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Noninvasive Liver Fibrosis Evaluation by Acuson S2000 and FibroScan on 554 cases:
Comparison ARFI to Transient Elastography

LIEM THANH LE, LINH HONG BUI, NHAT THONG LE, HAI THANH PHAN
DEPARTMENT OF ULTRASONOGRAPHYMEDIC MEDICAL CENTER, HCMC, VIETNAM

INTRODUCTION

In Viet Nam, the incidence of hepatitis B and C is more than 20% of the population (about 18 million people).

Liver biopsy is still gold standard for assessment of liver fibrosis staging. However, this is an invasive procedure.

Since 2003, transient elastography [TE] - FibroScan) is an alternative procedure for chronic liver diseases. However, TE, a sonoelastography technique, using ultrasound A mode.

Recently, ARFI technique emerged as a new elastographic quantification of non-invasive of liver fibrosis, and integrated in conventional ultrasound. ARFI not yet widely used in clinical practice.

We have conducted a study comparing the correlation between ARFI and TE technique in order to find out whether ARFI could replace TE or not.

MATERIALS AND METHODS

It is a descriptive cross sectional study

554 patients (353 men and 201 women, age from 17 to 85 yo (mean = 44+/-13.28), BMI=14.8 to 32.4 (mean= 22.19+/-2.85), 366 patients with chronic HBV or HCV

FibroScan failed in measurement (one patient was overweight (BMI=29.13, VS=3.47m/s) and one patient was cirrhosis with ascites, (BMI=21.11, VS=1.83m/s))

2 sonologists measured ARFI (3 times) and TE techniques (6 or 10 times), in the same site and the same day.

ARFI values are compared to TE values by MedCalc statistical software, and serologic markers tests are the standard reference.

G:\ARFI&FS-Acuson 2000-Siemens\HNH CHUN\hinh\FS.bmpG:\ARFI&FS-Acuson 2000-Siemens\HNH CHUN\hinh\untitled.bmpG:\ARFI&FS-Acuson 2000-Siemens\HNH CHUN\H1.jpgRESULTS

Fig 4: Correlation between ARFI and TE, r=0.8319, p