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DIVISION OF BIOSTATISTICS ANNUAL UPDATE 2017 - 18

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  • DIVISION OF BIOSTATISTICS ANNUAL UPDATE 2017 - 18

  • Page 2 of 36

    TABLE OF CONTENTS

    EXECUTIVE SUMMARY ................................................................................................................................ 3

    BIOSTATISTICS NEWS .................................................................................................................................. 4

    BIOSTATISTICS FACULTY .............................................................................................................................. 5

    BIOSTATISTICS STAFF .................................................................................................................................. 6

    METHODOLOGIC RESEARCH ....................................................................................................................... 7

    COLLABORATIVE APPLIED RESEARCH ....................................................................................................... 10

    BIOSTATISTICS CONSULTING SERVICE ...................................................................................................... 11

    2017 FUNDED GRANTS .............................................................................................................................. 12

    2018 FUNDED GRANTS .............................................................................................................................. 15

    APPENDIX 1: PRESENTATIONS .................................................................................................................. 19

    APPENDIX 2: COLLABORATIVE PAPERS & PUBLICATIONS ....................................................................... 21

  • Page 3 of 36

    EXECUTIVE SUMMARY

    This document summarizes the activities of the Division

    of Biostatistics in the Institute for Health & Equity of the

    Medical College of Wisconsin for 2017 and 2018.

    The division supports the missions of the Medical College

    of Wisconsin through its graduate and continuing medical

    professional training in biostatistics; its support of funded

    research projects bringing in over $140 million external funds

    in 2017 and $169 million external funds in 2018 to MCW; its

    prominence in the development of novel statistical methods

    for biomedical data; and its biostatistical consulting service.

    In 2017, we co-authored 73 papers including four papers in high

    impact journals (New England for Journal of Medicine, Journal

    of Clinical Oncology), helped investigators apply successfully

    for 18 new grants worth $13.9 million, and collaborated on over 397 projects through the Biostatistics

    Consulting Service. In 2018, we co-authored 160 papers including six papers in high impact journals,

    (British Journal of Hematology, Lifetime Data Analysis, Statistics in Medicine, The American

    Statistician), helped investigators apply successfully for 21 new grants worth $34.6 million, and

    collaborated on 341 projects through the Biostatistics Consulting Service.

    The division faculty has active research programs in various areas of biostatistics. The division is

    recognized worldwide for its research in survival analysis. Other areas of investigation include statistical

    genetics, Bayesian statistics, big data methods, design and analysis of clinical trials, and multiple

    comparisons. The division faculty had 13 methodological papers in 2017 and 20 methodological papers

    in 2018 that appeared in statistical literature either as an online publication or in print (See Appendix 1).

  • Page 4 of 36

    BIOSTATISTICS NEWS

    Two new faculty joined the division in 2017:

    Chien-Wei (Masaki) Lin completed his PhD in Biostatistics from the University

    of Pittsburgh; he has expertise and research interests in bioinformatics and the analysis

    of different types of -omics data.

    Noorie Hyun joined us after completing a PhD in Biostatistics at the University of North

    Carolina and a post-doctoral fellowship at the Division of Cancer Epidemiology and

    Genetics at the National Cancer Institute. She has research interests in the analysis of

    time-to-event data, complex probability sampling, and synthesis of information from

    electronic health records to enhance statistical inference.

    We also hired three new analysts, Kadam Patel, Xuerong (Joy) Liu, and Ruizhe (Rachel) Wu in 2018, and

    said goodbye to one of our analysts, Ziyan Yin, who left to pursue a PhD in Biostatistics. Jennifer Ward

    joined the division in early 2018 as a Research Program Coordinator II, after our prior Program

    Coordinator Tiara Cargile left for another opportunity.

    Several faculty members received grants as PIs to support their biostatistical methodologic research.

    Drs. Ahn and Kim were awarded an Advancing a Healthier Wisconsin-Research and Education Program

    grant in 2017, titled “Optimal conditioning regimen intensity for competing risks data in myelodysplastic

    syndromes.” Dr. Kim also received Cancer Center pilot funding in 2017 for a project titled, “Variable

    selection for the case cohort design with multiple diseases.” Dr. Banerjee received CTSI Pilot funding in

    2018 as the PI of a project titled, "Ensemble learning integrated with cancer survivor intervention," and

    also received an R21 grant from the NCI in 2018 entitled, "Bayesian learning algorithms for identifying

    and classifying heterogeneity of cell types in variety of solid tumors."

    Four PhD students successfully defended their dissertations, Michael Martens and Yushu Shi in 2017 and

    Bonifride Tuyishimire and Natasha Sahr in 2018,

    Several of our division faculty members were involved in notable high impact publications.

    2017

    • Drs. Zhang, Banerjee, and Logan in the Journal of Clinical Oncology

    • Dr. Wang in the New England Journal of Medicine

    2018

    • Dr. Fraser in the Journal of Clinical Oncology

    • Dr. Szabo in JAMA Oncology

    In Fall 2017, we organized and hosted a National Conference titled, “Biostatistics in the Modern

    Computing Era.” It was extremely successful, drawing 125 attendees to attend talks in areas including

    high-dimensional analysis, precision medicine, genomic data analysis, Bayesian modeling and clinical

    trials. At the end of the conference, Dr. Sparapani co-led an all-day workshop on Bayesian Additive

    Regression Trees (BART) for 45 attendees.

    Kadam Patel Xuerong (Joy) Liu Ruizhe (Rachel) Wu Jennifer Ward

  • Page 5 of 36

    BIOSTATISTICS FACULTY

    Anjishnu Banerjee, PhD

    Assistant Professor

    of Biostatistics

    Brent Logan, PhD

    Director & Professor

    of Biostatistics

    Prakash Laud, PhD

    Professor of Biostatistics

    Mei-Jie Zhang. PhD

    Professor of Biostatistics

    Kwang Woo Ahn, PhD

    Associate Professor

    of Biostatistics

    Ruta Brazauskas, PhD

    Associate Professor

    of Biostatistics

    Raphael Fraser, PhD

    Assistant Professor

    of Biostatistics

    Noorie Hyun, PhD

    Assistant Professor

    of Biostatistics

    Aniko Szabo, PhD

    Associate Professor &

    Director of Biostatistics

    Consulting Service

    Soyoung Kim, PhD

    Assistant Professor

    of Biostatistics

    Masaki Lin, PhD

    Assistant Professor

    of Biostatistics

    Ying Liu, PhD

    Assistant Professor

    of Biostatistics

    Rodney Sparapani, PhD

    Assistant Professor

    of Biostatistics

    Sergey Tarima, PhD

    Associate Professor of

    Biostatistics

    Tao Wang, PhD

    Associate Professor

    of Biostatistics

  • Page 6 of 36

    BIOSTATISTICS CONSULTING ANALYSTS

    BIOSTATISTICS ADMINISTRATIVE SUPPORT

    Jennifer Ward

    Research Program

    Coordinator II

    Kellie Bialzik, MBA

    Business Manager, Sr.

    Alexis Visotcky, MS

    Biostatistics Analysts II

    Ziyan Yin, MS

    Biostatistics Analysts I

    Dan Eastwood, MS

    Biostatistics Analysts II

    Joy Liu, MS

    Biostatistics Analysts I

    Kadam Patel, MPH

    Biostatistics Analysts I

    Lisa Rein, MS

    Biostatistics Analysts II

    Rachel Wu, MS

    Biostatistics Analysts I

  • Page 7 of 36

    METHODOLOGIC RESEARCH

    The division faculty has active research programs in various areas of biostatistics. The division is recognized worldwide

    for its research in survival analysis. Other areas of investigation include statistical genetics, Bayesian statistics, big data

    methods, design and analysis of clinical trials, and multiple comparisons. The division faculty had 13 methodological

    papers in 2017 and 20 in 2018 that appeared in statistical literature either as an online publication or in print. (See list

    below). In addition to publications, the Division of Biostatistics also presented 0ten methodological

    presentations/abstracts in 2017 and 10 in 2018. (See Appendix 1).

    2017

    Ahn KW, et al. (2017). "Group and within-group variable selection for competing risks data." Lifetime Data Analysis

    24(3): 407-424.

    Cheung LC, et al. (2017). "Mixture models for undiagnosed prevalent disease and interval‐censored incident disease:

    applications to a cohort assembled from electronic health records." Statistics in Medicine 36(22): 3583-3595.

    Hyun N., et al. (2017). "Flexible risk prediction models for left or interval-censored data from electronic health records."

    Ann. Appl. Stat. 11(2): 1063-1084.

    Kim S and Huang Y. (2017). "Combining biomarkers for classification with covariate adjustment." Statistics in

    Medicine 36(15): 2347-2362.

    Krakow EF, et al. (2017). "Tools for the Precision Medicine Era: How to Develop Highly Personalized Treatment

    Recommendations from Cohort and Registry Data Using Q-Learning." American Journal of Epidemiology

    186(2): 160-172.

    Liu J, et al. (2017). "A Bayesian subgroup analysis using collections of ANOVA models." Biom J 59(4): 746-766.

    Liu Y, et al. (2017). "Sequential multiple assignment randomization trials with enrichment design." Biometrics 73(2):

    378-390.

    Liu Y, et al. (2017). "Deep Reinforcement Learning for Dynamic Treatment Regimes on Medical Registry Data."

    Healthcare Informatics 380-385.

    Liu Y, et al. (2017). "Estimating personalized diagnostic rules depending on individualized characteristics." Statistics in

    Medicine 36(7): 1099-1117.

    Logan BR, et al. (2017). "Decision making and uncertainty quantification for individualized treatments using Bayesian

    Additive Regression Trees." Statistical Methods in Medical Research: 0962280217746191.

    Tarima S. (2017). "Statistical estimation in the presence of possibly incorrect model assumptions." Journal of Statistical

    Theory and Practice 11(3): 449-467.

    Szabo A. (2017). "Test for Trend with a Multinomial Outcome." The American Statistician: 1-8.

    Zheng C, et al. (2017). "Instrumental variable with competing risk model." Statistics in Medicine 36(8): 1240-1255.

  • Page 8 of 36

    2018

    Ahn KW, Banerjee A, Sahr N, and Kim S, et al. (2018). "Group and within-group variable selection for competing risks

    data." Lifetime Data Analysis 24(3): 407-424.

    Ahn KW, Sahr N, Kim S, et al. (2018). "Screening group variables in the proportional hazards model." Statistics &

    Probability Letters 135: 20-25. Ahn KW, Kim S, et al. (2018). "Variable selection with group structure in

    competing risks quantile regression." Statistics in Medicine 37(9): 1577-1586.

    Szabo A. (2018). "Test for Trend with a Multinomial Outcome AU - Szabo, Aniko." The American Statistician: 1-8.

    Banerjee A, DeVogel N, Pintar F, et al. (2018). "Novel learning framework (knockoff technique) to evaluate metric

    ranking algorithms to describe human response to injury AU - Banerjee, Anjishnu." Traffic injury prevention:

    1-6.

    DeVogel N, Banerjee A, Yoganandan N, et al. (2018). "Application of resampling techniques to improve the quality of

    survival analysis risk curves for human frontal bone fracture." Clinical Biomechanics.

    Hyun N, Gastwirth JL, Graubard BI. (2018). "Grouping methods for estimating the prevalences of rare traits from

    complex survey data that preserve confidentiality of respondents." Statistics in Medicine 37(13): 2174-2186.

    Hyun N, Zang D, et al. (2018). "Semiparametric additive model for estimating risk difference in multicenter studies AU

    - Zeng, Donglin." Biostatistics & Epidemiology 2(1): 84-98.

    Kim S, Zeng D, Cai J, et al. (2018). "Analysis of multiple survival events in generalized case-cohort designs."

    Biometrics 0(0).

    Kim S and Ahn KW, et al. (2018) "Bi-level variable selection for case-cohort studies with group variables." Statistical

    Methods in Medical Research. In press.

    Lin CW, Liao SG, Liu P, Ting Lee ML, et al. (2018) "RNASeqDesign: a framework for ribonucleic acid sequencing

    genome wide power calculation and study design issues." Journal of the Royal Statistical Society: Series C

    (Applied Statistics) 0(0).

    Liu N, Liu Y, Logan BR, Xu Z, Tang J, Wang Y. (2018). "Deep Reinforcement Learning for Dynamic Treatment

    Regimes on Medical Registry Data." Healthcare Informatics 2017: 380-385.

    Liu Y, Wang Y, Kosorok M, Zhao Y, Zeng D. (2018). "Augmented outcome-weighted learning for estimating optimal

    dynamic treatment regimens." Statistics in Medicine 37(26): 3776-3788.

    Logan BR, Martens MJ. (2018). "A group sequential test for treatment effect based on the Fine-Gray model."

    Biometrics 0(0).

    Logan BR, Sparapani R, McCulloch RE, Laud PW, et al. (2018). "Decision making and uncertainty quantification for

    individualized treatments using Bayesian Additive Regression Trees." Statistical Methods in Medical Research:

    0962280217746191.

    Ma T, Huo Z, Kuo A, Zhu L, Fang Z, Zeng X, Lin CW, et al. (2018). "MetaOmics: analysis pipeline and browser-based

    software suite for transcriptomic meta-analysis."

    Sparapani RA, Tarima SS, Jackson TA, Meurer JR, et al. (2018). "Non-parametric recurrent events analysis with BART

    and an application to the hospital admissions of patients with diabetes." Biostatistics: kxy032-kxy032.

    Tarima S, Tarassenko P, Tuyishimire B, Sparapani R, et al. (2018). Signs of Residuals for Testing Coefficients in

    Quantile Regression. Cham. Springer International Publishing.

    METHODOLOGIC RESEARCH

  • Page 9 of 36

    Wang Y, Logan BR. (2018). "Testing for center effects on survival and competing risks outcomes using pseudo-value

    regression." Lifetime Data Analysis.

    Yoganandan N, Banerjee A, DeVogel N, Pintar FA, Baisden JL, et al. (2018). "A Novel Competing Risk Analysis

    Model to Determine the Role of Cervical Lordosis in Bony and Ligamentous Injuries." World Neurosurgery

    119: e962-e967.

    Shi Y, Martens M, Anjishnu B, Laud P, et al. (2018). "Low Information Omnibus (LIO) Priors for Dirichlet Process

    Mixture Models." Bayesian Anal.

    METHODOLOGIC RESEARCH

  • Page 10 of 36

    COLLABORATIVE APPLIED RESEARCH

    The Division of Biostatistics provides biostatistical support for collaborative applied research through three

    mechanisms:

    1. As co-investigators on grants

    2. Through an integration contract set up with Medical College departments, division, centers, institutes,

    or other research programs to provide upfront integrated biostatistical support to their members

    3. Through the hourly effort recharge mechanism of the Biostatistics Consulting Service.

    Faculty and analysts in the Division of Biostatistics co-authored 230 medical publications in the past two years – 73

    papers in 2017 and 160 in 2018. During these two years, they also provided statistical support through major grant

    effort for integration contract for the following research programs:

    • The Center for Advancing Population Sciences (CAPS)

    • Center for Aids Intervention Research (CAIR)

    • The Center for International Blood & Marrow Transplant Research (CIBMTR)

    o Resource for Clinical Investigation in Blood and Marrow Transplantation (RCI BMT)

    o Blood and Marrow Transplant Clinical Trials Network (BMT CTN)

    o National Marrow Donor Program / Be the Match

    • The Clinical & Translational Science Institute (CTSI), through June 2017

    • The Cardiovascular Center (CVC)

    • The Medical College of Wisconsin Cancer Center

    • The Department of Medicine, through June 2018

    • The Neuroscience Research Center

    • The Department of Orthopedic Surgery

    • The Department of Physical Medicine and Rehabilitation

    • Pediatric Emergency Medicine

    • Department of Pediatrics (support for genomics researchers)

    • The Department of Surgery

    • The Division of Hematology / Oncology in the Department of Medicine

    • Froedtert Hospital Pharmacy

  • Page 11 of 36

    BIOSTATISTICS CONSULTING SERVICE

    The Biostatistics Consulting Service (BCS) provides statistical support to investigators at the Medical College, its affiliates

    and the general public. The services provided include assistance with study design, data management, statistical analysis,

    interpretation of study results and assistance in grant preparation. This pre-arranged assistance is available through the BCS

    on a recharge basis or through pre-arranged contracts with Departments or Centers as described previously.

    The BCS collaborated on 397 (2017) and 341 (2018) projects, totaling 738 projects and 9,401 hours with Biostatistics Faculty

    and Analysts collaborating time. Following is a breakdown of projects per MCW department or other affiliation.

    The BCS provides drop-in consulting hours per week, similar to “faculty office hours” where staff biostatisticians designate

    weekly hours specifically available to investigators for free statistical consultations. To learn more, view the Biostatistics

    Consulting Service website.

    BIOSTATS CONSULTING SERVICE NUMBER OF PROJECTS

    Department Name 2017 2018

    Anesthesiology 3 1

    Biochemistry 3 3

    Biomedical Engineering 2 0

    Cell Bio, Neuro & Anat 2 5

    Dermatology 0 1

    Emergency Medicine 4 1

    Family & Comm. Med 4 4

    IHE 4 3

    Medicine 149 126

    Micro & MGenetics 4 6

    Neurosurgery 1 4

    OBGYN 6 0

    Ophthalmology 12 9

    Orthopaedic Surgery 26 20

    Otolaryngology 8 10

    Pathology 6 8

    Pediatrics 21 17

    Pharm & Tox 9 9

    PMR 13 10

    Plastic Surgery 1 3

    Psy & Behav Med 2 1

    Radiation Oncology 18 6

    Radiology 6 4

    School of Phar 1 0

    Surgery 88 86

    Urology 4 4

    Totals 397 341

    https://www.mcw.edu/Biostatistics-Consulting-Service.htmhttps://www.mcw.edu/Biostatistics-Consulting-Service.htm

  • Page 12 of 36

    2017 FUNDED GRANTS

    Biostatistics

    Member Grant Title

    Direct Cost All

    Years

    Laud, Zhang,

    Banerjee Eastwood, AHW prevention, control, and population sciences $ 4,530,146

    ^Zhang

    A prospective cohort study comparing outcomes of patients receiving

    hematopoietic stem cell transplantation for hematologic malignancies with and

    without Kepivance

    $ 8,115,594

    Ahn, Kim, Wang,

    Logan, Zhang Stem cell therapeutic outcomes database $ 16,725,822

    ^Ahn, Logan,

    Fraser, Brazauskas,

    Zhang, Wang, Kim

    A data resource for analyzing blood and marrow transplants $ 14,515,155

    ^Sparapani Effect of ACA Medicaid, expansion on diabetes, diagnosis, treatment, patient

    compliance and health outcomes $ 33,208

    ^Logan, Fraser BMT clinical trials network data coordinating center $ 58,270,570

    ^Wang Hematopoietic stem cell and cord transplantation $ 82,681 ^Wang NK cells, their receptors and unrelated donor transplant $ 47,215 ^Wang National Bone Marrow Donor Program $ 68,960 ^Brazauskas National Bone Marrow Donor Program $ 18,991 *^Liu National Bone Marrow Donor Program $ 48,528

    ^Zhang Targeting p38gamma for the treatment of triple negative breast $ 698,568

    Ahn Maternal/Child Mental Health $ 191,044 ^Ahn National Bone Marrow Donor Program $ 4,729 ^Logan, Brazauskas National Bone Marrow Donor Program $ 70,000

    ^Ahn Endothelial function in human diabetes: role of mitochondrial fission proteins $ 1,994,764

    ^Fraser, Eastwood BMT clinical research network data coordinating center-supplement $ 4,006,680

    ^Logan, Yin Primary immune deficiency disease treatment consortium $ 427,646

    ^Tarima, Szabo,

    Banerjee Clinical and Translational Research Institute $ 2,398,403

    ^Laud Mechanisms of SES disparities in adherence to oral hormonal therapy for breast

    cancer $ 1,616,877

    Tarima Use of Mechanism of Injury for the Identification of Severely Injured Children $ 1,439,035

    Sparapani, Tarima Population Health Improvement for Patients and Employees with Diabetes $ 1,800,000 ^Vistocky Kohl's Healthy Families - Breast Cancer Physical Activity Program $ 50,000 ^Laud Mechanisms Underlying SES Disparities in Breast Cancer Mortality $ 674,596

    * Denotes New Grants | ^ Denotes External Funding

  • Page 13 of 36

    Biostatistics

    Member Grant Title

    Direct Cost All

    Years ^Laud Individualized Care Plans for Hematopoietic Cell Transplant Service $ 109,128 *^Logan, Banerjee Inhibition of oral tumorigenesis by Antitumor B $ 2,091,795

    Banerjee, Student Bayesian Ensemble Prediction for Identifying and Classifying Heterogeneity of

    Cell Types in Prostate Cancer $ 100,000

    Tarima High-Impact Integrated Behavioral and Biomedical Interventions to Eradicate

    AIDS $ 999,395

    Sparapani,

    Vistocky Cardiovascular Roadmap: Bridging our Foundation to Signature Programs $ 17,044

    ^Logan, Martens Competing Risks Analysis Methods for Group Sequential and Adaptive Designs $ 87,152

    ^Ahn, Visotcky KIR-Favorable Haploidentical Transplantation in Children $ 87,841

    Banerjee Human Injury Tolerance Toward Development and Validation of a Warrior

    Manikin $ 3,476,148

    ^Laud Creating Virtual Surgery Targets & Methods to Improve Outcomes of Nasal

    Surgery $ 1,011,572

    ^Laud (PQE3) A Statewide RCT to reduce use of ineffective or unproven breast cancer

    care $ 2,083,763

    ^Szabo Development of Lisinopril for Post-Exposure Mitigation of Late Radiation

    Injuries $ 438,295

    ^Szabo Mechanisms of upper gut and airways interaction program project grant $ 892,814

    ^Tarima Center for Aids intervention research $ 179,238

    Tarima High-Impact Integrated Behavioral and Biomedical Interventions to Eradicate

    AIDS $ 999,395

    ^Tarima Social Network Intervention to engage out of care PLH into treatment $ 2,238,040

    ^Tarima Increasing PrEP Use in High Risk Social Networks of African American MSM

    in underserved Low Intake Cities $ 3,500,177

    ^Tarima Reaching and engaging community PLH into care through their social network $ 449,620

    ^Zhang Stopping Tyrosine Kinase Inhibitors in CML patients (stop-TKI) $ 2,882,360

    ^Laud, Wang Ensemble Prediction Models for Personalized Therapy $ 228,532 ^Wang Pirches Study $ 113,889

    Szabo Acute Neurocognitive affective predictors of chronic post trauma outcomes $ 189,862

    ^Logan DISCIS (DISContinuation of Immune Suppression after hematopoietic cell

    transplant) Study $ 184,195

    Banerjee, Visotcky

    Moving forward: a weight loss intervention of African breast cancer survivors

    this RCT explores the effectiveness of a 6-month community-based weight loss

    intervention for African-American breast cancer survivors

    $ 68,463

    Szabo Tocilizumab for the prevention of acute graft versus host disease $ 150,000

    *Liu, Rein Born Learning: Portage County Rural Community Collaboration for Optimal

    Child Development $ 350,000

    *^Banerjee Development of Charlotte, Houston and Milwaukee Prehospital Research Node $ 2,042,754 ^Szabo Concussive Injury: Role of sleep restriction sleep aids, sedation and Caffeine $ 158,355

    2017 FUNDED GRANTS

    * Denotes New Grants | ^ Denotes External Funding

  • Page 14 of 36

    Biostatistics

    Member Grant Title

    Direct Cost All

    Years

    Tarima Engagement in care of older, rural, HIV+Adult $ 422,000

    *Sparapani Developing nicorandil and companion biomarkers for DMD cardiomyopathy

    therapy $ 1,773,020

    *Liu Magenta $ 247,018 *Brazauskas Treosulfan Matched Comparison $ 138,499

    ^Laud Racism, Residential Racial Segregation, Breast Cancer Survival Disparities

    among Black, Hispanic and non-Hispanic White Women $ 1,919,526

    *^Logan Biomarkers for risk of chronic Graft-Versus-Host Disease Occurrence $ 39,508

    *^Logan Dose Finding Study of Busulfan for Newly Diagnosed Infants with SCID $ 119,721 ^Szabo, Patel Test of an Organizational Change Model in Dental Care Settings $ 206,717

    *^Szabo/Patel Dental service utilization for Foreign- and Native-born children in America $ 62,125

    *^Tarima Cohesion Mutations in Acute Myelogenous Leukemia $ 66,214 *Banerjee Brian Cancer Radio-Pathomics for Predicting Heterogeneous Cytology $ 1,250,000

    *Zhang A study of doxycycline organ response, and health-related quality of life in light

    chain amyloidosis $ 255,000

    *Kim, Xu - Student Variable selection for the case cohort design with multiple diseases $ 30,000

    *^Banerjee Avanzado Juntas: Adapting an evidence-based weight loss program for Hispanic

    Breast Cancer Survivor $ 373,135

    ^Banerjee, Visotcky Every Day Counts: A Lifestyle Program for Women with Metastatic Breast

    Cancer $ 282,626

    *^Wang Genetic epidemiology of hematopoietic cell transplant outcomes $ 30,725

    *^Fraser Gilead Protocol $ 47,948

    *Tarima, Sparapani,

    Patel, Liu

    REDIRECT (Research in Early Child Development to Improve Resiliency and

    Equity) $ 5,000,000

    Logan, Sparapani,

    Laud Ensemble Prediction Models for Personalized Therapy $ 200,000

    External Funds $ 140,830,797

    New Grants $ 13,965,990

    2017 Total of All Grants $ 155,422,821

    *Denotes New Grants ^Denotes External Funding

    2017 FUNDED GRANTS

    * Denotes New Grants | ^ Denotes External Funding

  • Page 15 of 36

    2018 FUNDED GRANTS

    Biostatistics

    Member Grant Title

    Direct Cost All

    Years

    Laud, Zhang,

    Banerjee Eastwood AHW prevention, control, and population sciences $ 4,530,146

    ^Zhang

    A prospective cohort study comparing outcomes of patients receiving

    hematopoietic stem cell transplantation for hematologic malignancies with and

    without Kepivance

    $ 8,115,594

    ^Ahn, Kim, Wang,

    Logan, Zhang Stem cell therapeutic outcomes database $ 22,558,121

    ^Ahn, Logan,

    Fraser, Brazauskas,

    Zhang, Wang, Kim,

    Liu

    A data resource for analyzing blood and marrow transplants $ 19,814,194

    ^Sparapani Effect of ACA Medicaid, expansion on diabetes, diagnosis, treatment, patient

    compliance and health outcomes $ 50,808

    ^Logan, Fraser BMT clinical trials network data coordinating center $ 47,759,831

    ^Wang Hematopoietic stem cell and cord transplantation $ 156,797

    ^Wang NK cells, their receptors and transplantation and Cancer Therapy - Core B $ 98,924

    ^Wang National Bone Marrow Donor Program $ 105,509 ^Liu National Bone Marrow Donor Program $ 48,528

    ^Zhang Targeting p38gamma for the treatment of triple negative breast $ 1,068,068

    Ahn Maternal/Child Mental Health $ 191,044 ^Logan, Brazauskas National Bone Marrow Donor Program $ 70,000

    ^Ahn Endothelial function in human diabetes: role of mitochondrial fission proteins $ 2,965,268

    ^Fraser, Eastwood BMT clinical research network data coordinating center-supplement $ 4,006,680

    ^Logan, Yin,

    Brazauskas, Patel,

    Liu, Wu

    Primary immune deficiency disease treatment consortium $ 653,508

    ^Laud Mechanisms of SES disparities in adherence to oral hormonal therapy for breast

    cancer $ 2,357,948

    ^Tarima Use of Mechanism of Injury for the Identification of Severely Injured Children $ 1,494,282

    Sparapani, Tarima Population Health Improvement for Patients and Employees with Diabetes $ 1,800,000 ^Logan, Banerjee Inhibition of oral tumorigenesis by Antitumor B $ 3,033,782

    Banerjee, Student Bayesian Ensemble Prediction for Identifying and Classifying of Cell Types in

    Prostate Cancer $ 100,000

    Tarima High-Impact Integrated Behavioral and Biomedical Interventions to Eradicate

    AIDS $ 999,395

    * Denotes New Grants | ^ Denotes External Funding

  • Page 16 of 36

    Biostatistics

    Member Grant Title

    Direct Cost All

    Years

    Sparapani,

    Visotcky Cardiovascular Roadmap: Bridging our Foundation to Signature Programs $ 4,000,000

    ^Ahn, Visotcky KIR-Favorable Haploidentical Transplantation in Children $ 87,841

    ^Banerjee Human Injury Tolerance Toward Development and Validation of a Warrior

    Manikin $ 648,879

    ^Laud Creating Virtual Surgery Targets & Methods to Improve Outcomes of Nasal

    Surgery $ 1,406,759

    ^Laud (PQE3) A Statewide RCT to reduce use of ineffective or unproven breast cancer

    care $ 617,350

    ^Szabo Development of Lisinopril for Post-Exposure Mitigation of Late Radiation

    Injuries $ 525,530

    ^Szabo Mechanisms of upper gut and airways interaction program project grant $ 1,135,722

    ^Tarima Center for Aids intervention research $ 1,175,701

    ^Tarima Social Network Intervention to engage out of care PLH into treatment $ 2,238,040

    ^Tarima Increasing PrEP Use in High Risk Social Networks of African American MSM

    in underserved Low Intake Cities $ 3,500,177

    ^Tarima Reaching and engaging community PLH into care through their social network $ 630,757

    ^Zhang Stopping Tyrosine Kinase Inhibitors in CML patients (stop-TKI) $ 3,357,153

    Laud, Wang Ensemble Prediction Models for Personalized Therapy $ 228,532

    ^Szabo Acute Neurocognitive affective predictors of chronic post trauma outcomes $ 272,033

    Liu, Rein Born Learning: Portage County Rural Community Collaboration for Optimal

    Child Development $ 350,000

    ^Banerjee Development of Charlotte, Houston and Milwaukee Prehospital Research Node $ 900,000 ^Szabo Concussive Injury: Role of sleep restriction sleep aids, sedation and Caffeine $ 1,179,747 ^Tarima Engagement in care of older, rural, HIV+Adult $ 420,750

    ^Sparapani Developing nicorandil and companion biomarkers for DMD cardiomyopathy

    therapy $ 1,769,940

    ^Liu Magenta $ 247,018 ^Brazauskas Treosulfan Matched Comparison $ 173,125

    ^Laud Racism, Residential Racial Segregation, Breast Cancer Survival

    Disparities among Black, Hispanic and non-Hispanic White Women $ 2,824,645

    ^Szabo, Patel Test of an Organizational Change Model in Dental Care Settings $ 206,717 ^Szabo/Patel Dental service utilization for Foreign- and Native-born children in America $ 62,125

    ^Tarima Cohesion Mutations in Acute Myelogenous Leukemia $ 66,214 ^Banerjee Brian Cancer Radio-Pathomics for Predicting Heterogeneous Cytology $ 1,915,820

    Zhang, Brazauskas A study of doxycycline organ response, and health-related quality of life in light

    chain amyloidosis $ 255,000

    2018 FUNDED GRANTS

    * Denotes New Grants | ^ Denotes External Funding

  • Page 17 of 36

    Biostatistics

    Member Grant Title

    Direct Cost All

    Years

    ^Kim, Xu - Student Variable selection for the case cohort design with multiple diseases $ 20,000

    ^Banerjee Avanzando Juntas: Adapting an evidence-based weight loss program for

    Hispanic Breast Cancer Survivor $ 429,107

    ^Banerjee, Visotcky Every Day Counts: A Lifestyle Program for Women with Metastatic Breast

    Cancer $ 373,046

    ^Wang Genetic epidemiology of hematopoietic cell transplant outcomes $ 46,314

    Tarima, Sparapani,

    Patel, Liu

    REDIRECT (Research in Early Child Development to Improve Resiliency and

    Equity) $ 5,000,000

    *^Brazauskas Plerixafor Prospective Registry Study $ 1,870,000

    *^Kim Rate and Characterization of VOD in Patients Who Received Mylotarg Pre-HCT $ 243,000

    *Ahn, Kim, Saber,

    He - Student

    Optimal Conditioning Regimen Intensity for Competing Risks data in

    myelodysplastic syndromes $ 200,000

    *^Ahn, Lin Rat Genome Database $ 8,582,554

    *Banerjee,

    Visotcky, Stolley CTSI Pilot: Ensemble Learning Integrated with Cancer Survivor Intervention $ 50,000

    *^Banerjee, Hall,

    Iczkowski, Koch,

    LaViolette, Keuter

    Bayesian learning algorithms for identifying and classifying heterogeneity of cell

    types in variety of solid tumors $ 368,445

    *^Brazauskas,

    Logan

    Prospective, Observational Long-Term, Non-Interventional Cohort Study of

    Recipients of Axicabtagene Ciloleucel for Treatment of Relapsed/Refractory

    Large B-Cell Lymphomas

    $ 5,020,000

    *^Brazauskas Treosulfan Matched Comparison $ 141,000

    *^Brazauskas Incorporating patient reported outcomes into individualized prognostication tools

    for survival and quality of life in transplant patients $ 247,546

    *^Fraser, Logan

    A Multi-center Randomized, Double-Blind, Placebo-controlled Phase III Trial of

    the FLT3 Inhibitor Gilteritinib Administered as Maintenance Therapy Following

    Allogeneic Transplant for Patients with FLT3/ITD AML

    $ 392,000

    *Fraser, Logan BMT/CTN 1803 $ 48,000

    *Laud Avoiding Health Disparities when collecting patients for Clinical care and

    Pragmatic Research $ 200,000

    *^Laud, Wang Renal Mechanisms in Blood Pressure Control $ 2,324,678 *Laud Collaborative for Population Health Improvement (C-PHI) $ 4,999,992

    *^Logan, Laud,

    Sparapani Machine Learning Strategies for Optimizing Donor Selection (BART Projects) $ 139,878

    *^Lin Investigating the role of the microbiome and inflammation in acute and chronic

    pain in patients with sickle cell disease $ 755,390

    *^Logan Randomized Study of very low versus low dose busulfan in transplant for serve

    combined $ 119,721

    2018 FUNDED GRANTS

    * Denotes New Grants | ^ Denotes External Funding

  • Page 18 of 36

    Biostatistics

    Member Grant Title

    Direct Cost All

    Years

    *^Logan Biomarkers for risk of chronic Graft-Versus-Host Disease occurrence $ 117,429

    *^Logan, Zhang Immuno-Oncology Translation Network (IOTN): Cellular Immunotherapy Data

    Resources (CIDR) $ 8,544,970

    *Logan, Laud,

    Sparapani, Shaw,

    Tuyishimire -

    Student

    Bayesian ensemble models for time to event data and individualized treatments $ 39,995

    *Tarima Illness Perception in Congestive Heart Failure $ 200,000

    External Funds $ 169,454,963

    New Grants $ 34,604,598 Total of All Grants $ 192,647,067

    * Denotes New Grants | ^ Denotes External Funding

    2018 FUNDED GRANTS

  • Page 19 of 36

    APPENDIX 1: METHODOLOGIC PRESENTATIONS

    2017

    Banerjee A, SAMSI workshop 2017, Durham, NC, Oct 2017.

    Brazauskas R. “Understanding Outcome Studies. World Marrow Donor Association search coordinators training

    program”, 2017.

    Brazauskas R. “Understanding Outcome Studies. Presented in a lecture series Current Topics in Histocompatibility and

    Transplantation. Audience: histocompatibility laboratory technologists including supervisors and laboratory

    directors”, 25 sites (200-300 individuals) participating from across the U.S. and Canada, 4/25/2017.

    Brazauskas R. “Statistical Concepts Encountered in Medical Literature on HCT. CIBMTR Training Day. 90

    participants”, 06/21/2017.

    Brazauskas R, Logan B, Frazer R. “Phase II Trials and the Use of Registry Controls. Joint Statistical Meetings.”

    Baltimore, MD, 08/2017.

    Kim S, "Competing risks regression for case-cohort studies," MCW Biostatistics conference, Milwaukee, WI,

    September 2017.

    Logan BR, Brazauskas R, Fraser R. “Randomized phase II trials vs. single arm phase II trials with a registry control in

    rare diseases," (International Chinese Statistical Association Meeting (06/2017).

    Sparapani R., Rein L, Tarima S, Jackson T and Meurer J, “Nonparametric Recurrent Events Analysis with BART and

    an Application to the Hospital Admissions of Patients with Diabetes, Lifetime Data Science Conference”,

    Storrs, CT, 05/25/2017 - 05/27/2017.

    Sparapani, R, Rein L, Tarima S, Jackson T and Meurer J, “Nonparametric recurrent events analysis with BART and an

    application to hospital admissions for patients with diabetes," Kliakhandler Conference, Houghton, MI,

    08/16/2017 - 08/20/2017.

    2018

    Szabo A, DeVogel N, "Partial observability with exchangeable binary outcomes," 8/2/2017, Joint Statistical Meetings,

    Baltimore.

    Brazauskas R. and Le-Rademacher J, “Joint 2018 IMS Annual Meeting/12th International Vilnius Conference on

    Probability Theory & Mathematical Statistics, Presenting Survival Data when Group Assignment is Time-

    Dependent”, Vilnius, Lithuania, July 2018.

    Hyun N, “Risk prediction models for left-/interval-censored data from electronic health records," Department of

    Mathematics and Statistics, University of Nevada, Reno, April 2018.

    Hyun N, “Sample-Weighted Semiparametric Estimates of Cause-Specific Cumulative Incidence Using Left-/Interval

    Censored Data from Electronic Health Records," Joint Statistical Meetings, Vancouver, Canada, Aug 2018.

    Kim S, Xu Y, Zhang MJ, Ahn KW, “Competing Risks Regression for Case-Cohort Design," ENAR spring meetings,

    Philadelphia, PA., March 2018.

    Lin CW, “International Chinese Statistical Association (ICSA) Symposium., RNASeqDesign: A framework for RNA-

    Seq genome-wide power calculation and experimental design issues," New Brunswick, NJ, June 2018.

  • Page 20 of 36

    Lin CW, “International Chinese Statistical Association (ICSA) China Conference, RNASeqDesign: A framework for

    RNA-Seq genome-wide power calculation and experimental design issues," Qingdao, Shandong, China, July

    2018.

    Logan BR, “Individualized treatment for time-to-event outcomes with BART.” Joint Statistical Meetings, Vancouver,

    BC, CA, August 2018.

    Sahr N, Kim S, and Ahn KW, “Adaptive Group Bridge for Marginal Cox Proportional Hazards Models with multiple

    diseases," ENAR spring meetings, Atlanta, GA, March 2018.

    Tarima S, “Blinded and Unblinded Sample Size Recalculation for parametric models," Ninth Simulation Workshop.

    Barcelona, Spain, June 2018

    APPENDIX 1: PRESENTATIONS

  • Page 21 of 36

    APPENDIX 2: COLLABORATIVE PAPERS & PUBLICATIONS

    2017

    Abu Zaid M., et al. (2017). "Plasma biomarkers of risk for death in a multicenter phase 3 trial with uniform transplant

    characteristics post-allogeneic HCT." Blood 129(2): 162-170.

    Askar M, et al. (2017). "MHC Class I Chain-Related Gene A (MICA) Donor-Recipient Mismatches and MICA-129

    Polymorphism in Unrelated Donor Hematopoietic Cell Transplantations Has No Impact on Outcomes in Acute

    Lymphoblastic Leukemia, Acute Myeloid Leukemia, or Myelodysplastic Syndrome: A Center for International

    Blood and Marrow Transplant Research Study." Biology of Blood and Marrow Transplantation 23(3): 436-444.

    Azam LS, Jackson TA, Knudson PE, Meurer JR and Tarima S. (2017). “Research in social & administrative pharmacy”

    Res Social Adm Pharm 13 494–502.

    Bashey A, et al. (2017). "Mobilized Peripheral Blood Stem Cells Versus Unstimulated Bone Marrow as a Graft Source

    for T-Cell–Replete Haploidentical Donor Transplantation Using Post-Transplant Cyclophosphamide." Journal

    of Clinical Oncology 35(26): 3002-3009.

    Bejanyan N, et al. (2017). "Pretransplant Consolidation Is Not Beneficial for Adults with ALL Undergoing

    Myeloablative Allogeneic Transplantation." Biology of Blood and Marrow Transplantation.

    Bhagavatula P, Xiang Q, Szabo A, Eichmiller F and Okunseri C. (2017). “Differences in utilization of dental procedures

    by children enrolled in Wisconsin Medicaid and Delta Dental insurance plans” J Public Health Dent 77 86–92.

    Bitan, M, et al. (2017). "Personalized Prognostic Risk Score for Long-Term Survival for Children with Acute Leukemia

    after Allogeneic Transplantation." Biology of Blood and Marrow Transplantation 23(9): 1523-1530.

    Brunstein C, et al. (2017). "The effect of inter-unit HLA matching in double umbilical cord blood transplantation for

    acute leukemia." Haematologica 102(5): 941-947.

    Casulo C, et al. (2017). "Autologous Transplantation in Follicular Lymphoma with Early Therapy Failure: A National

    LymphoCare Study and Center for International Blood and Marrow Transplant Research Analysis." Biology of

    Blood and Marrow Transplantation.

    Chen YB, Wang T, Hemmer MT, Brady C. (2017). “GvHD after umbilical cord blood transplantation for acute

    leukemia: an analysis of risk factors and effect on outcomes” Bone Marrow Transplant 52 400–8.

    Cheng YC, Shi Y, Zhang MJ, Brazauskas R, Hemmer MT. (2017). “Long-Term Outcome of Inflammatory Breast

    Cancer Compared to Non-Inflammatory Breast Cancer in the Setting of High-Dose Chemotherapy with

    Autologous Hematopoietic” Cell Transplantation J Cancer 8 1009–17.

    Cheung LC, et al. (2017). "Mixture models for undiagnosed prevalent disease and interval‐censored incident

    disease: applications to a cohort assembled from electronic health records." Statistics in Medicine 36(22):

    3583-3595.

    Chimukangara M, Helm M C, Frelich MJ, Bosler ME, Rein L, Szabo A and Gould JC. (2017). “A 5-item frailty

    index based on NSQIP data correlates with outcomes following paraoesophageal hernia repair” Surg

    Endosc 31 2509–19.

    Cornell R.F, et al. (2017). "Allogeneic Transplantation for Relapsed Waldenström Macroglobulinemia and

    Lymphoplasmacytic Lymphoma." Biology of Blood and Marrow Transplantation 23(1): 60-66.

  • Page 22 of 36

    Cornell, RF, et al. (2017). "Maintenance versus Induction Therapy Choice on Outcomes after Autologous

    Transplantation for Multiple Myeloma." Biology of Blood and Marrow Transplantation 23(2): 269-277.

    Dhakal, B, et al. (2017). "Local Disease Control in Ocular Adnexal Lymphoproliferative Disorders: Comparative

    Outcomes of MALT Versus Non-MALT Histologies." Clinical Lymphoma Myeloma and Leukemia.

    Dhakal B, et al. (2017). "Autologous Hematopoietic Cell Transplantation in Patients with Multiple Myeloma:

    Effect of Age." Clinical Lymphoma Myeloma and Leukemia 17(3): 165-172.

    Diniz BS, Reynolds CF, Sibille E, Lin CW. (2017). “Enhanced Molecular Aging in Late-Life Depression: The

    Senescent-Associated Secretory Phenotype” Am J Geriatr Psychiatry 25 64–72.

    Doering JJ, Szabo A, Goyal D and Babler E. (2017). “Sleep Quality and Quantity in Low-Income” Postpartum

    Women Journal of Maternal Child Nursing 42 166–72.

    D'Souza, A, et al. (2017). "Trends in pre- and post-transplant therapies with first autologous hematopoietic cell

    transplantation among patients with multiple myeloma in the United States, 2004–2014." Leukemia 31:

    1998.

    Eapen M, et al. (2017). "Umbilical Cord Blood Transplantation in Children with Acute Leukemia: Impact of

    Conditioning on Transplantation Outcomes." Biology of Blood and Marrow Transplantation 23(10):

    1714-1721.

    Eapen M, et al. (2017). "Allele-level HLA matching for umbilical cord blood transplantation for non-malignant

    diseases in children: a retrospective analysis." The Lancet Hematology 4(7): e325-e333.

    El-Jawahri A, et al. (2017). "Impact of pre-transplant depression on outcomes of allogeneic and autologous

    hematopoietic stem cell transplantation." Cancer.

    Epperla N, et al. (2017). "Predictive factors and outcomes for ibrutinib therapy in relapsed/refractory mantle cell

    lymphoma—a “real world” study." Hematological oncology.

    Ertl AM, Beyer KM, Tarima S, Zhou Y, Groner JI and Cassidy LD. (2017). “The spatial epidemiology of pediatric

    trauma: A statewide assessment J Trauma” Acute Care Surg 83 225–9.

    Esteban, JP, et al. (2017). "Tu1516-Comparative Perspectives of Liver and Palliative Care Clinicians on Palliative Care

    Services in End-Stage Liver Disease." Gastroenterology 152(5): S1192.

    Fleischhauer K, et al. (2017). "Directionality of non-permissive HLA-DPB1 T-cell epitope group mismatches do not

    improve clinical risk stratification in 8/8 matched unrelated donor hematopoietic cell transplantation." Bone

    marrow transplantation 52: 1280.

    Fritz JM, Inawat RR, Slavens BA, McGuire J R, Ziegler DW, Tarima S. (2017). “Assessment of Kinematics and

    Electromyography Following Arthroscopic Single-Tendon Rotator Cuff Repair” PM R 9 464–76

    Gadalla SM, Wang T, Loftus D, Friedman L, Dagnall C. (2017). "No association between donor telomere length and

    outcomes after allogeneic unrelated hematopoietic cell transplant in patients with acute leukemia Bone Marrow

    Transplant."

    Garcia D, et al. (2017). "Latino Acculturation and Periodontitis Status Among Mexican-Origin Adults in the United

    States: NHANES 2009-2012." Family & community health 40(2): 112-120.

    Gerds AT, et al. (2017). "Outcomes after Umbilical Cord Blood Transplantation for Myelodysplastic Syndromes."

    Biology of Blood and Marrow Transplantation 23(6): 971-979.

    APPENDIX 2: COLLABORATIVE PAPERS & PUBLICATIONS

  • Page 23 of 36

    Goyal RK, Lee SJ, Wang T, Trucco M, Haagenson M, Spellman SR. (2017). “Novel HLA-DP region susceptibility loci

    associated with severe acute GvHD Bone Marrow Transplant” 52 95–100.

    Hamadani M, et al. (2017). "Allogeneic Hematopoietic Cell Transplantation for Aggressive NK Cell Leukemia. A

    Center for International Blood and Marrow Transplant Research Analysis." Biology of Blood and Marrow

    Transplantation 23(5): 853-856.

    Heimall J, et al. (2017). "Immune reconstitution and survival of 100 SCID patients post–hematopoietic cell transplant: a

    PIDTC natural history study." Blood 130(25): 2718-2727.

    Hoff, GA, et al. (2017). "Recipient HLA-C Haplotypes and microRNA 148a/b Binding Sites Have No Impact on

    Allogeneic Hematopoietic Cell Transplantation Outcomes." Biology of Blood and Marrow Transplantation

    23(1): 153-160.

    Holmes B, Brazauskas R, Cassidy L, Wiegand R. (2017). “Factors in Patient Responsiveness to Directional Preference-

    Matched Treatment of Neck Pain with or Without Upper Extremity” Radiation Journal of Patient-Centered

    Research and Reviews 4 60–8.

    Inoue YY, Soliman EZ, Yoneyama K, Ambale-Venkatesh B, Wu CO, Sparapani R. (2017). “Electrocardiographic

    Strain Pattern Is Associated with Left Ventricular Concentric Remodeling, Scar, and Mortality Over 10 Years:

    The Multi-Ethnic Study of Atherosclerosis J Am Heart Assoc 6”.

    Kaczmarowski AL, et al. (2017). "Predictive Cytological Topography (PiCT): a Radiopathomics Approach to Mapping

    Prostate Cancer." Clin.Cancer Res.

    Kanate AS, et al. (2017). "Recipient Immune Modulation with Atorvastatin for Acute Graft-versus-Host Disease

    Prophylaxis after Allogeneic Transplantation." Biology of Blood and Marrow Transplantation 23(8): 1295-

    1302.

    Kekre N, et al. (2017). "Effect of antithymocyte globulin source on outcomes of bone marrow transplantation for severe

    aplastic anemia." Haematologica 102(7): 1291-1298.

    Khoury H.J, et al. (2017). "Improved survival after acute graft-versus-host disease diagnosis in the modern

    era." Haematologica 102(5): 958-966.

    Koehler SM, Szabo A, Loichinger M, Peterson E. (2017). “The significance of organ prolapses in gastroschisis J-

    Pediatr-Surg” 52 1972–6.

    Krakow EF, Hemmer M, Wang T, Logan BR, Arora M. (2017). “Tools for the Precision Medicine Era: How to Develop

    Highly Personalized Treatment Recommendations from Cohort and Registry Data Using Q-Learning Am-J-

    Epidemiol” 186 160–72.

    Kumar SK, et al. (2017). "Early relapse after autologous hematopoietic cell transplantation remains a poor prognostic

    factor in multiple myeloma but outcomes have improved over time." Leukemia 32: 986.

    Lampe JW, et al. (2017). "Dietary biomarker evaluation in a controlled feeding study in women from the Women's

    Health Initiative cohort." The American Journal of Clinical Nutrition 105(2): 466-475.

    Landy R, Cheung LC, Schiffman M, Gage JC, Hyun N. (2017). "Challenges in risk estimation using routinely collected

    clinical data: The example of estimating cervical cancer risks from electronic health-records Prev Med."

    Levin A, et al. (2017). "Early mortality in patients with acute myelogenous leukemia treated in teaching versus non‐teaching hospitals: A large database analysis." American Journal of Hematology 92(9): E563-E565.

    APPENDIX 2: COLLABORATIVE PAPERS & PUBLICATIONS

  • Page 24 of 36

    Lindsley, RC, et al. (2017). "Prognostic mutations in myelodysplastic syndrome after stem-cell transplantation." New

    England Journal of Medicine 376(6): 536-547.

    Liu HD, et al. (2017). "Allogeneic Hematopoietic Cell Transplantation for Adult Chronic Myelomonocytic Leukemia."

    Biology of Blood and Marrow Transplantation 23(5): 767-775.

    Madbouly A, et al. (2017). "Investigating the Association of Genetic Admixture and Donor/Recipient Genetic Disparity

    with Transplant Outcomes." Biology of Blood and Marrow Transplantation 23(6): 1029-1037.

    Magenau J, et al. (2017). "A multicenter trial of myeloablative clofarabine and busulfan conditioning for relapsed or

    primary induction failure AML not in remission at the time of allogeneic hematopoietic stem cell

    transplantation." Bone marrow transplantation 52(1): 59-65.

    Mahindra A, et al. (2017). "Autologous hematopoietic cell transplantation for multiple myeloma patients with renal

    insufficiency: a center for international blood and marrow transplant research analysis." Bone marrow

    transplantation 52: 1616.

    Mark S, et al. (2017). "Proof‐of‐principle study of a novel cervical screening and triage strategy: Computer‐analyzed

    cytology to decide which HPV‐positive women are likely to have ≥CIN2." International Journal of Cancer 140(3): 718-725.

    Matsushita K, Kwak L, Hyun N, Bessel M. (2017). “Community burden and prognostic impact of reduced kidney

    function among patients hospitalized with acute decompensated heart failure: The Atherosclerosis Risk in

    Communities (ARIC) Study Community Surveillance PLOS ONE 12 e0181373”.

    Maziarz RT, Brazauskas R, Chen M, McLeod A. (2017). “Pre-existing invasive fungal infection is not a

    contraindication for allogeneic HSCT for patients with hematologic malignancies: a CIBMTR study Bone

    Marrow Transplant” 52 270–8.

    Michelis FV, Gupta V, Zhang MJ, Wang HL, Aljurf M, Bacher U. (2017). “Cytogenetic risk determines outcomes after

    allogeneic transplantation in older patients with acute myeloid leukemia in their second complete remission: A

    Center for International Blood and Marrow Transplant Research cohort analysis Cancer 123 2035–42”.

    Miller JR, Zuperku EJ, Stuth EA E, Banerjee A. (2017). “A Subregion of the Parabrachial Nucleus Partially Mediates

    Respiratory Rate Depression from Intravenous Remifentanil in Young and Adult Rabbits Anesthesiology 127

    502–14”.

    Patel JJ, Kurman JS, Biesboer A, Taha H, Katz M, Szabo A. (2017). “Impact of duration of hypotension prior to

    norepinephrine initiation in medical intensive care unit patients with septic shock: A prospective observational

    study J Crit Care 40 178–83”.

    Ronen, S., et al. (2017). "PTEN loss and p27 loss differ among morphologic patterns of prostate cancer, including

    cribriform." Human Pathology 65: 85-91.

    Schriber, JR, Hari PN, Ahn, KW, et al. (2017). "Hispanics have the lowest stem cell transplant utilization rate for

    autologous hematopoietic cell transplantation for multiple myeloma in the United States: A CIBMTR report."

    Cancer 123(16): 3141-3149.

    Scott BL, et al. (2017). "Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute

    Myeloid Leukemia and Myelodysplastic Syndromes." Journal of clinical oncology: official journal of the

    American Society of Clinical Oncology 35(11): 1154-1161.

    Steinmetz CN, Zheng C, Okunseri E, Szabo A, Okunseri C. (2017). “Opioid Analgesic Prescribing Practices of Dental

    Professionals in the United States JDR Clin Trans Res 2 241–8”.

    APPENDIX 2: COLLABORATIVE PAPERS & PUBLICATIONS

  • Page 25 of 36

    Stolley M, et al. (2017). "Efficacy of a Weight Loss Intervention for African American Breast Cancer Survivors."

    Journal of Clinical Oncology 35(24): 2820-2828.

    Thompson J, et al. (2017). "Etanercept and Corticosteroid Therapy for the Treatment of Late-Onset Idiopathic

    Pneumonia Syndrome." Biology of Blood and Marrow Transplantation 23(11): 1955-1960.

    Ustun C, et al. (2017). "Outcomes of UCB transplantation are comparable in FLT3+ AML: results of CIBMTR,

    EUROCORD and EBMT collaborative analysis." Leukemia 31: 1408.

    V Michelis F, Gupta V, Zhang MJ, et al. (2017). "Cytogenetic risk determines outcomes after allogeneic transplantation

    in older patients with acute myeloid leukemia in their second complete remission: A Center for International

    Blood and Marrow Transplant Research cohort analysis." Cancer 123(11): 2035-2042.

    Vogel RN, Davis DB, Kimura BH, Rathinavelu S, Graves GS, Szabo A. (2017). “Neovascular Age-Related Macular

    Degeneration with Advanced Visual Loss Treated with Anti-Vascular Endothelial Growth Factor Therapy:

    Clinical Outcome and Prognostic Indicators Retina (Philadelphia, Pa”) 37 257–64.

    Wang Y, et al. (2017). "Relative Telomere Length before Hematopoietic Cell Transplantation and Outcome after

    Unrelated Donor Hematopoietic Cell Transplantation for Acute Leukemia." Biology of Blood and Marrow

    Transplantation 23(7): 1054-1058.

    Weisdorf DJ, et al. (2017). "Allogeneic transplantation for advanced acute myeloid leukemia: The value of complete

    remission." Cancer.

    Wingard, JR, et al. (2017). "Pretransplantation Exercise and Hematopoietic Cell Transplantation Survival: A Secondary

    Analysis of Blood and Marrow Transplant Clinical Trials Network (BMT CTN 0902)." Biology of blood and

    marrow transplantation: journal of the American Society for Blood and Marrow Transplantation 23(1): 161-164.

    Weston BW, Jasti J, Lerner EB, Szabo A, Aufderheide TP, Colella MR. (2017). "Does an individualized feedback

    mechanism improve quality of out-of-hospital CPR? Resuscitation 113 96–100."

    Yen TW, et al. (2017). "Effect of hospital volume on processes of breast cancer care: A National Cancer Data Base

    study." Cancer 123(6): 957-966.

    2018

    Addesso LC, Nimmer M, Visotcky A, Fraser R, Brousseau D. (2018). "Impact of Medical Scribes on Provider

    Efficiency in the Pediatric Emergency Department." Academic Emergency Medicine 0(0).

    Ahn KW, Banerjee A, Sahr N, Kim S. (2018). "Group and within-group variable selection for competing risks

    data." Lifetime Data Analysis 24(3): 407-424.

    Ahn KW, Kim S. (2018). "Variable selection with group structure in competing risks quantile regression."

    Statistics in Medicine 37(9): 1577-1586.

    Ahn KW, Sahr N, Kim S. (2018). "Screening group variables in the proportional hazards model." Statistics &

    Probability Letters 135: 20-25.

    Alousi A, Wang T, Hemmer MT, Spellman SR, Arora M, et al. (2018). "Peripheral Blood versus Bone Marrow

    from Unrelated Donors: Bone Marrow Allografts Have Improved Long-Term Overall and Graft-versus-

    Host Disease-Free, Relapse-Free Survival." Biology of Blood and Marrow Transplantation 25(2): 270-

    278.

    APPENDIX 2: COLLABORATIVE PAPERS & PUBLICATIONS

  • Page 26 of 36

    Amin R, Knezevich M, Lingongo M, Szabo A, Yin Z, Oldham, et al. (2018). Long-term Quality of Life in

    Neonatal Surgical Disease. Annals of Surgery, 268(3), 497–505.

    Amirkhanian Y, Kelly J, DiFranceisco W, Kuznetsova A, Tarima S, Yakovlev A, Musatov V. (2018). "Predictors

    of HIV Care Engagement, Antiretroviral Medication Adherence, and Viral Suppression Among People

    Living with HIV Infection in St. Petersburg, Russia." AIDS and Behavior 22(3): 791-799.

    Banerjee A, DeVogel A, Pintar FA, Yoganandan N, et al. (2018). "Novel learning framework (knockoff

    technique) to evaluate metric ranking algorithms to describe human response to injury AU - Banerjee,

    Anjishnu." Traffic injury prevention: 1-6.

    Arrieta-Bolaños E, Crivello P, Shaw BE, Ahn KW, et al. (2018). "In silico prediction of nonpermissive HLA-

    DPB1 mismatches in unrelated HCT by functional distance." Blood Advances 2(14): 1773-1783.

    Askar M, Sayer D, Wang T, Haagenson M, Spellman SR, Lee SJ, Madbouly A, et al. (2018). "Analysis of Single

    Nucleotide Polymorphisms in the Gamma Block of the Major Histocompatibility Complex in Association

    with Clinical Outcomes of Hematopoietic Cell Transplantation: A Center for International Blood and

    Marrow Transplant Research Study." Biology of Blood and Marrow Transplantation.

    Atallah E, Schiffer CA, Weinfurt KP, Zhang MJ, Radich JP, Oehler, et al. (2018). "Design and rationale for the

    life after stopping tyrosine kinase inhibitors (LAST) study, a prospective, single-group longitudinal study

    in patients with chronic myeloid leukemia." BMC Cancer 18(1): 359.

    Babaei A, Szabo A, Yorio SD, Massey BT. (2018). "Pressure exposure and catheter impingement affect the

    recorded pressure in the Manoscan 360™ system." Neurogastroenterology & Motility 30(8): e13329.

    Bachanova V, Weisdorf DJ, Wang T, Marsh SGE, Cereb N, Haagenson MD, Spellman SR, et al. (2018). "Donor

    Killer Cell Immunoglobulin-Like Receptor Genotype Does Not Improve Graft-versus-Leukemia

    Responses in Chronic Lymphocytic Leukemia after Unrelated Donor Transplant: A Center for

    International Blood and Marrow Transplant Research Analysis." Biology of Blood and Marrow

    Transplantation.

    Bagheri A, Liu XC, Tassone C, Thometz J, Tarima S. (2018). "Reliability of Three-Dimensional Spinal Modeling

    of Patients with Idiopathic Scoliosis Using EOS System." Spine Deformity 6(3): 207-212.

    Bejanyan N, Zhang MJ, Wang HL, Lazaryan A, de Lima M, Marks DI, Sandmaier BM. (2018). "Pretransplant

    Consolidation Is Not Beneficial for Adults with ALL Undergoing Myeloablative Allogeneic

    Transplantation." Biology of Blood and Marrow Transplantation 24(5): 945-955.

    Beyer KMM, Szabo A, Hoormann K, Stolley M. (2018). "Time spent outdoors, activity levels, and chronic

    disease among American adults." Journal of Behavioral Medicine 41(4): 494-503.

    Bhatt NS, Brazauskas R, Tecca HR, Carreras J, Burns LJ, Phelan R, et al. (2018). "Post-transplantation

    employment status of adult survivors of childhood allogeneic hematopoietic cell transplant: A report from

    the Center for International Blood and Marrow Transplant Research (CIBMTR)." Cancer 125(1): 144-

    152.

    Bhatt NS, Brazauskas R, Tecca HR, Vogel J, Mattila D, Lee SJ, et al. (2018). "Female Sex is Associated with

    Poor Health-related Quality of Life in Children at 12 Months Post-Hematopoietic Cell Transplantation."

    Journal of Pediatric Hematology/Oncology Publish Ahead of Print.

    Borchardt LN, Pickett ML, Tan KT, Visotcky AM, Drendel AL. (2018). Expedited Partner Therapy. Sexually

    Transmitted Diseases, 45(5), 350–353.

  • Page 27 of 36

    Borkenhagen JF, Eastwood D, See WA, Wickle D, Lawton, CA, et al. (2018) "Digital Rectal Exam Remains a

    Key Prognostic Tool for Prostate Cancer Patients: A National Cancer Database Review." In press.

    Buturovic L, Shelton J, Spellman SR, Wang T, Friedman L, Loftus D, et al. (2018). "Evaluation of a Machine

    Learning-Based Prognostic Model for Unrelated Hematopoietic Cell Transplantation Donor Selection."

    Biology of Blood and Marrow Transplantation.

    Cabrera SM, Engle S, Kaldunski M, Jia S, Geoffrey R, Simpson P, Szabo A, et al. (2018). "Innate immune

    activity as a predictor of persistent insulin secretion and association with responsiveness to CTLA4-Ig

    treatment in recent-onset type 1 diabetes." Diabetologia 61(11): 2356-2370.

    Canseco K, Kruger K, Fritz J, Konop K, Tarima S, et al. (2018). "Distribution of segmental foot kinematics in

    patients with degenerative joint disease of the ankle." Journal of Orthopedic Research 36(6): 1739-1746.

    Carpenter PA, Logan BR, Lee SJ, Weisdorf DJ, Johnston L, Costa LJ, et al. (2018). "A phase II/III randomized,

    multicenter trial of prednisone/sirolimus versus prednisone/sirolimus/calcineurin inhibitor for the

    treatment of chronic graft-versus-host disease: BMT CTN 0801." Haematologica 103(11): 1915-1924.

    Carver TW, Kugler NW, Juul J, Peppard WJ, Drescher KM, Somberg LB, Szabo A, et al. (2018). "Ketamine

    infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control

    trial." Journal of Trauma and Acute Care Surgery 86(2): 181-188. In press.

    Casulo C, Friedberg JW, Ahn KW, et al. (2018). "Autologous Transplantation in Follicular Lymphoma with Early

    Therapy Failure: A National LymphoCare Study and Center for International Blood and Marrow

    Transplant Research Analysis." Biology of Blood and Marrow Transplantation 24(6): 1163-1171.

    Chaudhary LN, Jawa Z, Hanif A, Szabo A et al. (2018). "Does Progesterone Receptor Matter in the Risk of

    Recurrence for Patients with Ductal Carcinoma in Situ?" Wisconsin Medical Journal 117(2): 62.

    Chhabra S, Ahn KW, Hu ZH, Jain S, et al. (2018). "Myeloablative vs reduced-intensity conditioning allogeneic

    hematopoietic cell transplantation for chronic myeloid leukemia." Blood Advances 2(21): 2922-2936.

    Chhabra S, Liu Y, Hemmer M, Costa L, et al. (2018). "Comparative Analysis of Calcineurin Inhibitor-Based

    Methotrexate and Mycophenolate Mofetil–Containing Regimens for Prevention of Graft-versus-Host

    Disease after Reduced-Intensity Conditioning Allogeneic Transplantation." Biology of Blood and Marrow

    Transplantation 25(1): 73-85.

    Chirvi S, Pintar F, Yoganandan N, Banerjee A, Schlick M, et al. (2018). "Human Foot-Ankle Injuries and

    Associated Risk Curves from Under Body Blast Loading Conditions." Stapp Car Crash J 2017 Nov;

    61:157-173

    Chowdhury TA, Koceja C, Eisa-Beygi S, Kleinstiver BP, Kumar SN, Lin CW, Li K, Prabhudesai S. (2018).

    "Temporal and Spatial Post-Transcriptional Regulation of Zebrafish tie1 mRNA by Long Noncoding

    RNA During Brain Vascular Assembly." Arteriosclerosis, Thrombosis, and Vascular Biology 38(7):

    1562-1575.

    Colwell EM, Encarnacion CO, Rein LE, Szabo A, Haasler G, Gasparri M, et al. (2018). "Atrial fibrillation after

    transhiatal esophagectomy with transcervical endoscopic esophageal mobilization: one institution’s

    experience." Journal of Cardiothoracic Surgery 13(1): 73.

    Demarco M, Carter-Pokras O, Hyun N, Castle PE, He X. (2018). "Validation of a Human Papillomavirus (HPV)

    DNA Cervical Screening Test That Provides Expanded HPV Typing." Journal of Clinical Microbiology

    56(5).

  • Page 28 of 36

    Dhakal B, Kreuziger L B, Rein, L, Kleman A, Fraser R, Aster RH, Hari P. Padmanabhan A. (2018). "Disease

    burden, complication rates, and health-care costs of heparin-induced thrombocytopenia in the USA: a

    population-based study." The Lancet Haematology 5(5): e220-e231.

    Dhakal B, Szabo A, Chhabra S, Hamadani M, D'Souza A, Usmani SZ, Sieracki R, et al. (2018). "Autologous

    transplantation for newly diagnosed multiple myeloma in the era of novel agent induction: A systematic

    review and meta-analysis." JAMA oncology 4(3): 343-350.

    Dhakal B, Szabo A, Hari P. (2018). "Meta-analysis to evaluate high-dose therapy followed by stem cell transplant

    in patients with multiple myeloma—reply." JAMA oncology 4(11): 1618-1618.

    Donglin Zeng, Noorie Hyun, Jianwen Cai. (2018). "Semiparametric additive model for estimating risk difference

    in multicenter studies AU - Zeng, Donglin." Biostatistics & Epidemiology 2(1): 84-98.

    Dreger P, Sureda A, Ahn KW, Eapen M, et al. (2018). "Post-transplant cyclophosphamide (PT-Cy) based

    haploidentical transplantation (haploHCT) versus matched sibling (MSD) or matched unrelated donor

    (MUD) reduced intensity conditioning (RIC) HCT for diffuse large b-cell lymphoma (DLBCL): A

    CIBMTR and EBMT analysis." Journal of Clinical Oncology 36(15_suppl): 7056-7056.

    Drobyski WR, Szabo A, Zhu F, Keever-Taylor C, Hebert KM, Dunn, et al. (2018). "Tocilizumab, tacrolimus and

    methotrexate for the prevention of acute graft versus host disease: low incidence of lower gastrointestinal

    tract disease." Haematologica: haematol.2017.183434.

    D'Souza A, Millard H, Knight J, Brazauskas R, Lee SJ, Flynn KE, Rizzo JD, Shaw BE. (2018). "Prevalence of

    self-reported sleep dysfunction before allogeneic hematopoietic cell transplantation." Bone marrow

    transplantation.

    Duncan CN, Brazauskas R, Huang J, Shaw BE, Majhail NS, Savani BN, et al. (2018). "Late cardiovascular

    morbidity and mortality following pediatric allogeneic hematopoietic cell transplantation." Bone marrow

    transplantation.

    Eapen M, Brazauskas R, Hemmer M, Perez WS, Steinert P, Horowitz MM, Deeg HJ (2018). "Hematopoietic cell

    transplant for acute myeloid leukemia and myelodysplastic syndrome: conditioning regimen intensity."

    Blood Advances 2(16): 2095-2103.

    Earl-Boehm JE, Bolgla LA, Emory C, Hamstra-Wright KL, Tarima S, Ferber R. (2018). "Treatment Success of

    Hip and Core or Knee Strengthening for Patellofemoral Pain: Development of Clinical Prediction Rules."

    Journal of athletic training 53(6): 545-552.

    Epperla N, Ahn KW, Armand P, Jaglowski S, Ahmed S, et al. (2018). "Fludarabine and Busulfan versus

    Fludarabine, Cyclophosphamide, and Rituximab as Reduced-Intensity Conditioning for Allogeneic

    Transplantation in Follicular Lymphoma." Biology of Blood and Marrow Transplantation 24(1): 78-85.

    Epperla N, Hamadani M, Ahn KW, et al. (2018). "Survival of Lymphoma Patients Experiencing Relapse or

    Progression after an Allogeneic Hematopoietic Cell Transplantation." Biology of Blood and Marrow

    Transplantation.

    Evans LC, Dayton A, Yang C, Liu P, Kurth T, Ahn KW, et al. (2018). "Transcriptomic analysis reveals

    inflammatory and metabolic pathways which are regulated by renal perfusion pressure in the outer

    medulla of Dahl-S rats." Physiological Genomics 0(0): null.

    Farooq, A, Jorda M, Whittington E, Kryvenko ON, Braunhut B, Pavan N, Procházková K, Zhang L, Rai S, Miller

    T, Liu, J, Szabo, A. (2018). "Rete Testis Invasion Is Consistent with Pathologic Stage T1 in Germ Cell

    Tumors." In press.

  • Page 29 of 36

    Gadalla SM, Aubert G, Wang T, Haagenson M, Spellman SR, Wang L, et al. (2018). "Donor Telomere Length

    and Causes of Death after Unrelated Hematopoietic Cell Transplant in Patients with Marrow Failure."

    Blood.

    Glisch, C, Jawa, Z A, Badar, T, Visotcky, A, Chaudhary, L, Chitambar, C, et al. (2018). "Androgen receptor

    expression in patients with triple negative breast cancer treated with neoadjuvant chemotherapy: A single

    institution experience." Journal of Clinical Oncology 36(15_suppl): e12662-e12662.

    Gopalakrishnan S., D'Souza A., Scott, E., Fraser R., Davila, O, Shah, N, et al. (2018). "Revised International

    Staging System Is Predictive and Prognostic for Early Relapse (

  • Page 30 of 36

    Jacobsohn DA, Loken MR, Fei M, Adams A, Brodersen LE, Logan BR, Ahn KW, Shaw BE, et al. (2018).

    "Outcomes of Measurable Residual Disease in Pediatric Acute Myeloid Leukemia before and after

    Hematopoietic Stem Cell Transplant: Validation of Difference from Normal Flow Cytometry with

    Chimerism Studies and Wilms Tumor 1 Gene Expression." Biology of Blood and Marrow

    Transplantation 24(10): 2040-2046.

    Kamaraju S, DeNomie M, Visotcky A, Banerjee A, Krause K, et al. (2018). "Increasing Mammography Uptake

    Through Academic-Community Partnerships Targeting Immigrant and Refugee Communities in

    Milwaukee." Wisconsin Medical Journal 117(2): 55-61.

    Kamaraju S, Olson J, DeNomie M, Visotcky A, Banerjee A, Asan O, et al. (2018). "Community Breast Health

    Education for Immigrants and Refugees: Lessons Learned in Outreach Efforts to Reduce Cancer

    Disparities." Journal of Cancer Education.

    Kamaraju S, Shi Y, Smith E, Nattinger AB, Laud P, Neuner J. (2018). "Are aromatase inhibitors associated with

    higher myocardial infarction risk in breast cancer patients? A Medicare population-based study." Clinical

    Cardiology 42(1): 93-100.

    Kanate AS, DiGilio A, Ahn KW, Malki MA, Jacobsen E, et al. (2018). "Allogeneic hematopoietic cell

    transplantation for extranodal natural killer/T-cell lymphoma, nasal type: a CIBMTR analysis." British

    journal of hematology 182(6): 916-920.

    Kapoor, R, Ayers, C, Visotcky, A, Mason, P, Kulinski, J. (2018). "Association of sex and height with a lower

    ankle brachial index in the general population." Vascular Medicine 23(6): 534-540.

    Kebriaei P, Anasetti C, Zhang MJ, Wang HL, Aldoss I, de Lima M. (2018). "Intravenous Busulfan Compared

    with Total Body Irradiation Pretransplant Conditioning for Adults with Acute Lymphoblastic Leukemia."

    Biology of Blood and Marrow Transplantation 24(4): 726-733.

    Keesler DA, St Martin A, Bonfim C, Seber A, Zhang MJ, Eapen M. (2018). "Bone Marrow versus Peripheral

    Blood from Unrelated Donors for Children and Adolescents with Acute Leukemia." Biology of Blood and

    Marrow Transplantation 24(12): 2487-2492.

    Kilari D, Hari P, Qayed M, Fraser R, Davila, O, Kumar S, et al. (2018). "Tandem high-dose chemotherapy and

    autologous hematopoietic stem cell transplantation (SCT) compared to single SCT for relapsed/refractory

    germ cell tumors (GCT)." Journal of Clinical Oncology 36(6_suppl): 572-572.

    Knight JM, Kerswill SA, Hari P, Cole SW, Logan BR, D'Souza A. (2018). "Repurposing existing medications as

    cancer therapy: design and feasibility of a randomized pilot investigating propranolol administration in

    patients receiving hematopoietic cell transplantation." BMC Cancer 18(1): 593.

    Koehler SM, Loichinger M, Peterson E, Christensen M, Szabo A, et al. (2018). "Meconium-stained amniotic fluid

    as a predictor of poor outcomes in gastroschisis." Journal of Pediatric Surgery 53(9): 1665-1668.

    Kruger KM, Garman CMR, Krzak JJ, Graf A, Hassani S, Tarima S, Sturm PF, et al. (2018). "Effects of Spinal

    Fusion for Idiopathic Scoliosis on Lower Body Kinematics During Gait*." Spine Deformity 6(4): 441-

    447.

    Kumar AJ, Kim S, Hemmer MT, Arora M, Spellman SR, Pidala JA, et al. (2018). "Graft-versus-host disease in

    recipients of male unrelated donor compared with parous female sibling donor transplants." Blood

    Advances 2(9): 1022-1031.

    Kumar, S.K., Dispenzieri, A., Fraser, R., Mingwei, F., Akpek, G., Cornell, R, et al. (2018). "Early relapse after

    autologous hematopoietic cell transplantation remains a poor prognostic factor in multiple myeloma but

    outcomes have improved over time." Leukemia 32: 986.

  • Page 31 of 36

    Landy R, Cheung LC, Schiffman M, Gage JC, Hyun N, Wentzensen N, Kinney WK, et al. (2018). "Challenges in

    risk estimation using routinely collected clinical data: The example of estimating cervical cancer risks

    from electronic health-records." Preventive Medicine 111: 429-435.

    Lee D, Woertz EN, Visotcky A, Wilk M, Heitkotter H, Tarima S. (2018). "The Henle Fiber Layer in Albinism:

    Comparison to Normal and Relationship to Outer Nuclear Layer Thickness and Foveal Cone Density the

    Henle Fiber Layer in Albinism." Investigative ophthalmology & visual science 59(13): 5336-5348.

    Lerner EB, Studnek JR, Fumo N, Banerjee A, Arapi I, Browne LR, et al. (2018). "Multicenter Analysis of

    Transport Destinations for Pediatric Prehospital Patients." Academic Emergency Medicine 0(0).

    Levas MN, Melzer-Lange M, Tarima S, Beverung LM, Panepinto J. (2018). "Youth Victims of Violence Report

    Worse Quality of Life Than Youth with Chronic Diseases." Pediatric emergency care.

    Lin CW, Liao SG, Liu P, Lee, MLT, Park YS, Tseng GC. (2018) "RNASeqDesign: a framework for ribonucleic

    acid sequencing genomewide power calculation and study design issues." Journal of the Royal Statistical

    Society: Series C (Applied Statistics) 0(0).

    Linderman RE, Muthiah MN, Omoba SB, Litts K, Tarima S, Visotcky A, Kim JE, Carroll J. (2018). "Variability

    of Foveal Avascular Zone Metrics Derived from Optical Coherence Tomography Angiography Images."

    Translational Vision Science & Technology 7(5): 20-20.

    Liu C, Berger NG, Rein L, Tarima S, Clarke C, Mogal H, Christians KK, Tsai S, Gamblin TC. (2018).

    "Gallbladder carcinoma: An analysis of the national cancer database to examine Hispanic influence."

    Journal of surgical oncology 117(8): 1664-1671.

    Ma T, Huo Z, Kuo A, Zhu L, Fang Z, Zeng X, Lin CW, Liu S, Wang L, Liu P, et al. (2018). "MetaOmics:

    analysis pipeline and browser-based software suite for transcriptomic meta-analysis."

    Ma H, Gros E, Szabo A, Baginski SG, Laste, Z, et al. (2018). "Evaluation of motion artifact metrics for coronary

    CT angiography." Medical Physics 45(2): 687-702.

    Majhail NS, Murphy E, Laud P, Preussler JM, Denzen EM, Abetti B, Adams A, Besser R, et al. (2018).

    "Randomized controlled trial of individualized treatment summary and survivorship care plans for

    hematopoietic cell transplantation survivors." Haematologica: haematol.2018.203919.

    Mazotas I, Yen T, Park J, Liu Y, Eastwood D, et al. (2018). "A postoperative parathyroid hormone-based

    algorithm to reduce symptomatic hypocalcemia following completion/total thyroidectomy: A

    retrospective analysis of 591 patients." Surgery 164(4): 746-753.

    McCurdy SR, Zhang MJ, St Martin A, Al Malki MM, Bashey A, et al. (2018). "Effect of donor characteristics on

    haploidentical transplantation with posttransplantation cyclophosphamide." Blood Advances 2(3): 299-

    307.

    McGarry SD, Hurrell SL, Iczkowski KA, Hall W, Kaczmarowski AL, Banerjee A, et al. (2018). "Radio-Pathomic

    Maps of Epithelium and Lumen Density Predict the Location of High-Grade Prostate Cancer."

    International Journal of Radiation Oncology • Biology • Physics Aug 01;101(5):1179-1187.

    Miggelbrink AM, Logan BR, Buckley RH, Parrott RE, Dvorak CC, Kapoor N, et al. (2018). "B cell

    differentiation and IL-21 response in IL2RG/JAK3 SCID patients after hematopoietic stem cell

    transplantation." Blood: blood-2017-2010-809822.

    Mostafa ME, Abdelkader A, Kuroda N, Pérez-Montiel D, Banerjee A, et al. (2018). "Variation in nuclear size and

    PD-L2 positivity correlate with aggressive chromophobe renal cell carcinoma." Annals of Diagnostic

    Pathology 34: 31-35.

  • Page 32 of 36

    Myers RM, Hill BT, Shaw BE, Kim S, et al. (2018). "Long-term outcomes among 2-year survivors of autologous

    hematopoietic cell transplantation for Hodgkin and diffuse large b-cell lymphoma." Cancer 124(4): 816-

    825.

    Nelson, L, Furger, R, Ranson, J, Tarima, S, Hammeke, T, Randolph, C, et al. (2018). "Acute Clinical Predictors

    of Symptom Recovery in Emergency Department Patients with Uncomplicated Mild Traumatic Brain

    Injury or Non-Traumatic Brain Injuries." Journal of Neurotrauma 35(2): 249-259.

    Neuner JM, Shi Y, Kong AL, Kamaraju S, Smith EC, Laud PW, et al. (2018). "Fractures in a nationwide

    population-based cohort of users of breast cancer hormonal therapy." Journal of Cancer Survivorship

    12(2): 268-275

    Nikiforow S, Wang T, Hemmer M, Spellman S, Akpek G, Antin JH, et al. (2018). "Upper gastrointestinal acute

    graft-versus-host disease adds minimal prognostic value in isolation or with other graft-versus-host

    disease symptoms as currently diagnosed and treated." Haematologica 103(10): 1708-1719.

    Norkin M, Shaw BE, Brazauskas R, Tecca HR, Leather HL, Gea-Banacloche J, T Kamble R, et al. (2018).

    "Characteristics of Late Fatal Infections after Allogeneic Hematopoietic Cell Transplantation." Biology of

    Blood and Marrow Transplantation 25(2): 362-368.

    Okunseri C, Okunseri E, Garcia R, Gonzalez C, Visotcky A, Szabo A. (2018). "Impact of Wisconsin Medicaid

    Policy Change on Dental Sealant Utilization." Health services research 53(1): 312-325.

    Owczarzak J, Broaddus M, Tarima S. (2018). "Effectiveness of an evidence-based HIV prevention intervention

    when implemented by frontline providers." Translational Behavioral Medicine 8(6): 917-926.

    Papanicolaou GA, Ustun C, Young JAH, Chen M, Kim S, Ahn KW, et al. (2018). "Bloodstream infection (BSI)

    due to Vancomycin-Resistant Enterococcus (VRE) is associated with increased mortality after

    hematopoietic cell transplantation for acute leukemia and myelodysplastic syndrome: A multicenter,

    retrospective cohort study."

    Patel J, Kurman J, Al-Ghandour E, Thandra K, Graf J, Rein L, et al. (2018). "Predictors of 24-h mortality after

    inter-hospital transfer to a tertiary medical intensive care unit." Journal of the Intensive Care Society

    19(4): 319-325.

    Patel G, Parameswaran, H; Szabo A, Rein L, Kreuziger L, Baumann, L, et al. (2018). "Acquired factor X

    deficiency in light-chain (AL) amyloidosis is rare and associated with advanced disease."

    Hematology/oncology and stem cell therapy 12(1): 10-14.

    Perera, LP, Bhandari S, Liu R, Guilday C, Zadvornova Y, Saeian K, and Eastwood D. (2018). "Advanced Age

    Does Not Negatively Impact Health-Related Quality of Life in Inflammatory Bowel Disease." Digestive

    diseases and sciences, 63, 1787-1793.

    Petersdorf EW, Stevenson P, Malkki M, Strong RK, Spellman SR, Haagenson MD, Horowitz MM, Gooley T,

    Wang T, et al. (2018). "Patient HLA Germline Variation and Transplant Survivorship." Journal of

    Clinical Oncology 36(24): 2524-2531

    Pickett Mi, Melzer-Lange M, Miller M, Menon S, Visotcky A, Drendel A. (2018). "Perceived Patient Preference

    and Clinical Testing for Chlamydia and Gonorrhea in Females: How Closely Are These Aligned?"

    Clinical Pediatrics 57(1): 106-108.

    Pingel J, Wang T, Hagenlocher Y, Hernández-Frederick CJ, Nagler A, et al. (2018). "The effect of NIMA

    matching in adult unrelated mismatched hematopoietic stem cell transplantation – a joint study of the

    Acute Leukemia Working Party of the EBMT and the CIBMTR." Bone marrow transplantation.

  • Page 33 of 36

    Pulsipher MA, Logan BR, Chitphakdithai P, Kiefer DM, Riches ML, Rizzo JD, Anderlini P, Leitman SF, Varni

    JW, et al. (2018). "Effect of Aging and Predonation Comorbidities on the Related Peripheral Blood Stem

    Cell Donor Experience: Report from the Related Donor Safety Study." Biology of Blood and Marrow

    Transplantation.

    Pulsipher MA, Logan BR, Kiefer DM, Chitphakdithai P, Riches ML, Rizzo JD, Anderlini P, et al. (2018). "Higher

    Risks of Toxicity and Incomplete Recovery in 13- to 17-Year-Old Females after Marrow Donation:

    RDSafe Peds Results." Biology of Blood and Marrow Transplantation.

    Pulsipher MA, Logan BR, Kiefer DM, Chitphakdithai P, Riches ML, Rizzo JD, et al. (2018). "Related peripheral

    blood stem cell donors experience more severe symptoms and less complete recovery at 1-year compared

    to unrelated donors." Haematologica: haematol.2018.200121.

    Qayed M, Wang T, Hemmer MT, Spellman SR, Arora M, et al. (2018). "Influence of Age on Acute and Chronic

    GVHD in Children Undergoing HLA-Identical Sibling Bone Marrow Transplantation for Acute

    Leukemia: Implications for Prophylaxis." Biology of Blood and Marrow Transplantation 24(3): 521-528.

    Radivoyevitch T, Dean RM, Shaw BE, Brazauskas R, Tecca HR, Molenaar RJ, et al. (2018). "Risk of acute

    myeloid leukemia and myelodysplastic syndrome after autotransplants for lymphomas and plasma cell

    myeloma." Leukemia Research 74: 130-136.

    Raj RV, Hamadani M, Szabo A, Pasquini MC, Shah NN, Drobyski WR, Shaw, et al. (2018). "Peripheral Blood

    Grafts for T Cell–Replete Haploidentical Transplantation Increase the Incidence and Severity of Cytokine

    Release Syndrome." Biology of Blood and Marrow Transplantation 24(8): 1664-1670.

    Robinson TM, Fuchs EJ, Zhang MJ, St Martin A, Labopin M, Keesler DA, et al. (2018). "Related donor

    transplants: has posttransplantation cyclophosphamide nullified the detrimental effect of HLA

    mismatch?" Blood Advances 2(11): 1180-1186.

    Roddy JT, Arora VM, Chaudhry SI, Rein LM, Banerjee A, Swenson SL, Fletcher KE, et al. (2018). "The

    prevalence and implications of copy and paste: internal medicine program director perspectives." Journal

    of General Internal Medicine 33(12): 2032-2033.

    Rota K, Spanbauer C, Szabo A, Okunseri CE. (2018). "Oral Health Practices, Beliefs and Dental Service

    Utilization of Albanian Immigrants in Milwaukee, Wisconsin: A Pilot Study." Journal of Immigrant and

    Minority Health.

    Schmainda KM, Prah MA, Rand SD, Liu Y, Logan B, Muzi M, et al. (2018). "Multisite Concordance of DSC-

    MRI Analysis for Brain Tumors: Results of a National Cancer Institute Quantitative Imaging Network

    Collaborative Project." American Journal of Neuroradiology 39(6): 1008-1016.

    Schneidewend R, Hosking P, Brazauskas R, Peterson J, Beaudin C, Michaelis L, Atallah E, Hari P, Carlson K.

    (2018). "Early Fluorescence in situ Hybridization Assessment during Acute Myeloid Leukemia Induction

    Chemotherapy." Acta Haematologica 139(3): 171-175.

    Scott EC, Hari P, Kumar S, Fraser R, Davila O, et al. (2018). "Staging Systems for Newly Diagnosed Myeloma

    Patients Undergoing Autologous Hematopoietic Cell Transplantation: The Revised International Staging

    System Shows the Most Differentiation between Groups." Biology of Blood and Marrow Transplantation

    24(12): 2443-2449.

    Shah NN, Ahn KW, Litovich C, Fenske TS, et al. (2018). "Outcomes of Medicare-age eligible NHL patients

    receiving RIC allogeneic transplantation: a CIBMTR analysis." Blood Advances 2(8): 933-940.

  • Page 34 of 36

    Shah NN, Szabo A, Huntington SF, Epperla N, Reddy N, Ganguly S, et al. (2018). "R‐CHOP versus dose‐

    adjusted R‐EPOCH in frontline management of primary mediastinal B‐cell lymphoma: a multi‐centre analysis." British journal of hematology 180(4): 534-544.

    Shaw BE, Logan BR, Spellman SR, Marsh SGE, Robinson J, Pidala J, et al. (2018). "Development of an

    Unrelated Donor Selection Score Predictive of Survival after HCT: Donor Age Matters Most." Biology of

    Blood and Marrow Transplantation 24(5): 1049-1056.

    Shenkin JD, Warren J, Spanbauer C, Okunseri E, Szabo A (2018). "Hospital emergency department visits by

    ambulance for nontraumatic tooth pain in the USA." Clinical, cosmetic and investigational dentistry 10:

    159-163.

    Silva JP, Berger NG, Yin Z, Liu Y., Tsai S., Christians KK, Clarke CN, et al. (2018). "The effect of prior upper

    abdominal surgery on outcomes after liver transplantation for hepatocellular carcinoma: An analysis of

    the database of the organ procurement transplant network." Surgery 163(5): 1028-1034.

    Silva JP, Berger NG, Yin Z., Liu Y, Tsa, S, Christian K, et al. (2018). "Minimally invasive hepatectomy

    conversions: an analysis of risk factors and outcomes." HPB 20(2): 132-139.

    Singh S, Sparapani R, Wang MC, et al. (2018). "Variations in 30-day readmissions and length of stay among

    spine surgeons: a national s