135

Index

agranulocytosis, in beagle 55AIHA, see anemia, auto-immune

hemolyticanemia

auto-immune, in dog 54azobenzene-induced, in mouse 7in cat 43hemolytic 54, 79Heinz body 68in marmoset 69in mouse 6

androgen inhibitor, emperipolesis in rat 31

anticoagulants 110aplasia

in dog 60, 61in mouse, following treatment with

busulphan 9artefacts

anticoagulant 110in cat 111miscellaneous 114smear preparation 113stain precipitate 113storage 111, 112time-related 109

arterio-venous shunt 69auto-immume hemolytic anemia (AIHA)

54automated analysers

Advia 120 and Advia 2120 122Celldyn 3500 123Hemavet 950 124Sysmex XT200iv 123Vetscan HM5 124

azobenzene (AZB)-induced hemolytic anemia, in mouse 7

baboon (Papio cynocephalus)bone marrow, normal development

84, 85Hepatocystis simiae 85normal 85peripheral blood 84plasma cell in 85red cell agglutination 85

bacteremia 59, 69basophilic stippling

in dog 62in marmoset 69

Atlas of Comparative Diagnostic and Experimental Hematology, Second Edition. Clifford Smith, Alfred Jarecki.© 2011 Blackwell Publishing Ltd. Published 2011 by Blackwell Publishing Ltd.

bleeding sites, common 105bone marrow sampling

Cytospin preparations 118fl ow cytometric analysis

preparation 117, 124introduction 115myeloid and erythroid left shift indices

(M-LSI, E-LSI) 119recommended methods 116

aspiration sites 115,116intramedullary needle (e.g.

Rosenthal, Gimson, etc.) 115short coagulation time of bone

marrow 115smear

evaluation 119M : E ratio 119myelogram 119

interpretation 119, 120preparation and staining 118

total cell count 116burr cells 61, 109, 110busulphan 9

carp, peripheral blood 101, 102cat

anemia 43bleeding site 106Döhle bodies 44eosinophilia 42erythroleukemia 44Heinz bodies 44peripheral blood

feline leukemia virus 44normal blood picture 41rouleaux 44

platelet, clumping 41cattle

bleeding sites 106bone marrow sampling 115

crenation 90, 96, 97, 109, 110cynomolgus (Macaca fascicularis)

bleeding sites 106bone marrow

dyserythropoesis 81, 82normal development 81, 84sampling 116

Dirofi laria immitis 82hemolytic anemia 79herpesvirus simiae B virus 80

microfi laria 83normal 82peripheral blood 78Plasmodium cynomolgi 80Plasmodium falciparum 80reference ranges 72, 73, 74, 75, 76, 77,

78reticulum cell 81

cytochemistry 29, 30, 34, 69, 71

Dirofi laria immitis 82distemper, canine 55dog

AIHA 54anemia

aplastic 51, 60, 61auto-immune hemolytic 54

bacteremia 55bleeding site 105, 106blood picture 49bone marrow 50

AIHA 54emperipolesis 54erythroid hypoplasia 52, 53erythrophagocytosis 54lymphoma 64myeloma 61sampling 116

distemper 55erythrocytes, in AIHA 54erythroid hyperplasia 63erythroid hypoplasia 52, 53Heinz body 56hemoglobin, normal age range 46Howell-Jolly bodies, viral inclusion

bodies resembling 55lymphocytes, normal age range 49lymphoma 56, 57, 58MCV, normal age range 46polychromasia, in AIHA 50, 51,

52pseudo Pelger-Huet 61red blood cells, normal age range

46toxic monocytes 59, 60uremia 61white blood cells, normal age range

48Döhle bodies 44,56dyserythropoesis 81, 82

136 Index

eastern quollbone marrow 97peripheral blood 97

EDTA 110, 111, 112emperipolesis 31, 54erythroid hyperplasia

in dog bone marrow 52, 53, 71in pig 91

erythroleukemia 44erythrophagocytosis

in dog 54in wasting marmoset syndrome 70

fl ow cytometrybone marrow analysis 124, 125, 126,

127, 128hematology analysers 122, 123,

124lymphocyte phenotyping 130micronucleus 130neutrophil function 128phospholipidosis 130, 132platelet function assays 129reticulocyte analysis 128

feline leukemia virus 44ferret

blood picture 96bone marrow 96peripheral blood 96

Foa-Kurloff bodies 17

Gaucher cells, mouse bone marrow 12giant platelets 50, 56goat

blood picture 94bone marrow 95peripheral blood 94

aggregation of platelets 94normal leukocytes 94, 95

guinea pigbleeding site 106blood picture 17bone marrow 18Foa-Kurloff bodies 17peripheral blood 17

histiocytes 17normal 17

hamsterbleeding site 106bone marrow 16

sampling 116peripheral blood

lymphocyte 15, 16neutrophil 15, 16polychromasia 15, 16

Heinz bodiesin beagle 56in cat 44in marmoset 66, 68, 70

in mouse 7in pig 90

hemoglobin crystals 2, 19, 90, 46, 66, 72Hepatocystis simiae 85, 86, 87herpesvirus simiae B virus 80heterophils 98histiocytes 14, 34histiocytic lymphosarcoma (HLS) 26,

30bone marrow 30in rat 26, 30

horseagranular neutrophil 92bleeding site 106blood picture 92, 93bone marrow 93, 94

osteoclasts 94eosinophils 92hot blooded/cold blooded 91lymphocytes 92lymphosarcoma 92neutrophils 92peripheral blood 92, 93

lymphoma 92normal leucocytes 91rouleaux 92

plasma cell 92Howell-Jolly bodies

in dog 45in marmoset 68, 69in mouse 7in rat 24, 25, 27viral inclusion bodies resembling, in

canine distemper 55

immunohematology, lymphocyte subset analysis 130

labrador, lymphoma 58leukemia

lymphoblastic, in rat 27, 28, 29, 30mast cell leukemia, in mouse 13

little penguin, peripheral bloodnucleated erythrocytes 97, 98heterophils 97, 98

lymphomain dog 56, 57, 58, 62, 63, 64in horse, circulating cells 93in mouse, peripheral blood 8, 11, 12,

112in rat 27, 28, 29, 33

lymphosarcoma 7clover leaf, in horse 93in mouse, platelet satellitism and

polychromasia 7

marmosetbacteremia, due to infected arterio-

venous shunt 69basophilia, punctuate 70

blood picture 67bone marrow 67

macrophages showing erythrophagocytosis 70

normal appearance 70eosinophils, peripheral blood 67erythroid hyperplasia 71erythrophagocytosis 70Heinz bodies, hemolytic anemia 68Howell-Jolly bodies 68hypochromia, in wasting syndrome 70lymphocytes

lymphoma 69peripheral blood 67smear cell appearance of 68

macrophages, erythrophagocytosis 70monocytes, peripheral blood 67normoblast, in wasting syndrome 70peripheral blood

bacteremia due to infected shunt 69leukocytes 67reference ranges 66reticulocytes, in wasting syndrome

70smear cells 68stomatocytes 67, 70

mast cell leukemias, in mouse 13megakaryocytes

in monkey 81in rat 31, 34

microfi laria 35, 83mouse

anemia 6azobenzene-induced, hemolytic 7bleeding site 105, 106bone marrow

Gaucher cells 12myeloid hyperplasia 9normal smear 5, 6sampling 116

eosinophil, normal 5hemoglobin, normal range with age 2Heinz bodies 7Howell-Jolly bodies 7lymphocytes, normal age range 5lymphoma 7, 8, 11, 12lymphosarcoma 7mast cell leukemia 13MCV, normal age range 2myeloid hyperplasia 9neutrophils 5

normal 5normal age range 4

peripheral bloodazobenzene-induced hemolytic

anemia 7histiocytes – accidentally lung dosed

animal 9, 14lymphoma 7, 8, 11mast cell leukemia 13

Index 137

neutrophilia 9platelet satellitism 7, 9platelets, normal range with age 3polychromasia 5, 6, 7, 9, 12polychromatic aggregates 6, 7, 12red blood cells, normal range with

age 2renal failure 9thrombocythemia 10

myeloid hyperplasia, in mouse 9myeloma

bone marrow 61in dog 61

opossum, peripheral bloodcrenated red cells 96, 97myelocyte 96, 97

osteoclasts 94

parasitic infestationsin baboon, Hepatocystis simiae 85in cynomolgus

Dirofi liaria immitis 82Plasmodium cynomolgi 80Plasmodium falciparum 80

in rat 35in rhesus monkey, Hepatocystis simiae

86, 87peritoneal wash, rat 35, 36pig

bleeding site 106blood picture 90bone marrow 91

sampling 116Heinz bodies 90peripheral blood, normal 90

Plasmodium cynomolgi 80Plasmodium falciparum 80platelet satellitism 113

in mouse 7in rat 28

polychromasiain dog 50, 51, 52, 54in hamster 16in mouse 5, 6, 7, 12in rat 26, 27, 30

polychromatic aggregates, in mouse 6, 7, 12

poodle, lymphoma 56

rabbitbleeding site 106blood picture 38bone marrow 38

sampling 116thorn apple red cells 38

rainbow trout, peripheral blood, normal leukocytes 102

ratandrogen synthesis inhibitor, bone

marrow 31artefactual changes 107, 108, 109bacteria 35bleeding site 105, 106bone marrow

artefactual changes 117emperipolesis and androgen

synthesis inhibitor 31Howell-Jolly bodies 25immunohematology 130normal 23reticulum cell 25sampling 116

dysplastic red cells 35emperipolesis 31eosinophil, normal 22, 23hemoglobin, normal range with age

19crystallisation in blood fi lm 32, 33

histiocytic lymphosarcomabone marrow 30cardiac blood 26peripheral blood 26

Howell-Jolly body, peripheral blood 24

leukocytes, normal range with age 22lymphoblastic leukemia 27, 28, 29,

30lymphocytes

artefactual changes 110normal appearance, peripheral

blood 22, 23, 24normal range with age 22subset analysis 130

lymphoma 27, 28, 29, 30, 33MCV, normal age range 20megakaryocytes 31, 34microfi laria 35monocyte, normal 22, 23

neutrophilsnormal age range 22normal appearance, peripheral

blood 22, 23, 24normal 22, 23normal, Wright staining 22, 23peripheral blood 22, 23peritoneal wash 36plasma cells 34platelets

normal age range 21satellitism 28

polychromasia 24, 26, 27, 30pseudo-basophils 112red blood cells, normal age range 19reticulocytes 35target cell 23, 24

reticulocytes, in dog 47reticulum cell 25, 81rhesus monkey

bone marrow, normal development 86

parasitemia 86, 87peripheral blood, normal 86

rouleaux 44, 92

schistocytes 79sheep, peripheral blood, normal 95southern elephant seal 98, 99southern hairy-nosed wombat, periph-

eral blood, normal 100spaniel, toxic monocytes 59, 60spherocytes 9, 79

tammar wallaby, peripheral blood, normal 102, 103

target cells 23, 24Tasmanian devil 100, 101thrombocythemia, in mouse, peripheral

blood 10tortoise 101

uremia 61

vitamin E 66

wasting marmoset syndrome, see marmoset, wasting syndrome 66, 70