part 1 venous leg ulcers treatment and management · more than 80 million americans have vein...
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1Venous Leg Ulcers Treatment and Management: Understanding Chronic Venous Insufficiency and Venous Leg Ulcers © 2018 BSN Medical, Inc.
PART 1
VENOUS LEG ULCERS TREATMENT AND MANAGEMENT: UNDERSTANDING CHRONIC VENOUS INSUFFICIENCY AND VENOUS LEG ULCERS
1Venous Leg Ulcers Treatment and Management: Understanding Chronic Venous Insufficiency and Venous Leg Ulcers © 2018 BSN Medical, Inc.
VENOUS LEG ULCERS TREATMENT AND MANAGEMENT: UNDERSTANDING CHRONIC VENOUS INSUFFICIENCY AND VENOUS LEG ULCERS
INTRODUCTION
More than 80 million Americans have vein disease, including chronic venous
insufficiency (CVI), with 40% of women and 20% of men having significant problems
by age 50.1 These disorders have a very high rate of recurrence and can develop
into more serious conditions such as venous leg ulcers (VLUs). This makes caring
for patients with CVI or VLU incredibly costly for patients and health care providers.2
VLU care is estimated at $3 billion annually, thus making it a significant burden on
the health care system.3–5 Understanding the causes, risk factors, and best practice
treatment and management options is critical to reducing the risk of complications,
optimizing outcomes for patients, and minimizing costs.
2Venous Leg Ulcers Treatment and Management: Understanding Chronic Venous Insufficiency and Venous Leg Ulcers © 2018 BSN Medical, Inc.
CAUSES OF CVI
Open valve Blood can flow
Closed valve Blood can not flow back to the heart
Insufficient valves cause venous reflux
CVI results from weak or damaged valves that allow backflow of blood in the veins. This leads to blood pooling, enlarged veins, and blood clots. Untreated, CVI can progress through several stages, ultimately leading to VLUs. Being able to identify these stages and taking steps to slow or halt the progression are important for improving patients’ outcomes. Utilizing a classification system such as CEAP (Clinical, Etiology, Anatomic, and Pathophysiology) designed to help identify each stage can help health care professionals take steps to prevent VLUs and monitor patients’ conditions.6
CEAP CLASSIFICATION SYSTEM C=Clinical picture E=Etiology A=Anatomy P=Pathophysiology
C0S
Patients may be experiencing possible symptoms of CVI such as a heavy sensation in the legs, pain, and pruritus. However, at this stage there are no clinical signs of CVI. Health care professionals should regularly check at-risk patients for signs of development6
C1 Telangiectasia or reticular veins may be present C2 Varicose veinsC3 Edema
C4a Pigmentation and/or eczemaC4b Lipodermatosclerosis and/or atrophie blanche C5 Healed venous ulcer C6 Active venous ulcer
Chronic Venous Insufficiency: DiagnosisInternational Consensus CEAP
Sym
ptom
sCl
inic
al s
igns
CoS
C1
C2
C3
C4
C5
C6
Heavy legs, pains in the legs, pruritus... But no clinical or palpable signs of venous disease
Visible and palpable varicose veins
Trophic changes of venous origin: atrophie blanche, pig-mented purpuric dermatitis, varicose eczema
Telangiectasia or reticular veins
Venous oedema (without trophic changes)
healed ulcer with trophic changes
Presence of one or more active venous leg ulcers, often ac-companied by trophic changes
Vascular System - Anatomy and Physiology
Venous System Components• Superficial system veins• Deep system veins • Perforators or connectors
Venous Return Influencers • Heart• Respiratory pump• Venous valves• Venous tone• Calf muscle pump
3Venous Leg Ulcers Treatment and Management: Understanding Chronic Venous Insufficiency and Venous Leg Ulcers © 2018 BSN Medical, Inc.
Swelling / Edema
Deep Vein Thrombosis
Varicose Veins
Venous Leg Ulcer (VLU)
Chronic Venous Insufficiency: Conditions
Etiology: What is a VLU?
Venous insufficiency causes peripheral tissue breakdown
Blood in legs “pool” due to inability of the venous system to carry it away
• Irregular borders• Superficial (shallow)• Heavy drainage• Painful• Swollen lower extremity• Medial>Lateral side of the ankle
Etiology: VLU Characteristics
At each stage of disease progression, it is important for health care professionals to reevaluate treatment and take steps to impede or reverse the process. This means following best treatment practices and taking a proactive approach. Increasingly, research shows that successful treatment of VLUs requires a combination of compression therapy and optimal wound healing conditions. This allows patients to heal rapidly while reducing the risk of recurrence.5
THE HIGH COSTS OF CVI AND VLUSCVI is a chronic illness with potentially serious complications, including VLUs. These complications also have a high rate of recurrence, meaning that patients often struggle with CVI and VLUs for the remainder of their lives. Therefore, these conditions have a significant impact, both on patients’ quality of life and on costs. This situation makes it important for health care professionals to follow current best practice guidelines for care and to work to prevent recurrence.1,2
Impact on Patients
CVI can dramatically affect patients’ well-being including significant discomfort, swelling, tension and pain, all of which limit mobility. Blood pooling caused by CVI can also lead to blood clots, which can be debilitating or life threatening, particularly if they lead to strokes. This makes it important that health care professionals promote good circulation through compression therapy.6
VLUs resulting from CVI are also common, accounting for between 60% and 80% of all leg ulcers. These ulcers often require significant treatment and can lead to longer hospital stays and recurring complications. VLUs can also be debilitating and dangerous for patients and can lead to reduced mobility, severe pain, infection, amputation, and death.7
Financial Costs
CVI and VLUs also have major financial implications for patients and health care professionals. VLUs in particular require significant care, can be slow to heal, and have a high rate of recurrence. These factors combine to make VLUs a major burden on the health care system. Recent estimates show that the cost of treatment of VLUs per patient in the United States is $10,000 to $12,000 per year, with the average lifetime cost of care greater than $40,000.8 Implementing practices that help reduce rates of recurrence and improve healing time could significantly reduce these costs while improving patients’ outcomes.
ValveValve prevents
backwards bloodflow
Normal venous function Venous insufficiency
Faulty valve allows backwards bloodflow
4Venous Leg Ulcers Treatment and Management: Understanding Chronic Venous Insufficiency and Venous Leg Ulcers © 2018 BSN Medical, Inc.
PREVENT RECURRENCE
Cutimed® Sorbion® Sorbact® featuring Bacteria-binding
Technology
Cutimed® Sorbion Sachet® Superabsorbent
Dressing
Cutimed Epiona® Native Collagen
Dressing
JOBST® Compression
Therapy
JOBST® Graduated Compression
Legwear
REBUILD TISSUE
REMOVE
EXUD
ATE
AND
BACT
ERIA
REDUCE EDEM
A
PREVENT RECURRENCE
Cutimed® Sorbion® Sorbact® featuring Bacteria-binding
Technology
Cutimed® Sorbion Sachet® Superabsorbent
Dressing
Cutimed Epiona® Native Collagen
Dressing
JOBST® Compression
Therapy
JOBST® Graduated Compression
Legwear
REBUILD TISSUE
REMOVE
EXUD
ATE
AND
BACT
ERIA
REDUCE EDEM
A
BEST PRACTICE TREATMENT OPTIONS FOR CVI AND VLUSTo manage CVI and VLUs effectively, it is critical that health care professionals take proactive measures using an integrated approach to management, combining compression therapy with treatments that support optimal wound healing. A multistep approach that combines effective modern treatments with rapid evaluation and risk factor identification can help minimize risks to patients and reduce the risk of recurrence.5
Understand Risk Factors – Identifying at-risk individuals and factors that could exacerbate their condition is critical to CVI management. Common risk factors include obesity, lack of exercise, hormonal changes, smoking, and alcohol use. Eliminating or reducing these risk factors can help prevent or reverse the progression of CVI and reduce the risk of VLU recurrence. It is also important for health care professionals to understand the current state of the patient’s CVI and to classify the patient’s condition according to the CEAP system. This will help create a more effective plan for treatment that effectively addresses the patient’s needs.6
Define Treatment Goals – An effective care plan for CVI and VLUs should treat the underlying lack of circulation, minimize or eliminate perpetuating factors, create the optimal environment for wound healing, and minimize the risk of recurrence. Accomplishing these goals requires an integrated approach to treatment that promotes wound healing and utilizes compression therapy to improve circulation.
BSN Medical, Inc Integrated Therapy Solutions
BSN medical, Inc offers an integrated approach to CVI and VLU treatment. Our system helps remove exudate and bacteria, rebuild tissue, reduce edema with compression therapy and prevent recurrence with JOBST compression legwear.9 This combined approach can help health care professionals effectively treat more VLUs and prevent recurrence.6,7
In the following section we will explain the remove and rebuild steps of the system. In the next white paper in our series, we will explain the reduce and prevent steps of the VLU recommended model (see following images):
Remove – Exudate and bacteria can impede healing and lead to infection and more serious complications. BSN’s integrated therapy solutions promote rapid
healing and reduce the risk of infection by safely and
irreversibly binding bacteria, so cell debris is safely removed from
the wound bed with Cutimed® Sorbion®Sorbact®. This dressing has no release of chemically active agents and eliminates the risk of bacterial resistance to manage infections, as well as absorb exudate to reduce maceration, thus optimizing the VLU healing environment and improving patients’ outcomes.5,6
Rebuild – VLUs can be slow to heal due to their complicated
nature. BSN’s Integrated Therapy Solutions use a collagen dressing to help heal the wound. Cutimed® Epiona is a native bovine collagen dressing with a porous 3D matrix technology
that helps rebuild new tissue in stalled wounds. Epiona
is developed with the same microstructure as the intact collagen
network of human skin, allowing it to capture and bind excessive proteases and MMPs to help protect the growth factors that stimulate healing.5,6
CONCLUSIONIf health care professionals are not proactive, CVI can rap-idly progress, leading to VLUs and other serious compli-cations. It is important to understand the risk factors and progression stages of the disease, to take preventative measures and prevent recurrence. Outcomes for patients can also be improved by taking an integrated approach to management and treatment, combining therapies that work synergistically for healing and prevention.
BSN Medical’s Integrated Therapy Solution encourages an integrated approach to CVI and VLU treatment. By helping to remove exudate and bacteria, rebuild tissue, and reduce edema with compression therapy, this system helps to promote rapid and complete VLU healing while treating the underlying cause. Health care professionals will then be able to treat VLUs more effectively, prevent VLU recurrence, and thereby improve the quality of their patients’ lives - all while reducing costs.
BSN Medical, Inc., an Essity Company 5825 Carnegie Blvd, Charlotte, NC 28209-4633 Tel. (+1) 704 554 9933 Fax (+1) 704 358 4558 To order toll-free: BSN medical (+1) 800 552 1157 © 2018 BSN medical Inc.
PREVENT RECURRENCE
Cutimed® Sorbion® Sorbact® featuring Bacteria-binding
Technology
Cutimed® Sorbion Sachet® Superabsorbent
Dressing
Cutimed Epiona® Native Collagen
Dressing
JOBST® Compression
Therapy
JOBST® Graduated Compression
Legwear
REBUILD TISSUE
REMOVE
EXUD
ATE
AND
BACT
ERIA
REDUCE EDEM
A
PREVENT RECURRENCE
Cutimed® Sorbion® Sorbact® featuring Bacteria-binding
Technology
Cutimed® Sorbion Sachet® Superabsorbent
Dressing
Cutimed Epiona® Native Collagen
Dressing
JOBST® Compression
Therapy
JOBST® Graduated Compression
Legwear
REBUILD TISSUE
REMOVE
EXUD
ATE
AND
BACT
ERIA
REDUCE EDEM
A
CLICK HERE to have a BSN Medical representative contact you.
5Venous Leg Ulcers Treatment and Management: Understanding Chronic Venous Insufficiency and Venous Leg Ulcers © 2018 BSN Medical, Inc.
REFERENCES
1. Eberhard R, Pannier-Fischer F, Bromen K, et al. Bonn Vein Study by the German Society of Phlebology: epidemiological study to investigate the prevalence and severity of chronic venous disorders in the urban and rural residential populations. Phlebologie. 2003;32:1–14.
2. Ratliff CR, Yates S, McNichol L, Gray M. Compression for primary prevention, treatment and prevention of recurrence of venous ulcers: an evidence and consensus based algorithm for care across the continuum. J Wound Ostomy Continence Nurs. 2016;43(4):347–64.
3. Eberhardt RT, Raffetto JD. Chronic venous insufficiency. Circulation. 2014;130(4):333–46.
4. Laing W. Chronic Venous Diseases of the Leg. London, UK: Office of Health Economics; 1992:1–44.
5. Pierce GF, Mustoe TA. Pharmacologic enhancement of wound healing. Annu Rev Med. 1995;46:467–81.
6. Sullivan C. Chronic venous insufficiency & VLUs: clinical overview. Charlotte, NC: BSN Medical; 2015.
7. Vasudevan B. Venous leg ulcers: pathophysiology and classification. Indian Dermatol Online J. 2014;5(3):366–70.
8. Ma H, O’Donnell TF Jr, Rosen NA, Iafrati MD. The real cost of treating venous ulcers in a contemporary vascular practice. J Vasc Surg Venous Lymphat Disord. 2014;2(4):355–61.
9. JOBST Compression Legwear Consumer Strategic Research Report. Anerca, 2015.
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