AnnualReviewofResearch,inStemMarch6-8,2017

SundayMarch5,2017,6:45PM DinnerforSAB&InviteesDay1,MondayMarch6,2017

Time Speaker/event March6,20178:45-9:15 Registration,DasheriAuditorium,SouthernLaboratoriesComplex9:15-9:30 SatyajitMayor

Director,NCBS&inStemWelcome

Session:CellCommitment&DifferentiationChairpersonColinJamora,IFOM,inStem

9:30-10:00 ShravantiRampalliCITH

Euchromatichistonemethyltransferase1tethersheterochromatintothenuclearperiphery

10:00-10:30 DasaradhiPalakodetiTAS

DynamicexpressionoftRNA-derivedsmallRNAsdefinecellstates

10:30-11:00 SunilLaxmanRCF

Makingcommitments:howkeymetabolitesdeterminecellproliferationdecisions

11:00-11:30 BREAK

Chairperson:RamkumarSambasivam,inStem11:30-12:00 SrikalaRaghavan

CITH

RoleofMechanicalSignalinginMaintainingStemCellQuiescenceinMouseSkin

12:00-12:30 ApurvaSarinRCF

Notch1activityregulatessurvivalandlineageintegrityinT-regulatorycells

12:30–1:00 ManeeshaInamdarJNCASR

Bloodrelatives:TheroleofOCIAdomainproteinsinstemcellmaintenance

1:00-2:00 LUNCHforSAB&Invitees FirstFloormaincanteen

2:00-4:00

POSTERS

SLCColonnade

Chairperson:SrikalaRaghavan,inStem

4:00-4:30 TinaMukherjeeRCF

SystemicControlofMyeloidCellDifferentiationandCellularImmuneResponse

4:30-5:00 SiddharthanChandran,Univ.ofEdinburgh

Neuroprotectionthroughtargettingmacroglia?

5:15-7:00

POSTERSSLCColonnade

DiscussionMeetingsThemes

7:00 DinnerforSAB&Invitees Firstfloor,maincanteen

DAY2TuesdayMarch7,2017Time Speaker/eventMarch7,2017

Session:DiseaseMechanisms&RegenerationChairperson:ManeeshaInamdar,JNCASR

9:00-9:30 ColinJamoraCITH

Parsingthecontributionoffibroblastheterogeneitytotissuefibrosis

9:30-10:00 ArjunGuhaRCF

Airwayprogenitorsforalveolarrepair:Opportunitiesformany?

10:00-10:30 DhandapanyPerunduraiCCBD

Sarcomericdiseaseduetonon-sarcomericproteins

10:30-11:00 DavidWyllieUniversityofEdinburgh

C9ORF72repeatexpansioncausesvulnerabilityofmotorneuronstoCa2+-permeableAMPAreceptor-mediatedexcitotoxicity

11:00-11:30 BREAK

Chairperson:RaghuPadinjat,NCBS11:30-12:00 MahendraRao

CBDR

Largescalegenomicanalysisofpedigrees:Afirstyearperspective

12:00-12:30 ShonaChattarjiCBDR

Howdoesthesamereceptorintheamygdalagiverisetobothfearandanxiety?

12:30–1:00 RaviMuddashettyCBDR

FMRPandmiRISCmodulatesynapticproteinsynthesis

1:00-2:00 LUNCHforSAB&Invitees FirstFloormaincanteen2:00-4:00

POSTERS

SLCColonnade

Chairperson:ShonaChattarji,NCBS,CBDR,inStem

4:00-4:30 PeterKindUniversityofEdinburgh

DeconstructingthesynapticandcellularbasisofneuronalexcitabilityinarodentmodelofFragileXSyndrome

4:30-5:00 AshokVenkitaramanUniversityofCambridge

Earlyinterventionincancerthroughthetumoursuppressivemechanismsthatmaintaingenomestability

5:15-7:00

POSTERSSLCColonnade

DiscussionMeetingsThemes

7:00 DinnerforSAB&Invitees Firstfloor,maincanteen

DAY3Wednesday,March8,2017Time Speaker/event March8,2017

Session:EngineeringforDiscovery&TherapyChairperson:AratiRamesh,NCBS

9:00-9:30 JeffAbramsonUniversityofCalifornia,LosAngeles

DecipheringligandinducedconformationalchangesintheSodiumGalactoseTransporter(SGLT)

9:30-10:00 S.RamaswamyTAS

MolecularexplanationsofwhysomeWalleyesturnblue

10:00-10:30 AkashGulyaniTAS

Sensingacrossscales:FluorescentBiosensorsforcellulardynamicsanddiscoveriesinnaturallightsensing

10:30-11:00

KavithaBharatham&GayathriSadasivamCCBT

InterruptingintracellularsignalingviathemolecularrecognitionofphosphorylatedsubstratesbytheBRCTdomains

11:00-11:30 BREAK

Chairperson:SRamaswamy,inStem

11:30-12:00

MinhajSirajuddinCCBD

Nanoengineeringfordiscoveryanddiseasemechanismrelatedtocytoskeleton

12:00-12:30 PraveenVemulaTAS

Engineeringofbiomaterialsenables“disease-responsivedrugdelivery’forthetreatmentofinflammatoryboweldiseases

12:30–1:00 AlokSrivastavaCSCR,CMC-Vellore

GenetherapyforhemophiliaBinIndia

1:00-2:00 LUNCHforSAB&Invitees FirstFloormaincanteen2:00-5:005:00-5:30

POSTERS,SLCColonnadeHIGHTEA

SABMeetingFacultyLounge,SLC430-530:SABVisittotheNewBuilding

5:45-6:30 POSTERSAWARDSDasheriSLC

6:45

DinnerforSAB&Invitees

Firstfloor,maincanteen

MeetingCloses