CorporationProject Grant

Ridley E, Chapple L-A, Davies A, Deane A, McGuinness S, Hodgson C, Parke R, Cooper DJ, Bailey M

2017-2021 $2,470,246 Monash (ANZIC-RC)

TAME-RENAL: Targeted therapeutic mild hypercapnia after resuscitation cardiac arrest: renal outcomes

Baxter Healthcare CorporationProject Grant

Eastwood G, Nichol A 2017-2021 $47,540 Monash (ANZIC-RC)

TAME: Targeted Therapeutic Mild Hypercapnia After Resuscitated Cardiac Arrest

HRB, Ireland DIFA-2017-036Project Grant

Nichol AD, et al 2017-2020 $1,377,281 University College, Dublin

ICU-ROX: Comparing conservative oxygen therapy to standard care in mechanically ventilated adults in the Intensive Care Unit (NZ$1,404,525)

Health Research Council of NZProject Grant

Young P, Bellomo R, et al 2017-2020 $1,404,525 MRINZ

Future Leaders Fellowship: Recovery after critical illness from cardiovascular failure

Heart Foundation Research Fellowship

Hodgson C 2017-2020 $520,000 Monash (ANZIC-RC)

PLUS: PLasmalyte versUs Saline for intravenous fluid therapy in ICU(NZ$1,385,525)


Young P, Bellomo R, et al 2017-2020 $1,289,756 MRINZ

Pre-hospital anti-fibrinolytics for traumatic coagulopathy and haemorrhage (NZ$943,384)


McArthur C, et al 2017-2019 $878,176 MRINZ

TRiCS III: Transfusion requirements in patients for cardiac surgery (NZ$1,199,468)


McGuinness S, et al 2017-2019 $1,116,666 MRINZ

APPRISE: Australian Partnership (for) Preparedness Research on InfectiouS (disease) Emergencies

NHMRC #1116530Centre for Research Excellence

Lewin S, Sorrell T, McVernon J, Webb S, Kaldor J, Andrews R, Cheng A, Gilbert L, et al

2016-2020 $4,996,416 University of Melbourne

Optimising transfusion support in critical illness and haemotological malignancies


McQuilten Z 2016-2019 $262,251 Monash (ANZIC-RC)

ITACS: IV iron for Treatment of Anaemia before Cardiac Surgery


Myles P, Richards T, Smith J, Cooper DJ, Wood E, et al

2016-2020 $2,285,290 Monash

OPTIMISE-CAP: Optimisation by Platform Trial Involving Multiple Interventions with Simultaneous Evaluation in Community Acquired Pneumonia


Webb S, McArthur C, Berry D, Paterson D, Cheng A, Heritier S, Presneill J, Litton E

2016-2020 $4,413,145 Monash (ANZIC-RC)

Title Agency / Grant Type

Chief Investigator/s Year/s of Funding

Total Amount Administering Institution

EPO-TRAUMA: Phase III trial of EPOetin alfa vs. placebo in critically ill TRAUMA patients (€999,994)

HRB, IrelandDIFA-FA-2018-028Project Grant

Nichol A, Doran P, Curley G, Murray P, Bellomo R, French C

2019-2023 $1,575,329 University College, Dublin

BLING III - Phase III RCT of continuous ß-lactam infusion in the critically ill (NZ$1,195,807)


McGuinness S, Parke R, Freebairn R, Henderson S, McArthur C, Roberts S, et al

2019-2023 $1,144,097 MRINZ

TAME Cardiac Arrest: Targeted Therapeutic Mild Hypercapnia After Resuscitated Cardiac Arrest RCT (NZ$1,199,994)


Parke R, McGuinness S, Bellomo R, Eastwood G, Buehner U, Gilder E, ... McArthur C, et al

2019-2022 $1,148,103 MRINZ

TEAM: Targeted Early Activity and Mobilistation in the ICU (NZ$1,011,247)


Young P, ... McGuinness S, ... McArthur C, ... Higgins A, ... Hodgson C, Bailey M, et al

2019-2022 $967,648 MRINZ

National Death Index Linkage for long-term survival

Intensive Care Foundation (ICF)Project Grant

Pilcher D, Litton E, Huckson S, Secombe P, Millar J

2019 $50,000 Alfred

VITAMINS: Vitamin C, Hydrocortisone and Thiamine in patients with septic shock

Intensive Care Foundation (ICF)Project Grant

Luethi N, Udy A, Bellomo R, Deane A, Young P, French C

2019 $48,301 Monash (ANZIC-RC)

LUCID nested-cohort study glycated haemoglobin testing to rapidly identify chronic hyperglycaemia

MACHProject Grant

Deane A, Bellomo R, French C, et al

2019-2021 $75,000 University of Melbourne

Advancing Women’s Research Success Grant Program

Monash FMNHSResearch Grant

Ridley E 2019 $11,000 Monash (ANZIC-RC)

Linking routinely collected Cardiac Surgical and Intensive Care Registry Data to provide near real time monitoring of cardiac surgical performance - national pilot

Monash Partners/MRFF/DoHProject Grant

Pilcher D, Coulson T, Reid C, Chowdhury E, McGiffin D

2019 $104,699 Monash

Partnership Award University of Sydney and National University of Singapore

Seppelt I, Feng M, Nguyen N, Pilcher D

2019 $20,000 University of Sydney

International Exchange in Acute Heart Failure during Critical Illness

NHF Travel Grant

Hodgson C 2019 $5,000 Monash (ANZIC-RC)

NHMRC Practitioner Fellowship Level II


Bellomo R 2018-2022 $329,822 Austin



Cooper DJ 2018-2022 $412,277 Monash (ANZIC-RC)

EXCEL: A collaborative approach to improve outcomes of Australian patients with acute heart failure and cardiac arrest requiring extracorporeal life support

NHMRC #1152793Partnership Grant

Hodgson C, Cooper DJ, Bailey M, Fraser J, Pilcher D, Bernard S, Gattas D, Pellegrino V, Stub D, Higgins A

2018-2020 $692,657 Monash (ANZIC-RC)

BLENDER: Blend to Limit Oxygen in ECMO: A Randomised Controlled Registry Trial


Pilcher D, Hodgson C, Fraser J, Cooper DJ, Burrell A, Pellegrino V, Udy A, Gattas D, Bailey M, Higgins A

2018-2022 $726,004 Monash (ANZIC-RC)

DIAAMOND: Diagnosis of Aplastic Anaemia Management/Outcomes


Wood E, McQuilten Z, et al 2018-2022 $1,750,776 Monash

Protein absorption and kinetics in critical illness


Chapman M, et al 2018-2020 $1,233,268 University of SA

REDDSW2: Trial of weekly-interval red cell transfusion schedule in myelodysplastic syndromes

ANZSBTProject Grant

Mo A, Wood E, McQuilten Z, Stanworth S, Wallis J, Shortt J, Opat S, Daly J, Hodgson C

2018-2019 $17,000 Monash

1514

Research Grants Active (continued) Title Agency /

Grant TypeChief Investigator/s Year/s of

FundingTotal Amount Administering

InstitutionPLUS: Plasma-Lyte 148® versUs Saline study


Finfer S, Myburgh J, Bellomo R, Young P, Gattas D, et al

2016-2019 $5,984,819 University of Sydney

Platform Trial Optimising Interventions in Severe Community Acquired Pneumonia

Health Research Council of NZProgram Grant

McArthur C, Young P, Morpeth S, ... Higgins A, Webb S, et al

2016-2021 $4,410,752 MRINZ

CRE-ACTIONS: Advanced Cardio-respiratory Therapies Improving Organ Support

NHMRC #1079421Centre for Research Excellence

Fraser J, McGiffin D, Lovell N, Bannon P, Tansley G, Pellegrino V, Roberts J, et al

2015-2019 $2,491,450 Prince Charles Hospital, QLD



Myburgh JA 2015-2019 $551,435 University of Sydney

ADRENAL-GEPS: Gene expression profiling in critically ill patients with septic shock


Evans D, Venkatesh B, Powell J, Myburgh JA, Finfer S, Cohen J

2015-2019 $834,269 University of Queensland

SUDDICU: Cluster RCT of selective decontamination of the digestive tract in critically ill ventilated patients


Seppelt I, Myburgh JA, Finfer S, Iredell J, Davis J, Marshall A, Taylor C, Cuthbertson B

2015-2019 $3,960,000 University of Sydney

TARGET: The Augmented versus Routine approach to Giving Energy Trial


Chapman M, Peake S, Bellomo R, Horowitz M, Davies A, Deane A

2015-2019 $3,534,236 Monash (ANZIC-RC)

TREATT: Trial to evaluate anti-fibrinolytic therapy in thrombocytopenia


Wood E, Stanworth S, Cole-Sinclair M, Westerman D, Szer J, Estcourt L, McQuilten Z

2015-2019 $1,012,635 Monash

Centre for Research in Intensive Care (DKK 36,000,000)

Danish Strategic Research Council

Perner A, ..., Myburgh JA, Pettilӓ V, ... , Rowan K, et al

2015-2020 $7,400,000 Copenhagen University

Improving outcomes in critical illness (€2,350,000)

Health Research Board, IrelandProject Grant

Nichol A, Cooper DJ, Laffey J, McLoughlin P, Ryan T, McAuley D


TRANFUSE IRELAND: STandaRd Issue TrANsfusion versuS Fresher red blood cell Use in intenSive carE (€799,999)

Health Research Board, IrelandProject Grant

Nichol A, Cooper DJ, Laffey J, McLoughlin P, Ryan T, McAuley D


Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) (Total Grant €30m, Australian component €279,499)

European Union’s Seventh Framework Programme for Research (EU FP7)

Maas A, Menon D, Hill S, Steyerberg E, von Steinbüchel N, ... Cooper DJ, et al

2013-2020 $409,491 Monash(ANZIC-RC)

Total $98,410,540

NHMRC Funding Graphs (ANZIC-RC Administered Grants)

Awards

Congratulations to our team members who received awards in 2019 including:

• Member (AM) in the Military Division Of The Order Of Australia awarded to Brigadier Michael Reade for exceptional performance of duty as the Director of Clinical Services of the 2nd General Health Battalion and Professor for Military Medicine and Surgery. Brigadier Reade demonstrated exceptional vision, drive and professional skill in developing Army’s operational trauma capability. His internationally recognised research enhanced the care of military personnel globally and has made a substantial positive contribution to the Australian Defence Force’s reputation. His clinical leadership was pivotal to the 2nd General Health Battalion becoming the first deployable military hospital in the world to be externally accredited at the standard of a civilian trauma centre.

• US Military Health System Research Symposium (2018) best collaboration between an academic and military research team awarded to Michael Reade and his research team for the CLIP pilot trial, the first time an Australian team has won a prize at the conference.

• Doctor of Science from UNSW Sydney awarded to John Myburgh for his outstanding contribution to the field of critical care and trauma

• Victorian Premier’s Award Finalist: Emma Ridley• BioMedVic Clinician Researcher Career Recognition Award to identify and honour individuals with an

outstanding record in patient-based research and clinical work and who are regarded as having had substantial influence among peers and colleagues, this Award recognises exemplary supervision and mentoring of other clinical researchers: Rinaldo Bellomo

• Highly Cited (HiCi) Researcher: Rinaldo Bellomo was officially named a Highly Cited Researcher for the 6th time in a row (one of only 4 in Critical Care Medicine in the world). Rinaldo is among an elite few recognized for exceptional research performance demonstrated by production of multiple highly cited papers, those that rank in the top 1% by citations for field and year in Web of Science.

• Royal Melbourne Hospital Excellence in Medicine Award (2018): Jeffrey Presneill• NHMRC Investigator Grants: Carol Hodgson and Emma Ridley• Visiting Professorship in Taiwan: David Pilcher• PhDs conferred: Aidan Burrell, Oana Tatucu, Ravi Tiruvoipati• Monash Faculty of Medicine, Nursing and Health Sciences Early Career Researcher Publication Prize -

The Jenny Keating Prize for Nursing and Allied Health: Emma Ridley

1716

Journal Publications 1. Abdelkarim H, Durie M, Bellomo R, Bergmeir C, Badawi

O, El-Khawas K, Pilcher D. A comparison of characteristics and outcomes of patients admitted to the ICU with asthma in Australia and New Zealand and United States. J Asthma 2019:epub.

2. Abraham J, Sinnollareddy MG, Roberts MS, Williams P, Peake SL, Lipman J, Roberts JA. Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. Int J Antimicrob Agents 2019;53:137-42.

3. Abrams D, Ferguson ND, Brochard L, Fan E, Mercat A, Combes A, Pellegrino V, Schmidt M, Slutsky AS, Brodie D. ECMO for ARDS: from salvage to standard of care? Lancet Respir Med 2019;7:108-10.

4. Abrams D, Schmidt M, Pham T, Beitler JR, Fan E, Goligher EC, McNamee JJ, Patroniti N, Wilcox ME, Combes A, Ferguson ND, McAuley DF, Pesenti A, Quintel M, Fraser J, Hodgson CL, Hough CL, Mercat A, Mueller T, Pellegrino V, Ranieri VM, Rowan K, Shekar K, Brochard L, Brodie D, International ECMO Network. Mechanical Ventilation for ARDS During Extracorporeal Life Support: Research and Practice. Am J Respir Crit Care Med 2019;epub.

5. Adaptive Platform Trials Coalition (ANZIC-RC: Webb S). Adaptive platform trials: definition, design, conduct and reporting considerations. Nat Rev Drug Discov 2019;18:797-807.

6. Al-Bassam W, Dade F, Bailey M, Eastwood G, Osawa E, Eyeington C, Anesty J, Yi G, Ralph J, Kakho N, Kurup V, Licari E, King EC, Knott C, Chimunda T, Smith J, Subramaniam A, Reddy M, Green C, Parkin G, Shehabi Y, Bellomo R. “Likely overassistance” during invasive pressure support ventilation in patients in the intensive care unit: a multicentre prospective observational study. Crit Care Resusc 2019;21:18-24.

7. Albrich L, Chapple LS, Nock A, Ridley EJ, Hickson M. Nutrition-related symptoms in adult survivors of critical illness when eating orally: a scoping review protocol. JBI Database System Rev Implement Rep 2019;epub.

8. Allen J, Orellana L, Jones D, Considine J, Currey J. Associations between patient and system characteristics and MET review within 48h of admission to a teaching hospital: A retrospective cohort study. Eur J Intern Med 2019;66:62-8.

9. Amaral A, Vincent JL, Rose L, Mikkelsen ME, Webb S, Ramos GV, Pinto R, Salluh J. An international perspective on the frequency, perception of utility, and quality of interprofessional rounds practices in intensive care units. J Crit Care 2019;55:28-34.

10. Anstey MH, Litton E, Jha N, Trevenen ML, Webb S, Mitchell IA. A comparison of the opinions of intensive care unit staff and family members of the treatment intensity received by patients admitted to an intensive care unit: A multicentre survey. Aust Crit Care 2019;32:378-82.

11. Anstey MH, Litton E, Trevenen ML, Thompson K, Webb S, Seppelt I, Mitchell IA. The prevalence of perceptions of mismatch between treatment intensity and achievable goals of care in the intensive care unit: a cross-sectional study. Intensive Care Med 2019;45:459-67.

12. Aubron C, Berteau F, Sparrow RL. Intravenous immunoglobulin for adjunctive treatment of severe infections in ICUs. Curr Opin Crit Care 2019;25:417-22.

13. Aubron C, McQuilten Z, Bailey M, Board J, Buhr H, Cartwright B, Dennis M, Hodgson C, Forrest P, McIlroy D, Murphy D, Murray L, Pellegrino V, Pilcher D, Sheldrake J, Tran H, Vallance S, Cooper DJ, endorsed by the International ECMO Network. Low-Dose Versus Therapeutic Anticoagulation in Patients on Extracorporeal Membrane Oxygenation: A Pilot Randomized Trial. Crit Care Med 2019;47:e563-71.

14. Aung M, Raith E, Williams E, Burrell AJ. Severe meningococcal serogroup W sepsis presenting as myocarditis: A case report and review of literature. J Intensive Care Soc 2019;20:182-6.

15. Australia and New Zealand Cardiac Arrest Outcome Determinants of ECMO Investigators, Jones D, Hodgson C, Eastwood G, Bellomo R, Pound G, Higgins A, Hilton A. The epidemiology of in-hospital cardiac arrests in Australia: a prospective multicentre observational study. Crit Care Resusc 2019;21:180-7.

16. Banakh I, Kung R, Gupta S, Matthiesson K, Tiruvoipati

R. Euglycemic diabetic ketoacidosis in association with dapagliflozin use after gastric sleeve surgery in a patient with type II diabetes mellitus. Clin Case Rep 2019;7:1087-90.

17. Baptista JP, Roberts JA, Udy AA. Augmented renal clearance: A real phenomenon with an uncertain cause. Anaesth Crit Care Pain Med 2019;38:335-6.

18. Begum H, Vishwanath S, Merenda M, Tacey M, Dean N, Elder E, Mureau M, Bezic R, Carter P, Cooter RD, Deva A, Earnest A, Higgs M, Klein H, Magnusson M, Moore C, Rakhorst H, Saunders C, Stark B, Hopper I. Defining Quality Indicators for Breast Device Surgery: Using Registries for Global Benchmarking. Plast Reconstr Surg Glob Open 2019;7:e2348.

19. Bhullar HK, Aung AK, Graudins L, Ihle J, Gin D, Cleland H, Mei Teh B. Upper airway involvement in Stevens-Johnson syndrome and toxic epidermal necrolysis. Burns 2019;epub.

20. Bitker L, Cutuli SL, Cioccari L, Osawa EA, Toh L, Luethi N, Young H, Peck L, Eastwood GM, Martensson J, Bellomo R. Sepsis uncouples serum C-peptide and insulin levels in critically ill patients with type 2 diabetes mellitus. Crit Care Resusc 2019;21:87-95.

21. Broman LM, Taccone FS, Lorusso R, Malfertheiner MV, Pappalardo F, Di Nardo M, Belliato M, Bembea MM, Barbaro RP, Diaz R, Grazioli L, Pellegrino V, Mendonca MH, Brodie D, Fan E, Bartlett RH, McMullan MM, Conrad SA. The ELSO Maastricht Treaty for ECLS Nomenclature: abbreviations for cannulation configuration in extracorporeal life support - a position paper of the Extracorporeal Life Support Organization. Crit Care 2019;23:36.

22. Brown AJ, Cutuli SL, Eastwood GM, Bitker L, Marsh P, Bellomo R. A pilot randomised controlled trial evaluating the pharmacodynamic effects of furosemide versus acetazolamide in critically ill patients. Crit Care Resusc 2019;21:258-64.

23. Burns KE, Haysom HE, Higgins AM, Waters N, Tahiri R, Rushford K, Dunstan T, Saxby K, Kaplan Z, Chunilal S, McQuilten ZK, Wood EM. A time-driven, activity-based costing methodology for determining the costs of red blood cell transfusion in patients with beta thalassaemia major. Transfus Med 2019;29:33-40.

24. Burrell AJC, Bennett V, Serra AL, Pellegrino VA, Romero L, Fan E, Brodie D, Cooper DJ, Kaye DM, Fraser JF, Hodgson CL. Venoarterial extracorporeal membrane oxygenation: A systematic review of selection criteria, outcome measures and definitions of complications. J Crit Care 2019;53:32-7.

25. Calzavacca P, Booth LC, Lankadeva YR, Bailey SR, Burrell LM, Bailey M, Bellomo R, May CN. Effects of Clonidine on the Cardiovascular, Renal, and Inflammatory Responses to Experimental Bacteremia. Shock 2019;51:348-55.

26. Canet E, Amjad S, Robbins R, Lewis J, Matalanis M, Jones D, Bellomo R. Differential clinical characteristics, management and outcome of delirium among ward compared with intensive care unit patients. Intern Med J 2019;49:1496-504.

27. Capell EL, Tipping CJ, Hodgson CL. Barriers to implementing expert safety recommendations for early mobilisation in intensive care unit during mechanical ventilation: A prospective observational study. Aust Crit Care 2019;32:185-90.

28. Casaer MP, Bellomo R. Micronutrient deficiency in critical illness: an invisible foe? Intensive Care Med 2019;45:1136-9.

29. Chan MJ, Lucchetta L, Cutuli S, Eyeington C, Glassford NJ, Martensson J, Angelopoulos P, Matalanis G, Weinberg L, Eastwood GM, Bellomo R. A Pilot Randomized Controlled Study of Mild Hypercapnia During Cardiac Surgery With Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth 2019;33:2968-78.

30. Chapple LS, Weinel L, Ridley EJ, Jones D, Chapman MJ, Peake SL. Clinical Sequelae From Overfeeding in Enterally Fed Critically Ill Adults: Where Is the Evidence? JPEN J Parenter Enteral Nutr 2019;epub.

31. Cioccari L, Luethi N, Glassford NJ, Bellomo R. The normal cardiac index in older healthy individuals: a scoping review. Crit Care Resusc 2019;21:9-17.

32. Clucas DB, Fox LC, Wood EM, Hong FS, Gibson J, Bajel A, Szer J, Blombery P, McQuilten ZK, Hiwase D, Firkin F, Cole-Sinclair MF, Australian Aplastic Anaemia Registry Steering Committee. Revisiting acquired aplastic anaemia: current concepts in

Publications Publications (continued)

Journal Publications (continued)diagnosis and management. Intern Med J 2019;49:152-9.

33. Cooper DJ, Nichol AD, McArthur C. Prophylactic Hypothermia for Severe Traumatic Brain Injury-Reply. JAMA 2019;321:1726.

34. Corley A, Lye I, Lavana JD, Ahuja A, Anstey CM, Jarrett P, Haisz E, Parke R, Pellegrino V, Buscher H, Fraser JF, ECMO PP Study Investigators. Nosocomial infection prevalence in patients undergoing extracorporeal membrane oxygenation (ECMO): protocol for a point prevalence study across Australia and New Zealand. BMJ Open 2019;9:e029293.

35. Cosgrave D, Vencken S, Galligan M, McGuinness S, Soukhin E, McMullan V, Hussain R, Conlon N, Doran P, Nichol A. The effect of a low-dose naloxone infusion on the incidence of respiratory depression after intrathecal morphine administration for major open hepatobiliary surgery: a randomised controlled trial. Anaesthesia 2019;epub.

36. Cudini D, Smith K, Bernard S, Stephenson M, Andrew E, Cameron P, Lum M, Udy A, ARISE Investigators. Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients? Emerg Med Australas 2019;31:669-72.

37. Dankiewicz J, Cronberg T, Lilja G, Jakobsen JC, Belohlavek J, Callaway C, Cariou A, Eastwood G, Erlinge D, Hovdenes J, Joannidis M, Kirkegaard H, Kuiper M, Levin H, Morgan MPG, Nichol AD, Nordberg P, Oddo M, Pelosi P, Rylander C, Saxena M, Storm C, Taccone F, Ullen S, Wise MP, Young P, Friberg H, Nielsen N. Targeted hypothermia versus targeted Normothermia after out-of-hospital cardiac arrest (TTM2): A randomized clinical trial-Rationale and design. Am Heart J 2019;217:23-31.

38. Darvall JN, Bellomo R, Paul E, Subramaniam A, Santamaria JD, Bagshaw SM, Rai S, Hubbard RE, Pilcher D. Frailty in very old critically ill patients in Australia and New Zealand: a population-based cohort study. Med J Aust 2019;211:318-23.

39. Darvall JN, Boonstra T, Norman J, Murphy D, Bailey M, Iwashyna TJ, Bagshaw SM, Bellomo R. Persistent critical illness: baseline characteristics, intensive care course, and cause of death. Crit Care Resusc 2019;21:110-8.

40. Darvall JN, Boonstra T, Norman J, Murphy D, Bailey M, Iwashyna TJ, Bagshaw SM, Bellomo R. Retrospective frailty determination in critical illness from a review of the intensive care unit clinical record. Anaesth Intensive Care 2019;47:343-8.

41. Das A, Anstey M, Bass F, Blythe D, Buhr H, Campbell L, Davda A, Delaney A, Gattas D, Green C, Ferrier J, Hammond N, Palermo A, Pellicano S, Phillips M, Regli A, Roberts B, Ross-King M, Saroode V, Simpson S, Spiller S, Sullivan K, Tiruvoipati R, Haren FV, Waterson S, Yaw LK, Litton E. Internet health information use by surrogate decision makers of patients admitted to the intensive care unit: a multicentre survey. Crit Care Resusc 2019;21:305-10.

42. Delaney A, Finnis M, Bellomo R, Udy A, Jones D, Keijzers G, MacDonald S, Peake S. Initiation of vasopressor infusions via peripheral versus central access in patients with early septic shock: A retrospective cohort study. Emerg Med Australas 2019;epub.

43. Eastwood GM, Chan MJ, Peck L, Young H, Martensson J, Glassford NJ, Kagaya H, Suzuki S, Galvin S, Matalanis G, Bellomo R. Conservative versus conventional oxygen therapy for cardiac surgical patients: A before-and-after study. Anaesth Intensive Care 2019;47:175-82.

44. Eastwood GM, Nielsen N, Nichol AD, Skrifvars MB, French C, Bellomo R. Reported practice of temperature adjustment (alpha-stat v pH-stat) for arterial blood gases measurement among investigators from two major cardiac arrest trials. Crit Care Resusc 2019;21:69-71.

45. Estcourt LJ, McQuilten Z, Powter G, Dyer C, Curnow E, Wood EM, Stanworth SJ, TREATT Trial Collaboration. The TREATT Trial (TRial to EvaluAte Tranexamic acid therapy in Thrombocytopenia): safety and efficacy of tranexamic acid in patients with haematological malignancies with severe thrombocytopenia: study protocol for a double-blind randomised controlled trial. Trials 2019;20:592.

46. Evans LR, Jones J, Lee HQ, Gantner D, Jaison A, Matthew J, Fitzgerald MC, Rosenfeld JV, Hunn MK, Tee JW. Prognosis of Acute Subdural Hematoma in the Elderly: A Systematic Review. J Neurotrauma 2019;36:517-22.

47. Eyeington CT, Ancona P, Osawa EA, Cutuli SL, Eastwood GM, Bellomo R. Modern technology-derived normative values for cerebral tissue oxygen saturation in adults. Anaesth Intensive Care 2019;47:69-75.

48. Eyeington CT, Lloyd-Donald P, Chan MJ, Eastwood GM, Young H, Peck L, Jones DA, Bellomo R. Rapid response team review of hemodynamically unstable ward patients: The accuracy of cardiac index assessment. J Crit Care 2019;49:187-92.

49. Eyeington CT, Lloyd-Donald P, Chan MJ, Eastwood GM, Young H, Peck L, Marhoon N, Jones DA, Bellomo R. Non-invasive continuous haemodynamic monitoring and response to intervention in haemodynamically unstable patients during rapid response team review. Resuscitation 2019;143:124-33.

50. Fujii T, Belletti A, Carr A, Furukawa TA, Luethi N, Putzu A, Sartini C, Salanti G, Tsujimoto Y, Udy AA, Young PJ, Bellomo R. Vitamin C therapy for patients with sepsis or septic shock: a protocol for a systematic review and a network meta-analysis. BMJ Open 2019;9:e033458.

51. Fujii T, Sato T, Uchino S, Doi K, Iwami T, Kawamura T, Jakid Study Group. Human atrial natriuretic peptide for acute kidney injury in adult critically ill patients: A multicenter prospective observational study. J Crit Care 2019;51:229-35.

52. Fujii T, Udy A, Licari E, Romero L, Bellomo R. Sodium bicarbonate therapy for critically ill patients with metabolic acidosis: A scoping and a systematic review. J Crit Care 2019;51:184-91.

53. Fujii T, Udy AA, Deane AM, Luethi N, Bailey M, Eastwood GM, Frei D, French C, Orford N, Shehabi Y, Young PJ, Bellomo R, VITAMINS Trial Investigators. Vitamin C, Hydrocortisone and Thiamine in Patients with Septic Shock (VITAMINS) trial: study protocol and statistical analysis plan. Crit Care Resusc 2019;21:119-25.

54. Fujii T, Udy AA, Venkatesh B. Comparing apples and oranges: the vasoactive effects of hydrocortisone and studies investigating high dose vitamin C combination therapy in septic shock. Crit Care Resusc 2019;21:152-5.

55. Gal M, Gobat N, Francis NA, Hood K, Butler CC, Bielicki J, Fraaij PL, Sharland M, Jarvis J, van Rossum AMC, Heikkinen T, Martinon-Torres F, Herberg J, Watkins A, Webb SAR, Moore R, Sukumar P, Nichol A. Priority Needs for Conducting Pandemic-relevant Clinical Research With Children in Europe: A Consensus Study With Pediatric Clinician-researchers. Pediatr Infect Dis J 2019;38:e82-6.

56. George ES, Marshall S, Mayr HL, Trakman GL, Tatucu-Babet OA, Lassemillante AM, Bramley A, Reddy AJ, Forsyth A, Tierney AC, Thomas CJ, Itsiopoulos C, Marx W. The effect of high-polyphenol extra virgin olive oil on cardiovascular risk factors: A systematic review and meta-analysis. Crit Rev Food Sci Nutr 2019;59:2772-95.

57. Gershengorn HB, Pilcher DV, Litton E, Anstey M, Garland A, Wunsch H. Association Between Consecutive Days Worked by Intensivists and Outcomes for Critically Ill Patients. Crit Care Med 2019;epub.

58. Gilder E, Parke RL, Jull A, Australian and New Zealand Intensive Care Society Clinical Trials Group, The George Institute for Global Health. Endotracheal suction in intensive care: A point prevalence study of current practice in New Zealand and Australia. Aust Crit Care 2019;32:112-5.

59. Gluck S, Summers MJ, Finnis ME, Andrawos A, Goddard TP, Hodgson CL, Iwashyna TJ, Deane AM. An observational study investigating the use of patient-owned technology to quantify physical activity in survivors of critical illness. Aust Crit Care 2019;epub.

60. Gobat N, Amuasi J, Yazdanpanah Y, Sigfid L, Davies H, Byrne JP, Carson G, Butler C, Nichol A, Goossens H. Advancing preparedness for clinical research during infectious disease epidemics. ERJ Open Res 2019;5.

61. Gobat N, Butler CC, Mollison J, Francis NA, Gal M, Harris V, Webb SAR, Byrne JP, Watkins A, Sukumar P, Hood K, Nichol A. What the public think about participation in medical research during an influenza pandemic: an international cross-sectional survey. Public Health 2019;177:80-94.

62. Gouldthorpe OT, Pilcher DV, Bellomo R, Udy AA. Prevalence of low-normal body temperatures and use of active warming in emergency department patients presenting with severe infection. Crit Care Resusc 2019;21:96-101.

1918

Publications (continued)

Journal Publications (continued)63. Green C, Bonavia W, Toh C, Tiruvoipati R. Prediction of ICU

Delirium: Validation of Current Delirium Predictive Models in Routine Clinical Practice. Crit Care Med 2019;47:428-35.

64. Gupta S, Tiruvoipati R, Wang WC, Green C, Botha J. How do intensivists treat their patients, their loved ones and themselves? Results of a survey of intensivists facing an evolving hypothetical clinical scenario. N Z Med J 2019;132:13-22.

65. Haines KJ, McPeake J, Hibbert E, Boehm LM, Aparanji K, Bakhru RN, Bastin AJ, Beesley SJ, Beveridge L, Butcher BW, Drumright K, Eaton TL, Farley T, Firshman P, Fritschle A, Holdsworth C, Hope AA, Johnson A, Kenes MT, Khan BA, Kloos JA, Kross EK, Mactavish P, Meyer J, Montgomery-Yates A, Quasim T, Saft HL, Slack A, Stollings J, Weinhouse G, Whitten J, Netzer G, Hopkins RO, Mikkelsen ME, Iwashyna TJ, Sevin CM. Enablers and Barriers to Implementing ICU Follow-Up Clinics and Peer Support Groups Following Critical Illness: The Thrive Collaboratives. Crit Care Med 2019;47:1194-200.

66. Haines KJ, Sevin CM, Hibbert E, Boehm LM, Aparanji K, Bakhru RN, Bastin AJ, Beesley SJ, Butcher BW, Drumright K, Eaton TL, Farley T, Firshman P, Fritschle A, Holdsworth C, Hope AA, Johnson A, Kenes MT, Khan BA, Kloos JA, Kross EK, MacLeod-Smith BJ, Mactavish P, Meyer J, Montgomery-Yates A, Quasim T, Saft HL, Slack A, Stollings J, Weinhouse G, Whitten J, Netzer G, Hopkins RO, Mikkelsen ME, Iwashyna TJ, McPeake J. Key mechanisms by which post-ICU activities can improve in-ICU care: results of the international THRIVE collaboratives. Intensive Care Med 2019;45:939-47.

67. Harrois A, Anstey JR, Taccone FS, Udy AA, Citerio G, Duranteau J, Ichai C, Badenes R, Prowle JR, Ercole A, Oddo M, Schneider A, van der Jagt M, Wolf S, Helbok R, Nelson DW, Skrifvars MB, Cooper DJ, Bellomo R, TBI Collaborative. Serum sodium and intracranial pressure changes after desmopressin therapy in severe traumatic brain injury patients: a multi-centre cohort study. Ann Intensive Care 2019;9:99.

68. Hawryluk GWJ, Aguilera S, Buki A, Bulger E, Citerio G, Cooper DJ, Arrastia RD, Diringer M, Figaji A, Gao G, Geocadin R, Ghajar J, Harris O, Hoffer A, Hutchinson P, Joseph M, Kitagawa R, Manley G, Mayer S, Menon DK, Meyfroidt G, Michael DB, Oddo M, Okonkwo D, Patel M, Robertson C, Rosenfeld JV, Rubiano AM, Sahuquillo J, Servadei F, Shutter L, Stein D, Stocchetti N, Taccone FS, Timmons S, Tsai E, Ullman JS, Vespa P, Videtta W, Wright DW, Zammit C, Chesnut RM. A management algorithm for patients with intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC). Intensive Care Med 2019;45:1783-94.

69. Hay T, Deane AM, Rechnitzer T, Fetterplace K, Reilly R, Ankravs M, Bailey M, Fazio T, Anstey J, D’Costa R, Presneill JJ, MacIsaac CM, Bellomo R. The hospital-based evaluation of laxative prophylaxis in ICU (HELP-ICU): A pilot cluster-crossover randomized clinical trial. J Crit Care 2019;52:86-91.

70. Hernandez G, Bellomo R, Bakker J. The ten pitfalls of lactate clearance in sepsis. Intensive Care Med 2019;45:82-5.

71. Hessels L, Coulson TG, Seevanayagam S, Young P, Pilcher D, Marhoon N, Bellomo R. Development and Validation of a Score to Identify Cardiac Surgery Patients at High Risk of Prolonged Mechanical Ventilation. J Cardiothorac Vasc Anesth 2019;33:2709-16.

72. Hicks P, Huckson S, Fenney E, Leggett I, Pilcher D, Litton E. The financial cost of intensive care in Australia: a multicentre registry study. Med J Aust 2019;211:324-5.

73. Higgins AM, Peake SL, Bellomo R, Cooper DJ, Delaney A, Harris AH, Howe BD, Nichol AD, Webb SA, Williams PJ, Australasian Resuscitation in Sepsis Evaluation Investigators, ANZICS Clinical Trials Group. Quality of Life and 1-Year Survival in Patients With Early Septic Shock: Long-Term Follow-Up of the Australasian Resuscitation in Sepsis Evaluation Trial. Crit Care Med 2019;47:765-73.

74. Ho PJ, Moore EM, McQuilten ZK, Wellard C, Bergin K, Augustson B, Blacklock H, Harrison SJ, Horvath N, King T, Mollee P, Quach H, Reid C, Rosengarten B, Walker P, Wood EM, Spencer A. Renal Impairment at Diagnosis in Myeloma: Patient Characteristics, Treatment, and Impact on Outcomes. Results From the Australia and New Zealand Myeloma and Related Diseases Registry. Clin Lymphoma Myeloma Leuk

2019;19:e415-24.75. Hodgson CL, Brodie D. Comparing Apples to Oranges?

Anesthesiology 2019;130:528-9.76. Hodgson CL, Burrell AJC, Engeler DM, Pellegrino VA, Brodie D,

Fan E, International ECMO Network. Core Outcome Measures for Research in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation for Acute Respiratory or Cardiac Failure: An International, Multidisciplinary, Modified Delphi Consensus Study. Crit Care Med 2019;47:1557-63.

77. Hodgson CL, Cooper DJ, Arabi Y, King V, Bersten A, Bihari S, Brickell K, Davies A, Fahey C, Fraser J, McGuinness S, Murray L, Parke R, Paul E, Tuxen D, Vallance S, Young M, Nichol A. Maximal Recruitment Open Lung Ventilation in Acute Respiratory Distress Syndrome (PHARLAP). A Phase II, Multicenter Randomized Controlled Clinical Trial. Am J Respir Crit Care Med 2019;200:1363-72.

78. Holley AD, Reade MC, Lipman J, Delaney A, Udy A, Lee R, Litton E, Cheung W, Turner A, Garside T, Macken L, Reddi B, Kol M, Kazemi A, Shah A, Townsend S, Cohen J. Survey of critical care practice in Australian and New Zealand burn referral centres. Crit Care Resusc 2019;21:303-4.

79. Hudson EP, Collie JT, Fujii T, Luethi N, Udy AA, Doherty S, Eastwood G, Yanase F, Naorungroj T, Bitker L, Abdelhamid YA, Greaves RF, Deane AM, Bellomo R. Pharmacokinetic data support 6-hourly dosing of intravenous vitamin C to critically ill patients with septic shock. Crit Care Resusc 2019;21:236-42.

80. Husain-Syed F, Ferrari F, Sharma A, Hinna Danesi T, Bezerra P, Lopez-Giacoman S, Samoni S, de Cal M, Corradi V, Virzi GM, De Rosa S, Mucino Bermejo MJ, Estremadoyro C, Villa G, Zaragoza JJ, Caprara C, Brocca A, Birk HW, Walmrath HD, Seeger W, Nalesso F, Zanella M, Brendolan A, Giavarina D, Salvador L, Bellomo R, Rosner MH, Kellum JA, Ronco C. Persistent decrease of renal functional reserve in patients after cardiac surgery-associated acute kidney injury despite clinical recovery. Nephrol Dial Transplant 2019;34:308-17.

81. Hutchinson PJ, Kolias AG, Tajsic T, Adeleye A, Aklilu AT, Apriawan T, Bajamal AH, Barthelemy EJ, Devi BI, Bhat D, Bulters D, Chesnut R, Citerio G, Cooper DJ, Czosnyka M, Edem I, El-Ghandour NMF, Figaji A, Fountas KN, Gallagher C, Hawryluk GWJ, Iaccarino C, Joseph M, Khan T, Laeke T, Levchenko O, Liu B, Liu W, Maas A, Manley GT, Manson P, Mazzeo AT, Menon DK, Michael DB, Muehlschlegel S, Okonkwo DO, Park KB, Rosenfeld JV, Rosseau G, Rubiano AM, Shabani HK, Stocchetti N, Timmons SD, Timofeev I, Uff C, Ullman JS, Valadka A, Waran V, Wells A, Wilson MH, Servadei F. Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury : Consensus statement. Acta Neurochir (Wien) 2019;161:1261-74.

82. ICU-ROX Investigators, the Australian and New Zealand Intensive Care Society Clinical Trials Group, Mackle D, Bellomo R, Bailey M, Beasley R, Deane A, Eastwood G, Finfer S, Freebairn R, King V, Linke N, Litton E, McArthur C, McGuinness S, Panwar R, Young P. Conservative Oxygen Therapy during Mechanical Ventilation in the ICU. N Engl J Med 2019;epub.

83. Ihle J, Burrell A. Confirmation of brain death on VA-ECMO should mandate simultaneous distal arterial and post-oxygenator blood gas sampling. Intensive Care Med 2019;45:1165-6.

84. Irving A, Higgins A, Ady B, Bellomo R, Cooper DJ, French C, Gantner D, Harris A, Irving DO, Murray L, Nichol A, Petrie D, McQuilten ZK, TRANSFUSE Investigators, ANZICS Clinical Trials Group. Fresh Red Cells for Transfusion in Critically Ill Adults: An Economic Evaluation of the Standard Issue Transfusion Versus Fresher Red-Cell Use in Intensive Care (TRANSFUSE) Clinical Trial. Crit Care Med 2019;47:e572-9.

85. Irving AH, Harris A, Petrie D, Higgins A, Smith J, McQuilten ZK. Impact of patient blood management guidelines on blood transfusions and patient outcomes during cardiac surgery. J Thorac Cardiovasc Surg 2019;epub.

86. Jamadar SD, Sforazzini F, Raniga P, Ferris NJ, Paton B, Bailey MJ, Brodtmann A, Yates PA, Donnan GA, Ward SA, Woods RL, Storey E, McNeil JJ, Egan GF, ASPREE Investigator Group. Sexual Dimorphism of Resting-State Network Connectivity in Healthy Ageing. J Gerontol B Psychol Sci Soc Sci 2019;74:1121-31.


87. Jeffcote T, Foong M, Gold G, Glassford N, Robbins R, Iwashyna TJ, Darvall J, Bagshaw SM, Bellomo R. Patient characteristics, ICU-specific supports, complications, and outcomes of persistent critical illness. J Crit Care 2019;54:250-5.

88. Jones D, Matalanis G, Martensson J, Robbins R, Shaw M, Seevanayagam S, Cowie D, Bellomo R. Predictors and Outcomes of Cardiac Surgery-Associated Delirium. A Single Centre Retrospective Cohort Study. Heart Lung Circ 2019;28:455-63.

89. Karalapillai D, Weinberg L, Peyton P, Ellard L, Hu R, Pearce B, Tan C, Story D, M OD, Hamilton P, Oughton C, Galtieri J, Wilson A, Neto AS, Eastwood G, Bellomo R, Jones DA. Low tidal volume ventilation during anaesthesia for major surgery: protocol and statistical analysis plan. Crit Care Resusc 2019;21:243-50.

90. Keijzers G, Macdonald SP, Udy AA, Arendts G, Bailey M, Bellomo R, Blecher GE, Burcham J, Delaney A, Coggins AR, Fatovich DM, Fraser JF, Harley A, Jones P, Kinnear F, May K, Peake S, Taylor DM, Williams J, Williams P, ARISE Fluids Study Group. The Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In Emergency Department Sepsis, a multicentre observational study (ARISE FLUIDS observational study): Rationale, methods and analysis plan. Emerg Med Australas 2019;31:90-6.

91. Kennedy L, Wrigley S, Kennedy M, Pellegrino V. Extracorporeal membrane oxygenation retrieval factors and survival to intensive care unit discharge. Emerg Med Australas 2019;31:280-2.

92. Ket SN, Sparrow RL, McQuilten ZK, Tacey M, Gibson PR, Brown GJ, Wood EM. Clinical coding data algorithm to categorize type of gastrointestinal bleeding as a primary reason for massive transfusion: results from the Australian and New Zealand Massive Transfusion Registry. Vox Sang 2019;114:853-60.

93. Knott RJ, Harris A, Higgins A, Nichol A, French C, Little L, Haddad S, Presneill J, Arabi Y, Bailey M, Cooper DJ, Duranteau J, Huet O, Mak A, McArthur C, Pettila V, Skrifvars MB, Vallance S, Varma D, Wills J, Bellomo R. Cost-Effectiveness of Erythropoietin in Traumatic Brain Injury: A Multinational Trial-Based Economic Analysis. J Neurotrauma 2019;36:2541-8.

94. Kotani Y, Fujii T, Uchino S, Doi K, Jakid Study Group. Modification of sequential organ failure assessment score using acute kidney injury classification. J Crit Care 2019;51:198-203.

95. Lambell K, Peake S, Ridley E. Nutrition management of obese critically ill patients: More research is urgently needed. Clin Nutr 2019;38:1957.

96. Landoni G, Pieri M, Young PJ, Bellomo R. Why do multicenter randomized controlled trials not confirm the positive findings of single center randomized controlled trials in acute care? Minerva Anestesiol 2019;85:194-200.

97. Lang J, Haines K. Clinimetrics: Appraisal of Guidelines, Research and Evaluation II. J Physiother 2019;65:176.

98. Lankadeva YR, Kosaka J, Iguchi N, Evans RG, Booth LC, Bellomo R, May CN. Effects of Fluid Bolus Therapy on Renal Perfusion, Oxygenation, and Function in Early Experimental Septic Kidney Injury. Crit Care Med 2019;47:e36-43.

99. Lessard Bonaventure P, Lauzier F, Zarychanski R, Boutin A, Shemilt M, Saxena M, Zolfagari P, Griesdale D, Menon DK, Stanworth S, English S, Chasse M, Fergusson DA, Moore L, Kramer A, Robitaille A, Myburgh J, Cooper J, Hutchinson P, Turgeon AF, Canadian Critical Care Trials Group, Canadian Traumatic Brain Injury Research Consortium. Red blood cell transfusion in critically ill patients with traumatic brain injury: an international survey of physicians’ attitudes. Can J Anaesth 2019;66:1038-48.

100. Leung J, Ridley EJ, Cleland H, Ihle JF, Paul E, King SJ. Predictive energy equations are inaccurate for determining energy expenditure in adult burn injury: a retrospective observational study. ANZ J Surg 2019;89:578-83.

101. Levkovich BJ, Bingham G, Hopkins RE, Jones D, Cooper DJJ, Kirkpatrick CM, Dooley MJ. An Observational Analysis of Medication Use During 5,727 Medical Emergency Team Activations at a Tertiary Referral Hospital. Jt Comm J Qual Patient Saf 2019;45:502-8.

102. Levkovich BJ, Bingham G, Jones D, Kirkpatrick CM, Cooper DJJ, Dooley MJ. Understanding how medications contribute to clinical deterioration and are used in rapid response systems: A comprehensive scoping review. Aust Crit Care 2019;32:256-

72.103. Levkovich BJ, Bingham G, Orosz J, Cooper DJJ, Kirkpatrick CM,

Dooley MJ, Jones DA. The frequency and nature of clinician identified medication-related rapid response system calls. Resuscitation 2019;145:75-8.

104. Lim MS, Indran T, Cummins A, Bennett A, Wood E, Brown S, McQuilten Z, Tran H, Epi MC, Chan NC, Chunilal S. Utility of a Nurse-Led Pathway for Patients with Acute Venous Thromboembolism Discharged on Rivaroxaban: A Prospective Cohort Study. Semin Thromb Hemost 2019;45:187-95.

105. Lucchetta L, Kwan TN, Kosaka J, Tanaka A, Eastwood GM, Chan M, Martensson J, May CN, Bellomo R. Carotid artery and cerebral blood flow during experimental cardiopulmonary resuscitation: A systematic review of the literature. Resuscitation 2019;138:46-52.

106. Luethi N, Cioccari L, Eastwood G, Biesenbach P, Morgan R, Sprogis S, Young H, Peck L, Knee Chong C, Moore S, Moon K, Ekinci EI, Deane AM, Bellomo R, Martensson J. Hospital-acquired complications in intensive care unit patients with diabetes: A before-and-after study of a conventional versus liberal glucose control protocol. Acta Anaesthesiol Scand 2019;63:761-8.

107. Magee F, Wilson A, Bailey MJ, Pilcher D, Secombe PJ, Young P, Bellomo R. Trauma-related admissions to intensive care units in Australia: the influence of Indigenous status on outcomes. Med J Aust 2019;210:493-8.

108. Majeed A, Majumdar A, Bailey M, Kemp W, Bellomo R, Pilcher D, Roberts SK. Declining Mortality of Cirrhotic Variceal Bleeding Requiring Admission to Intensive Care: A Binational Cohort Study. Crit Care Med 2019;47:1317-23.

109. Majumdar A, Roberts SK, Pilcher D. Are liver transplant centres critical for the critically ill patient with cirrhosis? J Hepatol 2019;71:637-8.

110. Marasco SF, Farag J, Kure C, Summerhayes R, Bailey M, McGiffin D. A real-life experience with HeartMate III. J Card Surg 2019;34:1031-6.

111. Marasco SF, Martin K, Niggemeyer L, Summerhayes R, Fitzgerald M, Bailey M. Impact of rib fixation on quality of life after major trauma with multiple rib fractures. Injury 2019;50:119-24.

112. McFall A, Peake SL, Williams PJ. Weight and height documentation: Does ICU measure up? Aust Crit Care 2019;32:314-8.

113. McIntyre T, Taylor C, Bailey M, Jones D. Differences in the characteristics, treatment, and outcomes of patient groups reviewed by intensive care liaison nurses in Australia: A multicentre prospective study. Aust Crit Care 2019;32:403-9.

114. McLeod C, Norman R, Litton E, Saville BR, Webb S, Snelling TL. Choosing primary endpoints for clinical trials of health care interventions. Contemp Clin Trials Commun 2019;16:100486.

115. McLeod C, Norman R, Schultz A, Mascaro S, Webb S, Snelling T. Discrete choice experiment to evaluate preferences of patients with cystic fibrosis among alternative treatment-related health outcomes: a protocol. BMJ Open 2019;9:e030348.

116. McMahon BA, Galligan M, Redahan L, Martin T, Meaney E, Cotter EJ, Murphy N, Hannon C, Doran P, Marsh B, Nichol A, Murray PT. Biomarker Predictors of Adverse Acute Kidney Injury Outcomes in Critically Ill Patients: The Dublin Acute Biomarker Group Evaluation Study. Am J Nephrol 2019;50:19-28.

117. McPeake J, Hirshberg EL, Christie LM, Drumright K, Haines K, Hough CL, Meyer J, Wade D, Andrews A, Bakhru R, Bates S, Barwise JA, Bastarache J, Beesley SJ, Boehm LM, Brown S, Clay AS, Firshman P, Greenberg S, Harris W, Hill C, Hodgson C, Holdsworth C, Hope AA, Hopkins RO, Howell DCJ, Janssen A, Jackson JC, Johnson A, Kross EK, Lamas D, MacLeod-Smith B, Mandel R, Marshall J, Mikkelsen ME, Nackino M, Quasim T, Sevin CM, Slack A, Spurr R, Still M, Thompson C, Weinhouse G, Wilcox ME, Iwashyna TJ. Models of Peer Support to Remediate Post-Intensive Care Syndrome: A Report Developed by the Society of Critical Care Medicine Thrive International Peer Support Collaborative. Crit Care Med 2019;47:e21-7.

118. McPeake J, Mikkelsen ME, Quasim T, Hibbert E, Cannon P, Shaw M, Ankori J, Iwashyna TJ, Haines KJ. Return to Employment after Critical Illness and Its Association with Psychosocial

Journal Publications (continued)

2120

Outcomes. A Systematic Review and Meta-Analysis. Ann Am Thorac Soc 2019;16:1304-11.

119. McQuilten ZK, Cooper DJ. Age of Red Blood Cells for Transfusion in Critically Ill Pediatric Patients. JAMA 2019;322:2175-6.

120. McQuilten ZK, Higgins AM, Burns K, Chunilal S, Dunstan T, Haysom HE, Kaplan Z, Rushford K, Saxby K, Tahiri R, Waters N, Wood EM. The cost of blood: a study of the total cost of red blood cell transfusion in patients with beta-thalassemia using time-driven activity-based costing. Transfusion 2019;59:3386-95.

121. Milnes S, Corke C, Orford NR, Bailey M, Savulescu J, Wilkinson D. Patient values informing medical treatment: a pilot community and advance care planning survey. BMJ Support Palliat Care 2019;9:e23.

122. Milross LA, O’Donnell TG, Bucknall TK, Pilcher DV, Ihle JF. Exploring staff perceptions of organ donation after circulatory death. Aust Crit Care 2019;epub.

123. Mitra B, Roman C, Charters KE, O’Reilly G, Gantner D, Cameron PA. Lactate, bicarbonate and anion gap for evaluation of patients presenting with sepsis to the emergency department: A prospective cohort study. Emerg Med Australas 2019;epub.

124. Morganti-Kossmann MC, Semple BD, Hellewell SC, Bye N, Ziebell JM. The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments. Acta Neuropathol 2019;137:731-55.

125. Murthy S, Carson G, Horby P, Merson L, Webb S. Clinical research networks and assessing pandemic severity. Lancet Glob Health 2019;7:e33.

126. Myles PS, Smith JA, Kasza J, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussieres JS, McGuinness S, Byrne K, Chan MTV, Landoni G, Wallace S, Forbes A, ATACAS Investigators, the ANZCA Clinical Trials Network. Tranexamic acid in coronary artery surgery: One-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) trial. J Thorac Cardiovasc Surg 2019;157:644-52 e9.

127. Myles PS, Smith JA, Kasza J, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussieres JS, McGuinness S, Chan MTV, Wallace S, Forbes A, ATACAS Investigators, the ANZCA Clinical Trials Network. Aspirin in coronary artery surgery: 1-year results of the Aspirin and Tranexamic Acid for Coronary Artery Surgery trial. J Thorac Cardiovasc Surg 2019;157:633-40.

128. Ng SY, Phua J, Wong YL, Kalyanasundaram G, Mukhopadhyay A, Lim D, Chia N, Ho BCH, Bailey MJ, Shehabi Y, Ti LK. Singapore SPICE: Sedation Practices in Intensive Care Evaluation in Singapore - a prospective cohort study of the public healthcare system. Singapore Med J 2019;epub.

129. O’Brien Z, Cass A, Cole L, Finfer S, Gallagher M, McArthur C, McGuiness S, Myburgh J, Bellomo R, Martensson J. Sex and mortality in septic severe acute kidney injury. J Crit Care 2019;49:70-6.

130. Orford NR. What is an intensive care specialist? Med J Aust 2019;211:312-3.

131. Orford NR, Milnes S, Simpson N, Keely G, Elderkin T, Bone A, Martin P, Bellomo R, Bailey M, Corke C. Effect of communication skills training on outcomes in critically ill patients with life-limiting illness referred for intensive care management: a before-and-after study. BMJ Support Palliat Care 2019;9:e21.

132. Orford NR, Pasco JA, Kotowicz MA. Osteoporosis and the Critically Ill Patient. Crit Care Clin 2019;35:301-13.

133. Osawa EA, Cutuli SL, Bitker L, Canet E, Cioccari L, Iguchi N, Lankadeva YR, Eastwood GM, Evans RG, May CN, Bellomo R. Effect of Furosemide on Urinary Oxygenation in Patients with Septic Shock. Blood Purif 2019;48:336-45.

134. Pappacena S, Bailey M, Cabrini L, Landoni G, Udy A, Pilcher DV, Young P, Bellomo R. Early dysglycemia and mortality in traumatic brain injury and subarachnoid hemorrhage. Minerva Anestesiol 2019;85:830-9.

135. Peake SL, Chapman MJ, TARGET Investigators. Energy-Dense versus Routine Enteral Nutrition in the Critically Ill. N Engl J Med 2019;380:499-500.

136. Perner A, Bellomo R, Moller MH. Is research from databases

reliable? No. Intensive Care Med 2019;45:115-7.137. Phillips ML, Kuruvilla V, Bailey M. Implementation of the

Critical Care Pain Observation Tool increases the frequency of pain assessment for noncommunicative ICU patients. Aust Crit Care 2019;32:367-72.

138. Pilcher D, Huckson S, Hicks P. Sepsis incidence and mortality are underestimated in Australian intensive care unit administrative data. Med J Aust 2019;210:188- e1.

139. Poole AP, Anstey J, Bellomo R, Biradar V, Deane AM, Finfer SR, Finnis ME, French CJ, Kar P, Kruger PS, Maiden MJ, Martensson J, McArthur CJ, McGuinness SP, Secombe PJ, Tobin AE, Udy AA, Eastwood GM. Opinions and practices of blood glucose control in critically ill patients with pre-existing type 2 diabetes in Australian and New Zealand intensive care units. Aust Crit Care 2019;32:361-5.

140. Porteous J, Cioccari L, Ancona P, Osawa E, Jones K, Gow P, Angus P, Warrillow S, Bellomo R. Outcome of Acetaminophen-Induced Acute Liver Failure Managed Without Intracranial Pressure Monitoring or Transplantation. Liver Transpl 2019;25:35-44.

141. Prescott HC, Iwashyna TJ, Blackwood B, Calandra T, Chlan LL, Choong K, Connolly B, Dark P, Ferrucci L, Finfer S, Girard TD, Hodgson C, Hopkins RO, Hough CL, Jackson JC, Machado FR, Marshall JC, Misak C, Needham DM, Panigrahi P, Reinhart K, Yende S, Zafonte R, Rowan KM, Angus DC. Understanding and Enhancing Sepsis Survivorship. Priorities for Research and Practice. Am J Respir Crit Care Med 2019;200:972-81.

142. Ragg M, Ragg J, Milnes S, Bailey M, Orford N. Patients with life-limiting illness presenting to the emergency department. Emerg Med Australas 2019;epub.

143. Ramos JGR, Ranzani OT, Perondi B, Dias RD, Jones D, Carvalho CRR, Velasco IT, Forte DN. A decision-aid tool for ICU admission triage is associated with a reduction in potentially inappropriate intensive care unit admissions. J Crit Care 2019;51:77-83.

144. Ratnasingam S, Casan J, Shortt J, Hawkes E, Gilbertson M, McQuilten Z, Grigoriadis G, Htun KT, Htet SM, Campbell P, Chai KL, Quach H, Patil S, Opat S. Cytarabine-based induction immunochemotherapy in the front-line treatment of older patients with mantle cell lymphoma. Sci Rep 2019;9:13544.

145. Reade MC, Marks DC, Bellomo R, Deans R, Faulke DJ, Fraser JF, Gattas DJ, Holley AD, Irving DO, Johnson L, Pearse BL, Royse AG, Wong J, Cryopreserved vs Liquid Platelet (CLIP) Investigators, the Australian and New Zealand College of Anaesthetists Clinical Trials Network, the Australian and New Zealand Intensive Care Society Clinical Trials Group. A randomized, controlled pilot clinical trial of cryopreserved platelets for perioperative surgical bleeding: the CLIP-I trial (Editorial, p. 2759). Transfusion 2019;59:2794-804.

146. Ridley EJ, Parke RL, Davies AR, Bailey M, Hodgson C, Deane AM, McGuinness S, Cooper DJ. What Happens to Nutrition Intake in the Post-Intensive Care Unit Hospitalization Period? An Observational Cohort Study in Critically Ill Adults. JPEN J Parenter Enteral Nutr 2019;43:88-95.

147. Russell H, Churilov L, Toh L, Eastwood GM, Bellomo R. The incidence, predictors and outcomes of QTc prolongation in critically ill patients. J Crit Care 2019;54:244-9.

148. Sanders JM, Opdam HI, Furniss H, Hughes PD, Kanellis J, Jones D. Frequency and outcomes of kidney donation from intensive care patients with acute renal failure requiring renal replacement therapy. Nephrology (Carlton) 2019;24:1296-303.

149. Sartini C, Lomivorotov V, Pieri M, Lopez-Delgado JC, Baiardo Redaelli M, Hajjar L, Pisano A, Likhvantsev V, Fominskiy E, Bradic N, Cabrini L, Novikov M, Avancini D, Riha H, Lembo R, Gazivoda G, Paternoster G, Wang C, Tama S, Alvaro G, Wang CY, Roasio A, Ruggeri L, Yong CY, Pasero D, Severi L, Pasin L, Mancino G, Mura P, Musu M, Spadaro S, Conte M, Lobreglio R, Silvetti S, Votta CD, Belletti A, Di Fraja D, Corradi F, Brusasco C, Saporito E, D’Amico A, Sardo S, Ortalda A, Riefolo C, Fabrizio M, Zangrillo A, Bellomo R, Landoni G. A Systematic Review and International Web-Based Survey of Randomized


Publications (continued) Publications (continued)

Controlled Trials in the Perioperative and Critical Care Setting: Interventions Reducing Mortality. J Cardiothorac Vasc Anesth 2019;33:1430-9.

150. Sartini C, Lomivorotov V, Pisano A, Riha H, Baiardo Redaelli M, Lopez-Delgado JC, Pieri M, Hajjar L, Fominskiy E, Likhvantsev V, Cabrini L, Bradic N, Avancini D, Wang CY, Lembo R, Novikov M, Paternoster G, Gazivoda G, Alvaro G, Roasio A, Wang C, Severi L, Pasin L, Mura P, Musu M, Silvetti S, Votta CD, Belletti A, Corradi F, Brusasco C, Tama S, Ruggeri L, Yong CY, Pasero D, Mancino G, Spadaro S, Conte M, Lobreglio R, Di Fraja D, Saporito E, D’Amico A, Sardo S, Ortalda A, Yavorovskiy A, Riefolo C, Monaco F, Bellomo R, Zangrillo A, Landoni G. A Systematic Review and International Web-Based Survey of Randomized Controlled Trials in the Perioperative and Critical Care Setting: Interventions Increasing Mortality. J Cardiothorac Vasc Anesth 2019;33:2685-94.

151. Schmidt M, Pham T, Arcadipane A, Agerstrand C, Ohshimo S, Pellegrino V, Vuylsteke A, Guervilly C, McGuinness S, Pierard S, Breeding J, Stewart C, Ching SSW, Camuso JM, Stephens RS, King B, Herr D, Schultz MJ, Neuville M, Zogheib E, Mira JP, Roze H, Pierrot M, Tobin A, Hodgson C, Chevret S, Brodie D, Combes A. Mechanical Ventilation Management during Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome. An International Multicenter Prospective Cohort. Am J Respir Crit Care Med 2019;200:1002-12.

152. Secombe P, Brown A, McAnulty G, Pilcher D. Aboriginal and Torres Strait Islander patients requiring critical care: characteristics, resource use, and outcomes. Crit Care Resusc 2019;21:200-11.

153. Secombe PJ, Brown A, Bailey MJ, Pilcher D. Equity for Indigenous Australians in intensive care. Med J Aust 2019;211:297-9 e1.

154. Secombe PJ, Stewart P, Brown A, Bailey MJ, Pilcher D. The impact of an alcohol floor price on critical care admissions in Central Australia. Med J Aust 2019;epub.

155. See EJ, Jayasinghe K, Glassford N, Bailey M, Johnson DW, Polkinghorne KR, Toussaint ND, Bellomo R. Long-term risk of adverse outcomes after acute kidney injury: a systematic review and meta-analysis of cohort studies using consensus definitions of exposure. Kidney Int 2019;95:160-72.

156. Shah A, Nanjayya V, Ihle J. Mitral Annular Plane Systolic Excursion as a predictor of Left Ventricular Ejection Fraction in mechanically ventilated patients. Australas J Ultrasound Med 2019;22:138-42.

157. Shehabi Y, Howe BD, Bellomo R, Arabi YM, Bailey M, Bass FE, Bin Kadiman S, McArthur CJ, Murray L, Reade MC, Seppelt IM, Takala J, Wise MP, Webb SA, ANZICS Clinical Trials Group, the SPICE III Investigators. Early Sedation with Dexmedetomidine in Critically Ill Patients. N Engl J Med 2019;380:2506-17.

158. Sheikh M, Tiruvoipati R, Hurley JC. Non-invasive ventilation of patients with acute asthma. Intern Med J 2019;49:262-4.

159. Sidhu VS, Graves SE, Buchbinder R, Naylor JM, Pratt NL, de Steiger RS, Chong BH, Ackerman IN, Adie S, Harris A, Hansen A, Cripps M, Lorimer M, Webb S, Clavisi O, Griffith EC, Anandan D, O’Donohue G, Kelly TL, Harris IA. CRISTAL: protocol for a cluster randomised, crossover, non-inferiority trial of aspirin compared to low molecular weight heparin for venous thromboembolism prophylaxis in hip or knee arthroplasty, a registry nested study. BMJ Open 2019;9:e031657.

160. Skrifvars MB, Moore E, Martensson J, Bailey M, French C, Presneill J, Nichol A, Little L, Duranteau J, Huet O, Haddad S, Arabi Y, McArthur C, Cooper DJ, Bellomo R, EPO-TBI Investigators, the ANZICS Clinical Trials Group. Erythropoietin in traumatic brain injury associated acute kidney injury: A randomized controlled trial. Acta Anaesthesiol Scand 2019;63:200-7.

161. Smits M, Lin S, Rahme J, Bailey M, Bellomo R, Hardidge A. Blood Pressure and Early Mobilization After Total Hip and Knee Replacements: A Pilot Study on the Impact of Midodrine Hydrochloride. JB JS Open Access 2019;4:e0048.

162. Subbe CP, Bannard-Smith J, Bunch J, Champunot R, DeVita MA, Durham L, Edelson DP, Gonzalez I, Hancock C, Haniffa R, Hartin J, Haskell H, Hogan H, Jones DA, Kalkman CJ, Lighthall

GK, Malycha J, Ni MZ, Phillips AV, Rubulotta F, So RK, Welch J, International Society for Rapid Response Systems. Quality metrics for the evaluation of Rapid Response Systems: Proceedings from the third international consensus conference on Rapid Response Systems. Resuscitation 2019;141:1-12.

163. Tatucu-Babet OA, Ridley EJ. Clinimetrics: Indirect calorimetry. J Physiother 2019;65:240.

164. Tian DH, Smyth C, Keijzers G, Macdonald SP, Peake S, Udy A, Delaney A. Safety of peripheral administration of vasopressor medications: A systematic review. Emerg Med Australas 2019;epub.

165. Tipping CJ, Hodgson CL, Harrold M, Chan T, Holland AE. Frailty in Patients With Trauma Who Are Critically Ill: A Prospective Observational Study to Determine Feasibility, Concordance, and Construct and Predictive Validity of 2 Frailty Measures. Phys Ther 2019;99:1089-97.

166. Toh L, Bitker L, Eastwood GM, Bellomo R. The incidence, characteristics, outcomes and associations of small short-term point-of-care creatinine increases in critically ill patients. J Crit Care 2019;52:227-32.

167. Toolis M, Tiruvoipati R, Botha J, Green C, Subramaniam A. A practice survey of airway management in Australian and New Zealand intensive care units. Crit Care Resusc 2019;21:139-47.

168. Udy AA, Finnis M, Jones D, Delaney A, Macdonald S, Bellomo R, Peake S, ARISE Investigators. Incidence, Patient Characteristics, Mode of Drug Delivery, and Outcomes of Septic Shock Patients Treated With Vasopressors in the ARISE Trial. Shock 2019;52:400-7.

169. Venkatesh B, Finfer S, Cohen J, Rajbhandari D, Arabi Y, Bellomo R, Billot L, Glass P, Joyce C, Li Q, McArthur C, Perner A, Rhodes A, Thompson K, Webb S, Myburgh J. Hydrocortisone Compared with Placebo in Patients with Septic Shock Satisfying the Sepsis-3 Diagnostic Criteria and APROCCHSS Study Inclusion Criteria: A Post Hoc Analysis of the ADRENAL Trial. Anesthesiology 2019;131:1292-300.

170. Warrillow S, Bailey M, Pilcher D, Kazemi A, McArthur C, Young P, Bellomo R. Characteristics and outcomes of patients with acute liver failure admitted to Australian and New Zealand intensive care units. Intern Med J 2019;49:874-85.

171. Warrillow S, Fisher C, Tibballs H, Bailey M, McArthur C, Lawson-Smith P, Prasad B, Anstey M, Venkatesh B, Dashwood G, Walsham J, Holt A, Wiersema U, Gattas D, Zoeller M, Garcia Alvarez M, Bellomo R. Coagulation abnormalities, bleeding, thrombosis, and management of patients with acute liver failure in Australia and New Zealand. J Gastroenterol Hepatol 2019;epub.

172. Warrillow S, Tibballs H, Bailey M, McArthur C, Lawson-Smith P, Prasad B, Anstey M, Venkatesh B, Dashwood G, Walsham J, Holt A, Wiersema U, Gattas D, Zoeller M, Garcia Alvarez M, Bellomo R, Australasian Management of Acute Liver Failure Investigators. Characteristics, management and outcomes of patients with acute liver failure admitted to Australasian intensive care units. Crit Care Resusc 2019;21:188-99.

173. Wigmore G, Anstey J, Deane A, Bellomo R. HAS FLAIR Investigators Reply to Fluid Resuscitation After Cardiac Surgery: The Quest for the Ideal Fluid. J Cardiothorac Vasc Anesth 2019;33:3218-9.

174. Wigmore GJ, Anstey JR, St John A, Greaney J, Morales-Codina M, Presneill JJ, Deane AM, MacIsaac CM, Bailey M, Tatoulis J, Bellomo R. 20% Human Albumin Solution Fluid Bolus Administration Therapy in Patients After Cardiac Surgery (the HAS FLAIR Study). J Cardiothorac Vasc Anesth 2019;33:2920-7.

175. Wong J, Wood EM, Crispin P, Weinkove R, McQuilten ZK, Australasian Leukaemia and Lymphoma Group (ALLG) Supportive Care Group. Managing hypogammaglobulinaemia secondary to haematological malignancies in Australia and New Zealand: a clinician survey. Intern Med J 2019;49:358-63.

176. Young PJ, Bagshaw SM, Bailey M, Bellomo R, Mackle D, Pilcher D, Landoni G, Nichol A, Martin D. O2, do we know what to do? Crit Care Resusc 2019;21:230-32.


2322

Presentations - National / InternationalMonth Conference Location Name Title Role/s

Jan Critical Care Reviews Meeting Dublin,Ireland

Chapman M 1. Session 2 Chair2. SUP-ICU Editorial3. TARGET4. How I Manage Nutrition

Invited Presenter, Panel Member, Session Chair

Jan Critical Care Reviews Meeting Dublin,Ireland

Nichol A 1. PHARLAP Trial Results2. PHARLAP Panel Discussion3. POLAR

Invited Presenter, Panel Member

Feb Australian Society for Antimicrobials 20th ASM

Sydney,Australia

Udy A Antibacterial dosing in the Critically Ill Invited Presenter

Mar 2nd Big Data Machine Learning in Health Care Conference

Tokyo, Japan

Pilcher D Using Registry Data Workshop Organiser and Invited Speaker

Mar ANZICS-CTG 21st Annual Meeting on Clinical Trials in Intensive Care (IC), IC Research Coordinators Interest Group (IRCIG)

Noosa,Australia

Green C ICU nurses’ attitudes towards caring for patients with mental illness

Invited Presenter

Mar ANZICS-CTG 21st Annual Meeting on Clinical Trials in IC, IRCIG

Noosa,Australia

Parke R How to decode research contracts Invited Presenter

Mar ANZICS-CTG 21st Annual Meeting on Clinical Trials in IC, IRCIG

Noosa,Australia

Presneill J Stats in a familiar setting - breaking down an ANZICS-CTG study into meaningful pieces (TARGET)

Invited Presenter

Mar ANZICS-CTG 21st Annual Meeting on Clinical Trials in IC

Noosa,Australia

Bernard S PATCH update Invited Presenter


Noosa,Australia

Burrell A Novice Investigator Session: Rapid Fire Presentation

Invited Presenter


Noosa,Australia

Deane A Day 180 outcome data from TARGET Invited Presenter


Noosa,Australia

Eastwood G TAME update Invited Presenter


Noosa,Australia

French C Session 1 (Chair) Chair, Invited Presenter


Noosa,Australia

Fujii T VITAMINS update Invited Presenter


Noosa,Australia

Hodgson C EXCEL update Invited Presenter


Noosa,Australia

Lambell K Novice Investigator Session: Rapid Fire Presentation

Invited Presenter


Noosa,Australia

MacDonald S, Keijzers G

ARISE Fluids Observational Invited Presenters


Noosa,Australia

May L BLENDER update Invited Presenter


Noosa,Australia

Peake S 1. Session 2 (Chair)2. TARGET results

Convenor, Chair, Presenter


Noosa,Australia

Reade M CLIP II update Invited Presenter, Panel Member


Noosa,Australia

Ridley E INTENT update Invited Presenter


Noosa,Australia

Tatucu-Babet O

Novice Investigator Session: Rapid Fire Presentation

Invited Presenter


Noosa,Australia

Udy A 1. PROMOTE-SAH results2. BONANZA update

Chair, Presenter


Noosa,Australia

Webb S Reform in the Australian Clinical Trial Sector Invited Presenter


Noosa,Australia

Young P ICU-ROX results Invited Presenter

Mar ANZICS-CTG 21st Annual Meeting on Clinical Trials in IC, Pre-clinical Research Meeting

Noosa,Australia

Bellomo R Effects of fluid bolus therapy on renal perfusion, oxygenation, and function in experimental septic kidney injury

Invited Presenter

Mar ANZICS-CTG 21st Annual Meeting on Clinical Trials in IC, Pre-clinical Research Meeting

Noosa,Australia

Hodgson C PHARLAP sub-study Invited Presenter

177. Young PJ, Bailey MJ, Bass F, Beasley RW, Freebairn RC, Hammond NE, van Haren FMP, Harward ML, Henderson SJ, Mackle DM, McArthur CJ, McGuinness SP, Myburgh JA, Saxena MK, Turner AM, Webb SAR, Bellomo R, REACTOR Investigators, ANZICS Clinical Trials Group. Randomised evaluation of active control of temperature versus ordinary temperature management (REACTOR) trial. Intensive Care Med 2019;45:1382-91.

178. Young PJ, Bellomo R. The Risk of Hyperoxemia in ICU Patients. Much Ado About O2. Am J Respir Crit Care Med 2019;200:1333-5.

179. Zeiler FA, McFadyen C, Newcombe VFJ, Synnot A, Donoghue EL, Ripatti S, Steyerberg EW, Gruen RL, McAllister TW, Rosand J, Palotie A, Maas AIR, Menon DK. Genetic Influences on Patient-Oriented Outcomes in Traumatic Brain Injury: A Living Systematic Review of Non-Apolipoprotein E Single-Nucleotide Polymorphisms. J Neurotrauma 2019;epub.

180. Zweng I, Galvin S, Robbins R, Bellomo R, Hart GK, Seevanayagam S, Matalanis G. Initial Experience of the Use of 3-Factor Prothrombin Complex Concentrate and Thromboembolic Complications After Cardiac Surgery. Heart Lung Circ 2019;28:1706-13.

181. Barlow CJ, Pilcher D. Chapter 3: Severity scoring and outcome prediction. In: Bersten AD, Handy JM, eds. Oh’s Intensive Care Manual. 8th ed: Elsevier (ISBN 9780702072215; eBook 978-0-7020-7606-0); 2019:19-33.

182. Cooper DJ, Newcombe V. Chapter 5: Severe traumatic brain injury. In: Gough C, Barnett J, Cook T, Nolan J, eds. Challenging Concepts in Critical Care: Oxford University Press (ISBN: 9780198814924); 2019.

183. Cosgrave DW, Higgins AM, Cooper DJ, Nichol AD. Chapter 19: Hyperlactataemia in critical illness. In: Bersten AD, Handy JM, eds. Oh’s Intensive Care Manual. 8th ed: Elsevier (ISBN 9780702072215; eBook 978-0-7020-7606-0); 2019:171-80.

184. Delaney A, Finfer S. Chapter 95: Fluid and electrolyte therapy. In: Bersten AD, Handy JM, eds. Oh’s Intensive Care Manual. 8th ed: Elsevier (ISBN : 9780702072215; eBook: 978-0-7020-7606-0); 2019:1118-28.

185. Dutch M, Pilcher D. Section 21: Challenging Situations - Organ and Tissue Donation. In: Little M, Mitra B, Deasy C, eds. Textbook of Adult Emergency Medicine. 5th ed: Elsevier (eBook ISBN 9780702076251; Paperback ISBN 9780702076244); 2019.

186. Finfer S, Delaney A. Chapter 10: Trials. In: Bersten AD, Handy JM, eds. Oh’s Intensive Care Manual. 8th ed: Elsevier (ISBN: 9780702072215; eBook 978-0-7020-7606-0); 2019:82-92.

187. Isbister JP, French C. Chapter 97: Blood transfusion and patient blood management. In: Bersten AD, Handy JM, eds. Oh’s Intensive Care Manual. 8th ed: Elsevier (ISBN: 9780702072215; eBook 978-0-7020-7606-0); 2019:1145-58.

188. Maiden MJ, Peake SL. Chapter 15: Overview of shock. In: Bersten AD, Handy JM, eds. Oh’s Intensive Care Manual. 8th ed: Elsevier (ISBN: 9780702072215; eBook 978-0-7020-7606-0); 2019:128-33.

189. Nichol A, Geoghegan P, Duff S, Pettila V, Cooper DJ. Chapter 9: What is the Optimal Approach to Weaning and Liberation from Mechanical Ventilation? In: Deutschman CS, Neligan PJ, eds. Evidence-based practice of critical care. 3rd ed. Philadelphia, PA: Elsevier; 2019.

190. Pellegrino V, Richardson A. Chapter 41: Extracorporeal membrane oxygenation. In: Bersten AD, Handy JM, eds. Oh’s Intensive Care Manual. 8th ed: Elsevier (ISBN: 9780702072215; eBook 978-0-7020-7606-0); 2019:533-50.

Journal Publications (continued) Books / Book Chapters


2524

Presentations - National / International (continued) Presentations - National / International (continued)

Month Conference Location Name Title Role/s

Mar SMACC Sydney,Australia

Davies A 1. The 3 R’s: Rest2. People and the Planet: Practitioners as People

Panel Discussion



Hodgson C 1. Science and Innovation: Sowing the Seeds of Creativity Panel Discussion

2. Patient-Centred Research from Theory to Reality3. Science and Innovation: From Think Tank to Do

Tank - Making Great Ideas Happen Panel Discussion4. Surviving the Aftermath of ECMO5. Bedside Critical Care Panel Discussion



Myburgh J The Great(est) Fluid Debate Invited Presenter

Apr National DonateLife Forum Sydney,Australia

Pilcher D Twelve Years of Increasing Admissions from the Emergency Department to ICU for Potential Organ Donation (2007-2018)

Invited Presenter

May Annual Congress of Anaesthesiology and ICM

Dublin,Ireland

Nichol A Monitoring in ICU: worth the effort? To cool the injured brain - how low, how long, if at all?

Invited Presenter

May Collaborative Clinical Trials in Intensive Care Medicine

Prato, Italy

Bailey M Translation of Cardiac Arrest Research into Practice Invited Presenter


Prato, Italy

Bellomo R 1. Angiotensin II in Septic Shock and the Three Musketeers

2. Why We Should Be LUCID About Diabetic Patients 3. Dexmedetomidine for ICU - SPICE Trial Results

Invited Presenter


Prato, Italy

Cooper DJ 1. Successful Publishing: How to get a Hat Trick (Chair)2. POLAR Results and Beyond (Presenter)3. Blood Sessions (Chair)4. Successful Publishing: Tips from the Editor (Chair)5. Hot Topics in ICU Research Sessions (Co-Chair)

Convenor, Presenter,Session Chair


Prato, Italy

Eastwood G Saving the Brain in Cardiac Arrest: TAME and Beyond Invited Presenter


Prato, Italy

French C 1. Beyond TRANSFUSE (Panel Member)2. EPO-TRAUMA (Presenter)



Prato, Italy

Glassford N IV Fluid Therapy and Patient-Centred Outcomes Invited Presenter


Prato, Italy

Higgins L 1. Beyond TRANSFUSE (Panel Member)2. Tell Me Why? Sessions Day 2 (Chair)3. Cardiac Arrest Sessions (Co-Chair)4. How to Keep Data Integrity (Presenter)

Invited Presenter, Panel Member,Session Chair


Prato, Italy

Hodgson C 1. Building an International Database as a Platform for Clinical Trials

2. Tell Me Why? Sessions Day 1 (Chair)3. International Collaboration in Rehabilitation and

Recovery4. Tell Me Why? Sessions Day 3 (Chair)

Organising Committee, Presenter, Session Chair


Prato, Italy

Jones D Rehabilitation and Recovery Sessions (Chair) Session Chair


Prato, Italy

McArthur C Clinical Trial Participation: Sign Me Up! Invited Presenter


Prato, Italy

McGuinness S Cardiac Surgery Gone Wrong Invited Presenter


Prato, Italy

McQuilten Z 1. Beyond TRANSFUSE (Presenter)2. Beyond TRANSFUSE (Panel Member)



Prato, Italy

Nichol A 1. Adaptive Trials: Embedding - a Public Perspective2. RESURRECT

Organising Committee, Presenter


Prato, Italy

Pellegrino V ECMO Sessions (Chair) Organising Committee, Session Chair


Prato, Italy

Presneill J Platforms, Adaptive and Bayesian - What Every Clinician Needs to Know

Invited Presenter


Prato, Italy

Ridley E 1. TARGET (Chair)2. Optimal Nutrition When You Need It Most –

Recovery from Acute Illness

Invited Presenter, Session Chair


Prato, Italy

Rowan K Expanding Collaborations: Australia/New Zealand and UK

Invited Presenter

Photography: Peter Harrigan, et al



Prato, Italy

Schmidt M EOLIA and Beyond Invited Presenter


Prato, Italy

Skrifvars M Is Mannatol the Starch of TBI? Invited Presenter


Prato, Italy

Udy A Sepsis Sessions (Chair) Organising Committee,Session Chair


Prato, Italy

Webb S The Pandemic is Coming Invited Presenter

May National Clinical Programme for Critical Care Conference

Dublin,Ireland

Nichol A The Importance of Research in Critical Care Invited Presenter

May National Taiwanese University Hospital

Taipei, Taiwan

Pilcher D 1. Lung Transplantation – post-operative care2. Using a registry for research and trials

Invited Presenter

May Taiwanese ECMO Special Interest Group

Taipei, Taiwan

Pilcher D Scoring Systems for ECMO Invited Presenter

May Taiwanese Society of Organ Donation and Transplantation

Taipei, Taiwan

Pilcher D Identification of Organ Donors Invited Presenter

May Visiting Professor Koohsiung,Taiwan

Pilcher D ANZICS Registry and Big Data in Intensive Care Invited Presenter

May Visiting Professor Taichung,Taiwan

Pilcher D The impact of the ANZICS Registry Invited Presenter

Jun ANZICS Critical Care Datathon Brisbane, Australia

Pilcher D Organising Committee Chair

Jun Connecting the Dots Stroke Treatment Symposium

MelbourneAustralia

Gantner D Critical Stroke Care - The Role of ICU Invited Presenter

Jun CICM ASM Trauma - A Crash Course

Cairns, Australia

Udy A Emerging Neuromonitoring Techniques in Traumatic Brain Injury

Invited Presenter

Photography: Peter Harrigan et al

2726

Presentations - National / International (continued) Presentations - National / International (continued)


Oct World Congress of Intensive Care

Melbourne,Australia

French C EPO in trauma. Chimera or Panacea? Invited Presenter


Melbourne,Australia

Fujii T The VITAMINS trial - first presentation of results Invited Presenter


Melbourne,Australia

Hodgson C 1. Mobilisation during and after ECMO (with Shannah Anderson)

2. Disability in survivors of critical illness (incl ICU Mobility Scale)

Invited Presenter


Melbourne,Australia

Levkovich B Medications contribution to, and use during clinical dete-rioration

Invited Presenter


Melbourne,Australia

McGuinness S Recent CTG trial results: RELIEF Invited Presenter


Melbourne,Australia

McQuilten Z Transfusion practice in ICU: Getting the cocktail right Invited Presenter


Melbourne,Australia

Nichol A Recruitment as a treatment for hypoxia? Invited Presenter


Melbourne,Australia

Orford N 1. From critical to broken - the impact of critical illness bone loss

2. Back on deck tomorrow: Strengthening ICU teams through improving EoL care

Invited Presenter


Melbourne,Australia

Parke R Adjunctive therapies in ARDS - what should we be doing? Invited Presenter


Melbourne,Australia

Peake S Recent CTG trial results: TARGET Invited Presenter


Melbourne,Australia

Pilcher D 1. When Risk Management has Unintended Consequences 2. International Benchmarking of Intensive Care Outcomes 3. Extending Opportunities for Donation after Circulatory

Death in Australia4. Long-term Survival 10 Years after Admission to ICU 5. Readmission to ICU during Future Hospitalisations



Melbourne,Australia

Poole A Conservative vs. liberal: How politics can inform glucose management

Invited Presenter


Melbourne,Australia

Reade M 1. Effectiveness of pharmacological interventions in reduc-ing delirium in critical ill adults

2. On target: What can civilian ICU teams learn from the military? Panel Discussion



Melbourne,Australia

Ridley E 1. Can social media bridge the gap between research and practice?

2. Nutrition - What can we do about it?

Panel Member


Melbourne,Australia

Shehabi Y Recent CTG trial results: SPICE III Invited Presenter


Melbourne,Australia

Tiruvoipati R Hypercapnia in sepsis - time to target? Invited Presenter


Melbourne,Australia

Udy A Outcomes of SAH requiring ICU admission Invited Presenter


Melbourne,Australia

Young P First release of ICU-ROX Invited Presenter


Jul ICU Physiotherapy and Multidisciplinary Symposium - State of the Art in ICU

Melbourne, Australia

Hodgson C Life after ICU - the patient’s story Co-Convenor, Presenter



Lang J Guidelines for early mobilisation in ICU Invited Presenter



Paton M Early mobilisation - what about dosage? Invited Presenter

Jul Singapore Critical Care Datathon

Singapore,Singapore

Pilcher D Critical Care Data Analytics Course Session Mentor

Sep Annual Scientific Meeting on Intensive Care (ASMIC)

Kuala Lumpur, Malaysia

Cooper DJ 1. Randomised trials guide: hypothermia in severe TBI2. Implications of decompressive craniectomy for TBI3. Meet the Expert: How I manage severe head injury

patients

Invited Presenter

Sep Health Big Data and Enterprise Architecture Convergence Workshop

Thimphu,Bhutan

Pilcher D Creating a scientific publication from Intensive Care Registry data

Invited Presenter and Workshop

Oct 7th National Brain Injury Conference

Melbourne,Australia

Nichol A 1. Neurotrauma Research: Working where head injury ends and brain injury begins

2. The use of erythropoietin (EPO) after severe multi-trauma

Panel member,Invited presenter

Oct 7th National Brain Injury Conference

Melbourne,Australia

Udy A Brain tissue oxygen monitoring in Traumatic Brain Injury: An emerging neuromonitoring technique

Invited Presenter

Oct AAHMS 4th Annual Life as a Clinician Scientist Symposium

Melbourne,Australia

Cooper DJ The how, the what and the why of research – Science and patient care synergise in Intensive Care

Invited Presenter

Oct Paris Rescue Team Course Paris,France

Ihle J 1. Percutaneous ECMO Cannulation Technique2. Veno-Venous ECMO

Invited Presenter


Melbourne,Australia

Bellomo R 1. The meaning and treatment of constipation2. The role of angiotension II in critical care3. Designing high quality interventional trials

Invited Presenter


Melbourne,Australia

Bucknall T 1. What is the state of the science for rapid response systems?

2. Disinvesting when evidence changes

Invited Presenter


Melbourne,Australia

Chapman M 1. First release of CRASH-3 Editorial2. The gastrointestinal tract is maladaptive to surviving

critical illness in the 21st century3. TARGET d-180 outcomes: First presentation of

functional outcomes

Invited Presenter


Melbourne,Australia

Cooper DJ 1. Traumatic injury with pressure – should we hypo-therm or barbiturise?

2. Recent CTG trial results: POLAR

Invited Presenter


Melbourne,Australia

Davies A 1. Physician: Heal thyself2. Role of podcasts in intensive care3. Can social media bridge the gap between research

and practice? Panel Discussion



Melbourne,Australia

Eastwood G Saving the brain by breathing less Invited Presenter

Australian and New ZealandIntensive Care Research Centre553 St Kilda Road, Melbourne, Victoria, Australia 3004

anzicrc.monash.org

australian and new zealand intensive care research centre ... · a/prof ian seppelt dr guillaume...

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