table s3. changes in mirna expression in polarized mdms ... · microrna expression in polarized...
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MicroRNA expression in polarized macrophages
Table S3. Changes in miRNA expression in polarized MDMs relative to untreated controls. miRNA identity and assay # No
Treatment M1 M2a M2b M2c Mean Fold Change
D1 D2 D3 D1 D2 D3 D1 D2 D3 D1 D2 D3 D1 D2 D3 M1 M2a M2b M2c
hsa-let-7a*-4395418 1 1 1 0.81 0.791 0.603 0.584 1.155 1.045 0.884 1.117 1.152 1.687 0.825 0.408 0.735 0.928 1.051 0.973
hsa-let-7a-4373169 1 1 1 0.937 1.095 1.139 0.948 1.001 1.18 0.874 0.927 0.974 0.973 0.838 1.289 1.057 1.043 0.925 1.033
hsa-let-7b-4395446 1 1 1 1.656 0.704 0.442 0.729 0.735 0.846 1.219 0.69 0.669 1.299 0.698 0.875 0.934 0.770 0.859 0.957
hsa-let-7c-4373167 1 1 1 0.706 0.932 0.834 0.681 1.169 0.805 0.699 0.821 0.778 0.684 1.007 0.752 0.824 0.885 0.766 0.814
hsa-let-7d-4395394 1 1 1 0.845 0.818 1.167 0.861 0.889 1.079 1.001 0.883 0.878 0.953 0.863 1.538 0.943 0.943 0.921 1.118
hsa-let-7e*-4395518 1 1 1 3.176 0.673 3.042 0.776 0.711 2.621 1.284 0.388 2.84 1.93 0.566 0.719 2.297 1.369 1.504 1.072
hsa-let-7e-4395517 1 1 1 0.928 0.763 1.138 1.04 0.675 0.933 0.861 0.785 0.859 1.035 0.743 1.16 0.943 0.883 0.835 0.979
hsa-let-7f-4373164 1 1 1 0.672 0.625 0.968 0.885 0.625 0.743 0.922 0.651 0.598 0.708 0.605 0.885 0.755 0.751 0.724 0.733
hsa-let-7g*-4395229 1 1 1 0.87 0.715 0.847 0.909 0.6 1.032 0.939 0.567 0.907 0.998 0.286 0.7 0.811 0.847 0.804 0.661
hsa-let-7g-4395393 1 1 1 1.307 1.029 1.228 1.177 1.039 0.843 1.009 1.105 0.906 1.032 0.999 0.982 1.188 1.020 1.007 1.004
hsa-let-7i*-4395283 1 1 1 1.168 1.692 0.817 0.788 1.596 1.03 1.052 1.063 0.512 0.944 0.851 0.695 1.226 1.138 0.876 0.830
hsa-miR-100-4373160 1 1 1 0.565 1.147 1.099 0.449 0.948 6.866 0.571 1.009 1.442 0.453 0.836 1.088 0.937 2.754 1.007 0.792
hsa-miR-101-4395364 1 1 1 1.03 1.157 0.814 1.039 1.104 1.039 1.17 1.095 0.971 0.982 1.078 1.111 1.000 1.061 1.079 1.057
hsa-miR-103-4373158 1 1 1 0.988 0.92 0.947 1.031 0.876 0.93 0.987 0.96 0.852 0.946 0.833 1.013 0.952 0.946 0.933 0.931
hsa-miR-106a-4395280 1 1 1 1.098 1.037 0.732 1.106 1.015 0.812 1.012 0.986 0.811 1.018 0.909 0.865 0.956 0.978 0.936 0.931
hsa-miR-106b*-4395491 1 1 1 0.928 0.999 1.107 1.094 0.734 0.934 0.879 1.03 0.971 0.741 0.928 1.04 1.011 0.921 0.960 0.903
hsa-miR-106b-4373155 1 1 1 1.335 1.215 0.965 1.262 1.048 0.897 1.15 0.999 0.881 1.083 0.912 0.996 1.172 1.069 1.010 0.997
hsa-miR-10a-4373153 1 1 1 0.936 0.874 1.141 0.9 0.865 0.969 0.87 0.843 1.003 0.9 0.825 1.039 0.984 0.911 0.905 0.921
hsa-miR-122-4395356 1 1 1 0.642 0.99 1.278 0.717 0.693 1.044 0.819 1.088 1.273 0.64 1.14 1.44 0.970 0.818 1.060 1.073
hsa-miR-125a-3p-4395310 1 1 1 2.254 3.529 2.002 0.601 1.104 1.013 1.086 2.223 0.926 1.044 0.955 1.25 2.595 0.906 1.412 1.083
hsa-miR-125a-5p-4395309 1 1 1 1.053 1.297 0.789 0.717 0.996 0.954 0.883 1.11 0.727 0.718 0.913 0.81 1.046 0.889 0.907 0.814
hsa-miR-125b-4373148 1 1 1 1.126 1.485 1.016 1.268 0.908 1.136 1.153 1.102 1.092 0.792 0.891 1.046 1.209 1.104 1.116 0.910
hsa-miR-126*-4373269 1 1 1 1.206 1.254 0.707 0.912 1.065 0.895 1.038 1.258 0.933 0.91 0.928 0.881 1.056 0.957 1.076 0.906
hsa-miR-126-4395339 1 1 1 1.064 1.09 0.817 0.981 1.026 0.895 1.188 1.129 0.944 1.172 0.988 0.904 0.990 0.967 1.087 1.021
hsa-miR-127-3p-4373147 1 1 1 0.558 0.712 0.904 0.498 0.886 0.998 0.794 1.106 0.694 0.536 0.962 0.874 0.725 0.794 0.865 0.791
hsa-miR-128-4395327 1 1 1 0.825 1.073 0.835 0.961 1.041 0.763 0.854 1.025 0.731 0.832 1.006 0.819 0.911 0.922 0.870 0.886
hsa-miR-130a-4373145 1 1 1 0.921 1.174 1.124 0.993 0.891 1.087 0.774 0.828 0.847 0.755 0.74 1.23 1.073 0.990 0.816 0.908
hsa-miR-130b*-4395225 1 1 1 1.017 1.203 0.48 0.857 1.296 0.764 0.869 1.456 0.619 0.844 0.885 0.658 0.900 0.972 0.981 0.796
hsa-miR-130b-4373144 1 1 1 0.696 1 0.909 0.778 1.066 1.181 0.95 1.173 0.961 0.738 0.972 1.184 0.868 1.008 1.028 0.965
MicroRNA expression in polarized macrophages
hsa-miR-132*-4395243 1 1 1 1.87 1.913 1.225 0.726 1.009 0.522 3.911 4.698 1.261 0.877 1.229 0.958 1.669 0.752 3.290 1.021
hsa-miR-132-4373143 1 1 1 1.301 1.798 0.852 0.939 0.986 0.738 1.902 1.889 0.921 0.838 0.834 0.844 1.317 0.888 1.571 0.839
hsa-miR-133a-4395357 1 1 1 0.818 1.049 0.59 0.818 0.964 0.68 0.895 0.89 0.706 0.81 0.755 9.268 0.819 0.821 0.830 3.611
hsa-miR-135a*-4395343 1 1 1 1.173 1.124 0.753 0.937 1.15 0.892 0.971 1.196 0.759 0.981 0.996 0.779 1.017 0.993 0.975 0.919
hsa-miR-135a-4373140 1 1 1 0.463 1.085 0.564 0.653 0.555 1.341 0.787 0.57 0.667 0.531 0.711 1.049 0.704 0.850 0.675 0.764
hsa-miR-135b-4395372 1 1 1 1.019 0.927 0.981 1.031 1.026 0.797 0.952 0.909 0.729 1.254 0.867 0.81 0.976 0.951 0.863 0.977
hsa-miR-136*-4395211 1 1 1 1.198 1.025 0.639 2.639 0.49 1.421 0.826 0.828 1.028 0.566 1.025 1.363 0.954 1.517 0.894 0.985
hsa-miR-137-4373301 1 1 1 1.872 0.865 1.051 2.238 0.461 1.729 2.002 0.652 1.26 1.585 0.922 1.794 1.263 1.476 1.305 1.434
hsa-miR-138-1*-4395273 1 1 1 0.856 1.202 1.616 1.054 1.164 1.29 0.803 1.124 1.636 1.005 1.656 1.644 1.225 1.169 1.188 1.435
hsa-miR-138-4395395 1 1 1 0.986 1.633 0.827 1.358 1.145 0.761 0.96 1.206 0.88 1.004 1.217 0.811 1.149 1.088 1.015 1.011
hsa-miR-139-5p-4395400 1 1 1 0.893 0.808 0.542 0.719 0.744 0.678 1.191 1.17 0.801 0.751 0.874 1.153 0.748 0.714 1.054 0.926
hsa-miR-140-3p-4395345 1 1 1 1.009 0.968 0.713 0.98 1.012 0.756 1.073 1.045 0.926 1.062 0.963 0.919 0.897 0.916 1.015 0.981
hsa-miR-140-5p-4373374 1 1 1 0.836 1.019 0.773 0.826 1.003 0.804 0.852 1.057 0.762 0.885 1.006 0.928 0.876 0.878 0.890 0.940
hsa-miR-141-4373137 1 1 1 1.385 1.165 1.053 1.181 0.884 1.189 1.547 0.954 1.045 1.424 0.902 1.665 1.201 1.085 1.182 1.330
hsa-miR-142-3p-4373136 1 1 1 1.214 1.256 0.933 1 1.055 1.216 1.181 1.045 0.981 0.949 0.971 1.402 1.134 1.090 1.069 1.107
hsa-miR-142-5p-4395359 1 1 1 1.197 1.391 1.121 1.271 1.274 1.34 1.308 1.151 1.083 1.098 1.206 1.563 1.236 1.295 1.181 1.289
hsa-miR-1-4395333 1 1 1 1.293 1.304 0.786 1.426 1.019 0.579 0.937 3.645 0.41 0.997 1.777 0.751 1.128 1.008 1.664 1.175
hsa-miR-144*-4395259 1 1 1 0.889 1.095 2.811 0.834 0.585 2.645 0.357 0.767 2.025 0.877 0.472 2.617 1.598 1.355 1.050 1.322
hsa-miR-145-4395389 1 1 1 0.796 0.893 0.639 0.953 0.916 0.715 0.982 0.917 0.864 0.873 0.775 0.776 0.776 0.861 0.921 0.808
hsa-miR-146a-4373132 1 1 1 1.152 1.223 1.222 1.077 0.99 0.827 1.254 1.06 0.946 0.974 0.839 0.917 1.199 0.965 1.087 0.910
hsa-miR-146b-3p-4395472 1 1 1 1.559 1.424 1.196 1.065 1.188 0.778 1.427 1.486 0.786 0.996 1.165 0.873 1.393 1.010 1.233 1.011
hsa-miR-146b-5p-4373178 1 1 1 0.894 1.258 0.954 0.871 1.079 0.89 0.967 1.157 0.843 0.833 0.991 0.914 1.035 0.947 0.989 0.913
hsa-miR-147b-4395373 1 1 1 1.507 1.478 1.601 0.908 0.692 0.865 1.618 1.409 1.327 1.111 1.02 1.042 1.529 0.822 1.451 1.058
hsa-miR-148a-4373130 1 1 1 0.671 1.307 1.24 0.921 1.143 1.026 0.872 1.404 1.013 0.82 1.044 1.021 1.073 1.030 1.096 0.962
hsa-miR-148b*-4395271 1 1 1 1.047 0.872 0.902 0.849 1.097 0.85 0.884 0.943 0.917 0.942 0.905 1.012 0.940 0.932 0.915 0.953
hsa-miR-148b-4373129 1 1 1 1.059 1.098 1.255 1.019 1.215 1.03 1.134 1.376 1.042 0.993 1.024 0.941 1.137 1.088 1.184 0.986
hsa-miR-150-4373127 1 1 1 0.958 1.24 0.88 0.966 1.153 0.955 0.929 1.108 0.904 0.93 1.006 0.965 1.026 1.025 0.980 0.967
hsa-miR-151-3p-4395365 1 1 1 1.229 0.899 0.723 1.015 1.21 0.946 1.168 0.969 0.693 1.021 0.831 0.84 0.950 1.057 0.943 0.897
hsa-miR-152-4395170 1 1 1 0.843 0.957 1.018 0.905 1.011 1.006 0.931 1.028 0.945 0.859 0.85 1.047 0.939 0.974 0.968 0.919
hsa-miR-155*-4395398 1 1 1 4.817 4.126 8.945 1.098 2.162 0.95 5.804 6.338 4.174 0.519 0.712 0.837 5.963 1.403 5.439 0.689
hsa-miR-155-4395459 1 1 1 1.15 1.254 1.29 0.633 0.953 0.717 0.819 1.476 1.24 0.484 0.95 0.978 1.231 0.768 1.178 0.804
hsa-miR-15a*-4395530 1 1 1 1.087 1.388 0.696 1.306 1.763 1.066 0.948 1.369 0.755 1.045 1.596 0.974 1.057 1.378 1.024 1.205
hsa-miR-15b-4373122 1 1 1 0.96 1.217 1.094 0.995 0.981 1.063 0.998 1.048 0.917 0.941 0.916 1.085 1.090 1.013 0.988 0.981
hsa-miR-16-1*-4395531 1 1 1 1.426 0.823 0.825 1.478 1.253 1.246 0.896 0.833 0.68 1.431 1.283 1.352 1.025 1.326 0.803 1.355
MicroRNA expression in polarized macrophages
hsa-miR-16-4373121 1 1 1 0.577 0.979 0.966 0.751 0.874 0.786 0.661 0.991 0.775 0.638 0.991 0.764 0.841 0.804 0.809 0.798
hsa-miR-17-4395419 1 1 1 0.899 1.203 0.91 0.787 1.128 0.848 0.738 1.158 0.869 0.762 0.992 0.971 1.004 0.921 0.922 0.908
hsa-miR-181a*-4373086 1 1 1 0.524 0.399 0.597 0.577 0.594 0.962 0.485 0.379 0.84 0.803 0.6 1.109 0.507 0.711 0.568 0.837
hsa-miR-181a-2*-4395428 1 1 1 0.832 0.887 1.276 1.031 1.334 1.22 0.726 0.929 1.076 1.259 1.209 1.022 0.998 1.195 0.910 1.163
hsa-miR-184-4373113 1 1 1 0.847 0.797 1.519 0.987 0.553 0.604 1.011 0.872 1.29 0.776 0.403 1.211 1.054 0.715 1.058 0.797
hsa-miR-185-4395382 1 1 1 0.997 0.947 0.973 1.264 1.027 1.117 1.131 0.899 1.074 1.166 0.944 1.266 0.972 1.136 1.035 1.125
hsa-miR-186-4395396 1 1 1 0.847 1.133 0.792 1.062 1.01 0.92 0.854 1.168 0.782 1.133 1.044 0.889 0.924 0.997 0.935 1.022
hsa-miR-188-5p-4395431 1 1 1 1.118 1.299 0.748 1.172 1.314 1.134 1.154 1.252 0.73 1.182 1.293 0.876 1.055 1.207 1.045 1.117
hsa-miR-18a*-4395534 1 1 1 1.07 1.071 0.961 1.201 1.362 1.202 0.774 0.883 0.649 1.224 0.973 0.892 1.034 1.255 0.769 1.030
hsa-miR-18a-4395533 1 1 1 0.968 1.096 1.012 1.015 1.068 0.789 0.921 1.131 0.803 0.84 0.911 0.924 1.025 0.957 0.952 0.892
hsa-miR-190-4373110 1 1 1 0.747 1.055 0.91 0.821 0.98 1.115 1.297 0.845 0.758 0.803 0.985 1.232 0.904 0.972 0.967 1.007
hsa-miR-190b-4395374 1 1 1 1.31 1.038 0.661 1.089 1.1 0.816 1.194 1.048 0.95 1.084 1.068 0.799 1.003 1.002 1.064 0.984
hsa-miR-191-4395410 1 1 1 0.971 1.054 0.845 1.104 1.112 0.889 1.035 1.073 0.786 1.11 1.039 1.067 0.957 1.035 0.965 1.072
hsa-miR-192*-4395383 1 1 1 1.55 0.654 1.415 0.929 0.958 0.97 1.743 1.342 1.995 1.899 0.569 0.947 1.206 0.952 1.693 1.138
hsa-miR-192-4373108 1 1 1 0.961 1.079 0.999 0.998 0.981 0.926 1.209 1.288 1.232 0.95 0.889 0.94 1.013 0.968 1.243 0.926
hsa-miR-193a-3p-4395361 1 1 1 1.571 1.457 1.178 1.342 1.281 1.261 1.767 1.491 1.225 1.02 1.398 1.428 1.402 1.295 1.494 1.282
hsa-miR-193a-5p-4395392 1 1 1 0.909 1.055 0.988 0.883 0.988 0.868 1.072 1.167 0.855 1.012 1.064 1.079 0.984 0.913 1.031 1.052
hsa-miR-193b-4395478 1 1 1 0.744 0.95 0.897 1.72 3.665 1.558 0.751 0.785 0.799 0.768 0.867 0.782 0.864 2.314 0.778 0.806
hsa-miR-194-4373106 1 1 1 1.107 1.219 1.098 1.122 0.855 0.839 1.339 1.237 0.942 1.115 0.827 0.892 1.141 0.939 1.173 0.945
hsa-miR-195-4373105 1 1 1 1.264 1.006 0.939 1.184 1.152 1.037 1.15 1.044 0.989 1.332 0.923 1.032 1.070 1.124 1.061 1.096
hsa-miR-196b-4395326 1 1 1 0.734 0.671 1.011 0.835 0.764 0.868 1.153 0.886 1.194 0.891 0.612 0.929 0.805 0.822 1.078 0.811
hsa-miR-199a-3p-4395415 1 1 1 0.962 0.957 0.861 1.086 0.879 0.778 1.034 1.003 0.933 0.906 0.864 0.896 0.927 0.914 0.990 0.889
hsa-miR-19a-4373099 1 1 1 0.892 0.931 0.912 0.787 0.982 0.896 0.787 0.8 0.831 0.777 0.914 0.975 0.912 0.888 0.806 0.889
hsa-miR-19b-1*-4395536 1 1 1 1.262 0.977 0.843 1.264 1.385 1.064 1.037 0.922 0.843 1.085 1.021 1.194 1.027 1.238 0.934 1.100
hsa-miR-19b-4373098 1 1 1 1.014 1.069 0.937 1.022 0.96 0.856 1.037 0.953 0.844 0.963 0.889 0.958 1.007 0.946 0.945 0.937
hsa-miR-200b-4395362 1 1 1 0.647 1.054 0.815 0.667 0.85 0.732 0.637 1.073 0.872 0.64 0.83 1.077 0.839 0.750 0.861 0.849
hsa-miR-200c-4395411 1 1 1 1.021 1.103 1.031 0.952 0.876 0.784 0.906 1.002 0.751 0.958 0.851 1.17 1.052 0.871 0.886 0.993
hsa-miR-203-4373095 1 1 1 1.399 1.499 0.731 1.526 1.481 0.982 1.412 1.448 0.764 1.49 0.859 0.901 1.210 1.330 1.208 1.083
hsa-miR-206-4373092 1 1 1 1.146 0.466 1.132 0.969 0.739 0.484 0.771 0.644 0.557 1.476 0.373 0.841 0.915 0.731 0.657 0.897
hsa-miR-20a*-4395548 1 1 1 1.426 1.215 0.918 1.178 1.353 1.055 1.193 0.983 0.985 1.048 0.933 0.931 1.186 1.195 1.054 0.971
hsa-miR-20a-4373286 1 1 1 1.042 0.913 0.901 0.834 0.867 0.958 1.093 0.885 0.922 0.833 0.819 1.015 0.952 0.886 0.967 0.889
hsa-miR-20b-4373263 1 1 1 0.86 0.98 1.01 0.902 0.881 0.938 0.873 0.918 0.972 0.922 0.887 1.044 0.950 0.907 0.921 0.951
hsa-miR-21*-4395549 1 1 1 1.762 1.508 0.918 1.749 2.191 1.616 1.549 1.333 0.866 1.108 1.024 0.94 1.396 1.852 1.249 1.024
hsa-miR-210-4373089 1 1 1 0.864 1.351 1.102 0.897 0.99 0.886 0.843 1.711 1.039 0.674 0.982 0.984 1.106 0.924 1.198 0.880
MicroRNA expression in polarized macrophages
hsa-miR-212-4373087 1 1 1 1.743 2.09 0.793 1.105 1.082 0.841 2.665 2.428 0.987 1.222 0.885 1.006 1.542 1.009 2.027 1.038
hsa-miR-21-4373090 1 1 1 0.756 1.108 1.183 0.774 0.962 0.885 0.748 0.997 0.831 0.614 0.862 0.959 1.016 0.874 0.859 0.812
hsa-miR-218-4373081 1 1 1 0.939 1.318 0.92 0.908 1.106 0.996 1.032 1.079 0.966 0.821 0.933 1.045 1.059 1.003 1.026 0.933
hsa-miR-22*-4395412 1 1 1 1.25 1.041 0.95 0.95 0.948 1.118 1.191 1.022 0.967 0.964 0.864 0.92 1.080 1.005 1.060 0.916
hsa-miR-221*-4395207 1 1 1 2.033 0.986 1.327 1.17 1.105 1.35 1.485 0.791 1.085 0.998 0.646 1.145 1.449 1.208 1.120 0.930
hsa-miR-221-4373077 1 1 1 0.564 0.778 0.58 0.922 1.107 0.977 0.963 1.369 0.76 0.838 1.104 0.999 0.641 1.002 1.031 0.980
hsa-miR-222*-4395208 1 1 1 0.696 0.812 0.338 1.649 1.428 1.356 3.7 3.197 0.644 1.211 0.985 0.984 0.615 1.478 2.514 1.060
hsa-miR-222-4395387 1 1 1 0.853 1.369 0.892 1.07 1.195 1.045 1.269 1.237 0.858 0.924 1.056 0.911 1.038 1.103 1.121 0.964
hsa-miR-223*-4395209 1 1 1 1.127 0.925 0.904 1.014 0.934 1.011 1.124 0.942 0.894 0.991 0.843 1.061 0.985 0.986 0.987 0.965
hsa-miR-223-4395406 1 1 1 0.919 1.091 0.866 0.883 1.228 0.936 1.288 1.319 0.919 0.989 1.206 1.093 0.959 1.016 1.175 1.096
hsa-miR-24-4373072 1 1 1 0.811 0.881 0.821 0.703 0.811 0.823 0.916 0.867 0.779 0.841 0.773 0.885 0.838 0.779 0.854 0.833
hsa-miR-25-4373071 1 1 1 0.943 1.036 0.702 0.875 0.954 0.808 0.97 1.01 0.794 0.822 0.868 0.874 0.894 0.879 0.925 0.855
hsa-miR-26a-2*-4395226 1 1 1 0.296 0.001 0.376 1.034 1.034 1.276 0.497 0.38 0.988 0.876 0.806 1.281 0.224 1.115 0.622 0.988
hsa-miR-26a-4395166 1 1 1 0.792 1.132 0.983 0.909 1.075 0.907 0.916 1.165 0.871 0.872 0.998 1.07 0.969 0.964 0.984 0.980
hsa-miR-26b*-4395555 1 1 1 1.052 0.797 0.515 1.045 1.301 0.806 1.148 1.045 0.645 1.032 0.963 0.796 0.788 1.051 0.946 0.930
hsa-miR-26b-4395167 1 1 1 0.997 1.065 0.817 0.969 0.962 0.938 1.1 1.024 0.834 0.993 1.007 1.132 0.960 0.956 0.986 1.044
hsa-miR-27a*-4395556 1 1 1 1.321 1.234 0.866 0.909 0.979 0.788 2.764 2.515 1.084 1.013 1.211 1.109 1.140 0.892 2.121 1.111
hsa-miR-27a-4373287 1 1 1 0.919 1.018 0.686 1.083 1.123 0.857 1.35 1.383 0.923 1.132 1.114 1.099 0.874 1.021 1.219 1.115
hsa-miR-28-3p-4395557 1 1 1 0.972 1.005 0.847 0.949 0.978 0.863 0.917 0.962 0.822 0.945 0.887 0.952 0.941 0.930 0.900 0.928
hsa-miR-28-5p-4373067 1 1 1 0.814 1.054 1.106 0.868 0.943 0.955 0.811 1.002 0.879 0.776 0.868 1.051 0.991 0.922 0.897 0.898
hsa-miR-29a*-4395558 1 1 1 1.537 1.268 1.239 0.947 1.206 1.209 1.881 1.446 1.15 0.97 0.869 1.001 1.348 1.121 1.492 0.947
hsa-miR-29a-4395223 1 1 1 1.07 1.021 1.144 1.025 0.879 0.809 1.19 1.098 0.886 0.871 0.86 0.844 1.078 0.904 1.058 0.858
hsa-miR-29b-1*-4395276 1 1 1 1.998 1.111 3.112 0.896 0.465 0.768 4.911 2.446 2.274 0.601 0.887 0.733 2.074 0.710 3.210 0.740
hsa-miR-29b-2*-4395277 1 1 1 0.965 0.959 1.243 0.692 0.829 1.031 0.818 0.684 0.758 0.873 0.599 0.798 1.056 0.851 0.753 0.757
hsa-miR-29b-4373288 1 1 1 1.571 1.573 0.957 0.962 1.116 0.996 1.446 1.265 0.974 0.868 1.269 1.213 1.367 1.025 1.228 1.117
hsa-miR-29c*-4381131 1 1 1 1.043 1.107 0.75 0.994 1.312 1.003 0.866 1.066 0.765 0.855 1.01 0.9 0.967 1.103 0.899 0.922
hsa-miR-29c-4395171 1 1 1 1.212 1.082 0.964 1.011 0.879 1.118 1.342 0.927 1.081 0.94 0.904 1.147 1.086 1.003 1.117 0.997
hsa-miR-301a-4373064 1 1 1 1.241 1.134 0.599 1.146 1.173 0.849 1.413 1.289 0.847 1.194 1.085 0.959 0.991 1.056 1.183 1.079
hsa-miR-301b-4395503 1 1 1 0.766 1.061 0.779 0.899 1.153 0.986 0.902 1.398 0.872 0.852 0.996 0.959 0.869 1.013 1.057 0.936
hsa-miR-30a*-4373062 1 1 1 0.969 0.646 0.908 0.72 0.99 1.154 0.899 0.916 1.35 0.733 0.933 1.048 0.841 0.955 1.055 0.905
hsa-miR-30a-4373061 1 1 1 1.191 1.01 0.79 0.967 1.046 0.952 1.201 1.025 0.886 0.986 0.83 0.919 0.997 0.988 1.037 0.912
hsa-miR-30b-4373290 1 1 1 0.938 0.963 0.939 0.874 0.88 0.881 0.922 0.902 0.871 0.872 0.825 1.042 0.947 0.878 0.898 0.913
hsa-miR-30c-4373060 1 1 1 0.922 0.946 0.979 0.955 0.744 0.822 0.813 0.808 0.738 0.857 0.73 0.969 0.949 0.840 0.786 0.852
hsa-miR-30d*-4395416 1 1 1 0.67 0.631 0.615 0.845 1.238 0.922 0.807 0.869 0.827 0.892 0.962 0.973 0.639 1.002 0.834 0.942
MicroRNA expression in polarized macrophages
hsa-miR-30d-4373059 1 1 1 1.072 0.977 0.813 0.812 0.944 0.924 1.102 0.904 0.726 0.859 0.704 0.769 0.954 0.893 0.911 0.777
hsa-miR-30e*-4373057 1 1 1 1.009 0.975 0.699 0.963 1.178 0.88 1.123 1.015 0.725 0.944 0.969 0.858 0.894 1.007 0.954 0.924
hsa-miR-30e-4395334 1 1 1 1.299 1.2 0.808 1.08 1.293 0.983 1.331 1.104 0.862 1.046 1.079 0.951 1.102 1.119 1.099 1.025
hsa-miR-31-4395390 1 1 1 0.968 0.924 1.069 1.074 0.938 1.004 0.939 0.866 1.013 0.931 0.76 0.978 0.987 1.005 0.939 0.890
hsa-miR-320-4395388 1 1 1 0.944 1.073 0.873 0.995 0.987 0.925 1.067 1.061 0.859 1.096 1.011 1.126 0.963 0.969 0.996 1.078
hsa-miR-32-4395220 1 1 1 1.607 0.878 1.07 1.295 0.946 1.203 1.958 0.777 0.857 1.249 0.802 1.518 1.185 1.148 1.197 1.190
hsa-miR-324-3p-4395272 1 1 1 0.915 0.807 0.741 0.987 0.982 0.684 0.977 0.848 0.729 1.007 0.817 0.879 0.821 0.884 0.851 0.901
hsa-miR-324-5p-4373052 1 1 1 0.802 1.261 1.017 1.032 1.181 1.122 0.967 1.115 0.86 0.746 1.203 1.049 1.027 1.112 0.981 0.999
hsa-miR-328-4373049 1 1 1 0.791 1.049 0.78 0.948 1.092 0.89 0.881 0.966 0.75 0.906 0.964 0.923 0.873 0.977 0.866 0.931
hsa-miR-331-3p-4373046 1 1 1 1.063 0.994 0.794 1.144 1.029 0.717 1.025 0.994 0.68 1.057 0.821 0.795 0.950 0.963 0.900 0.891
hsa-miR-335-4373045 1 1 1 0.686 0.803 1.238 0.792 0.692 1.328 0.509 0.694 2.196 0.489 0.597 1.393 0.909 0.937 1.133 0.826
hsa-miR-338-3p-4395363 1 1 1 0.922 1.558 0.869 1.274 1.132 1.027 1.01 1.11 1.075 0.998 1.019 0.972 1.116 1.144 1.065 0.996
hsa-miR-339-3p-4395295 1 1 1 0.744 0.818 0.604 0.913 0.881 0.835 0.702 0.718 0.699 0.963 0.972 0.871 0.722 0.876 0.706 0.935
hsa-miR-33a*-4395247 1 1 1 1.022 1.209 0.827 0.762 1.026 0.934 0.934 0.946 0.798 0.726 1.075 0.727 1.019 0.907 0.893 0.843
hsa-miR-340*-4395370 1 1 1 1.052 0.988 0.712 0.975 1.088 0.948 0.991 0.945 0.76 0.94 0.888 1.015 0.917 1.004 0.899 0.948
hsa-miR-340-4395369 1 1 1 0.947 0.791 0.807 0.976 0.795 1.055 1.08 0.827 0.911 1.002 0.788 1.295 0.848 0.942 0.939 1.028
hsa-miR-342-3p-4395371 1 1 1 1.03 1.056 0.68 1.017 0.916 0.846 1.046 0.888 0.764 1.051 0.886 1.012 0.922 0.926 0.899 0.983
hsa-miR-345-4395297 1 1 1 0.653 0.961 0.655 0.869 1.041 0.793 0.739 1.033 0.704 0.809 1.071 0.885 0.756 0.901 0.825 0.922
hsa-miR-34a*-4395427 1 1 1 1 1.015 0.818 0.829 1.123 0.984 0.97 0.883 0.851 1.018 1.016 1.062 0.944 0.979 0.901 1.032
hsa-miR-34a-4395168 1 1 1 0.958 1.184 0.888 0.98 1.087 0.849 1.078 1.071 0.843 0.881 0.975 0.914 1.010 0.972 0.997 0.923
hsa-miR-362-3p-4395228 1 1 1 1.012 1.16 0.908 0.906 1.103 1.042 1.307 0.952 0.996 0.864 0.965 1.236 1.027 1.017 1.085 1.022
hsa-miR-362-5p-4378092 1 1 1 0.781 0.922 0.778 0.806 0.843 0.89 0.715 0.891 0.808 0.803 0.893 1.046 0.827 0.846 0.805 0.914
hsa-miR-363-4378090 1 1 1 1.121 1.18 0.968 1.086 1.049 1.33 0.998 0.95 1.028 0.953 0.78 1.224 1.090 1.155 0.992 0.986
hsa-miR-365-4373194 1 1 1 0.865 0.912 0.674 0.841 0.915 0.819 1.103 0.91 0.745 0.866 0.771 0.943 0.817 0.858 0.919 0.860
hsa-miR-374a*-4395236 1 1 1 1.572 1.229 0.683 1.041 1.034 0.919 1.201 0.614 0.719 1.287 0.903 1.14 1.161 0.998 0.845 1.110
hsa-miR-374a-4373028 1 1 1 0.822 0.974 0.853 0.847 0.909 1.028 0.833 0.928 0.927 0.915 0.879 1.161 0.883 0.928 0.896 0.985
hsa-miR-374b*-4395502 1 1 1 0.678 0.516 2.32 1.442 1.682 4.971 0.613 0.453 4.45 0.413 1.172 4.644 1.171 2.698 1.839 2.076
hsa-miR-374b-4381045 1 1 1 0.752 1.166 0.768 0.876 1.117 0.907 0.821 1.093 0.846 0.978 1.127 1.135 0.895 0.967 0.920 1.080
hsa-miR-376a-4373026 1 1 1 0.795 0.759 0.919 1.056 0.935 0.994 0.915 0.542 0.964 0.779 0.725 1.035 0.824 0.995 0.807 0.846
hsa-miR-376c-4395233 1 1 1 0.847 1.037 0.743 0.68 0.895 1.055 1.016 0.908 0.946 1.067 0.815 0.954 0.876 0.877 0.957 0.945
hsa-miR-378*-4373024 1 1 1 1.048 0.867 0.888 0.886 1.384 1.153 1.092 1.023 1.032 0.891 0.954 1.125 0.934 1.141 1.049 0.990
hsa-miR-378-4395354 1 1 1 1.176 0.965 0.836 1.041 1.291 0.996 1.158 1.041 0.768 1.001 0.93 0.868 0.992 1.109 0.989 0.933
hsa-miR-409-3p-4395443 1 1 1 0.837 0.957 1.115 0.754 0.611 1.092 1.37 1.05 1.734 1.059 0.629 0.959 0.970 0.819 1.385 0.882
hsa-miR-411-4381013 1 1 1 3.127 0.742 0.775 1.014 0.832 0.805 0.867 0.92 1.099 1.874 0.845 0.62 1.548 0.884 0.962 1.113
MicroRNA expression in polarized macrophages
hsa-miR-422a-4395408 1 1 1 0.554 0.675 0.667 0.851 0.954 0.635 0.718 0.899 0.548 0.73 0.954 0.844 0.632 0.813 0.722 0.843
hsa-miR-424*-4395420 1 1 1 0.989 0.741 1.383 1.337 0.767 0.526 1.162 1.115 1.651 1.083 0.92 1.473 1.038 0.877 1.309 1.159
hsa-miR-424-4373201 1 1 1 1.184 1.18 1.107 1.291 1.073 1.046 1.214 1.157 0.891 0.88 0.909 0.855 1.157 1.137 1.087 0.881
hsa-miR-425*-4395413 1 1 1 0.794 1.068 0.629 0.781 1.406 1.02 0.829 1.243 0.701 0.848 1.066 0.85 0.830 1.069 0.924 0.921
hsa-miR-429-4373203 1 1 1 0.794 0.644 0.812 0.928 1.108 0.983 0.875 0.937 0.849 0.78 0.581 1.021 0.750 1.006 0.887 0.794
hsa-miR-449a-4373207 1 1 1 1.005 1.332 1.169 0.95 1.734 0.927 1.047 1.542 0.968 0.707 1.374 0.665 1.169 1.204 1.186 0.915
hsa-miR-449b-4381011 1 1 1 1.32 1.715 1.149 0.957 0.808 0.742 1.524 1.35 0.963 1.068 0.779 0.94 1.395 0.836 1.279 0.929
hsa-miR-450a-4395414 1 1 1 0.786 1.244 0.84 0.795 0.963 0.729 0.7 1.292 0.793 0.843 1.161 0.89 0.957 0.829 0.928 0.965
hsa-miR-451-4373360 1 1 1 0.97 1.114 1.102 1.003 1.481 1.207 0.678 1.424 1.252 0.86 1.282 0.828 1.062 1.230 1.118 0.990
hsa-miR-454*-4395185 1 1 1 1.351 0.703 0.753 1.043 0.895 0.993 1.312 0.831 0.705 1.088 0.791 0.901 0.936 0.977 0.949 0.927
hsa-miR-454-4395434 1 1 1 0.843 1.057 0.756 0.936 0.897 0.793 0.958 0.964 0.787 1.014 0.966 0.958 0.885 0.875 0.903 0.979
hsa-miR-483-5p-4395449 1 1 1 0.484 0.898 0.527 0.66 1.22 0.884 1.039 1.711 1.297 0.853 1.26 0.958 0.636 0.921 1.349 1.024
hsa-miR-484-4381032 1 1 1 0.838 0.879 0.723 0.934 0.845 0.715 0.994 0.825 0.712 0.891 0.866 0.777 0.813 0.831 0.844 0.845
hsa-miR-487b-4378102 1 1 1 0.85 1.336 0.932 0.765 2.231 0.584 0.457 2.281 1.601 0.959 1 1.385 1.039 1.193 1.446 1.115
hsa-miR-491-5p-4381053 1 1 1 0.87 0.986 0.962 0.899 0.873 0.973 0.892 0.976 0.893 0.887 0.925 1.06 0.939 0.915 0.920 0.957
hsa-miR-494-4395476 1 1 1 0.92 1.249 1.165 0.825 0.984 0.96 0.899 2.023 0.973 0.597 2.814 0.993 1.111 0.923 1.298 1.468
hsa-miR-495-4381078 1 1 1 0.83 2.398 2.471 0.618 3.683 1.728 0.684 1.958 2.486 0.871 1.869 2.435 1.900 2.010 1.709 1.725
hsa-miR-500*-4373225 1 1 1 0.938 0.875 0.894 1.022 0.888 1.584 0.641 0.678 0.56 0.927 1.05 1.124 0.902 1.165 0.626 1.034
hsa-miR-500-4395539 1 1 1 0.989 1.299 0.706 1.118 1.177 0.767 1.094 1.289 0.87 1.027 1.057 0.882 0.998 1.021 1.084 0.989
hsa-miR-502-3p-4395194 1 1 1 0.98 1.16 1.049 1.088 1.013 1.011 0.969 1.109 0.939 0.813 0.952 1.168 1.063 1.037 1.006 0.978
hsa-miR-502-5p-4373227 1 1 1 0.986 1.339 0.831 0.912 1.078 1.118 1.111 1.126 0.839 0.971 0.947 1.403 1.052 1.036 1.025 1.107
hsa-miR-503-4373228 1 1 1 0.96 1.285 1.649 0.929 1.957 1.287 0.875 1.589 1.32 0.872 1.706 1.404 1.298 1.391 1.261 1.327
hsa-miR-505*-4395198 1 1 1 1.028 1.136 0.773 0.808 1.051 0.959 0.822 0.96 0.823 0.886 0.84 0.91 0.979 0.939 0.868 0.879
hsa-miR-505-4395200 1 1 1 1.186 0.927 0.599 1.08 0.856 0.736 1.443 1.136 0.713 1.152 0.797 0.893 0.904 0.891 1.097 0.947
hsa-miR-509-3p-4395347 1 1 1 0.965 1.987 1.381 1.272 1.961 0.597 0.951 1.343 1.473 0.983 2.081 0.848 1.444 1.277 1.256 1.304
hsa-miR-511-4373236 1 1 1 1.024 1.049 0.694 1.176 1.125 0.79 1.065 1.056 0.728 1.062 0.967 0.774 0.922 1.030 0.950 0.934
hsa-miR-516a-3p-4373183 1 1 1 0.557 2.163 1.237 1.23 1.946 1.435 1.169 0.8 1.111 1.341 3.01 1.313 1.319 1.537 1.027 1.888
hsa-miR-520c-3p-4395511 1 1 1 1.958 1.159 0.993 0.856 1.209 1.359 1.025 0.559 0.588 1.285 0.789 1.226 1.370 1.141 0.724 1.100
hsa-miR-532-3p-4395466 1 1 1 0.834 1.118 0.829 0.901 1.013 0.764 0.809 1.02 0.704 0.781 0.903 0.851 0.927 0.893 0.844 0.845
hsa-miR-532-5p-4380928 1 1 1 0.885 1.09 0.756 0.942 1.083 0.81 0.96 1.141 0.729 1.022 0.991 0.873 0.910 0.945 0.943 0.962
hsa-miR-542-3p-4378101 1 1 1 0.926 1.059 0.635 0.892 1.191 1.898 0.937 1.183 1.387 0.752 0.863 1.492 0.873 1.327 1.169 1.036
hsa-miR-545*-4395377 1 1 1 0.763 0.912 0.567 0.647 0.787 0.965 1.028 0.542 0.755 0.868 0.941 1.087 0.747 0.800 0.775 0.965
hsa-miR-545-4395378 1 1 1 0.833 1.822 1.297 1.144 1.552 1.167 1.228 1.344 1.233 0.874 1.636 1.476 1.317 1.288 1.268 1.329
hsa-miR-548c-5p-4395540 1 1 1 1.387 0.689 1.024 3.308 1.212 1.31 2.713 1.08 1.339 2.859 1.01 1.367 1.033 1.943 1.711 1.745
MicroRNA expression in polarized macrophages
hsa-miR-565-4380942 1 1 1 1.409 1.167 1.638 1.139 0.829 1.57 1.059 0.892 1.309 0.784 0.978 1.624 1.405 1.179 1.087 1.129
hsa-miR-572-4381017 1 1 1 0.61 0.765 2.088 0.799 1.389 2.213 0.518 0.546 2.119 0.602 0.599 1.892 1.154 1.467 1.061 1.031
hsa-miR-574-3p-4395460 1 1 1 0.852 1.054 0.862 0.967 1.065 0.851 0.932 1.189 0.973 0.876 0.955 0.971 0.923 0.961 1.031 0.934
hsa-miR-576-3p-4395462 1 1 1 0.862 0.786 0.93 1.037 0.803 1.451 1.128 0.745 1.073 1.351 0.797 1.474 0.859 1.097 0.982 1.207
hsa-miR-579-4395509 1 1 1 1.049 1.251 0.941 1.002 0.821 0.956 0.968 1.158 0.826 0.891 1.005 0.974 1.080 0.926 0.984 0.957
hsa-miR-589*-4380953 1 1 1 0.966 0.493 0.869 0.838 0.591 0.937 0.9 0.64 1.147 0.904 0.406 1.347 0.776 0.789 0.896 0.886
hsa-miR-589-4395520 1 1 1 0.647 0.467 0.767 1.146 0.705 0.663 2.004 0.612 0.929 1.024 0.599 1.604 0.627 0.838 1.182 1.076
hsa-miR-590-5p-4395176 1 1 1 1.084 1.272 0.8 1.161 1.188 0.92 1.385 1.092 0.905 1.149 1.201 1.28 1.052 1.090 1.127 1.210
hsa-miR-597-4380960 1 1 1 1.151 1.002 1.018 1.434 1.329 0.915 1.135 1.253 0.803 1.058 1.142 1.116 1.057 1.226 1.064 1.105
hsa-miR-598-4395179 1 1 1 0.997 0.918 0.883 0.971 1.042 0.853 1.026 0.919 0.766 1.136 1.027 1.042 0.933 0.955 0.904 1.068
hsa-miR-601-4380965 1 1 1 0.81 0.994 0.946 0.719 1.164 1.359 1.106 1.27 1.374 1.005 1.492 1.166 0.917 1.081 1.250 1.221
hsa-miR-616*-4380992 1 1 1 1.117 0.994 0.713 1.017 1.004 0.753 1.054 1.034 0.641 0.865 0.938 0.913 0.941 0.925 0.910 0.905
hsa-miR-618-4380996 1 1 1 0.758 0.624 0.489 0.913 0.525 0.332 0.684 0.697 0.828 1.007 0.663 0.581 0.624 0.590 0.736 0.750
hsa-miR-624*-4380964 1 1 1 1.842 0.73 1.27 1.096 0.878 1.201 1.501 1.258 0.88 0.64 0.575 0.63 1.281 1.058 1.213 0.615
hsa-miR-625*-4395543 1 1 1 0.957 0.861 1.094 1.071 0.946 0.987 0.933 0.837 1.032 0.941 1.024 1.137 0.971 1.001 0.934 1.034
hsa-miR-625-4395542 1 1 1 0.679 0.928 1.022 0.837 0.942 0.922 0.778 0.889 0.805 0.96 0.984 1.039 0.876 0.900 0.824 0.994
hsa-miR-627-4380967 1 1 1 0.469 1.548 0.797 0.675 1.482 1.34 0.748 1.393 0.733 0.369 1.269 1.518 0.938 1.166 0.958 1.052
hsa-miR-628-3p-4395545 1 1 1 0.883 1.016 0.793 0.888 1.102 0.941 0.766 1.047 0.816 0.991 1.154 0.951 0.897 0.977 0.876 1.032
hsa-miR-628-5p-4395544 1 1 1 0.834 1.073 0.777 0.951 1.065 0.751 0.853 0.895 0.756 1.119 1.142 0.858 0.895 0.922 0.835 1.040
hsa-miR-629*-4380969 1 1 1 0.993 0.792 0.68 0.881 0.862 1.101 0.892 0.876 1.007 0.997 0.727 0.858 0.822 0.948 0.925 0.861
hsa-miR-629-4395547 1 1 1 1.28 1.131 0.728 1.365 0.952 0.82 1.182 1.26 0.793 1.474 1.074 1.077 1.046 1.046 1.078 1.208
hsa-miR-636-4395199 1 1 1 1.279 1.347 0.649 1.266 0.804 0.911 1.254 1.288 0.83 1.098 0.764 1.228 1.092 0.994 1.124 1.030
hsa-miR-642-4380995 1 1 1 0.948 1.194 0.921 0.968 0.992 1.062 1.26 1.037 1.08 0.844 0.925 1.204 1.021 1.007 1.126 0.991
hsa-miR-651-4381007 1 1 1 0.857 1.171 0.829 0.812 0.864 1.093 0.89 1.197 1.376 1.097 1.088 0.952 0.952 0.923 1.154 1.046
hsa-miR-652-4395463 1 1 1 0.947 1.008 0.89 1.074 1.032 0.848 1.092 1.023 0.8 0.938 0.983 0.97 0.948 0.985 0.972 0.964
hsa-miR-660-4380925 1 1 1 0.989 1.252 0.814 1.119 1.093 0.914 0.961 1.217 0.923 0.921 1.127 1.028 1.018 1.042 1.034 1.025
hsa-miR-671-3p-4395433 1 1 1 0.596 0.505 0.599 1.03 0.857 0.833 0.651 0.57 0.602 1.105 0.795 0.994 0.567 0.907 0.608 0.965
hsa-miR-708-4395452 1 1 1 0.997 1.329 0.85 0.979 1.248 0.823 1.119 1.276 1.042 1.109 1.244 0.894 1.059 1.017 1.146 1.082
hsa-miR-7-1*-4381118 1 1 1 0.961 1.053 1.196 0.941 0.914 0.924 1.132 1.108 0.87 0.861 0.943 0.857 1.070 0.926 1.037 0.887
hsa-miR-7-4378130 1 1 1 1.273 1.221 1.088 0.981 1.011 0.992 1.258 0.878 1.132 1.043 0.813 0.867 1.194 0.995 1.089 0.908
hsa-miR-744*-4395436 1 1 1 0.915 0.571 0.726 0.792 1.358 0.73 0.978 0.518 0.767 0.599 0.503 0.675 0.737 0.960 0.754 0.592
hsa-miR-744-4395435 1 1 1 0.853 0.932 0.841 0.913 0.897 0.854 0.943 1.046 0.864 0.886 0.908 0.884 0.875 0.888 0.951 0.893
hsa-miR-766-4395177 1 1 1 0.816 0.993 0.901 0.942 1.071 1.029 0.917 1.18 0.855 1.07 1.224 0.954 0.903 1.014 0.984 1.083
hsa-miR-768-3p-4395188 1 1 1 1.126 1.075 0.985 1.015 1.267 1.148 1.165 1.219 1.09 0.928 1 1.006 1.062 1.143 1.158 0.978
MicroRNA expression in polarized macrophages
hsa-miR-769-5p-4395186 1 1 1 0.872 0.93 0.933 1.06 1.064 1.091 0.87 0.96 0.836 1.001 1.01 1.013 0.912 1.072 0.889 1.008
hsa-miR-801-4395183 1 1 1 1.078 0.827 2.117 1.147 0.834 3.958 2.779 2.466 3.508 1.128 0.875 4.592 1.341 1.980 2.918 2.198
hsa-miR-875-5p-4395314 1 1 1 0.949 0.685 2.103 0.82 0.637 1.805 0.64 0.687 1.863 1.195 0.438 1.861 1.246 1.087 1.063 1.165
hsa-miR-877-4395402 1 1 1 1.195 1.007 0.842 0.96 1.117 0.969 0.965 0.889 0.749 1.117 1.074 0.95 1.015 1.015 0.868 1.047
hsa-miR-885-5p-4395407 1 1 1 0.852 1.25 0.625 1.058 0.916 0.767 1.017 1.067 0.734 1.002 1.002 1.027 0.909 0.914 0.939 1.010
hsa-miR-886-5p-4395304 1 1 1 1.192 1.352 1.199 0.97 0.915 1.159 1.052 0.862 0.981 0.865 0.807 1.911 1.248 1.015 0.965 1.194
hsa-miR-9*-4395342 1 1 1 1.2 1.298 0.882 0.996 1.005 1.063 1.233 1.121 1.041 0.927 0.922 1.283 1.127 1.021 1.132 1.044
hsa-miR-92a-1*-4395248 1 1 1 2.048 0.901 0.917 1.495 1.463 1.856 1.2 0.69 1.123 1.106 0.587 1.107 1.289 1.605 1.004 0.933
hsa-miR-92a-4395169 1 1 1 1.159 1.109 1.01 1.061 0.939 0.971 0.98 0.932 0.899 0.963 0.809 0.899 1.093 0.990 0.937 0.890
hsa-miR-93*-4395250 1 1 1 0.902 1.009 0.904 0.989 1.18 1.057 1.02 1.009 1.015 0.932 0.969 0.98 0.938 1.075 1.015 0.960
hsa-miR-93-4373302 1 1 1 0.805 1.015 0.867 0.899 1.032 0.927 0.888 1.011 0.941 0.924 0.954 1.051 0.896 0.953 0.947 0.976
hsa-miR-941-4395294 1 1 1 0.854 1.257 0.48 1.052 1.049 1.056 0.561 1.06 0.374 0.745 1.192 0.935 0.864 1.052 0.665 0.957
hsa-miR-942-4395298 1 1 1 0.868 0.741 0.915 0.751 1.063 0.852 0.867 0.864 1.089 0.789 0.765 1.002 0.841 0.889 0.940 0.852
hsa-miR-9-4373285 1 1 1 0.718 1.148 1.219 0.696 0.94 1.069 0.752 1.027 1.094 0.615 0.776 0.961 1.028 0.902 0.958 0.784
hsa-miR-95-4373011 1 1 1 0.958 1.134 1.022 0.986 0.978 1.058 0.971 1.131 1.081 0.947 0.969 1.145 1.038 1.007 1.061 1.020
hsa-miR-99b*-4395307 1 1 1 0.911 1.143 0.879 0.79 1.278 0.756 1.442 1.207 0.581 1.115 1.25 0.77 0.978 0.941 1.077 1.045
Human MDMs were incubated in M1-, M2a-, M2b-, or M2c-polarizing conditions for 8 hours. RNA was collected and analyzed using a TaqMan Low Density Array from Applied Biosystems to determine miRNA expression. Data in the table indicate the fold change in expression of the indicated miRNA following exposure to polarizing treatment in each of three independent monocyte-derived macrophage (MDM) preparations. Changes in miRNA expression in treated relative to no treatment samples were calculated by the
Ct method, using RNU48 as an endogenous control. The mean fold change is indicated in the final 4 columns (n=3). D1 = MDM donor 1; D2 = MDM donor 2; D3 = MDM donor 3
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