Unique Opportunity for AOCC

--- Biological Big Data & Global Collaboration

Xu XunExecutive Director of BGI Research

‘Omics’ data Environments Modeling

Single Gene

Multiple Gene

Single Gene

Multiple Gene

Phenotypes

Different combinations

What happen 5 years from now?

Moore’s law in Biology: Big Data Challenge and opportunity

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Road map from Genome to Field

Agriculture

kung pao chickenPeking Duck

Mapo toufu

Cabbagecucumber

oyster

“taste good, sequence it!”

Any species at the dinner menu should be sequenced!

Industry

“Useful, sequence it!”

Silk and silkworm Oil and castor bean

Cloth and cotton

Any species at the industrial use should be sequenced!

Fun

“look cute, sequence it!”

Any endanger species; any Evolutionary/Scientifically important species should be sequenced!

14 crops

70 vegetables

39 animals

Agricultural Genomes

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From genome paper to seeds and yield --- demo case in foxtail millet

Improve the phenotype by Whole Genome Selection

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Select the right parents for heterosis

Yield: 9-12 t/ha; Traditional cultivars: 3-4 t/ha. Only need

1/2 of the water of Corn. Its drought tolerance can even adapted to desert region

Non-shattering cultivar

Hybrid F1

Backcrossing

Non-shattering super rice

Targeted Genome Improvement by Genome-Wide-Selection for Chinese Super Rice

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Digital Breeding in Supercomputer

Breeding purpose

Resources

Markers and the relationship between markers and traits

Breeding process

Markers based selection

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Global Collaboration--- BGI’s genes since its beginning

Why BGI was founded? Only for participate 1% HGP project

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Global Collaboration--- BGI’s genes since its beginning

10% of Hapmap

Leading role in the 1000 project

AOCC today, and 1 year later

List of plans Publications Seeds

Global Collaboration is the Bridge