anaplastic lymphoma

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    Name of Drug General Action Specific Action Adverse Effect Indication Contraindication Nursin

    TRAMADOL 50mg

    1cap q8

    ANALGESIC,

    centrally acting

    Binds to mu-opoid

    receptors & inhibits thereuptake of

    norepinephrine &serotonin; causes many

    effects similar to theopoidsdizziness,

    somnolence, nausea,constipationbut does

    not have the respiratorydepressant effects.

    CNS: sedation,dizziness orvertigo,

    headache,confusion,

    dreaming,sweating,

    anxiety,seizures

    CV:hypotension,

    tachycardia,bradycardia

    DERMATOLOGIC:

    sweating,pruritus, rash,pallor, urticaria

    GI: nausea,vomiting, dry

    mouth,constipation,

    flatulence OTHER:potential forabuse,

    anaphtylactoidreactions,

    Relief of moderate to

    moderately severepain.

    Contraindicated with allergyto tramadol or

    opiods or acuteintoxication

    with alcohol,opiods or

    psychoactivedrugs.

    Use cautiouslyin pregnancy,

    lactation,seizures,

    concomitantdysfunction or

    hepaticimpairment.

    BEFORE

    Assessm

    y Hh

    ta

    a

    poa

    su

    dM

    hp

    o

    y Pt

    ob

    a

    Bnr

    DURING

    y C(

    se

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    W

    p

    pad

    AFTER:

    y Yt

    da

    ot

    na

    em

    y Rdc

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    Name of Drug General Action Specific Action Adverse Effect Indication Contraindication Nursin

    Prednisone 15mg/

    5ml 3-5ml TID aftermeals and afternoon

    snacks

    Corticosteroid Enters target cells and

    binds to intracellularcorticosteroid receptors,

    thereby initiating manycomplex reactions that

    are responsible for itsanti-inflammatory and

    immunosuppressiveeffects.

    yCNS: Vertigo,headache,

    paresthesias,insomnia, seizures,

    psychosis, cataracts,increased IOP,

    glaucoma (long-term

    therapy)yCV: Hypotension,shock, hypertensionand CHF secondary

    to fluid retention,thromboembolism,

    thrombophlebitis, fatembolism, cardiac

    arrhythmiasyElectrolyte

    imbalance:Na+ andfluid retention,

    hypokalemia,hypocalcemia

    yEndocrine: Growthretardation,decreased

    carbohydratetolerance, diabetes

    mellitus, cushingoidstate (long-term

    effect), increasedblood sugar,

    yReplacementtherapy in adrenal

    corticalinsufficiency

    yHypercalcemiaassociated withcancer

    yShort-termmanagement ofvariousinflammatory and

    allergic disorders,such as rheumatoid

    arthritis, collagendiseases (eg, SLE),

    dermatologicdiseases (eg,

    pemphigus), statusasthmaticus, and

    autoimmunedisorders

    yHematologicdisorders:thrombocytopenia

    purpura,erythroblastopenia

    yUlcerative colitis,acute exacerbationsof multiple sclerosis

    and palliation in

    yContraindicatedwithinfections,

    especiallytuberculosis, fungal

    infections,amebiasis, vaccinia

    and varicella, and

    antibiotic-resistantinfections; lactation.

    yUse cautiously withkidney or liver

    disease,hypothyroidism,

    ulcerative colitiswith impending

    perforation,diverticulitis, active

    or latent pepticulcer, inflammatory

    bowel disease,CHF, hypertension,

    thromboembolicdisorders,

    osteoporosis,seizure disorders,

    diabetes mellitus;hepatic disease;

    pregnancy (monitorinfants for adrenal

    insufficiency).

    yDo nowithou

    health

    yAvoidinfecti

    yReporswelli

    muscltarry s

    prolonor oth

    worsefor wh

    taken.

    yInstrudrug w

    yThe ordilutedflavor

    solid f

    yMonitpressu

    potassyWeigh

    report

    to pre

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    increased serum

    cholesterol,

    decreased T3 and T4levels, HPAsuppression with

    systemic therapylonger than 5 days

    yGI: Peptic oresophageal ulcer,pancreatitis,

    abdominaldistention, nausea,

    vomiting, increasedappetite, weight gain

    (long-term therapy)

    yHypersensitivity:Hypersensitivity or

    anaphylactoidreactions

    yMusculoskeletal:Muscle weakness,steroid myopathy,

    loss of muscle mass,osteoporosis,

    spontaneous

    fractures (long-termtherapy)

    yOther:Immunosuppression,

    aggravation ormasking of

    infections; impairedwound healing; thin,

    some leukemias and

    lymphomas

    yTrichinosis withneurologic ormyocardialinvolvement

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    fragile skin;

    petechiae,

    ecchymoses,purpura, striae;subcutaneous fat

    atrophy.

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    Name of Drug General Action Specific Action Adverse Effect Indication Contraindication Nursin

    Dolan Syrup

    (Ibuprofen)

    Analgesic

    NSAIDPropionic acid

    derivative

    Anti-inflammatory,

    analgesic and antipyreticactivities larely related to

    inhibition ofprostaglandin synthesis;

    exact mechanisms ofaction are not known.

    y CNS: headache,dizziness,

    somnolence,insomnia, fatigue,

    tiredness, tinnitus

    y CV: hypertension,palpitations,

    arrhythmia, heartfailure

    y GI: nausea,dyspepsia, GI pain,diarrhea, vomiting,

    constipation,flatulence, GI

    bleeding

    y GU: dysuria, renalimpairment,

    menorrhagia

    y HEMATOLOGIC:bleeding, platelet

    inhibition withhigher doses,

    neutropenia,eosinophilia,

    leukopenia,pancytopenia,

    thrombocytopenia

    y RESPIRATORY:dyspnea,

    hemoptysis,

    yRelief of s/s ofrheumatoid

    arthritis andosteoarthritis

    yRelief of mild tomoderate pain

    yTreatment ofprimarydysmenorrhea

    yFever reductionyUnlabeled uses:prophylactic for

    migraine; abortivetreatment for

    migraine

    y Contraindicatedwith allergy to

    ibuprofen,salicylates, or

    other NSAIDs

    y Contraindicatedfor treatment of

    perioperative painafter coronary

    artery bypass graft

    y Use cautiouslywith CV

    dysfunction,hypertension,

    peptic ulceration,GI bleeding,

    pregnancy,lactation, impaired

    hepatic and renalfunction.

    y Asseibupr

    y Assecolorophth

    evaluevalu

    sensaclott

    y Admor afoccu

    y Use suggover

    y Avoidrug

    y Instrany s

    y Reporash,

    swel

    visio

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    bronchospasm,

    rhinitis

    y OTHER:peripheral edema,anaphylactoidreactions to

    anaphylactic shock

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    Name of Drug General Action Specific Action Adverse Effect Indication Contraindication Nursin

    Ponstan

    (Mefenamic acid)8F 5ml TID in

    between Dolan syrup

    NSAID Anti-inflammatory,

    analgesics, andantipyretic activities

    related to inhibition ofprostaglandin synthesis,

    exact mechanism ofaction are not known.

    CNS:Headache,

    dizziness, somnolence,insomnia, fatigue,

    tiredness, tinnitus,ophthalmic effects.

    DERMATOLOGIC:Rash, pruritus,

    sweating, dry mucousmembranes, stomatitis.

    GI:Nausea, dyspepsia,GI pain, diarrhea,

    vomiting, constipation,flatulence.

    GU: Dysuria, renalimpairment.

    HEMATOLOGIC:Bleeding, platelet

    inhibition with higherdoses, neutropenia,

    eosinophilia,leukopenia,

    pancytopenia,thrombocytopenia,

    agranulocytosis,granulocytopenia,

    aplastic anemia,decreased Hgb orHct,

    bone marrowdepression,

    menorrhagia.

    Relief ofmoderate pain

    when therapywill not exceed

    1 week. Treatment of

    primary

    dysmenorrheal.

    Contraindicated withhypersensitivit

    y tomefenamic

    acid, aspirinallergy, and as

    treatment ofperioperative

    pain withcoronary artery

    bypassgrafting.

    Use cautiouslywith asthma,

    renal orhepatic

    impairment,peptic ulcer

    disease, GIbleeding,

    hypertension,heart failure,

    pregnancy,lactation.

    BEFOR

    1. Assesrenal, he

    conditiolactation

    2. Assesskin colo

    orientatiophthalm

    audiomeperipher

    adventitievaluatio

    time, LFtest; seru

    guaiac.DURIN

    1. Be awbe at an

    events, Gaccordin

    2. Give wdecrease

    3. Arranophthalm

    during lo4. If ove

    emergensupporti

    induced

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    RESPIRATORY:Dyspnea, hemoptysis,

    pharyngitis,bronchospasm, rhinitis.

    OTHER:Peripheraledema, anaphylactoid

    reactions toanaphylactic shock.

    charcoal

    cathartic

    AFTER1. Instruwith foo

    prescribthe drug

    week.2. Instru

    and cons

    providerdigestive

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    Name of Drug General Action Specific Action Adverse Effect Indication Contraindication Nursin

    Catapres 75mg tab

    BID

    Antihypertensive

    A2- adrenergicagonist

    Clonidine treats high

    blood pressure bystimulating 2 receptors

    in the brain, whichdecreases cardiac output

    and peripheral vascularresistance, lowering

    blood pressure. It hasspecificity towards the

    presynaptic 2 receptorsin the vasomotor center

    in the brainstem. Thisbinding decreases

    presynaptic calciumlevels, and inhibits the

    release ofnorepinephrine (NE).

    The net effect is adecrease in sympathetic

    tone.

    Body as a Whole:Fatigue, fever,headache, pallor,

    weakness, andwithdrawal syndrome.

    Also reported were aweakly positive

    Coombs' test andincreased sensitivity to

    alcohol.

    Cardiovascular:Bradycardia,congestive heart

    failure,electrocardiographic