zirconia – alumina – metal primer. biscos z-prime plus is a single-component priming agent used...

Zirconia – Alumina – Metal Primer

BISCO’s Z-PRIME Plus is a single-component priming agent used to create adhesion between indirect restorative materials and all resin containing cements.

Z-PRIME Plus - A proprietary Formula of concentrated MDP/Carboxylate monomers has been specifically formulated to address the current weakness in competitor’s primers and create a compelling reason to replacethem immediately!

Z-PRIME™ PlusBisco

Bisco Products v.s. Zirconia/Silane Competitors

Clearfil CeramicKuraray

Monobond PlusIvoclar Vivadent

Product Applications Components

Zirconia, Alumina, Metal

Silica-ceramics

Zirconia, Alumina, Metal, Silica-ceramics

Zirconia, Alumina, Metal, Silica-ceramics

BPDM, Phosphate,Ethanol

Silane

Phosphate, Silane*Ethanol

Phosphate, Silane*Ethanol

*: Silane is not stable in the presence of acidic phosphate monomer.

Porcelain PrimerBisco

Issue of Silane Incorporation into Zirconia Primers

Clearfil CeramicKuraray

Monobond PlusIvoclar Vivadent

Porcelain PrimerBisco

Silane Primer Zirconia/Silane Primer

Contain: Silane Contain: Silane & Acidic Phosphate

Silane Methacrylate De-activation of SilanePre-hydrolyzed Silane

OR

Si

O

OCH3

OCH3

OCH3 AcidO

RSi

O

OH

OH

OH

Dimer, Oligomer, Polymer

pH 5.0 3.1 3.7

To maintain a good shelf-life, pH of one-bottle silane primer systems should be adjusted to 4-5.

Self-Condensation of Hydrolyzed Silane

Z-PRIME PlusIndications For Use

BISCO’s Z-PRIME™ PLUS is intended for use as a surface treatment for the following indirect restoration substrates:

Zirconia (e.g. Lava, Cerec, Implant & others) Alumina (e.g. Procera) Metal/alloy (Titanium, PFM, Non-Precious, High

Noble) Composite (Direct & Indirect) Endodontic Posts (Zirconia, Metal, Fiber) Intra-oral repairs

Using the new primer had a significant effect on increasing the bond strength to zirconia of the tested cements between 86% and 160% increase.

G. MILLAN, M. RAAD, M. ATTAR, and D. NATHANSON, Primer Effect on Bond Strength of Resin Cements to Zirconia, J Dent Res 89(Spec Issue A): Abstr. 1018, 2010

Primer Effect on Bond Strength of Resin Cements to Zirconia

Strong Bond Strengths to Different Substrates

23 MPa

Cement-Self Cured

Zirconia

18 MPaAlumina

3 MPa

With Z-PRIME™ Plus with no primer

4 MPa

22 MPaTitanium

23 MPaNon-precious

24 MPaStainless Steel

20 MPaGold

27 MPaComposite

Unique Benefits

Unparalleled bond strengths to Zirconia, Alumina and Metal Restorations

High S/C & L/C Bonds

SBS of Z-PRIME™ Plus on Different Dental Substrates w/ Duolink™

0 5 10 15 20 25 30 35

Fiber Post

Composite

Gold

Rex III

Option

Stainless Steel

Titanium

Ceramic

Alumina

Zirconia

SBS(MPa)

No PrimerZPRIME+ -S/CZPRIME+ -L/C

Bisco’s new DuoLink™ SE Kit including Z-PRIME Plus and Bis-Silane™ offers a system that provides “Confidence in Indirect Adhesion. The stability of the chemistry is demonstrated by not requiring refrigeration…

New

Z-PRIME™ PlusBisco Released 2009

Clearfil CeramicKuraray

AZ PrimerShofuReleased 2009

Metal/Zr PrimerIvoclar Vivadent

Monobond PlusIvoclar VivadentReleased 2009

Product Applications Components Shelf-life

2y/room temp. 2y/r.t.*(Duolink™)

2y/rom temp.2y/refrig.*(ResiCem)

2y/room temp.2y/refrig.*(Multilink)

2y/room temp.2y/refrig.*(Multilink

2y/refrig2y/refrig.*(Panavia)

Zirconia, Alumina, Metal

Zirconia, Alumina

Zirconia, Alumina, Metal

Zirconia, Alumina, Metal, Silica-ceramics

Zirconia, Alumina, Metal, Silica-ceramics

BPDM, Phosphate,Ethanol

Phosphonate,Acetone

Phosphonate, t-butyl alcohol

Phosphate, Silane**Ethanol

Phosphate, Silane**Ethanol

*: Shelf-life of its corresponding cement. **: Silane is not stable in the present of acidic phosphate monomer.

Competitors

Compatible with light-cured and dual-cured resin luting cements

Unique Benefits

Z-PRIME™ PlusDuolink™Bisco

29 MPa

8 MPaClearfil CeramicPanavia F2.0Kuraray

21 MPaAZ PrimerResiCemShofu

Cement-Light Cured

16 MPaMetal/Zr PrimerMultilink AutomixIvoclar Vivadent

26 MPaMonobond PlusMultilink AutomixIvoclar Vivadent

Stronger Bonding: SBS to Zirconia

Z-PRIME™ PlusDuolink™Bisco

23 MPa

9 MPaClearfil CeramicPanavia F2.0Kuraray

13 MPaAZ PrimerResiCemShofu

Cement-Self Cured

8 MPaMetal/Zr PrimerMultilink AutomixIvoclar Vivadent

11 MPaMonobond PlusMultilink AutomixIvaclar Vivadent

Stronger Bonding: SBS to Zirconia

Z-PRIME™ PlusDuolink™Bisco

Durable Bonding: SBS to Zirconia After Aging

Clearfil CeramicPanavia F2.0Kuraray

AZ PrimerResiCemShofu

Aged 3 days in boiling water, equiv. to 6 years at 37 °C. Cement-Light Cured.

Monobond PlusMultilink AutomixIvoclar Vivadent

29 MPa (Day 1) 28 MPa (6 years)

8 MPa (Day 1) 3 MPa (6 years)

21 MPa (Day 1) 18 MPa (6 years)

26 MPa (Day 1) 16 MPa (6 years)

Z-PRIME™ PlusDuolink™Bisco

Durable Bonding: SBS to Zirconia After Aging

Clearfil CeramicPanavia F2.0Kuraray

AZ PrimerResiCemShofu

Aged 3 days in boiling water, equiv. to 6 years at 37 °C. Cement-Self Cured.

Monobond PlusMultilink AutomixIvoclar Vivadent

23 MPa (Day 1) 16 MPa (6 years)

9 MPa (Day 1) 2 MPa (6 years)

13 MPa (Day 1) 6 MPa (6 years)

11 MPa (Day 1) 7 MPa (6 years)

Comparison of Zirconia Restoration Luting Options: SBS to Zirconia

23 MPa

Cement-Self Cured

Primer w/ Resin Cement

Self-Adhesive Resin Cements

Resin Modified Glass Ionomer Cements

8 MPa

4 MPaRelyX Luting+

(3M ESPE)

FujiCEM (GC)

SmartCem2 (Dentsply)

BisCem (Bisco)

UniCem (3M ESPE)

Z-Prime™ Plus w/ Duolink™ (Bisco)

Duolink (Bisco)

12 MPa

11 MPa

Traditional Resin Cement without Primer (Control)

4 MPa

6 MPa

Average Shear Bond Strength of Zirconia Primers with their Corresponding Self-cure Resin

Cements

Contains:Phosphate Monomer (MDP), BPDM, ethanol

Strong Bond between Resin-cements/composites and:ZirconiaAluminaMetals Titanium, Stainless steel, Rexilium, Option, GoldCompositesInstruction for Use:Apply 1-2 coatsDryProceed with cementation. Zr, Al, or

Metal etcDentin

Z-PRIME PLUS

Duolink

Technique For Placement

Clean the internal surface of the restoration; rinse and air dry.

Apply 1-2 coats of Z-PRIME™ Plus, uniformly wetting the internal surface. Dry with an air syringe for 3-5 seconds.

Proceed with cementation using a luting cement (e.g. DUO-LINK™).

ZrD BisCem

For Full/Retentive Zr Crowns use Biscem® with Z-PRIME™ Plus

Z-P

rime

Cementing Zirconia Crowns

ZrDDuoLink Cement

Short/Tapered, Non-retentive Zr Crown adhesively bond with Resin Cement

Z-P

rime

Ad

hesive

Bonding Zirconia Crowns

“Improved marginal adaptation, prevention of microleakage,increased fracture strength, and increased retention insituations where mechanical retention does not exist constitute the benefits of a stable and durable resin bond tozirconia.”

Magne P, et al. New zirconia primer improves bond strength of resin-based cements. Dent Mater (2009), doi:10.1016/j.dental.2009.12.005

New zirconia primer improves bond strength of resin-based cements.

“The groups where the experimental zirconia primer (ZrP-groups) was used presented the highest mean bond strength values.”

“The groups that did not receive the experimental primer (NP groups)and the group treated with the MDP-containing primer(CCP-group) presented the lowest mean bond strength values”

Magne P, et al. New zirconia primer improves bond strength of resin-based cements. Dent Mater (2009), doi:10.1016/j.dental.2009.12.005

New zirconia primer improves bond strength of resin-based cements.

“ “Confidence in Adhesion”Confidence in Adhesion”

Proprietary MDP and carboxylic acid monomers

Significantly enhances bond strengths of other resin cements*

Compatible with light-cured and dual-cured resin luting cement

Convenient, single bottle delivery offers ease of dispensing

Fast/Predictable Cementation

*Data on file, BISCO, Inc.*Data on file, BISCO, Inc.