pablo artal - university of...

Adaptive Optics visualsimulator

(…and depth of focus)

Pablo ArtalLABORATORIO DE OPTICA

UNIVERSIDAD DE MURCIA, SPAIN8th International Wavefront Congress, Santa Fe, USA, February

2007

New LO·UM building!

Supported by:

PedroPrieto

SilvestreManzanera

DiegoAyala

&

JoeLindacher

Active element

Aberration correction with AdaptiveOptics

Aberrated eye

+

+

=

Corrected eye

=

Phase manipulation with AO

Original eye

+

Active element

+

=

Modified eye

=

Visual simulation

sXIII defocus

Using the AO visualsimulator to search for

better solutions forpresbyopia…

using phase masks!

NO accommodation

Adding phase mask

0 1 2 3 40.00.20.40.60.81.0

Defocus (D)

Strehl

0 1 2 3 40.00.20.40.60.81.0

Defocus (D)

Strehl

Spectra of Zernike modes with and without paralyzedaccommodation for 4.7 mm pupil

Adaptive opticsVISUAL SIMULATOR

Interactivedesign/testing of

new ophthalmic devices

Presbyopic corrector designprocedure

Phase profile design

Prototype implementation

Mass production

Clinical testing

Phase profile design

Prototype implementation

Mass production

Clinical testing

Adaptive opticsvisual simulator

Presbyopic corrector designprocedure

Spatiallight

modulator

Stimuligenerator

Subject

H-S

E

?

Visualtestin

g

Induced phase

Hamamatsu X8627

Active element: Liquid crystal programmable phasemodulator

Advantages against deformable mirrors:_ High fidelity: no need of close-loopoperation_ No continuity constrains: steep phasechanges allowed_ High phase range (ideal for presbyopiczones)

Diode laser780 nm

Focus / vergencecontrol

Pupil

Cold mirror

StimuliGenerator

Polarizer

E

Beamsplitter

Modulator

Subject

Induced phase

LASER633 nm

Pupil

Spatialfilter

Hartmann-Shack

Adaptive Optics Visual Simulator

CCD camera

StimuliGenerator

CCD camera

E

Pupil

LASER633 nm

Pupil

Spatialfilter Focus / vergence

control

Polarizer

Beamsplitter

Modulator

Subject

Induced phase

Hartmann-Shack

Diode laser780 nm

Aberration measurement and couplingstudiesCold mirror

0 Dp1.4 Dp

2.8 Dp

Focus / vergencecontrol

Pupil

Cold mirror

Polarizer

Beamsplitter

Modulator

Hartmann-Shack

Subject

Induced phase

LASER633 nm

Pupil

Spatialfilter

CCD camera

Objective estimation of depth of focus

0 Dp1.4 Dp

2.8 Dp

Focus / vergencecontrol

Pupil

Cold mirror

Polarizer

Beamsplitter

Modulator

Hartmann-Shack

Subject

Induced phase

LASER633 nm

Pupil

Spatialfilter

CCD camera

Defocus (Dp)0 1 2 3

0.0

0.2

0.4

0.6

0.8

1.0TheoreticalExperimental

Stre

hl

Bifocal profile

Defocus (Dp)0 1 2 3

0.0

0.2

0.4

0.6

0.8

1.0TheoreticalExperimental

Trifocal profile

Stre

hl

Objective estimation of depth of focus

PHASEDESIGN SOFTWARE GRAY-LEVEL

IMAGE

SLM

LO·UM_AO_visualsimulator

RELAY-OPTICSVISUAL

TESTING

smile

Hartmann-Shack

LASER633 nm

Pupil

Spatialfilter

CCD camera

Diode laser780 nm

Focus / vergencecontrol

Pupil

Cold mirror

StimuliGenerator

Polarizer

E

Beamsplitter

Modulator

Subject

Induced phase

Subjective depth of focus

Defocus (D)0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5

'x' size (min)

468

10121416182022

no phasephase A phase B

E

Depth of focus with different phaseprofiles

The best phases can bemanufactured

as contact lenses…

E

AOVS ON

E

Prototype checking

AOVS OFF

Stimulus vergence (Dp)0 1 2 3

0.000.050.100.150.200.25

Estimulus vergence (D)0 1 2 3

Reading perform

. (1/m

in) 0.000.050.100.150.200.25 2.4 mm pupil 3.6 mm pupil

Phase on actual contact lensPhase produced by the PPM inthe AO system

Subject: PA Subject: PA

Goodagreement!

Prototype checking

· Adaptive Optics used assimulator is a powerful tool tobetter understand how opticsaffects vision and to develop newand improved ophthalmicsolutions

· In particular, we havedemonstrated its potential toevaluate the depth of focus ofdifferent phase profiles to correctpresbyopia

Conclusions

· The performance predicted withthe AO system and that obtainedwith actual lenses were in quite agood agreement

· This AO approach can saveseveral steps in currentprocedures for contact lens designand eventually lead to improvedvisual solutions

Conclusions