antidepresivos triciclicos.ppt

7/25/2019 ANTIDEPRESIVOS TRICICLICOS.ppt

1/53

RESIDENTE: ONTIVEROS, CARMENRESIDENTE: ONTIVEROS, CARMEN R1 PSIQUIATRIAR1 PSIQUIATRIA TUTOR: DR. PIERINI ITALOTUTOR: DR. PIERINI ITALO

SAN CRISTBAL, JUNIO 2.014 SAN CRISTBAL, JUNIO 2.014

RPUBLICA BOLIVARIANA DE VENEZUELARPUBLICA BOLIVARIANA DE VENEZUELAUNIVERSIDAD DE LOS ANDESUNIVERSIDAD DE LOS ANDES

EXTENSIN TCIRAEXTENSIN TCIRACSC ! PSIQUIATR"ACSC ! PSIQUIATR"A


2/53

ANTIDEPRESIVOS TRIC"CLICOS

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 676


3/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 676

ROLAND 8UN 94 M$#+ 1;12 < 10 O+%'=(#200>? @$) $ S@*)) )+*$%#*)% @'

&*)+'(#(& %$% %( / *-*#$-*( $&

$%*&(#())$% #'(#%*(). ( @$) ='# *B*( $& &*(& * S+(#*/(


4/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 676


5/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 676
http://quieromusica.net/http://quieromusica.net/http://quieromusica.net/http://quieromusica.net/


6/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 676

CIRCULACIN SISTMICA 9>0 !50?FUNIN A LAS PROTEINAS 96> !;0?FCONCENTRACIN MXIMA AMINAS TERCIARIAS 91 !3? '#$)

AMINAS

SECUNDARIAS 94 ! 7? '#$)MESETA DE CONCENTRACIN

PLASMTICA 9> ! 6? &$)LIPOSOLUBILIDAD ALTA

VOLUMEN DE DISTRIBUCIN AMINAS TERCIARIAS 910 !30?G8/

AMINAS

SECUNDARIAS 920 ! 50? G8/

VOLUMEN DE CONCENTRACIN

PLAMTICAEHECTO

TERAPUTICO

9>0 ! 300?

/G-

NIVELES TXICOS 90,> < 1?/G-SEMIVIDA 910 !60? '#$)


7/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 676


8/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 677


9/53

BASES BIOLICAS DE LA DEPRESIN

PSICOHARMACOLO"A ESENCIAL. S%(( M. S%$. 2 (&. C$ >. P/. 15;


10/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 677

X


11/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 677


12/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 677


13/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 677


14/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 677


15/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 6;>


16/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 6;>

"
http://quieromusica.net/


17/53


-ESQUIZOHRENIA-

BIPOLARES IPOMANIACOS-IDEAS DE SUICIDIO-ALTERACIONES CARDIOVASCULARES-ENHERMEDAD RENAL-ALTERACIONES EPTICAS-IPERTROHIA PROSTTICA-LAUCOMA-ESTREIMIENTO CRNICO-HEOCROMOCITOMA-EPILEPSIA

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 6;>

"


18/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 677

"


19/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 6;5

"


20/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 6;5

"


21/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 6;5

S OS C"C COS


22/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 6;5


23/53



24/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 67;



25/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 67;



26/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 67;



27/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 67;


28/53

IMAO


29/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;6

IMAO


30/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;6

IMAO


31/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 677

IMAO


32/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

ABSORCION ORAL RPIDA

SEMI!VIDA DE ELIMINACIN 91!4? ORAS

BIODISPONIBILIDAD ;0F

CONCENTRACIN PLASMTICA 91! 2? '#$)ALIMENTOS ANTICIDOS DISMINUKEN ABSORCIN

UNIN A PROTE"NAS PLASMTICAS DE HORMA IMPORTANTE

VOLUMEN DE DISTRIBUCIN VARIABLE DEPENDE DEL HCO

BARRERA EMATOENCEHLICA ATRAVIESAN CON HACILIDADSE EXCRETAN POR LECE MATERNA

IMAOS MAS ANTIUOS NO TIENEN

METABOL"TOS

CONSI.

HCOLOIC.

IMAO


33/53

IMAO

FCO. NO

MODIFICADO

FCO

BIOTRANS

FORMADO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

IMAO


34/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

1 HAMILIAA SUBTIPO2 PRODUCTO ENRICO

IMAO


35/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

1 DE CG20

IMAO


36/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 67;

>!IDROXITRIPTAMINA

http://smb//commons.wikimedia.org/wiki/File:Serotonin-Spartan-HF-based-on-xtal-3D-balls-web.pnghttp://smb//commons.wikimedia.org/wiki/File:Serotonin-Spartan-HF-based-on-xtal-3D-balls-web.png


37/53





38/53



IMAO. MECANISMO DE ACCIN


39/53




40/53


T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. 677

IMAO


41/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

IMAO


42/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

IMAO


43/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

IMAO


44/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

IMAO


45/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

IMAO


46/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

IMAO


47/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

IMAO


48/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

IMAO


49/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

IMAO


50/53

IMAO

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5

IMAO


51/53

T#$%$&' &( P)*+'$#-$+''/$. S$$$#, P(#$%$, P$)%'#. 2 (&. T'-' 3. C$ 55. P/. >;5


52/53


53/53

antidepresivos triciclicos.ppt

Documents