8/8/2019 Angioleiomyoma. M 61, right 5th finger,

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AngioleiomyomaAngioleiomyoma

Deba P Sarma, MDDeba P Sarma, MD

OmahaOmaha

8/8/2019 Angioleiomyoma. M 61, right 5th finger,

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M 61, right 5M 61, right 5thth finger massfinger mass

8/8/2019 Angioleiomyoma. M 61, right 5th finger,

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8/8/2019 Angioleiomyoma. M 61, right 5th finger,

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8/8/2019 Angioleiomyoma. M 61, right 5th finger,

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SMA: Positive

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CommentComment

The encapsulated soft tissue tumor is composed ofThe encapsulated soft tissue tumor is composed of

numerous thicknumerous thick--walled and thinwalled and thin--walled vessels withwalled vessels with

perivascular pink spindle cell proliferation.perivascular pink spindle cell proliferation.

There is no increased mitosis, atypical mitosis orThere is no increased mitosis, atypical mitosis ornecrosis.necrosis.

The spindle cells are strongly positive for smoothThe spindle cells are strongly positive for smooth

muscle actin (SMA) suggesting leiomyomatousmuscle actin (SMA) suggesting leiomyomatous

nature of the tumor arising from the vessel wallsnature of the tumor arising from the vessel walls..

8/8/2019 Angioleiomyoma. M 61, right 5th finger,

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-- Solitary subcutaneous or dermal painful tumor ofSolitary subcutaneous or dermal painful tumor ofextremities and head.extremities and head.

-- More common in women.More common in women.

Pathologic findings:Pathologic findings:

-- Well circumscribed nodules composed of smooth muscle.Well circumscribed nodules composed of smooth muscle.

-- Smooth muscle cells of the tumor merges to the smoothSmooth muscle cells of the tumor merges to the smoothmuscle walls of vessels with with varying degree of patency.muscle walls of vessels with with varying degree of patency.

-- Smooth muscle markers are positive.Smooth muscle markers are positive.

-- Differential diagnosis: Dermatofibroma, neurofibroma,Differential diagnosis: Dermatofibroma, neurofibroma,

dermatomyofibromadermatomyofibroma