analyte quarterly 2012q4
DESCRIPTION
The broadest selection of analytes acrossa wide range of disease states, including metabolic disease, inflammation, neurodegenerative disease, toxicity,cancer and more. All the components and reagents you need to detect multiple analytes simultaneously in a small sample size (10-50 μL)—all in a single kit, using a single catalogue number.TRANSCRIPT
Analyte Quarterly Q4 2012
Immunoassays & MILLIPLEX® map KitsThe #1 Best Seller for Multiplexing using Luminex® technology
• Bone Metabolism
• Cancer
• Cardiovascular Disease
• Cell Signaling
• Cellular Metabolism
• Inflammation/Immunology
• Metabolism
• Neuroscience
• Stem Cell Characterization
• Toxicity
EMD Millipore is a division of Merck KGaA, Darmstadt, Germany
The Latest in Multiplexing & ELISAsDiscover the Latest in Innovative and Unique Assay Kits, Instruments and ServicesMILLIPLEX® map Multiplex Immunoassay Kits
Magnetic Bead Format Kit Species Catalogue No.
Cancer/Metastasis Panel Biomarker 1 Human HCMBMAG-22K
Early Apoptosis Signaling - 7 Plex 48-669MAG
Kidney Toxicity Panel 1 Canine CKTX1MAG-97K
Late Apoptosis Signaling - 3 Plex Human 48-670MAG
MAPK/SAPK Signaling - 10 Plex 48-660MAG
Neurodegenerative Disease Panel 2 Human HNDG2MAG-36K
Cytokine/Chemokine Porcine PCYTMAG-23K
Cytokine/Chemokine - 13 Plex Premix Porcine PCYTMG-23K-13PX
Soluble Cytokine Receptor Mouse MSCRMAG-42K
Src Family Kinase Active Site - 8 Plex
48-650MAG
Stem Cell Pluripotency Panel 1 Human 48-617MAG
T-Cell Receptor - 7 Plex 48-690MAG
Th17 - 25 Plex Premix Human HT17MG-14K-PX25
ELISA Kits• Cytokine ELISAs
• FGF-23 (Rat / Mouse) - 10-pack
• Glucagon (Human / Rat / Mouse)
• Glucagon (Human / Rat / Mouse) - 10-pack
• GLP-1 HS (Active) (Multispecies) - 10-pack
• GLP-2 (Total) (Rat / Human) - 10-pack
MAGPIX® Instrument• Multiplex analyte detection system
(See page 21)
Services• Biomarker Services
(See back cover)
New MILLIPLEX® Analyst 5.1 Software!You asked for new and enhanced features and
we listened! Our new software provides you with
the data you need, combining speed and accuracy,
even at the lowest part of
the curve. For details,
see page 22.
20% OFFMILLIPLEX® Analyst 5.1 Software one- or five-seat licenses now through December 31, 2012(Use promo code ZBIOS584)
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For Research Use Only.emdmillipore.com/analytes_q4
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MILLIPLEX® MAP & ELISAs— New Product Spotlight
Discover the most versatile assay platform for
autoimmune disease and immunology research.
T-cell differentiation and cytokine secretion
regulate immune response, chronic inflammation,
autoimmune diseases and cancer. Get the most
information from each sample with our Human
and Mouse Th17 panels that enable you to
quantify signature cytokines from not only Th17
cells but, Th1 and Th2 cell subsets as well. With
this broader analytical scope, you can expand
each experiment beyond Th17 cytokines.
Immunology: MILLIPLEX® MAP Human and Mouse(Cat. No. HTH17MAG-14K)(Cat. No. MTH17MAG-47K)
Figure 1A and 1B. Examination of cytokine response in mouse plasma at various time points after an in vivo LPS-challenge.
Cell Signaling: MILLIPLEX® MAP TGFβ Pathway 6-Plex Panel(Cat. No. 48-614MAG)
Understanding regulation of the TGFβ signaling
network requires simultaneous analysis of
multiple, mutually interacting signaling proteins.
The MILLIPLEX® MAP TGFβ Pathway 6-Plex Panel,
based on the Luminex® xMAP® technology, moves
your research faster by enabling you to quantify
multiple Smads and other TGFβ pathway proteins
simultaneously. Use Iess sample. Get more data.
Better data than you ever got from Western
blotting!
Advantages of MILLIPLEX® MAP Cell Signaling Kits
over traditional cell signaling assays:
• Analyze dozens of samples using a
96-well plate
• Analyze time course or dose response curves,
alI in one assay
• Measure concentrations of multiple total or
phosphorylated proteins in the same well
• Use median fluorescence intensity to measure
fold increases comparing stimulated and
unstimulated cell cultures or tissue lysates
• Validated using Western blotting and IP
Figure 2A and 2B. TGFβ pathway proteins were simultaneously detected in two sets of human tissue samples (20 μg/well). Phospho-Smad2 was significantly elevated in breast cancer tissue samples.
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IL-13 IL-17F IL-17A
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IL-6 IL-22 TNF IL-10 IFNγ
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Breast Normal 2Breast Cancer 2
TGFβ2 pERK pSmad2 pAkt pSmad3 Smad4 0
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.Toxicity: MILLIPLEX® MAP Rat Kidney Toxicity Magnetic Bead Panel 1(Cat. No. RKTX1MAG-37K)
Metabolism: ELISA - Circulating Glucagon(Cat. No. EZGLU-30K)(Cat. No. EZGLU-30BK)
Toxicity is the leading cause of drug failure, so
increasing the success rate of therapeutic
development requires more sensitive and rapid
methods to determine organ-specific damage.
The traditional tests to determine kidney toxicity
are blood urea nitrogen (BUN) and serum
creatinine (SCr), which are not optimal for early
detection or localization of kidney damage. As a
result, researchers have turned to recently
qualified nephrotoxicity biomarkers for more
predictive toxicity analysis. We have developed
the MILLIPLEX® MAP Rat Kidney Toxicity Magnetic
Bead Panels 1 and 2, containing a total of 14
kidney toxicity biomarkers.
We used these panels to efficiently profile
response to gentamicin, a known nephrotoxicant
in rats. By simply measuring biomarker
concentrations in urine, we detected kidney
toxicity (marked by increased Clusterin and
KIM-1 levels) in as few as three days (Figure 3).
Glucagon is the most important counter-
regulatory hormone to insulin in blood glucose
homeostasis. It stimulates gluconeogenesis and
glycogenolysis while inhibiting glycogenesis and
glycolysis mainly in the liver. Recently, glucagon
and its receptors have been actively pursued as
therapeutic targets for Type I diabetes. However,
quantifying glucagon in blood has been
challenging due to glucagon’s many
immunoreactive forms.
EMD Millipore’s new, highly specific glucagon
ELISA kit shows no cross-reactivity to
miniglucagon or glucagon 1–18 and < 5%
cross-reactivity to oxyntomodulin. This assay,
including sample extraction using our rapid
protocol (Figure 4B), can be completed within a
working day. In contrast to kits from competing
suppliers, results from our ELISA kit agree well
with published glucagon levels.
Figure 3A and 3B. 3 groups of 5 adult male Sprague Dawley® rats, each injected intraperitoneally daily with either water, low-dose (70 mg/kg) gentamicin or high-dose (140 mg/kg) gentamicin. Day 0 urine collection is after the 1st dose, and subsequent collections are at
days 3, 7 and 14. All nephrotoxicity biomarkers were analyzed, but we show data here only for Clusterin and KIM-1. Analyte concentrations in gentamicin treated animals spike at day 3 for both Clusterin and KIM-1, and decrease at days 7 and 14.
Figure 4. A. EMD Millipore’s Glucagon ELISA (Cat. No. EZGLU-30K) kit exhibits sensitive, precise detection of full length, porcine glucagon with low interassay variation. B. Correlation of glucagon measurements following sample extraction using rapid acetonitrile extraction (y-axis) with measurements following extraction using solid phase extraction (x-axis).
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Y = 1.024(x) + 2.06r = 0.903
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Sample Results Using Waters HLB Extraction Plate, pg/ml
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H2Olow dose gentamicinhigh dose gentamicin
KIM-1
Day 0 Day 3 Day 7 Day 14
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For Research Use Only.
EMD Millipore provides an unparalleled level of peer support—scientists working with scientists—to provide you with the
quality tools and services you need to do your best work. With a wide range of ELISAs and RIAs, we advance your research
in many research areas including metabolic disease (diabetes, obesity, cardiovascular), inflammation, immunology,
neuroscience, oncology and cell signaling. Plus, some of our most popular ELISAs are available a 10-pack format.
ELISAs & RIAs
Kit Species Catalogue No.
a-Synuclein Human/Rat/Mouse
NS400
Amyloid Beta, 1-40 Human EZHS40
Amyloid Beta, 1-42 Human EZHS42
Amyloid Beta, SET Human EZHS-SET
Amyloid Beta (Brain), 1-40
Human EZBRAIN40
Amyloid Beta (Brain), 1-42
Human EZBRAIN42
Amyloid Beta (Brain), SET
Human EZBRAIN-SET
Brain Derived Neurotrophic Factor (ChemiKine™)
Human/Rat CYT306
Glial fibrillary acidic protein (GFAP)
Human/Rat/ Mouse
NS830
Nerve Growth Factor (ChemiKine™)
Rat/Mouse CYT304
Neuropeptide S (NPS) Human EZHNPS-34K
Kit Species Catalogue No.
IL-2 Human NEW! EZHIL2
IL-2 Mouse NEW! EZMIL2
IL-4 Human NEW! EZHIL4
IL-4 Mouse NEW! EZMIL4
IL-6 Human NEW! EZHIL6
IL-6 Mouse NEW! EZMIL6
IL-10 Human NEW! EZHIL10
IL-10 Mouse NEW! EZMIL10
TNFa Human NEW! EZHTNFA
TNFa Mouse NEW! EZMTNFA
Kit Species Catalogue No.
Neuropeptide Y (NPY) Human EZHNPY-25K
Neuropeptide Y (NPY) Rat/Mouse EZRMNPY-27K
Phosphorylated Neurofilament (pNF-H)
Multi-species
NS170
Pigment Epithelium Derived Factor (ChemiKine™)
Human CYT420
S100B Human EZHS100B-33K
SAA-3 Mouse EZMSAA3-12K
Neuroscience ELISAs
Neuroscience ELISAs, continued*Cytokine ELISAs
emdmillipore.com/analytes_q4
* 10-Pack Format —Now Available for Select Kits! Kit Species Catalogue No.
Adiponectin Human EZHADP-61K10 - Pack EZHADP-61BK
Adiponectin Mouse EZMADP-60K10 - Pack EZMADP-60BK
Adiponectin Rat EZRADP-62K
Adiponectin Canine EZCADP63K
Adiponectin – High Molecular Weight
Human EZHMWA-64K
10 - Pack EZHMWA-64BK
Adipsin Mouse EZMADPSN-22
Amylin (active)• Human EZHA-52K10 - Pack EZHA-52BK
Amylin (total)• Human EZHAT-51K
Apo AIV Human EZHAPOA4-73K
BDNF Human/Rat CYT306
Chemerin Human EZHCMRN-57K
C-Peptide Human EZHCP-20K10 - Pack EZHCP-20BK
C-Peptide 2 Rat/Mouse EZRMCP2-21K
CRP Human CYT298
CRP Rat CYT294
CRP Canine CYT296
FGF-21 Human EZHFGF21-19K
FGF-21 Rat/Mouse EZRMFGF21-26K
ELISA — Circulating Biomarkers
ELISA / R
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.ELISA — Circulating Biomarkers, continued
* Coming Soon • Solid Plate Format † CU.S. Patent #: 5,541,066: 5,780,240 ▪ Requires Sample Extraction
ELISA — Other Assays EZ-Transcription Factor
ELISA — Other Assays Extracellular Matrix
DescriptionColorimetric
Catalogue No.Chemiluminescent
Catalogue No.
AP-1 Family 70-550 70-650
c-Fos 70-545 70-645
c-Jun 70-540 70-640
ErbB2 (Tyr1248) 17-490
HDAC 17-374
Jun/Fos 70-546 70-646
NFkB Family 70-560 70-660
NFkB p50 70-515 70-615
NFkB p50/p65 70-510 70-610
NFkB p65 70-520 70-620
PI3 Kinase Activity/Inhibitor
17-493
PhosphaFluor HTS OmniPhosphatase
17-448
Ras Activation 17-497
ssDNA Apoptosis APT225
Universal TF 70-501 70-601
Kit Species Catalogue No.
Fibronectin Human ECM300
sCD26 Human ECM345
sE-Selectin Human ECM330
sICAM-1 Human ECM335
sICAM-2 Human ECM346
sICAM-3 Human ECM337
sL-Selectin Human ECM331
sVCAM-1 Human ECM340
Kit Species Catalogue No.
FGF-23 Human EZHFGF23-32K10 - Pack EZHFGF23-32BK
FGF-23 Rat EZRFGF23-42K10 - Pack NEW! EZRFGF23-42BK
FGF-23 Mouse EZMFGF23-43K10 - Pack NEW! EZMFGF23-43BK
Ghrelin (active) Human EZGRA-88K10 - Pack EZGRA-88BK
Ghrelin (active) Rat/Mouse EZRGRA-90K
Ghrelin (total) Human EZGRT-89K10 - Pack EZGRT-89BK
Ghrelin (total) Rat EZRGRT-91K
GIP (total) Human EZHGIP-54K10 - Pack EZHGIP-54BK
GIP (total) Rat/Mouse EZRMGIP-55K10 - Pack EZRMGIP-55BK
GLP-1 (active) • Multispecies EGLP-35K10 - Pack EGLP-35BK
GLP-1 High Sensitivity (active)
Multispecies EZGLPHS-35K
10 - Pack NEW! EZGLPHS-35K
GLP-1 (total) Multispecies EZGLP1T-36K10 - Pack EZGLP1T-36BK
GLP-2 (total) Human/Rat EZGLP2-37K10 - Pack NEW! EZGLP2-37BK
Glucagon ▪ Human/Rat/Mouse
NEW! EZGLU-30K
10 - Pack NEW! EZGLU-30BK
Growth Hormone Rat/Mouse EZRMGH-45K10 - Pack EZRMGH-45BK
IFNa Human Cyt271
Insulin Human EZHI-14K10 - Pack EZHI-14BK
Insulin Rat/Mouse EZRMI-13K10 - Pack EZRMI-13BK
Insulin (Animal Serum Free) Human EZHIASF-14K
Laminin Human ECM310
Leptin Dual Range Human EZHL-80SK10 - Pack EZHL-80BK
Leptin Mouse EZML-82K10 - Pack EZML-82BK
Leptin Rat EZRL-83K10 - Pack EZRL-83BK
Leptin Canine EZCL-31K
Nerve Growth Factor (ChemiKine™)
Rat/Mouse CYT304
Omentin-1 Human EZH0MNTN1-29K
Pancreatic Polypeptide Human EZHPP40K10 - Pack EZHPP-40BK
PEDF (ChemiKine™) Human CYT420
ELIS
A /
RIA
Kit Species Catalogue No.
Procollagen Type IIA - N-Propeptide (PIIANP)†
Human EZPIIANP-53K
Proinsulin (Intact) Human EZHIPI-17K
Proinsulin (total) Human EZHPI-15K10 - Pack EZHPI-15BK
PYY (total) Human EZHPYYT66K10 - Pack EZHPYYT-66BK
RBP4 Human EZHRBP4-18K
Resistin Human EZHR-95K10 - Pack EZHR-95BK
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For Research Use Only.
Description Catalogue No.
AKT1 (total) 17-455
EGFR (total) 17-460
Erk 1/2 (total) 17-463
FAK (total) 17-479
Insulin Receptor (β subunit) (total) 17-483
IkB (total) 17-485
JNK 1/2 (total) 17-465
MEK1 (total) 17-473
Met (total) 17-469
p38a (total) 17-487
PRAS40 (total) 17-477
Src (total) 17-467
phospho-Akt (Ser473) 17-457
phospho-Akt (Thr308) 17-456
phospho-EGFR (Tyr1068) 17-462
phospho-EGFR (Tyr1173) 17-461
phospho-FAK (Tyr397) 17-480
phospho-IR (β Subunit) (Tyr 1162/1163) 17-484
phospho-IRS1 (Ser307 mouse/Ser312 Human)
17-459
phospho-IkB (Ser32) 17-486
phospho-JNK 1/2 (Thr183/Tyr185) 17-466
phospho-MEK1 (Ser218/222) 17-474
phospho-MET (Tyr1230/Tyr1234/Tyr1235) 17-470
phospho-p38a (Thr180/Tyr182) 17-488
phospho-p53 (Ser15) 17-475
phospho-PRAS40 (Thr246) 17-478
ELISA — Cell Signaling / Intracellular Star ELISAs
Formerly EMD Chemicals ELISAs, continued
Formerly EMD Chemicals ELISAs
RIA
Kit Species Catalogue No.
PMN Elastase/a1-PI Complex
Human QIA96
TGFa Human QIA61
TIMP-1 Human QIA54
TIMP-2 Multi-species QIA40
Soluble t-PA Human QIA99
VEGF Human QIA52
Total Bcl-2 Human QIA23
Cathepsin D (Rapid Format)
Human QIA29
COX-2 Human CBA053
Total CREB HumanMouse
CBA071
Total c-ErbB2/c-Neu (Rapid Format) PhosphoDetect™
Human QIA10
ERK1/2 (Thr185/Tyr187) HumanRatMouse
CBA006
For technical support and ordering, visit: www.emdmillipore.com/chemicals
Kit Species Catalogue No.
Adiponectin Human HADP-61HK
Adiponectin Mouse MADP-60HK
C-Peptide Human HCP-20K
C-Peptide Rat RCP-21K
C-Peptide Canine CCP-24HK
C-Peptide Porcine PCP-22K
Ghrelin (active) Human GHRA-88HK
Ghrelin (total) Human GHRT-89HK
GLP-1 (active) Multi-species GLP1A-35HK
GLP-1 (total) Multi-species GLP1T-36HK
Glucagon Multi-species GL-32K
Insulin Rat RI-13K
Insulin Porcine PI-12K
Insulin Lispro LPI-16K
Insulin Specific Human HI-14K
Insulin Ultra Sensitive Human HI-11K
Insulin Rat SRI-13K
Leptin Human HL-81K
Leptin Mouse ML-82K
Leptin Rat RL-83K
Leptin Multi-species XL-85K
Proinsulin Human HPI-15K
PYY Rat/Mouse RMPYY-68HK
PYY (3-36) Specific Human PYY-67HK
PYY (total) Human PYYT-66HK
ELISA / R
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ELISA — Cell-based Assays Dual Detect CELISAs™Description Catalogue No.
ErbB2 (Tyr1248) 17-490
H2A.X (Ser139) 17-720
Kit Species Catalogue No.
Frataxin Human EAMT002
FasL Human QIA27
Galectin-3 Human QIA112
Lactoferrin Human 427275
MMP-1 Human QIA55
MMP-2 Human QIA63
MMP-9 Human QIA56
MMP-13 Human QIA130
Myeloperoxidase Human 475919
6
MILLIPLEX® mapYour Source for Simultaneous Multi-Analyte Detection— the Voice of Luminex® xMAP® Technology
• The broadest selection of analytes across a wide range of disease states, including metabolic disease, inflammation, neurodegenerative disease, toxicity, cancer and more.
• All the components and reagents you need to detect multiple analytes simultaneously in a small sample size (10-50 µL)—all in a single kit, using a single catalogue number.
• Available in a magnetic bead format. Magnetic polystyrene beads contain encapsulated magnetite with bead surface chemistries that are comparable to nonmagnetic beads. New magnetic bead panels will be introduced into our portfolio each quarter!
• Select a premixed kit or choose analytes within a panel to design a custom kit.
• Quality controls provided to qualify assay performance.
• Analytically validated panels that yield consistent analyte profiles irrespective of plex size.
• Standardized standard curve ranges across analytes and lots to ensure lot-to-lot consistency.
• Panels meet stringent manufacturing criteria to ensure batch-to-batch reproducibility.
• Environmentally friendly packaging: our boxes are 100% recyclable to reduce ecological footprints.
• Consolidated packaging available for larger orders to reduce storage needs.
emdmillipore.com/analytes_q4For R
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MetabolismHuman Adipokine Panel 1Serum/Plasma Samples(Cat. No. HADK1MAG-61K)
Adiponectin
Adipsin
Lipocalin-2/NGAL
PAI-1 (total)
Resistin
Human Adipokine Panel 2Serum/Plasma Samples(Cat. No. HADK2MAG-61K)
HGF
IL-1βIL-6
IL-8
Insulin
Leptin
MCP-1
NGF
TNFa
Human AdipocyteCell Culture Samples(Cat. No. HADCYMAG-61K)
Adiponectin
HGF
IL-1βIL-6
IL-8
Leptin
MCP-1
NGF
PAI-1 (total)
Resistin
TNFa
Mouse AdipokineSerum/plasma samples(Cat. No. MADPK-71K) MB Format Coming Soon*
IL-6
Insulin
Leptin
MCP-1
PAI-1 (total)
Resistin
TNFa
Mouse AdipocyteCell culture samples(Cat. No. MADPCYT-72K) MB Format Coming Soon*
Adiponectin
IL-6
Leptin
MCP-1
PAI-1 (total)
Resistin
TNFa
Rat AdipokineSerum/plasma samples(Cat. No. RADPK-81K) NEW!
IL-1βIL-6
Insulin
Leptin
MCP-1
PAI-1 (active)†
PAI-1 (total)†
TNFa
Rat AdipocyteCell culture samples(Cat. No. RADPCYT-82K)
Adiponectin
IL-1βIL-6
Leptin
MCP-1
PAI-1 (active)†
PAI-1 (total)†
TNFa Human Metabolic Hormone(Cat. No. HMHMAG-34K)
Amylin (active)†
Amylin (total)†
C-Peptide
Ghrelin (active) %
GIP (total)
GLP-1 (active)
Glucagon
IL-6
Insulin
Leptin
MCP-1
Pancreatic Polypeptide
PYY (total)
TNFa
Mouse Metabolic Hormone(Cat. No. MMHMAG-44K)
Amylin (active)
C-Peptide 2
Ghrelin (active) %
GIP (total)
GLP-1 (active)
Glucagon
IL-6
Insulin
Leptin
MCP-1
Pancreatic Polypeptide
PYY (total)
Resistin
TNFa
Rat Metabolic Hormone(Cat. No. RMHMAG-84K)
Amylin (active)
C-Peptide 2
Ghrelin (active) %
GIP (total)
GLP-1 (active)
Glucagon
IL-6
Insulin
Leptin
MCP-1
Pancreatic Polypeptide
PYY (total)
TNFa
Non-Human Primate Metabolic Hormone(Cat. No. NHPMHMAG-45K)
Amylin (active)
C-Peptide
Ghrelin (active) %
GIP (total)
GLP-1 (active)
Glucagon
IL-6
Insulin
Leptin
MCP-1
Pancreatic Polypeptide
PYY (total)
TNFa
Human Liver Protein(Cat. No. HLPPMAG-57K)
AFP
ANGPTL3
ANGPTL4
ANGPTL6
FABP1
FGF-19
FGF-21
FGF-23
HGF
Human Gut Hormone(Cat. No. HGT-68K)
Amylin (active)†
Amylin (total)†
Ghrelin (active) %
GIP (total)
GLP-1 (active)
Insulin
Leptin
Pancreatic Polypeptide
PYY (total)
Mouse Gut Hormone(Cat. No. MGT-78K)
Amylin (active)
Ghrelin (active) %
GIP (total)
GLP-1 (active)
Insulin
Leptin
Pancreatic Polypeptide
PYY (total)
Rat Gut Hormone(Cat. No. RGT-88K)
Amylin (active)
Ghrelin (active) %
GIP (total)
GLP-1 (active)
Insulin
Leptin
Pancreatic Polypeptide
PYY (total)
Canine Gut Hormone(Cat. No. CGTMAG-98K)
Amylin (total)
Ghrelin (active) %
GIP (total)
GLP-1 (active)
Glucagon
Insulin
Leptin
Pancreatic Polypeptide
PYY (total)
% Requires a protease inhibitor during sample collection
† Cannot be plexed together: 1) Amylin (active) and Amylin (total) 2) PAI-1 (active) and PAI-1 (total)
Non-magnetic bead format
For Research Use Only.M
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.Metabolism Bone Metabolism
Human Bone Panel(Cat. No. HBNMAG-51K)
ACTH
DKK1
FGF-23
IL-1β
IL-6
Insulin
Leptin
OPG
Osteocalcin
Osteopontin
PTH
SOST
TNFa
Human Bone Panel 1ASerum/plasma samples(Cat. No. HBN1A-51K) **
ACTH
Insulin
Leptin
OPG
Osteocalcin
Osteopontin
PTH
Human Bone Panel 1BTissue culture samplesCat. No. HBN1B-51K) **
ACTH
Adiponectin
IL-1β
IL-6
Insulin
Leptin
OPG
Osteocalcin
Osteopontin
PTH
TNFa
Mouse Bone Panel 1ASerum/plasma samples(Cat. No. MBN1A-41K)
ACTH
IL-6
Insulin
Leptin
OPG
TNFa
Mouse Bone Panel 1BTissue culture samples(Cat. No. MBN1B-41K)
ACTH
IL-6
Insulin
Leptin
OPG
Osteocalcin
TNFa
Human Pituitary Panel 1 (Cat. No. HPTP1MAG-66K)
ACTH
AGRP
CNTF
FSH
GH
LH
TSH
Human Pituitary Panel 2(Cat. No. HPTP2MAG-66K)
BDNF Prolactin
Non-Human Primate Pituitary Panel 1 (Cat. No. NHPPT1MG-46K)
ACTH
AGRP
CNTF
FSH
GH
LH
TSH
Non-Human Pituitary Panel 2(Cat. No. NHPPT2MG-46K)
BDNF
Prolactin
Mouse Pituitary(Cat. No. MPTMAG-49K)
ACTH
BDNF
FSH
GH
LH
Prolactin
TSH
Rat Pituitary(Cat. No. RPTMAG-86K)
ACTH
BDNF
FSH
GH
LH
Prolactin
TSH
Canine Pituitary N(Cat. No. CPTMAG-96K)
ACTH
BDNF
FSH
GH
LH
Prolactin
TSH
Rat Stress Hormone(Cat. No. RSH69K)
ACTH
Corticosterone
Melatonin
Multi Species Steroid/ Thyroid Hormone(Cat. No. STTHMAG-21K) n
Cortisol
Estradiol
Progesterone
T3
T4
Testosterone*
Human IGF Binding Protein(Cat. No. HIGFBP-53K) MB Format Coming Soon*
IGFBP1
IGFBP2
IGFBP3
IGFBP4
IGFBP5
IGFBP6
IGFBP7
Mouse IGF Binding Protein(Cat. No. MIGFBPMAG-43K)
IGFBP1
IGFBP2
IGFBP3
IGFBP5
IGFBP6
IGFBP7
Single Plex KitsAdiponectin (Mouse)
Adiponectin (Rat)
IGF-1 (Mouse/Rat)
IGF-1 (Human)**n
MADPK-71K-ADPN
RADPK-81K-ADPN
RMIGF187K
Human IGF(Cat. No. HIGFMAG-52K) NEW!
IGF-1 (Human)*n IGF-2 (Human)*n
MIL
LIPL
EX®
ma
p C
IRC
ULA
TIN
G
MET
ABO
LISM
/ B
ON
E M
ETA
BOLI
SM
9
For Research Use Only.
Mouse Bone Panel 2ASerum/plasma samples(Cat. No. MBN2A-41K)
ACTH
IL-6
Insulin
Leptin
RANKL
TNFa Mouse Bone Panel 2BTissue culture samples(Cat. No. MBN2B-41K)
ACTH
IL-6
Insulin
Leptin
Osteocalcin
RANKL
TNFa
Rat Bone Panel 1(Cat. No. RBN1-31K)
ACTH
Insulin
Leptin
OPG
Rat Bone Panel 2(Cat. No. RBN2-31K)
ACTH
Insulin
Leptin
RANKL
Rat Bone Panel 3(Cat. No. RBN3-31K)
Osteocalcin
Osteopontin
PTH
Single Plex Bone KitsOsteocalcin (Mouse)
Osteocalcin (Rat)
RANKL (Human)
RANKL (Mouse)
RANKL (Rat)
OPG (Mouse)
OPG (Rat)
MBN-41K-1OC
RBN-31K-1OC
HBN51K1RANKL
MBN-41K-1RANKL
RBN-31K-1RANKL
MBN-41K-1OPG
RBN-31K-1OPG
CardiovascularHuman CVD Panel 1(Cat. No. HCVD1MAG-67K)
BNP
NT proBNP
CK-MB
CXCL6/GCP-2
CXCL16
Endocan-1 (ESM-1)
FABP3
FABP4
LIGHT
Oncostatin (OSM)
Placental Growth Factor (PIGF)
Troponin I (TnI)
Human CVD Panel 2(Cat. No. HCVD2MAG-67K)
ADAMTS13
GDF-15
D-dimer
sICAM-1
MPO
Myoglobin
Lipocalin-2/NGAL
Serum Amyloid A
sVCAM-1
sP-Selectin
Human CVD Panel 3 (Acute Phase)(Cat. No. HCVD3MAG-67K)
a-2-Macroglobulin
Adipsin
AGP
CRP
Fetuin A
Fibrinogen
Haptoglobin
sL-Selectin
Platelet Factor 4 (PF4)
Serum Amyloid P
von Willebrand Factor
Human CVD Panel 4 (Cat. No. HCVD4MAG-67K)
sE-Selectin
Follistatin (FST)
dPAPP-A
Pecam-1
Pentraxin-3 (PTX3)
Tissue Factor (TF)
Thrombomodulin
Tropinin T (TnT)
* Coming Soon
** Discontinued non-magnetic bead format December 31, 2012
n Requires Sample Extraction
Non-magnetic bead format
Human CVD1(Cat. No. HCVD1-67AK)
MMP-9
MPO
PAI-1 (total)
sE-Selectin
slCAM-1
sVCAM-1
Human CVD2(Acute phase proteins)(Cat. No. HCVD2-67BK)
CRP Serum Amyloid P
Human CVD3(Cat. No. HCVD3-67CK)
IFNγ
IL-1β
IL-6
IL-8
IL-10
MCP-1
NT-proBNP
TNFa
VEGF
Human Apolipoproteins(Cat. No. APO-62K) MB Format Coming Soon*
Apo AI
Apo AII
Apo B
Apo CII
Apo CIII
Apo E
Mouse CVD1(Cat. No. MCVD1-77AK) MB Format Coming Soon*
MMP-9
PAI-1 (total)
sE-Selectin
slCAM-1
sVCAM-1
Mouse CVD2(Cat. No. MCVD277BK) MB Format Coming Soon*
Adiponectin
Apo AI
Apo E
Fibrinogen
Mouse Acute Phase Panel 1 (Cat. No. MAP1MAG-76K)
Lipocalin-2/NGAL
Pentraxin-3 (PTX3)
Serum Amyloid A-3 (SAA-3)
BON
E META
BOLISM
/ CV
D
10
For R
esea
rch
Use
Only
.
Human Circulating Cancer Biomarker Panel 1(Cat. No. HCCBP1MAG-58K)
AFP
CA125
CA15-3
CA19-9
CEA
CYFRA21-1
FGF-2/FGF-basic
HCGβHE4
HGF
IL-6
IL-8
Leptin
MIF
Osteopontin
Prolactin
PSA (free)†
PSA (total)†
SCF
sFas
sFasL
TGFaTNFaTRAIL
VEGF
Human Circulating CancerBiomarker Panel 2(Cat. No. HCCBP2MAG-58K)
Antithrombin III
Coagulation factor XIII
Complement factor H (CFH)
Extracellular matrix protein 1 (ECM1)
Vitamin D binding protein
Vitronectin
Human Circulating Cancer Biomarker Panel 3Cat. No. HCCBP3MAG-58K)
Catalase
Cathepsin D
Ferritin
Fibroblast activation protein (FAP)
Galectin 3
IGFBP3
Melanoma inhibitory activity (MIA)
Myeloperoxidase (MPO)
Sex hormone binding globulin (SHBG)
Human Cancer / Metastasis Biomarker Panel 1(Cat. No. HCMBMAG-22K) NEW!
DKK1
GDF15
NSE
OPG
Osteonectin (SPARC)
Periostin
TRAP
TWEAK
YKL40
Cancer BiomarkerCardiovascular, continued
NeuroscienceHuman Neurodegenerative Disease Panel 1(Cat. No. HNDG1-36K) ** (Cat. No. HNDG1MAG-36K)
a-2-Macroglobulin
Apo AI
Apo CIII
Apo E
Complement C3
Complement Factor H
Prealbumin
Human Neurodegenerative Disease Panel 2(Cat. No. HNDG2-36K) ** (Cat. No. HNDG2MAG-36K) NEW!
a-1-Antitrypsin
Complement C4
CRP
MIP-4
PEDF
SAP
Mouse Acute Phase Panel 2 (Cat. No. MAP2MAG-76K)
Adipsin
a-1-Acid glycoprotein (AGP)
a-2-Macroglobulin
CRP
Haptoglobin
Serum Amyloid P
Pentraxin-2
Rat CVD1(Cat. No. RCVD1-89K) MB Format Coming Soon*
BNP
IL-6
MCP-1
MPO
PAI-1
TIMP-1
TNFa
Troponin I
Troponin T
VEGF
von Willebrand Factor
Rat CVD2(Cat. No. RCVD2-89K) MB Format Coming Soon*
sE-Selectin
sICAM-1
* Coming Soon
** Discontinued non-magnetic bead format December 31, 2012
† Cannot be plexed together: 1) PSA (free) and PSA (total)
n Requires Sample Extraction
Non-magnetic bead format
CV
D /
CA
NC
ER /
NEU
ROSC
IEN
CE
Human Angiogenesis / Growth Factor(Cat. No. HAGP1MAG-12K)
Angiopoietin-2
BMP-9
EGF
Endoglin
Endothelin-1
FGF-1/FGF-acidic
FGF-2/FGF-basic
Follistatin
G-CSF
HB-EGF
HGF
IL-8
Leptin
PLGF
VEGF-A
VEGF-C
VEGF-D
Mouse Angiogenesis / Growth Factor Panel 1MB Format Coming Soon*
sALK-1
Amphiregulin
Angiopoietin-2
Betacellulin
sCD31/PECAM-1
EGF
Endoglin
Endothelin-1
sFASL
FGF-2
Follistatin
G-CSF
HGF
IL-1β
IL-6
IL-17A
KC/CXCL1
Leptin
MCP-1
MIP-1aPLGF-2
Prolactin
SDF-1
TIMP-1
TNFaVEGF-A
VEGF-C
VEGF-D
11
Toxicity
Human Neurodegenerative Disease Panel 3(Cat. No. HNDG3-36K) ** (Cat. No. HNDG3MAG-36K)
BDNF
Cathepsin D
MPO
PAI-1 (total)
PDGF-AA
PDGF-AB/BB
RANTES
sICAM-1
sNCAM
sVCAM-1
Human Neurodegenerative Disease Panel 4CSF Samples(Cat. No. HNDG4MAG-36K)
Aβ1-40
Aβ1-42
GDNF
S100B
sRAGE
Human Neurological Disorders Panel 1CSF Samples(Cat. No. HND1MAG-39K)
a-Synuclein
NGFβNSE
PARK5/UCHL1
PARK7/DJ1
Tau (Thr231)
Tau (total)
Human Neurological Disorders Panel 2(Cat. No. HND2MAG-39K)
AGP
CP
HP
Serum Amyloid P
Human Neurological Disorders Panel 3MB Format Coming Soon*
a1-antichymotrypsin
Contactin-1
Contactin-2
Neurofilament L (NF-L)
Neurotrophin-4 (NT-4)
Osteopontin (OPN)
SOD1
Human Neuropeptide n
(Cat. No. HNPMAG-35K)
a-MSH
β-Endorphin
Cortisol
Melatonin
Neurotensin
Orexin A
Oxytocin
Substance P
Human Kidney Toxicity Panel 1Serum samples(Cat. No. HKTX1MAG-38K)
KIM-1
Osteopontin
Renin
TFF-3
Human Kidney Toxicity Panel 2Serum samples(Cat. No. HKTX2MAG-38K)
β-2-Microglobulin
Clusterin
Cystatin C
Human Kidney Toxicity Panel 3Urine samples(Cat. No. HKTX3MAG-38K)
KIM-1
Renin
TFF-3
Human Kidney Toxicity Panel 4Urine samples(Cat. No. HKTX4MAG-38K)
Albumin
β-2-Microglobulin
Clusterin
Cystatin C
Osteopontin
Rat Kidney Toxicity Panel 1 (Cat. No. RKTX1MAG-37K)
Calbindin
Clusterin
GSTaIP-10
KIM-1
Osteopontin
TIMP-1
VEGF
For Research Use Only. N
EURO
SCIEN
CE / TO
XIC
ITY
Rat Kidney Toxicity Panel 2 (Cat. No. RKTX2MAG-37K)
AGP
Albumin
β-2-Microglobulin
Cystatin C
EGF
Lipocalin-2/NGAL
Rat Kidney Toxicity Panel 1 (Cat. No. RKTX1-37K)
Clusterin
KIM-1
Osteopontin
Rat Kidney Toxicity Panel 2 (Cat. No. RKTX2-37K)
Albumin
β-2-Microglobulin
Cystatin C
Single Plex Toxicity Kitsa-2-Microglobulin (Rat)*
Canine Kidney Toxicity Panel 1Urine Samples(Cat. No. CKTX1MAG-97K) NEW!
Clusterin
Cystatin C
KIM-1
Canine Kidney Toxicity Panel 2MB Format Coming Soon*
Albumin
Osteopontin
Rat Vascular Injury Panel 1 MB Format Coming Soon*
Caveolin-1
CINC-1/GRO
CTGF
MCP-1
PAI-1
TIMP-1
sVCAM-1
VEGF
von Willebrand Factor
Rat / Mouse Neuropeptide n
MB Format Coming Soon*
a-MSH
β-Endorphin
Neurotensin
Orexin A
Oxytocin
Substance P
12
For R
esea
rch
Use
Only
.Inflammation / ImmunologyHuman Cytokine / Chemokine Panel I(Cat. No. MPXHCYTO-60K) (Cat. No. HCYTOMAG-60K)
(Cat. No. HCYTMAG-60K-PX29) 29 Cat. No. HCYTMAG-60K-PX30 • 30 (Cat. No. HCYTMAG-60K-PX38) 38 (Cat. No. HCYTMAG-60K-PX41) 41
EGF •
Eotaxin •
FGF-2
Flt3 ligand
Fractalkine
G-CSF •
GM-CSF •
GRO
IFNa2 •
IFNγ •IL-1a •IL-1β •IL-1ra •
IL-2 •
IL-3 •
IL-4 •
IL-5 •
IL-6 •
IL-7 •
IL-8 •
IL-9
IL-10 •
IL-12 (p40) •
IL-12 (p70) •
IL-13 •
IL-15 •
IL-17A •
IP-10 •
MCP-1/CCL2 •
MCP-3/CCL7
MDC/CCL22
MIP-1a •MIP-1β •PDGF-AA†
PDGF-AB/BB†
RANTES† •
sCD40L
TGFaTNFa •TNFβ •VEGF •
Human Cytokine / Chemokine Panel II(Cat. No. MPXHCYP2-62K) **(Cat. No. HCYP2MAG-62K) (Cat. No. HCP2MAG-62K-PX23) 23
6Ckine/CCL21
BCA-1/CXCL13
CTACK/CCL27
ENA-78/CXCL5
Eotaxin-2/CCL24/MPIF-2
Eotaxin-3/CCL26
IL-16
IL-20
IL-21
IL-23
IL-28A
IL-33/NF-HEV (mature)
I-309/CCL1
LIF
MCP-2
MCP-4
MIP-1d (MIP-5/CCL15)
SCF
SDF-1a+β/CXCL12
TARC/CCL17
TPO
TRAIL/TNFSF10
TSLP
Human Cytokine / Chemokine Panel III(Cat. No. MPXHCYP3-63K) **(Cat. No. HCYP3MAG-63K)
HCC-1/CCL14a†
IL-11
IL-29/IFNγ2
I-TAC/CXCL11
LIX/CXCL6/GCP-2
Lymphotactin
M-CSF
MIG/CXCL9
MIP-3a/CCL20
MIP-3β/CCL19
NAP-2/CXCL7†
Human High Sensitivity Cytokine / Chemokine(Cat. No. HSCYTO-60SK) (Cat. No. HSCYTMAG-60SK) (Cat. No. HSCYMAG60SPMX13) 13
GM-CSF
IL-1βIL-2
IL-4
IL-5
IL-6
IL-7
IL-8
IL-10
IL-12 (p70)
IL-13
IFNγTNFa
Human Soluble Cytokine Receptor(Cat. No. HSCR-32K) MB Format Coming Soon*
sCD30
sEGFR
sgp130
sIL-1RI
sIL-1RII
sIL-2RasIL-4R
sIL-6R
sRAGE
sTNF RI
sTNF RII
sVEGF R1
sVEGF R2
sVEGF R3
Human Th17(Cat. No. HTH17MAG-14K) (Cat. No. HT17MG-14K-PX25) NEW! 25
GM-CSF
IFNγIL-1βIL-2
IL-4
IL-5
IL-6
IL-9
IL-10
IL-12 (p70)
IL-13
IL-15
IL-17A
IL-17E/IL-25
IL-17F
IL-21
IL-22
IL-23
IL-27
IL-28A
IL-31
IL-33
MIP-3aTNFaTNFβ
* Coming Soon
** Discontinued non-magnetic bead format December 31, 2012
† Cannot be plexed together: 1) PDGF-AA. PDGF-AB/BB and RANTES 2) HCC-1/CCL14a and NAP-2/CXCL7
• Analytes In HCYTMAG-60K-PX30
♦ Analytes In MCYTOMAG-70K-PMX
Non-magnetic bead format
INFL
AM
MA
TIO
N /
IM
MU
NO
LOG
Y
13
For Research Use Only.
Mouse Cytokine / Chemokine Panel III(Cat. No. MCYP3MAG-74K)
IL-20
IL-23
IL-27
IL-33
MDC
TIMP-1
Mouse Soluble Cytokine Receptor(Cat. No. MSCR-42K) **(Cat. No. MSCRMAG-42K) NEW!
sCD30
sgp130
sIL-1RI
sIL-1RII
sIL-2RasIL-4R
sIL-6R
sRAGE
sTNF RI
sTNF RII
sVEGF R1
sVEGF R2
sVEGF R3
Mouse Th17 (Cat. No. MTH17MAG-47K)(Cat. No. MT17MAG47K-PX25) 25
GM-CSF
IFNγIL-1βIL-2
IL-4
IL-5
IL-6
IL-10
IL-12 (p70)
IL-13
IL-15
IL-17A
IL-17E/IL-25
IL-17F
IL-21
IL-22
IL-23
IL-27
IL-28A
IL-28B
IL-31
IL-33
MIP-3aTNFaTNFβ
Human TIMP 1Serum samples(Cat. No. HTMP1MAG-54K)
TIMP-1
TIMP-2
Human TIMP 2Cell culture samples(Cat. No. HTMP2MAG-54K)
TIMP-1
TIMP-2
TIMP-3
TIMP-4
Non-Human Primate Cytokine/Chemokine(Cat. No. MPXPRCYTO-40K) (Cat. No. PRCYTOMAG-40K) (Cat. No. PCYTMG-40K-PX23) 23
G-CSF
GM-CSF
IL-1βIL-1ra
IL-2
IL-4
IL-5
IL-6
IL-8
IL-10
IL-12/23 (p40)
IL-13
IL-15
IL-17A
IL-18
IFNγMCP-1/CCL2/MCAF
MIP-1aMIP-1βsCD40L
TGFaTNFaVEGF
Mouse Cytokine / Chemokine Panel I (Cat. No. MPXMCYTO-70K) (Cat. No. MCYTOMAG-70K)(Cat. No. MCYTOMAG-70K-PMX) ♦ 25
(Cat. No. MCYTMAG-70K-PX32) 32
Eotaxin
G-CSF ♦GM-CSF ♦IFNγ ♦IL-1a ♦IL-1β ♦IL-2 ♦
IL-3
IL-4 ♦
IL-5 ♦
IL-6 ♦
IL-7 ♦
IL-9 ♦
IL-10 ♦
IL-12 (p40) ♦
IL-12 (p70) ♦
IL-13 ♦IL-15 ♦
IL-17A ♦
IP-10 ♦KC ♦LIF
LIX
MCP-1/CCL2 ♦M-CSF
MIG
MIP-1a ♦MIP-1β ♦MIP-2 ♦RANTES ♦TNFa ♦
Mouse Cytokine / Chemokine Panel II(Cat. No. MCYP2MAG-73K)
EPO
Exodus-2
Fractalkine
IL-16
IL-21
IL-22
IL-17E/IL-25
IL-28B
MCP-5
MIP-3aMIP-3βTARC
Human CD8+ T CellMB Format Coming Soon*
sCD137
sFas
sFasL
GM-CSF
Granzyme A
Granzyme B
IFNγIL-2
IL-4
IL-5
IL-6
IL-10
IL-13
MIP-1aMIP-1βPerforin
TNFa
Human MMP 1(Cat. No. HMMP1-55K) MB Format Coming Soon*
MMP-3
MMP-12
MMP-13
Human MMP 2(Cat. No. HMMP2-55K) (Cat. No. HMMP2MAG-55K)
MMP-1
MMP-2
MMP-7
MMP-9
MMP-10
INFLA
MM
ATIO
N / IM
MU
NO
LOG
Y
Mouse CD8+ T Cell (Cat. No. MCD8MAG-48K)(Cat. No. MCD8MAG48K-PX15) 15
sCD137
sFas
sFasL
GM-CSF
Granzyme B
IFNγIL-2
IL-4
IL-5
IL-6
IL-10
IL-13
MIP-1βRANTES
TNFa
14
For R
esea
rch
Use
Only
.
See our website for Single Plex Kit catalogue numbers.
Inflammation / Immunology, continued Immune ResponseHuman Immunoglobulin Isotyping(Cat. No. HGAMMAG-301K)
IgAIgG1 IgG2
IgG3 IgG4IgM
Mouse Immunoglobulin Isotyping(Cat. No. MGAMMAG-300K)
IgAIgG1 IgG2a
IgG2b IgG3IgM
Rat Immunoglobulin Isotyping(Cat. No. RGAMMAG-302K)
IgG1IgG2aIgG2bIgG2c
IgAIgEIgM
Single Plex IgEIgE (Human) IgE (Mouse)
HGMAMAG-303EMIGEMAG-300K-01
Human Sepsis Panel 1(Cat. No. HSP1MAG-63K)
MIF PAI-1 (total) sFas
sFasLsICAM-1sVCAM-1
Human Sepsis Panel 2 (Cat. No. HSP2MAG-63K)
Granzyme BHSP70IL-1aIL-8
MIP-1aMIP-1βMMP-8
Human Sepsis Panel 3 (Cat. No. HSP3MAG-63K)
Lactotransferrin (LTF)Lipocalin-1Neutrophil Elastase-2 (ELA2)ResistinThrombospondin-1 (TSP-1)
Human Skin(Cat. No. SKIN-50K) MB Format Coming Soon*
Cortisol
Fibronectin
Human Serum Albumin (HSA)
Involucrin
Keratin-6
Keratin-1,10
LPS * Coming Soon
▼ Panel Premix Only
Non-magnetic bead format
Rat Cytokine / Chemokine(Cat. No. RECYTMAG-65K)(Cat. No. RECYMAG65K27PMX) 27
EGF Eotaxin Fractalkine G-CSF GM-CSF GRO-KC IFNγ IL-1a IL-1β IL-2IL-4 IL-5 IL-6IL-10
IL-12 (p70) IL-13 IL-17A IL-18 IP-10 Leptin LIX MCP-1 MIP-1a MIP-2 RANTES TNFa VEGF
Canine Cytokine / Chemokine(Cat. No. CCYTOMAG-90K) (Cat. No. CCYTMG-90K-PX13) 13
GM-CSFIFNγIL-2 IL-6 IL-7 IL-8 IL-10
IL-15IL-18IP-10KC-likeMCP-1/CCL2/MCAFTNFa
INFL
AM
MA
TIO
N /
IM
MU
NO
LOG
Y /
IMM
UN
E R
ESPO
NSE
Mouse MMP Panel 1Serum/plasma Samples MB Format Coming Soon*
MMP-2
MMP-3
MMP-8
Mouse MMP Panel 2Serum/plasma Samples MB Format Coming Soon*
MMP-9 MMP-12
Mouse MMP Panel 3Cell culture samples MB Format Coming Soon*
MMP-2
MMP-3
MMP-8
MMP-9
MMP-12
Porcine Cytokine / Chemokine(Cat. No. PCYTMAG-23K) NEW!
(Cat. No. PCYTMG-23K-13PX) NEW! 13
GM-CSFIFNγIL-1aIL-1raIL-1βIL-2IL-4
IL-6IL-8IL-10IL-12IL-18TNFa
Multi-species TGFβ - 1 plex(Cat. No. TGFB-64K-01) MB Format Coming Soon*
TGFβ1
Multi-species TGFβ - 3 plex ▼(Cat. No. TGFB-64K-03) MB Format Coming Soon*
TGFβ1
TGFβ2
TGFβ3
15
Cell Signaling & Phosphoprotein DetectionNew Challenges, Faster Answers
Multiplexing, using the Luminex® xMAP® platform, provides faster answers to cell signaling questions compared to traditional Western blots, mass spectrometry analysis, and radioactive phosphorylation assays that require large amounts of sample.
Now available are three MILLIPLEX® map cell signaling portfolios based on the Luminex®
xMAP® platform.
• MILLIPLEX® map Cellular Metabolism Assays
• MILLIPLEX® map Stem Cell Assays
• MILLIPLEX® map Cell Signaling Assays
Cellular Metabolism AssaysOur MILLIPLEX® map Cellular Metabolism Panels will enable you to:
• Measure analytes within the panels in small sample sizes of cell lysate or tissue extract
• Examine intracellular pathways regulating cellular metabolism and energy production
• Facilitate research areas such as mitochondrial dysfunction and toxicity, metabolic disorders, neurological disorders, cancer and aging
emdmillipore.com/analytes_q4
Stem Cell AssaysOur MILLIPLEX® map Stem Cell biomarker assays enable you to characterize your ES cells, iPS cells, or even your cancer cells using the Luminex® xMAP® platform. Our upcoming panels are of interest to many areas of research, including development and oncology.
MILLIPLEX® map Cell Signaling AssaysOur cell signaling kits and MAPmates™ offer you the ability to:
• Measure multiple total or phosphorylated proteins along a signaling pathway, in a single sample
• Simultaneously measure sites in multiple pathways
• Conduct all necessary measurements using minimal sample volume
• Choose from analytically validated kits or design your custom assay with our MAPmates™
For Research Use Only.
MILLIPLEX
® ma
p C
ELL SIGN
ALIN
G
16
For R
esea
rch
Use
Only
.
Cell Signaling
Stem Cell Assays
Cellular Metabolism AssaysHuman Drug Metabolism(Cat. No. HDMMAG-19K)
ALDH4A1
CES1
EPHX1
MAO-A
MAO-B
Human Stem Cell Pluripotency Panel 1 ▼(Cat. No. 48-617MAG) NEW!
c-Myc
Nanog
Oct 3/4
Sox2
Multi-species Pyruvate Dehydrogenase (PDH) Complex ▼
(Cat. No. PDHMAG-13K)
Analyte Total Phosphorylated
PDH 3
PDH 3 (Ser232)
PDH 3 (Ser293)
PDH 3 (Ser300)
Human Fatty Acid Oxidation Panel 1 (Cat. No. HFA01MAG-11K)
Acetyl-CoA acyltransferase 2 (ACAA2)
Peroxisomal bifunctional enzyme (LPBE/ECHD)
Short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD)
Mitochondrial trifunctional protein (TFP)
Human Fatty Acid Oxidation Panel 2 (Cat. No. HFA02MAG-11K)
Carnitine palmitoyltransferase 2 (CPT2)
2,4-dienoyl-CoA reductase (DECR1)
Electron transfer flavoprotein, mitochondrial (ETF)
Medium-chain acyl-CoA dehydrogenase (MCAD)
Peroxisomal multifunctional enzyme 2 (MFE2)
Human Oxidative Phosphorylation ▼(Cat. No. H0XPSMAG-16K)
Complex I (NADH-Ubiquinone Oxidoreductase)
Complex II (Succinate Ubiquinone Oxidoreductase)
Complex III (Ubiquinone Cytochrome C Oxidoreductase)
Complex IV (Cytochrome C Oxidase)
Complex V (ATP Synthase)
NNT (Nicotinamide Nucleotide Transhydrogenase)
Rat/Mouse Oxidative Phosphorylation ▼
(Cat. No. RM0XPSMAG-17K)Complex I (NADH-Ubiquinone Oxidoreductase)
Complex III (Ubiquinone Cytochrome C Oxidoreductase)
Complex V (ATP Synthase)
Human Oxidative Stress ▼(Cat. No. H0XSTMAG-18K)Catalase
PRX2 (PRDX2)
SOD1
SOD2
TRX1
MIL
LIPL
EX®
ma
p C
ELL
SIG
NA
LIN
G
CEL
LULA
R M
ETA
BOLI
SM /
STE
M C
ELL
See our website for species cross-reactivity.
Akt / mTOR — 11 Plex(Cat. No. 48-611MAG) ▼
Analyte Total Phosphorylated
Akt 3 (Ser473)
GSK3a 3 (Ser21)
GSK3β 3 (Ser9)
IGF1R 3 (Tyr1135/1136)
IR 3 (Tyr1162/1163)
IRS1 3 (Ser312)
mTOR 3 (Ser2448)
p70 S6 Kinase 3 (Thr412)
PTEN 3 (Ser380)
RPS6 3 (Ser235/236)
TSC2 3 (Ser939)
Human Stem Cell Pluripotency Panel 2 ▼MB Format Coming Soon*
E-cadherin
EpCam
KLF4
LIN-28
SSEA1
TRA-1-60
TRA-1-80
17
For Research Use Only.C
ELL SIGN
ALIN
G
Early Apoptosis — 7 Plex(Cat. No. 48-669MAG) ▼ NEW!
Analyte Total Phosphorylated
Akt 3 (Ser473)
BAD 3 (Ser112)
Bcl-2 3 (Ser70)
Active Caspase 8 3
Active Caspase 9 3
JNK 3 (Thr183/Tyr185)
p53 3 (Ser46)
Human Late Apoptosis — 3 Plex(Cat. No. 48-670) **(Cat. No. 48-670MAG) ▼ NEW!
Analyte Total Phosphorylated
Active Caspase 3 3
Cleaved PARP 3
GAPDH 3
Total Akt / mTOR — 11 Plex(Cat. No. 48-612MAG) ▼
Analyte Total Phosphorylated
Akt 3
GSK3a 3
GSK3β 3
IGF1R 3
IR 3
IRS1 3
mTOR 3
p70S6 Kinase 3
PTEN 3
RPS6 3
TSC2 3
Human Angiogenesis RTK — 10 Plex(Cat. No. 48-674MAG) ▼
Analyte Total Phosphorylated
c-Kit 3 (pan Tyr)
Flt3 3 (pan Tyr)
M-CSFR 3 (pan Tyr)
PDGFRa 3 (pan Tyr)
PDGFRβ 3 (pan Tyr)
Tie1 3 (pan Tyr)
Tie2 3 (pan Tyr)
VEGF R1 3 (pan Tyr)
VEGF R2 3 (pan Tyr)
VEGF R3 3 (pan Tyr)
Human Total Angiogenesis RTK — 10 Plex(Cat. No. 48-673MAG) ▼
Analyte Total Phosphorylated
c-Kit 3
Flt3 3
M-CSFR 3
PDGFRa 3
PDGFRβ 3
Tie1 3
Tie2 3
VEGF R1 3
VEGF R2 3
VEGF R3 3
Human EGFR Profiler — 8 Plex(Cat. No. 48-613MAG) ▼
Analyte Total Phosphorylated
EGFR 3
EGFR 3 (Thr654)
EGFR 3 (Thr669)
EGFR 3 (Tyr845)
EGFR 3 (Tyr1045)
EGFR 3 (Ser1047)
EGFR 3 (Tyr1068)
EGFR 3 (Tyr1086)
Human Heat Shock Protein — 5 Plex(Cat. No. 48-615MAG) ▼
Analyte Total Phosphorylated
HSP27 3
Phospho-HSP27 3 (Ser78/Ser82)
HSP60 3
HSP70 3
HSP90a 3
* Coming Soon
▼ Panel Only Premix
** Discontinued non-magnetic bead format December 31, 2012
Non-magnetic bead format
18
For R
esea
rch
Use
Only
.
See our website for cross reactivity.
Src Family Kinase — 8 Plex(Cat. No. 48-650) ** ▼
Analyte Total Phosphorylated
Blk 3 (pan Tyr)
Fgr 3 (pan Tyr)
Fyn 3 (pan Tyr)
Hck 3 (pan Tyr)
Lck 3 (pan Tyr)
Lyn 3 (pan Tyr)
Src 3 (pan Tyr)
Yes 3 (pan Tyr)
Src Family Kinase Active Site — 8 Plex(Cat. No. 48-650MAG) ▼ NEW!
Analyte Total Phosphorylated
Blk 3 (Tyr389)
Fgr 3 (Tyr412)
Fyn 3 (Tyr420)
Hck 3 (Tyr411)
Lck 3 (Tyr394)
Src 3 (Tyr419)
Yes 3 (Tyr421)
CEL
L SI
GN
ALI
NG
STAT — 5 Plex(Cat. No. 48-610) ** ▼
(Cat. No. 48-610MAG) ▼
Analyte Total Phosphorylated
STAT1 3 (Tyr701)
STAT2 3 (Tyr690)
STAT3 3 (Tyr705)
STAT5A/B 3 (Tyr694/699)
STAT6 3 (Tyr641)
Cell Signaling, continued
Multi-Pathway — 9 Plex(Cat. No. 48-680MAG) ▼
Analyte Total Phosphorylated
Akt 3 (Ser473)
CREB 3 (Ser133)
Erk/MAPK 1/2 3 (Thr185/Tyr187)
NFkB 3 (Ser536)
JNK 3 (Thr183/Tyr185)
p38 3 (Thr180/Tyr182)
p70 S6 Kinase 3 (Thr412)
STAT3 3 (Ser727)
STAT5A/B 3 (Tyr694/699)
T-Cell Receptor — 7 Plex(Cat. No. 48-690) ** ▼
(Cat. No. 48-690MAG) NEW!
Analyte Total Phosphorylated
CD3e 3 (pan Tyr)
CREB 3 (Ser133)
Erk/MAPK 1/2 3 (Thr185/Tyr187)
LAT 3 (pan Tyr)
Lck 3 (pan Tyr)
Syk 3 (pan Tyr)
ZAP-70 3 (pan Tyr)
Human Total Mitogenesis RTK — 7 Plex(Cat. No. 48-671MAG) ▼
Analyte Total Phosphorylated
cMet/HGFR 3
EGFR 3
ErbB2/HER2 3
ErbB3 3
ErbB4 3
IGF1R 3
IR 3
Human Mitogenesis RTK — 7 Plex(Cat. No. 48-672MAG) ▼
Analyte Total Phosphorylated
cMet/HGFR 3 pan Tyr
EGFR 3 pan Tyr
ErbB2/HER2 3 pan Tyr
ErbB3 3 pan Tyr
ErbB4 3 pan Tyr
IGF1R 3 pan Tyr
IR 3 pan Tyr
MAPK / SAPK — 10 Plex(Cat. No. 48-660) ** ▼
(Cat. No. 48-660MAG) ▼ NEW!
Analyte Total Phosphorylated
ATF2 3 (Thr71)
ErK/MAPK 1/2 3 (Thr185/Tyr187)
HSP27 3 (Ser78)
JNK 3 (Thr183/Tyr185)
c-Jun 3 (Ser73)
MEK1 3 (Ser222)
MSK1 3 (Ser212)
p38 (SAPK2A/B) 3 (Thr180/Tyr182)
p53 3 (Ser15)
STAT1 3 (Tyr707)
19
For Research Use Only.C
ELL SIGN
ALIN
G
TGFβ — 6 Plex(Cat. No. 48-614MAG) ▼
Analyte Total Phosphorylated
Akt 3 (Ser473)
Erk 3 (Thr185/Tyr187)
SMAD2 3 (Ser465/467)
SMAD3 3 (Ser423/425)
SMAD4 3
TGFβRII 3
* Coming Soon
▼ Panel Only Premix
** Discontinued non-magnetic bead format December 31, 2012
Non-magnetic bead format
Akt — 2 Plex(Cat. No. 48-618MAG) ▼ MB Format Coming Soon* NEW!
Analyte Total Phosphorylated
Akt 3
Akt 3 (Ser473)
Erk / MAPK 1/2 — 2 Plex(Cat. No. 48-619MAG) ▼ MB Format Coming Soon* NEW!
Analyte Total Phosphorylated
Erk 3
Erk 3 (Thr185/Tyr187)
Lysates
Analyte Cat. No. Analyte Cat. No.
A431: EGF 47-210 HEPG2: TGFβ2 47-235
A549:camptothecin 47-218 HFF-1: 10% Serum 47-237
Daudi: IL-4 47-217 HUVEC: 10% Serum
47-238
Hek293: 10% Serum 47-233 Jurkat: anisomycin 47-207
HEK293: IGF-1 47-228 Jurkat: paclitaxel 47-220
HeLa: HGF 47-222 Jurkat: unstim 47-206
HeLa: IFNa 47-226 Jurkat:H2O2 47-208
HeLa: Lambdaphos-phatase
47-229 Kasumi-3:SCF 47-214
HeLa: PVD 47-223 MCF7:IGF-1 47-216
HeLa: TNFa 47-212 NIG3T3: PDGF-AB 47-213
HeLa: TNFaβ+CalA 47-230 NIH3T3: anisomycin
47-219
HeLa: unstim 47-205 NIH3T3: unstim 47-221
HeLa:HS/Ars 47-211 Ramos: PVD 47-224
HepG2: Insulin 47-227 THP-1: 10% Serum 47-236
20
* Coming Soon For R
esea
rch
Use
Only
.MAPmates™ Cell Signaling Single-plex Kits
The following MAPmates™ should not be plexed together:
• MAPmates™ that require a different assay buffer
• Phosphospecific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
• Pan Tyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and HSP27 (Ser78)
• More than 1 phospho-MAPmate™ for a single target (Akt, STAT3, p53, Src, Rb)
• GAPDH and β-Tubulin can not be plexed with kits or MAPmates™ containing panTyr
Buffer & Detection Kit (Cat. No. 48-602)Required to run all MAPmate™ assays.
Analyte Total Phosphorylated
GAPDH (Human) 46-667
Akt/PKB (assay buffer 1) 46-605 (Ser473) 46-601
Akt/PKB (assay buffer 1) (Thr308) 46-645
Akt/PKB (assay buffer 2) 46-675 (Ser473) 46-677
ATF2 (Thr71) 46-658
BAD 46-695 (Ser112) 46-694
Active Caspase 3 46-604
CREB 46-632 (Ser133) 46-631
EGF Receptor 46-606 (Pan Tyr) 46-603
Erk/MAPK 1/2 46-609 (Thr185/Tyr187) 46-602
GSK3β 46-689 (Ser9) 46-690
H2A.X (Ser139) 46-692
HIF-1a 46-665
HSP27 46-608 (Ser78) 46-607
IGF1 Receptor 46-646 (Pan Tyr) 46-647
IkBa 46-644 (Ser32) 46-643
Insulin Receptor (IR) 46-687 (Tyr1162/1163) 46-688
IRS1 46-628 (Pan Tyr) 46-627
JNK/SAPK1 46-618 (Thr183/Tyr185) 46-613
c-Jun (Ser73) 46-622
c-Kit 46-620 (Pan Tyr) 46-619
Lck (Pan Tyr) 46-616
Lck (Tyr394) 46-712
Lyn 46-707 (Tyr397) 46-708
c-Met/HGFR 46-650 (Pan Tyr) 46-651
MEK1 46-669 (Ser222) 46-670
mTOR 46-685 (Ser2448) 48-686
NFkB 46-701 (Ser536) 46-702
p21 46-621
p38 (SAPK2A/B) 46-612 (Thr180/Tyr182) 46-610
Analyte Total Phosphorylated
p53 46-662 (Ser15) 46-663
p53 (Ser46) 46-664
p70 S6 Kinase 46-630 (Thr412) 46-629
Cleaved PARP 46-656
PRAS40 46-680 (Thr246) 46-681
PTEN 46-678 (Ser380) 46-679
Rb 46-703 (Thr252) 46-704
Rb (Ser811) 46-706
Rb (Thr826) 46-705
Src 46-709 (Tyr419) 46-710
Src (Tyr530) 46-711
STAT1 46-654 (Tyr701) 46-655
STAT2 (Tyr690) 46-635
STAT3 46-625 (Tyr705) 46-623
STAT3 (Ser727) 46-624
STAT5A/B (Tyr694/699) 46-641
ZAP-70 (Pan Tyr) 46-661
Analyte Total Phosphorylated
GAPDH (Human) 46-667MAG
β-Tubulin (Human/Rat/Mouse)
46-713MAG
Akt/PKB (assay buffer 2) * (Ser473) *
Active Caspase 3 *
CREB *
EGF Receptor * (Pan Tyr) *
Erk/MAPK 1/2 * (Thr185/Tyr187) *
GSK3b * (Ser9) *
IkBa * (Ser32) *
JNK/SAPK1 * (Thr183/Tyr185) *
c-Jun (Ser73) *
c-Kit * (Pan Tyr) *
MEK1 * (Ser222) *
c-Met/HGFR * (Pan Tyr) *
mTOR * (Ser2448) *
p21 *
p38 (SAPK2A/B) * (Thr180/Tyr182) *
p70S6K * (Thr412) *
RPS6 * (Ser235/236) *
STAT1 * (Tyr701) *
STAT3 * (Tyr705) *
STAT3 (Ser272) *
STAT5A/B (Tyr694/699) *
Tie2 * (Pan Tyr) *
VEGFR2 * (Pan Tyr) *
Magnetic Bead Format
MA
Pmat
es™
21
For Research Use Only.
Luminex® FLEXMAP 3D® System(Cat. No. 40-014 - FLEXMAP 3D®) (Cat. No. 40-022 - FLEXMAP 3D® with MILLIPLEX® Analyst Software)
The FLEXMAP 3D® system combines differentially dyed
fluorescent microsphere sets with an innovative instrument
design that can accommodate measuring the concentrations
of up to 500 unique analytes within a single sample rapidly
and precisely. Features—such as automated probe height
adjustment, simplified routine maintenance operations and
an intuitive software interface—make
FLEXMAP 3D® a flexible and easy-to-use
multiplexing system.
Luminex® xMAP® Technology
MAGPIX® System(Cat. No. 40-072 - MAGPIX®) (Cat. No. 40-073 - MAGPIX® with MILLIPLEX® Analyst Software)
Combined with our MILLIPLEX® MAP magnetic bead-based
multi-analyte panels, analysis software and technical
support, the new Luminex® MAGPIX® system provides a
complete solution for rapid, accurate biomarker quantitation
in a variety of sample matrices. This affordable system can
perform up to 50 tests simultaneously in a single reaction
volume, greatly reducing sample input, reagents and labor
while improving productivity. The MAGPIX® system features
an innovative design based on CCD imaging technology that
enables for a more compact, robust system. In addition, it is
easy to operate and maintain with streamlined start-up and
shutdown protocols and minimal maintenance requirements.
Luminex® 200™ System(Cat No. 40-012- MILLIPLEX® Analyzer) (Cat No. 40-013 - MILLIPLEX® Analyzer with MILLIPLEX® Analyst Software)
MILLIPLEX® Analyzer, the Luminex® 200™ System, is
a compact lab analysis system that integrates lasers,
optics, fluidics, a controller, advanced digital signal
processing, an XY Platform, the newest version
analysis software, and a PC with monitor. Specifically
designed to enhance the use of xMAP® technology,
this system enables simultaneous assays of up to
100 analytes per well of a microtiter plate. Key
features include: flexible data analysis package, user
friendly functions, flexible assay design features, bar
code reader for enhanced efficiency and multiple
formats for generating
data reports.
LUM
INEX
® TECH
NO
LOG
YAs a Luminex® partner, EMD Millipore is a distributor of Luminex® instruments, accessories and software. We were
there at the beginning to help validate Luminex® as a standard of multiplexing, and our ongoing dedication and
experience in this technology enable you to gain more information faster, without compromising reliability. Visit our
website at www.emdmillipore.com/luminex for more information on the following technologies:
INSTRU
MEN
TS&
SOFTW
AR
E
22
MILLIPLEX® Analyst Software
emdmillipore.com/analytes_q4
A new level of data analysis to help you do your best work! EMD Millipore combines the streamlined data acquisition
power of xPONENT® software with sophisticated analysis
capabilities of the new MILLIPLEX® Analyst 5.1, enabling
you to manage, track and analyze your
multiplex assays fast and efficiently.
Data acquisition and analysis integrates
seamlessly with all Luminex® instruments,
including MAGPIX®, Luminex® 200™ and
FLEXMAP 3D® systems. MILLIPLEX® Analyst 5.1
is available as one- and five-seat licenses,
enabling complete flexibility for small, medium
and large laboratories. You can easily create
reports in multiple formats for
enhanced presentations.
MILLIPLEX® Analyst 5.1 software offers simple integration with Luminex® xPONENT® System:
• Seamless importing of CSV or Excel® files
• User-friendly plate setup for flexibility and efficiency
• Calculate large data sets in seconds
• Superior algorithms yield better data at the low and
high ends of the standard curve
• Flexible report formats and enhanced presentation
features
For R
esea
rch
Use
Only
.M
ILLI
PLEX
® A
NA
LYST
SO
FTW
AR
E
MILLIPLEX® Analyst 5.1(Cat. No. 40-082 MILLIPLEX® Analyst 5.1 - upgrade (for 3.5 users)) (Cat. No. 40-086 MILLIPLEX® Analyst 5.1 – 1 seat license) (Cat. No. 40-087 MILLIPLEX® Analyst 5.1 – 5 seat license) (Cat. No. 40-088 MILLIPLEX® Analyst 5.1 – database, 1 seat license) (Cat. No. 40-089 MILLIPLEX® Analyst 5.1 – database, 5 seat license)
INST
RUM
ENTS
& S
OFT
WA
RE
23
New features of MILLIPLEX® Analyst 5.1 software:
• Complete with CD and Dongle (USB/Thumb drive) for quick and easy download
• Auto-detect data features for standards, quality controls and samples
• Increased high-end standard value capabilities
• The best curve fit possible (using gold standard algorithms)
• Multiple Quality Control values (up to 5)
• Curve Potency feature (comparing two standard curves)
• Reports values for CHI and CVs
• Complete quantitative and qualitative analysis for improved flexibility
• 21CFR part 11 available option
• Automatic download on 32 or 64 bit computers
• Optional database package available late 2012—MILLIPLEX Analyst 5.1 PLUS
• Easy Integration:
— Export compatible—PDF and Microsoft Excel® formats
— Compatible with all Luminex® 1.7 file formats
— Import data from Microsoft Excel®, Bio-Plex® (.txt), Miraibio™ (.txt), and other
Luminex® software programs
Better Curve Fit (High R2)Analyte CHI CV R2 MinDC MaxDC
GM-CSF 6.80% 1.15% 0.999 0.42 5431
IFNγ 6.31% 0.84% 0.999 0.35 6189
IL-1B 10.04% 1.23% 0.998 0.41 8441
IL-2 7.66% 2.84% 0.999 0.32 7796
IL-4 1.23% 0.20% 1 0.32 8711
IL-5 11.67% 1.18% 0.998 0.42 5417
Il-6 16.48% 1.71% 0.996 0.42 7494
TNFa 8.71% 1.01% 0.999 0.36 7207
Among many improved features available with MILLIPLEX® Analyst 5.1 software is 5PL weighted curve fit, enabling superior curve fit (R2 above 0.995) at both extremes of typical standard curves.
For Research Use Only.M
ILLIPLEX® A
NA
LYST SOFTW
AR
E
24
For R
esea
rch
Use
Only
.
NEW! ELx405TSRSML and Elx405LSRML Microplate Washer For 96-Well Biomagnetic Separation(Cat. No. 40-094 BioTek® 96-well Magnetic Washer) (Cat. No. 40-095 BioTek® 96-well Magnetic/Vacuum Filtration Washer) (Cat. No. 40-096 BioTek® 96-well Magnetic Washer with Touch Screen and Ultrasound) (Cat. No. 40-097 BioTek® 96-well Magnetic /Vacuum Filtration Washer with Touch Screen and Ultrasound)
In partnership with BioTek® we now offer the newest ELx405
enhancement: full plate biomagnetic separation, washing and
vacuum filtration system for magnetic bead assays. Both systems
offer magnetic and filtration washing options—with the TS model
now offering touch screen and ultra-sound capabilities.
BioTek® Washer Advantages:
• Touch screen, high resolution LED backlit user interface screen
• Magnetic bead washing—Luminex® xMAP® approved
• Fast and efficient vacuum filtration
• Optional software package
• Built-in Ultrasonic Advantage™ cleaner
For R
esea
rch
Use
Only
.
Handheld Magnetic Separator Block for 96-Well Flat Bottom Plates or 96-Well Conical Well Plates(Cat. No. 40-285)
The Handheld Magnetic Separator Block offers a low cost option
for biomagnetic separation. Magnets are positioned around the
bottom of the well to pull the beads to the side of the well. The
top magnetic frame is white polycarbonate, with a corrosion
resistant steel plate underneath, all mounted to a polypropylene
base. An adjustable clip system holds a wide variety of
microplates to the separator block, and an O-Ring on the base
plate facilitates gripping.
WA
SHIN
G S
OLU
TIO
NS Magnetic Bead Kit
Washing Solutions
25
Discontinued Non-MagneticCatalogue No.
Kit DescriptionNon-Magnetic Bead Panel
Replacement Magnetic Bead Catalogue No.
Kit DescriptionMagnetic Bead Panel
48-650 Src Family Kinase - 8 Plex 48-650MAG Src Family Kinase - 8 Plex
48-670 Human Late Apoptosis - 3 Plex 48-670MAG Human Late Apoptosis - 3 Plex
48-610 STAT - 5 Plex 48-610MAG STAT - 5 Plex
48-690 T-Cell Receptor - 7 Plex 48-690MAG T-Cell Receptor - 7 Plex
48-660 MAPK/SAPK - 10 Plex 48-660MAG MAPK/SAPK - 10 Plex
MSCR-42K Mouse Soluble Cytokine Receptor MSCRMAG-42K Mouse Soluble Cytokine Receptor
HNDG1-36K Human Neurodegenerative Disease Panel 1 HNDG1MAG-36K Human Neurodegenerative Disease Magnetic Bead Panel 1
HNDG2-36K Human Neurodegenerative Disease Panel 2 HNDG2MAG-36K Human Neurodegenerative Disease Magnetic Bead Panel 2
HNDG3-36K Human Neurodegenerative Disease Panel 3 HNDG3MAG-36K Human Neurodegenerative Disease Magnetic Bead Panel 3
MPXHCYP2-63K Human Cytokine Panel 2 HCYP2MAG-62K Human Cytokine Panel II
MPXHCYP2PMX23 Human Cytokine Panel 2 HCP2MAG-62K-PX23 Human Cytokine Panel II, 23 Premix
MPXHCYP3-68K Human Cytokine Panel 3 HCYP3MAG-63K Human Cytokine Panel III
MPXHCYP3-PMX9 Human Cytokine Panel 3
MPXHCYP3-PMX11 Human Cytokine Panel 3 HCP3MAG-63K-PX11 Human Cytokine Panel III, 11 Premix
HBN1A-51K Human Bone Panel 1A HBNMAG-51K Human Bone Panel
HBN1B-51K Human Bone Panel 1B HBNMAG-51K Human Bone Panel
As we continue to expand our magnetic bead-based multiplexing portfolio, we
need to do some housekeeping to make room for innovative and unique panels
targeting new species in emerging areas of research. Consequently, we will be
discontinuing some of our non-magnetic bead kits by December 31, 2012*.
Below is a list of soon-to-be discontinued non-magnetic bead panels and the
corresponding replacement magnetic bead panels.
MILLIPLEX® map Magnetic Bead-based Immunoassay KitsAs your research needs broaden, we’re growing with you.
For more information, please contact your local account manager at: www.emdmillipore.com /offices
* Availability of inventory is subject to depletion of existing inventory.
PANEL UPDATES
Magnetic Bead Kit Washing Solutions
Versatility in a Complete Package
To Place an Order or Receive Technical AssistanceIn the U.S. and Canada, call toll-free 1-800-645-5476
For other countries across Europe and the world, please visit: www.emdmillipore.com/offices
For Technical Service, please visit: www.emdmillipore.com/techservice
Get Connected!Join EMD Millipore bioscience on your favorite socialmedia outlet for the latest updates, news, products,innovations and contests!
facebook.com/EMDMilliporeBioscience
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VigeneTech
www.emdmillipore.com/analytes_q4
Dual Detect CELISAs, MILLIPLEX, MultiScreen and OxyELISA are registered trademarks of Merck KGaA, Darmstadt, Germany.EMD Millipore, the M mark, ChemiKine, MAPmates, and SignalProfiler are trademarks of Merck KGaA, Darmstadt, Germany.FLEXMAP 3D, Luminex, MAGPIX, xPONENT, and xMAP are registered trademarks of Luminex Corporation.Luminex 200 is a trademark of Luminex Corporation.Biotek is a registered trademark of BioTek Instruments.Vigene Tech is a trademark of Vigene Tech, Inc.Lit. No. PF1089EN00 Rev. Q 10/2012 MIL-118 SBU-12-06179©2012 EMD Millipore Corporation, Billerica, MA, USA. All Rights Reserved.
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Biomarker AnalysisWith over 25 years of experience and industry leadership in
developing and performing immunoassays on human and
animal specimens, we offer proven bioanalytical services for
biomarkers—from research to clinical trials and beyond.
Learn more at www.emdmillipore.com/cro