Newsflash September 2014

New Products

Veterinary antibodies

New Antibody Data

ST2 recombinant Fabs

CRP recombinant Fabs

Capabilities

Monoclonal antibodies

Polyclonal antibodies

Recombinant Fab antibodies

Quality InnovationResultsPartnership

Be confident in your results when you

choose BBI’s monoclonal antibodies for

your next assay:

Tested in ELISA

Tested in lateral flow

Recommended pairings provided

Strong customer feedback

We have now introduced highly sensitive

recombinant Fab antibodies to improve

your next generation assays.

New this month – new veterinary

antibodies for companion and livestock

animals.

Why choose BBI?

Quick Links

NEW

Veterinary Antibodies >

ST2 ELISA Data >

CRP Affinity Data >

Monoclonal Antibodies >

Polyclonal Antibodies >

Recombinant Fab

Antibodies >

How to Order >

NEW Veterinary Antibodies

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New range of veterinary antibodies targeted to a variety of companion and

livestock animals.

Tested in lateral flow with recommended matched pairings.

Marker Capture Antibody Detection Antibody

CDV (Canine Distemper Virus) BM417-D1A6 BM417-D1A6

Avian Influenza Virus H5 BM422-Z3D1 BM422-P6H1

FeLV BM419-E7A5 BM419-O6H1

Brucella LPS BM420-G9E1 BM420-M9D1

Giardia BM423-V5C5 BM423-V5C5

Enrofloxacin BM427-Z6C6 BM427-Z6C6

Goat IgG BM418-G7B1 or BM418-K5D1 BM418-G7B1 or BM418-K5D1

Canine IgM BM424-S6B1

BM424-T7H1

BM424-T7H1

BM424-S6B1

Swine IgG BM425-S6H4

Chicken IgY BM421-P5G5 or BM421-M6B6 BM421-M6B6 or BM421-P5G5

GST (Glutathione S-transferase) BM426-H9E9

NEW Veterinary Antibodies

Avian Influenza Virus H5 Strain Antibody

Marker Capture

Antibody

Detection

Antibody

Avian Influenza

Virus H5

BM422-Z3D1 BM422-P6H1

Proven performance in lateral flow

The image shows BM422-Z3D1 as capture antibody

and BM422-P6H1 as detection antibody in a

sandwich assay format.

This antibody pair is able to detect all H5 subtypes

of Avian Influenza Virus.

Lane 1 – Cultured Avian Influenza Virus

Lane 2 – Buffer only

1 2

The H5 strain of Avian Influenza is

currently prevalent in Europe and

Asia, where there are 9 known

subtypes.

Images have not been altered for brightness or contrast. The antibody is not self-pairing.

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NEW Veterinary Antibodies

Giardia Antibody

Marker Capture

Antibody

Detection

Antibody

Giardia BM423-V5C5 BM423-V5C5

Proven performance in Lateral Flow

The image shows BM423-V5C5 used as both a

capture and detection antibody to detect Giardia in a

sample from an infected dog.

The antibody is self-pairing.

Lane 1 – Giardia-infected dog stool sample

Lane 2 – Buffer only

1 2

Giardia is a parasite of the intestine

affecting both domestic and wild

animals along with humans.

Images have not been altered for brightness or contrast. The antibody is not self-pairing.

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Antibody Spotlight New Data – ST2 recombinant Fab

Recommended for use within ELISA.

Provided with recommended pairings and range of detection.

Capture Antibody Detection Antibody Range of Detection

BR139-S7B7 BR139-V8D4 1.39 – 97 ng / ml

BR139-T3G5 BR139-V8D4 0.08 – 31 ng / ml

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Antibody Spotlight New Data – CRP recombinant Fab affinity data

Biotinylated antigen was immobilised onto a streptavidin sensor. Ka, Kd and KD

measured on the Octet system.

Our CRP recombinant Fab antibody has a picomolar affinity of 139pm.

70.5 nM

35.2 nM

17.6

nM

8.81

nM

KD (nM)

0.138

Kon (1/Ms)

233400 ± 275

Kdis (1/s)

3.23 x 10-5 ±

1.78 x 10-7

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Our Capabilities | Monoclonal Antibodies

Cardiac Infectious Disease Norovirus Pregnancy

CK-MB C. difficile Toxin A PBP2a AFP

D-Dimer C. difficile Toxin B TB

Myoglobin Chikungunya Veterinary

Troponin I Dengue NS1 Tumour Canine Distemper

H. pylori CA125 Virus

Diabetes HAV CA15-3 Avian Influenza H5

Hb HBV CA19-9 FeLV

HbA1c Hepatitis B Calcitonin Brucella LPS

HIV p24 Enrofloxacin

Drugs of abuse HIV gp35 Immunoglobulins Goat IgG

THCΔ9 HIV gp41 IgA Canine IgM

Influenza A IgE Chicken IgY

Hormones Influenza B IgG GST

Progesterone Leptospira IgM

PTH Listeria

Malaria HRP2

Malaria LHD (pan)

Malaria LHD (Pf)

Malaria LDH (Pf & Pv) Return home >

Our Capabilities | Polyclonal Antibodies

Inflammation Pregnancy Renal

CRP AFP A2M

B2M

Hormones Inflammatory Cystatin C

HCG A1AT

αHCG

Haematology Metabolism

Immunoglobulins Haptoglobin Ceruloplasmin

IgA Ferritin

IgM Haemoglobin

IgG

Albumin

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Our Capabilities | Recombinant Fab Antibodies

* Detection Ranges are assay dependent and optimised for specific

clinical conditions, therefore may be improved with optimisation

Biomarker Detection Range* Capture Antibody Detection Antibody

HSP60 0.1 - 1200 ng/mL BR100-G2A7 BR100-H4C2

Adiponectin 0.1 - 525 ng/mL BR101-P7E2 BR101-M3H8

Adiponectin 230 - 59118 ng/mL BR101-H2B4 (Competitive ELISA)

Angiopoietin 2 0.001 - 97 ng/mL BR103-P4E8 BR103-V5F2

Big Endothelin 1 0.001 - 1.8 ng/mL BR104-D6A4 BR104-H1A4

Calcitonin 0.006 - 2 ng/mL BR388-G6B1 BR388-D5C4

Cathepsin D 0.03 - 150 ng/mL BR107-F5G2 BR107-K6D3

Eotaxin 0.007 - 2 ng/mL BR108-M7H3 BR108-K2D9

Chondrolectin 0.9 - 21 ng/mL BR111-P8G3 BR111-T6B1

CKBB 0.15 - 33 ng/mL BR112-V6F6 BR112-Z1C4

Proinsulin C-Peptide 0.09 - 38 ng/mL BR143-G5D3 BR143-K7C9

CRP 151 - 231000 ng/mL BR228-D4A3 (Competitive ELISA)

Cystatin C 165 - 9073 ng/mL BR175-G8D9 (Competitive ELISA)

Cystatin C 165 - 9073 ng/mL BR175-H4C8 (Competitive ELISA)

E. histolytica not tested BR116-K9F7 BR116-G3A1

E-selectin 0.05 - 235 ng/mL BR117-K2E7 BR117-H5B6

FABP Intestine 0.65 - 100 ng/mL BR115-F7G7 BR115-G6B9

FABP Liver 0.03 - 90 ng/mL BR106-G5A2 BR106-P9F5

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Our Capabilities | Recombinant Fab Antibodies

* Detection Ranges are assay dependent and optimised for specific

clinical conditions, therefore may be improved with optimisation

Biomarker Detection Range* Capture Antibody Detection Antibody

G. lamblia not tested BR120-P3F2 & BR120-T1G8

Human Fetal Hemoglobin 1.9 - 305 ng/mL BR121-T5H9 BR121-V5A7

Leptin 3.9 - 691 ng/mL BR123-M4D6 BR123-P4G2

MMP7 0.1 - 293 ng/mL BR124-S4E3 BR124-T6G8

MMP9 Active 11 - 183 ng/mL BR125-N5F7 BR125-M6D6

MPO 2 - 1200 ng/mL BR240-N5G6 BR240-D8B4

Neutrophil Elastase 0.008 - 33 ng/mL BR127-H2A4 BR127-G7C2

Free PAPP A 0.3 - 299 ng/mL BR129-M5E3 BR129-F2H4

Pentraxin 3 4.6 - 876 ng/mL BR130-H2C3 BR130-K6D6

PGDS 0.2 - 85 ng/mL BR131-M6H7 BR131-P7F7

PSAP A 0.013 - 123 ng/mL BR132-T5G4 BR132-S6E4

PSAP B 0.3 - 1500 ng/mL BR133-V6B5 BR133-V4D1

RBP 4 350 - 500000 ng/mL BR134-Z7D3 (Competitive ELISA)

S100 Beta 0.04 - 5.6 ng/mL BR332-G4B9 BR332-F5H7

ST2 1.39 - 97 ng/mL BR139-S7B7 BR139-V8D4

ST2 0.08 - 31 ng/mL BR139-T3G5 BR139-V8D4

Tie2 0.8 - 600 ng/mL BR140-Z7A5 BR140-D9D7

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How to Order

Please get in touch to arrange a quote for

any of our products.

You can also order directly via our website

www.bbisolutions.com

info@bbisolutions.com

USA: 1-800-423-8199

Intl: +44 (0) 2920 747 232

Quote on ordering – NF SEP

BBI Solutions

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BBI Solutions

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