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Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June H. Myklebust, Bindu Varghese, Saar Gill, Max Jan, Adriel C. Cha, Charles K. Chan, Brent T. Tan, Christopher Y. Park, Feifei Zhao, Holbrook E. Kohrt, Raquel Malumbres, Javier Briones, Randy D. Gascoyne, Izidore S. Lossos, Ronald Levy, Irving L. Weissman, Ravindra Majeti Cell Volume 142, Issue 5, Pages 699-713 (September 2010) DOI: 10.1016/j.cell.2010.07.044 Copyright © 2010 Elsevier Inc. Terms and Conditions

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Page 1: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma 

Mark P. Chao, Ash A. Alizadeh, Chad Tang, June H. Myklebust, Bindu Varghese, Saar Gill, Max Jan, Adriel C. Cha, Charles K. Chan, Brent T. Tan, Christopher Y. Park, Feifei Zhao, Holbrook E. Kohrt, Raquel Malumbres, Javier Briones, Randy D. Gascoyne, Izidore S.

Lossos, Ronald Levy, Irving L. Weissman, Ravindra Majeti 

Cell Volume 142, Issue 5, Pages 699-713 (September 2010)

DOI: 10.1016/j.cell.2010.07.044

Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 2: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure 1

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 3: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure 2

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 4: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure 3

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 5: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure 4

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 6: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure 5

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 7: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure 6

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 8: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure 7

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 9: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure S1

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 10: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure S2

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 11: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure S3

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 12: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure S4

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 13: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure S5

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 14: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure S6

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 15: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Figure S7

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions

Page 16: Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma Mark P. Chao, Ash A. Alizadeh, Chad Tang, June

Cell 2010 142, 699-713DOI: (10.1016/j.cell.2010.07.044) Copyright © 2010 Elsevier Inc. Terms and Conditions