ASKORBIPOL®Vitamin C 100 mg

KomposisiTiap tablet mengandungVitamin C 100 mgIndikasi

Mengobati dan mencegah skorbut, sariawan dan sebagai suplemen.Kontraindikasi

Hipersensitif terhadap sodium, tartrat, asam askorbat.Mekanisme Kerja

Skorbut disebabkan karena defisiensi vitamin C. Asam askorbat penting dalam sintesis jaringan konektif, yang menjadi penyebab terjadinya pembusukan jaringan elastin sehingga terjadinya skorbut.Farmakokinetika

Asam askorbat diserap dari saluran pencernaan dan secara luas didistribusikan pada jaringan. Konsentrasi Plasma asam askorbat meningkat seiring dengan dosis tinggi dicapai, sekitar 90-150 mg dalam sehari. Konsentrasi tertinggi terdapat pada leukosit dan platelets dibanding eritrosit dan plasma. Asam askorbat dieliminasi melalui urin.Efek Samping

Dosis yang besar menyebabkan diare dan masalah pencernaan lainya, mual muntah, rasa panas dalam perut, keram, kelelahan, sakit kepala, dan insomnia.Perhatian

- Ibu hamil dan menyusui- Pasien hemolisis- Pasien penyakit ginjal

Aturan Pakai1-3 tablet dalam sehari

Simpan pada tempat sejuk dan kering

IngredientsEach tablet containsVitamin C 100 mgIndication

Ascorbic acid is used to prevent and to treat scurvy, and as supplement.Contra Indications

Hypersensitive to sodium, tartrat, ascorbic acid.Working Mechanism

Ascorbic acid deficiency results in scurvy. The importance of the role of ascorbate in connective tissue synthesis is evident in deterioration of elastic tissue that occurs with scurvy, the clinical ascorbic acid deficiency disease.Pharmacokinetics Ascorbic acid is readily absorbed from the gastrointestinal tract and is widely distributed in the body tissues. Plasma concentrations of ascorbic acid rise as the dose ingested is increased until a plateau is reached with doses of about 90 to 150 mg daily. Body stores of ascorbic acid in health are about 1.5 g although more may be stored at intakes above 200 mg daily. The concentration is higher in leucocytes and platelets than in erythrocytes and plasma. Ascorbic acid in excess of the body’s needs is also rapidly eliminated unchanged in the urine.Side Effects

In large dosage, adverse effect diarrhea and GI tract disturbance, nausea, vomiting, heartburn, abdominal cramps, fatigue, flushing, headache, and insomnia.Attention

- Pregnancy and lactation- Hemolysis patient- Kidney disease patient

Dosage1-3 tablet(s) each day.

Store in a cool and dry place

PT. GASPOLMakassar-Indonesia

No.Reg : DBL 160000100303 A1