peripheral neuropathy is the term for damage to nerves of the peripheral nervous...

• Peripheral neuropathy is the term for damage to nerves of the peripheral nervous system.

classification

• Anatomical

• Etiological :causes

• Pathological

• symptomology

Anatomical

• Mononeuropathy

• mononeuropathy multiplex

• Generalized: polyneuropathy

etiological

• acquired • VITAMIN D• V:vascuilities, SLE,PAN,..• I:infection,HIV,CMV,EBV,leprosy• T: truma • A:autimmune• M:Metabolic:DM,vit B12 defciency,hypothyrodism,renal hepatic ,porphyria• I:Infiltrative:sarcidosis, amylodosis • N:Neoplasm: paraneoplastic• D:Demyelinating ,GBS(Guillian barre syndrome or Drugs

• Hereditary

,

pathological

•

• Axonal

• demyelinating

• onset

• Acute chronic

Signs and symptoms

• Motor :weakness+ lower motor neuron signs

• Sensory: +ve or –ve symptoms, gloves and stalk distribution

• Autonomic:incotenance, postural hypotention,

Work UP

• EMG and nerve coduction study

• Look for the causes

• LP: protien, glu,WBC (cytoalbumin dissociation)..GBS

• ANA,RF,vit B12,TFT,Glu leve,renal,…

• Nerve biopsy

GBS

• Acute inflamatory demyelinating poly radiculopathy

• Preceded by URTI, diarrhea

• Asending weaknesss

• It is emergency

• Diagnosed by EMG ,NCS and LP(cyto albumin dissociation)