Rev. 6th Oct. 2020

✔ enhances the penetration of water-soluble active ingredients into skin.✔ repairs hair damage by enhancing the penetration of water-soluble

active ingredients (ex. water-soluble hydrolyzed keratin) into hair.✔ removes easily waterproof mascara composed with film-forming resin

in cleansing oil.

✔ has an excellent affinity for skin and enhances the moistness of skin.

✔ reduces the stickiness of polyols or oils. Neosolue-Aqulio provides both non-stickiness, non-greasiness and moisture of skin.

✔ substitution with polyols, it can provides both good feeling and moisture of skin.

✔ has no skin irritation and allergic contact dermatitis in human RIPT (Repeated Insult Patch Test).

•R = Ethoxydiglycol residueORRO

O O

＜Results of skin penetration test: photos of epidermal model (cross section) ＞

Enhances penetration of water active ingredients (whitening agents and moisture) into skin.

: aq. solution of 0.001%Fluorescein Sodium+ 2%Neosolue-Aqulio(Blank) : aq. solution of 0.001%Fluorescein Sodium

Amphiphilic Ester

Skin penetration enhancing effect of Neosolue-Aqulio (part1)

Features & Functions

Without Neosolue-AqulioWith Neosolue-Aqulio

After 6 hours After 6 hours

Product Name 성분명 INCI Name IECIC 2014

Neosolue-Aqulio비스-에톡시디글라이콜사이클로헥산1,4-디카복실레이트

BIS-ETHOXYDIGLYCOL CYCLOHEXANE 1,4-DICARBOXYLATE

双-二乙氧基二甘醇环己烷1,4-二羧酸酯

Aqulio-

stratum corneum

epidermal

stratum corneum

epidermal

＊NIPPON FINE CHEMICAL CO., LTD. cannot assume any liability expressed or implied in the presentation of this data nor take any responsibility for patents or the evaluation of finished products. ＊All rights reserved. Please contact us before using product descriptions. The content of this is subject to change without prior notice.＊All statements, technical information and recommendations related to our products are based on information that is reliable, however the accuracy or completeness is not guaranteed.＊Neosolue is a product trade name of NIPPON FINE CHEMICAL CO., LTD.

Rev. 6th Oct. 2020

Neosolue-Aqulio enhances the penetration of active ingredients into hair.

The tensile strength of damaged hair recovers close to healthy hair by treating

water-soluble protein together with Neosolue-Aqulio.

Neosolue-Aqulio is useful for neutral hair coloring.

Neosolue-Aqulio Blank

＜The Hair Penetration Enhancing Effect＞ ＜The Recovery Effect of the Tensile Strength＞

3-O-Ethyl Ascorbic acid（after 3hours）

50

0

100

150

200

250

300

350

Glycine(after 6hours )

Ascolbyl glucoside(after 3hours)

Without Neosolue-Aqulio

With Neosolue-Aqulio

1.7t imes UP

3.3 timesUP

1.4 timesUP

The

Re

lati

ve P

en

etr

atio

n R

atio

(%)

Neosolue-Aqulio enhances the penetration of water-soluble ingredients (Ascorbic acid derivatives and amino acids etc.) into skin.

400＜Results of Penetration Enhancement＞

Skin penetration enhancing effect of Neosolue-Aqulio (part2)

Hair Penetration Enhancing Effect of Neosolue-Aqulio

***P